CN105848687B - 放射性示踪剂组合物和方法 - Google Patents

放射性示踪剂组合物和方法 Download PDF

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Publication number
CN105848687B
CN105848687B CN201480069324.9A CN201480069324A CN105848687B CN 105848687 B CN105848687 B CN 105848687B CN 201480069324 A CN201480069324 A CN 201480069324A CN 105848687 B CN105848687 B CN 105848687B
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radiotracer
solution
formula
fluorobenzaldehyde
reversed
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Chinese (zh)
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CN105848687A (zh
Inventor
T.恩格尔
G.S.格特福尔德森
A.R.迈耶尔
I.A.卡恩
R.J.奈尔内
G.麦克罗比
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GE Healthcare Ltd
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GE Healthcare Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201480069324.9A 2013-12-18 2014-12-18 放射性示踪剂组合物和方法 Active CN105848687B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1322456.3 2013-12-18
GBGB1322456.3A GB201322456D0 (en) 2013-12-18 2013-12-18 Radiotracer compositions and methods
PCT/EP2014/078609 WO2015091882A1 (en) 2013-12-18 2014-12-18 Radiotracer compositions and methods

Publications (2)

Publication Number Publication Date
CN105848687A CN105848687A (zh) 2016-08-10
CN105848687B true CN105848687B (zh) 2020-06-09

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CN201480069324.9A Active CN105848687B (zh) 2013-12-18 2014-12-18 放射性示踪剂组合物和方法

Country Status (6)

Country Link
US (3) US10300156B2 (https=)
EP (1) EP3082879A1 (https=)
JP (2) JP6824738B2 (https=)
CN (1) CN105848687B (https=)
GB (1) GB201322456D0 (https=)
WO (1) WO2015091882A1 (https=)

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GB201915206D0 (en) 2019-10-21 2019-12-04 Ge Healthcare Ltd Use of cyclodextrins as a radiostabilizer
GB201919016D0 (en) * 2019-12-20 2020-02-05 Ge Healthcare Ltd Apparatus and method for solid phase extraction
EP4087592A1 (en) * 2020-01-10 2022-11-16 Real Isolates, LLC Methods for obtaining compounds from a plant or fungus material, respective compositions, and uses thereof

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GB201322456D0 (en) * 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
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US20090274623A1 (en) * 2008-01-30 2009-11-05 General Electric Company In vivo imaging agents for met receptor tyrosine kinase
CN103153350A (zh) * 2010-08-18 2013-06-12 通用电气健康护理有限公司 肽放射性示踪剂组合物
WO2012087725A1 (en) * 2010-12-21 2012-06-28 Ge Healthcare Limited Use of aniline iν the radiostabilization of oxime ligation
WO2013174909A1 (en) * 2012-05-24 2013-11-28 Ge Healthcare Limited Purification of [18f] - fluciclatide

Also Published As

Publication number Publication date
CN105848687A (zh) 2016-08-10
JP2017502946A (ja) 2017-01-26
GB201322456D0 (en) 2014-02-05
WO2015091882A1 (en) 2015-06-25
JP6824738B2 (ja) 2021-02-03
US10300156B2 (en) 2019-05-28
US11311636B2 (en) 2022-04-26
JP2019206533A (ja) 2019-12-05
US20220202965A1 (en) 2022-06-30
US20160303263A1 (en) 2016-10-20
EP3082879A1 (en) 2016-10-26
US20190275182A1 (en) 2019-09-12

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