CN105831738A - Polypeptide glucosamine chondroitin nutritional health food - Google Patents
Polypeptide glucosamine chondroitin nutritional health food Download PDFInfo
- Publication number
- CN105831738A CN105831738A CN201610193657.3A CN201610193657A CN105831738A CN 105831738 A CN105831738 A CN 105831738A CN 201610193657 A CN201610193657 A CN 201610193657A CN 105831738 A CN105831738 A CN 105831738A
- Authority
- CN
- China
- Prior art keywords
- parts
- glucosamine
- polypeptide
- powder
- human body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 71
- 229920001184 polypeptide Polymers 0.000 title claims abstract description 41
- 102000004196 processed proteins & peptides Human genes 0.000 title claims abstract description 41
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 title claims abstract description 21
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 10
- 235000013402 health food Nutrition 0.000 title claims abstract description 8
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 title abstract description 12
- 229960002442 glucosamine Drugs 0.000 title abstract description 11
- 229920002567 Chondroitin Polymers 0.000 title abstract description 3
- DLGJWSVWTWEWBJ-HGGSSLSASA-N chondroitin Chemical compound CC(O)=N[C@@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@H](O)C=C(C(O)=O)O1 DLGJWSVWTWEWBJ-HGGSSLSASA-N 0.000 title abstract description 3
- 239000000843 powder Substances 0.000 claims abstract description 46
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 40
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims abstract description 33
- 229920001287 Chondroitin sulfate Polymers 0.000 claims abstract description 33
- 229940059329 chondroitin sulfate Drugs 0.000 claims abstract description 33
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 20
- 239000002994 raw material Substances 0.000 claims abstract description 11
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 7
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 7
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 7
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 6
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 34
- MTDHILKWIRSIHB-UHFFFAOYSA-N (5-azaniumyl-3,4,6-trihydroxyoxan-2-yl)methyl sulfate Chemical compound NC1C(O)OC(COS(O)(=O)=O)C(O)C1O MTDHILKWIRSIHB-UHFFFAOYSA-N 0.000 claims description 26
- 229960002849 glucosamine sulfate Drugs 0.000 claims description 26
- 235000019359 magnesium stearate Nutrition 0.000 claims description 17
- MSWZFWKMSRAUBD-QZABAPFNSA-N beta-D-glucosamine Chemical compound N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-QZABAPFNSA-N 0.000 claims description 8
- 235000008935 nutritious Nutrition 0.000 claims description 8
- 239000002775 capsule Substances 0.000 claims description 7
- 235000001497 healthy food Nutrition 0.000 claims description 7
- 230000035764 nutrition Effects 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 235000010469 Glycine max Nutrition 0.000 abstract description 25
- 230000000694 effects Effects 0.000 abstract description 21
- 239000008280 blood Substances 0.000 abstract description 10
- 210000004369 blood Anatomy 0.000 abstract description 10
- 201000008482 osteoarthritis Diseases 0.000 abstract description 8
- 230000017531 blood circulation Effects 0.000 abstract description 7
- 244000068988 Glycine max Species 0.000 abstract description 6
- 230000000968 intestinal effect Effects 0.000 abstract description 5
- 230000032683 aging Effects 0.000 abstract description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 4
- 230000002265 prevention Effects 0.000 abstract description 4
- 230000004089 microcirculation Effects 0.000 abstract description 3
- 235000000346 sugar Nutrition 0.000 abstract description 3
- 230000002526 effect on cardiovascular system Effects 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract description 2
- 230000002792 vascular Effects 0.000 abstract description 2
- FGNPLIQZJCYWLE-BTVCFUMJSA-N (2r,3r,4s,5r)-2-amino-3,4,5,6-tetrahydroxyhexanal;sulfuric acid Chemical compound OS(O)(=O)=O.O=C[C@H](N)[C@@H](O)[C@H](O)[C@H](O)CO FGNPLIQZJCYWLE-BTVCFUMJSA-N 0.000 abstract 1
- 241000186000 Bifidobacterium Species 0.000 abstract 1
- 241000186660 Lactobacillus Species 0.000 abstract 1
- 235000021355 Stearic acid Nutrition 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 229940039696 lactobacillus Drugs 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 abstract 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 239000008117 stearic acid Substances 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 description 22
- 210000000845 cartilage Anatomy 0.000 description 13
- 239000000047 product Substances 0.000 description 12
- 230000006870 function Effects 0.000 description 11
- 239000000463 material Substances 0.000 description 10
- 238000007796 conventional method Methods 0.000 description 8
- 235000013305 food Nutrition 0.000 description 8
- 238000002360 preparation method Methods 0.000 description 8
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 7
- 208000002193 Pain Diseases 0.000 description 7
- 235000001014 amino acid Nutrition 0.000 description 7
- 150000001413 amino acids Chemical class 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 7
- 210000001612 chondrocyte Anatomy 0.000 description 7
- 238000003756 stirring Methods 0.000 description 7
- 210000001519 tissue Anatomy 0.000 description 7
- 230000008901 benefit Effects 0.000 description 6
- 229920002678 cellulose Polymers 0.000 description 6
- 239000001913 cellulose Substances 0.000 description 6
- 235000010980 cellulose Nutrition 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 239000008103 glucose Substances 0.000 description 6
- 206010061218 Inflammation Diseases 0.000 description 5
- 208000012659 Joint disease Diseases 0.000 description 5
- 230000033228 biological regulation Effects 0.000 description 5
- 230000004054 inflammatory process Effects 0.000 description 5
- 235000018102 proteins Nutrition 0.000 description 5
- 102000004169 proteins and genes Human genes 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- 238000003786 synthesis reaction Methods 0.000 description 5
- 239000011573 trace mineral Substances 0.000 description 5
- 235000013619 trace mineral Nutrition 0.000 description 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 4
- 210000001188 articular cartilage Anatomy 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 4
- 239000011575 calcium Substances 0.000 description 4
- 229910052791 calcium Inorganic materials 0.000 description 4
- 230000036039 immunity Effects 0.000 description 4
- 229910052500 inorganic mineral Inorganic materials 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- 239000011707 mineral Substances 0.000 description 4
- 235000010755 mineral Nutrition 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 235000015097 nutrients Nutrition 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 4
- 230000008439 repair process Effects 0.000 description 4
- 239000001117 sulphuric acid Substances 0.000 description 4
- 235000011149 sulphuric acid Nutrition 0.000 description 4
- 230000001629 suppression Effects 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- 208000006820 Arthralgia Diseases 0.000 description 3
- 229920002101 Chitin Polymers 0.000 description 3
- 102000008186 Collagen Human genes 0.000 description 3
- 108010035532 Collagen Proteins 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 108010001441 Phosphopeptides Proteins 0.000 description 3
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 3
- 206010042674 Swelling Diseases 0.000 description 3
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 3
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 3
- 235000011130 ammonium sulphate Nutrition 0.000 description 3
- 229940071162 caseinate Drugs 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 230000002354 daily effect Effects 0.000 description 3
- 210000002249 digestive system Anatomy 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- -1 ester sodium salt Chemical class 0.000 description 3
- 230000001771 impaired effect Effects 0.000 description 3
- 239000004310 lactic acid Substances 0.000 description 3
- 235000012054 meals Nutrition 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 210000000582 semen Anatomy 0.000 description 3
- 241000894007 species Species 0.000 description 3
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 210000001258 synovial membrane Anatomy 0.000 description 3
- HIXDQWDOVZUNNA-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxychromen-4-one Chemical compound C=1C(OC)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(OC)C(OC)=C1 HIXDQWDOVZUNNA-UHFFFAOYSA-N 0.000 description 2
- 239000004382 Amylase Substances 0.000 description 2
- 108010065511 Amylases Proteins 0.000 description 2
- 102000013142 Amylases Human genes 0.000 description 2
- 201000001320 Atherosclerosis Diseases 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 208000002513 Flank pain Diseases 0.000 description 2
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 229920002683 Glycosaminoglycan Polymers 0.000 description 2
- 206010020880 Hypertrophy Diseases 0.000 description 2
- AEMOLEFTQBMNLQ-HNFCZKTMSA-N L-idopyranuronic acid Chemical compound OC1O[C@@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-HNFCZKTMSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 208000001132 Osteoporosis Diseases 0.000 description 2
- 108010019160 Pancreatin Proteins 0.000 description 2
- 102000057297 Pepsin A Human genes 0.000 description 2
- 108090000284 Pepsin A Proteins 0.000 description 2
- RXUWDKBZZLIASQ-UHFFFAOYSA-N Puerarin Natural products OCC1OC(Oc2c(O)cc(O)c3C(=O)C(=COc23)c4ccc(O)cc4)C(O)C(O)C1O RXUWDKBZZLIASQ-UHFFFAOYSA-N 0.000 description 2
- 108010073771 Soybean Proteins Proteins 0.000 description 2
- 206010041591 Spinal osteoarthritis Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000001166 ammonium sulphate Substances 0.000 description 2
- 235000019418 amylase Nutrition 0.000 description 2
- 230000003064 anti-oxidating effect Effects 0.000 description 2
- 230000002785 anti-thrombosis Effects 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 230000008827 biological function Effects 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 230000003139 buffering effect Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000007850 degeneration Effects 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 102000038379 digestive enzymes Human genes 0.000 description 2
- 108091007734 digestive enzymes Proteins 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000007071 enzymatic hydrolysis Effects 0.000 description 2
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 2
- 229940088598 enzyme Drugs 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 229930003944 flavone Natural products 0.000 description 2
- 235000011949 flavones Nutrition 0.000 description 2
- 230000007661 gastrointestinal function Effects 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 150000002338 glycosides Chemical class 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 210000000629 knee joint Anatomy 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 230000001050 lubricating effect Effects 0.000 description 2
- 210000004165 myocardium Anatomy 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 229940055695 pancreatin Drugs 0.000 description 2
- 229940111202 pepsin Drugs 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- HKEAFJYKMMKDOR-VPRICQMDSA-N puerarin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=CC(C2=O)=C1OC=C2C1=CC=C(O)C=C1 HKEAFJYKMMKDOR-VPRICQMDSA-N 0.000 description 2
- 210000000323 shoulder joint Anatomy 0.000 description 2
- 235000019710 soybean protein Nutrition 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 230000035882 stress Effects 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- CVCQAQVBOPNTFI-AAONGDSNSA-N (3r,4r,5s,6r)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol;sulfuric acid Chemical compound OS(O)(=O)=O.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O CVCQAQVBOPNTFI-AAONGDSNSA-N 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241000186016 Bifidobacterium bifidum Species 0.000 description 1
- 206010005963 Bone formation increased Diseases 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 206010006811 Bursitis Diseases 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- 206010007710 Cartilage injury Diseases 0.000 description 1
- 239000003390 Chinese drug Substances 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
- 241000251730 Chondrichthyes Species 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 241000238557 Decapoda Species 0.000 description 1
- 206010013911 Dysgeusia Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 208000007875 Femur Head Necrosis Diseases 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- FZHXIRIBWMQPQF-UHFFFAOYSA-N Glc-NH2 Natural products O=CC(N)C(O)C(O)C(O)CO FZHXIRIBWMQPQF-UHFFFAOYSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 241000521257 Hydrops Species 0.000 description 1
- 206010020651 Hyperkinesia Diseases 0.000 description 1
- 208000000269 Hyperkinesis Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 206010023232 Joint swelling Diseases 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
- OVRNDRQMDRJTHS-CBQIKETKSA-N N-Acetyl-D-Galactosamine Chemical compound CC(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@H](O)[C@@H]1O OVRNDRQMDRJTHS-CBQIKETKSA-N 0.000 description 1
- 125000003047 N-acetyl group Chemical group 0.000 description 1
- MBLBDJOUHNCFQT-UHFFFAOYSA-N N-acetyl-D-galactosamine Natural products CC(=O)NC(C=O)C(O)C(O)C(O)CO MBLBDJOUHNCFQT-UHFFFAOYSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010034464 Periarthritis Diseases 0.000 description 1
- 244000046146 Pueraria lobata Species 0.000 description 1
- 235000010575 Pueraria lobata Nutrition 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 241000282898 Sus scrofa Species 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- 208000001435 Thromboembolism Diseases 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 238000005903 acid hydrolysis reaction Methods 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- IAJILQKETJEXLJ-QTBDOELSSA-N aldehydo-D-glucuronic acid Chemical compound O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-QTBDOELSSA-N 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 210000000544 articulatio talocruralis Anatomy 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000037429 base substitution Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N benzo-alpha-pyrone Natural products C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- QXMNTPFFZFYQAI-IMDKZJJXSA-N beta-sitosterol 3-O-beta-D-glucopyranoside Natural products CC[C@H](CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)O[C@@H]5C[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(C)C QXMNTPFFZFYQAI-IMDKZJJXSA-N 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 210000003321 cartilage cell Anatomy 0.000 description 1
- 230000008421 cartilage matrix synthesis Effects 0.000 description 1
- 230000001925 catabolic effect Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 208000036319 cervical spondylosis Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000011443 conventional therapy Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 235000001671 coumarin Nutrition 0.000 description 1
- 150000004775 coumarins Chemical class 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- NPJICTMALKLTFW-OFUAXYCQSA-N daucosterol Chemical compound O([C@@H]1CC2=CC[C@H]3[C@@H]4CC[C@@H]([C@]4(CC[C@@H]3[C@@]2(C)CC1)C)[C@H](C)CC[C@@H](CC)C(C)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O NPJICTMALKLTFW-OFUAXYCQSA-N 0.000 description 1
- QDFKFNAHVGPRBL-UHFFFAOYSA-N daucosterol Natural products CCC(CCC(C)C1CCC2C1CCC3C2(C)CC=C4CC(CCC34C)OC5OC(CO)C(O)C(O)C5O)C(C)C QDFKFNAHVGPRBL-UHFFFAOYSA-N 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000003412 degenerative effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 235000008242 dietary patterns Nutrition 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000003797 essential amino acid Substances 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 201000010934 exostosis Diseases 0.000 description 1
- 210000000887 face Anatomy 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 229940097043 glucuronic acid Drugs 0.000 description 1
- 150000002333 glycines Chemical class 0.000 description 1
- 150000002337 glycosamines Chemical class 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 210000004247 hand Anatomy 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 150000002402 hexoses Chemical class 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 210000004394 hip joint Anatomy 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 201000010930 hyperostosis Diseases 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000031891 intestinal absorption Effects 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- 210000005067 joint tissue Anatomy 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000037356 lipid metabolism Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000002324 minimally invasive surgery Methods 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000008557 oxygen metabolism Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 239000003531 protein hydrolysate Substances 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 108010048734 sclerotin Proteins 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 210000002832 shoulder Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000003093 somatogenic effect Effects 0.000 description 1
- 208000005801 spondylosis Diseases 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000004206 stomach function Effects 0.000 description 1
- 210000001138 tear Anatomy 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 210000003857 wrist joint Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention discloses a polypeptide glucosamine chondroitin nutritional health food. The nutritional health food is prepared from the following raw materials in parts by weight: 20-35 parts of D-Glucosamine sulfate, 20-35 parts of chondroitin sulfate, 10-20 parts of soybean peptide powder, 5-10 parts of radix puerariae powder, 5-10 parts of calcium carbonate, 5-10 parts of microcrystalline cellulose and 1-3 parts of stearic acid. The nutritional health food is prone to being absorbed by the human body, suitable for the treatment and prevention of osteoarthritis in all parts of the human body; at the same time, the nutritional health food has effects in resisting thrombosis, improving cardiovascular and cerebrovascular blood flow and vascular microcirculation disorder, lowering blood lipid, regulating blood sugar, promoting the proliferation of intestinal Bifidobacterium and Lactobacillus, removing free radicals in the human body, delaying aging, etc.
Description
Technical field
The invention belongs to food technology field, be specifically related to a kind of polypeptide food.
Background technology
In economic development to certain phase, level of consumption rises, and after eating patterns adjust, people are taken in food
Essential amino acids, such as arginine, glycine does not lack, but some peptide over time with the age increase may lack and necessary
Supplement, to improve " subhealth state " state of modern.Therefore, scientist advises, for somatogenic need, is meeting the base of human body
After this nutrition intake, suitably supplement polypeptide nutrition, healthy and rehabilitation are of great benefit to.
Polypeptide is the compound that a-amino acid is formed so that peptide chain links together, and it is also the centre of proteolysis
Product, its molecular weight is less than 10000 dalton, through semipermeable membrane and can not precipitated by trichloroacetic acid and ammonium sulfate.
Scientific research finds, protein, after digestive tract enzymatic hydrolysis, is mainly absorbed with the form of little peptide, and ratio is swum completely
Isolated amino acid is more easy to, and is faster absorbed by organisms utilization.The mechanism of absorption of polypeptide has ten big features:
1, it is not required to digestion, directly absorbs.Generally, polypeptide is human body self synthesis, and protein enzymatic hydrolysis becomes aminoacid, then
Synthetic peptide, absorbs eventually through small intestinal;And the polypeptide surface of synthetic has layer protecting film, will not be promoted by human body
Enzyme, pepsin, pancreatin, amylase, digestive enzyme and acid-base material secondary hydrolyze, and it is directly entered small intestinal with complete form,
Absorbed by small intestinal, enter human recycle system, play biological function.
2, absorb quickly.Oral agents is such as injection, the polypeptide synthesized outside prosthesis, oral entrance human body, it is possible to rapidly
Through oral cavity, the stomach of people, it is directly entered small intestinal, by intestinal absorption, eventually enters into blood circulation of human body system, organ and groups of cells
Knit, play rapidly its physiological action and biological function.
When 3, absorbing, polypeptide body will not be destroyed.Polypeptide body self has layer protecting film, when people takes, and will not be by people
The infringement of the acid-base material promoted in enzyme, pancreatin, amylase, digestive enzyme, pepsin and digestive system in body or secondary hydrolysis,
Polypeptide is to be absorbed and utilized by the body with complete form.
4, polypeptide has 100% feature being absorbed by the body.After absorption, do not have Excreta, and be all to be inhaled by human body
Receive and utilize.
5, polypeptide has the advantages that actively be absorbed by the body.For because of digestive system defect, obstacle, damage, and can not inhale
Receiving nutrition person, polypeptide has actively allows absorption of human body or force allow the feature of absorption of human body.This is poor for those digestion powers, battalion
Support and lack, physical weakness, valetudinarian, have great significance.
6, polypeptide has the advantages that preferentially be absorbed by the body.The nutrient substance that people are eaten usually, on absorbing, with polypeptide
Competition in, polypeptide has the feature of preferential absorption.This is undivided with the feature of its active absorption.
7, the human body absorption to polypeptide, has and is not required to expend body energy, is not required to increase digestive tract, particularly gastrointestinal function
Burden.Polypeptide self has extremely strong activity and energy, its active absorption, forces absorption, it is simply that the activity of self and energy
In action.Therefore, it is when being absorbed by the body, and is not that human body to expend self energy and goes to absorb it, but polypeptide with from
The energy of body is by absorption of human body.From this, the infant that its this distinguishing feature is to digestive system undeveloped mature, offset
Change system starts the old people of degeneration and is badly in need of nitrogen source because of hyperkinesia, and can not increase the motion of gastrointestinal function burden
Member, physical labourer important in inhibiting.
8, the carrier function that polypeptide shows in human body, the nutrient substance that can mediocrity be eaten, particularly calcium etc. are right
The trace element that human body is useful, adsorbs, pastes, is loaded on body.
9, polypeptide can play the effect of means of transport in human body.The various nutrient substance absorption that can people be usually eaten is at this
After on body, then delivery is transported to each cell of human body, organ, tissue, is absorbed and utilized by the body together with body, plays each
From different functions.Here it is at present the most in the world people using former as medicine and food formula of polypeptide raw material midbody
Cause, its purpose is to strengthen drug effect, strengthens absorbance.
10, after polypeptide is absorbed by the body, courier's effect can be played in human body.It transmits information as neurotransmitter, commander
Nerve, plays self-acting, safeguards team spirit and the group effect of human nerve, make human body become more flexible, sensitive, clever
Intelligent.In a word, the mechanism of absorption of polypeptide differs widely with the mechanism of absorption of other various materials.
Glucosamine, it is the compound that a hydroxyl of glucose is replaced by an amino.Molecular formula C6H13O5N,
It is commonly called as amino sugar, is called for short D-glucosamine.Having another name called glucamine, be widely present in nature, 2-amino-2-deoxy-D-Glucose is usual
With N-acetyl derivative (such as chitin) or it is present in micro-with N-sulfuric ester and N-acetyl-3-O-lactic acid ether (3-O-.alpha.-carboxyethyl-D-glucosamine .) form
Biological, the polysaccharide of animal origin and combining in polysaccharide.Glucosamine is the material of the interior synthesis of human body, is to form chondrocyte
Important nutrient, is the natural tissues composition of healthy articular cartilage.With advancing age, the glucosamine in human body is scarce
Weary increasingly severe, articular cartilage is constantly degenerated and weares and teares.The U.S., European and Japanese a large amount of medical researches show: amino Portugal
Grape sugar can help repair and safeguard cartilage, and can stimulate the growth of chondrocyte.
Chondroitin sulfate is to extract, from pig, cattle, chicken, the cartilaginous tissue such as cartilage of shark, the acidic mucopolysaccharide prepared.Sulphuric acid
Chrondroitin is mainly N-acetylgalactosamine (2-acetamide-2-deoxidation ratio mutter galactose) and 1 > Portugal chondroitin sulfate natrium capsule grape
The sulfuric ester sodium salt of the copolymer of alduronic acid, in copolymer, hexose is alternately connected by 1,3 and Isosorbide-5-Nitrae glycosidic bond, its molecular weight one
As be 2~50,000 dalton, white powder, have compared with strong absorptive, soluble in water and become viscous solution, insoluble in ethanol, second
Ether, acetone and other organic solvent.
Through retrieval, contain the patent of chondroitin sulfate and glucosamine sulfate has ten multinomial, such as " degenerated joint simultaneously
Scorching and the medicament composing prescription of osteoporosis and method for preparing tablet thereof thereof " (number of patent application: 201510657601.4) and " a kind of increasing
Health food of bone strengthening density and immunity and preparation method thereof " (number of patent application: 201410116440.3), above-mentioned two is special
Profit all contains phosphopeptide caseinate, but phosphopeptide caseinate is expensive, the most all at 2000 yuans/kilogram, and consumption
Person is beyond affordability;It addition, phosphopeptide caseinate lacks special medicinal function such as thromboembolism preventing, suppression platelet aggregation and promotes mineral
And the absorption etc. of trace element.The product of current glucosamine chondroitin sulfate is a lot, but also has in absorption of human body effect
Wait to inquire into.
Joint disease is a kind of disease being common in middle-aged and elderly people, and it includes degenerative osteoarthritis, bursitis, synovial membrane
Inflammation, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, hyperosteogeny, rheumatic arthritis, rheumatoid arthritis, femur head necrosis etc., suffer from
Sick basic reason is not that skeleton there occurs pathological changes, and modern medicine study finds, old complaint is that " the joint protection systems such as cartilage
System " forfeiture to joint protective capability.
It is in particular in: the generation of diverse bone types joint disease often starts from that the lesions of synovium contributed, cartilage be impaired or degeneration;Take
The cartilage injury that some antiinflammatory class, hormone medicine are caused also is one of main reason of many joint disease.Owing to closing
Joint synovial membrane, the damage of cartilage and the disappearance of knuckle synovia, cause joint skeleton to lack the protection of necessity, to such an extent as to human body one lived
Dynamic, directly there is violent rigid friction in " cartilage protection " that the skeleton of joint is for want of necessary, and cause patient articular's pain,
The multiple symptoms such as swelling, deformation, bony spur hypertrophy.Even more important, if human synovial organ immune disorder, joint is inevitable because lacking
" immunoprotection " of weary necessity and cause the intrusion of extraneous inflammatory factor, ultimately result in the generation of diverse bone types joint disease.It faces
Show as on Chuan swollen joint, bitterly, hydrops, stiff, hypertrophy, bony spur, movable difficult, obstinate, the most repeatedly.
Summary of the invention
It is an object of the invention to provide a peptide species D-glucosamine chrondroitin nutritious and healthy food, its with glucosamine sulfate,
Chondroitin sulfate, soy peptide powder, powder of Radix Puerariae are primary raw material, utilize the carrier function of soy peptide powder, by glucosamine sulfate,
Chondroitin sulfate, powder of Radix Puerariae directly absorb in being conveyed into human body so that effect of each material composition is not fully exerted.This
Bright product it except have prevention and treatment general joint disease in addition to, also have antithrombus formation, suppression platelet aggregation, fall blood
Fat and cholesterol, promotion lipid metabolism, blood pressure lowering, antioxidation, anticancer, promotion mineral and the absorption of trace element, resisting fatigue
Act on regulation immunity etc..
Technical scheme is as follows:
One peptide species D-glucosamine chrondroitin nutritious and healthy food, its raw material and parts by weight are:
Glucosamine sulfate 20~35 parts
Chondroitin sulfate 20~35 parts
Soy peptide powder 10~20 parts
Powder of Radix Puerariae 5~10 parts
Calcium carbonate 5~10 parts
Microcrystalline Cellulose 2~5 parts
Magnesium stearate 1~3 parts.
Preferably weight proportion is:
Glucosamine sulfate 25~30 parts
Chondroitin sulfate 25~30 parts
Soy peptide powder 15~20 parts
Powder of Radix Puerariae 5~10 parts
Calcium carbonate 5~10 parts
Microcrystalline Cellulose 2~5 parts
Magnesium stearate 1~3 parts.
Above raw material is the most commercially available to be obtained, it is not necessary to prepare especially.
The polypeptide D-glucosamine chrondroitin nutritious and healthy food of the present invention can be prepared as tablet or capsule.
Product of the present invention can use customary preparation methods of the prior art.As first weighed former in proportion by above-mentioned formula
After material, be sufficiently mixed after fully pulverizing, stir powdering, sterilizes, sterilizes, dries, and then pours into capsule by conventional method
Make capsule, or use conventional method to do piece agent.
Primary raw material function introduction:
Glucosamine sulfate
Glucosamine sulfate be chitin (from shrimp and crab shells extract) or chitosan (extracting from chitin) be raw material, then
Glucosamine sulphate is made through sulphuric acid hydrolysis.
Glucosamine sulfate is a kind of aminopolysaccharide, and aminopolysaccharide is the ultimate constituent of articular cartilage, it is possible to promote
Enter chondrocyte synthesis, increase the stability of cell membrane, protect chondrocyte, delay conditions of patients to be in progress.Sulphuric acid amino simultaneously
Glucose is the highest with the affinity in joint, and the protein sugar glue compound that glucosamine sulfate is formed can be attached to substrate
Collagen is online, and synthesizes an elastomer with it, it is possible to play bearing pressure, buffering stress, the effect of conduction stress.Ammonium sulphate
Base glucose can also reflect proteoglycan degraded situation, repairs articular cartilage comprehensively, improves conditions of patients.
Glucosamine sulfate has effect of glucosamine simultaneously:
1, releive the pain because arthritis causes, stiff and swelling.
2, osteoporosis makes cartilage consume, and ultimately results in fragmentation and peels off, and joint has been lacked the buffering of cartilage, has been easily generated stiff
And inflammation.And glucosamine contributes to repairing damaged cartilage, stimulate the generation of new cartilage, improve inflammation symptom, joint of releiving
Pain, stiff and swelling.
3, strengthening cartilage structure, prevention function of joint lost efficacy
Along with body ages, joint tissue meeting heavy wear, glucosamine can be protected and strengthen cartilage structure, prevent because closing
Save function of joint that is aging and that produce to lose efficacy.
4, lubricating joint and maintenance function of joint
Glucosamine can manufacture proteoglycan lubricating joint, prevents osteoarthrosis friction pain, makes joint motion freely.
Chondroitin sulfate
Chondroitin sulfate (Chondroitin sulfate.CS) is the diverse location sulphuric acid of chrondroitin (Chondroitin.CH)
Base substitution product, is by alduronic acid (glucuronic acid GIcA/ iduronic acid IdoA), N mono-acetylamino galactosamine (G
A1NAc) and different content sulfate composition, it is a kind of acidic mucopolysaccharide, is generally widely present in the form of proteoglycan
In animal body.CS has blood fat reducing, atherosclerosis, enhancing immunity, antiviral hepatitis and antitumor isoreactivity.
Research proves, chondroitin sulfate can stimulate chondrocyte synthesis collagen protein and proteoglycan, promotes cartilage matrix
Synthesis, repair cartilaginous tissue, suppression cartilage degraded;Chondroitin sulfate also by promoting the growth of fiber in substrate, thus
Corneal collagen fiber play certain protective effect, strengthen permeability, promote the absorption of penetrating fluid, thus accelerate new old generation
Thank, blood circulation and the elimination of inflammation, clinically treatment osteoarthritis is had preferable effect;Meanwhile, chondroitin sulfate is also
There is anticoagulation, improve body's hypoxia tolerance, calmness, antitumor, antioxidation, regulation adhesion, protection neuron, tune
The several functions such as joint blood fat, antiviral and atherosclerosis.
Soy peptide powder
Soy peptide powder is also known as soybean polypeptide, and it is by obtained by hydrolysis low point be made up of 3 ~ 6 aminoacid of soybean protein
Sub-polypeptide, its molecular weight is below 1000 dalton.The protein content of soybean polypeptide is about 85%, and its aminoacid composition is several
Completely as soybean protein, it is necessary to amino acid whose balance is good, and content also enriches, the advantage with traditional polypeptide.It
It is more easy to be absorbed by the body than protein, there is antithrombotic, suppression platelet aggregation, blood pressure lowering, reduction blood fat, regulation blood glucose, rush
Enter enteral bacillus bifidus and the propagation of lactic acid bacteria, remove interior free yl, slow down aging, promotion mineral and the suction of trace element
The effects such as receipts, resisting fatigue and regulation immunity.At present, the market price of soybean polypeptide is 200 yuans/kilogram.
Radix Puerariae
Powder of Radix Puerariae be the dry root (practise claim Herba Gelsemii Elegantis) of legume pueraria lobata through being cut into sheet or fritter, crushed after being dried is made, taste
Sweet cool good to eat.Its main component is starch, contains the flavone compound of about 12% in addition, including Semen sojae atricolor (Semen Glycines) glycoside, Semen sojae atricolor
Glycoside unit, puerarins etc. more than 10 are planted;And containing daucosterol, aminoacid, Coumarins etc.;Also have protein, aminoacid, sugar and people
The mineral such as the required ferrum of body, calcium, copper, selenium, are all-ages famous and precious tonic, have the good reputation of " Radix Ginseng in thousand ".Radix Puerariae is
Chinese herbal medicines.
Radix Puerariae total flavones and puerarin in Radix Puerariae can improve myocardium oxygen metabolism, and myocardial metabolism is produced beneficial effect,
Blood vessel can be expanded simultaneously, improve microcirculation, reduce vascular resistance, make blood flow increase, therefore can be used for preventing and treating myocardial ischemia, cardiac muscle
Infarction, arrhythmia, hypertension, the disease such as arteriosclerosis.
Calcium carbonate
Calcium carbonate can be that human body supplements calcium ion, and calcium is the main component of sclerotin.
Microcrystalline Cellulose and magnesium stearate are mainly as excipient.
Glucosamine sulfate and chondroitin sulfate in the present invention share and can promote II type glue in human articular chondrocytes
The synthesis of former albumen, reduces chondrocyte dead, keeps anabolism and catabolic balance, the energy of cartilage cell epimatrix
Enough prevent and improve osteoarthritis, impaired cartilaginous tissue is repaired.
Owing to polypeptide mechanism of absorption has ten big features, under the soybean polypeptide effect in product of the present invention, first it show
Go out the effect of carrier, can be by glucosamine sulfate, chondroitin sulfate, soy peptide powder, powder of Radix Puerariae, calcium carbonate, particularly calcium etc.
The trace element useful to human body, adsorbs, pastes, is loaded on body;Secondly, play the effect of means of transport, can be by above-mentioned battalion
After foster material absorption is on body, then delivery is transported to each cell of human body, organ, tissue, is inhaled by human body together with body
Receive and utilize, playing the most different functions.
Owing to these act on, when polypeptide is yellow with plurality of Chinese the activity extract such as chondroitin sulfate, Radix Puerariae of integration of edible and medicinal herbs
After ketone, puerarin element organically coordinate so that micromolecule polypeptide, while being absorbed in time by human body, also promotes active Chinese drug component
The quick of material is absorbed, meanwhile, jointly acted on by number of ways same target spot (improve blood circulation, accelerate blood flow rate,
Improve blood oxygen ability) reach nutrition and curative effect with the purpose received.
Content of peptides more than 8% in product of the present invention, containing glucosamine more than 15%, containing chrondroitin more than 6%.
Advantages of the present invention:
1, raw material of the present invention be all health ministry approval be food and the article of medicine or new food former
Material, rich in nutritive value, belong to natural food, meet the related request of state food.
2, the present invention is with soybean polypeptide as primary raw material and one of carrier, and its wide material sources are cheap.To ammonium sulphate
Effect of base glucose and chondroitin sulfate plays promotion and synergism, then after scientific matching is prepared as health food,
Both possessed prevention and improved osteoarthritis, while impaired cartilaginous tissue is carried out repair, being easier to absorption of human body.
3, the present invention also added powder of Radix Puerariae so that product prevents and treat various types of bone joint being used for
Inflammation, as the positions such as knee joint, hip joint, spinal column, shoulder, hands, wrist and ankle joint and the osteoarthritis of general while
Also there is antithrombotic, the blood flow improving cardiovascular and cerebrovascular vessel and blood vessel microcirculation disturbance, blood fat reducing, regulation blood glucose, promote that enteral is double
Discrimination bacillus and the propagation of lactic acid bacteria, removing interior free yl, slow down aging etc. acts on, and is especially suitable for middle-aged and old health and Zhi
Sick.
4, product of the present invention is of value to absorption of human body, the nutritious polypeptide powder of addition, low to stomach function, absorption function
For shortcoming or slightly worse crowd, the product of the present invention is conducive to absorbing.
Detailed description of the invention
Embodiment 1
Below embodiments of the invention are described in detail, so that advantages and features of the invention are easier to be understood, thus
Protection scope of the present invention is made apparent clear and definite defining.
Embodiment 1:
Formula: glucosamine sulfate 25 g, chondroitin sulfate 22g, soy peptide powder 15g, powder of Radix Puerariae 10g, calcium carbonate 10g, micro-
Crystalline cellulose 5g, magnesium stearate 1g.
Preparation method: by above-mentioned glucosamine sulfate, chondroitin sulfate, soy peptide powder, powder of Radix Puerariae, calcium carbonate, crystallite
Cellulose, magnesium stearate is fully pulverized and mixed, stir after, make tablet, every 0.5g according to a conventional method.
Embodiment 2:
Formula: glucosamine sulfate 20g, chondroitin sulfate 20g, soy peptide powder 20g, powder of Radix Puerariae 5g, calcium carbonate 8g, crystallite are fine
Dimension element 3g, magnesium stearate 3g.
Preparation method: by above-mentioned glucosamine sulfate, chondroitin sulfate, soy peptide powder, powder of Radix Puerariae, calcium carbonate, crystallite
Cellulose, magnesium stearate is fully pulverized and mixed, stir after, make tablet, every 0.6g according to a conventional method.
Embodiment 3:
Formula: glucosamine sulfate 32g, chondroitin sulfate 32g, soy peptide powder 10g, powder of Radix Puerariae 8g, calcium carbonate 5g, crystallite are fine
Dimension element 2g, magnesium stearate 2g.
Preparation method: by above-mentioned glucosamine sulfate, chondroitin sulfate, soy peptide powder, powder of Radix Puerariae, calcium carbonate, crystallite
Cellulose, magnesium stearate is fully pulverized and mixed, stir after, make capsule, every 0.3g according to a conventional method.
Embodiment 4:
Formula: glucosamine sulfate 35g, chondroitin sulfate 35g, soy peptide powder 13g, powder of Radix Puerariae 8g, calcium carbonate 5g, crystallite are fine
Dimension element 2g, magnesium stearate 3g.
Preparation method: by above-mentioned glucosamine sulfate, chondroitin sulfate, soy peptide powder, powder of Radix Puerariae, calcium carbonate, crystallite
Cellulose, magnesium stearate is fully pulverized and mixed, stir after, make capsule, every 0.25g according to a conventional method.
Embodiment 5:
Formula: glucosamine sulfate 30g, chondroitin sulfate 30g, soy peptide powder 18g, powder of Radix Puerariae 6g, calcium carbonate 6g, crystallite are fine
Dimension element 4g, magnesium stearate 1g.
Preparation method: by above-mentioned glucosamine sulfate, chondroitin sulfate, soy peptide powder, powder of Radix Puerariae, calcium carbonate, crystallite
Cellulose, magnesium stearate is fully pulverized and mixed, stir after, make tablet, every 0.6g according to a conventional method.
Embodiment 6:
Formula: glucosamine sulfate 25g, chondroitin sulfate 30g, soy peptide powder 16g, powder of Radix Puerariae 7g, calcium carbonate 6g, crystallite are fine
Dimension element 3g, magnesium stearate 2g.
Preparation method: by above-mentioned glucosamine sulfate, chondroitin sulfate, soy peptide powder, powder of Radix Puerariae, calcium carbonate, crystallite
Cellulose, magnesium stearate is fully pulverized and mixed, stir after, make tablet, every 0.35g according to a conventional method.
Product clinical application effect
Fall ill 1: Huang, man, 54 years old, the assistant researcher that Guangxi District certain unit straight goes in for the study, in August, 2004 its left knee joint
Being diagnosed as osteoarthritis and implemented Minimally Invasive Surgery, postoperative 30 days, about 30 minutes these joints of moving every day just have ached
Sense, squats down when standing, can hear that there is sound in this joint, and continuous 3 months, period did not took any medicine, and sense of aching fails always
Eliminate.Thereafter take the tablet made by the formula of embodiment 5, twice daily, each 4, take after the meal, take one continuously
30 days courses for the treatment of, the state of an illness has taken a turn for the better, but inconspicuous, enters second course for the treatment of after withdrawing 5 days, and after taking 12 days, the state of an illness is slow
Slowly having taken a turn for the better, this joint aches sense alleviates and gradually obvious, and after taking 21 days, sense of aching substantially alleviates, and every day moves
Sense of aching for 60~90 minutes is inconspicuous, withdraws 5 days and enters back into the 3rd course for the treatment of, take the most continuously after having taken second course for the treatment of
Three courses for the treatment of, disappear to this joint aches sense of in March, 2016.
Fall ill 2: river, female, 83 years old, Yulin City of Guangxi Zhuang Autonomous villager, obtained waist hyperostosis through hospital diagnosis before 33 years
Raw disease, though through expectant treatment in many ways, but poor effect, it is unable to leave the bed time serious, hurt like hell, all the time flank pain when all
It is to paste some lenitive ointment or embrocate some medicated wine.From in February, 2013, on the basis of conventional therapy, hard
Hold and take product totally three courses for the treatment of (twice daily, each 4, take after the meal) doing piece agent by the formula of embodiment 2 every year,
Being separated by 5 days between two courses for the treatment of, the most i.e. in March, 2016, flank pain slowly alleviates, and symptom is substantially alleviated.
Fall ill 3: Lu, female, 48 years old, Nanning cause unit personnel.On August 15th, 2015 finds right shoulder joint
Pain (puies forward weight and trauma history), the most i.e. starts paste some lenitive ointment or embrocate some medicated wine, but produces effects
Little, evening grind turning sleeplessness in bed, hurt like hell.The tablet starting for 1st to make by the formula of embodiment 1 from JIUYUE in 2015,
Twice daily, each 4, take after the meal, (stop adhesive plaster during taking product and embrocate medicated wine) after taking 25 days continuously,
The state of an illness begins with and is taken a turn for the better, and when taking 30 days courses for the treatment of, pain substantially alleviates, and enters second course for the treatment of, work as clothes after withdrawing 5 days
After using the 8th day, pain disappears substantially, continues to take 30 days courses for the treatment of, is further continued for entering the 3rd course for the treatment of after withdrawing 5 days,
Cutting out after taking three courses for the treatment of continuously, the most i.e. in March, 2016, the most there is not pain in right shoulder joint.
Claims (3)
1. a peptide species D-glucosamine chrondroitin nutritious and healthy food, it is characterised in that: its raw material and parts by weight are:
Glucosamine sulfate 20~35 parts
Chondroitin sulfate 20~35 parts
Soy peptide powder 10~20 parts
Powder of Radix Puerariae 5~10 parts
Calcium carbonate 5~10 parts
Microcrystalline Cellulose 2~5 parts
Magnesium stearate 1~3 parts.
Polypeptide D-glucosamine chrondroitin nutritious and healthy food the most according to claim 1, it is characterised in that: its raw material and weight portion
Number is:
Glucosamine sulfate 25~30 parts
Chondroitin sulfate 25~30 parts
Soy peptide powder 15~20 parts
Powder of Radix Puerariae 5~10 parts
Calcium carbonate 5~10 parts
Microcrystalline Cellulose 2~5 parts
Magnesium stearate 1~3 parts.
Polypeptide D-glucosamine chrondroitin nutritious and healthy food the most according to claim 1, it is characterised in that: described polypeptide nutrition is good for
Health food is cooked piece agent or capsule.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610193657.3A CN105831738A (en) | 2016-03-31 | 2016-03-31 | Polypeptide glucosamine chondroitin nutritional health food |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610193657.3A CN105831738A (en) | 2016-03-31 | 2016-03-31 | Polypeptide glucosamine chondroitin nutritional health food |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105831738A true CN105831738A (en) | 2016-08-10 |
Family
ID=56596215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610193657.3A Pending CN105831738A (en) | 2016-03-31 | 2016-03-31 | Polypeptide glucosamine chondroitin nutritional health food |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105831738A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109601923A (en) * | 2018-08-10 | 2019-04-12 | 丽睿客信息科技(北京)有限公司 | Nutraceutical with calcium-enriching function |
CN112535706A (en) * | 2020-12-16 | 2021-03-23 | 解中胜 | Medicine and food dual-purpose powder for repairing joints and preparation method and application thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104939054A (en) * | 2014-03-26 | 2015-09-30 | 营养屋(成都)生物医药有限公司 | Health food capable of enhancing bone mineral density and immunity and preparation method of health food |
-
2016
- 2016-03-31 CN CN201610193657.3A patent/CN105831738A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104939054A (en) * | 2014-03-26 | 2015-09-30 | 营养屋(成都)生物医药有限公司 | Health food capable of enhancing bone mineral density and immunity and preparation method of health food |
Non-Patent Citations (1)
Title |
---|
王向东等: "《食品生物技术》", 30 September 2007, 东南大学出版社 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109601923A (en) * | 2018-08-10 | 2019-04-12 | 丽睿客信息科技(北京)有限公司 | Nutraceutical with calcium-enriching function |
CN112535706A (en) * | 2020-12-16 | 2021-03-23 | 解中胜 | Medicine and food dual-purpose powder for repairing joints and preparation method and application thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101248882B (en) | Nutrition food product with promoting health of bones and bone arthrosis | |
CN109452521B (en) | Auxiliary uric acid peptide reducing solid beverage, preparation method and application | |
CN102423487B (en) | Osteoarticular health-care composition and its application | |
CN106135890A (en) | A kind of alimentation composition contributing to bony articulation health | |
CN107319525A (en) | One kind fat-reducing fat reducing tailored version clinical nutrition formula and preparation method thereof | |
CN109123643A (en) | A kind of preparation method of cereal generation meal ball | |
CN106235311A (en) | A kind of compositions promoting skeletal system health and application thereof | |
CN106072651B (en) | It is a kind of with increasing bone density, composition of anti-inflammatory and analgesic effect and preparation method thereof | |
CN106723087A (en) | A kind of tablet containing kelp dietary fiber and preparation method thereof | |
CN104855994A (en) | Non-full nutritional formula food for patients with nephropathy | |
CN104839678A (en) | Medical formula food for people with nephrosis | |
CN106421757A (en) | Composition for assisting in treating gout and increasing bone density and application of composition | |
CN104839652A (en) | Postpartum recuperation medicine formula food for puerperas | |
CN105029400A (en) | Medical formula food for rheumatoid arthritis | |
CN104839659A (en) | Qi deficiency constitution medical formula food | |
CN106262809A (en) | A kind of bone density that strengthens alleviates the compositions of person in middle and old age's arthralgia | |
CN105831738A (en) | Polypeptide glucosamine chondroitin nutritional health food | |
CN104855963A (en) | Non-full nutritional formula food for delivery women in postpartum recuperation | |
CN105029390A (en) | Medical formula food for esophagus cancer | |
CN104207148A (en) | Cervical cancer full nutrient formula food | |
US20080312149A1 (en) | Health Food and Pharmaceutical Composition for Amelioration of Disease Induced by Metabolic Disorder in Cartilage | |
CN104839671A (en) | Medicine formula food for tonifying Yang | |
CN104839704A (en) | Yang invigorating non-total nutrient formula food | |
CN108815505A (en) | Improve the composition that middle-aged and the old's bone density and osteoarticular function avoid waist-leg from knotting | |
CN104855960A (en) | Non-complete nutrition formula food for wound infection following surgery and other emergency conditions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160810 |