CN105853221A - Anti-radiation dosing, split-charging and injection device and method - Google Patents
Anti-radiation dosing, split-charging and injection device and method Download PDFInfo
- Publication number
- CN105853221A CN105853221A CN201610252433.5A CN201610252433A CN105853221A CN 105853221 A CN105853221 A CN 105853221A CN 201610252433 A CN201610252433 A CN 201610252433A CN 105853221 A CN105853221 A CN 105853221A
- Authority
- CN
- China
- Prior art keywords
- bottle
- liquid
- valve
- dosing
- liquid dispenser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1002—Intraluminal radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1014—Intracavitary radiation therapy
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/02—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
- B67C3/22—Details
- B67C3/26—Filling-heads; Means for engaging filling-heads with bottle necks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
- G01T1/16—Measuring radiation intensity
- G01T1/17—Circuit arrangements not adapted to a particular type of detector
- G01T1/178—Circuit arrangements not adapted to a particular type of detector for measuring specific activity in the presence of other radioactive substances, e.g. natural, in the air or in liquids such as rain water
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N2005/1019—Sources therefor
- A61N2005/1021—Radioactive fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Fluid Mechanics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Molecular Biology (AREA)
- High Energy & Nuclear Physics (AREA)
- General Physics & Mathematics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses an anti-radiation dosing, split-charging and injection device and method. The device comprises a dosing and injection unit, an external port and an anti-radiation isolation tank, wherein the dosing and injection unit is arranged in the anti-radiation isolation tank and comprises a source liquid bottle, a normal saline bottle, a waste liquid bottle, a measurement bottle, an activity measuring instrument, a dosing device, a dosing device linkage unit and a controller, and the activity measuring instrument is used for measuring activity of a medicine liquid in the measurement bottle in real time; an inlet of the dosing device is connected with the source liquid bottle, the measurement bottle and the normal saline bottle through pipelines provided with valves respectively, and an outlet of the dosing device is connected with the waste liquid bottle and the external split-charging and injection port through pipelines provided with valves respectively. According to the device and the method, the problems of transfer, split-charging and injection of the radioactive source liquid are integrally solved, split-charging and injection can be performed manually or automatically, all parts contacted with a drug can be replaced, so that external pollution and external radiation to the drug are avoided, and meanwhile, the pollution of the drug to the machines is also avoided.
Description
Technical field
The present invention relates to radioprotective dosing, subpackage and injection field, particularly a kind of radioprotective dosing, subpackage and injection dress
Put and method.
Background technology
Under the present conditions, the radiopharmaceutic subpackage of Nuclear Medicine Department and injection, need operator hand-held equipped with putting the most by force
The liquid dispenser of penetrating property medicine carries out subpackage or injection.It is the most up to a hundred that some hospitals need the patient of injection to reach tens people every day
People, personnel lack omnidistance protection in subpackage and injection process, and the medical exposure intensity that injector suffers is the highest, and this is right
Injector brings great potential health threat.Meanwhile, subpackage and injection process need safe and reliable device,
To ensure that subpackage and injection process do not cause the pollution of protective equipment.
Further, needing to ensure the accuracy of subpackage when medicine subpackage, to improve subsequent use effect, this is just as far as possible
The process to subpackage that is required to carries out real-time property of medicine detection, and carries out accurate subpackage according to detection data, to ensure note
The dosage penetrating medicine is accurate.The when that Nuclear Medicine Department relating to medicine subpackage, the injection dosage of patient is often with subpackage personnel's
Reported doses is as the criterion, and the reported doses of subpackage personnel can not accurately determine the dosage of liquid dispenser, so injects the dosage of medicine
Not accurate enough.
Meanwhile, in practical operation, subpackage and injection are two links separated, and which adds radiation and pollute anti-
The difficulty protected, causes injection not in time simultaneously, adds radiopharmaceutic decay, make the big discounting of dosage of injection medicine
Button.
Summary of the invention
It is an object of the invention to provide a kind of radioprotective dosing, subpackage and injection device and method.
The technical scheme realizing the object of the invention is: a kind of radioprotective dosing, subpackage and injection device, injects including dosing
Unit, external interface and radioprotective shielded box, dosing injecting unit is arranged in radioprotective shielded box, and described dosing is injected
Unit includes source liquid bottle, normal saline bottle, waste liquid bottle, measurement bottle, measures the work of bottle inner liquid medicine activity for measurement in real time
Degree measuring instrument, liquid dispenser, liquid dispenser linkage unit and controller；
The entrance of described liquid dispenser is connected with measurement bottle, source liquid bottle and normal saline bottle respectively by valve, described liquid dispenser
Outlet be connected with waste liquid bottle and external interface respectively by valve；
Described controller is used for receiving external command, determines source liquid measure and the saline volume needing extraction；Controller and work
Degree measuring instrument communication, measures medicinal liquid activity in real time, controls liquid dispenser and controls valve opening and closing, completing dosing, subpackage or note
Penetrate；
Described liquid dispenser linkage unit is for receiving the signal that controller sends according to source liquid measure and saline volume, and driving is joined
In the liquid device extraction source endogenous liquid of liquid bottle and normal saline bottle, normal saline is to measuring bottle mixing, and is carried out point by external interface
Dress or injection；
Described waste liquid bottle is used for holding detergent line or unwanted surplus liquid.
A kind of radioprotective dosing, subpackage and injecting method, comprise the following steps:
Determine the medicinal liquid activity needing to use according to formula, and determine source liquid measure and the saline volume of needs；
Opening the valve between liquid dispenser and source liquid bottle, control the quantitative source liquid of liquid dispenser extraction and enter measurement bottle, activity is surveyed
Activity in bottle measured in real time by amount instrument, and controls to enter the source liquid measure in bottle；
Close the valve between liquid dispenser and source liquid bottle, open the valve between liquid dispenser and normal saline bottle, according to formula
Extract quantitative saline volume, and be injected in measurement bottle and mix, after completing, close valve；
Open the valve measured between bottle and liquid dispenser, admixing medical solutions is drawn in liquid dispenser, completes dosing；
Open the valve between liquid dispenser and external interface, close other valves, according to the fltting speed set, automatically or
Manually advance the push rod of liquid dispenser, the medicinal liquid in liquid dispenser is delivered to external interface, complete subpackage or injection.
Compared with prior art, the remarkable result of the present invention is:
(1) present invention realizes totally enclosed drug detection and proportioning by radioprotective shielded box, and medicine can lead on request
Cross controller and realize accurate proportioning；
(2) present invention can carry out automatic liquid matching or select manual dosing, and during automatic liquid matching, system drives motor automatically
Extraction solution；During manual dosing, manual withdrawal liquid dispenser, coordinate internal valves and liquid dispenser push rod position position sensor,
Accurately extract solution；The present invention can also carry out automatic subpackaging or injection and manual subpackage or injection, by electricity when being automatically brought into operation
Machine drives and carries out liquid dispenser, is controlled internal hydraulic pressure push rod by external hydraulic push rod and be operated manually time manual；
(3) present invention uses and measures the mode that bottle separates with liquid dispenser, it is achieved that in dosing, liquid is carried out real-time activity
Measure, and after completing dosing, liquid leaves measuring instrument, it is achieved the protection to measuring instrument；
(4) hardware of the present invention the most directly contacts with medicine, and all have the pipeline contacted and the bottle all can be more with medicine
Change, ensured that medicine, without outside contamination, also avoids the medicine pollution to machine simultaneously；
(5) present invention has automatic cleaning function, reduces the dead space capacity after every time using, and reduces residual radiation；
(6) present invention uses activity meter in real time source liquid activity is detected and shown, according to measured value and medicine
The needs of proportioning, carry out accurate proportioning to medicine；The present invention can show that liquid dispenser amount of solution, activity meter are surveyed in real time
Amount result, valve break-make and shielding case lid open and-shut mode.
Accompanying drawing explanation
Fig. 1 is the outside schematic diagram of the radioprotective dosing of the present invention, subpackage and injection device.
Fig. 2 is the radioprotective dosing of the present invention, subpackage and injection device structure chart.
Fig. 3 is the liquid dispenser linkage unit structure chart of the present invention.
Fig. 4 is the stepper assemblies schematic diagram of the present invention.
Fig. 5 is the External infusion joint design figure of the present invention.
Fig. 6 is that the pipeline of the present invention connects schematic block diagram.
Fig. 7 is the system functional block diagram of the present invention.
Fig. 8 is the dosing flow chart of the present invention.
Fig. 9 is the automatic/hand injection flow chart of the present invention.
Detailed description of the invention
In conjunction with Fig. 1, Fig. 2, a kind of radioprotective dosing, subpackage and the injection device of the present invention, including dosing injecting unit,
External interface 42 and radioprotective shielded box, dosing injecting unit is arranged in radioprotective shielded box, and described dosing injection is single
Unit includes source liquid bottle 14, normal saline bottle 16, waste liquid bottle 17, measurement bottle 4, medicine in measuring bottle 4 in real time
The activity meter 29 of liquid activity, liquid dispenser 25, liquid dispenser linkage unit and controller；
The entrance of described liquid dispenser 25 is connected with measurement bottle 4, source liquid bottle 14 and normal saline bottle 16 respectively by valve,
The outlet of described liquid dispenser 25 is connected with waste liquid bottle 17 and external interface 42 respectively by valve；
Described controller is used for receiving external command, determines source liquid measure and the saline volume needing extraction；Controller and work
Degree measuring instrument 29 communication, measures medicinal liquid activity in real time, controls liquid dispenser and controls valve opening and closing, completing dosing, subpackage
Or injection；
Described liquid dispenser linkage unit, for receiving source liquid measure and the saline volume that controller sends, drives liquid dispenser 25
In the endogenous liquid of extraction source liquid bottle 14 and normal saline bottle 16, normal saline mixes to measuring bottle 4, and by external interface 42
Carry out subpackage or injection；
Described waste liquid bottle 17 is used for holding detergent line or unwanted surplus liquid.
Further, described liquid dispenser linkage unit includes liquid dispenser driving means 21 and position sensor 23, described in join
Liquid device driving means 21 is used for driving liquid dispenser 25 to carry out extraction；Described position sensor 23 is used for determining liquid dispenser 25
The displacement amount of push rod.
Further, described liquid dispenser linkage unit also includes that limit switch 30, described limit switch 30 are joined for restriction
Liquid device driving means 21 extreme position.
Further, described liquid dispenser driving means 21 includes internal hydraulic pressure push rod 26 and external hydraulic push rod, described interior
Portion's hydraulic push rod 26 is used for driving liquid dispenser 25 to carry out extraction, and described external hydraulic push rod is joined with internal hydraulic pressure push rod 26
Close, constitute manual fluid body.
Further, described valve includes the first valve, the second valve, the 3rd valve, the 4th valve and the 5th valve,
Described first valve is arranged on liquid dispenser 25 and measures between bottle 4, and described second valve is arranged on liquid dispenser 25 and source liquid
Between bottle 14, described 3rd valve is arranged between liquid dispenser 25 and normal saline bottle 16, and described 4th valve is arranged
Between liquid dispenser 25 and waste liquid bottle 17, described 5th valve is arranged between liquid dispenser 25 and external interface 42.
Further, described first valve, the second valve, the 3rd valve, the 4th valve and the 5th valve are break-make type
Valve.
Further, described radioprotective shielded box includes casing, case lid 11 and stepper assemblies；Described motor
Assembly is used for receiving controller instruction, controls case lid 11 opening and closing.
Further, described external interface 42 connects exterior tube joint 19, and exterior tube joint 19 is provided with check valve
15。
Further, described device also includes display unit and operation button, in described display unit shows liquid dispenser in real time
Solution volume；Described operation button includes function menu button, system switching button and cover switch button, for control
Device processed sends instruction and realizes automatic liquid matching, automatic subpackaging or injection, system switching and case lid opening and closing.
The present invention also provides for a kind of radioprotective dosing, subpackage and injecting method, comprises the following steps:
Determine the medicinal liquid activity needing to use according to formula, and determine source liquid measure and the saline volume of needs；
Opening the valve between liquid dispenser and source liquid bottle, control the quantitative source liquid of liquid dispenser extraction and enter measurement bottle, activity is surveyed
Activity in bottle measured in real time by amount instrument, and controls to enter the source liquid measure in bottle；
Close the valve between liquid dispenser and source liquid bottle, open the valve between liquid dispenser and normal saline bottle, according to formula
Extract quantitative saline volume, and be injected in measurement bottle and mix, after completing, close valve；
Open the valve measured between bottle and liquid dispenser, admixing medical solutions is drawn in liquid dispenser, completes dosing；
Open the valve between liquid dispenser and external interface, close other valves, according to the fltting speed set, automatically or
Manually advance the push rod of liquid dispenser, the medicinal liquid in liquid dispenser is delivered to external interface, complete subpackage or injection.
The invention will be further described with specific embodiment below in conjunction with the accompanying drawings.
Embodiment
In conjunction with Fig. 1, Fig. 2, a kind of radioprotective dosing, subpackage and injection device, connect including dosing injecting unit, outside
Mouth 42 and radioprotective shielded box, dosing injecting unit is arranged in radioprotective shielded box, and described dosing injecting unit includes
Source liquid bottle 14, normal saline bottle 16, waste liquid bottle 17, measure bottle 4, measure bottle 4 inner liquid medicine activity in real time
Activity meter 29, liquid dispenser 25, liquid dispenser linkage unit and controller；
The entrance of described liquid dispenser be provided by the pipeline of valve respectively with source liquid bottle 14, measure bottle 4 and normal saline bottle
16 connect, and the outlet of described liquid dispenser is provided by the pipeline of valve and is connected with waste liquid bottle 17 and external interface respectively；
The control output end of described controller is connected with valve, liquid dispenser linkage unit respectively, the letter of described activity meter 29
Number outfan is connected with the signal input part of controller.
Described measurement bottle 4 is placed in activity meter 29 and measures in cavity, the institute of detection in real time vehicle during dosing
Activity, transfers to liquid dispenser 25 from measurement bottle 4 after completing dosing.
As it is shown on figure 3, described liquid dispenser linkage unit includes that liquid dispenser driving means 21, liquid dispenser guide line slide rail group
Part 22, sensor 23, clutch 24, limit switch 30, connecting plate 31 and internal hydraulic pressure push rod 26, described interior
Portion's hydraulic push rod 26 is connected by pipeline external hydraulic push rod 6, external hydraulic push rod 6 and internal hydraulic pressure push rod 26 groups
Become man-operated mechanism；
The push rod of liquid dispenser 25 is connected with internal hydraulic pressure push rod 26 and clutch 24 respectively by connecting plate 31, described
Connecting plate coordinates at liquid dispenser guiding line slide rail assembly 22 bottom connecting plate with arranging, stretching out of described clutch 24
Axle coordinates with liquid dispenser driving means 21, controls liquid dispenser driving means 21 closed and disconnected, specially clutch 24
Projecting shaft coordinate with the motor screw block of liquid dispenser driving means 21, when the projecting shaft of clutch 24 stretches out, join
The motor screw block of liquid device driving means 21 is connected with clutch 24, now controls liquid dispenser driving means 21 and drives
Liquid dispenser 25 pushrod movement；When the projecting shaft of clutch 24 is retracted, the motor screw of liquid dispenser driving means 21
Block separates with clutch 24, now by operation external hydraulic push rod 6, liquid dispenser 25 push rod is carried out Non-follow control；
As it is shown in figure 1, be provided with hand injection push rod outer housing 5 outside external hydraulic push rod 6, open when using hand injection
Outer housing, covers outer housing when not using；
Described position sensor 23 is connected with connecting plate 31, measures liquid dispenser push rod position in real time, in determining liquid dispenser
Liquid capacity, described limit switch 30 is used for determining liquid dispenser driving means 21 position, and liquid dispenser linkage unit is arranged on
On installing plate 32.
As shown in Figure 4, radioprotective shielded box includes casing, case lid 11 and stepper assemblies, described casing and case lid
11 use lead casing and lead case lids, described source liquid bottle 14, measure bottle 4, activity meter 29, normal saline bottle 16,
Waste liquid bottle 17, liquid dispenser 25 and liquid dispenser linkage unit are arranged in lead casing；Lead casing top is provided with support type
Material assembly 12, supports and is provided with lead case lid slide rail 13 on section bar component 12, and lead case lid both sides are sliding with lead case lid slide rail 13
Dynamic cooperation, lead case lid slide rail 13 both sides are provided with case lid limit switch 37, and case lid limit switch 37 controls lead case lid 11
Extreme position；
Described stepper assemblies includes case lid motor 33, screw mandrel 36, screw mandrel screw block 35 and is furnished with Timing Belt
Synchronous pulley 39；Lead case lid is connected with screw mandrel screw block 35 by connecting aluminum corner brace 34, and case lid motor is by installing
Aluminum corner brace 40 is fixedly installed on support section bar component 12, and is connected with screw mandrel 36 by synchronous pulley 39, screw mandrel 36
Fix seat 38 by screw mandrel to be fixed on support section bar component 12；The control output end of described controller and case lid stepping electricity
Machine connects.
As it is shown in figure 5, described external interface 42 is connected with exterior tube joint 19, exterior tube joint 19 is provided with list
To valve 15, prevent exterior materials from entering device.
Described measurement bottle 4, source liquid bottle 15, normal saline bottle 16, waste liquid bottle 17, liquid dispenser and connecting line 20 are equal
For demountable structure.
Radioprotective dosing, subpackage and injection device also include display unit 2 and operation button 3, and described display unit is respectively
It is connected with controller, is used for showing that feature operation menu and medicinal liquid capacity show figure in real time；Described operation button includes merit
Can menu button, system switching button and cover switch button, be respectively used to control system function menu content, system is opened
Close and case lid opening and closing.
The menu control of display unit includes: upper and lower, confirmation, menu, control set of time, shielded box safe opening
Time interval is arranged, automatic or manual dosing；
Operation button includes but not limited to the following button:
Dosing key: according to the source liquid measure set and saline volume, normal saline and source liquid hold-up proportioning can be inputted, and select
Select automatic liquid matching or manual dosing；
Injection key: press injection and carry out, the injection that comes loose stops；
Manual/auto switch key: it is manual for pressing lamp bright, and drawer lock is opened, and allows and opens drawer, carries out hands
Dynamic operation；
Uncap key: press rear drive motor, open upper cover；
Close Gai Jian: press rear drive motor, close upper cover；
Power switch key: open and close system；
Emergent stopping key: when fortuitous event occurs in whole system, carries out power-off to motion control portion.
As shown in Figure 6, described valve includes the first valve, the second valve, the 3rd valve, the 4th valve, the 5th valve；
Wherein, the first valve is arranged on the pipeline between liquid dispenser 25 and measurement bottle 4, and the second valve is arranged on liquid dispenser 25
And on the pipeline between source liquid bottle 14, the 3rd valve is arranged on the pipeline between liquid dispenser 25 and normal saline bottle 16,
4th valve is arranged on the pipeline between liquid dispenser 25 and waste liquid bottle 17, and the 5th valve is arranged on liquid dispenser 25 with outer
On pipeline between portion's interface；Preferably, the valve of the present invention uses pinch valve 18, and is provided with light electric-examination on pinch valve
Whether slowdown monitoring switch, be in place for signal piping.
In conjunction with Fig. 7, the controller of the present invention respectively with display unit, activity meter 29, case lid motor 33, case
Lid limit switch 37, liquid dispenser driving means 21, position detector 23, clutch the 24, first～the 5th valve are even
Connect, it is achieved man-machine interaction, source liquid activity measurement, case lid control, the detection of case lid position, the control of dosing/subpackage/injection,
The detection of liquid dispenser position, automatic/hand switching, Valve controlling and state-detection；Wherein state-detection includes Guan Weijian
Survey, case lid state-detection, manually detection and ID detection, the detection of pipe position refers to whether pipeline is put well in valve, case lid
State-detection refers to that case lid opens and closes two states detection.
Device also includes casing 1, and described display unit 2, operation button 3, external hydraulic push rod 6 are arranged at
Cover top portion, external hydraulic push rod 6 is outside is provided with hand push rod outer housing 5, and described lead case lid top is additionally provided with cabinet
Sliding panel 7；Described casing side is provided with sub-bottling or the hand steered plate of patient, the outside being connected with exterior tube joint 19
Injection needle adapter 9 extends above from the hand steered plate of patient 8, it is simple to patient injection medicament；
In conjunction with Fig. 8, a kind of radioprotective dosing method based on above-mentioned radioprotective dosing, subpackage and injection device, including with
Lower step:
S11, inputs formula or calls the formula stored, determining required source liquid activity according to formula；
S12, opens the valve between liquid dispenser and source liquid bottle, the source liquid entrance measurement bottle that liquid dispenser extraction is quantitative, and real
Time show measurement bottle source liquid activity；
S13, closes the valve between liquid dispenser and source liquid bottle, opens the valve between liquid dispenser and normal saline bottle, press
According to the formula quantitative saline volume of extraction, and it is injected in measurement bottle and mixes, after completing, close valve；
S14, opens the valve measured between bottle and liquid dispenser, is drawn in liquid dispenser by admixing medical solutions, completes dosing.
A kind of radioprotective medicinal liquid subpackage based on above-mentioned radioprotective dosing, subpackage and injection device and injecting method, including with
Lower step:
S21, opens the valve between liquid dispenser and external interface, closes other valves, according to the fltting speed set,
Automatic or manual advances the push rod of liquid dispenser, and the medicinal liquid in liquid dispenser is sent into exterior line；
According to the signal of push rod position and limit switch, S22, judges whether subpackage or injection operation complete, after completing operation,
Close the valve between liquid dispenser and external interface.
After having operated, following S23-S24 is used to be carried out:
S23, opens the valve between liquid dispenser and normal saline bottle, controls liquid dispenser and extracts appropriate normal saline, then
Close this valve；
S24, opens the valve between liquid dispenser and external interface, the normal saline in injection liquid dispenser, completes pipeline
The cleaning of medicinal liquid.
During as it is shown in figure 9, select the push rod automatically advancing liquid dispenser, press hemostasis key, open liquid dispenser 25 with outside
Valve between interface, according to the speed set, liquid dispenser advances automatically, has injected when liquid dispenser arrives zero-bit；Choosing
When selecting the push rod manually advancing liquid dispenser, opening the valve between liquid dispenser 25 and external interface, manually advancing until joining
Liquid device zero-bit, injection completes.
Before subpackage or injection, advanced row pipeline-cleaning:
S31, opens the valve between liquid dispenser and normal saline bottle, controls liquid dispenser and extracts a certain amount of normal saline,
Make normal saline bottle pipeline is full of normal saline；Opening the valve between liquid dispenser and external interface, controlling liquid dispenser will
Valve is closed by exterior line after normal saline is all discharged in liquid dispenser；
S32, opens the valve between liquid dispenser and source liquid bottle, controls liquid dispenser and extracts a certain amount of source liquid, closes source liquid
Bottle pipe valve, opens waste liquid bottle pipe valve, controls liquid dispenser and is all discharged to give up by normal saline in liquid dispenser and source liquid
In liquid bottle, close waste liquid bottle pipe valve.
In sum, integration of the present invention solves the transfer of radioactive source liquid, subpackage and injection problem, can manually or
Automatically carry out subpackage and injection, all can change with all parts of medicament contact, ensured medicine without outside contamination, also
Ensure that medicine radiates without the external world, it also avoid the medicine pollution to machine simultaneously.
Claims (10)
1. radioprotective dosing, subpackage and an injection device, including dosing injecting unit, external interface (42) and anti-
Radiation shielded box, dosing injecting unit is arranged in radioprotective shielded box, it is characterised in that described dosing injecting unit bag
Include source liquid bottle (14), normal saline bottle (16), waste liquid bottle (17), measure bottle (4), for measurement bottle in real time
(4) activity meter (29) of inner liquid medicine activity, liquid dispenser (25), liquid dispenser linkage unit and controller；
The entrance of described liquid dispenser (25) by valve respectively with measure bottle (4), source liquid bottle (14) and normal saline bottle
(16) connect, the outlet of described liquid dispenser (25) by valve respectively with waste liquid bottle (17) and external interface (42)
Connect；
Described controller is used for receiving external command, determines source liquid measure and the saline volume needing extraction；Controller and work
Degree measuring instrument (29) communication, real-time measurement medicinal liquid activity, control liquid dispenser and control valve opening and closing, completing dosing, divide
Dress or injection；
Described liquid dispenser linkage unit is for receiving the signal that controller sends according to source liquid measure and saline volume, and driving is joined
Liquid device (25) extraction source liquid bottle (14) endogenous liquid and normal saline bottle (16) interior normal saline mix to measuring bottle (4)
Close, and carry out subpackage or injection by external interface (42)；
Described waste liquid bottle (17) is used for holding detergent line or unwanted surplus liquid.
Radioprotective dosing the most according to claim 1, subpackage and injection device, it is characterised in that described dosing
Device linkage unit includes liquid dispenser driving means (21) and position sensor (23), described liquid dispenser driving means (21)
For driving liquid dispenser (25) to carry out extraction；Described position sensor (23) is used for determining liquid dispenser (25) push rod
Displacement amount.
Radioprotective dosing the most according to claim 2, subpackage and injection device, it is characterised in that described dosing
Device linkage unit also includes that limit switch (30), described limit switch (30) are used for limiting liquid dispenser driving means (21)
Extreme position.
Radioprotective dosing the most according to claim 2, subpackage and injection device, it is characterised in that described dosing
Device driving means (21) includes internal hydraulic pressure push rod (26) and external hydraulic push rod, described internal hydraulic pressure push rod (26)
For driving liquid dispenser (25) to carry out extraction, described external hydraulic push rod coordinates with internal hydraulic pressure push rod (26), constitutes
Manual fluid body.
Radioprotective dosing the most according to claim 1, subpackage and injection device, it is characterised in that described valve
Including the first valve, the second valve, the 3rd valve, the 4th valve and the 5th valve, described first valve is arranged on dosing
Between device (25) and measurement bottle (4), described second valve is arranged between liquid dispenser (25) and source liquid bottle (14),
Described 3rd valve is arranged between liquid dispenser (25) and normal saline bottle (16), and described 4th valve is arranged on dosing
Between device (25) and waste liquid bottle (17), described 5th valve be arranged on liquid dispenser (25) and external interface (42) it
Between.
Radioprotective dosing the most according to claim 5, subpackage and injection device, it is characterised in that described first
Valve, the second valve, the 3rd valve, the 4th valve and the 5th valve equal break-make type valve.
Radioprotective dosing the most according to claim 1, subpackage and injection device, it is characterised in that radioprotective every
Casing, case lid (11) and stepper assemblies is included from case；Described stepper assemblies is used for receiving controller instruction,
Control case lid (11) opening and closing.
Radioprotective dosing the most according to claim 1, subpackage and injection device, it is characterised in that described outside
Interface (42) connects exterior tube joint (19), and exterior tube joint (19) is provided with check valve (15).
Radioprotective dosing the most according to claim 1, subpackage and injection device, it is characterised in that device also wraps
Including display unit and operation button, described display unit shows solution volume in liquid dispenser in real time；Described operation button includes
Function menu button, system switching button and cover switch button, for controller send instruction realize automatic liquid matching,
Automatic subpackaging or injection, system switching and case lid opening and closing.
10. a radioprotective dosing, subpackage and injecting method, it is characterised in that use the anti-spoke described in claim 1
Penetrate dosing, subpackage and injection device, comprise the following steps:
Determine the medicinal liquid activity needing to use according to formula, and determine source liquid measure and the saline volume of needs；
Opening the valve between liquid dispenser and source liquid bottle, control the quantitative source liquid of liquid dispenser extraction and enter measurement bottle, activity is surveyed
Activity in bottle measured in real time by amount instrument, and controls to enter the source liquid measure in bottle；
Close the valve between liquid dispenser and source liquid bottle, open the valve between liquid dispenser and normal saline bottle, according to formula
Extract quantitative saline volume, and be injected in measurement bottle and mix, after completing, close valve；
Open the valve measured between bottle and liquid dispenser, admixing medical solutions is drawn in liquid dispenser, completes dosing；
Open the valve between liquid dispenser and external interface, close other valves, according to the fltting speed set, automatically or
Manually advance the push rod of liquid dispenser, the medicinal liquid in liquid dispenser is delivered to external interface, complete subpackage or injection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610252433.5A CN105853221A (en) | 2016-04-21 | 2016-04-21 | Anti-radiation dosing, split-charging and injection device and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610252433.5A CN105853221A (en) | 2016-04-21 | 2016-04-21 | Anti-radiation dosing, split-charging and injection device and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105853221A true CN105853221A (en) | 2016-08-17 |
Family
ID=56633527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610252433.5A Pending CN105853221A (en) | 2016-04-21 | 2016-04-21 | Anti-radiation dosing, split-charging and injection device and method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105853221A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107050658A (en) * | 2017-04-17 | 2017-08-18 | 宁波中哲医疗科技有限公司 | A kind of automatic more exchange device of carbon-point |
| CN108159907A (en) * | 2018-01-04 | 2018-06-15 | 四川汉辉盛世医疗科技有限公司 | A kind of liquid mixing system and method |
| CN108686296A (en) * | 2017-04-07 | 2018-10-23 | 华克医疗科技（北京）股份公司 | Radiopharmaceutical automated injection device |
| CN109761181A (en) * | 2019-01-07 | 2019-05-17 | 森科（南京）医药技术有限公司 | Full-automatic sodium iodide oral liquor medicine nucleic dispenses instrument |
| CN112194086A (en) * | 2020-09-24 | 2021-01-08 | 昆明医科大学第二附属医院 | Radionuclide partial shipment system |
| CN113350177A (en) * | 2021-07-08 | 2021-09-07 | 天津中核永泰科技有限公司 | Auxiliary nuclide semi-automatic injection device |
| CN113619827A (en) * | 2021-10-11 | 2021-11-09 | 依贝伽射线防护设备科技(江苏)有限公司 | Radiopharmaceutical nonradiative intelligence partial shipment device that declines |
| CN113926023A (en) * | 2021-08-30 | 2022-01-14 | 上海盛榕医疗器械科技有限公司 | Integrated full-automatic nuclide split charging injection device and method |
| CN114159690A (en) * | 2021-12-16 | 2022-03-11 | 中日友好医院(中日友好临床医学研究所) | Extremely simple whole-course unmanned nuclear medicine split charging and injection integrated machine |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2840273Y (en) * | 2005-08-24 | 2006-11-22 | 重庆帝格科技发展有限公司 | Radioactive isotope and reagent automatic subpackaging instrument |
| CN101108718A (en) * | 2007-08-16 | 2008-01-23 | 山东省立医院 | Automatic dilution split charging instrument of radionuclide liquid medicine and dilution split charging method thereof |
| CN103203070A (en) * | 2012-01-16 | 2013-07-17 | 住友重机械工业株式会社 | Radioactive liquid delivery device and method of detecting bad states thereof |
| CN203217960U (en) * | 2013-05-06 | 2013-09-25 | 余巧生 | Radionuclide split-charging protective cabinet |
| CN203938455U (en) * | 2014-06-30 | 2014-11-12 | 张式琦 | The Special Automatic packing instrument of a kind of nucleic |
| KR20150010285A (en) * | 2013-07-19 | 2015-01-28 | (주)유니테코 | Radio-pharmaceuticals dispensing apparatus with radiation dosage measuring part |
| CN204159235U (en) * | 2014-10-08 | 2015-02-18 | 杭州中旺科技有限公司 | A kind of automatic liquid dispenser |
| CN204910478U (en) * | 2015-07-15 | 2015-12-30 | 福建希飞医药科技有限公司 | Automatic infusion device of PET -CT radiopharmaceutical |
| CN105288835A (en) * | 2015-10-20 | 2016-02-03 | 巴建涛 | Automatic subpackaging and injecting system for radiopharmaceuticals |
-
2016
- 2016-04-21 CN CN201610252433.5A patent/CN105853221A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2840273Y (en) * | 2005-08-24 | 2006-11-22 | 重庆帝格科技发展有限公司 | Radioactive isotope and reagent automatic subpackaging instrument |
| CN101108718A (en) * | 2007-08-16 | 2008-01-23 | 山东省立医院 | Automatic dilution split charging instrument of radionuclide liquid medicine and dilution split charging method thereof |
| CN103203070A (en) * | 2012-01-16 | 2013-07-17 | 住友重机械工业株式会社 | Radioactive liquid delivery device and method of detecting bad states thereof |
| CN203217960U (en) * | 2013-05-06 | 2013-09-25 | 余巧生 | Radionuclide split-charging protective cabinet |
| KR20150010285A (en) * | 2013-07-19 | 2015-01-28 | (주)유니테코 | Radio-pharmaceuticals dispensing apparatus with radiation dosage measuring part |
| CN203938455U (en) * | 2014-06-30 | 2014-11-12 | 张式琦 | The Special Automatic packing instrument of a kind of nucleic |
| CN204159235U (en) * | 2014-10-08 | 2015-02-18 | 杭州中旺科技有限公司 | A kind of automatic liquid dispenser |
| CN204910478U (en) * | 2015-07-15 | 2015-12-30 | 福建希飞医药科技有限公司 | Automatic infusion device of PET -CT radiopharmaceutical |
| CN105288835A (en) * | 2015-10-20 | 2016-02-03 | 巴建涛 | Automatic subpackaging and injecting system for radiopharmaceuticals |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108686296A (en) * | 2017-04-07 | 2018-10-23 | 华克医疗科技（北京）股份公司 | Radiopharmaceutical automated injection device |
| CN107050658A (en) * | 2017-04-17 | 2017-08-18 | 宁波中哲医疗科技有限公司 | A kind of automatic more exchange device of carbon-point |
| CN107050658B (en) * | 2017-04-17 | 2023-07-25 | 宁波中哲医疗科技有限公司 | Automatic replacement equipment for carbon rod |
| CN108159907A (en) * | 2018-01-04 | 2018-06-15 | 四川汉辉盛世医疗科技有限公司 | A kind of liquid mixing system and method |
| CN108159907B (en) * | 2018-01-04 | 2023-08-29 | 四川汉辉盛世医疗科技有限公司 | Liquid mixing system and method |
| CN109761181A (en) * | 2019-01-07 | 2019-05-17 | 森科（南京）医药技术有限公司 | Full-automatic sodium iodide oral liquor medicine nucleic dispenses instrument |
| CN112194086A (en) * | 2020-09-24 | 2021-01-08 | 昆明医科大学第二附属医院 | Radionuclide partial shipment system |
| CN113350177A (en) * | 2021-07-08 | 2021-09-07 | 天津中核永泰科技有限公司 | Auxiliary nuclide semi-automatic injection device |
| CN113926023A (en) * | 2021-08-30 | 2022-01-14 | 上海盛榕医疗器械科技有限公司 | Integrated full-automatic nuclide split charging injection device and method |
| CN113619827A (en) * | 2021-10-11 | 2021-11-09 | 依贝伽射线防护设备科技(江苏)有限公司 | Radiopharmaceutical nonradiative intelligence partial shipment device that declines |
| CN113619827B (en) * | 2021-10-11 | 2021-12-07 | 依贝伽射线防护设备科技(江苏)有限公司 | Radiopharmaceutical nonradiative intelligence partial shipment device that declines |
| CN114159690A (en) * | 2021-12-16 | 2022-03-11 | 中日友好医院(中日友好临床医学研究所) | Extremely simple whole-course unmanned nuclear medicine split charging and injection integrated machine |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105853221A (en) | Anti-radiation dosing, split-charging and injection device and method | |
| CN101516420B (en) | Medical unit for the collection, calibration, dilution and/or injection of an injectable radioactive product | |
| US7712491B2 (en) | Process and device for the dose dispensing of a radioactive solution | |
| JP5052186B2 (en) | Radiopharmaceutical automatic administration apparatus and method for administering radiopharmaceutical using the apparatus | |
| CN104784770B (en) | The infusion system safeguarded and/or operated including area of computer aided | |
| CN102774801B (en) | Automatic radioactive medicament split charging injector and automatic radioactive medicament split charging method | |
| JP2006043417A (en) | Dispensing and injection system for radiopharmaceuticals | |
| US20080260580A1 (en) | Method and System for Radiopharmaceutical Kit Preparation | |
| KR20090101450A (en) | System for dispensing radio-pharmaceuticals and measuring radiation dosage of it | |
| AU2013271796A1 (en) | Radiopharmaceutical delivery and tube management system | |
| ITUD20070093A1 (en) | EQUIPMENT FOR THE AUTOMATIC PREPARATION OF A DRUG AND ITS PROCEDURE FOR PREPARATION | |
| CN112666293A (en) | Liquid phase automatic synthesizer | |
| CN103203070A (en) | Radioactive liquid delivery device and method of detecting bad states thereof | |
| JP5228181B2 (en) | Radiopharmaceutical automatic administration device | |
| CN216877582U (en) | Automatic injection device for radioactive liquid medicine | |
| CN108686296A (en) | Radiopharmaceutical automated injection device | |
| WO2009128045A2 (en) | Apparatus and method for preparing medicines containing radioactive substances | |
| CN207837872U (en) | A kind of remaining medicine draw-out device | |
| CN106379734A (en) | Automatic subpackaging equipment and method | |
| CN217025280U (en) | Multi-channel nuclide automatic split charging instrument | |
| CN114134027B (en) | Portable fast detector for new coronavirus | |
| CN115040770A (en) | Radiopharmaceutical injection device, full-automatic injection vehicle and injection method | |
| CN211068739U (en) | Radioactive suspension medicine infusion system | |
| CN2905751Y (en) | Automatic split-packing instrument for radioactive nuclide liquor | |
| CN216378205U (en) | Portable rapid new coronavirus detector and nucleic acid detection medium controller |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160817 |