CN105749189A - Traditional Chinese medicine composition for treating cerebral thrombosis and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating cerebral thrombosis and preparation method of traditional Chinese medicine composition Download PDFInfo
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- CN105749189A CN105749189A CN201610321722.6A CN201610321722A CN105749189A CN 105749189 A CN105749189 A CN 105749189A CN 201610321722 A CN201610321722 A CN 201610321722A CN 105749189 A CN105749189 A CN 105749189A
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating cerebral thrombosis and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight: 2-6 parts of dried buthus martensii, 6-14 parts of centipede, 2-10 parts of earthworm, 5-15 parts of angelica sinensis, 12-20 parts of monkshood, 10-18 parts of myrrh, 10-22 parts of radix aconiti lateralis preparata, 7-13 parts of fructus evodiae, 4-13 parts of curcuma zedoary, 4-9 parts of cattail pollen, 3-12 parts of ligusticum wallichii, 6-12 parts of honeysuckle, 5-12 parts of astragalus membranaceus, 3-10 parts of tree peony bark, 15-25 parts of common peony roots and 8-15 parts of liquorice. Due to scientific computability of the components according to traditional Chinese medicine theories, and combination of the medicines, the traditional Chinese medicine composition provided by the invention has the effects of dredging collaterals and activating blood, tonifying spleen and nourishing qi, dissolving and removing thrombus, and the like, active components of the traditional Chinese medicines can be obtained through ethanol extraction and water decoction, and the traditional Chinese medicine composition is definite in treatment effect, free of side effect and remarkable in effect.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine composition treating cerebral thrombosis and system thereof
Preparation Method.
Background technology
Cerebrovascular disease is to currently exist in class commonly encountered diseases and the frequently-occurring disease in mid-aged population, has a strong impact on
The life of people also threatens human health.Cerebrovascular disease by its character can be divided into hemorrhagic apoplexy and
Ischemic cerebrovascular, ischemic cerebrovascular is the most common clinically, accounts for Changes of Patients With Cerebrovascular Diseases
70%-80%.Cerebral thrombosis is the modal type of cerebral infarction, belongs to ischemic cerebrovascular, is cerebral arteries master
Dry or cortical branches atherosclerosis causes Aldosterone, luminal stenosis inaccessible and thrombosis, causes brain office
Portion's Oligemia or blood supply are interrupted, and brain tissue ischemia anoxia causes softening the focal nervous system disease of downright bad appearance
Shape.Once had before morbidity that limbs are numb, it is ineffective to move, the sign such as slurred speech, dizziness and blurred vision.
Occurring time often in sleep or morning, patient activity is unable or stiff, speaks ambiguous, severe patient meeting
Hemiplegia or aphasia, drink water to send out and choke.
The modal cause of disease of cerebral thrombosis is arteriosclerosis, and due to cerebral arteriosclerosis, official jargon inner membrance is coarse,
Tube chamber narrows, and under certain conditions, blood pressure reduces, blood flow slows down or blood viscosity increases, platelet
Under the effect of the factors such as aggregation enhancing, thrombin coagulation in bulk in tube chamber, form thrombosis, make blood vessel
Obturation, blood flow interrupt, from but the brain tissue ischemia in blood vessel blood supply district, anoxia, softening, necrosis and fall ill.
The formation of cerebral thrombosis can occur at any one section of Ink vessel transfusing, clinically with internal carotid artery, anterior cerebral artery and
The thrombosis that the branch of middle cerebral artery is formed is more typically.Patient often shows central hemiplegia, facial paralysis and offside
Limbs are felt to go down.Most patient sanity, headache, vomiter are rare;But anterior cerebral artery or big
When the blocking of brain medium-sized artery trunk forms large area blocking, patient there will be the disease of disturbance of consciousness and increased intracranial pressure
Shape.Vertebral basilar system thrombosis, the motion of the most common dizziness, Nausea and vomiting, intercrossing and sensation
Obstacle, dysphagia, symptoms such as choking sent out by drinking-water.
Western medical treatment can be used, owing to Western medicine action target spot is single, for every kind of disease currently for above-mentioned disease
Become multi-medicament synergy such as using thrombolytic, neuroprotective, antiinflammatory, nutrition, costly, west in addition
Medical instrument has side effect, and gastrointestinal Liver and kidney can cause damage in various degree.Therefore having takes stopgap measures consolidates advantage
Chinese traditional treatment mode is widely used in cerebral thrombus patient, although achieves certain curative effect, but still there is curative effect
Slowly, the problem of the length course for the treatment of, therefore Chinese traditional treatment cerebral thrombosis disease needs reinforcement research.
Summary of the invention
The technical problem to be solved is: for the deficiency of the problems referred to above, it is provided that one treats brain blood
The Chinese medicine composition of bolt, this Chinese medicine composition determined curative effect, has no side effect, treats cerebral thrombosis and have notable effect
Really.
For solving above-mentioned technical problem, the technical scheme is that
A kind of Chinese medicine composition treating cerebral thrombosis, includes following component in parts by weight: Scorpio 2-6 part,
Scolopendra 6-14 part, Pheretima 2-10 part, Radix Angelicae Sinensis 5-15 part, Radix Aconiti 12-20 part, Myrrha 10-18 part, attached
Sub-10-22 part, Fructus Evodiae 7-13 part, Rhizoma Curcumae 4-13 part, Pollen Typhae 4-9 part, Rhizoma Chuanxiong 3-12 part, gold silver
Flower 6-12 part, Radix Astragali 5-12 part, Cortex Moutan 3-10 part, Radix Paeoniae Rubra 15-25 part and Radix Glycyrrhizae 8-15 part.
As the preferred technical scheme of one, include following component in parts by weight: Scorpio 3-5 part, Wu
Centipede 8-12 part, Pheretima 5-8 part, Radix Angelicae Sinensis 8-13 part, Radix Aconiti 15-18 part, Myrrha 13-16 part, Radix Aconiti Lateralis Preparata
14-20 part, Fructus Evodiae 9-12 part, Rhizoma Curcumae 7-12 part, Pollen Typhae 5-8 part, Rhizoma Chuanxiong 5-10 part, Flos Lonicerae
8-11 part, Radix Astragali 6-10 part, Cortex Moutan 5-8 part, Radix Paeoniae Rubra 18-23 part and Radix Glycyrrhizae 10-14 part.
To be solved by this invention another technical problem is that: provides a kind of Chinese medicine composition treating cerebral thrombosis
Preparation method, this preparation method is simple, easy to operate, the Chinese medicine composition determined curative effect of gained, without secondary
Effect, treatment cerebral thrombosis have remarkable result.
For solving above-mentioned technical problem, the technical scheme is that
The preparation method of a kind of Chinese medicine composition treating cerebral thrombosis, described preparation method comprises the following steps:
Step 1: first by Chinese crude drug Scorpio, Scolopendra, Pheretima, Radix Angelicae Sinensis, Radix Aconiti, Myrrha, Radix Aconiti Lateralis Preparata, Wu Zhu
Cornel, Rhizoma Curcumae, Pollen Typhae, Rhizoma Chuanxiong, Flos Lonicerae, the Radix Astragali, Cortex Moutan, Radix Paeoniae Rubra and Radix Glycyrrhizae are respectively washed, remove impurity,
It is dried, then according to weight portion weighs successively, adds relative to Chinese crude drug weight 8-12 times after pulverizing
The ethanol that volumetric concentration is 40-80%, impregnate 1-2h, reflux, extract, 2-3 time, merging filtrate, retain filter
Slag, obtains alcohol extraction concentrated solution;
Step 2: by adding water in above-mentioned filtering residue, soak 15-30 minute, decoct 2 times, merge decoction liquor,
Obtain water extracting liquid;
Step 3: the water extracting liquid mix homogeneously that alcohol extraction concentrated solution step 1 obtained and step 2 obtain,
It is concentrated to give powdered extract, pulverizes, sieve, add adjuvant and make Chinese medicine.
As the technical scheme of a kind of improvement, first described Myrrha is picked up clean remove impurity, is broken into little
Grain or corase meal, then Rhizoma Cyperi powder is placed in pot first with slow fire fry, after fry with high heat, place into after making popular
Myrrha stirs, and fries and rises to dense smoke, in taupe, foam crisp, takes out, dry in the air cool.
As the technical scheme of a kind of improvement, alcohol extraction concentrated solution and the mixing of water extracting liquid in described step 3
Temperature is 50-65 DEG C.
After have employed technique scheme, the invention has the beneficial effects as follows:
Chinese medicine composition of the present invention selects Scorpio, Scolopendra, Pheretima, Radix Angelicae Sinensis, Radix Aconiti, Myrrha, Radix Aconiti Lateralis Preparata, Wu
The Fructus Evodiae, Rhizoma Curcumae, Pollen Typhae, Rhizoma Chuanxiong, Flos Lonicerae, the Radix Astragali, Cortex Moutan, Radix Paeoniae Rubra and 16 Chinese crude drug systems of Radix Glycyrrhizae
Become.Wherein Scorpio property is flat, acrid in the mouth, poisonous, returns Liver Channel, has endogenous wind stopping spasmolytic, dispersing pathogen accumulation, and dredging collateral is only
Effect of pain;Scolopendra is warm in nature, salty in the mouth, pungent, poisonous, returns liver, spleen, lung meridian, has relieving spasm by calming endogenous wind, attacks
Poison eliminating stagnation, effect of removing obstruction in the collateral to relieve pain;Pheretima is cold in nature, salty in the mouth;Return liver, spleen, bladder warp;There is heat clearing away fixed
Frightened, dredging collateral, suppressing the hyperactive liver, effect of cough-relieving;Radix Angelicae Sinensis is warm in nature, sweet in the mouth, pungent;Return liver, the heart, spleen channel;Have
Replenishing and activating blood, effect of menstruction regulating and pain relieving;Radix Aconiti property heat, acrid in the mouth, hardship;Very toxic;GUIXIN, liver, kidney,
Spleen channel.There is expelling wind and removing dampness, antalgic.No mild in medicine property, bitter in the mouth is nontoxic.Return liver, spleen, the heart, kidney
Warp;There is promoting blood circulation to remove blood stasis, effect of circulation of qi promoting relaxing muscles and tendons;Radix Aconiti Lateralis Preparata is sweet, acrid in the mouth, the hottest, poisonous, GUIXIN,
Kidney, spleen channel, have recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, effect of dispersing cold for relieving pain;Fructus Evodiae is pungent, bitter in the mouth,
Heat;Slightly poisonous;Return liver, spleen, stomach, kidney channel.There is dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, the merit of supporing yang antidiarrheal
Effect.Rhizoma Curcumae is warm in nature, bitter in the mouth, pungent;Return liver, spleen channel.There is removing blood stasis circulation of qi promoting, effect of removing food stagnancy pain relieving;Pu
Huang Xingping, sweet in the mouth;Return liver, pericardium channel;There is hemostasis with astringents, promoting the circulation of blood blood stasis dispelling;Rhizoma Chuanxiong is warm in nature, acrid in the mouth;
Return liver, gallbladder, pericardium channel;There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping;Flos Lonicerae is cold in nature, sweet in the mouth, enters
Lung, the heart, stomach warp, have heat-clearing and toxic substances removing, antiinflammatory, effect of qi-restoratives treatment wind;The Radix Astragali is warm in nature, sweet in the mouth;Tool
Tonifying Qi and lifting yang, benefit is had to defend consolidating superficial resistance, detoxification granulation promoting, effect of diuretic detumescent;Cortex Moutan cold nature, bitter in the mouth,
Pungent, GUIXIN, liver, kidney, lung meridian, there is effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis;Radix Paeoniae Rubra cold nature, taste
Hardship, returns Liver Channel, has clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling;Radix Glycyrrhizae property is put down, and sweet in the mouth returns 12 warps.
There are the pharmacological actions such as removing toxic substances, blood stasis dispelling, pain relieving, spasmolytic.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, relieving cough and moistening lung,
Emergency is detoxified, and can be in harmonious proportion hundred medicines.
The traditional Chinese medical science thinks that cerebral thrombosis is vigour loss, stagnation of blood stasis venation, or deficiency of YIN the moon gas, and the expectorant stasis of blood hands over resistance meridians,
Ailment said due to cold or exposure enters caused.Chinese medicine composition of the present invention share according to theory of Chinese medical science scientific compatibility, all medicines, has logical
The effects such as network is invigorated blood circulation, invigorating the spleen and replenishing QI, thrombolytic, logical bolt;Alcohol reflux and soak by water is used to obtain above-mentioned
The alcohol extraction active component of Chinese crude drug and water carry active component, use it for cerebral thrombus patient, determined curative effect, nothing
Side effect, effect are notable.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with embodiment,
The present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to
Explain the present invention, be not intended to limit the present invention.
Embodiment 1
A kind of Chinese medicine composition treating cerebral thrombosis, counts according to weight portion (g) and includes following component: Scorpio 2g,
Scolopendra 6g, Pheretima 2g, Radix Angelicae Sinensis 5g, Radix Aconiti 12g, Myrrha 10g, Radix Aconiti Lateralis Preparata 10g, Fructus Evodiae 7g, Rhizoma Curcumae
4g, Pollen Typhae 4g, Rhizoma Chuanxiong 3g, Flos Lonicerae 6g, Radix Astragali 5g, Cortex Moutan 3g, Radix Paeoniae Rubra 15g and Radix Glycyrrhizae 8g.
Embodiment 2
A kind of Chinese medicine composition treating cerebral thrombosis, counts according to weight portion (g) and includes following component: Scorpio 3g,
Scolopendra 8g, Pheretima 5g, Radix Angelicae Sinensis 8g, Radix Aconiti 15g, Myrrha 13g, Radix Aconiti Lateralis Preparata 14g, Fructus Evodiae 9g, Rhizoma Curcumae
7g, Pollen Typhae 5g, Rhizoma Chuanxiong 5g, Flos Lonicerae 8g, Radix Astragali 6g, Cortex Moutan 5g, Radix Paeoniae Rubra 18g and Radix Glycyrrhizae 10g.
Its preparation method comprises the following steps:
Step 1: first by Chinese crude drug Scorpio, Scolopendra, Pheretima, Radix Angelicae Sinensis, Radix Aconiti, Myrrha, Radix Aconiti Lateralis Preparata, Wu Zhu
Cornel, Rhizoma Curcumae, Pollen Typhae, Rhizoma Chuanxiong, Flos Lonicerae, the Radix Astragali, Cortex Moutan, Radix Paeoniae Rubra and Radix Glycyrrhizae are respectively washed, remove impurity,
It is dried, then according to weight portion weighs successively, adds relative to Chinese crude drug weight 8 times after pulverizing
Volumetric concentration is the ethanol of 40%, impregnates 2h, reflux, extract, 2 times, merging filtrate, retains filtering residue, obtain
Alcohol extraction concentrated solution;
Step 2: by adding water in above-mentioned filtering residue, soak 15 minutes, decoct 2 times, merge decoction liquor,
To water extracting liquid;
Step 3: the water extracting liquid mix homogeneously that alcohol extraction concentrated solution step 1 obtained and step 2 obtain,
Mixing temperature is 50 DEG C, is concentrated to give powdered extract, pulverizes, crosses 120 mesh sieves, makes powder.
Wherein first Myrrha is picked up clean remove impurity, is broken into little granule or corase meal, then by Rhizoma Cyperi powder
Be placed in pot first with slow fire fry, after fry with high heat, place into Myrrha after making popular and stir, fry to dense smoke rise,
In taupe, foam crisp, take out, dry in the air cool.
Embodiment 3
A kind of Chinese medicine composition treating cerebral thrombosis, counts according to weight portion (g) and includes following component: Scorpio 4g,
Scolopendra 10g, Pheretima 7g, Radix Angelicae Sinensis 10g, Radix Aconiti 17g, Myrrha 15g, Radix Aconiti Lateralis Preparata 18g, Fructus Evodiae 11g, cowherb
Art 10g, Pollen Typhae 7g, Rhizoma Chuanxiong 8g, Flos Lonicerae 10g, Radix Astragali 9g, Cortex Moutan 7g, Radix Paeoniae Rubra 21g and Radix Glycyrrhizae
12g。
Its preparation method comprises the following steps:
Step 1: first by Chinese crude drug Scorpio, Scolopendra, Pheretima, Radix Angelicae Sinensis, Radix Aconiti, Myrrha, Radix Aconiti Lateralis Preparata, Wu Zhu
Cornel, Rhizoma Curcumae, Pollen Typhae, Rhizoma Chuanxiong, Flos Lonicerae, the Radix Astragali, Cortex Moutan, Radix Paeoniae Rubra and Radix Glycyrrhizae are respectively washed, remove impurity,
It is dried, then according to weight portion weighs successively, adds relative to Chinese crude drug weight 10 times after pulverizing
Volumetric concentration is the ethanol of 60%, impregnates 1.5h, reflux, extract, 3 times, merging filtrate, retains filtering residue,
To alcohol extraction concentrated solution;
Step 2: by adding water in above-mentioned filtering residue, soak 25 minutes, decoct 2 times, merge decoction liquor,
To water extracting liquid;
Step 3: the water extracting liquid mix homogeneously that alcohol extraction concentrated solution step 1 obtained and step 2 obtain,
Mixing temperature is 55 DEG C, is concentrated to give powdered extract, pulverizes, crosses 100 mesh sieves, adds starch, encapsulated,
Make capsule.
Embodiment 4
A kind of Chinese medicine composition treating cerebral thrombosis, counts according to weight portion (g) and includes following component: Scorpio 5g,
Scolopendra 12g, Pheretima 8g, Radix Angelicae Sinensis 13g, Radix Aconiti 16g, Myrrha 16g, Radix Aconiti Lateralis Preparata 20g, Fructus Evodiae 12g, cowherb
Art 12g, Pollen Typhae 8g, Rhizoma Chuanxiong 10g, Flos Lonicerae 11g, Radix Astragali 10g, Cortex Moutan 8g, Radix Paeoniae Rubra 23g and sweet
Grass 14g.
Its preparation method comprises the following steps:
Step 1: first by Chinese crude drug Scorpio, Scolopendra, Pheretima, Radix Angelicae Sinensis, Radix Aconiti, Myrrha, Radix Aconiti Lateralis Preparata, Wu Zhu
Cornel, Rhizoma Curcumae, Pollen Typhae, Rhizoma Chuanxiong, Flos Lonicerae, the Radix Astragali, Cortex Moutan, Radix Paeoniae Rubra and Radix Glycyrrhizae are respectively washed, remove impurity,
It is dried, then according to weight portion weighs successively, adds relative to Chinese crude drug weight 12 times after pulverizing
Volumetric concentration is the ethanol of 80%, impregnates 1h, reflux, extract, 3 times, merging filtrate, retains filtering residue, obtain
Alcohol extraction concentrated solution;
Step 2: by adding water in above-mentioned filtering residue, soak 30 minutes, decoct 2 times, merge decoction liquor,
To water extracting liquid;
Step 3: the water extracting liquid mix homogeneously that alcohol extraction concentrated solution step 1 obtained and step 2 obtain,
Mixing temperature is 60 DEG C, is concentrated to give powdered extract, pulverizes, crosses 80 mesh sieves, makes pill.
Embodiment 5
A kind of Chinese medicine composition treating cerebral thrombosis, counts according to weight portion (g) and includes following component: Scorpio 6g,
Scolopendra 14g, Pheretima 10g, Radix Angelicae Sinensis 15g, Radix Aconiti 20g, Myrrha 18g, Radix Aconiti Lateralis Preparata 22g, Fructus Evodiae 13g,
Rhizoma Curcumae 13g, Pollen Typhae 9g, Rhizoma Chuanxiong 12g, Flos Lonicerae 12g, Radix Astragali 12g, Cortex Moutan 10g, Radix Paeoniae Rubra 25g
With Radix Glycyrrhizae 15g.
Its preparation method comprises the following steps:
Step 1: first by Chinese crude drug Scorpio, Scolopendra, Pheretima, Radix Angelicae Sinensis, Radix Aconiti, Myrrha, Radix Aconiti Lateralis Preparata, Wu Zhu
Cornel, Rhizoma Curcumae, Pollen Typhae, Rhizoma Chuanxiong, Flos Lonicerae, the Radix Astragali, Cortex Moutan, Radix Paeoniae Rubra and Radix Glycyrrhizae are respectively washed, remove impurity,
It is dried, then according to weight portion weighs successively, adds relative to Chinese crude drug weight 12 times after pulverizing
Volumetric concentration is the ethanol of 70%, impregnates 1.5h, reflux, extract, 3 times, merging filtrate, retains filtering residue,
To alcohol extraction concentrated solution;
Step 2: by adding water in above-mentioned filtering residue, soak 30 minutes, decoct 2 times, merge decoction liquor,
To water extracting liquid;
Step 3: the water extracting liquid mix homogeneously that alcohol extraction concentrated solution step 1 obtained and step 2 obtain,
Mixing temperature is 60 DEG C, is concentrated to give powdered extract, pulverizes, crosses 120 mesh sieves, adds starch, encapsulated,
Make capsule.
Above-mentioned Chinese medicine composition is in preparation process, and first Chinese crude drug Myrrha is picked up clean remove impurity, smashed
Become little granule or corase meal, then Rhizoma Cyperi powder is placed in pot first with slow fire fry, after fry with high heat, after making popular
Place into Myrrha to stir, fry and rise to dense smoke, in taupe, foam crisp, take out, dry in the air cool.
Embodiment 6 Chinese medicine composition of the present invention is to cerebral thrombus patient's observation of curative effect
1. case collection: select 200 example cerebral thrombus patients, is randomly divided into experimental group and matched group, often organizes 100
Example, wherein experimental group male 65 example, women 35 example;Matched group male 73 example, women 27 example.
2. Therapeutic Method: experimental group takes the preparation that above-mentioned Chinese medicine composition is developed, and twice on the one, divides sooner or later
Take;Matched group takes XUESHUANXINMAINING, three times a day, and each two panels.
3. curative effect judgment criteria:
1) cure: transference cure, general physical exertion can be engaged in;
2) effective: symptom major part disappears, and takes care of oneself;
3) take a turn for the better: symptom major part takes a turn for the better, be relatively improved in varying degrees before treatment;
4) invalid: before and after's symptom of being admitted to hospital is not any change.
4. result of the test:
Experimental group cures 31 examples, effective 36 examples, and take a turn for the better 25 examples, invalid 8 examples, total effective rate 92%;Right
Curing 26 examples according to group, effective 31 examples, take a turn for the better 23 examples, invalid 20 examples, total effective rate 80%.Result of the test
Show that the traditional Chinese medicine composition for treating cerebral thrombosis effect using the present invention is more effective than matched group.
Embodiment 7 typical case
Case 1
Patient Wang, female, 53 years old, cerebral thrombosis was admitted to hospital, and two an eye line obscure, bradyphrenia, took after being in hospital
With above-mentioned Chinese medicinal composition capsules agent, after taking three courses for the treatment of, above-mentioned symptom disappears.Continue to take a treatment
Cheng Hou, is discharged from hospitals upon recovery, and has no recurrence in 1 year.
Case 2
Patient poplar, female, 62 years old, bimester before suddenly mouth askew, sialorrhea;Left half body inconvenient activity, speaks
Ambiguous.After taking two courses for the treatment of of Chinese medicine composition pill of the present invention, left half body can be movable, then takes
After two courses for the treatment of, walk without crutch, and lamprophonia, not sialorrhea, have no recurrence in two years.
Case 3
Patient Zhang, man, 48 years old, happened suddenly cerebral thrombosis, and right upper extremity activity is ineffective, slurred speech, through taking
After three courses for the treatment of of above-mentioned Chinese medicine composition composition powders, right upper extremity activity freely, lamprophonia, have no multiple in 1 year
Send out.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all at this
Any amendment, equivalent and the improvement etc. made within bright spirit and principle, should be included in the present invention
Protection domain within.
Claims (5)
1. the Chinese medicine composition treating cerebral thrombosis, it is characterised in that: include following group in parts by weight
Point: Scorpio 2-6 part, Scolopendra 6-14 part, Pheretima 2-10 part, Radix Angelicae Sinensis 5-15 part, Radix Aconiti 12-20 part,
Myrrha 10-18 part, Radix Aconiti Lateralis Preparata 10-22 part, Fructus Evodiae 7-13 part, Rhizoma Curcumae 4-13 part, Pollen Typhae 4-9 part,
Rhizoma Chuanxiong 3-12 part, Flos Lonicerae 6-12 part, Radix Astragali 5-12 part, Cortex Moutan 3-10 part, Radix Paeoniae Rubra 15-25 part
With Radix Glycyrrhizae 8-15 part.
A kind of Chinese medicine composition treating cerebral thrombosis the most according to claim 1, it is characterised in that: press
Following component is included: Scorpio 3-5 part, Scolopendra 8-12 part, Pheretima 5-8 part, Radix Angelicae Sinensis 8-13 according to weight portion meter
Part, Radix Aconiti 15-18 part, Myrrha 13-16 part, Radix Aconiti Lateralis Preparata 14-20 part, Fructus Evodiae 9-12 part, Rhizoma Curcumae 7-12
Part, Pollen Typhae 5-8 part, Rhizoma Chuanxiong 5-10 part, Flos Lonicerae 8-11 part, Radix Astragali 6-10 part, Cortex Moutan 5-8 part,
Radix Paeoniae Rubra 18-23 part and Radix Glycyrrhizae 10-14 part.
3. the preparation method of the Chinese medicine composition treating cerebral thrombosis, it is characterised in that described preparation method bag
Include the following step:
Step 1: first by Chinese crude drug Scorpio, Scolopendra, Pheretima, Radix Angelicae Sinensis, Radix Aconiti, Myrrha, Radix Aconiti Lateralis Preparata, Wu Zhu
Cornel, Rhizoma Curcumae, Pollen Typhae, Rhizoma Chuanxiong, Flos Lonicerae, the Radix Astragali, Cortex Moutan, Radix Paeoniae Rubra and Radix Glycyrrhizae are respectively washed, remove impurity,
It is dried, then according to weight portion weighs successively, adds relative to Chinese crude drug weight 8-12 times after pulverizing
The ethanol that volumetric concentration is 40-80%, impregnate 1-2h, reflux, extract, 2-3 time, merging filtrate, retain filter
Slag, obtains alcohol extraction concentrated solution;
Step 2: by adding water in above-mentioned filtering residue, soak 15-30 minute, decoct 2 times, merge decoction liquor,
Obtain water extracting liquid;
Step 3: the water extracting liquid mix homogeneously that alcohol extraction concentrated solution step 1 obtained and step 2 obtain,
It is concentrated to give powdered extract, pulverizes, sieve, add adjuvant and make Chinese medicine.
A kind of Chinese medicine composition preparation method treating cerebral thrombosis the most according to claim 3, its feature
It is: first described Myrrha is picked up clean remove impurity, is broken into little granule or corase meal, then by Rhizoma Cyperi
Powder be placed in pot first with slow fire fry, after fry with high heat, place into Myrrha after making popular and stir, fry to dense smoke rise,
In taupe, foam crisp, take out, dry in the air cool.
A kind of Chinese medicine composition preparation method treating cerebral thrombosis the most according to claim 3, its feature
It is: in described step 3, the mixing temperature of alcohol extraction concentrated solution and water extracting liquid is 50-65 DEG C.
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金龙学等: "《中西医结合治疗75例脑梗塞临床疗效观察》", 《中医药学报》 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106266975A (en) * | 2016-09-07 | 2017-01-04 | 广东伊茗药业有限公司 | A kind of medicine of the treatment cerebral thrombosis containing Rhizoma Acori Graminei |
CN108299348A (en) * | 2018-02-09 | 2018-07-20 | 广东药科大学 | A kind of purposes of moutan bark carbon new natural product in preparing anticoagulation medicine |
CN108299348B (en) * | 2018-02-09 | 2021-06-22 | 广东药科大学 | Application of cortex moutan charcoal natural product in preparation of anticoagulant |
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