CN104056230B - A kind of Chinese medicine composition for treating type of deficiency of both the heart and spleen insomnia - Google Patents
A kind of Chinese medicine composition for treating type of deficiency of both the heart and spleen insomnia Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine composition for treating insomnia, using Chinese medicines such as the Radix Astragali, Radix Angelicae Sinensis, Chinese cassia tree, honey-fried licorice root, ginseng, arillus longan, stir-baked SEMEN ZIZIPHI SPINOSAE, dates, liquid is obtained using traditional water decocting method to be used for patient, wherein with the Radix Astragali and arillus longan as monarch drug in a prescription, tonifying heart and spleen is played, the drug effect of nourishing blood and tranquilization, all medicines share can preferably play enriching spleen-QI, effect of the nourishing heart blood to calm the nerves, the insomnia to causing by the insufficiency of heart and spleen has splendid curative effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, and in particular to a kind of Chinese medicine composition for treating insomnia.
Background technology
Insomnia refers to that cannot fall asleep or cannot keep sleep state, causes sleep insufficiency.Hinder also known as falling asleep and maintaining to sleep
Hinder (D1MS), be that a variety of causes causes difficulty falling asleep, Depth of sleep or frequency be too short, early awakening and the length of one's sleep not enough or of poor quality
Deng being a kind of common disease.Insomnia often brings greatly pain and psychological burden to patient, again can be because abuse insomnia drug
And body other every aspects are damaged, though being not belonging to critical illness, people's normal life, work, study and healthy are hindered, and
Can aggravate or induce the illnesss such as palpitaition, the obstruction of qi in the chest, dizziness, headache, apoplexy.Obstinate insomnia, long-term pain is brought to patient
Hardship, or even the dependence to sleeping medicine is formed, and the sleeping medicine of long-term taking can cause iatrogenic disease, therefore be that the mankind need
One of major disease to be faced.
In existing treatment method, typically patient is helped to fall asleep using hypnotic, but take the sleep after hypnotic
Different from physiologic sleep, but passive sleep.Therefore, even if being fallen asleep whole night after medication, waking up, it is tired still feel, while such as
It is upper described, typically it is mostly in vivo that, by liver, renal metabolism, long-term taking can increase the negative of liver kidney due to hypnotic
Load, what is had can also cause liver enlargement, hepatalgia, jaundice, edema, albuminuria, blood urine and nausea, abdominal distension, poor appetite, just
It is secret to wait liver and kidney dysfunction and stomach reaction.Some hypnotics also result in the accumulation such as lassitude, hypophrenia, drop in blood pressure
Poisoning symptom, or even cause respiratory and circulatory function obstacle situation, therefore unsuitable long-term use, also cannot fundamentally play treatment
The purpose of insomnia.The traditional Chinese medical science thinks that insomnia can be divided into five types, and the wherein insufficiency of heart and spleen is a very common type, therefore
How one of the problem for needing to solve now is turned into treating insomnia with reference to the illness.
The content of the invention
For many weak points that existing medicament for treating insomnia is present, inventor manages with reference to traditional Chinese medicine
By, for type of deficiency of both the heart and spleen insomnia there is provided a kind of Chinese medicine composition of brand-new treatment insomnia, using the Radix Astragali, Radix Angelicae Sinensis, Chinese cassia tree,
The Chinese medicines such as honey-fried licorice root, ginseng, arillus longan, stir-baked SEMEN ZIZIPHI SPINOSAE, date, obtain liquid using traditional water decocting method makes for patient
With wherein with the Radix Astragali and arillus longan as monarch drug in a prescription, playing tonifying heart and spleen, the drug effect of nourishing blood and tranquilization, all medicines share can preferably rise
To enriching spleen-QI, effect of the nourishing heart blood to calm the nerves, the insomnia to causing by the insufficiency of heart and spleen has splendid curative effect.
The targeted insomnia of the present invention is mainly by the insufficiency of heart and spleen, caused by insufficiency of vital energy and blood:Heart storing spirit and main blood, the main think of of spleen and
System blood, ponders over overstrain, damages heart spleen;Taste are source of generating QI and blood, and insufficiency of the spleen then laboured breathing blood is few, and the heart is without supporting, it is impossible to hide
God, therefore be difficult to fall asleep, dreaming often and waking easily, palpitation and amnesia;Deficiency of qi and blood, lucid yang failing to raise, it is impossible to above give in brain, then have a dizzy spell.Blood
Void can not go up honor in face, therefore lustreless complexion;The dysfunction of the spleen in transport, it is impossible to transporting and transforming nutrients from foodstuff, then distaste for food, abdominal distension loose stool;The few deficiency of vital energy of blood,
Therefore lassitude, four limbs burnout, arteries and veins is thin and delicate;For above-mentioned disease, inventor controls ens morbi configuration and forms with reference to Traditional Chinese Medicine.
In parts by weight, its proportioning is each component of the medicine:Radix Astragali 13-15 parts, Radix Angelicae Sinensis 10-12 parts, Chinese cassia tree 6-8
Part, honey-fried licorice root 6-8 parts, ginseng 4-6 parts, fushen 10-12 parts, Ligusticum wallichii 8-10 parts, banksia rose 5-6 parts, bighead atractylodes rhizome 12-13 parts, polygala 7-9
Part, ginger 6-9 parts, arillus longan 11-14 parts, stir-baked SEMEN ZIZIPHI SPINOSAE 12-15 parts, date 7-9 parts.
Further, be optimized for for prescription by inventor:
15 parts of the Radix Astragali, 12 parts of Radix Angelicae Sinensis, 6 parts of Chinese cassia tree, 6 parts of honey-fried licorice root, 6 parts of ginseng, 12 parts of fushen, 9 parts of Ligusticum wallichii, 6 parts of the banksia rose,
12 parts of the bighead atractylodes rhizome, 9 parts of polygala, 6 parts of ginger, 12 parts of arillus longan, 15 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 9 parts of date.
The sweet tepor of the Radix Astragali in said components, return lung, the spleen channel are invigorated the spleen and benefited qi;The sweet temperature of arillus longan, the thoughts of returning home, the spleen channel can tonifying spleens
Gas, but energy nourishing heart blood is monarch drug in a prescription to calm the nerves, altogether;
The sweet temperature gas supplementing of ginseng, the bighead atractylodes rhizome, matches with the Radix Astragali, the work(that reinforcement is invigorated the spleen and benefited qi;The sweet pungent tepor of Radix Angelicae Sinensis, nourishing blood and nutrient QI,
With arillus longan phase 5, increase the effect of bushing blood-nourishing, be ministerial drug;
Fushen, spina date seed, polygala antitoxic heart-soothing and sedative;Muxiangliqi is amusing, Ligusticum wallichii blood-activating and qi-promoting, and benefiting qi and nourishing blood medicine compatibility,
Mend without stagnant, mend without hindering stomach;Chinese cassia tree is pungent sweet and hot, enters spleen, kidney, the heart, Liver Channel, can mends fire supporing yang, warming meridian, with the Radix Astragali,
The tonifying Qi and blood such as arillus longan medicine phases 5, inspire qi and blood growth, are all adjutant.
Honey-fried licorice root air making-up and spleen enlivening, coordinating the drug actions of a prescription, to make medicine;With ginger, date regulating spleen and stomach, conveniently taken as a means of biochemistry.
Simultaneously by adjusting the proportioning between each component, make full side's monarch clearly, compatibility purpose is rigorous, plays benefit
The effect of spleen QI invigorating, bushing blood-nourishing, can reduce side effects of pharmaceutical drugs with regulating spleen and stomach simultaneously, finally for type of deficiency of both the heart and spleen insomnia
There is good curative effect.
Compared with prior art, invention enhances the addition of the effectiveness of prescription blood-activating and qi-promoting, particularly rhizome of chuanxiong and Chinese cassia tree
With dose control, above-mentioned effect is realized, filled up the blank of prior art.
The specific decocting method of said medicine is:The medicine of recipe quantity is placed in marmite, is added water and is covered powder 2cm, soaked
Bubble 20 minutes, when being cooked by slow fire 100ml balance of to liquid, liquid is poured out, and then adding water again covers powder 2cm, slow fire
Decoct to the balance of 50ml of liquid;The dregs of a decoction can be filtered off, is merged filtering gained liquid twice and is obtained target liquid.
Amount of liquid in above-mentioned preparation method converts when being 1g according to weight portion in prescription.
The liquid patient obtained using the above method can directly be taken, and without the side effect of similar Western medicine, can make trouble
Person trusts and takes.
In sum, prescription provided by the present invention, selects medicine evident in efficacy to carry out with synthetic drug, full side the monarch and his subjects assistant
Make clearly, compatibility purpose is rigorous, plays tonifying heart and spleen, and the drug effect of nourishing blood and tranquilization, all medicines share can preferably play enriching spleen-QI,
Effect of the nourishing heart blood to calm the nerves, the insomnia to causing by the insufficiency of heart and spleen has splendid curative effect.
Specific embodiment
Embodiment 1
A kind of medicine for treating insomnia, in parts by weight, its proportioning is each component of the medicine:15 parts of the Radix Astragali, Radix Angelicae Sinensis
12 parts, 6 parts of Chinese cassia tree, 6 parts of honey-fried licorice root, 6 parts of ginseng, 12 parts of fushen, 9 parts of Ligusticum wallichii, 6 parts of the banksia rose, 12 parts of the bighead atractylodes rhizome, 9 parts of polygala, ginger
6 parts, 12 parts of arillus longan, 15 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 9 parts of date;Every part of 1g;
It is by decocting method:
The medicine of recipe quantity is placed in marmite, is added water and is covered powder 2cm, soaked 20 minutes, be cooked by slow fire to more than liquid
Measure during for 100ml, liquid is poured out, then adding water again covers powder 2cm, be cooked by slow fire to the balance of 50ml of liquid;
The dregs of a decoction are filtered off, is merged filtering gained liquid twice and is obtained target liquid.
Embodiment 2
A kind of medicine for treating insomnia, in parts by weight, its proportioning is each component of the medicine:13 parts of the Radix Astragali, Radix Angelicae Sinensis
10 parts, 7 parts of Chinese cassia tree, 8 parts of honey-fried licorice root, 4 parts of ginseng, 10 parts of fushen, 10 parts of Ligusticum wallichii, 6 parts of the banksia rose, 13 parts of the bighead atractylodes rhizome, 7 parts of polygala is raw
7 parts of ginger, 11 parts of arillus longan, 12 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 7 parts of date;Every part of 1g;
It is by decocting method:
The medicine of recipe quantity is placed in marmite, is added water and is covered powder 2cm, soaked 20 minutes, be cooked by slow fire to more than liquid
Measure during for 100ml, liquid is poured out, then adding water again covers powder 2cm, be cooked by slow fire to the balance of 50ml of liquid;
The dregs of a decoction are filtered off, is merged filtering gained liquid twice and is obtained target liquid.
Embodiment 3
A kind of medicine for treating insomnia, in parts by weight, its proportioning is each component of the medicine:14 parts of the Radix Astragali, Radix Angelicae Sinensis
11 parts, 8 parts of Chinese cassia tree, 7 parts of honey-fried licorice root, 5 parts of ginseng, 11 parts of fushen, 8 parts of Ligusticum wallichii, 5 parts of the banksia rose, 12 parts of the bighead atractylodes rhizome, 8 parts of polygala, ginger
8 parts, 14 parts of arillus longan, 13 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 8 parts of date;Every part of 1g;
It is by decocting method:
The medicine of recipe quantity is placed in marmite, is added water and is covered powder 2cm, soaked 20 minutes, be cooked by slow fire to more than liquid
Measure during for 100ml, liquid is poured out, then adding water again covers powder 2cm, be cooked by slow fire to the balance of 50ml of liquid;
The dregs of a decoction are filtered off, is merged filtering gained liquid twice and is obtained target liquid.
Embodiment 4
A kind of medicine for treating insomnia, in parts by weight, its proportioning is each component of the medicine:15 parts of the Radix Astragali, Radix Angelicae Sinensis
12 parts, 6 parts of Chinese cassia tree, 6 parts of honey-fried licorice root, 6 parts of ginseng, 12 parts of fushen, 9 parts of Ligusticum wallichii, 6 parts of the banksia rose, 12 parts of the bighead atractylodes rhizome, 9 parts of polygala, ginger
9 parts, 13 parts of arillus longan, 14 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 8 parts of date;Every part of 1g;
It is by decocting method:
The medicine of recipe quantity is placed in marmite, is added water and is covered powder 2cm, soaked 20 minutes, be cooked by slow fire to more than liquid
Measure during for 100ml, liquid is poured out, then adding water again covers powder 2cm, be cooked by slow fire to the balance of 50ml of liquid;
The dregs of a decoction are filtered off, is merged filtering gained liquid twice and is obtained target liquid.
Experimental example
Choose patient medical history totally 60.It is randomly divided into treatment group 30, control group 30.
Wherein patient works out with reference to State Administration of Traditional Chinese Medicine《Chinese medical disease Standardization of diagnosis and curative effect (1994)》In " no
Sleep " diagnostic criteria, be defined as type of deficiency of both the heart and spleen and be insomnia, that is, type of deficiency of both the heart and spleen insomnia.
Treatment group is treated using the medicine that embodiment 1 is obtained, and one portion per day is taken at twice;
Control group uses the Chinese mugwort department mile each 2mg of logical sequence, 1 times a day;
Medicine time is 6 weeks;
Criterion is as follows:
(1) clinical recovery:The length of one's sleep recovered normal or Nighttime sleep more than 6 hours, slept deep, essence after waking up
It is refreshing abundant;
(2) it is effective:Sleep is clearly better, and the length of one's sleep increases by more than 3 hours, and Depth of sleep increases;
(3) effectively:Symptom mitigation, the length of one's sleep increased less than 3 hours earlier above;
(4) it is invalid:Insomnia is not improved or instead adds severe one after treatment.
Evaluation of clinical curative effect such as following table after taking medicine 6 weeks:
By above-mentioned data, Chinese medicine provided by the present invention has splendid treatment for type of deficiency of both the heart and spleen insomnia
Effect, for the control group using western medicine, medicine of the invention is efficient higher, and can fundamentally cure mistake
Clinical recovery is realized in dormancy, and does not have the case of recovery from illness in control group, it is impossible to which the effect for reaching recovery from illness is only capable of realizing the mitigation of symptom,
It can be seen that Western medicine is only capable of playing the effect cured the symptoms, not the disease for the treatment of insomnia, with medicine effect provided by the present invention at a distance of very
Far, and medicine of the invention is free from side effects, will not be repeatedly after the drug dependence use without similar Chinese mugwort department mile logical sequence.
Claims (1)
- It is 1. a kind of to treat the Chinese medicine composition that type of deficiency of both the heart and spleen is had a sleepless night, it is characterised in that:The each component of the medicine is according to weight portion Count, its proportioning is:15 parts of the Radix Astragali, 12 parts of Radix Angelicae Sinensis, 6 parts of Chinese cassia tree, 6 parts of honey-fried licorice root, 6 parts of ginseng, 12 parts of fushen, 9 parts of Ligusticum wallichii, the banksia rose 6 parts, 12 parts of the bighead atractylodes rhizome, 9 parts of polygala, 6 parts of ginger, 12 parts of arillus longan, 15 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 9 parts of date;Its preparation method is as follows:By every part in prescription for 1g based on, the medicine of recipe quantity is placed in marmite, add water and cover powder 2cm, soak 20 minutes, text When fire decocts 100ml balance of to liquid, liquid is poured out, then adding water again covers powder 2cm, be cooked by slow fire to more than liquid It is 50ml to measure;The dregs of a decoction can be filtered off, is merged filtering gained liquid twice and is obtained target liquid.
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CN1823992A (en) * | 2005-12-15 | 2006-08-30 | 北京阜康仁生物制药科技有限公司 | Ginseny spleen invigorating preparation and its new preparation method |
WO2012027882A1 (en) * | 2010-08-30 | 2012-03-08 | 河北以岭医药研究院有限公司 | Pharmaceutical composition for treating insomnia and preparation method thereof |
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CN1823992A (en) * | 2005-12-15 | 2006-08-30 | 北京阜康仁生物制药科技有限公司 | Ginseny spleen invigorating preparation and its new preparation method |
WO2012027882A1 (en) * | 2010-08-30 | 2012-03-08 | 河北以岭医药研究院有限公司 | Pharmaceutical composition for treating insomnia and preparation method thereof |
Non-Patent Citations (1)
Title |
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加味归脾汤治疗失眠症50例;孙韶华等;《陕西中医》;20050225;第26卷(第02期);参见129页左侧栏"治疗方法" * |
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