CN105796997A - Traditional Chinese medicine composition for treating patella arthritis - Google Patents

Traditional Chinese medicine composition for treating patella arthritis Download PDF

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CN105796997A
CN105796997A CN201610147152.3A CN201610147152A CN105796997A CN 105796997 A CN105796997 A CN 105796997A CN 201610147152 A CN201610147152 A CN 201610147152A CN 105796997 A CN105796997 A CN 105796997A
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chinese medicine
medicine composition
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赵海波
李伟
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Abstract

The invention discloses a traditional Chinese medicine composition for treating patella arthritis.Medicine for oral administration comprises cornu cervi degelatinatum, notopterygium roots, corn stigma, radix angelica sinensis, radix paeoniae alba, pangolin scales, leeches, roots of schisandra micrantha, roots of bidentate achyranthes, coix seeds, cortex acanthopanacis and rhizoma drynariae; medicine for external application comprises diverse wormwood herb, anise, native copper, radix gentianae macrophyllae, safflowers, radix clematidis, folium artemisiae argyi, white mustard seeds, radix aconiti kusnezoffii, garden balsam stems and Vaseline.All medicinal materials are under precise compatibility to jointly achieve the effects of dispelling wind, eliminating dampness, promoting blood circulation to remove blood stasis, relaxing muscles and tendons to activate collaterals and easing tension of joints.Oral administration and external application are combined, so that the medicinal effect directly reaches the focus, and the purposes of treating from the inside and the outside and treating both symptoms and root causes are achieved.When used for treating patella arthritis, the traditional Chinese medicine composition is accurate in curative effect, economical, high in cure rate, free of toxic and side effects and worthy of clinical application and popularization.

Description

A kind of Chinese medicine composition treating patellofemoral arthritis
Technical field
The invention belongs to the field of Chinese medicines, particularly relate to a kind of Chinese medicine composition treating patellofemoral arthritis.
Background technology
Patellofemoral arthritis is one of chief complaint now resulting in middle-aged and elderly people gonalgia, and its clinical symptoms is more complicated changeable, and mainly due to cartilage degradation, abrasion causes, cardinal symptom is arthralgia.Being embodied in anterior knee pain, after of short duration rest, pain perception can alleviate, but is as the prolongation of the course of disease, the remission time that pain needs is more and more longer, the number of times of the gonalgia increases, go downstairs or move be pain feel increase the weight of, patient's daily life is brought and has a strong impact on.
At present that the Therapeutic Method of primary disease is a lot, but it is mostly palliative treatment.Although expectant treatment patient's multipotency accepts, but relapse rate is high.Traditional non-steroidal drug is despite certain curative effect, but long-term taking untoward reaction is serious, and can not change the course of disease, even there will be the phenomenon of exacerbation of symptoms.And the Therapeutic Method of the intraarticular injection hyaluronate sodium in recent years occurred, expenses for medicine is higher, it is difficult to universal；There is again certain risk in arthrocsopic surgery treatment.Technology still has much room for improvement.Therefore, in recent years, we utilize the different pharmacological properties of various medical herbs, treat patellofemoral arthritis by Orally taken and externally medicine and achieve good curative effect.
Summary of the invention
Instant invention overcomes the deficiency existed in treatment patellofemoral arthritis at present, it is provided that a kind of evident in efficacy, have no side effect, cure rate is high and the outer External-applicationtraditional traditional Chinese medicinal for oral administration that not easily recurs.
The technical solution adopted in the present invention is:
A kind of Chinese medicine composition treating patellofemoral arthritis, it is characterised in that described Chinese medicine composition includes oral medicine and application compress,
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 20-30 gram, Rhizoma Et Radix Notopterygii 10-20 gram, Stigma Maydis 20-30 gram, Radix Angelicae Sinensis 10-20 gram, Radix Paeoniae Alba 10-20 gram, Squama Manis 5-10 gram, Hirudo 5-10 gram, Radix Schisandrae Micranthae 8-12 gram, Radix Achyranthis Bidentatae 5-10 gram, Semen Coicis 10-20 gram, Cortex Acanthopancis 8-12 gram, Rhizoma Drynariae 8-12 gram；
Application compress include: Herba Artemisiae Anomalae 10-20 gram, Fructus Anisi Stellati 10-20 gram, Pyritum 10-20 gram, Radix Gentianae Macrophyllae 10-20 gram, 5-10 gram of Flos Carthami, Radix Clematidis 5-10 gram, Folium Artemisiae Argyi 20-30 gram, Semen Sinapis Albae 8-12 gram, Radix Aconiti Kusnezoffii 8-12 gram, Herba speranskiae tuberculatae 10-20 gram, 50-80 gram of vaseline.
As a kind of prioritization scheme, described Chinese medicine composition includes oral medicine and application compress:
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 20 grams, Rhizoma Et Radix Notopterygii 10 grams, Stigma Maydis 20 grams, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 10 grams, Squama Manis 5 grams, Hirudo 5 grams, Radix Schisandrae Micranthae 8 grams, Radix Achyranthis Bidentatae 5 grams, Semen Coicis 10 grams, Cortex Acanthopancis 8 grams, Rhizoma Drynariae 8 grams；
Application compress include: Herba Artemisiae Anomalae 10 grams, Fructus Anisi Stellati 10 grams, Pyritum 10 grams, Radix Gentianae Macrophyllae 10 grams, 5 grams of Flos Carthami, Radix Clematidis 5 grams, Folium Artemisiae Argyi 20 grams, Semen Sinapis Albae 8 grams, Radix Aconiti Kusnezoffii 8 grams, Herba speranskiae tuberculatae 10 grams, 50 grams of vaseline.
As a kind of prioritization scheme, described Chinese medicine composition includes oral medicine and application compress:
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 22 grams, Rhizoma Et Radix Notopterygii 12 grams, Stigma Maydis 22 grams, Radix Angelicae Sinensis 12 grams, the Radix Paeoniae Alba 12 grams, Squama Manis 6 grams, Hirudo 6 grams, Radix Schisandrae Micranthae 8 grams, Radix Achyranthis Bidentatae 6 grams, Semen Coicis 13 grams, Cortex Acanthopancis 9 grams, Rhizoma Drynariae 9 grams；
Application compress include: Herba Artemisiae Anomalae 12 grams, Fructus Anisi Stellati 12 grams, Pyritum 12 grams, Radix Gentianae Macrophyllae 12 grams, 6 grams of Flos Carthami, Radix Clematidis 6 grams, Folium Artemisiae Argyi 22 grams, Semen Sinapis Albae 9 grams, Radix Aconiti Kusnezoffii 8 grams, Herba speranskiae tuberculatae 12 grams, 55 grams of vaseline.
As a kind of prioritization scheme, described Chinese medicine composition includes oral medicine and application compress:
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 24 grams, Rhizoma Et Radix Notopterygii 14 grams, Stigma Maydis 24 grams, Radix Angelicae Sinensis 14 grams, the Radix Paeoniae Alba 14 grams, Squama Manis 7 grams, Hirudo 7 grams, Radix Schisandrae Micranthae 9 grams, Radix Achyranthis Bidentatae 7 grams, Semen Coicis 14 grams, Cortex Acanthopancis 9 grams, Rhizoma Drynariae 9 grams；
Application compress include: Herba Artemisiae Anomalae 14 grams, Fructus Anisi Stellati 14 grams, Pyritum 14 grams, Radix Gentianae Macrophyllae 14 grams, 7 grams of Flos Carthami, Radix Clematidis 7 grams, Folium Artemisiae Argyi 24 grams, Semen Sinapis Albae 9 grams, Radix Aconiti Kusnezoffii 9 grams, Herba speranskiae tuberculatae 14 grams, 60 grams of vaseline.
As a kind of prioritization scheme, described Chinese medicine composition includes oral medicine and application compress:
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 26 grams, Rhizoma Et Radix Notopterygii 16 grams, Stigma Maydis 26 grams, Radix Angelicae Sinensis 16 grams, the Radix Paeoniae Alba 16 grams, Squama Manis 8 grams, Hirudo 8 grams, Radix Schisandrae Micranthae 10 grams, Radix Achyranthis Bidentatae 8 grams, Semen Coicis 16 grams, Cortex Acanthopancis 10 grams, Rhizoma Drynariae 10 grams；
Application compress include: Herba Artemisiae Anomalae 16 grams, Fructus Anisi Stellati 16 grams, Pyritum 16 grams, Radix Gentianae Macrophyllae 16 grams, 8 grams of Flos Carthami, Radix Clematidis 7 grams, Folium Artemisiae Argyi 26 grams, Semen Sinapis Albae 10 grams, Radix Aconiti Kusnezoffii 10 grams, Herba speranskiae tuberculatae 16 grams, 65 grams of vaseline.
As a kind of prioritization scheme, described Chinese medicine composition includes oral medicine and application compress:
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 28 grams, Rhizoma Et Radix Notopterygii 18 grams, Stigma Maydis 28 grams, Radix Angelicae Sinensis 18 grams, the Radix Paeoniae Alba 18 grams, Squama Manis 9 grams, Hirudo 9 grams, Radix Schisandrae Micranthae 11 grams, Radix Achyranthis Bidentatae 9 grams, Semen Coicis 18 grams, Cortex Acanthopancis 11 grams, Rhizoma Drynariae 11 grams；
Application compress include: Herba Artemisiae Anomalae 18 grams, Fructus Anisi Stellati 18 grams, Pyritum 18 grams, Radix Gentianae Macrophyllae 18 grams, 9 grams of Flos Carthami, Radix Clematidis 9 grams, Folium Artemisiae Argyi 28 grams, Semen Sinapis Albae 11 grams, Radix Aconiti Kusnezoffii 11 grams, Herba speranskiae tuberculatae 18 grams, 70 grams of vaseline.
As a kind of prioritization scheme, described Chinese medicine composition includes oral medicine and application compress:
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Stigma Maydis 30 grams, Radix Angelicae Sinensis 20 grams, the Radix Paeoniae Alba 20 grams, Squama Manis 10 grams, Hirudo 10 grams, Radix Schisandrae Micranthae 12 grams, Radix Achyranthis Bidentatae 10 grams, Semen Coicis 20 grams, Cortex Acanthopancis 12 grams, Rhizoma Drynariae 12 grams；
Application compress include: Herba Artemisiae Anomalae 20 grams, Fructus Anisi Stellati 20 grams, Pyritum 20 grams, Radix Gentianae Macrophyllae 20 grams, 10 grams of Flos Carthami, Radix Clematidis 10 grams, Folium Artemisiae Argyi 30 grams, Semen Sinapis Albae 12 grams, Radix Aconiti Kusnezoffii 12 grams, Herba speranskiae tuberculatae 20 grams, 80 grams of vaseline.
The instructions of taking of said medicine is: by Cornu Cervi Degelatinatum, Rhizoma Et Radix Notopterygii, Stigma Maydis, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Squama Manis, Hirudo, Radix Schisandrae Micranthae, Radix Achyranthis Bidentatae, Semen Coicis, Cortex Acanthopancis, Rhizoma Drynariae, after constant weight proportioning (adding and subtracting with disease) mixing, the traditionally method decocting system of fried Chinese medicine, every day potion, divide 2 decoction being taken warmly, within 15 days, be a course for the treatment of.Herba Artemisiae Anomalae, Fructus Anisi Stellati, Pyritum, Radix Gentianae Macrophyllae, Flos Carthami, Radix Clematidis, Folium Artemisiae Argyi, Semen Sinapis Albae 1, Radix Aconiti Kusnezoffii, Herba speranskiae tuberculatae are dried according to constant weight proportioning (adding and subtracting with disease) simultaneously and be crushed into powder, it is in harmonious proportion after uniformly with vaseline again and is applied in affected part, covering with hospital gauze is fixed on skin, drug of topical application every day 2 times.
The raw material Chinese medicine of said medicine:
Cornu Cervi Degelatinatum, salty in the mouth, cold in nature；Return liver, kidney channel.Having warming the kidney to activate YANG, benefit essence is enriched blood, effect of astringing to arrest bleeding.
Rhizoma Et Radix Notopterygii, acrid in the mouth is bitter, warm in nature；Return bladder, kidney channel.There is scattered exterior cold, wind-damp dispelling, profit effect such as joint, pain relieving.
Stigma Maydis, nature and flavor are sweet, light, nontoxic flat；Return spleen, kidney, bladder warp.There is diuresis expel the heat-evil, effect of suppressing the hyperactive liver function of gallbladder promoting.
Radix Angelicae Sinensis, acrid in the mouth, warm in nature；Return liver, the heart, spleen channel.There is replenishing and activating blood, effect of pain relieving intestine moistening.
The Radix Paeoniae Alba, bitter in the mouth, acid, cold nature；Return Liver Channel.There is the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, effect of suppressing the hyperactive liver and subsiding YANG.
Squama Manis, salty in the mouth, cold nature；Return liver, stomach warp.There is stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, search effect of wind and removing obstruction in channels.
Hirudo, bitter in the mouth is flat；Return Liver Channel.Having effect of removing blood stasis, the effect such as antithrombotic, anticoagulation is substantially.
Radix Schisandrae Micranthae, sweet in the mouth, hardship, property is put down；Return Liver Channel.There is inrigorating qi and promoting blood circulation, effect of channels sootheing and network vessel quickening.It is used for rheumatic arthritis, bones and muscles pain, traumatic injury, lumbar muscle strain, bronchitis, pulmonary tuberculosis cough spitting of blood.
Radix Achyranthis Bidentatae, bitter in the mouth, acid, property is put down；Return liver, kidney channel.There is nourishing the liver and kidney, bone and muscle strengthening, blood circulation promoting and blood stasis dispelling, effect of inducing diuresis for treating stranguria syndrome.
Semen Coicis, sweet in the mouth, cool in nature；Return spleen, lung, kidney channel.There is inducing diuresis to remove edema, the effect such as spleen invigorating is dried, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus.
Cortex Acanthopancis, acrid in the mouth, hardship, warm in nature；Return liver, kidney channel.There is the effects such as wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening.
Rhizoma Drynariae, bitter in the mouth, warm in nature；Return liver, kidney channel.There is the kidney invigorating bone strengthening, blood circulation promoting and blood stasis dispelling, the effect of pain relieving of curing the wound.
Herba Artemisiae Anomalae, acrid in the mouth, hardship, property is put down；Return lung, spleen channel.There is clearing away summer-heat and eliminating dampness, blood circulation promoting competent silt, effect of inducing menstruation to relieve menalgia.
Fructus Anisi Stellati, acrid in the mouth, warm in nature.Return liver,kidney,spleen, stomach warp.There is warming YANG to expel cold, effect of regulating QI to relieve pain.Cure mainly colic of cold type stomachache, chills and pain of the waist and kness, gastrofrigid vomiting, epigastric pain, the disturbance of lower legs due to pathogenic cold and dampness etc..
Pyritum, acrid in the mouth, hardship, property is put down；Return liver, kidney channel.There is eliminating stasis to stop pain, effect of reunion of bone.
Radix Gentianae Macrophyllae, bitter in the mouth, pungent, cold nature；Return stomach, liver, gallbladder meridian.There is expeling rheumatism, relaxing muscles and tendons and activating QI and blood in the collateral, clear profit deficiency-heat, effect of dampness removing jaundice eliminating.
Radix Clematidis, acrid in the mouth, salty, warm in nature；Return bladder warp.There is wind-damp dispelling, the meridian dredging, effect of stopping numbness pain.
Folium Artemisiae Argyi, bitter in the mouth, pungent, warm in nature；Return spleen, liver, kidney channel.There is vital energy regualting and blood circulation-promoting, by cold damp eliminating, effect of warming the meridian for stopping bleeding.
Semen Sinapis Albae, acrid in the mouth, warm in nature；Return lung meridian.There is warming the lung to eliminate phlegm, promoting the circulation of QI eliminating stagnation, effect of removing obstruction in the collateral to relieve pain.
Radix Aconiti Kusnezoffii, acrid in the mouth, hardship, hot in nature；GUIXIN, liver,kidney,spleen warp.There is expelling wind and removing dampness, effect of antalgic.
Herba speranskiae tuberculatae, sweet in the mouth, pungent, warm in nature；Return liver, kidney channel.Having a relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and dampness, promoting blood circulation and stopping pain, softening the hard mass disappears effect of painful abdominal mass.
Flos Carthami promoting blood circulation to restore menstrual flow, scattered silt pain relieving, for lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.The present invention mainly utilizes Flos Carthami effect of invigorating blood circulation to strengthen blood circulation and skin metabolism.
Vaseline is a kind of mineral wax, and it will not be absorbed by the skin, and can form one protecting film in skin surface, makes the moisture of skin not easily evaporate lost, and it is largely insoluble in water, can be attached on skin for a long time, therefore have good moistening effect.Vaseline of the present invention, as substrate, mainly utilizes its mediation medicated powder external application to use.
Motherland's medical science is thought, primary disease belongs to the categories such as " arthromyodynia ", " rheumatism involving the bone ", " knee joint numbness " of the traditional Chinese medical science."Nei Jing" points out " numbness, closes also ... wet three gas of wind and cold are assorted extremely, combined into numbness also ", it was shown that pain, the symptom such as limited of taking action.Most doctor thinks that its etiology and pathogenesis of primary disease mostly is liver and kidney deficiency, muscles and bones cervical carcinoma with cachexia, in addition wound, and strain, caused by wind-cold damp pathogen invasion and attack.Thus, discussing from the angle of numbness and control osteoarthritis, should catch primary disease is the feature of " deficiency in origin and excess in superficiality ".
In oral medicine of the present invention, Cornu Cervi Degelatinatum, Radix Achyranthis Bidentatae, Cortex Acanthopancis, osteomiosis complementary energy kidney invigorating and YANG supporting, bone and muscle strengthening, qi and blood tonifying, easing joint movement, improve immunity of organism resistance, be beneficial to the recovery of joint disease；Rhizoma Et Radix Notopterygii, Semen Coicis, Stigma Maydis, Squama Manis energy expelling wind and cold, damp eliminating of purging heat, reducing swelling and alleviating pain, play and dispel internal toxic dampness and heat, the effect of antiphlogistic antibacterial pain relieving；Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Schisandrae Micranthae, Hirudo energy replenishing and activating blood, channels sootheing and network vessel quickening, blood-activating analgetic, improve body blood microcirculation, strengthens local metabolic, reaches the purpose in Shu Li joint；The through sick institute of Radix Achyranthis Bidentatae priming, plays altogether and consolidates eliminating evil, dredge the merit of meridian and relieving pain.
In medicine for external use, Herba Artemisiae Anomalae, Folium Artemisiae Argyi, Herba speranskiae tuberculatae energy blood circulation promoting competent silt, wind-expelling pain-stopping, softening the hard mass disappear painful abdominal mass, accelerate the elimination of Patellar joint inflammation；Fructus Anisi Stellati, Radix Gentianae Macrophyllae warming YANG to expel cold, regulating QI to relieve pain, eliminate internal severe pathogenic cold, reaches the purpose of pain relieving；Pyritum, Flos Carthami blood circulation promoting and blood stasis dispelling, reunion of bone, promote that knitting and bone are newborn；Semen Sinapis Albae, Radix Clematidis, Radix Aconiti Kusnezoffii expelling wind and removing dampness, channels sootheing and network vessel quickening, eliminate joint pent-up pyretic toxicity, easing joint movement.Vaseline can be in harmonious proportion medicated powder preferably, makes medicine spread on skin affected part so that lasting medicine plays.All medicine compatibilities are superior, play expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling altogether, relaxing muscles and tendons and activating QI and blood in the collateral, effect of easing joint movement, oral administration and externally so that drug effect is gone directly focus, rule together inside and outside reaching, the purpose for the treatment of both the principal and secondary aspects of a disease, is used for treating patellofemoral arthritis determined curative effect, economical and practical, cure rate is high and has no side effect, clinic promotion and application.
For investigating the clinical efficacy of medicine of the present invention further, we have selected 100 example hospitals and out-patient carries out clinical trial, wherein male 61 example, women 39 example, oldest 71 years old, minimum 24 years old, 48 years old mean age；It is randomly divided into two groups to contrast, treatment group 50 example, each 25 examples of men and women, 47.6 years old mean age；Matched group 50 example, male 26 examples, female 24 example, 48.2 years old mean age；Two groups of patients, in sex, age, disease etc., compare through statistics and there was no significant difference (P > 0.05), have comparability.
Diagnostic criteria: typical case have a medical check-up finding be patella mill test (+)；There are mill sassafras sound, articular pain before knee joint.X-ray inspection often has hyperosteogeny in various degree, and x-ray axle position checks that visible patella rolls or subluxation.Lateral gap narrows, excessive long-term abrasion outside Patellar joint, can cause corresponding joint Subchondral bone sclerosis, visible " crescent moon sample " the osteosclerosis shadow of position, patella side X-ray film.
Therapeutic Method:
Treatment group: take Cornu Cervi Degelatinatum 26 grams, Rhizoma Et Radix Notopterygii 16 grams, Stigma Maydis 26 grams, Radix Angelicae Sinensis 16 grams, the Radix Paeoniae Alba 16 grams, Squama Manis 8 grams, Hirudo 8 grams, Radix Schisandrae Micranthae 10 grams, Radix Achyranthis Bidentatae 8 grams, Semen Coicis 16 grams, Cortex Acanthopancis 10 grams, Rhizoma Drynariae 10 grams (adding and subtracting with disease), take after decocting, every day, potion, divided 2 decoction being taken warmly.Herba Artemisiae Anomalae 16 grams, Fructus Anisi Stellati 16 grams, Pyritum 16 grams, Radix Gentianae Macrophyllae 16 grams, 8 grams of Flos Carthami, Radix Clematidis 7 grams, Folium Artemisiae Argyi 26 grams, Semen Sinapis Albae 10 grams, Radix Aconiti Kusnezoffii 10 grams, Herba speranskiae tuberculatae 16 grams (adding and subtracting with disease) are dried after being crushed into powder simultaneously, it is in harmonious proportion with 65 grams of vaseline and is uniformly externally applied to injury, drug of topical application every day 2 times.
Matched group adopts intraarticular injection method, and patient takes dorsal position, and in patella, lower edge recess is point of puncture, implantation glass acid sodium injection 2m1 after the routine disinfection of local, bends and stretches joint for several times after injection.Injection 1 time, 4 weeks is the l course for the treatment of weekly.Two groups, all with 4 weeks for 1 course for the treatment of, judge comprehensive therapeutic effect after 1 course for the treatment of.
Two groups all coordinate functional exercise, and one is muscle-training, mainly the muscular training of thigh.During as lain on the back, lower limb is stretched and lift, keep heel distance bed surface 15cm, adhere to 15 20s, put down rest, then lift, repetition training, can be from less to more.Also can in the hot-tempered portion of foot plus the exercise of appropriate weight.Also can proposing heel training, sustaining wall is stood, heel lift, toe stands, repetition training etc..Two is joint motion training, mainly to bend and stretch knee joint under not loading conditions, can coordinate training of squatting down.Functional exercise should adhere to that every day does, it is desirable to carries out under doctor regularly instructs.
Criterion of therapeutical effect:
Clinical cure: clinical symptoms, sign disappear, local is without tenderness, and activity is freely.
Effective: clinical symptom disappearance, sign is obviously improved, and pain substantially alleviates, and still has mild pain time movable.
Effective: clinical symptoms, sign are improved, weight time light during pain.
Invalid: symptom, sign are without improvement.
Efficacy result:
1. Clinical efficacy comparison:
After treatment, treatment group cures 38 examples, effective 6 examples, effective 3 examples, and invalid 3 examples, cure rate is 76.0%, and total effective rate reaches 94.0%；Matched group cures 21 examples, effective 8 examples, effective 13 examples, invalid 8 examples, and cure rate is 42.0%, and total effective rate is 84.0%；The symptoms such as treatment group Patellar joint pain, swelling, tenderness, improving action are substantially better than matched group, and two groups of results compare P < 0.05, and difference is statistically significant.Detailed results is in Table 1.
Curative effect comparision result table after 1: two group of case treatment of table
Group Number of cases Cure n (%) Effective n (%) Effective n (%) Invalid n (%) Total effective rate (%)
Treatment group 50 38(76.0) 6(12.0) 3(6.0) 3(6.0) 94.0
Matched group 50 21(42.0) 8(16.0) 13(26.0) 8(16.0) 84.0
2. untoward reaction is compared
In therapeutic process, all there is not obvious adverse reaction in two groups of patients.
Result shows, the present invention pure internal and external medicine medicine is used for treating patellofemoral arthritis and has the advantages such as clinical cure rate is high, evident in efficacy, have no side effect, and treatment by Chinese herbs is convenient and easy, economical and practical again, it is suitable for extensive patients application, is worth promoting in clinic.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine composition treating patellofemoral arthritis, choose oral medicine and application compress, wherein, oral medicine includes: Cornu Cervi Degelatinatum 20 grams, Rhizoma Et Radix Notopterygii 10 grams, Stigma Maydis 20 grams, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 10 grams, Squama Manis 5 grams, Hirudo 5 grams, Radix Schisandrae Micranthae 8 grams, Radix Achyranthis Bidentatae 5 grams, Semen Coicis 10 grams, Cortex Acanthopancis 8 grams, Rhizoma Drynariae 8 grams；Application compress include: Herba Artemisiae Anomalae 10 grams, Fructus Anisi Stellati 10 grams, Pyritum 10 grams, Radix Gentianae Macrophyllae 10 grams, 5 grams of Flos Carthami, Radix Clematidis 5 grams, Folium Artemisiae Argyi 20 grams, Semen Sinapis Albae 8 grams, Radix Aconiti Kusnezoffii 8 grams, Herba speranskiae tuberculatae 10 grams, 50 grams of vaseline.
Embodiment 2: a kind of Chinese medicine composition treating patellofemoral arthritis, choose oral medicine and application compress, wherein, oral medicine includes: Cornu Cervi Degelatinatum 22 grams, Rhizoma Et Radix Notopterygii 12 grams, Stigma Maydis 22 grams, Radix Angelicae Sinensis 12 grams, the Radix Paeoniae Alba 12 grams, Squama Manis 6 grams, Hirudo 6 grams, Radix Schisandrae Micranthae 8 grams, Radix Achyranthis Bidentatae 6 grams, Semen Coicis 13 grams, Cortex Acanthopancis 9 grams, Rhizoma Drynariae 9 grams；Application compress include: Herba Artemisiae Anomalae 12 grams, Fructus Anisi Stellati 12 grams, Pyritum 12 grams, Radix Gentianae Macrophyllae 12 grams, 6 grams of Flos Carthami, Radix Clematidis 6 grams, Folium Artemisiae Argyi 22 grams, Semen Sinapis Albae 9 grams, Radix Aconiti Kusnezoffii 8 grams, Herba speranskiae tuberculatae 12 grams, 55 grams of vaseline.
Embodiment 3: a kind of Chinese medicine composition treating patellofemoral arthritis, choose oral medicine and application compress, wherein, oral medicine includes: Cornu Cervi Degelatinatum 24 grams, Rhizoma Et Radix Notopterygii 14 grams, Stigma Maydis 24 grams, Radix Angelicae Sinensis 14 grams, the Radix Paeoniae Alba 14 grams, Squama Manis 7 grams, Hirudo 7 grams, Radix Schisandrae Micranthae 9 grams, Radix Achyranthis Bidentatae 7 grams, Semen Coicis 14 grams, Cortex Acanthopancis 9 grams, Rhizoma Drynariae 9 grams；Application compress include: Herba Artemisiae Anomalae 14 grams, Fructus Anisi Stellati 14 grams, Pyritum 14 grams, Radix Gentianae Macrophyllae 14 grams, 7 grams of Flos Carthami, Radix Clematidis 7 grams, Folium Artemisiae Argyi 24 grams, Semen Sinapis Albae 9 grams, Radix Aconiti Kusnezoffii 9 grams, Herba speranskiae tuberculatae 14 grams, 60 grams of vaseline.
Embodiment 4: a kind of Chinese medicine composition treating patellofemoral arthritis, choose oral medicine and application compress, wherein, oral medicine includes: Cornu Cervi Degelatinatum 26 grams, Rhizoma Et Radix Notopterygii 16 grams, Stigma Maydis 26 grams, Radix Angelicae Sinensis 16 grams, the Radix Paeoniae Alba 16 grams, Squama Manis 8 grams, Hirudo 8 grams, Radix Schisandrae Micranthae 10 grams, Radix Achyranthis Bidentatae 8 grams, Semen Coicis 16 grams, Cortex Acanthopancis 10 grams, Rhizoma Drynariae 10 grams；Application compress include: Herba Artemisiae Anomalae 16 grams, Fructus Anisi Stellati 16 grams, Pyritum 16 grams, Radix Gentianae Macrophyllae 16 grams, 8 grams of Flos Carthami, Radix Clematidis 7 grams, Folium Artemisiae Argyi 26 grams, Semen Sinapis Albae 10 grams, Radix Aconiti Kusnezoffii 10 grams, Herba speranskiae tuberculatae 16 grams, 65 grams of vaseline.
Embodiment 5: a kind of Chinese medicine composition treating patellofemoral arthritis, choose oral medicine and application compress, wherein, oral medicine includes: Cornu Cervi Degelatinatum 28 grams, Rhizoma Et Radix Notopterygii 18 grams, Stigma Maydis 28 grams, Radix Angelicae Sinensis 18 grams, the Radix Paeoniae Alba 18 grams, Squama Manis 9 grams, Hirudo 9 grams, Radix Schisandrae Micranthae 11 grams, Radix Achyranthis Bidentatae 9 grams, Semen Coicis 18 grams, Cortex Acanthopancis 11 grams, Rhizoma Drynariae 11 grams；Application compress include: Herba Artemisiae Anomalae 18 grams, Fructus Anisi Stellati 18 grams, Pyritum 18 grams, Radix Gentianae Macrophyllae 18 grams, 9 grams of Flos Carthami, Radix Clematidis 9 grams, Folium Artemisiae Argyi 28 grams, Semen Sinapis Albae 11 grams, Radix Aconiti Kusnezoffii 11 grams, Herba speranskiae tuberculatae 18 grams, 70 grams of vaseline.
Embodiment 6: a kind of Chinese medicine composition treating patellofemoral arthritis, choose oral medicine and application compress, wherein, oral medicine includes: Cornu Cervi Degelatinatum 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Stigma Maydis 30 grams, Radix Angelicae Sinensis 20 grams, the Radix Paeoniae Alba 20 grams, Squama Manis 10 grams, Hirudo 10 grams, Radix Schisandrae Micranthae 12 grams, Radix Achyranthis Bidentatae 10 grams, Semen Coicis 20 grams, Cortex Acanthopancis 12 grams, Rhizoma Drynariae 12 grams；Application compress include: Herba Artemisiae Anomalae 20 grams, Fructus Anisi Stellati 20 grams, Pyritum 20 grams, Radix Gentianae Macrophyllae 20 grams, 10 grams of Flos Carthami, Radix Clematidis 10 grams, Folium Artemisiae Argyi 30 grams, Semen Sinapis Albae 12 grams, Radix Aconiti Kusnezoffii 12 grams, Herba speranskiae tuberculatae 20 grams, 80 grams of vaseline.
Below by concrete case, the curative effect of medication of the present invention is verified further:
Case 1
Patient Yuanmou, female, 58 years old, double knee joint swelling pain, flexion-extension motion was limited, recurrent exerbation 1 year, increases the weight of 3 months.X-ray film shows: right knee space mild stenosis, and two tibia spinous process of tibia come to a point, the slight enlargement of Patellar joint, without red and swollen and heating, limitation of activity.Patient has no be clearly better through liniment and Chinese medicine and western medicine for oral administration.Recommend to take we's treatment through people.Take oral medicine Cornu Cervi Degelatinatum 20 grams, Rhizoma Et Radix Notopterygii 10 grams, Stigma Maydis 20 grams, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 10 grams, Squama Manis 5 grams, Hirudo 5 grams, Radix Schisandrae Micranthae 8 grams, Radix Achyranthis Bidentatae 5 grams, Semen Coicis 10 grams, Cortex Acanthopancis 8 grams, Rhizoma Drynariae 8 grams, take after decocting, every day 2 times；After being separately crushed into powder with Herba Artemisiae Anomalae 10 grams, Fructus Anisi Stellati 10 grams, Pyritum 10 grams, Radix Gentianae Macrophyllae 10 grams, 5 grams of Flos Carthami, Radix Clematidis 5 grams, Folium Artemisiae Argyi 20 grams, Semen Sinapis Albae 8 grams, Radix Aconiti Kusnezoffii 8 grams, 10 grams of drying of Herba speranskiae tuberculatae, it is in harmonious proportion with 50 grams of vaseline and is uniformly externally applied to injury, drug of topical application every day 2 times.After medication 2 weeks, patient's Patellar joint swelling pain substantially alleviates, and movable takes a turn for the better, and after 1 course for the treatment of, joint recovers normal, can normally upper downstairs and the action such as go down on one's kness of squatting down, clinical cure.
Case 2
Dong patient, man, 32 years old.Patient is owing to often playing basketball, and knee abrasion is relatively big, engenders that the frequent lower limb of stair activity felt like jelly later, the symptom such as to go down on one's knees in spite of oneself.Even knee hurt like hell when half squatting position, after light activity, occur under knee clear and melodious " clickly " sound.Examination in hospital diagnosis is patellofemoral arthritis.Once took western medicine and had no positive effect, thus attempted to we's Chinese medicine conditioning and treating.Take Cornu Cervi Degelatinatum 26 grams, Rhizoma Et Radix Notopterygii 16 grams, Stigma Maydis 26 grams, Radix Angelicae Sinensis 16 grams, the Radix Paeoniae Alba 16 grams, Squama Manis 8 grams, Hirudo 8 grams, Radix Schisandrae Micranthae 10 grams, Radix Achyranthis Bidentatae 8 grams, Semen Coicis 16 grams, Cortex Acanthopancis 10 grams, Rhizoma Drynariae 10 grams, take after decocting, every day 2 times；Separately take Herba Artemisiae Anomalae 16 grams, after Fructus Anisi Stellati 16 grams, Pyritum 16 grams, Radix Gentianae Macrophyllae 16 grams, 8 grams of Flos Carthami, Radix Clematidis 7 grams, Folium Artemisiae Argyi 26 grams, Semen Sinapis Albae 10 grams, Radix Aconiti Kusnezoffii 10 grams, 16 grams of drying of Herba speranskiae tuberculatae are crushed into powder, it is in harmonious proportion with 65 grams of vaseline and is uniformly externally applied to injury, drug of topical application every day 2 times.After half course for the treatment of of medication, patient articular's pain and swelling are obviously improved, stair activity energy activity freely, pain of having stood up after only squatting down for a long time, then continue and treated with 2 weeks, after 1 course for the treatment of, all diseases all disappear, and patient recovers normal.
Case 3
Patient Song, man, 55 years old.Patient, because suffering from cold after carrying articles from the storeroom fatigue the year before, causes two knee joint Patellar joint congestion and swelling pains, difficulty in walking, increases the weight of day by day, particularly in upper downstairs and when knee bears pressure, and two knee joint hurt like hells.Once having an injection in certain hospital and Chinese and western drugs and application compress are administered orally, and failing to respond to any medical treatment, symptom is still increasing the weight of, then with we's treatment under friend recommendation.Checking and find that patient two knee joint swelling is obvious, local skin temperature increases, the right tenderness of patella periphery, bends and stretches difficulty, and the warm fear of cold of happiness, right morning is stiff, difficulty in walking.Take Cornu Cervi Degelatinatum 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Stigma Maydis 30 grams, Radix Angelicae Sinensis 20 grams, the Radix Paeoniae Alba 20 grams, Squama Manis 10 grams, Hirudo 10 grams, Radix Schisandrae Micranthae 12 grams, Radix Achyranthis Bidentatae 10 grams, Semen Coicis 20 grams, Cortex Acanthopancis 12 grams, Rhizoma Drynariae 12 grams, oral after decocting, every day twice.Separately take Herba Artemisiae Anomalae 20 grams, after Fructus Anisi Stellati 20 grams, Pyritum 20 grams, Radix Gentianae Macrophyllae 20 grams, 10 grams of Flos Carthami, Radix Clematidis 10 grams, Folium Artemisiae Argyi 30 grams, Semen Sinapis Albae 12 grams, Radix Aconiti Kusnezoffii 12 grams, 20 grams of drying of Herba speranskiae tuberculatae are crushed into powder, it is in harmonious proportion with 80 grams of vaseline and is uniformly externally applied to injury, drug of topical application every day 2 times.After medication 2 weeks, swelling and pain substantially alleviate, and continue medication 2 weeks, and pain and swelling is wholly absent, and freely, patient cures in activity.

Claims (7)

1. the Chinese medicine composition treating patellofemoral arthritis, it is characterised in that described Chinese medicine composition includes oral medicine and application compress,
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 20-30 gram, Rhizoma Et Radix Notopterygii 10-20 gram, Stigma Maydis 20-30 gram, Radix Angelicae Sinensis 10-20 gram, Radix Paeoniae Alba 10-20 gram, Squama Manis 5-10 gram, Hirudo 5-10 gram, Radix Schisandrae Micranthae 8-12 gram, Radix Achyranthis Bidentatae 5-10 gram, Semen Coicis 10-20 gram, Cortex Acanthopancis 8-12 gram, Rhizoma Drynariae 8-12 gram；
Application compress include: Herba Artemisiae Anomalae 10-20 gram, Fructus Anisi Stellati 10-20 gram, Pyritum 10-20 gram, Radix Gentianae Macrophyllae 10-20 gram, 5-10 gram of Flos Carthami, Radix Clematidis 5-10 gram, Folium Artemisiae Argyi 20-30 gram, Semen Sinapis Albae 8-12 gram, Radix Aconiti Kusnezoffii 8-12 gram, Herba speranskiae tuberculatae 10-20 gram, 50-80 gram of vaseline.
2. Chinese medicine composition according to claim 1, it is characterised in that described Chinese medicine composition includes oral medicine and application compress,
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 20 grams, Rhizoma Et Radix Notopterygii 10 grams, Stigma Maydis 20 grams, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 10 grams, Squama Manis 5 grams, Hirudo 5 grams, Radix Schisandrae Micranthae 8 grams, Radix Achyranthis Bidentatae 5 grams, Semen Coicis 10 grams, Cortex Acanthopancis 8 grams, Rhizoma Drynariae 8 grams；
Application compress include: Herba Artemisiae Anomalae 10 grams, Fructus Anisi Stellati 10 grams, Pyritum 10 grams, Radix Gentianae Macrophyllae 10 grams, 5 grams of Flos Carthami, Radix Clematidis 5 grams, Folium Artemisiae Argyi 20 grams, Semen Sinapis Albae 8 grams, Radix Aconiti Kusnezoffii 8 grams, Herba speranskiae tuberculatae 10 grams, 50 grams of vaseline.
3. Chinese medicine composition according to claim 1, it is characterised in that described Chinese medicine composition includes oral medicine and application compress,
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 22 grams, Rhizoma Et Radix Notopterygii 12 grams, Stigma Maydis 22 grams, Radix Angelicae Sinensis 12 grams, the Radix Paeoniae Alba 12 grams, Squama Manis 6 grams, Hirudo 6 grams, Radix Schisandrae Micranthae 8 grams, Radix Achyranthis Bidentatae 6 grams, Semen Coicis 13 grams, Cortex Acanthopancis 9 grams, Rhizoma Drynariae 9 grams；
Application compress include: Herba Artemisiae Anomalae 12 grams, Fructus Anisi Stellati 12 grams, Pyritum 12 grams, Radix Gentianae Macrophyllae 12 grams, 6 grams of Flos Carthami, Radix Clematidis 6 grams, Folium Artemisiae Argyi 22 grams, Semen Sinapis Albae 9 grams, Radix Aconiti Kusnezoffii 8 grams, Herba speranskiae tuberculatae 12 grams, 55 grams of vaseline.
4. Chinese medicine composition according to claim 1, it is characterised in that described Chinese medicine composition includes oral medicine and application compress,
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 24 grams, Rhizoma Et Radix Notopterygii 14 grams, Stigma Maydis 24 grams, Radix Angelicae Sinensis 14 grams, the Radix Paeoniae Alba 14 grams, Squama Manis 7 grams, Hirudo 7 grams, Radix Schisandrae Micranthae 9 grams, Radix Achyranthis Bidentatae 7 grams, Semen Coicis 14 grams, Cortex Acanthopancis 9 grams, Rhizoma Drynariae 9 grams；
Application compress include: Herba Artemisiae Anomalae 14 grams, Fructus Anisi Stellati 14 grams, Pyritum 14 grams, Radix Gentianae Macrophyllae 14 grams, 7 grams of Flos Carthami, Radix Clematidis 7 grams, Folium Artemisiae Argyi 24 grams, Semen Sinapis Albae 9 grams, Radix Aconiti Kusnezoffii 9 grams, Herba speranskiae tuberculatae 14 grams, 60 grams of vaseline.
5. Chinese medicine composition according to claim 1, it is characterised in that described Chinese medicine composition includes oral medicine and application compress,
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 26 grams, Rhizoma Et Radix Notopterygii 16 grams, Stigma Maydis 26 grams, Radix Angelicae Sinensis 16 grams, the Radix Paeoniae Alba 16 grams, Squama Manis 8 grams, Hirudo 8 grams, Radix Schisandrae Micranthae 10 grams, Radix Achyranthis Bidentatae 8 grams, Semen Coicis 16 grams, Cortex Acanthopancis 10 grams, Rhizoma Drynariae 10 grams；
Application compress include: Herba Artemisiae Anomalae 16 grams, Fructus Anisi Stellati 16 grams, Pyritum 16 grams, Radix Gentianae Macrophyllae 16 grams, 8 grams of Flos Carthami, Radix Clematidis 7 grams, Folium Artemisiae Argyi 26 grams, Semen Sinapis Albae 10 grams, Radix Aconiti Kusnezoffii 10 grams, Herba speranskiae tuberculatae 16 grams, 65 grams of vaseline.
6. Chinese medicine composition according to claim 1, it is characterised in that described Chinese medicine composition includes oral medicine and application compress,
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 28 grams, Rhizoma Et Radix Notopterygii 18 grams, Stigma Maydis 28 grams, Radix Angelicae Sinensis 18 grams, the Radix Paeoniae Alba 18 grams, Squama Manis 9 grams, Hirudo 9 grams, Radix Schisandrae Micranthae 11 grams, Radix Achyranthis Bidentatae 9 grams, Semen Coicis 18 grams, Cortex Acanthopancis 11 grams, Rhizoma Drynariae 11 grams；
Application compress include: Herba Artemisiae Anomalae 18 grams, Fructus Anisi Stellati 18 grams, Pyritum 18 grams, Radix Gentianae Macrophyllae 18 grams, 9 grams of Flos Carthami, Radix Clematidis 9 grams, Folium Artemisiae Argyi 28 grams, Semen Sinapis Albae 11 grams, Radix Aconiti Kusnezoffii 11 grams, Herba speranskiae tuberculatae 18 grams, 70 grams of vaseline.
7. Chinese medicine composition according to claim 1, it is characterised in that described Chinese medicine composition includes oral medicine and application compress,
Wherein, oral medicine includes: Cornu Cervi Degelatinatum 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Stigma Maydis 30 grams, Radix Angelicae Sinensis 20 grams, the Radix Paeoniae Alba 20 grams, Squama Manis 10 grams, Hirudo 10 grams, Radix Schisandrae Micranthae 12 grams, Radix Achyranthis Bidentatae 10 grams, Semen Coicis 20 grams, Cortex Acanthopancis 12 grams, Rhizoma Drynariae 12 grams；
Application compress include: Herba Artemisiae Anomalae 20 grams, Fructus Anisi Stellati 20 grams, Pyritum 20 grams, Radix Gentianae Macrophyllae 20 grams, 10 grams of Flos Carthami, Radix Clematidis 10 grams, Folium Artemisiae Argyi 30 grams, Semen Sinapis Albae 12 grams, Radix Aconiti Kusnezoffii 12 grams, Herba speranskiae tuberculatae 20 grams, 80 grams of vaseline.
CN201610147152.3A 2016-03-15 2016-03-15 Traditional Chinese medicine composition for treating patella arthritis Pending CN105796997A (en)

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CN1706441A (en) * 2005-04-27 2005-12-14 杨文锋 Arthralgia treating plaster
CN101181568A (en) * 2007-12-04 2008-05-21 朱惠芬 Traditional chinese medicine preparation for curing osteoproliferation as well as arthrosis ache
CN103585296A (en) * 2013-10-18 2014-02-19 陈欣 Externally applied preparation for treating patella injury, and preparation method thereof
CN105031137A (en) * 2015-08-02 2015-11-11 成都市飞龙水处理技术研究所 Orally-taken medicine for treating chondromalacia patellae and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1706441A (en) * 2005-04-27 2005-12-14 杨文锋 Arthralgia treating plaster
CN101181568A (en) * 2007-12-04 2008-05-21 朱惠芬 Traditional chinese medicine preparation for curing osteoproliferation as well as arthrosis ache
CN103585296A (en) * 2013-10-18 2014-02-19 陈欣 Externally applied preparation for treating patella injury, and preparation method thereof
CN105031137A (en) * 2015-08-02 2015-11-11 成都市飞龙水处理技术研究所 Orally-taken medicine for treating chondromalacia patellae and preparation method thereof

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Application publication date: 20160727