CN108159907B - Liquid mixing system and method - Google Patents
Liquid mixing system and method Download PDFInfo
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- CN108159907B CN108159907B CN201810006784.7A CN201810006784A CN108159907B CN 108159907 B CN108159907 B CN 108159907B CN 201810006784 A CN201810006784 A CN 201810006784A CN 108159907 B CN108159907 B CN 108159907B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/45—Mixing liquids with liquids; Emulsifying using flow mixing
- B01F23/451—Mixing liquids with liquids; Emulsifying using flow mixing by injecting one liquid into another
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/405—Methods of mixing liquids with liquids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/712—Feed mechanisms for feeding fluids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/7176—Feed mechanisms characterised by the means for feeding the components to the mixer using pumps
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention provides a liquid mixing system and a liquid mixing method, wherein the liquid mixing system comprises a first pump (9), a second pump (13) and a contact pin (26), the contact pin (26) comprises a fixed plate (268), a liquid inlet pipe (261) and a liquid outlet pipe (262) are arranged on the fixed plate (268), the inlet end of the liquid inlet pipe (261) is communicated with a first liquid supply pipe (27), the first pump (9) is arranged on the first liquid supply pipe (27), the outlet end of the liquid outlet pipe (262) is communicated with a second liquid suction pipe (20), and the second pump (13) is arranged on the second liquid suction pipe (20). The first liquid supply pipe is connected and communicated with the liquid supply bottle, the second liquid suction pipe is connected and communicated with the dilution bottle, the stock solution bottle containing stock solution is placed below the contact pin, the stock solution is injected into the liquid supply bottle to be mixed, the second pump and the first pump are started, and liquid mixing can be completed in the dilution bottle without direct contact of operators with mixed liquid.
Description
Technical Field
The invention relates to the technical field of liquid mixing, in particular to a liquid mixing system and a liquid mixing method for taking and diluting corrosive, radioactive and other stock solutions.
Background
In the medical industry or in chemical industry, etc., it is often necessary to perform a liquid compounding operation, i.e., to mix different types of liquids. Because the mixed liquid can be corrosive or radioactive, particularly for radiotherapy and chemotherapy treatment in the medical industry, nuclide stock solution is needed. The nuclide stock solution has certain radioactivity, has higher operation requirements on medical staff in the operations of liquid taking, dilution, liquid pumping and the like, also easily causes potential safety hazards such as nuclear radiation and the like of the medical staff, and has inconvenient operation and low liquid preparation operation efficiency. In addition, in the conventional liquid mixing operation, a belt type or track type transmission mode is generally adopted for the transmission of the mixed stock solution, and the transmission mode has larger limitation on the appearance volume of equipment, and when a plurality of objects are transmitted, the volume of the whole operation system can be greatly increased, and the operation is very inconvenient.
Disclosure of Invention
The invention aims to solve the technical problems that: aiming at the problems in the prior art, the liquid mixing system and the liquid mixing method are provided, and the safety and the efficiency of liquid mixing operation are improved.
The technical problems to be solved by the invention are realized by adopting the following technical scheme: the utility model provides a liquid blending system, includes first pump, second pump and contact pin, the contact pin includes the fixed plate, sets up feed liquor pipe and the drain pipe that link up the fixed plate on the fixed plate, feed liquor pipe entrance point and first feed liquor pipe are connected and are communicated, set up first pump on first feed liquor pipe, the drain pipe exit end is connected and is communicated with second drawing liquid pipe, sets up the second pump on the second drawing liquid pipe.
Preferably, the rotary table further comprises a feeding and conveying mechanism, wherein the feeding and conveying mechanism comprises a rotary table, a rotary shaft and a rotary table driving motor, a limiting sinking groove is formed in the rotary table, a fixed connection is formed between the rotary shaft and the rotary table, a mutually perpendicular structure is formed between the rotary shaft and the limiting sinking groove, and the rotary table driving motor drives the rotary shaft to do rotary motion.
Preferably, the contact pin is fixedly connected with the lifting mechanism through the fixing plate, and the lifting mechanism controls the contact pin to move up and down in a straight line.
Preferably, the lifting mechanism comprises a frame, a screw rod, a sliding block and a stepping motor, wherein the screw rod is arranged on the frame, the screw rod and the sliding block are in threaded movable connection, and the sliding block is fixedly connected with the fixed plate; the stepping motor drives the lead screw to rotate relative to the frame, and the sliding block drives the contact pin to move up and down linearly relative to the lead screw.
Preferably, the device also comprises a dilution bottle and a second liquid supply pipe, wherein the opposite ends of the second liquid supply pipe are respectively communicated with the dilution bottle and the first liquid supply pipe.
Preferably, the dilution bottle is of a hollow cavity structure, the first pipeline interface and the third pipeline interface are respectively and fixedly connected to the two opposite ends of the dilution bottle, the first pipeline interface and the third pipeline interface are communicated with the hollow cavity of the dilution bottle, a flow guiding structure is arranged at the bottom of the hollow cavity of the dilution bottle, and the lowest point of the flow guiding structure is communicated with the third pipeline interface.
Preferably, the device further comprises an analysis bottle, wherein the analysis bottle is connected and communicated with the dilution bottle through a first liquid suction pipe, and a fourth pump is arranged on the first liquid suction pipe.
Preferably, the analysis bottle is of a hollow cavity structure, the two opposite ends of the analysis bottle are respectively and fixedly connected with a liquid inlet pipeline interface and a liquid outlet pipeline interface, the liquid inlet pipeline interface and the liquid outlet pipeline interface are communicated with the hollow inner cavity of the analysis bottle, a drainage structure is arranged at the bottom of the hollow inner cavity of the analysis bottle, and the lowest point of the drainage structure is communicated with the liquid outlet pipeline interface.
Preferably, the liquid taking device further comprises a liquid taking bottle, wherein the liquid taking bottle is communicated with the dilution bottle through a liquid taking pipe, and a third pump is arranged on the liquid taking pipe.
A liquid compounding method, which is carried out by adopting the liquid compounding system, and comprises the following steps:
s1, connecting and communicating a first liquid supply pipe with a liquid supply bottle, connecting and communicating a second liquid suction pipe with a dilution bottle, placing a stock solution bottle containing stock solution below a contact pin, and injecting the stock solution into the liquid supply bottle;
s2, enabling the bottom of the contact pin to be inserted into the inner cavity of the stock solution bottle, starting the second pump, extracting stock solution from the stock solution bottle into the dilution bottle, starting the first pump, and extracting the liquid from the liquid supply bottle into the dilution bottle.
Compared with the prior art, the invention has the beneficial effects that: when the liquid mixing operation is carried out, only the first liquid supply pipe is connected and communicated with the liquid supply bottle, the second liquid suction pipe is connected and communicated with the dilution bottle, the raw liquid bottle containing the raw liquid is placed below the contact pin, the raw liquid is injected into the liquid supply bottle to be mixed, when the bottom of the contact pin is inserted into the inner cavity of the raw liquid bottle, the second pump is started, the raw liquid can be extracted from the raw liquid bottle into the dilution bottle, the first pump is started, the mixed liquid can be extracted from the liquid supply bottle into the dilution bottle, finally the liquid mixing is completed in the dilution bottle, the operation personnel does not need to directly contact the mixed liquid, the potential safety hazard caused by liquid pollution is avoided, and therefore the liquid mixing operation safety and the liquid mixing operation efficiency are improved.
Drawings
Fig. 1 is a schematic view (three-dimensional view) of a liquid compounding system according to the present invention.
Fig. 2 is a front view of the liquid compounding system shown in fig. 1.
Fig. 3 is a top view of the liquid compounding system shown in fig. 1.
Fig. 4 is a schematic view of the elevating mechanism in fig. 1.
Fig. 5 is a front view of the dilution bottle.
Fig. 6 is a top view of the dilution bottle.
Fig. 7 is a three-dimensional view of an analysis bottle.
Fig. 8 is a front view of an analysis bottle.
Fig. 9 is a front view of the turntable.
Fig. 10 is a top view of the turntable.
Fig. 11 is a side view of the turntable.
Fig. 12 is a front view of a pin.
Fig. 13 is a top view of a pin.
Fig. 14 is a side view of a pin.
Fig. 15 is a schematic diagram of the liquid path principle of the liquid compounding system shown in fig. 1.
The marks in the figure: 1-liquid supply bottle, 2-outer shell, 3-base, 4-dilution bottle, 5-first drawing tube, 6-ionization chamber, 7-analysis bottle, 8-liquid taking tube, 9-first pump, 10-liquid taking bottle, 11-controller, 12-liquid distribution analyzer, 13-second pump, 14-recovery tube, 15-third pump, 16-recovery bottle, 17-fourth pump, 18-position detection sensor, 19-lifting mechanism, 20-second drawing tube, 21-turntable, 22-manipulator, 23-sealing cover, 24-rotating shaft, 25-raw liquid bottle, 26-contact pin, 27-first liquid supply tube, 28-second liquid supply tube, 29-two-position three-way electromagnetic valve, 41-first pipeline interface, 42-second pipeline interface, 43-exhaust port, 44-third pipeline interface, 45-diversion structure, 71-liquid inlet pipeline interface, 72-liquid outlet pipeline interface, 73-arc structure transition part, 74-diversion structure, 191-lead screw, 192-stepping motor, 193-slide block, 194-guide rod, 195-frame, 211-spacing sink, 212-shaft positioning hole, 261-liquid inlet pipe, 262-liquid outlet pipe, 263-exhaust pipe, 264-mounting hole, 265-liquid inlet pipe outlet, 266-liquid outlet pipe inlet, 267-exhaust pipe inlet, 268-fixed plate.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in detail with reference to the accompanying drawings and specific embodiments. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
The liquid mixing system as shown in fig. 1, 2, 3 and 15 mainly comprises a liquid supply bottle 1, a base 3, a dilution bottle 4, an analysis bottle 7, a recovery bottle 16, a stock solution bottle 25 and a contact pin 26, wherein the dilution bottle 4 is of a hollow cavity structure as shown in fig. 5 and 6, a first pipeline interface 41 and a third pipeline interface 44 are fixedly connected to opposite ends of the dilution bottle 4 respectively, and the first pipeline interface 41 and the third pipeline interface 44 are communicated with a hollow cavity of the dilution bottle 4. Preferably, the first pipeline connector 41, the third pipeline connector 44 and the dilution bottle 4 are integrally formed. A flow guiding structure 45 is arranged at the bottom of the hollow inner cavity of the dilution bottle 4, the flow guiding structure 45 is preferably an inner spherical groove, and the lowest point of the flow guiding structure is communicated with the third pipeline interface 44. The flow guiding structure 45 may also be a groove formed by a wedge-shaped surface, and the lowest point of the groove is communicated with the third pipeline interface 44. Preferably, the wedge-shaped surfaces in the flow guiding structure 45 have an inclination of 5 ° -9 °, such as 6 °,7 ° or 8 °. Preferably, the flow guiding structure 45 can also be designed as a conical structure groove, the opening angle of which is preferably 165 ° -170 °. By adopting the structural design, the liquid in the dilution bottle 4 can be discharged cleanly to the greatest extent, and the concentration of the next preparation is avoided, so that the dilution bottle 4 can be well ensured not to cause mutual interference of the preparations in repeated use.
A second line connection 42 and an exhaust port 43 are also fixedly connected to the dilution bottle 4. Preferably, the second pipe connector 42, the air outlet 43 and the dilution bottle 4 are integrally formed. The second pipeline connector 42 is positioned at the same end of the dilution bottle 4 as the first pipeline connector 41 and is communicated with the hollow cavity of the dilution bottle 4. The exhaust port 43 and the first pipeline connector 41 are positioned at the same end of the dilution bottle 4 and are communicated with the hollow cavity of the dilution bottle 4. Preferably, the first pipe connector 41 and the second pipe connector 42 have a convex cone structure, so as to facilitate the connection of the liquid pipe and ensure the sealing reliability of the pipe connection.
The analysis bottle 7 has a hollow cavity structure as shown in fig. 7 and 8, and two opposite ends of the analysis bottle 7 are respectively and fixedly connected with a liquid inlet pipeline interface 71 and a liquid outlet pipeline interface 72. Preferably, the liquid inlet pipeline interface 71, the liquid outlet pipeline interface 72 and the analysis bottle 7 are integrally formed. In order to ensure the integral forming quality of the analysis bottle 7 and improve the mechanical connection strength of the liquid inlet pipeline interface 71 and the liquid outlet pipeline interface 72, the connection part between the liquid inlet pipeline interface 71 and the analysis bottle 7 forms an arc structure transition part 73; similarly, the connection between the outlet line connection 72 and the analysis bottle 7 forms a transition 73 of circular arc structure.
The hollow cavity of the analysis bottle 7 is a cylindrical cavity, and the ratio of the inner diameters of the liquid inlet pipeline interface 71 and the liquid outlet pipeline interface 72 to the inner diameter of the hollow cavity of the analysis bottle 7 is 1:20-1:10; preferably, the ratio of the inner diameters of the liquid inlet pipeline interface 71 and the liquid outlet pipeline interface 72 to the inner diameter of the hollow cavity of the analysis bottle 7 is 1.5:20. the liquid inlet pipeline interface 71 and the liquid outlet pipeline interface 72 are communicated with the hollow inner cavity of the analysis bottle 7, and a drainage structure 74 is arranged at the bottom of the hollow inner cavity of the analysis bottle 7. The drainage structure 74 may be configured as an internal spherical groove, and its lowest point is in communication with the outlet pipe connection 72. Alternatively, the drainage structures 74 may be grooves formed by wedge faces having an inclination angle of preferably 5 ° -9 °, such as 6 °,7 °, or 8 °. Alternatively, the drainage structures 74 may be designed as conical structure grooves, preferably with an opening angle of 165 ° -170 °. By adopting the structural design, the liquid in the analysis bottle 7 can be discharged cleanly to the greatest extent, and the mutual interference of the analysis liquid caused by repeated use of the analysis bottle 7 is avoided. Further, the liquid inlet pipe interface 71 and the liquid outlet pipe interface 72 on the analysis bottle 7 adopt a convex cone structure, preferably, the taper of the liquid inlet pipe interface 71 and the liquid outlet pipe interface 72 is set to 28-35 degrees, so as to facilitate the connection of liquid pipes and ensure the sealing reliability of the pipe connection.
In order to facilitate the continuous operation of the liquid mixing system, the manual operation is reduced, the liquid mixing working efficiency is improved, and a feeding transmission mechanism and a liquid extraction mechanism can be additionally arranged in the liquid mixing system. The feeding transmission mechanism comprises a rotary table 21, a rotary shaft 24 and a rotary table driving motor, the specific structure of the rotary table 21 is shown in fig. 9, 10 and 11, a limiting sink 211 and a shaft positioning hole 212 are formed in the rotary table 21, and the limiting sink 211 is preferably a cylindrical sink. The rotating shaft 24 penetrates through the shaft positioning hole 212 and is fixedly connected with the rotating disc 21, a mutually perpendicular structure is formed between the rotating shaft 24 and the limiting sink 211, and the rotating disc driving motor drives the rotating shaft 24 to rotate, so that the rotating shaft 24 drives the rotating disc 21 to rotate. The turntable driving motor is connected with a speed reducer to drive the rotating shaft 24 to rotate through the speed reducer. Preferably, a plurality of limiting sink grooves 211 on the turntable 21 may be provided, and the ring-equalizing shafts 24 are distributed. Further, the limiting sink slots 211 are uniformly distributed around the rotating shaft 24. The turntable 21 may be further provided with a position detection sensor 18, the turntable driving motor may be a stepping motor, the speed reducer and the position detection sensor 18 are respectively electrically connected with the controller 11, and the controller 11 preferably adopts a PLC. Through the centralized control of the PLC, manual operation can be saved, and the feeding accuracy of the turntable 21 is improved, so that the automatic operation of the liquid mixing system is conveniently realized.
The liquid extraction mechanism includes a contact pin 26 and a lifting mechanism 19, the specific structure of the contact pin 26 is as shown in fig. 12, 13 and 14, and mainly includes a liquid inlet pipe 261, a liquid outlet pipe 262, an exhaust pipe 263 and a fixing plate 268, a pipe through hole and a mounting hole 264 are formed in the fixing plate 268, the liquid inlet pipe 261, the liquid outlet pipe 262 and the exhaust pipe 263 penetrate through the pipe through hole in the fixing plate 268, and the liquid inlet pipe 261, the liquid outlet pipe 262 and the exhaust pipe 263 are fixedly connected with the fixing plate 268 into a whole by using sealant, and a sealing structure is formed at the interconnection part. Preferably, the end of the inlet pipe 261 forms a wedge-shaped inlet pipe outlet 265, the end of the outlet pipe 262 also forms a wedge-shaped outlet pipe inlet 266, and the end of the outlet pipe 263 also forms a wedge-shaped outlet pipe inlet 267. Further, the inclination angle of the inlet pipe outlet 265, the inclination angle of the outlet pipe inlet 266, and the inclination angle of the exhaust pipe inlet 267 are respectively set to 30 ° -45 °. By adopting the structural design, the puncture operation of the contact pin 26 can be facilitated, the puncture resistance is reduced, and the pipeline blockage of the liquid inlet pipe 261, the liquid outlet pipe 262 and the exhaust pipe 263 in the puncture operation is effectively prevented.
As shown in fig. 4, the lifting mechanism 19 mainly comprises a screw rod 191, a guide rod 194, a frame 195, a slide block 193 and a stepping motor 192, wherein the screw rod 191 is mounted on the frame 195, the screw rod 191 and the slide block 193 form a threaded movable connection, the guide rod 194 is fixedly connected with the frame 195, and the slide block 193 and the guide rod 194 form a movable connection capable of sliding relatively linearly. The stepper motor 192 drives the screw rod 191 to rotate relative to the frame 195, and the slider 193 moves linearly up and down relative to the screw rod 191, wherein the guide rod 194 can enhance the mechanical strength of the frame 195, and can ensure the stability of the vertical linear movement of the slider 193 relative to the screw rod 191.
When the liquid mixing system is adopted for liquid mixing operation, the operation steps are as follows:
first, according to the assembled liquid mixing system as shown in fig. 1 and 15, the pins 26 are fixedly connected to the lifting mechanism 19 through the fixing plates 268, and the lifting mechanism 19 controls the pins 26 to move vertically and linearly. Specifically, the fixing plate 268 and the slider 193 are fixedly connected by penetrating the mounting hole 264 through a connecting bolt, so that the slider 193 drives the contact pin 26 to move up and down linearly relative to the screw 191. The inlet end of the liquid inlet pipe 261 is connected and communicated with the liquid supply bottle 1 through a first liquid supply pipe 27, a first pump 9 is arranged on the first liquid supply pipe 27, the outlet end of the liquid outlet pipe 262 is connected and communicated with a first pipeline interface 41 on the dilution bottle 4 through a second liquid suction pipe 20, and a second pump 13 is arranged on the second liquid suction pipe 20. The liquid inlet pipeline interface 71 on the analysis bottle 7 is communicated with the third pipeline interface 44 on the dilution bottle 4 through the first liquid suction pipe 5, and the fourth pump 17 is arranged on the first liquid suction pipe 5. The liquid taking bottle 10 is connected and communicated with the dilution bottle 4 through a liquid taking pipe 8, and a third pump 15 is arranged on the liquid taking pipe 8. The recovery bottle 16 is communicated with the dilution bottle 4 through a recovery pipe 14, and the recovery pipe 14 is communicated with the liquid taking pipe 8.
Then, a stock solution bottle 25 containing stock solution is placed under the pin 26, and the stock solution is poured into the liquid supply bottle 1.
Next, the contact pin 26 is controlled to move linearly downwards through the lifting mechanism 19 until the bottoms of the liquid inlet pipe 261 and the liquid outlet pipe 262 on the contact pin 26 are inserted into the inner cavity of the stock solution bottle 25, the first pump 9 is started, and liquid preparation is injected into the inner cavity of the stock solution bottle 25 through the first liquid supply pipe 27 and the liquid inlet pipe 261, and the liquid preparation and the stock solution are mixed in the stock solution bottle 25; simultaneously, the second pump 13 is started, and a certain amount of mixed liquid can be pumped from the stock solution bottle 25 through the liquid outlet pipe 262 and the second liquid suction pipe 20 and injected into the dilution bottle 4. In order to increase the preparation speed of the liquid in the dilution bottle 4 and further increase the mixing operation efficiency, a second liquid supply pipe 28 may be additionally provided, an outlet end of the second liquid supply pipe 28 is connected and communicated with a second pipeline interface 42 on the dilution bottle 4, and an inlet end of the second liquid supply pipe 28 is connected and communicated with the first liquid supply pipe 27, so that after the first pump 9 is started, the liquid can be injected into the stock solution bottle 25 through the first liquid supply pipe 27 and the liquid inlet pipe 261, and meanwhile, the liquid can be injected into the dilution bottle 4 through the first liquid supply pipe 27 and the second liquid supply pipe 28.
Finally, the third pump 15 is started, and a certain amount of mixed liquid can be pumped from the dilution bottle 4 through the liquid taking pipe 8 and injected into the liquid taking bottle 10. The fourth pump 17 is activated to draw a certain amount of the compound from the dilution bottle 4 through the first draw tube 5 and to inject the compound into the analysis bottle 7.
As shown in fig. 1, since the stock solution bottle 25 containing the stock solution such as corrosiveness and radioactivity is sealed by the seal cover 23, there is a certain safety hazard to the field operators in the operations of taking, diluting, analyzing, extracting and the like the stock solution such as corrosiveness and radioactivity. In order to protect the personal safety of operators, the liquid mixing system can be arranged in the outer shell 2, and the outer shell 2 is preferably a sealed box body made of corrosion-resistant and radiation-resistant materials. 2 sets of independent lifting mechanisms 19 are fixedly arranged on the base 3, wherein a sliding block 193 on one set of lifting mechanism 19 is fixedly connected with a fixed plate 268 on the contact pin 26 so as to control the contact pin 26 to move up and down linearly; the other set of lifting mechanism 19 is fixedly connected with the manipulator 22, specifically, a sliding block 193 in the lifting mechanism 19 is fixedly connected with the manipulator 22, so that the manipulator 22 is driven to move up and down linearly relative to the screw rod 191 through the sliding block 193. The stepping motors 192 in the lifting mechanism 19 are electrically connected with the controller 11, and the stepping motors 192 drive the screw rods 191 to perform rotary motion relative to the frame 195.
As shown in fig. 1 and 15, the base 3 is further provided with an ionization chamber 6, a liquid distribution analyzer 12 and a position detection sensor 18, the turntable 21 is also provided with the position detection sensor 18, the ionization chamber 6 is provided with an analysis bottle 7, and the analysis liquid in the analysis bottle 7 flows out of the ionization chamber 6 through a liquid outlet pipeline interface 72, and is correspondingly analyzed by the liquid distribution analyzer 12. The liquid taking pipe 8 is internally provided with a two-position three-way electromagnetic valve 29, and the two-position three-way electromagnetic valve 29 is connected and communicated with the recovery pipe 14. The first liquid supply pipe 27 is also provided with a two-position three-way electromagnetic valve 29, and the opposite ends of the second liquid supply pipe 28 are respectively connected and communicated with the dilution bottle 4 and the two-position three-way electromagnetic valve 29. The first pump 9, the liquid distribution analyzer 12, the second pump 13, the third pump 15, the fourth pump 17, the position detection sensor 18, the manipulator 22, the two-position three-way electromagnetic valve 29 and the stepping motor 192 are respectively and electrically connected with the controller 11. The turntable driving motor also adopts a stepping motor and is electrically connected with the controller 11. The controller 11 is electrically connected with the liquid distribution upper computer to form an intelligent liquid distribution system, and the intelligent liquid distribution operation can be realized by sending corresponding liquid distribution instructions through the liquid distribution upper computer. The specific operation steps are as follows:
s1, placing stock solution bottles 25 on a turntable 21, wherein each stock solution bottle 25 is placed, and the controller 11 sends a pulse signal to control the turntable 21 to rotate once; in this embodiment, a total of 4 stock solution bottles 25 can be placed. The controller 11 determines the position of the stock solution bottle 25 on the turntable 21 according to the feedback signal of the position detection sensor 18, and further controls the turntable 21 to rotate to a specified position.
S2, the liquid distribution upper computer sends a liquid distribution instruction to the controller 11, so that the manipulator 22 starts to work. According to the position signal of the turntable 21 fed back by the position detection sensor 18, the controller 11 controls the manipulator 22 to move up and down in a straight line until the manipulator 22 is adjusted to a proper position and grabs the sealing cover 23; after the manipulator 22 grabs the sealing cover 23, the manipulator moves upwards and keeps clamping the sealing cover 23 until the stock solution bottle 25 is completely opened.
S3, the controller 11 sends out a liquid pumping instruction, the rotary table 21 rotates to a position below the contact pin 26, the controller 11 controls the contact pin 26 to descend to the position, the second pump 13 is started to start pumping the stock solution from the stock solution bottle 25 to the dilution bottle 4, and meanwhile, the first pump 9 is started to start pumping the liquid from the liquid supply bottle 1 to the dilution bottle 4. When the liquid in the stock solution bottle 25 on the turntable 21 is used up, the controller 11 controls the turntable 21 to rotate reversely to a specified position, and the manipulator 22 places the sealing cover 23 on the stock solution bottle 25. The position detecting sensor 18 again detects the remaining unused stock solution bottles 25 on the turntable 21, and the above operation is again circulated until the stock solution bottles 25 on the turntable 21 are completely used.
And S4, after the mixed liquid in the dilution bottle 4 is diluted, the controller 11 sends out a liquid pumping instruction, the fourth pump 17 is started, the mixed liquid in the dilution bottle 4 is pumped into the analysis bottle 7, the corresponding analysis is carried out by the liquid distribution analyzer 12, and the analysis result is fed back to the controller 11.
S5, the controller 11 automatically calculates the required liquid taking amount according to the received analysis data; according to the liquid taking amount, the controller 11 sends out a liquid taking instruction, the third pump 15 is started, and a certain amount of mixed liquid is pumped from the dilution bottle 4 to the liquid taking bottle 10; meanwhile, the information such as the dilution concentration, the liquid consumption, the residual quantity of the stock solution and the like is automatically recorded by the liquid distribution upper computer system and enters a database.
And S6, after the mixed liquid in the dilution bottle 4 is extracted, the controller 11 sends out a cleaning instruction, the cleaning liquid output by the liquid supply bottle 1 cleans the stock solution through a pipeline, and the cleaned cleaning liquid is finally extracted into the recovery bottle 16 by the third pump 15.
It should be noted that, because the turntable 21 can be filled with a plurality of stock solution bottles 25 at a time, the rotation of the positioning and fixing points of the turntable 21 can be realized by controlling the controller 11, and compared with the traditional belt type or track type feeding and conveying mode, the feeding and conveying mode is convenient to operate and has small influence on the whole appearance volume of the equipment.
The foregoing description of the preferred embodiment of the invention is not intended to be limiting, but rather to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the invention.
Claims (6)
1. A liquid compounding system, characterized by: the novel liquid suction device comprises a first pump (9), a second pump (13) and a contact pin (26), wherein the contact pin (26) comprises a fixed plate (268), a liquid inlet pipe (261) and a liquid outlet pipe (262) which are communicated with the fixed plate (268) are arranged on the fixed plate (268), the inlet end of the liquid inlet pipe (261) is communicated with a first liquid supply pipe (27), the first pump (9) is arranged on the first liquid supply pipe (27), the outlet end of the liquid outlet pipe (262) is communicated with a second liquid suction pipe (20), and the second pump (13) is arranged on the second liquid suction pipe (20);
the automatic feeding and conveying device is characterized by further comprising a feeding and conveying mechanism, wherein the feeding and conveying mechanism comprises a rotary table (21), a rotary shaft (24) and a rotary table driving motor, a limiting sink (211) is formed on the rotary table (21), the rotary shaft (24) is fixedly connected with the rotary table (21), a mutually perpendicular structure is formed between the rotary shaft (24) and the limiting sink (211), and the rotary table driving motor drives the rotary shaft (24) to do rotary motion;
the contact pin (26) is fixedly connected with the lifting mechanism (19) through the fixing plate (268), and the lifting mechanism (19) controls the contact pin (26) to move up and down in a straight line;
the device also comprises a dilution bottle (4) and a second liquid supply pipe (28), wherein the opposite ends of the second liquid supply pipe (28) are respectively communicated with the dilution bottle (4) and the first liquid supply pipe (27);
the dilution bottle (4) is of a hollow cavity structure, a first pipeline interface (41) and a third pipeline interface (44) are fixedly connected to two opposite ends of the dilution bottle (4) respectively, the first pipeline interface (41) and the third pipeline interface (44) are communicated with a hollow inner cavity of the dilution bottle (4), a flow guide structure (45) is arranged at the bottom of the hollow inner cavity of the dilution bottle (4), and the lowest point of the flow guide structure (45) is communicated with the third pipeline interface (44).
2. A liquid compounding system as defined in claim 1, wherein: the lifting mechanism (19) comprises a frame (195), a screw rod (191), a slide block (193) and a stepping motor (192), wherein the screw rod (191) is arranged on the frame (195), the screw rod (191) and the slide block (193) form threaded movable connection, and the slide block (193) is fixedly connected with the fixed plate (268); the stepping motor (192) drives the screw rod (191) to rotate relative to the frame (195), and the slider (193) drives the contact pin (26) to move up and down linearly relative to the screw rod (191).
3. A liquid compounding system as defined in claim 1, wherein: the device also comprises an analysis bottle (7), wherein the analysis bottle (7) is connected and communicated with the dilution bottle (4) through a first liquid suction pipe (5), and a fourth pump (17) is arranged on the first liquid suction pipe (5).
4. A liquid compounding system as defined in claim 3, wherein: the analysis bottle (7) is of a hollow cavity structure, the two opposite ends of the analysis bottle (7) are respectively and fixedly connected with a liquid inlet pipeline interface (71) and a liquid outlet pipeline interface (72), the liquid inlet pipeline interface (71) and the liquid outlet pipeline interface (72) are communicated with the hollow inner cavity of the analysis bottle (7), a drainage structure (74) is arranged at the bottom of the hollow inner cavity of the analysis bottle (7), and the lowest point of the drainage structure (74) is communicated with the liquid outlet pipeline interface (72).
5. A liquid compounding system as defined in claim 1, wherein: the liquid taking bottle (10) is connected and communicated with the dilution bottle (4) through a liquid taking pipe (8), and a third pump (15) is arranged on the liquid taking pipe (8).
6. A liquid mixing method, which is characterized in that: use of a liquid compounding system according to any one of claims 1-5, comprising the steps of:
s1, connecting and communicating a first liquid supply pipe (27) with a liquid supply bottle (1), connecting and communicating a second liquid suction pipe (20) with a dilution bottle (4), placing a stock solution bottle (25) containing stock solution below a contact pin (26), and injecting the stock solution into the liquid supply bottle (1);
s2, enabling the bottom of the contact pin (26) to be inserted into the inner cavity of the stock solution bottle (25), starting the second pump (13), extracting stock solution from the stock solution bottle (25) to the dilution bottle (4), starting the first pump (9), and extracting the liquid from the liquid supply bottle (1) to the dilution bottle (4).
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