CN105815527A - Sesame seed candy composition capable of relaxing bowel and preparation method thereof - Google Patents
Sesame seed candy composition capable of relaxing bowel and preparation method thereof Download PDFInfo
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- CN105815527A CN105815527A CN201610208772.3A CN201610208772A CN105815527A CN 105815527 A CN105815527 A CN 105815527A CN 201610208772 A CN201610208772 A CN 201610208772A CN 105815527 A CN105815527 A CN 105815527A
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- semen
- sesami nigrum
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- constipation
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- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 claims abstract description 18
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Botany (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses a sesame seed candy composition capable of relaxing bowel and a preparation method thereof. The sesame seed candy composition comprises the following components: semen raphani, konjac glucomannan, xylooligosaccharide, semen sesami nigrum, maltose, sesame seeds and white granulated sugar. On the premise of keeping the traditional flavor of sesame seed candy unchanged, the semen raphani, the konjac glucomannan, the xylooligosaccharide and the semen sesami nigrum as the functional component are added. The sesame seed candy composition is simple in process, convenient to make and high in nutrition value, can prevent and relieve the chronic functional constipation and is free of obvious side reaction.
Description
Technical field
The present invention relates to field of food preparation, particularly relate to a kind of prevention, constipation relieving, sesame candy compositions of tool function of relaxing bowel and preparation method thereof.
Background technology
Constipation (constipation) is one of most common symptom of digestive tract.Show as that defecation frequency reduces, feces is stiff and (or) difficult defecation.Defecation frequency reduces and refers to that weekly defecation is less than 3 times.Difficult defecation includes that defecation is laborious, it is difficult to discharge, defecation is felt not to the utmost, defecation is time-consuming and needs maneuver defecation assisting.
The epidemiological study that community-based population is carried out by China shows, China Adult chronic constipation prevalence is 4%-6%, and increases with the age and raise, and within more than 60 years old, crowd's chronic constipation prevalence may be up to 22%.Women prevalence is higher than male, and the ratio of men and women's prevalence is 1:1.22-1:4.56.Along with the change etc. of the aging of social population, modern life rhythm and dietary habit, the sickness rate of constipation substantially increases.It not only has a strong impact on the quality of life of modern, and close with the onset relation of colorectal cancer.
" Chinese Adult common anal and intestinal disease Epidemiological study " resident's bowl evacuation habit investigation display: bad bowl evacuation habit, such as variable interval defecation, defecation time sees books and newspapers, play mobile phone and cause defecation time prolongation, straining at stool is too quickly, ignores or suppresses awareness of defecation, is induction constipation and anorectal disease major reason.In food, cellulose intake is not enough, alteration of intestinal flora, and digestive tract power deficiency etc. is the common factors causing constipation.
The purpose of constipation therapy is relief of symptoms, recovers normal bowel power and defecation physiology function.Therefore, total principle is the Comprehensive Treatment of individuation, including recommending rational diet structure, sets up correct bowl evacuation habit, adjusts the Psychophysiological state etc. of patient.Reasonably dietary therapy is classified as one of Primary Care and first-selected measure both at home and abroad.For exploring functional constipation rational dietary therapy method, actively seek anorectal and the development opportunity of the big health field of lower digestive tract, Mayinglong Pharmaceutical Group Co., Ltd cooperates with authoritative institution expert, degree of depth excavation will be carried out by clinical proved recipe for many years, develop the loosening bowel to relieve constipation food with bowel relaxing functions.
The present invention is the food-sesame candy of function of relaxing bowel.China's snack Varieties is various, and sesame candy is due to without any chemical contamination, without any additive, is a kind of natural green food, very popular.A kind of loosening bowel to relieve constipation sesame candy in the case of meeting food basic function, loosening bowel to relieve constipation, complementary diets cellulose.Prevention and alleviation chronic functional constipation.Be suitable for toxin expelling, skin care, prevention is gentle defecate smooth, be hard and dry crowd.
Summary of the invention
Treatment to constipation both at home and abroad is all to start with from the Comprehensive Treatment mode such as life style and diet of adjustment, emphasizes symptomatic treatment and Grading treatment.The present invention is loosening bowel to relieve constipation food, caters to the development trend treating constipation both at home and abroad, and safety is high, and exact efficacy, formula is reasonable.
The party selects the Semen Raphani of medicine-food two-purpose, Semen Sesami, konjak glucomannan, and oligomeric xylose etc. is refined into loosening bowel to relieve constipation sesame candy food.
A kind of loosening bowel to relieve constipation sesame candy that the present invention provides, including following composition: Semen Raphani, konjak glucomannan, oligomeric xylose, Semen Sesami Nigrum, maltose, Semen Sesami Nigrum core and white sugar.
Preferably, above-mentioned loosening bowel to relieve constipation sesame candy, including the composition of following parts by weight:
Semen Raphani 0.1-50；
Konjak glucomannan 0.1-20；
Oligomeric xylose 0.1-20；
Semen Sesami Nigrum 1-50；
Maltose 30-50；
Semen Sesami Nigrum core 30-45；
White sugar 15-20.
It is highly preferred that above-mentioned loosening bowel to relieve constipation sesame candy, including the composition of following parts by weight:
Semen Raphani 5-20；
Konjak glucomannan 1.5-8；
Oligomeric xylose 1-5；
Semen Sesami Nigrum 25-35；
Maltose 20-40；
Semen Sesami Nigrum core 30-40；
White sugar 15-25.
The present invention also provides for the preparation method of above-mentioned loosening bowel to relieve constipation sesame candy, comprises the steps:
(1) Feedstock treating: take Semen Raphani, cleans, is dried, parch, pulverize as Semen Raphani powder, Semen Raphani powder, glucomannan, oligomeric xylose and Semen Sesami Nigrum are mixed, obtain mixture a；
(2) by after maltose, white sugar mix and blend, through heating up, concentrate, pull sugar, manufactured Board sugar;
(3) mixture a is joined in plate sugar, stirring, mix homogeneously, obtain mixture b;
(4), after again Semen Sesami Nigrum core being joined mixture b mixing thoroughly, play bar, cutting, obtain loosening bowel to relieve constipation sesame candy.
Preferably, step takes Semen Raphani in (1), cleans, washes the sand, is dried, parch, to have the intensification of cracker, shell brown, interior core zoom yellow, brittle for degree, low-temperature grinding, obtains Semen Raphani powder；
It is highly preferred that described baking temperature is 80 DEG C.
The method have the advantages that
1, in succession, have innovation, the Semen Raphani (parched) of selection, Semen Sesami Nigrum, glucomannan, the new formula of food promoting defecation that oligomeric xylose etc. forms, scientific and reasonable, unprecedented through retrieval, for exclusive innovation.These food a large amount of reports of Research Literature at all times: safe and reliable.There is promotion gastrointestinal motility, improve gastrointestinal tract dyskinesis, promote defecation, the anti-affirmative effect treated constipation, and have supplementary food fiber of copying, regulating intestinal canal flora.Make the effects such as probiotic bacteria hypertrophy.There is nourishing-to-relaxing, secret from originally controlling, the side effect such as dependency are produced without long-term taking.And select big, and Aloe, sennae, Semen Cassiae, the health food that Radix Polygoni Multiflori etc. is raw material, easily produce dependency, occur, for a long time after clothes, refusing to obey the cathartic dependency constipation of the most not defecation, cathartic need to being taken the most throughout one's life, protect and can not build counter being harmful to the health.
2, the color requirement of root Ju food of the present invention, with the Semen Sesami Nigrum coloring that color is the most shiny black, gives full play to the natural flavor of Semen Sesami Nigrum, has put forward sesame candy quality, add its mouthfeel, obtain and promote that defecation is good, double excellent effect that mouthfeel is good.Scientific formula is rigorous, exact efficacy has no side effect；Effect raw material of the present invention is all that raw material commonly used by food, has no side effect.Food additive used in the present invention all, in allowing range, belongs to safe food additive.
3, human experiment investigation report shows: a kind of loosening bowel to relieve constipation sesame candy of the present invention is evident in efficacy in terms of improving light moderate constipation symptom.Sesame candy group cure rate 7.0% of the present invention, effective 32.6%, effective 46.5%, total effective rate 86.0%.It follows that a kind of loosening bowel to relieve constipation sesame candy of the present invention is for the improvement of light moderate constipation patient symptom, definite effect, safety is good, and application prospect is extensive.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described, so that those skilled in the art can be better understood from the present invention and can be practiced, but illustrated embodiment is not as a limitation of the invention.As do not done specified otherwise, material composition consumption is parts by weight.
The loosening bowel to relieve constipation sesame candy that the present invention provides, including following composition: Semen Raphani, konjak glucomannan, oligomeric xylose, Semen Sesami Nigrum, maltose, Semen Sesami Nigrum core and white sugar.
A large amount of clinical report Semen Raphani (parched) treatment constipation truly have good effect, and Semen Raphani (parched) contains abundant oils and fats, and oils and fats has the function of Replenishing QI and nourishing YIN, loosening bowel to relieve constipation.Especially senile constipation is particularly suited the medicine to the illness.Experiment display: Semen Raphani difference extract remarkably promotes effect to Experimental Mice gastric emptying and Intestinal pushing, and Radix Raphani seed oil, Semen Raphani the water extracted immersing paste all have defecating feces excretion to mice with constipation, therefore think that Semen Raphani " circulation of qi promoting helps digestion " essence is to promote gastrointestinal motility.The fatty oil of Semen Sesami Nigrum seed is up to 55%, containing oleic acid (about 48%), linoleic acid (about 37%) etc. in oil.In addition seed coat is copied food fiber containing abundant therefore had good functions of loosening bowel relieving constipation.
Konjak glucomannan is that water solublity is copied food fiber, can absorb enough moisture at the intestines and stomach and expand, and volume increases, and forms colloidal state, so that feces becomes soft, easily by intestinal, it is easy to discharge；And there is promotion gastrointestinal motility effect, and shorten food residence time in gastrointestinal, in general, bread and cheese needs to empty from intestinal for 28 hours, and the food rich in dietary fiber has only to 14-16 hour, therefore has functions of loosening bowel relieving constipation.Oligomeric xylose is the preferable food of the beneficial bacteria of intestinal tract such as bifidus bacillus, therefore is also called prebiotics.There is compared with the soybean oligo saccharide used by usual people, oligofructose, oligomeric isomaltose etc. the advantage of uniqueness, it can selectively promote the proliferation activity of intestinal bifidobacteria, it increases bifidobacterium factor functional is 10-20 times of other polymerization saccharide, is that polymerization sugar apoplexy due to endogenous wind breeds one of the strongest kind of bacillus bifidus function.Bacillus bifidus utilizes oligomeric xylose, produces substantial amounts of short-chain fatty acid, can stimulate intestinal peristalsis promoting, promotes digestive tract power, increases feces wettability, and keeps certain osmotic pressure, thus anti-treats constipation.
Semen Sesami Nigrum granule, adds the fragrance of Semen Sesami, enriches sesame candy nutritive value, also improves shortcake and the mouthfeel of sesame candy.The present invention, on the premise of keeping sesame candy traditional properties constant, adds maltose and Semen Sesami Nigrum core, while strengthening sesame candy Semen Sesami fragrance, also enriches the nutritional labeling of sesame candy, adds sugariness and the shortcake of sesame candy, more meet the taste requirements of numerous people.
Above four tastes can be worked in coordination with generation and be promoted gastrointestinal motility, supplement food fiber of copying, regulating intestinal canal flora, promote effect of the probiotics hypertrophy such as bifidus bacillus, safe and reliable, have good defecating feces excretion.
A kind of loosening bowel to relieve constipation sesame candy that the present invention provides, plurality of active ingredients synergism, it is possible to prevent and alleviates chronic functional constipation, toxin expelling, skin care, prevention is gentle defecates freely, be hard and dry.The most commercially available commercial goods of mentioned component, such as Semen Raphani is purchased from Bozhou City Tang Dong Pharmaceutical Co., Ltd, konjak glucomannan is purchased from Hubei johnsen Rhizoma amorphophalli Science and Technology Ltd., oligomeric xylose is purchased from Shandong Longli Biology Science and Technology Co., Ltd.
The constituent of a kind of loosening bowel to relieve constipation sesame candy of embodiment of the present invention 1-10 and consumption:
| Embodiment | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
| Semen Raphani | 0.1 | 5 | 7 | 12.3 | 15 | 20 | 36.7 | 39.1 | 42.3 | 50 |
| Konjak glucomannan | 0.1 | 0.5 | 1.5 | 4.6 | 5.6 | 8 | 5.7 | 10 | 16 | 20 |
| Oligomeric xylose | 0.1 | 0.9 | 1 | 3.1 | 5 | 3.8 | 4.9 | 10 | 15 | 20 |
| Semen Sesami Nigrum | 1 | 6 | 25 | 32 | 30 | 35 | 20 | 32 | 46 | 50 3 --> |
| Maltose | 1 | 10 | 20 | 35 | 38 | 40 | 35 | 37 | 40 | 48 |
| Semen Sesami Nigrum core | 30 | 32 | 35 | 38 | 30 | 40 | 41 | 42 | 44 | 45 |
| White sugar | 15 | 15.7 | 15.9 | 18 | 20 | 25 | 19 | 19.3 | 19.8 | 20 |
The preparation process of above-mentioned a kind of loosening bowel to relieve constipation sesame candy is:
(1) take Semen Raphani, clean, wash the sand, 80 DEG C be dried, parch, to have the intensification of cracker, shell brown, interior core zoom yellow, brittle for degree, low-temperature grinding, takes the Semen Raphani powder after process, konjak glucomannan, oligomeric xylose, Semen Sesami Nigrum mix by a certain percentage, obtain mixture a.
(2) by after maltose, white sugar mix and blend, through heating up, concentrate, pull sugar, manufactured Board sugar.
(3) mixture a is joined in plate sugar, stirring, mix homogeneously, obtain mixture b.
(4), after again Semen Sesami Nigrum core being joined mixture b mixing thoroughly, beat bar, cut to obtain loosening bowel to relieve constipation sesame candy product.
A kind of loosening bowel to relieve constipation sesame candy that the present invention prepares in the case of meeting food basic function, loosening bowel to relieve constipation；Be suitable for prevention and alleviate chronic functional constipation crowd and toxin expelling, skin care, prevention is gentle defecate smooth, be hard and dry crowd.Now relevant result of study is reported as follows:
Human experiment investigation report
1, purpose
Selecting functional constipation crowd is experimenter, according to the diagnostic criteria of functional constipation in the Rome Ⅲ criteria that China's chronic constipation diagnosis and treatment guide (2013, Wuhan) is approved.Observe Semen Sesami Nigrum Semen Raphani fiber diet to the effectiveness of human body and safety.
2, method
(1) experimenter selects
1.1 inclusion criteria
Diagnostic criteria
The diagnostic criteria of functional constipation in the Rome Ⅲ criteria that employing " China's chronic constipation diagnosis and treatment guide (2013, Wuhan) " is approved.
1.1.1 following 2 or more than 2 must be included:
In 12 middle of the month in past, continue or accumulation at least 12 be all and has following 2 or more than 2 symptoms:
The defecation of at least 25% () feels laborious in every 4 defecations once
The defecation of at least 25% () is dry bulb excrement or hard excrement in every 4 defecations once
The defecation of at least 25% () has in every 4 defecations once to be felt not to the utmost
The defecation of at least 25% () has anorectal obstruction sense and (or) blocking sense in every 4 defecations once
The defecation of at least 25% () needs maneuver auxiliary (as assisted to support at the bottom of defecation, basin with finger) in every 4 defecations once
Defecation is less than 3 times weekly
1.1.2 without loose stool seldom occurs during cathartic
1.1.3 the diagnostic criteria of irritable bowel syndrome is not met
1.1.4 cardinal symptom observation index
" constipation symptom and the curative effect evaluation " formulated in Changchun is organized 2005 with reference to surgery branch of Chinese Medical Association Colon and rectum anus surgery；Constipation is marked by the record of feces character with evaluation reference " Bristol feces typing standard "；The description of feces character is according to Bristol feces character typing:
I type, pyreniform hard sphere;
II type, harden shape sausage sample;
III type, sausage sample, there is crack on surface;
IV type, smooth surface, soft sausage sample;
V type, soft bulk；
VI type, mushy stool;
VII type, watery stool.
Score as follows:
IV～VII type, counts 0 point;
III type, counts 1 point;
II type, counts 2 points;
I type, counts 3 points.
Type Ⅰ and the IIth type indicate constipation；IIIth type and the IVth type are preferable the most just shapes, and the especially the IVth type is the shape being easiest to defecation；V to the VIIth type then represents may diarrhoea.
1.2 exclusion standard
1. the unclear person of main suit.
2. carrying out surgical operation in 30 days causes constipation symptom to send out survivor.
3. recent difficult defecation person (colon cancer, serious enteritis, intestinal obstruction, inflammatory bowel etc.) is caused because of serious organic disease.
1.3 reject standard
1. inclusive criteria is not met, or the person that meets exclusion standard
The most once by the unused person of test product
3. without any keeper
1.4 come off (exiting) standard
1. experimenter's compliance is poor, it is impossible to eat the most according to quantity.
2. medicine or the food of other influences judgement are used.
3. experimenter is unwilling to proceed test, proposes bolter.
(2) tested material and method
2.1 tested material
Tested material: the loosening bowel to relieve constipation sesame candy (lot number: 20160106) of the present invention is provided by Mayinglong Pharmaceutical Group Co., Ltd.
Reference substance: common sesame candy (lot number: 20160106), profile packaging is consistent with tested material, Xiaogan Halvah and Rice Wine Co., Ltd. produce.
2.2 EXPERIMENTAL DESIGN and packet
This test-meal totally 122 example.Test-meal group: Semen Raphani Semen Sesami Nigrum high microsteping sesame candy 395 example, matched group: common sesame candy 26 example, men and women half and half.Require during test that experimenter does not change original dietary habit, if serious untoward reaction and adverse events occur, stop test immediately.
The dosage of 2.3 given the test agent and using method
Test-meal group: the loosening bowel to relieve constipation sesame candy that the embodiment of the present invention 1 ~ 10 prepares, each 3 pouches, every day 2 times, each 3, every day 2 times.
Matched group: common sesame candy, each 3 pouches, every day secondary.
The course for the treatment of: the most edible 7 days.
3, result judges
Test-meal group self compares before and after using test-meal, judges curative effect with compareing of blank group.
Curative effect determinate standard:
Formulate according to " new Chinese medicine guideline of clinical investigations " constipation criterion of therapeutical effect.
1. recovery from illness: stool is normal, other transference cures；
The most effective: constipation is obviously improved, interval time and just matter are close to normal；Or stool the most dry and infrequent defecation time is within 72 hours；
The most effective: the infrequent defecation time shortens 1 day, or the just dry and hard improvement of matter, and other symptoms all take a favorable turn；
Invalid: constipation and symptom thereof are all without improving.Medication observed curative effect after two weeks.
Total effective rate=(recovery from illness ten effective ten effective number of cases)/total number of cases × 100%)
The statistical disposition of test data
Test data is processed by applied statistics software SPSS19.0, and counting uses x2 inspection to carry out data process, and metering uses t inspection to carry out data process.Own control uses paired-sample t test, and two groups of means compare employing independent samples t test.The data of nonnormal distribution or heterogeneity of variance are used instead t inspection；But the logging data application rank test of the coefficient of variation too big (such as CV > 50%).
4, result
4.1 basic condition
The ordinary circumstance of table 1 test-meal crowd
| Project | Number of cases | Come off | Age | Male/female |
| Test-meal embodiment 1 sesame candy group | 40 examples | 0 example | 20-75 year | 20/20 |
| Test-meal embodiment 2 sesame candy group | 35 examples | 2 examples | 18-60 year | 17/18 |
| Test-meal embodiment 3 sesame candy group | 41 examples | 0 example | 30-75 year | 20/21 |
| Test-meal embodiment 4 sesame candy group | 43 examples | 0 example | 19-84 year | 17/26 |
| Test-meal embodiment 5 sesame candy group | 38 examples | 3 examples | 25-69 year | 18/20 |
| Test-meal embodiment 6 sesame candy group | 40 examples | 1 example | 22-74 year | 16/24 |
| Test-meal embodiment 7 sesame candy group | 33 examples | 0 example | 31-55 year | 16/17 |
| Test-meal embodiment 8 sesame candy group | 44 examples | 2 examples | 26-68 year | 18/26 |
| Test-meal embodiment 9 sesame candy group | 42 examples | 1 example | 20-58 year | 18/24 |
| Test-meal embodiment 10 sesame candy group | 39 examples | 3 examples | 19-84 year | 17/22 |
| Matched group | 26 examples | 0 example | 23-68 year | 9/17 |
| Amount to | 421 examples | 7 examples | 19-84 year | 26/43 |
4.2 efficacy analysis
The sesame candy group of the table 2 test-meal present invention and matched group curative effect statistical table
| Group | Number of cases | Recovery from illness | Effective | Effectively | Invalid | Total effective rate |
| Test-meal embodiment 1 sesame candy group | 40 examples | 2(5%) | 12(30%) | 18(45%) | 8(20%) | 80% |
| Test-meal embodiment 2 sesame candy group | 35 examples | 2(6.1%) | 10(30.3%) | 15(45.4%) | 6(18.2%) | 81.8% |
| Test-meal embodiment 3 sesame candy group | 41 examples | 3(7.3%) | 13(31.7%) | 20(48.8%) | 5(12.2%) | 87.8% 6 --> |
| Test-meal embodiment 4 sesame candy group | 43 examples | 5(11.6%) | 14(32.6%) | 20(46.5%) | 4(9.3%) | 90.7% |
| Test-meal embodiment 5 sesame candy group | 38 examples | 3(8.6%) | 12(34.3%) | 15(42.8) | 5(14.3%) | 85.7% |
| Test-meal embodiment 6 sesame candy group | 40 examples | 4(10.3%) | 13(33.3%) | 17(43.6%) | 5(12.8%) | 87.8% |
| Test-meal embodiment 7 sesame candy group | 33 examples | 2(6.1%) | 10(30.3%) | 15(45.4%) | 6(18.2%) | 81.8% |
| Test-meal embodiment 8 sesame candy group | 44 examples | 3(7.1%) | 12(28.6%) | 19(45.3%) | 8(19.0%) | 81% |
| Test-meal embodiment 9 sesame candy group | 42 examples | 2(4.9%) | 15(36.6%) | 16(39.0%) | 8(19.5%) | 80.5% |
| Test-meal embodiment 10 sesame candy group | 39 examples | 2(5.6%) | 14(38.9%) | 13(36.1%) | 7(19.4%) | 80.6% |
| Matched group | 26 | 1(3.8%) | 1(3.8%) | 3(11.5%) | 21(80.8%) | 19.2% |
Enumerate the efficacy analysis statistical data of the sesame candy group of test-meal embodiment 4 in detailed below:
Before and after the sesame candy group treatment of test-meal embodiment 4, symptom and sign integration total value and symptom and sign quantify integrated value change significant difference (P ＜ 0.05), and before and after the treatment of matched group common sesame candy, symptom and sign integration total value and symptom and sign quantify integrated value change not statistically significant.The sesame candy group of test-meal embodiment 4, compared with matched group, has significant difference (P ＜ 0.05).Result shows, sesame candy group of the present invention is in terms of symptom and sign improvement, and effect is preferable, and is substantially better than the common sesame candy of matched group.(be shown in Table 3, table 4)
Before and after table 3 treatment, the change of symptom and sign integration total value is compared
| Number of cases | Before treatment | After treatment | P value | |
| Sesame candy group | 43 | 8.84±3.63 | 4.93±3.85 | P ＜ 0.05 |
| Matched group | 26 | 7.50±3.37 | 7.23±3.40 | P ＞ 0.05 |
Before table 4 treatment, after treatment, symptom and sign quantifies integrated value change table
5, safety
Test-meal crowd has no untoward reaction.Semen Raphani, Semen Sesami Nigrum belongs to and is food and the article of medicine can apply to food；Glucomannan belongs to food；Oligomeric xylose belongs to food additive.The invention belongs to food, primary efficacy materials safety is legal, without any side effects to human body.
6, nutritional labeling
The loosening bowel to relieve constipation sesame candy that Example 4 prepares, records nutrient component meter as follows:
| Project | Every 100 grams | NVR% |
| Energy | 2018 kilojoules | 24% |
| Protein | 11.2 grams | 19% |
| Fat | 23.6 grams | 39% |
| Carbohydrate | 53.3 grams | 18% |
| Dietary fiber | 6.0 gram | 24% 7 --> |
| Sodium | 231 milligrams | 12% |
Embodiment described above is only the preferred embodiment lifted by absolutely proving the present invention, and protection scope of the present invention is not limited to this.The equivalent that those skilled in the art are made on the basis of the present invention substitutes or conversion, all within protection scope of the present invention.Protection scope of the present invention is as the criterion with claims.
Claims (6)
1. a loosening bowel to relieve constipation sesame candy, it is characterised in that include following composition: Semen Raphani, konjak glucomannan, oligomeric xylose, Semen Sesami Nigrum, maltose, Semen Sesami Nigrum core and white sugar.
Loosening bowel to relieve constipation sesame candy the most according to claim 1, it is characterised in that include the composition of following parts by weight:
Semen Raphani 0.1-50；
Konjak glucomannan 0.1-20；
Oligomeric xylose 0.1-20；
Semen Sesami Nigrum 1-50；
Maltose 30-50；
Semen Sesami Nigrum core 30-45；
White sugar 15-20.
Loosening bowel to relieve constipation sesame candy the most according to claim 1, it is characterised in that include the composition of following parts by weight:
Semen Raphani 5-20；
Konjak glucomannan 1.5-8；
Oligomeric xylose 1-5；
Semen Sesami Nigrum 25-35；
Maltose 20-40；
Semen Sesami Nigrum core 30-40；
White sugar 15-25.
4. the preparation method of the loosening bowel to relieve constipation sesame candy described in any one of claim 1-3, it is characterised in that comprise the steps:
(1) Feedstock treating: take Semen Raphani, cleans, is dried, parch, pulverize as Semen Raphani powder, Semen Raphani powder, glucomannan, oligomeric xylose and Semen Sesami Nigrum are mixed, obtain mixture a；
(2) by after maltose, white sugar mix and blend, through heating up, concentrate, pull sugar, manufactured Board sugar;
(3) mixture a is joined in plate sugar, stirring, mix homogeneously, obtain mixture b;
(4), after again Semen Sesami Nigrum core being joined mixture b mixing thoroughly, play bar, cutting, obtain loosening bowel to relieve constipation sesame candy.
Preparation method the most according to claim 4, it is characterised in that step takes Semen Raphani in (1), cleans, washes the sand, is dried, parch, to have the intensification of cracker, shell brown, interior core zoom yellow, brittle for degree, low-temperature grinding, obtains Semen Raphani powder.
Preparation method the most according to claim 5, it is characterised in that described baking temperature is 80 DEG C.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109770029A (en) * | 2017-11-13 | 2019-05-21 | 吉林农业大学 | It is a kind of using fungi polysaccharide as the sugar of functional components |
| CN113875873A (en) * | 2021-07-02 | 2022-01-04 | 华中农业大学 | Prebiotics sesame candy with good crispness and reduced sugar content and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109770029A (en) * | 2017-11-13 | 2019-05-21 | 吉林农业大学 | It is a kind of using fungi polysaccharide as the sugar of functional components |
| CN113875873A (en) * | 2021-07-02 | 2022-01-04 | 华中农业大学 | Prebiotics sesame candy with good crispness and reduced sugar content and preparation method thereof |
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Effective date of registration: 20191016 Address after: 430000 room 604, 6th floor, No. 8, Guannan 4th Road, Donghu New Technology Development Zone, Wuhan City, Hubei Province Applicant after: Wuhan Ma Yinglong Da Health Co., Ltd. Address before: 430064 No. 100, South Bay, Nanhu Lake, Wuhan, Hubei, Wuchang Applicant before: Mayinglong Pharmaceutical Group Co., Ltd. |
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