CN105770727A - Preparation technology of poria cocos and glossy ganoderma health-care compound preparation - Google Patents
Preparation technology of poria cocos and glossy ganoderma health-care compound preparation Download PDFInfo
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- CN105770727A CN105770727A CN201610120065.9A CN201610120065A CN105770727A CN 105770727 A CN105770727 A CN 105770727A CN 201610120065 A CN201610120065 A CN 201610120065A CN 105770727 A CN105770727 A CN 105770727A
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- poria
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- rhizoma curcumae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Alternative & Traditional Medicine (AREA)
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- Biochemistry (AREA)
- Materials Engineering (AREA)
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- Medicines Containing Plant Substances (AREA)
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Abstract
The invention discloses a preparation technology of a poria cocos and glossy ganoderma health-care compound preparation.The preparation technology comprises the following preparation steps of raw material selecting, raw material refining, raw material extracting and raw material extract mixing.According to the preparation technology of the poria cocos and glossy ganoderma health-care compound preparation, rich biological resources of the Dabie Mountain area are fully utilized, development and research of nutritious foods taking poria cocos as the main raw material are carried out, a traditional method for treating a malignant tumor is changed, and the immune function of human bodies is enhanced by adjusting immune factors in the human bodies, so that the purpose of assisting in inhibiting a cancer and treating the cancer is achieved; meanwhile, a latest basic research result is utilized, the technology of conducting alcohol extraction and then conducting decocting with water is adopted, recognized polysaccharide ingredients in medicinal materials of poria cocos and glossy ganoderma are extracted, terpenoid ingredients in poria cocos and glossy ganoderma are extracted, and the effect of the nutritious foods is enhanced.
Description
Technical field
The present invention relates to health product technology field, be specially the preparation technology of the strong compound preparation of a kind of Poria rock.
Background technology
Progress along with the change of human habitat, living standard and life style and medical science, spectrum of disease there occurs significant change, general infectious disease is controlled gradually, and malignant tumor then becomes one of principal disease of day by day common and serious threat human life and quality of life.Report according to World Health Organization (WHO) (WHO), tumor has become the important public hygiene problem of 21 century facing mankind].At present, malignant tumor has become one of most serious disease threatening human health.World Health Organization (WHO) estimates according to regions of the world cancer morbidity, mortality rate and world population data, and malignant tumor person is died from the whole world every year in recent years is 6,900,000 people, and new cases are 8,700,000, and existing ill example is 37,100,000.Malignant tumor causes the loss of a large amount of power, a large amount of consumption of social resources.Malignant tumor returns patient and family brings immeasurable emotional distress.Therefore, malignant tumor has become the significant problem of whole mankind's common concern.The present invention adopts Poria, Ganoderma and the unification of Rhizoma Curcumae Longae three medicine to make compound preparation will pass through to regulate the immune factor in human body, and the immunologic function of enhancing human body, to reach to press down the purpose that cancer is for cancer.
Summary of the invention
It is an object of the invention to provide the preparation technology of the strong compound preparation of a kind of Poria rock, with the problem solving to propose in above-mentioned background technology.
For achieving the above object, the present invention provides following technical scheme: the preparation technology of the strong compound preparation of a kind of Poria rock, including being made by step:
S1: raw material is chosen, chooses condition excellent, time Poria up to standard, Ganoderma and Rhizoma Curcumae Longae, and the surface of Poria, Ganoderma and Rhizoma Curcumae Longae is carried out scrubbing, then dries under normal temperature environment；
S2: raw material refines, is separately added in lapping device is ground into powder the Poria after drying, Ganoderma and Rhizoma Curcumae Longae, and the powder fining degree of Poria, Ganoderma and Rhizoma Curcumae Longae is 100-200 order；
S3: raw material extracts；
The first step: the triterpenoid compound of Poria and Ganoderma extracts, the powder of Poria and Ganoderma is separately added in corresponding reactor, then in reactor, add alcoholic solution, and stir 30-50 minute, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize rustless steel multiple-effect vacuum concentration tower to obtain triterpenoid compound after mixed solution is concentrated；
Second step: the Polyose extraction of Poria and Ganoderma, pure water is added by the reactor of residual Poria and Ganoderma medicinal residues, and stir 40-60 minute, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize steam spray drying tower that mixed solution is dried and obtain polysaccharide；
3rd step: the curcumin of Rhizoma Curcumae Longae extracts, the powder of Rhizoma Curcumae Longae is added in reactor, then in reactor, add alcoholic solution, and stir 20-40 minute, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize rustless steel multiple-effect vacuum concentration tower to obtain curcumin after mixed solution is concentrated；
S4: raw extract mixes, the triterpenoid compound after Poria, Ganoderma and Rhizoma Curcumae Longae being extracted, polysaccharide and curcumin add in stirring container, are sufficiently stirred for, until mix homogeneously, then according to etc. weight carry out subpackage and obtain the strong compound preparation of Poria rock.
Preferably, the alcoholic solution and the pure water that add in the first step, second step and the 3rd step in described S3 are no less than twice.
Compared with prior art, the invention has the beneficial effects as follows: the present invention takes full advantage of the abundant living resources of Da Bie Mountain area, carry out the nutraceutical developmental research being primary raw material with Poria, the method of traditional treatment malignant tumor will be changed, by regulating the immune factor in human body, strengthen the immunologic function of human body, press down, to reach to assist, the purpose that cancer is for cancer.Utilize up-to-date Basic Research Results simultaneously, take alcohol extraction decocting technique again, not only extract the polysaccharide component generally acknowledged in Poria, Ganoderma medical material, also extract ter penoids therein, strengthen the effect of nutraceutical.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, technical scheme is clearly and completely described, it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, the every other embodiment that those of ordinary skill in the art obtain under not making creative work premise, broadly fall into the scope of protection of the invention.
Embodiment one
A kind of preparation technology of the strong compound preparation of Poria rock, including being made by step:
S1: raw material is chosen, chooses condition excellent, time Poria up to standard, Ganoderma and Rhizoma Curcumae Longae, and the surface of Poria, Ganoderma and Rhizoma Curcumae Longae is carried out scrubbing, then dries under normal temperature environment；
S2: raw material refines, is separately added in lapping device is ground into powder the Poria after drying, Ganoderma and Rhizoma Curcumae Longae, and the powder fining degree of Poria, Ganoderma and Rhizoma Curcumae Longae is 150 orders；
S3: raw material extracts；
The first step: the triterpenoid compound of Poria and Ganoderma extracts, the powder of Poria and Ganoderma is separately added in corresponding reactor, then in reactor, add alcoholic solution, and stir 35 minutes, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize rustless steel multiple-effect vacuum concentration tower to obtain triterpenoid compound after mixed solution is concentrated；
Second step: the Polyose extraction of Poria and Ganoderma, pure water is added by the reactor of residual Poria and Ganoderma medicinal residues, and stir 45 minutes, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize steam spray drying tower that mixed solution is dried and obtain polysaccharide；
3rd step: the curcumin of Rhizoma Curcumae Longae extracts, the powder of Rhizoma Curcumae Longae is added in reactor, then in reactor, add alcoholic solution, and stir 30 minutes, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize rustless steel multiple-effect vacuum concentration tower to obtain curcumin after mixed solution is concentrated；
The alcoholic solution and the pure water that add in the first step, second step and the 3rd step in described S3 are no less than twice；
S4: raw extract mixes, the triterpenoid compound after Poria, Ganoderma and Rhizoma Curcumae Longae being extracted, polysaccharide and curcumin add in stirring container, are sufficiently stirred for, until mix homogeneously, then according to etc. weight carry out subpackage and obtain the strong compound preparation of Poria rock.
Embodiment two
A kind of preparation technology of the strong compound preparation of Poria rock, including being made by step:
S1: raw material is chosen, chooses condition excellent, time Poria up to standard, Ganoderma and Rhizoma Curcumae Longae, and the surface of Poria, Ganoderma and Rhizoma Curcumae Longae is carried out scrubbing, then dries under normal temperature environment；
S2: raw material refines, is separately added in lapping device is ground into powder the Poria after drying, Ganoderma and Rhizoma Curcumae Longae, and the powder fining degree of Poria, Ganoderma and Rhizoma Curcumae Longae is 125 orders；
S3: raw material extracts；
The first step: the triterpenoid compound of Poria and Ganoderma extracts, the powder of Poria and Ganoderma is separately added in corresponding reactor, then in reactor, add alcoholic solution, and stir 40 minutes, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize rustless steel multiple-effect vacuum concentration tower to obtain triterpenoid compound after mixed solution is concentrated；
Second step: the Polyose extraction of Poria and Ganoderma, pure water is added by the reactor of residual Poria and Ganoderma medicinal residues, and stir 50 minutes, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize steam spray drying tower that mixed solution is dried and obtain polysaccharide；
3rd step: the curcumin of Rhizoma Curcumae Longae extracts, the powder of Rhizoma Curcumae Longae is added in reactor, then in reactor, add alcoholic solution, and stir 35 minutes, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize rustless steel multiple-effect vacuum concentration tower to obtain curcumin after mixed solution is concentrated；
The alcoholic solution and the pure water that add in the first step, second step and the 3rd step in described S3 are no less than twice；
S4: raw extract mixes, the triterpenoid compound after Poria, Ganoderma and Rhizoma Curcumae Longae being extracted, polysaccharide and curcumin add in stirring container, are sufficiently stirred for, until mix homogeneously, then according to etc. weight carry out subpackage and obtain the strong compound preparation of Poria rock.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, being appreciated that and these embodiments can be carried out multiple change, amendment, replacement and modification without departing from the principles and spirit of the present invention, the scope of the present invention be defined by the appended.
Claims (2)
1. the preparation technology of the strong compound preparation of Poria rock, it is characterised in that: include being made by step:
S1: raw material is chosen, chooses condition excellent, time Poria up to standard, Ganoderma and Rhizoma Curcumae Longae, and the surface of Poria, Ganoderma and Rhizoma Curcumae Longae is carried out scrubbing, then dries under normal temperature environment；
S2: raw material refines, is separately added in lapping device is ground into powder the Poria after drying, Ganoderma and Rhizoma Curcumae Longae, and the powder fining degree of Poria, Ganoderma and Rhizoma Curcumae Longae is 100-200 order；
S3: raw material extracts；
The first step: the triterpenoid compound of Poria and Ganoderma extracts, the powder of Poria and Ganoderma is separately added in corresponding reactor, then in reactor, add alcoholic solution, and stir 30-50 minute, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize rustless steel multiple-effect vacuum concentration tower to obtain triterpenoid compound after mixed solution is concentrated；
Second step: the Polyose extraction of Poria and Ganoderma, pure water is added by the reactor of residual Poria and Ganoderma medicinal residues, and stir 40-60 minute, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize steam spray drying tower that mixed solution is dried and obtain polysaccharide；
3rd step: the curcumin of Rhizoma Curcumae Longae extracts, the powder of Rhizoma Curcumae Longae is added in reactor, then in reactor, add alcoholic solution, and stir 20-40 minute, then utilize plate and frame ultrafilter to leach the mixed solution in reactor, then utilize rustless steel multiple-effect vacuum concentration tower to obtain curcumin after mixed solution is concentrated；
S4: raw extract mixes, the triterpenoid compound after Poria, Ganoderma and Rhizoma Curcumae Longae being extracted, polysaccharide and curcumin add in stirring container, are sufficiently stirred for, until mix homogeneously, then according to etc. weight carry out subpackage and obtain the strong compound preparation of Poria rock.
2. the preparation technology of the strong compound preparation of a kind of Poria rock according to claim 1, it is characterised in that: the alcoholic solution and the pure water that add in the first step, second step and the 3rd step in described S3 are no less than twice.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610120065.9A CN105770727A (en) | 2016-03-03 | 2016-03-03 | Preparation technology of poria cocos and glossy ganoderma health-care compound preparation |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610120065.9A CN105770727A (en) | 2016-03-03 | 2016-03-03 | Preparation technology of poria cocos and glossy ganoderma health-care compound preparation |
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| CN105770727A true CN105770727A (en) | 2016-07-20 |
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| CN201610120065.9A Pending CN105770727A (en) | 2016-03-03 | 2016-03-03 | Preparation technology of poria cocos and glossy ganoderma health-care compound preparation |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102145024A (en) * | 2010-02-04 | 2011-08-10 | 深圳市汇康生物科技有限公司 | Fungal composition with effect of enhancing immunity and preparation method thereof |
| CN103110889A (en) * | 2013-02-01 | 2013-05-22 | 北京东方红航天生物技术股份有限公司 | Traditional Chinese medicine for increasing immunity and preparation method thereof |
-
2016
- 2016-03-03 CN CN201610120065.9A patent/CN105770727A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102145024A (en) * | 2010-02-04 | 2011-08-10 | 深圳市汇康生物科技有限公司 | Fungal composition with effect of enhancing immunity and preparation method thereof |
| CN103110889A (en) * | 2013-02-01 | 2013-05-22 | 北京东方红航天生物技术股份有限公司 | Traditional Chinese medicine for increasing immunity and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 孙亚红: "《灵芝从神奇到科学种植》", 31 December 2015, 中国农业大学出版社 * |
| 彭成等: "《中药药理学》", 31 December 2014, 中国医药科技出版社 * |
| 无锡轻工业学院等编: "《食品工厂机械与设备》", 28 February 1981, 轻工业出版社 * |
| 陈琼等: "《中药制剂技术 第2版》", 30 November 2014, 中国农业大学出版社 * |
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