CN105770062A - Medicine for treating nephrosis - Google Patents
Medicine for treating nephrosis Download PDFInfo
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- CN105770062A CN105770062A CN201610170534.8A CN201610170534A CN105770062A CN 105770062 A CN105770062 A CN 105770062A CN 201610170534 A CN201610170534 A CN 201610170534A CN 105770062 A CN105770062 A CN 105770062A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
Abstract
The invention relates to medicine for treating nephrosis. The medicine is prepared from the following effective raw material ingredients in parts by weight: 1 to 2 parts of hippocampus, 1 to 3 parts of rhizoma cibotii, 1 to 2 parts of Chinese teasel roots, 2 to 5 parts of eucommia barks, 1 to 3 parts of radix achyranthis bidentatae, 1 to 4 parts of pawpaw, 1 to 2 parts of radix angelicae sinensis and 3 to 10 parts of radix astragali seu hedysari. The medicine is obtained through matching pure traditional Chinese medicine, does not have toxic or side effects, and does not contain hormone; through the trying for many years, the medicine can be used for effectively curing various symptoms such as edema, urokinase protein, urine blood sugar and the like caused by nephrosis; the effects of enhancing the immunity, tonifying the kidney and benefiting Qi can be effectively achieved.
Description
Technical field
The present invention relates to technical field of Chinese medicines, especially a kind of medicine treating nephropathy.
Background technology
Nephropathy is one of common chronic disease of the mankind, these kinds of Diseases are various, the cause of disease is complicated, cure difficulty big, common nephropathy has glomerulonephritis, latent nephritis, pyelonephritis, Henoch Schonlein purpura nephritis, lupus erythematosus nephritis, gout kidney, nephrotic syndrome, membranous nephropathy, nephrotic syndrome, diabetic nephropathy, hypertensive nephropathy, polycystic kidney, etc., when the morbidity of these nephropathy delays difficulty more, time was more than three months, patient urine and relevant physiochemical indice occur abnormal, Renal Paphology, iconography notes abnormalities, or the glomerule effective filtration rate of kidney is lower than 60%, all can be collectively referred to as " chronic nephropathy ".Chronic nephropathy, as failed timely and effective treatment, causes that sb.'s illness took a turn for the worse and is in progress, then delay with the course of disease, Patients with Chronic Renal Disease will develop into chronic renal insufficiency, renal failure, ultimately forming uremia, patient not only to subject the misery of disease, and can cause great loss economically.
The treatment means that treatment nephropathy is the most frequently used at present is mainly western medicine, and severe patient row is dialysed or kidney transplantation treatment.Commonly used due to hormone and immunosuppressant in Western medicine, long-term taking is easy to make patient lead to complications, and brings new misery to patient.Dialysis and renal transplantation need to pay the medical expense of great number, and according to statistics, at present, China's renal transplantation existence time limit only has 5-7, although can temporarily extend the life-span of patient, but can not effect a radical cure, it is impossible to meet the requirement of patient.
Summary of the invention
The present invention is directed to above-mentioned the deficiencies in the prior art, it is provided that a kind of medicine treating nephropathy, this medicine adopts pure drug matching to form, and without hormone, has no side effect, and instant effect.
For solving above-mentioned technical problem, the technical solution used in the present invention is: a kind of medicine treating nephropathy, its effective raw material components includes Hippocampus, Rhizoma Cibotii, Radix Dipsaci, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Radix Angelicae Sinensis, the Radix Astragali, and the ratio of weight and number of said medicine is: Hippocampus 1 ~ 2 part, Rhizoma Cibotii 1 ~ 3 part, Radix Dipsaci 1 ~ 2 part, the Cortex Eucommiae 2 ~ 5 parts, Radix Achyranthis Bidentatae 1 ~ 3 part, Fructus Chaenomelis 1 ~ 4 part, Radix Angelicae Sinensis 1 ~ 2 part, the Radix Astragali 3 ~ 10 parts.
As preferably, a kind of medicine treating nephropathy, its effective raw material components includes Hippocampus, Rhizoma Cibotii, Radix Dipsaci, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Radix Angelicae Sinensis, the Radix Astragali, and the ratio of weight and number of said medicine is: Hippocampus 2 parts, Rhizoma Cibotii 3 parts, Radix Dipsaci 2 parts, the Cortex Eucommiae 4 parts, Radix Achyranthis Bidentatae 2 parts, Fructus Chaenomelis 4 parts, Radix Angelicae Sinensis 2 parts, the Radix Astragali 5 parts.
The preparation method of the present invention is: after being dried by Hippocampus, be ground into powder, loads in bag by 1.0 grams/bag；Respectively Hippocampus, Rhizoma Cibotii, Radix Dipsaci, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Radix Angelicae Sinensis, the Radix Astragali are made according to conventional method and exempt to decoct granule, load in bag by 1.0 grams/bag.
Oral method: ratio according to the rules when taking, pours into medicine in bowl, takes after mixing it with water with warm water, every day twice sooner or later, bfore meals.
The pharmacological effect of the adopted medicine of the present invention is:
Hippocampus: 1, Traditional Chinese Medicine theory is thought, Hippocampus sweet-salty, warm in nature, return Liver and kidney two warp, both kind kidney invigorating and YANG supporting benefit essence, control that the sexual impotence oligospermia of kidney yang deficiency, cold womb be infertile, frequent micturition, soreness of the waist and knees and suffering from a deficiency of the kidney is breathed heavily, again can blood circulation promoting and dispersing pathogen accumulation, reducing swelling and alleviating pain, controls note of the ancient Chinese abdominal mass and gathers, have the effects such as tranquillizing and allaying excitement concurrently.
2, Hippocampus has higher nutritive value and chemical active ingredient, and protein content is up to more than 70%, wherein with hippocampus trimaculatus Leacs the highest (73.56%).Hippocampus has 13 kinds of fatty acids, and unsaturated fatty acid accounts for the 65.18%～76.22% of total fatty acids, and wherein DHA content accounts for larger proportion.DHA is the main matter basis of prostate and sperm, and this provides foundation for this medical material kidney invigorating and YANG supporting effect.The total phospholipids of Hippocampus reaches 3.28～7.82mg/g and provides material base for its benefiting action.Hippocampus has Macro and trace elements more than 23 kinds, and in macroelement, Ca, P, K, Na, Mg content is all at more than 100mg/g, and wherein Mn, Zn content is higher, matches with its kidney invigorating and YANG supporting effect, and rich in Fe, also relevant with its nourishing liver and kidney, blood enriching and generation of vital essence promoting effect.
3, Hippocampus has hormone-like effect: the ethanol extract of kirschner Hippocampus can induce and extend the rutting period of female Mus, makes uterus and ovary weight increase, can make again male Mus prostate, seminal vesicle, levator ani weight substantially increase, show as Andrin-like action.The ethanol extraction of 5 kinds of Hippocampus all can increase sperm count and the sperm motility rate of Normal male mice to some extent, but on the gonad of normal mouse and sexual organ almost without impact, can substantially increase the weight of the sperm count of cyclophosphamide moulding mice, sperm survival rate and gonad, sexual organ.
4, Hippocampus also has delaying senility function: the water of Hippocampus, alcohol extract have promotion mice anti-stress effect, the memory ability of mice can be strengthened, increase the SOD content in Mouse Blood, the content (i.e. effect for reducing blood fat) of the lipid peroxide (LPO) in reduction Mouse Liver, suppress MAO-B activity in mouse brain, and promote that hemorheology changes and improves microcirculatory effect.The water of Hippocampus, alcohol extract have the effect promoting immune function of mice, increase the spleen weight of normal mouse and immune mouse, improve charcoal clearance and phagocytic index, improve peripheral blood lymphocyte ANAE positive percentage, promote the generation of Hemolysin, experiment in vitro can improve these experimental results of mice spleen lymphocytes proliferation, provides Important Theoretic Foundation for Hippocampus delaying senility function.
Rhizoma Cibotii: bitter in the mouth, sweet, warm in nature, return liver, kidney channel, there is effect of invigorating the liver and kidney, bone and muscle strengthening, the gas that reinforces the kidney.
Radix Dipsaci: bitter in the mouth, pungent, slightly warm in nature, return liver, kidney channel.There is promoting the circulation of blood detumescence, granulation promoting pain relieving, reunion of fractured tendons and bones, invigorating the liver and kidney, strong waist knee joint, antiabortive effect.
The Cortex Eucommiae: sweet in the mouth, warm in nature, there are liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, consolidate through antiabortive effect.The lumbago and skelalgia or aching and limp unable that insufficiency of kidney-YANG causes can be treated, the diseases such as born of the same parents' tire that deficiency of liver-QI causes is not solid, scrotum pruritus due to damp pathogen.
Radix Achyranthis Bidentatae: bitter in the mouth, sweet, sour, property is put down, and returns liver, kidney channel, has eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, effect of conducting blood to flow downwards.
Fructus Chaenomelis: sour in the mouth, warm in nature, enter liver, spleen channel；Have and help digestion, anthelmintic, heat clearing away, the effect dispeled the wind.
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature, return liver, the heart, spleen channel；Its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, invigorating middle warmer has, has benefit in row, and the gas medicine in sincere blood, also the panacea in blood is also.Then mending to mend of about assistant, therefore nutrition blood can be supported, QI invigorating spermatogenesis, settling five organs, strong body, benefit mind, all tangible deficient diseases, unsuitable without institute.
The Radix Astragali: sweet in the mouth, slightly warm in nature, return lung, spleen, liver, kidney channel.There are invigorating the spleen and replenishing QI, tonifying the lung consolidating superficial resistance, inducing diuresis to remove edema, evacuation of pus, effect of expelling pus and promoting granulation.The Radix Astragali is containing various trace elements such as Saponin, sucrose, polysaccharide, several amino acids, folic acid and selenium, zinc, copper.Have enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and wide antibacterial action.Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contraction, regulate blood sugar content.It is now widely used for chronic nephritis proteinuria, diabetes.
The beneficial effects of the present invention is: the present invention adopts pure drug matching to form, have no side effect, without hormone, attempt through for many years, can effectively cure the multinomial clinical indices such as edema that nephropathy causes, urine protein, serum creatinine are high, can effectively enhancing human body immunity power, tonify Qi of the kidney.
Detailed description of the invention
Hereinafter principles of the invention and feature being described, example is served only for explaining the present invention, is not intended to limit the scope of the present invention.
Embodiment 1
A kind of medicine treating nephropathy, its effective raw material components includes Hippocampus, Rhizoma Cibotii, Radix Dipsaci, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Radix Angelicae Sinensis, the Radix Astragali, and the ratio of weight and number of said medicine is: Hippocampus 2 parts, Rhizoma Cibotii 2 parts, Radix Dipsaci 2 parts, the Cortex Eucommiae 3 parts, Radix Achyranthis Bidentatae 2 parts, Fructus Chaenomelis 4 parts, Radix Angelicae Sinensis 2 parts, the Radix Astragali 5 parts.
Preparation method: after being dried by Hippocampus, be ground into powder, loads in bag by 1.0 grams/bag；Respectively Hippocampus, Rhizoma Cibotii, Radix Dipsaci, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Radix Angelicae Sinensis, the Radix Astragali are made according to conventional method and exempt to decoct granule, load in bag by 1.0 grams/bag.
Oral method: ratio according to the rules when taking, pours into medicine in bowl, takes after mixing it with water with warm water, every day twice sooner or later, bfore meals.
Embodiment 2
Clinical case 1
Chen, man, 51 years old, cadre.Address: Shanhaiguan District, Qinhuangdao.On November 12nd, 2015, first visit, main suit: find that albuminuria, serum creatinine, blood urea nitrogen raise 2 months.At Qinhuangdao 281 hospital admission, row kidney wears inspection, and pathological diagnosis is: moderate mesangial matrix * IgA nephropathy.Take (concrete consumption is not quite clear) treatments such as " benazepril " " amlodipine " " YESUAN PIAN ", without obvious curative effects.Inscribe disease: facial edema, dim complexion, soreness of waist pain, nocturia frequency, loose stool.Corpulent tongue, white and greasy fur, pulse condition is heavy thin.Tcm diagnosis: slow obstruction and rejection (negative and positive of qi and blood is all empty, and nephrons is deficient, and governor vessel, conception vessel meridians are obstructed).Western medicine diagnose: chronic nephritis, decompensation period of chronic renal failure, renal anemia.Method for the treatment of: benefiting QI and nourishing blood, Conception Vessel and Governor Vessel is led in the kidney invigorating.Every day takes Hippocampus 2 parts, Rhizoma Cibotii 2 parts, Radix Dipsaci 2 parts, the Cortex Eucommiae 3 parts, Radix Achyranthis Bidentatae 2 parts, Fructus Chaenomelis 4 parts, Radix Angelicae Sinensis 2 parts, the Radix Astragali 5 parts sooner or later.Adhering to taking February, lumbago symptom is substantially alleviated, and the index such as urine protein, renal function, anemia is clearly better.
Clinical case 2
Lee so-and-so, female, 62 years old, housework.Qinhuangdao waterfront area people.On October 15th, 2015, first visit.Previously type 2 diabetes mellitus medical history 12 years, starts subcutaneous insulin injections from JIUYUE, 2012, current insulin injection early 16U, late 12U, glycemic control situation: 6～8mmol/L, after the meal 8～14mmol/L on an empty stomach.Private prosecution waist and leg ache, face, double; two lower limbs edema, weak to breathe hard, pain is sent out in trick cool, and nocturia frequency is slept shallow, and poor appetite, tongue body is dim, pale, deep-thready pulse.Tcm diagnosis: diabetes diseases due to endogenous heat of ZANG FU organs phase.Western medicine diagnose: type 2 diabetes mellitus, diabetic nephropathy, diabetic peripheral neuropathy.Method for the treatment of: benefiting QI and nourishing blood, invigorating the liver and kidney, strong waist are superintended and directed.Every day is clothes sooner or later: Hippocampus 2 parts, Rhizoma Cibotii 3 parts, Radix Dipsaci 2 parts, the Cortex Eucommiae 5 parts, Radix Achyranthis Bidentatae 2 parts, Fructus Chaenomelis 3 parts, Radix Angelicae Sinensis 2 parts, the Radix Astragali 3 parts.Adhering to taking February, the soreness of waist is weak, face, double; two lower limbs edema symptom are substantially alleviated, and trick turns warm.Twenty-four-hour urine protein quantification reduces, and the index such as anemia, renal function is clearly better.
Claims (2)
1. the medicine treating nephropathy, it is characterized in that: its effective raw material components includes Hippocampus, Rhizoma Cibotii, Radix Dipsaci, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Radix Angelicae Sinensis, the Radix Astragali, the ratio of weight and number of said medicine is: Hippocampus 1 ~ 2 part, Rhizoma Cibotii 1 ~ 3 part, Radix Dipsaci 1 ~ 2 part, the Cortex Eucommiae 2 ~ 5 parts, Radix Achyranthis Bidentatae 1 ~ 3 part, Fructus Chaenomelis 1 ~ 4 part, Radix Angelicae Sinensis 1 ~ 2 part, the Radix Astragali 3 ~ 10 parts.
2. a kind of medicine treating nephropathy according to claim 1, it is characterized in that: a kind of medicine treating nephropathy, its effective raw material components includes Hippocampus, Rhizoma Cibotii, Radix Dipsaci, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Radix Angelicae Sinensis, the Radix Astragali, and the ratio of weight and number of said medicine is: Hippocampus 2 parts, Rhizoma Cibotii 3 parts, Radix Dipsaci 2 parts, the Cortex Eucommiae 4 parts, Radix Achyranthis Bidentatae 2 parts, Fructus Chaenomelis 4 parts, Radix Angelicae Sinensis 2 parts, the Radix Astragali 5 parts.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610170534.8A CN105770062A (en) | 2016-03-24 | 2016-03-24 | Medicine for treating nephrosis |
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| CN201610170534.8A CN105770062A (en) | 2016-03-24 | 2016-03-24 | Medicine for treating nephrosis |
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| CN105770062A true CN105770062A (en) | 2016-07-20 |
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| CN201610170534.8A Pending CN105770062A (en) | 2016-03-24 | 2016-03-24 | Medicine for treating nephrosis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115770266A (en) * | 2023-01-30 | 2023-03-10 | 云南中医药大学 | Pharmaceutical composition for improving bone mineral density based on regulation of intestinal bacteria metabolism |
Citations (4)
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|---|---|---|---|---|
| CN1562116A (en) * | 2004-03-26 | 2005-01-12 | 吉林敖东延边药业股份有限公司 | Chinese medicine preparation with invigorating kidney function |
| CN101380386A (en) * | 2008-09-18 | 2009-03-11 | 何官平 | Traditional Chinese medicine composition for tonifying the kidney yang |
| CN101897803A (en) * | 2009-05-27 | 2010-12-01 | 燕西营 | Chinese medicinal preparation for treating lumbago caused by deficiency of kidney essence |
| CN105012718A (en) * | 2015-07-09 | 2015-11-04 | 刘学勤 | Wine with functions of expelling cold, dispelling dampness and arresting arthralgia |
-
2016
- 2016-03-24 CN CN201610170534.8A patent/CN105770062A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1562116A (en) * | 2004-03-26 | 2005-01-12 | 吉林敖东延边药业股份有限公司 | Chinese medicine preparation with invigorating kidney function |
| CN101380386A (en) * | 2008-09-18 | 2009-03-11 | 何官平 | Traditional Chinese medicine composition for tonifying the kidney yang |
| CN101897803A (en) * | 2009-05-27 | 2010-12-01 | 燕西营 | Chinese medicinal preparation for treating lumbago caused by deficiency of kidney essence |
| CN105012718A (en) * | 2015-07-09 | 2015-11-04 | 刘学勤 | Wine with functions of expelling cold, dispelling dampness and arresting arthralgia |
Non-Patent Citations (1)
| Title |
|---|
| 柴瑞震: "《肾病中医食养方》", 31 January 2014 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115770266A (en) * | 2023-01-30 | 2023-03-10 | 云南中医药大学 | Pharmaceutical composition for improving bone mineral density based on regulation of intestinal bacteria metabolism |
| CN115770266B (en) * | 2023-01-30 | 2023-05-09 | 云南中医药大学 | Pharmaceutical composition for treating postmenopausal osteoporosis |
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