CN105748961A - 一种治疗癫痫的中药组合物 - Google Patents

一种治疗癫痫的中药组合物 Download PDF

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CN105748961A
CN105748961A CN201610306971.8A CN201610306971A CN105748961A CN 105748961 A CN105748961 A CN 105748961A CN 201610306971 A CN201610306971 A CN 201610306971A CN 105748961 A CN105748961 A CN 105748961A
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俞成莲
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Abstract

本发明公开了一种治疗癫痫的中药组合物，由下述重量份配比的原料制成：决明子1015份，紫石英57份，钩藤1015份，茯苓1015份，菖蒲68份，远志812份，栀子57份，法半夏57份，胆南星68份，柴胡812份，天麻1015份，川贝57份，陈皮1012份，大黄35份。本发明治疗癫痫的中药组合物，选取14种天然中药科学配伍，配方简单，各原料药协同作用起到清心镇惊、清热解毒、安神助眠的效果，见效快，标本兼治，无毒副作用，而且其制备方法简单、服用方便，成本低。有效率达到97.8%以上。

Description

一种治疗癫痫的中药组合物
技术领域
本发明涉及中药，具体是一种治疗癫痫的中药组合物。
背景技术
癫痫即俗称的“羊角风”或“羊癫风”，是由于大脑神经元突发性异常放电，而导致短暂的大脑功能障碍的一种慢性疾病。由于异常放电的起始部位和传递方式的不同，癫痫发作的临床表现复杂多样，可表现为发作性运动、感觉、自主神经、意识及精神障碍。引起癫痫的病因多种多样。癫痫患者经过正规的抗癫痫药物治疗，约70%的患者其发作是可以得到控制的，其中50%～60%的患者经2-5年的治疗可以痊愈，患者可以和正常人一样地工作和生活。
癫痫可见于各个年龄段。儿童癫痫发病率较成人高，随着年龄的增长，癫痫发病率有所降低。进入老年期(65岁以后)由于脑血管病、老年痴呆和神经系统退行性病变增多，癫痫发病率又见上升。由于异常放电的起始部位和传递方式的不同，癫痫发作的临床表现复杂多样。
现有的治疗方法多主要是以药物治疗为主，还有病因治疗、外科治疗等方法，不仅副作用大，且不能完全治愈，容易复发，对患者经济和生理造成一定的负担。而目前的一些中药的治疗效率也不甚理想，治疗周期长，且疗效不显著。
发明内容
本发明的目的是提供一种疗效好、疗程短、成本低、无毒副作用的治疗癫痫的中药组合物。
实现本发明目的的技术方案是：
一种治疗癫痫的中药组合物，由下述重量份配比的原料制成：
决明子10-15份，紫石英5-7份，钩藤10-15份，茯苓10-15份，菖蒲6-8份，远志8-12份，栀子5-7份，法半夏5-7份，胆南星6-8份，柴胡8-12份，天麻10-15份，川贝5-7份，陈皮10-12份，大黄3-5份。
上述治疗癫痫的中药组合物，各原料的最佳重量份配比为：
决明子12份，紫石英6份，钩藤12份，茯苓12份，菖蒲7份，远志10份，栀子6份，法半夏6份，胆南星7份，柴胡10份，天麻12份，川贝6份，陈皮11份，大黄4份。
所述的原料药材在中药店及市场有售。
本发明药物的制备方法如下：按重量配比称取各原料，加入混合置于容器中，再加原料量重量8-12倍的水煎煮4次，每次用2-3倍的水煎煮40-50min，合并煎煮液，过滤去渣，滤液浓缩至50-60℃下相对密度为1.30-1.40g的浸膏，加入辅料，制成相应的剂型，即得。
本发明中，各原料药的药理、功效如下：
决明子：具清热明目、润肠通便的功能。生决明子长于清肝热，润肠燥。用于目赤肿痛，大便秘结。
紫石英：镇心；安神；降逆气；暖子宫。主治：心悸；怔忡；惊痫；肺寒咳逆上气；女子宫寒不孕。
栀子：泻火除烦；清热利湿；凉血解毒；焦栀子：凉血止血。主治：热病心烦；肝火目赤；头痛；湿热黄疸；淋证；血痢尿血；口舌生疮；疮疡肿毒；扭伤肿痛。
柴胡：透表泄热，疏肝解郁，升举阳气。主治：肝郁气滞，胸肋胀痛，脱肛，子宫脱落，月经不调。
川贝：润肺止咳化痰平喘，清热化痰。
大黄：实热便秘；热结胸痞；湿热泻痢；黄疸；淋病；水肿腹满；小便不利；目赤；咽喉肿痛；口舌生疮；胃热呕吐；吐血；咯血；衄血；便血；尿血；蓄血；经闭；产后瘀滞腹痛；症瘕积聚；跌打损伤；热毒痈疡；丹毒；烫伤。
天麻：息风，定惊。治眩晕眼黑，头风头痛，肢体麻木，半身不遂，语言蹇涩，小儿惊痫动风。
陈皮：理气健脾，燥湿化痰。用于脘腹胀满，食少吐泻，咳嗽痰多。
法半夏：具有治疗燥湿化痰、痰饮眩悸，风痰眩晕，痰厥头痛的功效。
胆南星：清火化痰，镇惊定痼。治中风痰迷，惊风癫痫，痰火喘嗽，头风眩晕。
茯苓：利水渗湿，健脾，宁心。用于水肿尿少，痰饮眩悸，脾虚食少，便溏泄泻，心神不安，惊悸失眠。
菖蒲：化痰，开窍，健脾，利湿。用于癫痫，惊悸健忘，神志不清，湿滞痞胀，泄泻痢疾，风湿疼痛，痈肿疥疮。
远志：具有安神益智、祛痰、消肿的功能，用于心肾不交引起的失眠多梦、健忘惊悸，神志恍惚，咳痰不爽，疮疡肿毒，乳房肿痛。
钩藤：清热平肝；熄风止痉。主治：小儿惊风；夜啼；热盛动风；子痫；肝阳眩晕；肝火头胀痛。
本发明治疗癫痫的中药组合物，选取14种天然中药科学配伍，配方简单，各原料药协同作用起到清心镇惊、清热解毒、安神助眠的效果，见效快，标本兼治，无毒副作用，而且其制备方法简单、服用方便，成本低。
具体实施方式
下面结合实施例对本发明内容作进一步的说明，但不是对本发明的限定。
实施例1
一种治疗癫痫的中药组合物，原料药的重量配比为：
决明子10g，紫石英5g，钩藤10g，茯苓10g，菖蒲6g，远志8g，栀子5g，法半夏5g，胆南星6g，柴胡8g，天麻10g，川贝5g，陈皮10g，大黄3g。
制备方法如下：按重量配比称取各原料，加入混合置于容器中，再加原料量重量8倍的水煎煮4次，每次用2倍的水煎煮40min，合并煎煮液，过滤去渣，滤液浓缩至50℃下相对密度为1.30g的浸膏，加入辅料，制成片剂，每片2g。
实施例2
一种治疗癫痫的中药组合物，原料药的重量配比为：
决明子12g，紫石英6g，钩藤12g，茯苓12g，菖蒲7g，远志10g，栀子6g，法半夏6g，胆南星7g，柴胡10g，天麻12g，川贝6g，陈皮11g，大黄4g。
制备方法如下：按重量配比称取各原料，加入混合置于容器中，再加原料量重量10倍的水煎煮4次，每次用2.5倍的水煎煮45min，合并煎煮液，过滤去渣，滤液浓缩至55℃下相对密度为1.30g的浸膏，加入辅料，制成片剂，每片3g。
实施例3
一种治疗癫痫的中药组合物，原料药的重量配比为：
决明子15g，紫石英7g，钩藤15g，茯苓15g，菖蒲8g，远志12g，栀子7g，法半夏7g，胆南星8g，柴胡12g，天麻15g，川贝7g，陈皮12g，大黄5g。
制备方法如下：按重量配比称取各原料，加入混合置于容器中，再加原料量重量12倍的水煎煮4次，每次用3倍的水煎煮50min，合并煎煮液，过滤去渣，滤液浓缩至60℃下相对密度为1.40g的浸膏，加入辅料，制成丸剂，每粒5g。
为了进一步证明本发明中药的临床疗效，选择收治患者中的90例，对本发明药物的疗效进行临床观察。年龄10-60岁，随机分为3组，每组为30例，分别为实验组1-3组。
实验组1-3组分别服用实施例1-3的药物，每日3次，每次内服3片／粒，9天为一个疗程，连续服用1-2个疗程。其中显效86例，有效88例，治愈84例，无效4例，治愈率93.3%，有效率97.8%。

Claims (3)

1.一种治疗癫痫的中药组合物，其特征是：由下述重量份配比的原料制成：
决明子10-15份，紫石英5-7份，钩藤10-15份，茯苓10-15份，菖蒲6-8份，远志8-12份，栀子5-7份，法半夏5-7份，胆南星6-8份，柴胡8-12份，天麻10-15份，川贝5-7份，陈皮10-12份，大黄3-5份。
2.根据权利要求1所述的治疗癫痫的中药组合物，其特征是：下述重量份配比的原料制成：
决明子12份，紫石英6份，钩藤12份，茯苓12份，菖蒲7份，远志10份，栀子6份，法半夏6份，胆南星7份，柴胡10份，天麻12份，川贝6份，陈皮11份，大黄4份。
3.根据权利要求1所述的治疗癫痫的中药组合物，其特征是：制备方法如下：按重量配比称取各原料，加入混合置于容器中，再加原料量重量8-12倍的水煎煮4次，每次用2-4倍的水煎煮40-50min，合并煎煮液，过滤去渣，滤液浓缩至50-60℃下相对密度为1.30-1.40g的浸膏，加入辅料，制成相应的剂型，即得。
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CN1179321A (zh) * 1997-10-28 1998-04-22 董国良 癫痫康复丸及其制备方法
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