CN105770296B - A kind of Traditional Chinese medicine for tranquilization sachet and its preparation method and application - Google Patents

A kind of Traditional Chinese medicine for tranquilization sachet and its preparation method and application Download PDF

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CN105770296B
CN105770296B CN201610261610.6A CN201610261610A CN105770296B CN 105770296 B CN105770296 B CN 105770296B CN 201610261610 A CN201610261610 A CN 201610261610A CN 105770296 B CN105770296 B CN 105770296B
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chinese medicine
sachet
tranquilization
traditional chinese
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CN105770296A (en
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李冰石
徐陆周
陆为民
季春艳
严婷
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Jiangsu Provincial Hospital of Chinese Medicine
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009Sachets, pouches characterised by the material or function of the envelope

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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Abstract

The invention discloses a kind of Traditional Chinese medicine for tranquilization sachets, it includes the component of following parts by weight: 10~20 parts of Flos Albiziae, 8~15 parts of plum blossom, 8~15 parts of cortex cinnamomi, 8~15 parts of rhizoma cyperi, 8~15 parts of Rhizoma Chuanxiong, 8~15 parts of rhizoma acori graminei.The invention also discloses the preparation methods of above-mentioned Traditional Chinese medicine for tranquilization sachet and its application.Traditional Chinese medicine for tranquilization sachet of the invention is with the taste of drug, oral nasal inhalation, keeps passages through which vital energy circulates logical greatly, eliminating pathogen to support vital qi, the effect of to reach disease-relieving and physique enhancing.The therapeutic effect of Chinese medicine is than wide, calm, tranquilizing the mind can be played, especially have no peace of mind, Chinese medicine sedation becomes apparent and safety, sachet uses a variety of fragrant medicinal materials, and the drug in sachet gives out lasting aromatic odor, sucks respiratory tract, human respiratory tract mucosa is stimulated, drug absorption is made to work.Bedside is placed when sleep can effectively play sedative action.

Description

A kind of Traditional Chinese medicine for tranquilization sachet and its preparation method and application
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine sachet and its preparation method and application.
Background technique
Chinese medicine thinks that the body surface of people has fate row, and as the bodyguard of human body periphery, name defends gas, and defending gas is to take the photograph yang-energy admittedly, it In body surface, constantly transporting is walked.Gas row is defended daytime in the sun point of human body, is exactly row in yin at night then in row to yin point Through.As soon as people's sleepy is felt as long as yang-energy enters yin channel.It defends gas to have walked in yin channel, out in a flash from yin channel, people will wake up Come.Explanation here it is Chinese medicine to sleep mechanism.And artificially what can have a sleepless night? reason has three in simple terms: first is that heart kidney is not It hands over, second is that blood is insufficient, third is that liver-stomach disharmony.
Insomnia is frequently problem in clinical position, seems simple, actually not so, because insomnia is sometimes spiritual disease Disease such as depression, schizophrenic recurrence or the performance of the tendency of exacerbation, the sometimes First presentation of illness, therefore correct identification It has a sleepless night and gives corresponding treatment, be very helpful to the recovery of disease.Certainly, simple insomnia is also very common, Many times since patient lacks corresponding knowledge, worry that hypnotic can generate pharmacological dependence, thus dare not medication so that delaying Correctly treatment in time causes bigger pain to oneself and household.
The drug therapy having a sleepless night at present mainly has:
One, stabilizes class drug (benzodiazepine):
It is all stable class drug 1. all nomenclature of drug suffix are that west is dissolved or suffix is the drug of azoles logical sequence.
2. pharmacological dependence: including psychological dependence: thirsting for taking drugs in the depth of one's heart, even if not taking medicine, as long as there is medicine with it It will be very steady and sure.Body relies on: once not taking medicine, as having a sleepless night, agitation etc. can occur symptom originally again, there is also the heart Unbearably, nauseous, in terms of a variety of bodies such as perspiration symptom.
Two, third generation somnifacient: such as zolpidem, zopiclone, Zaleplon, eszopiclone.
Three, other drugs for improving insomnia: antipsychotics, antidepressant, antihistamine drug, Chinese patent drug etc..This Class drug is exactly familiar hypnotic, and fears the drug of habituation, and its advantages are that tranquilizing soporific effect is good, and price is just Preferably, the disadvantage is that side effect is bigger than normal, if wake up dizziness in the morning, muscle is powerless, is also easy to that daytime vigilance is caused to decline, cannot be engaged in Work as driving, long-term a large amount of uses are easy to produce pharmacological dependence.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of Traditional Chinese medicine for tranquilization sachets substantially without side-effects.
The present invention also technical problems to be solved are to provide the preparation method of above-mentioned Chinese medicine sachet.
The last technical problems to be solved of the present invention are to provide the application of above-mentioned Chinese medicine sachet.
In order to solve the above technical problems, The technical solution adopted by the invention is as follows:
A kind of Traditional Chinese medicine for tranquilization sachet, it includes the component of following parts by weight: 10~20 parts of Flos Albiziae, 8~15 parts of plum blossom, 8~15 parts of cortex cinnamomi, 8~15 parts of rhizoma cyperi, 8~15 parts of Rhizoma Chuanxiong, 8~15 parts of rhizoma acori graminei.
Above-mentioned Traditional Chinese medicine for tranquilization sachet preferably includes the component of following parts by weight: 15 parts of Flos Albiziae, 10 parts of plum blossom, cortex cinnamomi 10 parts, 8~15 parts of rhizoma cyperi, 10 parts of Rhizoma Chuanxiong, 10 parts of rhizoma acori graminei.
The preparation method of above-mentioned Traditional Chinese medicine for tranquilization sachet, by the Flos Albiziae of formula ratio, plum blossom, cortex cinnamomi, rhizoma cyperi, Rhizoma Chuanxiong and stone Chang Pu grinds to the powder and mixing of being sieved, and is fitted into non-woven bag and is made into sachet, and 15 grams every bag.
Wherein, the sieving is to sieve with 100 mesh sieve.
Above-mentioned Traditional Chinese medicine for tranquilization sachet prepare in spirit quieting medicine application it is also within the scope of the present invention.
Application of the above-mentioned Traditional Chinese medicine for tranquilization sachet in preparation rush sleep drug is also within the scope of the present invention.
Wherein, bedside is placed in sachet suggestion just before going to bed every night, is placed 7~8h and (when not used may be used until packing up when early morning gets up Wrapped up with polybag, prevent smell from volatilizing), the drug replaced in sachet is primary within every 7 days.
Flos Albiziae sweet in flavor and neutral in nature in side of the present invention, enters the heart, Liver Channel, is good at soothing liver-qi stagnation, for the key medicine for pleasing heart and tranquilizing mind;Plum blossom Fragrant promoting the circulation of qi enters liver stomach, and energy soothing liver-qi stagnation, in, relieve stagnation relieving restlessness, the two is monarch drug in a prescription for qi-regulating.The big heat of cortex cinnamomi enters liver kidney, can control Treat palpitaition, insomnia caused by the void of floating caused by declining because of lower first void;The pungent fragrant row of rhizoma cyperi dissipates, and bitter catharsis, master enters Liver Channel, is soothing the liver The key medicine of relieve stagnation, the two help are all ministerial drug with soothing liver-qi stagnation, tranquilizing the mind.The pungent fragrant row of Rhizoma Chuanxiong dissipates, and stagnation of QI due to depression of the liver is controlled in warm promoting blood circulation, It is simultaneous to control its mark, it is adjutant.Rhizoma acori graminei enters the heart channel of Hang-Shaoyin, happy key, and the function with inducing resuscitation intelligence development, hearing-improing and eyesight improving carries medicine uplink, so that medicine Enter the heart channel of Hang-Shaoyin in power, to make medicine.All medicine phases 5, gather the function of antitoxic heart-soothing and sedative altogether.
The utility model has the advantages that Traditional Chinese medicine for tranquilization sachet of the invention, with the taste of drug, oral nasal inhalation keeps passages through which vital energy circulates logical greatly, and eliminating evil is helped Just, to reach disease-relieving and physique enhancing the effect of.The therapeutic effect of Chinese medicine can play calm, tranquilizing the mind, the especially mind not than wide Rather, Chinese medicine sedation becomes apparent and safety, sachet use a variety of fragrant medicinal materials, and the drug in sachet gives out lasting Aromatic odor sucks respiratory tract, stimulates human respiratory tract mucosa, drug absorption is made to work.Placing bedside when sleep can be effective Play sedative action.
Specific embodiment
According to following embodiments, the present invention may be better understood.However, as it will be easily appreciated by one skilled in the art that real It applies content described in example and is merely to illustrate the present invention, without sheet described in detail in claims should will not be limited Invention.
Embodiment 1:
Traditional Chinese medicine for tranquilization sachet, the component including following parts by weight: 15 parts of Flos Albiziae, 10 parts of plum blossom, 10 parts of cortex cinnamomi, rhizoma cyperi 8~15 parts, 10 parts of Rhizoma Chuanxiong, 10 parts of rhizoma acori graminei.
The preparation method of above-mentioned Traditional Chinese medicine for tranquilization sachet, by the Flos Albiziae of formula ratio, plum blossom, cortex cinnamomi, rhizoma cyperi, Rhizoma Chuanxiong and stone Chang Pu grinds to the powder and sieves with 100 mesh sieve mixing, is fitted into non-woven bag, and 15 grams every bag.
Embodiment 2:
Traditional Chinese medicine for tranquilization sachet, the component including following parts by weight: 10 parts of Flos Albiziae, 8 parts of plum blossom, 8 parts of cortex cinnamomi, rhizoma cyperi 8 Part, 8 parts of Rhizoma Chuanxiong, 8 parts of rhizoma acori graminei.
The preparation method of above-mentioned Traditional Chinese medicine for tranquilization sachet, by the Flos Albiziae of formula ratio, plum blossom, cortex cinnamomi, rhizoma cyperi, Rhizoma Chuanxiong and stone Chang Pu grinds to the powder and sieves with 100 mesh sieve mixing, is fitted into non-woven bag, and 15 grams every bag.
Embodiment 3:
Traditional Chinese medicine for tranquilization sachet, the component including following parts by weight: 20 parts of Flos Albiziae, 15 parts of plum blossom, 15 parts of cortex cinnamomi, rhizoma cyperi 15 parts, 15 parts of Rhizoma Chuanxiong, 15 parts of rhizoma acori graminei.
The preparation method of above-mentioned Traditional Chinese medicine for tranquilization sachet, by the Flos Albiziae of formula ratio, plum blossom, cortex cinnamomi, rhizoma cyperi, Rhizoma Chuanxiong and stone Chang Pu grinds to the powder and sieves with 100 mesh sieve mixing, is fitted into non-woven bag, and 15 grams every bag.
Embodiment 4:
The insomniac for selecting 06 month 2015 to 03 month 2016 our hospital to accept for medical treatment totally 120, wherein male 62 (51.7%), women 58 (48.3%), the age 28~70 years old, average (63.40 ± 8.01) year, average course of disease (17.13 ± 2.67) moon.It is included according to definition in 2012 Chinese Adults insomnia Clinics and Practices guide and grade scale.It is included in standard: 1. Difficulty falling asleep refers to go to bed after cannot fall asleep within 30 minutes;2. maintaining dyscoimesis to refer to that night wakes up to turn 2 times or 2 times or more;3. total sleeps The time slept less than 6 hours.Sleep Evaluation index ranking criterion: 1. go to bed after cannot fall asleep within 50 minutes or more 4 points, go to bed after 40 points Clock cannot fall asleep 3 points, go to bed after cannot fall asleep within 30 minutes 2 points, go to bed after fall asleep within 30 minutes 1 point, go to bed after fall asleep 0 quickly Point;2. 4 points of night Xing Zhuan≤4 time, 3 points of night Xing Zhuan≤3 time, 2 points of night Xing Zhuan≤2 time, 1 point of night Xing Zhuan≤1 time, night Wake up turn < 1 time 0 point;3. 4 points total of sleeping time≤4 hour, 3 points total of sleeping time≤5 hour, total sleeping time≤6 are small When 2 divide, 1 point total of sleeping time >=6 hour, 0 point total of sleeping time >=8 hour.Use therapeutic evaluation after tranquilizing the mind sachet Index integrate >=4 points for invalid, evaluation index integrate 2~3 points be effectively, to integrate≤1 point be effective to evaluation index.Data collection Time: the medical same day, which collects, uses preceding all data, uses rear data using collecting at tranquilizing the mind sachet the 60th day.This research is all It is included in patient and uses tranquilizing the mind sachet, be used continuously 60 days, use 7~8h daily.As a result as follows:
The sleep quality table of comparisons [number of cases (percentage, %)] after 1 patient of table intervenes
The Sleep Evaluation index integral table of comparisons [number of cases (percentage, %)] before and after 2 patient's use of table
It is considerably better than as the result is shown using rear patient's sleep quality before use, concrete condition is shown in Table 1;As a result show simultaneously Using evaluation index integral after tranquilizing the mind sachet significantly lower than before use, concrete condition is shown in Table 2;It is obtained simultaneously by data analysis, Patient uses after tranquilizing the mind sachet obvious effective rate up to 42.4%, is efficient up to 45.8%, inefficiency 11.7%.

Claims (7)

1. a kind of Traditional Chinese medicine for tranquilization sachet, which is characterized in that it is grouped as by the group of following parts by weight:
10~20 parts of Flos Albiziae, 8~15 parts of plum blossom, 8~15 parts of cortex cinnamomi, 8~15 parts of rhizoma cyperi, 8~15 parts of Rhizoma Chuanxiong, rhizoma acori graminei 8~ 15 parts.
2. Traditional Chinese medicine for tranquilization sachet according to claim 1, which is characterized in that it is grouped as by the group of following parts by weight: 15 parts of Flos Albiziae, 10 parts of plum blossom, 10 parts of cortex cinnamomi, 8~15 parts of rhizoma cyperi, 10 parts of Rhizoma Chuanxiong, 10 parts of rhizoma acori graminei.
3. the preparation method of Traditional Chinese medicine for tranquilization sachet described in claim 1, which is characterized in that by the Flos Albiziae of formula ratio, plum blossom, Cortex cinnamomi, rhizoma cyperi, Rhizoma Chuanxiong and rhizoma acori graminei grind to the powder and mixing of being sieved, and is fitted into non-woven bag, and 15 grams every bag.
4. preparation method according to claim 3, which is characterized in that the sieving is to sieve with 100 mesh sieve.
5. Traditional Chinese medicine for tranquilization sachet described in claim 1 is preparing the application in spirit quieting medicine.
6. Traditional Chinese medicine for tranquilization sachet described in claim 1 promotees the application in sleep drug in preparation.
7. application according to claim 5 or 6, which is characterized in that place bedside just before going to bed every night, 7~8h is placed, until clear It is packed up when morning gets up, the drug in every 7 days replacement sachets is primary.
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CN111840455A (en) * 2020-08-06 2020-10-30 亳州益智健康产业有限公司 Nerve-soothing traditional Chinese medicine sachet and preparation method thereof
CN115814010A (en) * 2022-11-15 2023-03-21 上海中医药大学附属龙华医院 Traditional Chinese medicine composition for aiding sleep, sachet and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101721539A (en) * 2010-01-25 2010-06-09 西安交通大学 Traditional Chinese medicine sachet and preparation method thereof
CN101721609A (en) * 2010-01-25 2010-06-09 西安交通大学 Traditional Chinese medicine sachet for postoperative recovery and preparation method thereof
CN102430082A (en) * 2011-12-07 2012-05-02 黄炳炎 Traditional Chinese medicine sachet and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101721539A (en) * 2010-01-25 2010-06-09 西安交通大学 Traditional Chinese medicine sachet and preparation method thereof
CN101721609A (en) * 2010-01-25 2010-06-09 西安交通大学 Traditional Chinese medicine sachet for postoperative recovery and preparation method thereof
CN102430082A (en) * 2011-12-07 2012-05-02 黄炳炎 Traditional Chinese medicine sachet and preparation method thereof

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