CN105848587B - 光声显微镜 - Google Patents

光声显微镜 Download PDF

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Publication number
CN105848587B
CN105848587B CN201480070297.7A CN201480070297A CN105848587B CN 105848587 B CN105848587 B CN 105848587B CN 201480070297 A CN201480070297 A CN 201480070297A CN 105848587 B CN105848587 B CN 105848587B
Authority
CN
China
Prior art keywords
photoacoustic
depth
time
photoacoustic wave
specimen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201480070297.7A
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English (en)
Chinese (zh)
Other versions
CN105848587A (zh
Inventor
村山义彰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
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Olympus Corp
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Publication of CN105848587A publication Critical patent/CN105848587A/zh
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Publication of CN105848587B publication Critical patent/CN105848587B/zh
Expired - Fee Related legal-status Critical Current
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/04—Analysing solids
    • G01N29/06—Visualisation of the interior, e.g. acoustic microscopy
    • G01N29/0654—Imaging
    • G01N29/0681—Imaging by acoustic microscopy, e.g. scanning acoustic microscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G01N29/032—Analysing fluids by measuring attenuation of acoustic waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22—Details, e.g. general constructional or apparatus details
    • G01N29/24—Probes
    • G01N29/2418—Probes using optoacoustic interaction with the material, e.g. laser radiation, photoacoustics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/44—Processing the detected response signal, e.g. electronic circuits specially adapted therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/44—Processing the detected response signal, e.g. electronic circuits specially adapted therefor
    • G01N29/4409—Processing the detected response signal, e.g. electronic circuits specially adapted therefor by comparison
    • G01N29/4427—Processing the detected response signal, e.g. electronic circuits specially adapted therefor by comparison with stored values, e.g. threshold values
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/024—Mixtures
    • G01N2291/02483—Other human or animal parts, e.g. bones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/028—Material parameters
    • G01N2291/0289—Internal structure, e.g. defects, grain size, texture
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/26—Scanned objects
    • G01N2291/263—Surfaces

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Optics & Photonics (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
CN201480070297.7A 2013-12-25 2014-12-11 光声显微镜 Expired - Fee Related CN105848587B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013267398A JP6210873B2 (ja) 2013-12-25 2013-12-25 光音響顕微鏡
JP2013-267398 2013-12-25
PCT/JP2014/006182 WO2015098018A1 (ja) 2013-12-25 2014-12-11 光音響顕微鏡

Publications (2)

Publication Number Publication Date
CN105848587A CN105848587A (zh) 2016-08-10
CN105848587B true CN105848587B (zh) 2018-10-02

Family

ID=53477924

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480070297.7A Expired - Fee Related CN105848587B (zh) 2013-12-25 2014-12-11 光声显微镜

Country Status (5)

Country Link
US (1) US10309933B2 (enExample)
JP (1) JP6210873B2 (enExample)
CN (1) CN105848587B (enExample)
DE (1) DE112014005466T5 (enExample)
WO (1) WO2015098018A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6358735B2 (ja) * 2014-02-26 2018-07-18 オリンパス株式会社 光音響顕微鏡装置
KR101808173B1 (ko) * 2016-07-21 2017-12-12 포항공과대학교 산학협력단 광음향 현미경의 성능을 향상시키는 시간지연곱합 기반 합성개구집속 방법, 및 이를 이용하는 프로세싱 장치 및 광음향 현미경 시스템
KR101936120B1 (ko) * 2016-11-30 2019-01-08 부경대학교 산학협력단 광음향 단층촬영을 위한 프로브 및 실시간 광음향 단층촬영 장치
WO2018135005A1 (ja) * 2017-01-23 2018-07-26 オリンパス株式会社 信号処理装置、光音響波撮影装置および信号処理方法
CN108742528B (zh) * 2018-05-29 2021-12-10 华南师范大学 一种无水耦合的快速线性共焦扫描光声探头及其成像方法
CN116183507A (zh) * 2022-05-30 2023-05-30 香港理工大学深圳研究院 一种基于基底光声的组织硬度研究方法及应用

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1401070A (zh) * 2000-04-26 2003-03-05 爱德万测试株式会社 电子束长度测量装置和长度测量方法
CN101002670A (zh) * 2006-01-20 2007-07-25 奥林巴斯医疗株式会社 被检体信息分析装置、内窥镜装置、被检体信息分析方法
CN101918811A (zh) * 2007-10-25 2010-12-15 圣路易斯华盛顿大学 具有光学横向分辨率的共焦光声显微镜
CN102439418A (zh) * 2009-06-12 2012-05-02 奥林巴斯株式会社 被检体信息分析装置以及被检体信息分析方法
JP2012163526A (ja) * 2011-02-09 2012-08-30 Canon Inc 測定装置
WO2012174413A1 (en) * 2011-06-15 2012-12-20 University Of Southern California Optical coherence photoacoustic microscopy
CN103076286A (zh) * 2011-10-26 2013-05-01 联发科技股份有限公司 用于观察物体的光声显微镜系统及其方法
JP2013113804A (ja) * 2011-11-30 2013-06-10 Olympus Corp 光音響顕微鏡

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2659429B2 (ja) * 1989-03-17 1997-09-30 株式会社日立製作所 光音響信号検出方法及びその装置並びに半導体素子内部欠陥検出方法
US5136172A (en) * 1989-08-16 1992-08-04 Hitachi, Ltd. Method and apparatus for detecting photoacoustic signal
WO2009073979A1 (en) * 2007-12-12 2009-06-18 Carson Jeffrey J L Three-dimensional photoacoustic imager and methods for calibrating an imager
JPWO2011052061A1 (ja) * 2009-10-29 2013-03-14 キヤノン株式会社 光音響装置
JP2012075511A (ja) * 2010-09-30 2012-04-19 Fujifilm Corp 光音響画像診断装置、画像生成方法、及びプログラム
WO2014103106A1 (ja) * 2012-12-25 2014-07-03 オリンパス株式会社 光音響顕微鏡

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1401070A (zh) * 2000-04-26 2003-03-05 爱德万测试株式会社 电子束长度测量装置和长度测量方法
CN101002670A (zh) * 2006-01-20 2007-07-25 奥林巴斯医疗株式会社 被检体信息分析装置、内窥镜装置、被检体信息分析方法
CN101918811A (zh) * 2007-10-25 2010-12-15 圣路易斯华盛顿大学 具有光学横向分辨率的共焦光声显微镜
CN102439418A (zh) * 2009-06-12 2012-05-02 奥林巴斯株式会社 被检体信息分析装置以及被检体信息分析方法
JP2012163526A (ja) * 2011-02-09 2012-08-30 Canon Inc 測定装置
WO2012174413A1 (en) * 2011-06-15 2012-12-20 University Of Southern California Optical coherence photoacoustic microscopy
CN103076286A (zh) * 2011-10-26 2013-05-01 联发科技股份有限公司 用于观察物体的光声显微镜系统及其方法
JP2013113804A (ja) * 2011-11-30 2013-06-10 Olympus Corp 光音響顕微鏡

Also Published As

Publication number Publication date
JP2015123098A (ja) 2015-07-06
WO2015098018A1 (ja) 2015-07-02
CN105848587A (zh) 2016-08-10
US20160305912A1 (en) 2016-10-20
DE112014005466T5 (de) 2016-08-18
JP6210873B2 (ja) 2017-10-11
US10309933B2 (en) 2019-06-04

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Granted publication date: 20181002

Termination date: 20191211