CN105770806A

CN105770806A - Almond antitussive oral liquid and preparation method thereof

Info

Publication number: CN105770806A
Application number: CN201610167225.5A
Authority: CN
Inventors: 陈国华
Original assignee: FUJIAN ZHONGHE PHARMACEUTICAL Co Ltd
Current assignee: FUJIAN ZHONGHE PHARMACEUTICAL Co Ltd
Priority date: 2016-03-23
Filing date: 2016-03-23
Publication date: 2016-07-20

Abstract

The invention belongs to the field of pharmacy and particularly relates to almond antitussive oral liquid and a preparation method thereof. The almond antitussive oral liquid is made from the following medicinal materials according to parts by weight: 40-60 parts of almond, 30-45 parts of peach root, 15-40 parts of cucumber seed, 20-40 parts of grape seed powder, 25-35 parts of spinach seed powder, 10-20 parts of Chinese wolfberry leaf, 15-30 parts of Rhizoma Anemarrhenae, 20-30 parts of broccoli, 15-20 parts of dried tangerine peel, 10-15 parts of sliced ginger, 13-20 parts of Bulbus Lilii, 10-25 parts of Radix Glycyrrhizae, and 12-16 parts of Radix Polygalae. The oral liquid provided herein has the effects of expelling dryness and damp to reduce phlegm, dredging wind-heat, promoting secretion of bodily fluid, relieving cough and asthma, relaxing bowels and improving immunity, is used mainly to treat symptoms such as cough, asthma, sore throat, phlegm stagnation due to lung-heat and yellow, vicious and thick phlegm, and is safe, reliable and free of toxic and side effect.

Description

Almond cough-relieving oral liquid and preparation method thereof

Technical field

The invention belongs to pharmaceutical field, be specifically related to almond cough-relieving oral liquid and preparation method thereof.

Background technology

Cough is one of illness common in daily life, and the traditional Chinese medical science thinks that cough is because of diseases caused by external factors face, internal organs internal injury, affects in the disease having sound to have phlegm caused by lung." element portion interpretation of the cause, onset and process of an illness gas preferably save one's life collection ": " cough meaning sound without phlegm, lung qi hinder and unclear also；It is noiseless and have phlegm for coughing, spleen wet dynamic and be phlegm also.Cough meaning has phlegm and sound, and lid moves in spleen wet in lung qi due to wound, cough and for coughing also.”

Cough is a kind of protectiveness respiratory tract reflection; it is that respiratory tract is upset after (such as inflammation, foreign matter); send a kind of physiological reflex that incoming oblongata coughing centre of getting excited causes; respiratory secretions or foreign matter can be discharged; the protection cleaning of respiratory tract and unobstructed; therefore, cough is usually a kind of useful action, the most also sees healthy human body.In the ordinary course of things, to cough slightly and infrequently, as long as sputum or foreign matter being discharged, it is possible to natural remission, antitussive need not be applied.But, the dry cough violent without phlegm to those, or have phlegm and the most frequently play cough, not only increase the misery of patient, impact is had a rest and sleep, increases physical demands, even promotes the development of illness, produces other complication, the most more harm than good.So, it should suitably apply antitussive, to alleviate cough.The detrimental effect of cough, is tracheae pathology can be diffused into neighbouring bronchium, aggravates disease.It addition, the most violent cough can affect rest, go back easy consumption physical, and the destruction of alveolar wall elastic fibrous tissue can be caused, induce pulmonary emphysema.Existing drug type mostly is antibiotic, can not effectively eradicate cough, also be easily generated the resistance to the action of a drug.

Summary of the invention

It is an object of the invention to provide almond cough-relieving oral liquid and preparation method thereof, oral liquid provided by the present invention, there is eliminating dampness and eliminating phlegm, dispelling wind and heat from the body, promote the production of body fluid, relieving cough and asthma, the effect of the immunity that relaxes bowel, improves, being mainly used in the symptoms such as many, asthma, strongly fragrant, the yellow thickness of phlegm of throat tumour, lung heat phlegm of coughing, the present invention is safe and reliable, have no side effect.

For achieving the above object, the present invention adopts the following technical scheme that

Almond cough-relieving oral liquid, bulk drug composition includes by weight: almond 40-60 part, peach root 30-45 part, cucumber seed 15-40 part, grape pip powder 20-40 part, spinach seed powder 25-35 part, folium lycii 10-20 part, wind-weed 15-30 part, broccoli 20-30 part, dried orange peel 15-20 part, ginger splices 10-15 part, lily 13-20 part, Radix Glycyrrhizae 10-25 part, polygala root 12-16 part.

Preferably, bulk drug composition includes by weight: 50 parts of almond, peach root 40 parts, cucumber seed 30 parts, 30 parts of grape pip powder, 30 parts of spinach seed powder, folium lycii 15 parts, the wind-weed 23 parts, broccoli 25 parts, dried orange peel 17 parts, ginger splices 13 parts, lily 17 parts, 20 parts of Radix Glycyrrhizae, polygala root 14 parts.

Almond cough-relieving oral liquor, described method includes the following:

(1) almond is deoiled take slag, after removing the water soaking 2h that the almond after oil adds 6 times of weight, with steam distillation, collect almond juice distillate, standby；

(2) extracting liquorice decocts three times, add the soak by water 2h of 8 times of weight for the first time, filter and obtain liquid, second time adds the soak by water 2h of 4 times of weight, filter and obtain liquid, third time adds the soak by water 2h of 4 times of weight, filter and obtain liquid, merge 3 liquids at 80-85 DEG C, be concentrated into the thick paste that water content is 10-30%, thick paste is added 1-3 times of weight water heating for dissolving again, filter, collect filtrate, add the ethanol of 85%, making alcohol content is 65%, stand 12 hours, centrifuging and taking supernatant, in sediment add 3 times 65% ethanol washing 2 this, the most all stand 12 hours, centrifuging and taking supernatant, merge No. 3 extracts, stand 1-2h；Reclaim extract ethanol, be concentrated into density 1.20-1.30, add purified water and ethanol makes alcohol content reach 20-25%, add liquor ammoniae fortis regulation pH7.5-8.5, stand 12h, filter and be liquid extract of liquorice, standby；

(3) take dried orange peel to pulverize, make solvent with 6 times of weight 60% alcohol, impregnate 24h, with the speed diacolation of per kilogram medicinal material 1-3mL per minute, collect just filtrate, stand-by；Continuing diacolation colourless to percolate, will be concentrated into density 1.25-1.30 at percolate again 50-55 DEG C, first filtrate and concentrate are mixed, it is 38-48% that the ethanol of addition 60% is diluted to alcohol content；Stand 12h, filter, it is thus achieved that Pericarpium Citri Reticulatae fluidextract, standby；

(4) take polygala root to pulverize, with 6 times of weight 60% ethanol as solvent, impregnate 24h, with the speed diacolation of per kilogram medicinal material 1-3mL per minute, collect just filtrate, stand-by；Continuing diacolation colourless to percolate, will be concentrated into density 1.25-1.30 at percolate again 50-55 DEG C, first filtrate and concentrate are mixed, it is 38-48% that the ethanol of addition 60% is diluted to alcohol content；Stand 12h, filter, it is thus achieved that as far as liquid extract, standby；

(5) take fresh broccoli clean after, dry, be cut into small pieces together with peach root, cucumber seed, folium lycii, the wind-weed, ginger splices, lily, add 2-3 times of volume water, at 95-105 DEG C decoct 60min, filter, it is thus achieved that filtrate and the dregs of a decoction, standby；

(6) grape pip powder is mixed with spinach seed powder it is contained in gauze bag, join in step (5) dregs of a decoction, add the water of 2-3 times of volume, at 95-105 DEG C, decoct 60min, decocts 2 times, by filtrate mixing；

(7) by almond juice distillate, liquid extract of liquorice, Pericarpium Citri Reticulatae fluidextract, mix with the filtrate in step (5), (6) as far as liquid extract, after filtering with 10-25 micron titanium rod, it is concentrated into 1/2 volume, add honey, honey and volume ratio 1:30-40 of concentrate, stir, be almond cough-relieving oral liquid.

Grape pip powder and spinach seed powder are to take grape pip and spinach seed respectively to obtain through conventional steps drying and crushing.

Almond is rich in nutritional labelings such as protein, fat, carbohydrate, carrotene, B family vitamin, vitamin C, citrin and calcium, phosphorus, iron.Wherein the content of carrotene is only second to mango in fruit, and almond is referred to as anticancer fruit by people.Almond contains abundant fat oil, has the effect reducing cholesterol, and therefore, almond has good effect to preventing and treating disease of cardiovascular system；Traditional Chinese medicine theory is thought, almond have promote the production of body fluid to quench thirst, effect of moistening lung Dingchuan, be usually used in the dryness of the lung and the health care of patient and the treatment such as breath with cough.Dessert almond, as food, can make the substitute of almond benevolence.

Peach root, clearing heat and promoting diuresis, promoting blood circulation and stopping pain；Subduing inflammation.Main jaundice；Spit blood；Bleeding from five sense organs or subcutaneous tissue；Through closing；Carbuncle swells；Hemorrhoid；Arthralgia due to wind-dampness；Fall and beat internal lesion caused by overexertion pain；Pain in the back；Eruptive disease is suffered from abdominal pain.

Being mainly composed of of cucumber seed: multiple free amino acid (wherein hydroxymalonic acid has fat-reducing and effect of prevention coronary heart disease at human body) and the glucoside such as vitamin, wood sugar, fructose and rutin, Isoquercitrin, arginic glycoside, carrotene and other is to the useful mineral matter of human body, thiamine, riboflavin.

Grape pip is containing abundant OPC, and the latter is described as " natural skin care item ", energy anti-oxidant, antiallergy, delay skin aging, has suppression platelet aggregation and the effect of atherogenesis concurrently.

Spinach seed powder is often taken and can be prevented PUD D.Primary efficacy is supported lung, treatment pulmonary tuberculosis, asthma, is coughed, clears up PUD D etc., better with taking with cucumber seed powder.

Folium lycii effect: liver-kidney tonifying, promotes the production of body fluid to quench thirst, and dispels rheumatism, promoting blood circulation and removing blood stasis.Control deficient fever, polydipsia, hot eyes dusk pain, yctalopia of hiding from view, under uterine bleeding band, hot carbuncle toxin.

The dry root-like stock of the wind-weed is famous Chinese medicine, property bitter cold, have nourishing Yin and falling fire, moisturize laxation, profit stool and urine effect.Belong to gunpowder under heat-clearing, cure mainly: warm heat disease, high hot polydipsia, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, stranguria with turbid discharge of quenching one's thirst.

Lily has Yin nourishing and lung moistening, effect of clearing away the heart fire and tranquillizing.Being usually used in deficiency of Yin cough caused by dryness, labor is coughed hemoptysis, and dysphoria is palpitated with fear, and insomnia and dreamful sleep is absent-minded.

Composition contained by ginger can effectively treat the diseases such as gastrointestinal disease, cold, rheumatalgia and n and V, and strengthens body immunity.So people cook the interest of ginger is the most alone, and it is healthy more to focus on them.

Radix Glycyrrhizae is invigorated the spleen and benefited qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.

Polygala root (formal name used at school: Polygala tenuifolia Willd), have another name called around, etc..Produce northeast, North China, northwest and Central China and Sichuan；Perennial herb, main root is sturdy, bast meat.Having intelligence development of calming the nerves, the function eliminated the phlegm, subside a swelling, the insomnia and dreamful sleep caused for breakdown of the normal physiological coordination between the heart and the kidney, forgetful palpitation with fear, wandering, expectoration is not well, sore swollen toxin, mastosis.

It is an advantage of the current invention that: the present invention each medicine compatibility, cure mainly cough and asthma, the symptom going eliminating dampness and eliminating phlegm, dispelling wind and heat from the body etc. to be caused by cough, reach the expection purpose of effect and the cure diseases treated both principal and secondary aspect of disease, the formulation of medicine the most of the present invention is oral liquid, is beneficial to absorb, easy to use, safe, have no side effect, cure rate is the highest, noresidue, raw material is cheap simultaneously, and simple process is feasible, is the traditional Chinese medicine oral liquid of a kind of good treatment cough and asthma.

Detailed description of the invention

Almond cough-relieving oral liquid, bulk drug composition includes almond 40-60 part, peach root 30-45 part, cucumber seed 15-40 part, grape pip powder 20-40 part, spinach seed powder 25-35 part, folium lycii 10-20 part, wind-weed 15-30 part, broccoli 20-30 part, dried orange peel 15-20 part, ginger splices 10-15 part, lily 13-20 part, Radix Glycyrrhizae 10-25 part, polygala root 12-16 part by weight.

Almond cough-relieving oral liquor, described method includes the following:

Embodiment 1

Almond cough-relieving oral liquid, bulk drug composition includes by weight: 50 parts of almond, peach root 40 parts, cucumber seed 30 parts, 30 parts of grape pip powder, 30 parts of spinach seed powder, folium lycii 15 parts, the wind-weed 23 parts, broccoli 25 parts, dried orange peel 17 parts, ginger splices 13 parts, lily 17 parts, 20 parts of Radix Glycyrrhizae, polygala root 14 parts.

Almond cough-relieving oral liquor, described method includes the following:

(2) extracting liquorice decocts three times, add the soak by water 2h of 8 times of weight for the first time, filter and obtain liquid, second time adds the soak by water 2h of 4 times of weight, filter and obtain liquid, third time adds the soak by water 2h of 4 times of weight, filter and obtain liquid, merge 3 liquids at 85 DEG C, be concentrated into the thick paste that water content is 30%, thick paste is added 1 times of weight water heating for dissolving again, filter, collect filtrate, add the ethanol of 85%, making alcohol content is 65%, stand 12 hours, centrifuging and taking supernatant, in sediment add 3 times 65% ethanol washing 2 this, the most all stand 12 hours, centrifuging and taking supernatant, merge No. 3 extracts, stand 2h；Reclaim extract ethanol, be concentrated into density 1.25, add purified water and ethanol makes alcohol content reach 25%, add liquor ammoniae fortis regulation pH8.5, stand 12h, filter and be liquid extract of liquorice, standby；

(3) take dried orange peel to pulverize, make solvent with 6 times of weight 60% alcohol, impregnate 24h, with the speed diacolation of per kilogram medicinal material 3mL per minute, collect just filtrate, stand-by；Continuing diacolation colourless to percolate, will be concentrated into density 1.27 at percolate again 55 DEG C, first filtrate and concentrate are mixed, it is 48% that the ethanol of addition 60% is diluted to alcohol content；Stand 12h, filter, it is thus achieved that Pericarpium Citri Reticulatae fluidextract, standby；

(4) take polygala root to pulverize, with 6 times of weight 60% ethanol as solvent, impregnate 24h, with the speed diacolation of per kilogram medicinal material 3mL per minute, collect just filtrate, stand-by；Continuing diacolation colourless to percolate, will be concentrated into density 1.27 at percolate again 55 DEG C, first filtrate and concentrate are mixed, it is 48% that the ethanol of addition 60% is diluted to alcohol content；Stand 12h, filter, it is thus achieved that as far as liquid extract, standby；

(5) take fresh broccoli clean after, dry, be cut into small pieces together with peach root, cucumber seed, folium lycii, the wind-weed, ginger splices, lily, add 3 times of volumes water, at 100 DEG C decoct 60min, filter, it is thus achieved that filtrate and the dregs of a decoction, standby；

(6) grape pip powder is mixed with spinach seed powder it is contained in gauze bag, join in step (5) dregs of a decoction, add the water of 3 times of volumes, at 100 DEG C, decoct 60min, decocts 2 times, by filtrate mixing；

(7) by almond juice distillate, liquid extract of liquorice, Pericarpium Citri Reticulatae fluidextract, mix with the filtrate in step (5), (6) as far as liquid extract, after filtering with 25 microns of titanium rods, it is concentrated into 1/2 volume, add honey, honey and volume ratio 1:40 of concentrate, stir, be almond cough-relieving oral liquid.

Embodiment 2

Almond cough-relieving oral liquid, bulk drug composition includes by weight: 40 parts of almond, peach root 30 parts, cucumber seed 15 parts, 20 parts of grape pip powder, 25 parts of spinach seed powder, folium lycii 10 parts, the wind-weed 15 parts, broccoli 20 parts, dried orange peel 15 parts, ginger splices 10 parts, lily 13 parts, 10 parts of Radix Glycyrrhizae, polygala root 12 parts.

Almond cough-relieving oral medicine liquid preparation method, described method includes the following:

(2) extracting liquorice decocts three times, add the soak by water 2h of 8 times of weight for the first time, filter and obtain liquid, second time adds the soak by water 2h of 4 times of weight, filter and obtain liquid, third time adds the soak by water 2h of 4 times of weight, filter and obtain liquid, merge 3 liquids at 80 DEG C, be concentrated into the thick paste that water content is 10%, thick paste is added 3 times of weight water heating for dissolving again, filter, collect filtrate, add the ethanol of 85%, making alcohol content is 65%, stand 12 hours, centrifuging and taking supernatant, in sediment add 3 times 65% ethanol washing 2 this, the most all stand 12 hours, centrifuging and taking supernatant, merge No. 3 extracts, stand 1h；Reclaim extract ethanol, be concentrated into density 1.20, add purified water and ethanol makes alcohol content reach 20%, add liquor ammoniae fortis regulation pH7.5, stand 12h, filter and be liquid extract of liquorice, standby；

(3) take dried orange peel to pulverize, make solvent with 6 times of weight 60% alcohol, impregnate 24h, with the speed diacolation of per kilogram medicinal material 1mL per minute, collect just filtrate, stand-by；Continuing diacolation colourless to percolate, will be concentrated into density 1.25 at percolate again 50 DEG C, first filtrate and concentrate are mixed, it is 38% that the ethanol of addition 60% is diluted to alcohol content；Stand 12h, filter, it is thus achieved that Pericarpium Citri Reticulatae fluidextract, standby；

(4) take polygala root to pulverize, with 6 times of weight 60% ethanol as solvent, impregnate 24h, with the speed diacolation of per kilogram medicinal material 1mL per minute, collect just filtrate, stand-by；Continuing diacolation colourless to percolate, will be concentrated into density 1.25 at percolate again 50 DEG C, first filtrate and concentrate are mixed, it is 38% that the ethanol of addition 60% is diluted to alcohol content；Stand 12h, filter, it is thus achieved that as far as liquid extract, standby；

(5) take fresh broccoli clean after, dry, be cut into small pieces together with peach root, cucumber seed, folium lycii, the wind-weed, ginger splices, lily, add 2 times of volumes water, at 95 DEG C decoct 30min, filter, it is thus achieved that filtrate and the dregs of a decoction, standby；

(6) grape pip powder is mixed with spinach seed powder it is contained in gauze bag, join in step (5) dregs of a decoction, add the water of 2 times of volumes, at 95 DEG C, decoct 60min, decocts 2 times, by filtrate mixing；

(7) by almond juice distillate, liquid extract of liquorice, Pericarpium Citri Reticulatae fluidextract, mix with the filtrate in step (5), (6) as far as liquid extract, after filtering with 10 microns of titanium rods, it is concentrated into 1/2 volume, add honey, honey and volume ratio 1:30 of concentrate, stir, be almond cough-relieving oral liquid.

Embodiment 3

Almond cough-relieving oral liquid, bulk drug composition includes by weight: 60 parts of almond, peach root 45 parts, cucumber seed 40 parts, 40 parts of grape pip powder, 35 parts of spinach seed powder, folium lycii 20 parts, the wind-weed 30 parts, broccoli 30 parts, dried orange peel 20 parts, ginger splices-15 parts, lily 20 parts, 25 parts of Radix Glycyrrhizae, polygala root 16 parts.

(2) extracting liquorice decocts three times, add the soak by water 2h of 8 times of weight for the first time, filter and obtain liquid, second time adds the soak by water 2h of 4 times of weight, filter and obtain liquid, third time adds the soak by water 2h of 4 times of weight, filter and obtain liquid, merge 3 liquids at 82 DEG C, be concentrated into the thick paste that water content is 20%, thick paste is added 2 times of weight water heating for dissolving again, filter, collect filtrate, add the ethanol of 85%, making alcohol content is 65%, stand 12 hours, centrifuging and taking supernatant, in sediment add 3 times 65% ethanol washing 2 this, the most all stand 12 hours, centrifuging and taking supernatant, merge No. 3 extracts, stand 2h；Reclaim extract ethanol, be concentrated into density 1.30, add purified water and ethanol makes alcohol content reach 25%, add liquor ammoniae fortis regulation pH8.5, stand 12h, filter and be liquid extract of liquorice, standby；

(3) take dried orange peel to pulverize, make solvent with 6 times of weight 60% alcohol, impregnate 24h, with the speed diacolation of per kilogram medicinal material 2mL per minute, collect just filtrate, stand-by；Continuing diacolation colourless to percolate, will be concentrated into density 1.30 at percolate again 52 DEG C, first filtrate and concentrate are mixed, it is 43% that the ethanol of addition 60% is diluted to alcohol content；Stand 12h, filter, it is thus achieved that Pericarpium Citri Reticulatae fluidextract, standby；

(4) take polygala root to pulverize, with 6 times of weight 60% ethanol as solvent, impregnate 24h, with the speed diacolation of per kilogram medicinal material 2mL per minute, collect just filtrate, stand-by；Continuing diacolation colourless to percolate, will be concentrated into density 1.30 at percolate again 53 DEG C, first filtrate and concentrate are mixed, it is 43% that the ethanol of addition 60% is diluted to alcohol content；Stand 12h, filter, it is thus achieved that as far as liquid extract, standby；

(5) take fresh broccoli clean after, dry, be cut into small pieces together with peach root, cucumber seed, folium lycii, the wind-weed, ginger splices, lily, add 3 times of volumes water, at 105 DEG C decoct 45min, filter, it is thus achieved that filtrate and the dregs of a decoction, standby；

(6) grape pip powder is mixed with spinach seed powder it is contained in gauze bag, join in step (5) dregs of a decoction, add the water of 3 times of volumes, at 105 DEG C, decoct 45min, decocts 2 times, by filtrate mixing；

(7) by almond juice distillate, liquid extract of liquorice, Pericarpium Citri Reticulatae fluidextract, mix with the filtrate in step (5), (6) as far as liquid extract, after filtering with 15 microns of titanium rods, it is concentrated into 1/2 volume, add honey, honey and volume ratio 1:35 of concentrate, stir, be almond cough-relieving oral liquid.

Clinical data

Physical data: patient 250 examples, the maleest 132 examples, female 118 example, age 6～53 years old, morbidity 2～4d.

Diagnostic criteria: formulate pertinent regulations in " flu diagnostic point prevention effect criterion (draft) " in (on May 24th, 1978) with reference to the anti-Collaboration on Scientific Research forum that cures cold in the whole nation.Flu means the acute upper respiratory infection that virus causes, clinical manifestation, and based on local symptom, constitutional symptom can have or inconspicuous, 1. local symptom: runny nose, sneeze, and nasal obstruction is coughed sometimes, pharyngalgia, and trachyphonia is shed tears；2. constitutional symptom: general malaise, chilly generates heat, headache and dizziness, four limbs aching pain in waist and back；3. blood picture: leucocyte mostly is normal or reduces.

Methods for the treatment of: the traditional Chinese medicine oral liquid of oral embodiment 1 preparation, every day twice sooner or later, each 10ml, one after each meal.Curative effect is observed after three days.

Criterion of therapeutical effect: with reference to " practical combination of Chinese tradiational and Western medicine diagnoses and treatment " i.e.: with the curer that falls ill within 24h as objects of statistics when judging curative effect；Effective: to take in 24h, constitutional symptom and local cardinal symptom are as heating, runny nose etc. disappear or substantially disappear；Effective: whole body and the local cardinal symptom in 24～48h of taking medicine such as disappearances such as heating, runny noses or disappears substantially, high hot patient (more than 39 DEG C) temperature decline more than 2 DEG C in 24h, and no longer rise person；Invalid: not meet above standard person, it is invalid to be.

Treatment results: 250 In example patient, effective: 224 examples, effectively: 25 examples, invalid 1 example, total effective rate 99.99%.

The foregoing is only presently preferred embodiments of the present invention, all impartial changes done according to scope of the present invention patent and modification, all should belong to the covering scope of the present invention.

Claims

1. almond cough-relieving oral liquid, it is characterised in that: bulk drug composition includes by weight: almond 40-60 part, peach root 30-45 part, cucumber seed 15-40 part, grape pip powder 20-40 part, spinach seed powder 25-35 part, folium lycii 10-20 part, wind-weed 15-30 part, broccoli 20-30 part, dried orange peel 15-20 part, ginger splices 10-15 part, lily 13-20 part, Radix Glycyrrhizae 10-25 part, polygala root 12-16 part.

Almond cough-relieving oral liquid the most according to claim 1, it is characterised in that: bulk drug composition includes by weight: 50 parts of almond, peach root 40 parts, cucumber seed 30 parts, 30 parts of grape pip powder, 30 parts of spinach seed powder, folium lycii 15 parts, the wind-weed 23 parts, broccoli 25 parts, dried orange peel 17 parts, ginger splices 13 parts, lily 17 parts, 20 parts of Radix Glycyrrhizae, polygala root 14 parts.

3. the preparation method of an almond cough-relieving oral liquid as claimed in claim 1, it is characterised in that: described method includes the following: