CN105796809A - Antibacterial adhesive plaster and preparation method thereof - Google Patents
Antibacterial adhesive plaster and preparation method thereof Download PDFInfo
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- CN105796809A CN105796809A CN201610246360.9A CN201610246360A CN105796809A CN 105796809 A CN105796809 A CN 105796809A CN 201610246360 A CN201610246360 A CN 201610246360A CN 105796809 A CN105796809 A CN 105796809A
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention relates to an antibacterial adhesive plaster and a preparation method thereof. The antibacterial adhesive plaster is prepared from, by mass, 25-38 parts of natural rubber, 10-22 parts of ethylene-vinyl acetate copolymer, 20-32 parts of ground calcium carbonate, 0.5-1.5 parts of dioctyl phthalate, 2-7 parts of hydroxyl silicone oil, 3-10 parts of pine tar, 4-10 parts of white factice, 5-15 parts of iron oxide red, 0.2-0.6 part of dioctyl sebacate, 5-10 parts of herba houttuyniae, 5-10 parts of decumbent bugle herb, 5-10 parts of lovely hemsleya roots, 5-10 parts of rhizoma polygoni cuspidati, 5-10 parts of herba schizonepetae and 5-10 parts of corm of waternut. The adhesive plaster has good tensile strength and bonding strength, very high antibacterial and bacteriostatic effects are achieved simultaneously, invasion of outside bacteria to wounds can be effectively blocked, and good elimination and treatment effects on ulcerative carbuncle sore pain, wound swelling, wound toxin and the like are achieved.
Description
Technical field
The present invention relates to medical material tech field, particularly relate to a kind of antibacterial rubber plaster and preparation method thereof.
Background technology
Rubber plaster is a kind of drug packing material, and general employing pure cotton cloth is the end, with natural rubber and pure matter zinc oxide
For raw material.The selected material of rubber plaster, outward appearance is exquisite, the refrigerant fragrance of abnormal smells from the patient, is widely used in operation and stumbles wound, fixes dressing and lead
The wrapping of pipe etc. and reinforcing, paste comfortable, painless when removing, permanent tack, noresidue when removing, without skin wet oil and
Allergic phenomena, for parts of body, is the optimum selection of the auxiliary material of family of hospital.
The making raw material of current existing Medical adhesive plaster is natural rubber and zinc oxide etc..Although preparing with these materials
The rubber plaster obtained has been able to meet general use needs, but it is antibacterial and bacteriostasis property is poor, and does not have treatment
The effects such as ulcerative carbuncle swells and ache, removing toxic substances.
Summary of the invention
Solve the technical problem that: poor for existing rubber plaster antibacterial effect and do not have treatment ulcerative carbuncle swell and ache, detoxify
Etc. the shortcoming of effect, the present invention provides a kind of antibacterial rubber plaster and preparation method thereof.
Technical scheme: a kind of antibacterial rubber plaster, containing following component in terms of mass parts: natural rubber 25～38 parts, ethylene-
Acetate ethylene copolymer 10～22 parts, ground calcium carbonate 20～32 parts, dioctyl phthalate 0.5～1.5 parts, hydroxy silicon oil
2～7 parts, pine tar 3～10 parts, white factice 4～10 parts, iron oxide red 5～15 parts, dioctyl sebacate 0.2～0.6 part, fish
Raw meat grass 5～10 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5～10 parts, Radix Hemsleyae Macrospermae 5～10 parts, Rhizoma Polygoni Cuspidati 5～10 parts, Herba Schizonepetae 5～10 parts, Corm Eleocharitis 5～10 parts.
The antibacterial rubber plaster of one described above, containing following component in terms of mass parts: natural rubber 28～34 parts, second
Alkene-acetate ethylene copolymer 12～20 parts, ground calcium carbonate 23～29 parts, dioctyl phthalate 0.8～1.3 parts, hydroxyl
Silicone oil 3～6 parts, pine tar 4～9 parts, white factice 5～9 parts, iron oxide red 7～14 parts, dioctyl sebacate 0.3～0.5 part,
Herba Houttuyniae 5～8 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5～8 parts, Radix Hemsleyae Macrospermae 5～8 parts, Rhizoma Polygoni Cuspidati 6～9 parts, Herba Schizonepetae 6～9 parts, Corm Eleocharitis 6～9 parts.
The antibacterial rubber plaster of one described above, containing following component in terms of mass parts: natural rubber 30 parts, ethylene-vinegar
Acid ethylene copolymer 14 parts, ground calcium carbonate 25 parts, dioctyl phthalate 0.9 part, hydroxy silicon oil 4 parts, pine tar 5 parts,
White factice 6 parts, iron oxide red 9 parts, dioctyl sebacate 0.35 part, Herba Houttuyniae 6 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 6 parts, Radix Hemsleyae Macrospermae 6 parts, Rhizoma Polygoni Cuspidati 7 parts,
Herba Schizonepetae 7 parts, Corm Eleocharitis 7 parts.
The antibacterial rubber plaster of one described above, containing following component in terms of mass parts: natural rubber 31 parts, ethylene-vinegar
Acid ethylene copolymer 16 parts, ground calcium carbonate 27 parts, dioctyl phthalate 1.1 parts, hydroxy silicon oil 4.5 parts, pine tar 6.5
Part, white factice 7 parts, iron oxide red 10 parts, dioctyl sebacate 0.4 part, Herba Houttuyniae 6.5 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 6.5 parts, Radix Hemsleyae Macrospermae 6.5
Part, Rhizoma Polygoni Cuspidati 7.5 parts, Herba Schizonepetae 7.5 parts, Corm Eleocharitis 7.5 parts.
The preparation method of a kind of antibacterial rubber plaster described above, the step of this preparation method is as follows:
The first step: by natural rubber, ethylene-vinyl acetate copolymer, ground calcium carbonate, dioctyl phthalate, hydroxyl silicon
Oil, pine tar, iron oxide red, dioctyl sebacate put in agitator, rotating speed be 200～240r/min, temperature be 80～
Stir 10～30min at 100 DEG C, obtain colloid；
Second step: decoct after Herba Houttuyniae, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Radix Hemsleyae Macrospermae, Rhizoma Polygoni Cuspidati, Herba Schizonepetae, Corm Eleocharitis mixing, add 6～8 times for the first time
Amount water, decocts 1.5～2.5h, and second time adds 4～6 times amount water, decocts 1～2h, merges twice decocting liquid, decocting liquid is used sheet frame mistake
Filter filters, and obtains filtrate；
3rd step: adding ethanol in the filtrate that second step obtains, ethanol weight is 2 times of filtrate, filters after standing 20h, filter
Liquid reclaims ethanol, is then condensed into paste, obtains ointment；
4th step: after the ointment mix homogeneously that the colloid first step obtained and the 3rd step obtain, is pressed into thin slice in mill,
Add white factice, be coated in after stirring on calico, obtain antibacterial rubber plaster.
Rotating speed when mixing in the first step described above is 220r/min, temperature is 90 DEG C, mixing time is 20min.
Adding 7 times amount water in second step described above for the first time, decoct 2h, second time adds 5 times amount water, decocts
1.5h。
Beneficial effect: antibacterial rubber plaster of one that the present invention provides and preparation method thereof, this rubber plaster has good drawing
Stretch intensity and adhesion strength, there is the strongest antibacterial and bacteriostasis efficacy simultaneously, it is possible to effectively stop that wound is invaded by extraneous antibacterial
Attack, and ulcerative carbuncle is swollen and ache, wound swelling, wound toxin etc. have and well eliminate and therapeutic effect.
Detailed description of the invention
Embodiment 1
A kind of antibacterial rubber plaster, containing following component in terms of mass parts: natural rubber 25 parts, ethylene-vinyl acetate copolymer 10
Part, ground calcium carbonate 20 parts, dioctyl phthalate 0.5 part, hydroxy silicon oil 2 parts, pine tar 3 parts, white factice 4 parts, oxidation
Iron oxide red 5 parts, dioctyl sebacate 0.2 part, Herba Houttuyniae 5 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5 parts, Radix Hemsleyae Macrospermae 5 parts, Rhizoma Polygoni Cuspidati 5 parts, Herba Schizonepetae 5 parts, Corm Eleocharitis 5
Part.
A kind of preparation method of antibacterial rubber plaster, the step of this preparation method is as follows:
The first step: by natural rubber, ethylene-vinyl acetate copolymer, ground calcium carbonate, dioctyl phthalate, hydroxyl silicon
Oil, pine tar, iron oxide red, dioctyl sebacate put in agitator, rotating speed be 200r/min, temperature be to stir at 80 DEG C
10min, obtains colloid；
Second step: decoct after Herba Houttuyniae, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Radix Hemsleyae Macrospermae, Rhizoma Polygoni Cuspidati, Herba Schizonepetae, Corm Eleocharitis mixing, add 6 times amount for the first time
Water, decocts 1.5h, and second time adds 4 times amount water, decocts 1h, merges twice decocting liquid, is filtered by decocting liquid flame filter press, obtains
Filtrate；
3rd step: adding ethanol in the filtrate that second step obtains, ethanol weight is 2 times of filtrate, filters after standing 20h, filter
Liquid reclaims ethanol, is then condensed into paste, obtains ointment；
4th step: after the ointment mix homogeneously that the colloid first step obtained and the 3rd step obtain, is pressed into thin slice in mill,
Add white factice, be coated in after stirring on calico, obtain antibacterial rubber plaster.
Embodiment 2
A kind of antibacterial rubber plaster, containing following component in terms of mass parts: natural rubber 38 parts, ethylene-vinyl acetate copolymer 22
Part, ground calcium carbonate 32 parts, dioctyl phthalate 1.5 parts, hydroxy silicon oil 7 parts, pine tar 10 parts, white factice 10 parts, oxygen
Change iron oxide red 15 parts, dioctyl sebacate 0.6 part, Herba Houttuyniae 10 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 10 parts, Radix Hemsleyae Macrospermae 10 parts, Rhizoma Polygoni Cuspidati 10 parts, Herba Schizonepetae 10
Part, Corm Eleocharitis 10 parts.
A kind of preparation method of antibacterial rubber plaster, the step of this preparation method is as follows:
The first step: by natural rubber, ethylene-vinyl acetate copolymer, ground calcium carbonate, dioctyl phthalate, hydroxyl silicon
Oil, pine tar, iron oxide red, dioctyl sebacate put in agitator, rotating speed be 240r/min, temperature be to stir at 100 DEG C
Mix 30min, obtain colloid；
Second step: decoct after Herba Houttuyniae, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Radix Hemsleyae Macrospermae, Rhizoma Polygoni Cuspidati, Herba Schizonepetae, Corm Eleocharitis mixing, add 8 times amount for the first time
Water, decocts 2.5h, and second time adds 6 times amount water, decocts 2h, merges twice decocting liquid, is filtered by decocting liquid flame filter press, obtains
Filtrate；
3rd step: adding ethanol in the filtrate that second step obtains, ethanol weight is 2 times of filtrate, filters after standing 20h, filter
Liquid reclaims ethanol, is then condensed into paste, obtains ointment；
4th step: after the ointment mix homogeneously that the colloid first step obtained and the 3rd step obtain, is pressed into thin slice in mill,
Add white factice, be coated in after stirring on calico, obtain antibacterial rubber plaster.
Embodiment 3
A kind of antibacterial rubber plaster, containing following component in terms of mass parts: natural rubber 34 parts, ethylene-vinyl acetate copolymer 20
Part, ground calcium carbonate 29 parts, dioctyl phthalate 1.3 parts, hydroxy silicon oil 6 parts, pine tar 9 parts, white factice 9 parts, oxidation
Iron oxide red 14 parts, dioctyl sebacate 0.5 part, Herba Houttuyniae 8 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 8 parts, Radix Hemsleyae Macrospermae 8 parts, Rhizoma Polygoni Cuspidati 9 parts, Herba Schizonepetae 9 parts, Corm Eleocharitis 9
Part.
A kind of preparation method of antibacterial rubber plaster, the step of this preparation method is as follows:
The first step: by natural rubber, ethylene-vinyl acetate copolymer, ground calcium carbonate, dioctyl phthalate, hydroxyl silicon
Oil, pine tar, iron oxide red, dioctyl sebacate put in agitator, rotating speed be 220r/min, temperature be to stir at 90 DEG C
20min, obtains colloid；
Second step: decoct after Herba Houttuyniae, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Radix Hemsleyae Macrospermae, Rhizoma Polygoni Cuspidati, Herba Schizonepetae, Corm Eleocharitis mixing, add 7 times amount for the first time
Water, decocts 2h, and second time adds 5 times amount water, decocts 1.5h, merges twice decocting liquid, is filtered by decocting liquid flame filter press, obtains
Filtrate；
3rd step: adding ethanol in the filtrate that second step obtains, ethanol weight is 2 times of filtrate, filters after standing 20h, filter
Liquid reclaims ethanol, is then condensed into paste, obtains ointment；
4th step: after the ointment mix homogeneously that the colloid first step obtained and the 3rd step obtain, is pressed into thin slice in mill,
Add white factice, be coated in after stirring on calico, obtain antibacterial rubber plaster.
Embodiment 4
A kind of antibacterial rubber plaster, containing following component in terms of mass parts: natural rubber 30 parts, ethylene-vinyl acetate copolymer 14
Part, ground calcium carbonate 25 parts, dioctyl phthalate 0.9 part, hydroxy silicon oil 4 parts, pine tar 5 parts, white factice 6 parts, oxidation
Iron oxide red 9 parts, dioctyl sebacate 0.35 part, Herba Houttuyniae 6 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 6 parts, Radix Hemsleyae Macrospermae 6 parts, Rhizoma Polygoni Cuspidati 7 parts, Herba Schizonepetae 7 parts, Corm Eleocharitis 7
Part.
A kind of preparation method of antibacterial rubber plaster, the step of this preparation method is as follows:
The first step: by natural rubber, ethylene-vinyl acetate copolymer, ground calcium carbonate, dioctyl phthalate, hydroxyl silicon
Oil, pine tar, iron oxide red, dioctyl sebacate put in agitator, rotating speed be 220r/min, temperature be to stir at 90 DEG C
20min, obtains colloid；
Second step: decoct after Herba Houttuyniae, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Radix Hemsleyae Macrospermae, Rhizoma Polygoni Cuspidati, Herba Schizonepetae, Corm Eleocharitis mixing, add 7 times amount for the first time
Water, decocts 2h, and second time adds 5 times amount water, decocts 1.5h, merges twice decocting liquid, is filtered by decocting liquid flame filter press, obtains
Filtrate；
3rd step: adding ethanol in the filtrate that second step obtains, ethanol weight is 2 times of filtrate, filters after standing 20h, filter
Liquid reclaims ethanol, is then condensed into paste, obtains ointment；
4th step: after the ointment mix homogeneously that the colloid first step obtained and the 3rd step obtain, is pressed into thin slice in mill,
Add white factice, be coated in after stirring on calico, obtain antibacterial rubber plaster.
Embodiment 5
A kind of antibacterial rubber plaster, containing following component in terms of mass parts: natural rubber 31 parts, ethylene-vinyl acetate copolymer 16
Part, ground calcium carbonate 27 parts, dioctyl phthalate 1.1 parts, hydroxy silicon oil 4.5 parts, pine tar 6.5 parts, white factice 7 parts,
Iron oxide red 10 parts, dioctyl sebacate 0.4 part, Herba Houttuyniae 6.5 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 6.5 parts, Radix Hemsleyae Macrospermae 6.5 parts, Rhizoma Polygoni Cuspidati 7.5 parts, chaste tree
7.5 parts of mustard, Corm Eleocharitis 7.5 parts.
A kind of preparation method of antibacterial rubber plaster, the step of this preparation method is as follows:
The first step: by natural rubber, ethylene-vinyl acetate copolymer, ground calcium carbonate, dioctyl phthalate, hydroxyl silicon
Oil, pine tar, iron oxide red, dioctyl sebacate put in agitator, rotating speed be 220r/min, temperature be to stir at 90 DEG C
20min, obtains colloid；
Second step: decoct after Herba Houttuyniae, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Radix Hemsleyae Macrospermae, Rhizoma Polygoni Cuspidati, Herba Schizonepetae, Corm Eleocharitis mixing, add 7 times amount for the first time
Water, decocts 2h, and second time adds 5 times amount water, decocts 1.5h, merges twice decocting liquid, is filtered by decocting liquid flame filter press, obtains
Filtrate；
3rd step: adding ethanol in the filtrate that second step obtains, ethanol weight is 2 times of filtrate, filters after standing 20h, filter
Liquid reclaims ethanol, is then condensed into paste, obtains ointment；
4th step: after the ointment mix homogeneously that the colloid first step obtained and the 3rd step obtain, is pressed into thin slice in mill,
Add white factice, be coated in after stirring on calico, obtain antibacterial rubber plaster.
The technical performance index of the antibacterial rubber plaster of above-described embodiment 1～embodiment 5, its testing result is as follows:
Above the embodiment of the present invention is described in detail, for one of ordinary skill in the art, implements according to the present invention
The thought of example, the most all will change, and in sum, this specification content should not be managed
Solve as limitation of the present invention.
Claims (7)
1. an antibacterial rubber plaster, it is characterised in that containing following component in terms of mass parts: natural rubber 25～38 parts, ethylene-
Acetate ethylene copolymer 10～22 parts, ground calcium carbonate 20～32 parts, dioctyl phthalate 0.5～1.5 parts, hydroxy silicon oil
2～7 parts, pine tar 3～10 parts, white factice 4～10 parts, iron oxide red 5～15 parts, dioctyl sebacate 0.2～0.6 part, fish
Raw meat grass 5～10 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5～10 parts, Radix Hemsleyae Macrospermae 5～10 parts, Rhizoma Polygoni Cuspidati 5～10 parts, Herba Schizonepetae 5～10 parts, Corm Eleocharitis 5～10 parts.
The antibacterial rubber plaster of one the most according to claim 1, it is characterised in that containing following component in terms of mass parts: natural
Rubber 28～34 parts, ethylene-vinyl acetate copolymer 12～20 parts, ground calcium carbonate 23～29 parts, dioctyl phthalate
0.8～1.3 part, hydroxy silicon oil 3～6 parts, pine tar 4～9 parts, white factice 5～9 parts, iron oxide red 7～14 parts, decanedioic acid two
Pungent fat 0.3～0.5 part, Herba Houttuyniae 5～8 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5～8 parts, Radix Hemsleyae Macrospermae 5～8 parts, Rhizoma Polygoni Cuspidati 6～9 parts, Herba Schizonepetae 6～9 parts, water chestnut
Shepherd's purse 6～9 parts.
The antibacterial rubber plaster of one the most according to claim 1, it is characterised in that containing following component in terms of mass parts: natural
Rubber 30 parts, ethylene-vinyl acetate copolymer 14 parts, ground calcium carbonate 25 parts, dioctyl phthalate 0.9 part, hydroxyl silicon
Oil 4 parts, pine tar 5 parts, white factice 6 parts, iron oxide red 9 parts, dioctyl sebacate 0.35 part, Herba Houttuyniae 6 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 6 parts,
Radix Hemsleyae Macrospermae 6 parts, Rhizoma Polygoni Cuspidati 7 parts, Herba Schizonepetae 7 parts, Corm Eleocharitis 7 parts.
The antibacterial rubber plaster of one the most according to claim 1, it is characterised in that containing following component in terms of mass parts: natural
Rubber 31 parts, ethylene-vinyl acetate copolymer 16 parts, ground calcium carbonate 27 parts, dioctyl phthalate 1.1 parts, hydroxyl silicon
Oil 4.5 parts, pine tar 6.5 parts, white factice 7 parts, iron oxide red 10 parts, dioctyl sebacate 0.4 part, Herba Houttuyniae 6.5 parts, muscles and bones
Grass 6.5 parts, Radix Hemsleyae Macrospermae 6.5 parts, Rhizoma Polygoni Cuspidati 7.5 parts, Herba Schizonepetae 7.5 parts, Corm Eleocharitis 7.5 parts.
5. the preparation method of a kind of antibacterial rubber plaster described in claim 1, it is characterised in that the step of this preparation method is as follows:
The first step: by natural rubber, ethylene-vinyl acetate copolymer, ground calcium carbonate, dioctyl phthalate, hydroxyl silicon
Oil, pine tar, iron oxide red, dioctyl sebacate put in agitator, rotating speed be 200～240r/min, temperature be 80～
Stir 10～30min at 100 DEG C, obtain colloid；
Second step: decoct after Herba Houttuyniae, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Radix Hemsleyae Macrospermae, Rhizoma Polygoni Cuspidati, Herba Schizonepetae, Corm Eleocharitis mixing, add 6～8 times for the first time
Amount water, decocts 1.5～2.5h, and second time adds 4～6 times amount water, decocts 1～2h, merges twice decocting liquid, decocting liquid is used sheet frame mistake
Filter filters, and obtains filtrate；
3rd step: adding ethanol in the filtrate that second step obtains, ethanol weight is 2 times of filtrate, filters after standing 20h, filter
Liquid reclaims ethanol, is then condensed into paste, obtains ointment；
4th step: after the ointment mix homogeneously that the colloid first step obtained and the 3rd step obtain, is pressed into thin slice in mill,
Add white factice, be coated in after stirring on calico, obtain antibacterial rubber plaster.
The preparation method of a kind of antibacterial rubber plaster the most according to claim 5, it is characterised in that: the described first step mixes
Time rotating speed be 220r/min, temperature be 90 DEG C, mixing time be 20min.
The preparation method of a kind of antibacterial rubber plaster the most according to claim 5, it is characterised in that: in described second step first
Secondary addition 7 times amount water, decocts 2h, and second time adds 5 times amount water, decocts 1.5h.
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| CN201610246360.9A CN105796809A (en) | 2016-04-20 | 2016-04-20 | Antibacterial adhesive plaster and preparation method thereof |
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| CN201610246360.9A CN105796809A (en) | 2016-04-20 | 2016-04-20 | Antibacterial adhesive plaster and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107304296A (en) * | 2016-08-19 | 2017-10-31 | 如皋长江科技产业有限公司 | A kind of nontoxic antibacterial plasticine and preparation method thereof |
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| CN102875872A (en) * | 2012-09-24 | 2013-01-16 | 吴江市信许塑料鞋用配套有限公司 | Preparation method for wear-resistant antibacterial sole material |
| CN104323526A (en) * | 2014-11-18 | 2015-02-04 | 中国人民解放军总后勤部军需装备研究所 | Wear-resistant heat-vulcanized rubber shoes |
| CN104436322A (en) * | 2014-11-10 | 2015-03-25 | 苏州蔻美新材料有限公司 | Medical adhesive plaster and preparation method thereof |
| CN104844843A (en) * | 2014-02-17 | 2015-08-19 | 如皋市启润运动用品有限公司 | Golf ball bar rubber grip |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102875872A (en) * | 2012-09-24 | 2013-01-16 | 吴江市信许塑料鞋用配套有限公司 | Preparation method for wear-resistant antibacterial sole material |
| CN104844843A (en) * | 2014-02-17 | 2015-08-19 | 如皋市启润运动用品有限公司 | Golf ball bar rubber grip |
| CN104436322A (en) * | 2014-11-10 | 2015-03-25 | 苏州蔻美新材料有限公司 | Medical adhesive plaster and preparation method thereof |
| CN104323526A (en) * | 2014-11-18 | 2015-02-04 | 中国人民解放军总后勤部军需装备研究所 | Wear-resistant heat-vulcanized rubber shoes |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107304296A (en) * | 2016-08-19 | 2017-10-31 | 如皋长江科技产业有限公司 | A kind of nontoxic antibacterial plasticine and preparation method thereof |
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Application publication date: 20160727 |