CN105795290A - Hericium erinaceus compound beverage having alpha-amylase inhibitory activity and preparation method thereof - Google Patents
Hericium erinaceus compound beverage having alpha-amylase inhibitory activity and preparation method thereof Download PDFInfo
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- CN105795290A CN105795290A CN201610183850.9A CN201610183850A CN105795290A CN 105795290 A CN105795290 A CN 105795290A CN 201610183850 A CN201610183850 A CN 201610183850A CN 105795290 A CN105795290 A CN 105795290A
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- hericium erinaceus
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Links
- 240000000588 Hericium erinaceus Species 0.000 title claims abstract description 76
- 235000007328 Hericium erinaceus Nutrition 0.000 title claims abstract description 76
- 102000004139 alpha-Amylases Human genes 0.000 title claims abstract description 37
- 108090000637 alpha-Amylases Proteins 0.000 title claims abstract description 37
- 229940024171 alpha-amylase Drugs 0.000 title claims abstract description 37
- 230000002401 inhibitory effect Effects 0.000 title claims abstract description 27
- 235000013361 beverage Nutrition 0.000 title claims abstract description 24
- 150000001875 compounds Chemical class 0.000 title claims abstract description 24
- 238000002360 preparation method Methods 0.000 title claims description 17
- 239000000284 extract Substances 0.000 claims abstract description 72
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 52
- 108010013296 Sericins Proteins 0.000 claims abstract description 50
- 241001105098 Angelica keiskei Species 0.000 claims abstract description 46
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 38
- 241000220317 Rosa Species 0.000 claims abstract description 24
- 238000000034 method Methods 0.000 claims abstract description 14
- 239000000796 flavoring agent Substances 0.000 claims abstract description 8
- 150000005846 sugar alcohols Chemical class 0.000 claims abstract description 6
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 4
- 235000013615 non-nutritive sweetener Nutrition 0.000 claims abstract description 4
- 244000309464 bull Species 0.000 claims description 70
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 60
- 239000006228 supernatant Substances 0.000 claims description 43
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- 239000007788 liquid Substances 0.000 claims description 41
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- 239000000843 powder Substances 0.000 claims description 33
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- 238000002156 mixing Methods 0.000 claims description 13
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- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 claims description 10
- MVORZMQFXBLMHM-QWRGUYRKSA-N Gly-His-Lys Chemical compound NCCCC[C@@H](C(O)=O)NC(=O)[C@@H](NC(=O)CN)CC1=CN=CN1 MVORZMQFXBLMHM-QWRGUYRKSA-N 0.000 claims description 10
- 108010038983 glycyl-histidyl-lysine Proteins 0.000 claims description 10
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- 239000000126 substance Substances 0.000 claims description 5
- 230000002378 acidificating effect Effects 0.000 claims description 4
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N coumarin Chemical compound C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 claims description 4
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- QMVPMAAFGQKVCJ-SNVBAGLBSA-N (R)-(+)-citronellol Natural products OCC[C@H](C)CCC=C(C)C QMVPMAAFGQKVCJ-SNVBAGLBSA-N 0.000 claims description 3
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- 239000005792 Geraniol Substances 0.000 claims description 3
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- 238000003809 water extraction Methods 0.000 description 10
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid group Chemical group C(CC(O)(C(=O)O)CC(=O)O)(=O)O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 9
- 230000001629 suppression Effects 0.000 description 7
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- 229920002472 Starch Polymers 0.000 description 3
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- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 3
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- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 108010011485 Aspartame Proteins 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 2
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- 235000010357 aspartame Nutrition 0.000 description 2
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- 150000002482 oligosaccharides Chemical class 0.000 description 2
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- 235000021122 unsaturated fatty acids Nutrition 0.000 description 2
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- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 description 1
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
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- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
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- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
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- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 235000001497 healthy food Nutrition 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
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- 230000001717 pathogenic effect Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/68—Acidifying substances
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Non-Alcoholic Beverages (AREA)
Abstract
The present invention discloses a hericium erinaceus compound functional beverage having an alpha-amylase inhibitory activity. The compound functional beverage consists of the following components in parts by weight: 0.003-0.01 part of hericium erinaceus extract, 0.05-0.5 part of angelica keiskei extract, 0.003-0.01 part of sericin peptide extract, 2-8 parts of sugar alcohol, 0.000-0.003 part of low-calorie sweetener, 0.1-0.3 part of sour agent, 1-5 parts of rose flower essences and 88-96 parts of water. The present invention also discloses a method of the hericium erinaceus compound functional beverage having the alpha-amylase inhibitory activity. The hericium erinaceus compound functional beverage has multiple health-care functions of moistening skin and beautifying features, nourishing stomach and strengthening spleen, inhibiting alpha-amylase inhibitory activity and improving human body immune system, fragrance of rose flowers and clear and sweet mouthfeel of hericium erinaceus and angelica keiskei. The nutritional value and organoleptic flavor and quality of the beverage are enhanced, and at the same time, the beverage is suitable for the consumptions of people with diabetes or obese people and other special populations.
Description
Technical field
The invention belongs to food technology field, relate to a kind of compounding beverage and preparation method thereof, be specifically related to a kind of tool
The Hericium erinaceus (Bull. Ex Fr.) Pers. having α-amylase inhibitory activity compounds drinks and preparation method thereof.
Background technology
In intestinal, starch digestion needs three kinds of main alpha-glucosidases to participate in: first pancreatic alpha-amylase (HPA) will form sediment
Powder is hydrolyzed into the oligosaccharide of short straight or branched, oligosaccharide subsequently by maltose-glucosidase (MGAM) and sucrose-
Isomaltase (SI) is hydrolyzed to glucose, is quickly glucose by Starch Hydrolysis, and internal blood sugar level rises.Right
In the glycosuria patient being main biochemical feature with lasting hyperglycemia, the fast hydrolyzing of α-amylase can increase the weight of diabetes
The degree of conditions of patients, therefore, controls diabetics body by the activity of the α-amylase in suppression intestinal
Interior blood sugar level is the major way of a kind of Diet Adjustment.Having turned out a lot of natural product can be by suppression and fall
Low intestinal and the activity of α-amylase in saliva, hinder hydrolysis and the digestion of carbohydrate in food, reach to subtract
Few human body picked-up to sugar, reduces blood sugar content in blood of human body, thus plays diabetes mellitus prevention and control
Effect.Therefore, exploitation has the natural product beverage new product of inhibitory activity to α-amylase, has huge
The market demand and application and development are worth.
Sericin in silkworm silk, as a kind of novel food protein resource, not only has edibility, and has medicine
By value, the present invention overcomes the heavy characteristic of sericin by the sericin peptide taken extract that enzymolysis obtains.
Hericium erinaceus (Bull. Ex Fr.) Pers. is the edible fungi of delicious flavour, be also a kind of rich in unsaturated fatty acid, vitamin, protein,
Aminoacid, the nutritious and healthy food of polysaccharide.In Hericium erinaceus (Bull. Ex Fr.) Pers., water soluble polysaccharide has raising immunity, defying age, fall
The physiological function such as blood fat, blood sugar lowering.
Angelica keiskei koidzumi is a kind of cold-resistant perennial Herba Oenanthes Javanicae section herbaceous plant, originates in Japan's Pacific Coast Area, rich
Containing VB rare in abundant chlorophyll, mineral, aminoacid, natural organic germanium and natural plants12。
Main composition flavone compound in angelica keiskei koidzumi has lowering blood pressure and blood fat, anti-inflammatory, prevention diabetes etc.
Effect.
Rose flower water is to extract a kind of fragrancing liquid obtained from Flos Rosae Rugosae, rich in multiple aromatic substance and multiple little
Molecular substance, has effect that fragrance is regulated the flow of vital energy, nursed one's health endocrine, moistening skin beautifying.Rose flower water is not only senior
Food flavor, is also top raw material of skin care articles.
Therefore, those skilled in the art be devoted to exploitation a kind of low in calories, there is substantially suppression α-amylase live
Property, easy to digest, improve the function of multiple health-care effect of body immunity, blood fat reducing, blood sugar lowering, moistening skin beautifying
Beverage new product formula and preparation method.
Summary of the invention
Because the drawbacks described above of prior art, it is an object of the invention to provide a kind of compounding drinks, it has
Substantially suppress alpha-amylase activity, improve body immunity, blood fat reducing, blood sugar lowering, the multiple merit of moistening skin beautifying
Can, and there is the delicate fragrance local flavor of uniqueness.
For achieving the above object, the invention provides a kind of Hericium erinaceus (Bull. Ex Fr.) Pers. having α-amylase inhibitory activity and compound beverage.
In the better embodiment of the present invention, this have the Hericium erinaceus (Bull. Ex Fr.) Pers. of α-amylase inhibitory activity compound the raw material of beverage by
The component composition of following parts by weight: Hericium erinaceus (Bull. Ex Fr.) Pers. extract 0.003～0.01 part, angelica keiskei koidzumi extract 0.05～0.5
Part, sericin peptide taken extract 0.003～0.01 part, sugar alcohol 2～8 parts, low calorie sweetener 0.000～0.003 part,
Acidic flavoring agent 0.1～0.3 part, rose flower water 1～5 parts, water 88～96 parts.
Further, above-mentioned Hericium erinaceus (Bull. Ex Fr.) Pers. extract at least includes water miscible polysaccharide, mineral and the egg in Hericium erinaceus (Bull. Ex Fr.) Pers.
White matter.
Further, above-mentioned angelica keiskei koidzumi extract at least includes the coumarin in angelica keiskei koidzumi, polysaccharide, protein and Huang
Letones.
Further, the relative molecular weight of above-mentioned sericin peptide taken extract is less than 3000Da.
Further, above-mentioned rose flower water at least includes citronellol, geraniol, nerol, Borneolum Syntheticum and acetaminol.
Further, above-mentioned sugar alcohol is selected from xylitol, maltose alcohol and Sorbitol.
Further, above-mentioned low calorie sweetener is selected from aspartame, stevioside and sucralose.
Further, above-mentioned acidic flavoring agent is selected from citric acid, malic acid and tartaric acid.
Another aspect of the present invention provides a kind of to be prepared the above-mentioned Hericium erinaceus (Bull. Ex Fr.) Pers. having α-amylase inhibitory activity and compounds beverage
Method.In a specific embodiment of the present invention, the method comprises the following steps:
1) dispensing: weigh angelica keiskei koidzumi extract, Hericium erinaceus (Bull. Ex Fr.) Pers. extract, sericin peptide taken extract, sugar alcohol, low in calories
Sweeting agent, acidic flavoring agent, rose flower water and water mix homogeneously, it is thus achieved that mixed solution one；
2) centrifugal: above-mentioned mixed solution one to be centrifuged, takes supernatant；Preferably, 2000～4000r/min
10～20min it are centrifuged under rotating speed；
3) homogenizing: above-mentioned supernatant is carried out homogenizing, it is thus achieved that mixed solution two；Preferably, 200～300Mpa
Homogenizing 5～15min under pressure；
4) degassing: above-mentioned mixed solution two is de-gassed；Preferably, under 0.1Mpa vacuum deaerate 10～
15min；
5) sterilization: by the mixed solution two ultrahigh-temperature instant sterilization after degassing；Preferably, described ultrahigh-temperature instant
Sterilization is for sterilizing 3～8 seconds at 130 DEG C～135 DEG C；
6) fill: by ultrahigh-temperature instant sterilize after mixed solution two carry out fill, it is thus achieved that described in have α-amylase
The Hericium erinaceus (Bull. Ex Fr.) Pers. of inhibitory activity compounds beverage；Preferably, at 80～85 DEG C, fill is carried out.
Further, the preparation method of above-mentioned Hericium erinaceus (Bull. Ex Fr.) Pers. extract is: the Hericium erinaceus (Bull. Ex Fr.) Pers. of drying was pulverized 40～80
Mesh sieve；The rough Hericium erinaceus (Bull. Ex Fr.) Pers. powder obtained is mixed homogeneously by 1:15～1:30 solid-liquid ratio with water, at 75 DEG C～85 DEG C
Hot water extracts 1～3 hour, centrifugal acquisition supernatant, lyophilization, it is thus achieved that Hericium erinaceus (Bull. Ex Fr.) Pers. powder；By above-mentioned hedgehog hydnum
1:10～1:30 solid-liquid ratio mix homogeneously pressed by mushroom powder and 80% ethanol, stands 1～3 hour at-18 DEG C～-23 DEG C,
Collect precipitate；Above-mentioned precipitate lyophilization is obtained above-mentioned Hericium erinaceus (Bull. Ex Fr.) Pers. extract.
Preferably, above-mentioned precipitate water redissolves, and reuses 80% Ethanol Treatment 1～2 times, the most freezing
It is dried.
Further, the preparation method of above-mentioned angelica keiskei koidzumi extract is: the fresh angelica keiskei cleaned is cleaned, chopping；
Mix homogeneously by 1:5～1:10 solid-liquid ratio with water, extract 0.5～1 hour in 50 DEG C～70 DEG C of hot water, centrifugal
Obtain supernatant one；It is evaporated above-mentioned supernatant one concentrating；Solution after concentrating is spray-dried, and obtains
Obtain angelica keiskei koidzumi powder；Above-mentioned angelica keiskei koidzumi powder and 75% ethanol are pressed 1:3～1:8 solid-liquid ratio mix homogeneously, at 50 DEG C～60
1～2 hour is stood, centrifugal acquisition supernatant two at DEG C；Above-mentioned supernatant two is carried out lyophilization and obtains above-mentioned
Angelica keiskei koidzumi extract.
Preferably, above-mentioned evaporation and concentration is carried out in film-rising evaporator, and the feeding temperature of this film-rising evaporator is
51 DEG C～53 DEG C, drop temperature is 67 DEG C～69 DEG C, and raw vapor (steam) temperature is 106 DEG C～108 DEG C, indirect steam
Temperature is 66 DEG C～68 DEG C, and cooling water inlet temperature is 14 DEG C～16 DEG C, and cooling water outlet temperature is 29 DEG C～31
℃。
Preferably, above-mentioned spray drying is the inlet temperature at 148～152 DEG C, the leaving air temp of 69～71 DEG C,
It is spray-dried under the charging rate of 498～502mL/h.
Further, the preparation method of above-mentioned sericin peptide taken extract is: the zymolyte of sericin peptide taken is crossed molecular cut off
For the film of 3K, obtain supernatant three；It is evaporated above-mentioned supernatant three concentrating, it is thus achieved that sericin Gly-His-Lys；By upper
State sericin Gly-His-Lys and 80% ethanol by 1:60～1:100 solid-liquid ratio mix homogeneously, at-18 DEG C～-22 DEG C, stand 2～3
Hour, centrifugal acquisition supernatant four, above-mentioned supernatant four is carried out lyophilization and obtains above-mentioned sericin peptide taken extract.
Preferably, above-mentioned evaporation and concentration is carried out in film-rising evaporator, and the feeding temperature of this film-rising evaporator is
43 DEG C～45 DEG C, drop temperature is 40 DEG C～42 DEG C, and raw vapor (steam) temperature is 154 DEG C～156 DEG C, indirect steam
Temperature is 41 DEG C～43 DEG C, and cooling water inlet temperature is 19 DEG C～21 DEG C, and cooling water outlet temperature is 25 DEG C～27
℃。
Further, the preparation method of above-mentioned rose flower water is, obtains described by fresh rose flower through cryogenic vacuum distillation
Rose flower water.
Preferably, the distillation of described cryogenic vacuum is steamed under under 50-70 DEG C and 0.05-0.1Mpa vacuum
Evaporate.
The present invention has the advantage that
1, the Hericium erinaceus (Bull. Ex Fr.) Pers. with α-amylase inhibitory activity that the present invention provides compounds in drinks, and sericin peptide taken has
There is stronger α-amylase inhibitory activity；In Hericium erinaceus (Bull. Ex Fr.) Pers., water soluble polysaccharide also has higher suppression to α-amylase
Activity, can form complexing agent with α-amylase and make α-amylase inactivate；Flavone compound in angelica keiskei koidzumi
The hydrolysis of starch can be delayed by the activity of suppression α-amylase.It addition, flavone compound can also lead to
Cross induced glucose transporter to suppress the internal absorption to glucose.Therefore, the compounding drinks in the present invention
Having the α-amylase inhibitory activity of collaborative enhancing, therefore, this beverage is applicable to diabetic and overweight people etc.
Special population eats.
2, the Hericium erinaceus (Bull. Ex Fr.) Pers. with α-amylase inhibitory activity that the present invention provides compounds drinks, by rose flower water
Fragrance ingredient organically blends with nutrition and the function of the water solublity functional component in Hericium erinaceus (Bull. Ex Fr.) Pers., angelica keiskei koidzumi, makes
Product has moistening skin beautifying, nourishing stomach and spleen, suppression alpha-amylase activity, the multiple health care of raising body immunity
Effect, and there is the fragrance of Flos Rosae Rugosae and Hericium erinaceus (Bull. Ex Fr.) Pers., mouthfeel that angelica keiskei koidzumi is fresh and sweet, marketing and application prospect are wide
General.
3, the sericin peptide taken extract that the present invention adds in formula designs, containing several amino acids, as serine,
Glycine, aspartic acid, alanine etc. have biological activity, such as antioxidation, prevent and treat the functions such as diabetes.This
Sericin peptide taken is applied in beverage by invention, and the trophic function that improve beverage is worth.
4, the ultrahigh-temperature instant sterilization technology that the present invention uses in process, adds the stability of beverage product,
Therefore, the design of this drink formula need not add stabilizer.This nutrient substance loss being possible not only to ensure beverage
Little, and further increase the edible safety of beverage.
Hereinafter the technique effect of design, concrete steps and generation to the present invention is described further, with fully
Understand the purpose of the present invention, feature and effect.
Detailed description of the invention
In the detailed description of the invention of the present invention, if no special instructions, the raw material used and instrument can be directly from cities
Field is bought and is obtained.
The zymolyte of the sericin peptide taken in the present invention directly can be bought from Huzhou Xintiansi Biotechnology Co. Ltd. and obtain
?.
In the present invention, " solid-liquid ratio " refers to mass volume ratio, and unit is " g/mL ".
In the detailed description of the invention of the present invention, the method that Hericium erinaceus (Bull. Ex Fr.) Pers. extract combines precipitate with ethanol by hot water extraction obtains,
This Hericium erinaceus (Bull. Ex Fr.) Pers. extract comprises water miscible polysaccharide, proteins,vitamins,minerals, unsaturated fatty acid, ammonia
Base acid etc..
In the detailed description of the invention of the present invention, angelica keiskei koidzumi extract is the side being combined evaporation and concentration by hot water extraction
Method, especially combine film-rising evaporator evaporation and concentration obtain, this angelica keiskei koidzumi extract include coumarin, polysaccharide,
Protein and Flavonoid substances etc..
In the detailed description of the invention of the present invention, sericin peptide taken extract is by after mwco membrane by the zymolyte of sericin peptide taken
The supernatant obtained, by evaporation and concentration, the evaporation and concentration acquisition sericin peptide taken especially combining film-rising evaporator is rough
Product, then obtain described sericin peptide taken extract by alcohol extraction and lyophilization.Wherein, it is thus achieved that sericin peptide taken relative
Molecular weight is less than 3000Da.
In the detailed description of the invention of the present invention, rose flower water is prepared as follows: by Flos Rosae Rugosae flower by low
The method of temperature vacuum distilling, is i.e. dried Flos Rosae Rugosae at 50-70 DEG C of temperature and 0.05-0.1Mpa vacuum, obtains
Distillate, the aqueous portion of distillate is rose flower water.This rose flower water comprises citronellol, geraniol, orange blossom
Alcohol, Borneolum Syntheticum and acetaminol etc..
Hericium erinaceus (Bull. Ex Fr.) Pers. extract, angelica keiskei koidzumi extract, the sericin peptide taken extract suppression ratio to α-amylase in the present invention
Measurement result such as following table:
Embodiment 1
A kind of Hericium erinaceus (Bull. Ex Fr.) Pers. with α-amylase inhibitory activity compounds drinks, and it is made by the steps:
1, being pulverized by the Hericium erinaceus (Bull. Ex Fr.) Pers. dried at 50 DEG C, cross 60 mesh sieves, Hericium erinaceus (Bull. Ex Fr.) Pers. powder and water press 1:20 (g/mL)
Solid-liquid ratio mix homogeneously, 80 DEG C of hot water extraction 2h, then under the conditions of 8000r/min centrifugal 15min, take centrifugal after
Supernatant lyophilization obtain Hericium erinaceus (Bull. Ex Fr.) Pers. powder.The mixing of 1:20 (g/mL) solid-liquid ratio pressed by Hericium erinaceus (Bull. Ex Fr.) Pers. powder and 80% ethanol
Uniformly, stand 2h at-20 DEG C, collect precipitate, obtained by freeze drying Hericium erinaceus (Bull. Ex Fr.) Pers. extract.
2, by clean fresh angelica keiskei chopping, mix homogeneously by 1:8 solid-liquid ratio with water, 60 DEG C of hot water extraction
45min, then (feeding temperature: 52.3 DEG C, drop temperature: 67.9 DEG C, raw steam in film-rising evaporator
Temperature: 107.8 DEG C, indirect steam temperature: 66.9 DEG C, cooling water inlet temperature: 15.3 DEG C, coolant outlet temperature
Degree: 29.3 DEG C) concentrate, the sample after concentration carries out being spray-dried (inlet temperature: 150 DEG C, go out pathogenic wind-warm
Degree: 70 DEG C, charging rate: 500mL/h) obtain angelica keiskei koidzumi powder.Solid-liquid ratio 1:5 pressed by angelica keiskei koidzumi powder and 75% ethanol
Mix homogeneously, stands 1.5h, more centrifugal 5min under the conditions of 5000r/min, takes the supernatant after being centrifuged at 55 DEG C
Lyophilization obtains angelica keiskei koidzumi extract.
3, by sericin peptide taken zymolyte, crossing molecular cut off is the film of 3K, obtains supernatant, film-rising evaporator
(feeding temperature: 44 DEG C, drop temperature: 41.5 DEG C, raw vapor (steam) temperature: 155.5 DEG C, indirect steam temperature: 41.6
DEG C, cooling water inlet temperature: 20.4 DEG C, cooling water outlet temperature: 25.7 DEG C) after concentrating sample sericin Gly-His-Lys.
1:80 solid-liquid ratio mix homogeneously pressed by sericin Gly-His-Lys and 80% ethanol, stands 2.5h, obtain supernatant, warp at-20 DEG C
Lyophilization obtains described sericin peptide taken extract.
4,0.004g Hericium erinaceus (Bull. Ex Fr.) Pers. extract, 0.3g angelica keiskei koidzumi extract, 0.004g sericin peptide taken extract, 6g are weighed
Xylitol, 0.002g stevioside, 0.3g citric acid and 5mL rose flower water mix and blend, be subsequently adding
88.39mL drinking pure water, makes each component dissolve completely, and mix homogeneously obtains mixing liquid one.
5, by above-mentioned mixed liquor one centrifugal 20min under 2000r/min rotating speed, collect supernatant, obtain mixed solution
Two.
6, above-mentioned mixed solution two is placed in homogenizing 5min under 300Mpa pressure, obtains mixed solution three.
7, above-mentioned mixed solution three is placed under 0.1Mpa vacuum degassing 15min, obtains mixed solution four.
8, above-mentioned mixed solution four is placed in ultrahigh-temperature instant sterilization 5s at 132 DEG C, obtains mixed solution five.
9, mixing liquid five obtained above is placed at 82 DEG C carries out fill.
Embodiment 2
A kind of Hericium erinaceus (Bull. Ex Fr.) Pers. with α-amylase inhibitory activity compounds drinks, and it is made by the steps:
1, being pulverized by the Hericium erinaceus (Bull. Ex Fr.) Pers. dried at 50 DEG C, cross 80 mesh sieves, then Hericium erinaceus (Bull. Ex Fr.) Pers. powder and water press 1:30 feed liquid
Ratio mix homogeneously, 85 DEG C of hot water extraction 1h, then under the conditions of 8000r/min centrifugal 15min, take centrifugal after
Supernatant lyophilization obtains Hericium erinaceus (Bull. Ex Fr.) Pers. powder.1:30 solid-liquid ratio mix homogeneously pressed by Hericium erinaceus (Bull. Ex Fr.) Pers. powder and 80% ethanol ,-23 DEG C
Lower standing 3 hours, collects precipitate, obtained by freeze drying Hericium erinaceus (Bull. Ex Fr.) Pers. extract.
2, by clean fresh angelica keiskei chopping, mix homogeneously by 1:6 solid-liquid ratio with water, 55 DEG C of hot water extraction
50min, then (feeding temperature: 52.5 DEG C, drop temperature: 67.4 DEG C, raw steam in film-rising evaporator
Temperature: 107.4 DEG C, indirect steam temperature: 66.7 DEG C, cooling water inlet temperature: 15 DEG C, cooling water outlet temperature:
29 DEG C) concentrate, the sample after concentration carries out being spray-dried (inlet temperature: 148 DEG C, leaving air temp: 69
DEG C, charging rate: 500mL/h) obtain angelica keiskei koidzumi powder.Angelica keiskei koidzumi powder and 75% ethanol press solid-liquid ratio 1:8 mixing all
Even, stand 1h, more centrifugal 5min under the conditions of 5000r/min at 60 DEG C, take the supernatant freezing after being centrifuged and do
Dry angelica keiskei koidzumi extract.
3, by sericin peptide taken zymolyte, crossing molecular cut off is the film of 3K, obtains supernatant, film-rising evaporator
(feeding temperature: 44.5 DEG C, drop temperature: 41.3 DEG C, raw vapor (steam) temperature: 155 DEG C, indirect steam temperature: 41
DEG C, cooling water inlet temperature: 20 DEG C, cooling water outlet temperature: 25.5 DEG C) after concentrating sample sericin Gly-His-Lys.
1:100 solid-liquid ratio mix homogeneously pressed by sericin Gly-His-Lys and 80% ethanol, stands 3h at-18 DEG C, obtains supernatant, cold
The dry acquisition of lyophilizing described sericin peptide taken extract.
4,0.009g Hericium erinaceus (Bull. Ex Fr.) Pers. extract, 0.38g angelica keiskei koidzumi extract, 0.01g sericin peptide taken extract, 4g are weighed
Xylitol, 0.001g stevioside, 0.1g citric acid and 1.5mL rose flower water mix and blend, be subsequently adding
The drinking pure water of 94mL, makes each component dissolve completely, and mix homogeneously obtains mixing liquid one.
5, by above-mentioned mixed liquor one centrifugal 15min under 3000r/min rotating speed, collect supernatant, obtain mixed solution
Two.
6, above-mentioned mixed solution two is placed in homogenizing 10min under 250Mpa pressure, obtains mixed solution three.
7, above-mentioned mixed solution three is placed under 0.1Mpa vacuum degassing 10min, obtains mixed solution four.
8, above-mentioned mixed solution four is placed in ultrahigh-temperature instant sterilization 3s at 135 DEG C, obtains mixed solution five.
9, mixing liquid five obtained above is placed at 83 DEG C carries out fill.
Embodiment 3
A kind of Hericium erinaceus (Bull. Ex Fr.) Pers. with α-amylase inhibitory activity compounds drinks, and it is made by the steps:
1, being pulverized by the Hericium erinaceus (Bull. Ex Fr.) Pers. dried at 50 DEG C, cross 40 mesh sieves, Hericium erinaceus (Bull. Ex Fr.) Pers. powder and water press 1:15 (g/mL)
Solid-liquid ratio mix homogeneously, 75 DEG C of hot water extraction 3h, then under the conditions of 8000r/min centrifugal 15min, take centrifugal after
Supernatant lyophilization obtain Hericium erinaceus (Bull. Ex Fr.) Pers. powder.The mixing of 1:10 (g/mL) solid-liquid ratio pressed by Hericium erinaceus (Bull. Ex Fr.) Pers. powder and 80% ethanol
Uniformly, stand 1h at-18 DEG C, collect precipitate, obtained by freeze drying Hericium erinaceus (Bull. Ex Fr.) Pers. extract.
2, by clean fresh angelica keiskei chopping, mix homogeneously by 1:5 solid-liquid ratio with water, 50 DEG C of hot water extraction
60min, then in film-rising evaporator (feeding temperature: 51 DEG C, drop temperature: 67 DEG C, raw vapor (steam) temperature:
106 DEG C, indirect steam temperature: 66 DEG C, cooling water inlet temperature: 14 DEG C, cooling water outlet temperature: 29 DEG C)
Concentrating, the sample after concentration carries out being spray-dried (inlet temperature: 152 DEG C, leaving air temp: 71 DEG C, enter
Material speed: 502mL/h) obtain angelica keiskei koidzumi powder.Solid-liquid ratio 1:3 mix homogeneously pressed by angelica keiskei koidzumi powder and 75% ethanol, and 50
Stand 2h, more centrifugal 5min under the conditions of 5000r/min at DEG C, take the supernatant lyophilization after being centrifuged and obtain bright
Day leaf extract.
3, by sericin peptide taken zymolyte, crossing molecular cut off is the film of 3K, obtains supernatant, film-rising evaporator
(feeding temperature: 43 DEG C, drop temperature: 40 DEG C, raw vapor (steam) temperature: 154 DEG C, indirect steam temperature: 41 DEG C,
Cooling water inlet temperature: 19 DEG C, cooling water outlet temperature: 25 DEG C) after concentrating sample sericin Gly-His-Lys.Sericin peptide taken
1:60 solid-liquid ratio mix homogeneously pressed by powder and 80% ethanol, stands 2h at-22 DEG C, obtains supernatant, freeze-dried
Obtain described sericin peptide taken extract.
4,0.003g Hericium erinaceus (Bull. Ex Fr.) Pers. extract, 0.05g angelica keiskei koidzumi extract, 0.003g sericin peptide taken extract are weighed,
2g maltose alcohol, 0.1g malic acid and 1mL rose flower water mix and blend, be subsequently adding 88mL and drink pure
Water, makes each component dissolve completely, and mix homogeneously obtains mixing liquid one.
5, by above-mentioned mixed liquor one centrifugal 10min under 4000r/min rotating speed, collect supernatant, obtain mixed solution
Two.
6, above-mentioned mixed solution two is placed in homogenizing 10min under 200Mpa pressure, obtains mixed solution three.
7, above-mentioned mixed solution three is placed under 0.1Mpa vacuum degassing 13min, obtains mixed solution four.
8, above-mentioned mixed solution four is placed in ultrahigh-temperature instant sterilization 8s at 130 DEG C, obtains mixed solution five.
9, mixing liquid five obtained above is placed at 80 DEG C carries out fill.
Embodiment 4
A kind of Hericium erinaceus (Bull. Ex Fr.) Pers. with α-amylase inhibitory activity compounds drinks, and it is made by the steps:
1, being pulverized by the Hericium erinaceus (Bull. Ex Fr.) Pers. dried at 50 DEG C, cross 60 mesh sieves, Hericium erinaceus (Bull. Ex Fr.) Pers. powder and water press 1:20 (g/mL)
Solid-liquid ratio mix homogeneously, 80 DEG C of hot water extraction 2h, then under the conditions of 8000r/min centrifugal 15min, take centrifugal after
Supernatant lyophilization obtain Hericium erinaceus (Bull. Ex Fr.) Pers. powder.The mixing of 1:25 (g/mL) solid-liquid ratio pressed by Hericium erinaceus (Bull. Ex Fr.) Pers. powder and 80% ethanol
Uniformly, stand 2.5h at-20 DEG C, collect precipitate, obtained by freeze drying Hericium erinaceus (Bull. Ex Fr.) Pers. extract.
2, by clean fresh angelica keiskei chopping, mix homogeneously by 1:10 solid-liquid ratio with water, 70 DEG C of hot water extraction
30min, then in film-rising evaporator (feeding temperature: 53 DEG C, drop temperature: 69 DEG C, raw vapor (steam) temperature:
108 DEG C, indirect steam temperature: 68 DEG C, cooling water inlet temperature: 16 DEG C, cooling water outlet temperature: 31 DEG C)
Concentrating, the sample after concentration carries out being spray-dried (inlet temperature: 149 DEG C, leaving air temp: 69 DEG C, enter
Material speed: 498mL/h) obtain angelica keiskei koidzumi powder.Solid-liquid ratio 1:6 mix homogeneously pressed by angelica keiskei koidzumi powder and 75% ethanol, and 55
Stand 2h, more centrifugal 5min under the conditions of 5000r/min at DEG C, take the supernatant lyophilization after being centrifuged and obtain bright
Day leaf extract.
3, by sericin peptide taken zymolyte, crossing molecular cut off is the film of 3K, obtains supernatant, film-rising evaporator
(feeding temperature: 45 DEG C, drop temperature: 42 DEG C, raw vapor (steam) temperature: 156 DEG C, indirect steam temperature: 42 DEG C,
Cooling water inlet temperature: 21 DEG C, cooling water outlet temperature: 27 DEG C) after concentrating sample sericin Gly-His-Lys.Sericin peptide taken
1:90 solid-liquid ratio mix homogeneously pressed by powder and 80% ethanol, stands 2h at-20 DEG C, obtains supernatant, freeze-dried
Obtain described sericin peptide taken extract.
4,0.01g Hericium erinaceus (Bull. Ex Fr.) Pers. extract, 0.5g angelica keiskei koidzumi extract, 0.01g sericin peptide taken extract, 8g are weighed
Sorbitol, 0.003g aspartame, 0.3g tartaric acid and 5mL rose flower water mix and blend, be subsequently adding
96mL drinking pure water, makes each component dissolve completely, and mix homogeneously obtains mixing liquid one.
5, by above-mentioned mixed liquor one centrifugal 15min under 3000r/min rotating speed, collect supernatant, obtain mixed solution
Two.
6, above-mentioned mixed solution two is placed in homogenizing 10min under 250Mpa pressure, obtains mixed solution three.
7, above-mentioned mixed solution three is placed under 0.1Mpa vacuum degassing 13min, obtains mixed solution four.
8, above-mentioned mixed solution four is placed in ultrahigh-temperature instant sterilization 3s at 135 DEG C, obtains mixed solution five.
9, mixing liquid five obtained above is placed at 85 DEG C carries out fill.
The preferred embodiment of the present invention described in detail above.Should be appreciated that the ordinary skill of this area without
Creative work just can make many modifications and variations according to the design of the present invention.Therefore, all in the art
Technical staff passes through logical analysis, reasoning, or a limited experiment the most on the basis of existing technology
Available technical scheme, all should be in the protection domain being defined in the patent claims.
Claims (10)
1. a Hericium erinaceus (Bull. Ex Fr.) Pers. with α-amylase inhibitory activity compounds beverage, it is characterised in that its raw material is by following heavy
The component composition of amount number: Hericium erinaceus (Bull. Ex Fr.) Pers. extract 0.003～0.01 part, angelica keiskei koidzumi extract 0.05～0.5 part,
Sericin peptide taken extract 0.003～0.01 part, sugar alcohol 2～8 parts, low calorie sweetener 0.000～0.003 part, acid
Taste agent 0.1～0.3 part, rose flower water 1～5 parts, water 88～96 parts.
The Hericium erinaceus (Bull. Ex Fr.) Pers. the most as claimed in claim 1 with α-amylase inhibitory activity compounds beverage, it is characterised in that
Described Hericium erinaceus (Bull. Ex Fr.) Pers. extract at least includes water miscible polysaccharide, mineral and protein in Hericium erinaceus (Bull. Ex Fr.) Pers..
The Hericium erinaceus (Bull. Ex Fr.) Pers. the most as claimed in claim 1 with α-amylase inhibitory activity compounds beverage, it is characterised in that
Described angelica keiskei koidzumi extract at least includes the coumarin in angelica keiskei koidzumi, polysaccharide, protein and Flavonoid substances.
The Hericium erinaceus (Bull. Ex Fr.) Pers. the most as claimed in claim 1 with α-amylase inhibitory activity compounds beverage, it is characterised in that
The relative molecular weight of described sericin peptide taken extract is less than 3000Da.
The Hericium erinaceus (Bull. Ex Fr.) Pers. the most as claimed in claim 1 with α-amylase inhibitory activity compounds beverage, it is characterised in that
Described rose flower water at least includes citronellol, geraniol, nerol, Borneolum Syntheticum and acetaminol.
6. prepare and there is the Hericium erinaceus (Bull. Ex Fr.) Pers. of α-amylase inhibitory activity as claimed in claim 1 compound the side of beverage for one kind
Method, it is characterised in that said method comprising the steps of:
1) dispensing: weigh angelica keiskei koidzumi extract, Hericium erinaceus (Bull. Ex Fr.) Pers. extract, sericin peptide taken extract, sugar alcohol, low in calories
Sweeting agent, acidic flavoring agent, rose flower water and water mix homogeneously, it is thus achieved that mixed solution one；
2) centrifugal: described mixed solution one to be centrifuged, takes supernatant；
3) homogenizing: described supernatant is carried out homogenizing, it is thus achieved that mixed solution two；
4) degassing: described mixed solution two is de-gassed；
5) sterilization: by the mixed solution two ultrahigh-temperature instant sterilization after degassing；
6) fill: by ultrahigh-temperature instant sterilize after mixed solution two carry out fill, it is thus achieved that described in have α-amylase
The Hericium erinaceus (Bull. Ex Fr.) Pers. of inhibitory activity compounds beverage.
7. a preparation method as claimed in claim 6, it is characterised in that the preparation side of described Hericium erinaceus (Bull. Ex Fr.) Pers. extract
Method is: the Hericium erinaceus (Bull. Ex Fr.) Pers. of drying was pulverized 40～80 mesh sieves；The rough Hericium erinaceus (Bull. Ex Fr.) Pers. powder and the water that obtain are pressed 1:15～
1:30 solid-liquid ratio mix homogeneously, extracts 1～3 hour in 75 DEG C～85 DEG C of hot water, centrifugal acquisition supernatant,
Lyophilization, it is thus achieved that Hericium erinaceus (Bull. Ex Fr.) Pers. powder；Described Hericium erinaceus (Bull. Ex Fr.) Pers. powder and 80% ethanol are pressed the mixing of 1:10～1:30 solid-liquid ratio
Uniformly, at-18 DEG C～-23 DEG C, stand 1～3 hour, collect precipitate；Described precipitate lyophilization is obtained
Obtain described Hericium erinaceus (Bull. Ex Fr.) Pers. extract.
8. a preparation method as claimed in claim 6, it is characterised in that the preparation side of described angelica keiskei koidzumi extract
Method is: the fresh angelica keiskei cleaned is cleaned, chopping；Mix homogeneously by 1:5～1:10 solid-liquid ratio with water, 50
DEG C～70 DEG C of hot water in extract 0.5～1 hour, centrifugal obtain supernatant one；Described supernatant one is evaporated
Concentrate；Solution after concentrating is spray-dried, it is thus achieved that angelica keiskei koidzumi powder；By described angelica keiskei koidzumi powder and 75% second
1:3～1:8 solid-liquid ratio mix homogeneously pressed by alcohol, stands 1～2 hour at 50 DEG C～60 DEG C, centrifugal acquisition supernatant
Liquid two；Described supernatant two is carried out lyophilization and obtains described angelica keiskei koidzumi extract.
9. a preparation method as claimed in claim 6, it is characterised in that the preparation side of described sericin peptide taken extract
Method is: the zymolyte of sericin peptide taken is crossed the film that molecular cut off is 3K, obtains supernatant three；By described supernatant
Three are evaporated concentrating, it is thus achieved that sericin Gly-His-Lys；Described sericin Gly-His-Lys and 80% ethanol are pressed 1:60～1:100 feed liquid
Ratio mix homogeneously, stands 2～3 hours at-18 DEG C～-22 DEG C, and centrifugal acquisition supernatant four, by described supernatant
Four carry out lyophilization obtains described sericin peptide taken extract.
10. a preparation method as claimed in claim 6, it is characterised in that the preparation side of described rose flower water
Method is, through cryogenic vacuum distillation, fresh rose flower is obtained described rose flower water.
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| CN106260092A (en) * | 2016-08-16 | 2017-01-04 | 安徽天乾健食品科技有限公司 | A kind of relieving restlessness removing food stagnancy bamboo perfume (or spice) mixed oil and preparation method thereof |
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Effective date of registration: 20191010 Address after: 200245 room 2005, building 2, No. 555, Dongchuan Road, Minhang District, Shanghai Patentee after: SHANGHAI JINWEIZI BIOTECHNOLOGY CO., LTD. Address before: 200240 Dongchuan Road, Shanghai, No. 800, No. Patentee before: Shanghai Jiaotong University |