CN105746546B - A kind of bactericidal composition of containing fluopicolide - Google Patents
A kind of bactericidal composition of containing fluopicolide Download PDFInfo
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- CN105746546B CN105746546B CN201610089047.9A CN201610089047A CN105746546B CN 105746546 B CN105746546 B CN 105746546B CN 201610089047 A CN201610089047 A CN 201610089047A CN 105746546 B CN105746546 B CN 105746546B
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- fluopicolide
- active
- disease
- bactericidal composition
- active constituent
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- 239000005782 Fluopicolide Substances 0.000 title claims abstract description 91
- GBOYJIHYACSLGN-UHFFFAOYSA-N fluopicolide Chemical compound ClC1=CC(C(F)(F)F)=CN=C1CNC(=O)C1=C(Cl)C=CC=C1Cl GBOYJIHYACSLGN-UHFFFAOYSA-N 0.000 title claims abstract description 91
- 239000000203 mixture Substances 0.000 title claims abstract description 47
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 20
- 239000000470 constituent Substances 0.000 claims abstract description 44
- 201000010099 disease Diseases 0.000 claims abstract description 43
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 43
- LDVVMCZRFWMZSG-OLQVQODUSA-N (3ar,7as)-2-(trichloromethylsulfanyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione Chemical compound C1C=CC[C@H]2C(=O)N(SC(Cl)(Cl)Cl)C(=O)[C@H]21 LDVVMCZRFWMZSG-OLQVQODUSA-N 0.000 claims abstract description 24
- 239000005745 Captan Substances 0.000 claims abstract description 24
- 229940117949 captan Drugs 0.000 claims abstract description 24
- 230000000694 effects Effects 0.000 claims abstract description 22
- 239000000375 suspending agent Substances 0.000 claims description 41
- 241000233679 Peronosporaceae Species 0.000 claims description 24
- 239000004563 wettable powder Substances 0.000 claims description 18
- 235000007164 Oryza sativa Nutrition 0.000 claims description 16
- 235000009566 rice Nutrition 0.000 claims description 16
- 239000003094 microcapsule Substances 0.000 claims description 13
- 239000003795 chemical substances by application Substances 0.000 claims description 11
- 239000000839 emulsion Substances 0.000 claims description 11
- 241000221785 Erysiphales Species 0.000 claims description 9
- 241000582441 Peronospora tabacina Species 0.000 claims description 9
- 206010039509 Scab Diseases 0.000 claims description 9
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 9
- 241001530056 Athelia rolfsii Species 0.000 claims description 8
- 239000011347 resin Substances 0.000 claims description 8
- 229920005989 resin Polymers 0.000 claims description 8
- 239000000725 suspension Substances 0.000 claims description 7
- 239000004530 micro-emulsion Substances 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 240000007594 Oryza sativa Species 0.000 claims 1
- 241000918585 Pythium aphanidermatum Species 0.000 claims 1
- 230000002195 synergetic effect Effects 0.000 abstract description 28
- 239000005797 Iprovalicarb Substances 0.000 abstract description 21
- NWUWYYSKZYIQAE-ZBFHGGJFSA-N L-(R)-iprovalicarb Chemical compound CC(C)OC(=O)N[C@@H](C(C)C)C(=O)N[C@H](C)C1=CC=C(C)C=C1 NWUWYYSKZYIQAE-ZBFHGGJFSA-N 0.000 abstract description 21
- OIPMQULDKWSNGX-UHFFFAOYSA-N bis[[ethoxy(oxo)phosphaniumyl]oxy]alumanyloxy-ethoxy-oxophosphanium Chemical compound [Al+3].CCO[P+]([O-])=O.CCO[P+]([O-])=O.CCO[P+]([O-])=O OIPMQULDKWSNGX-UHFFFAOYSA-N 0.000 abstract description 21
- XERJKGMBORTKEO-VZUCSPMQSA-N (1e)-2-(ethylcarbamoylamino)-n-methoxy-2-oxoethanimidoyl cyanide Chemical compound CCNC(=O)NC(=O)C(\C#N)=N\OC XERJKGMBORTKEO-VZUCSPMQSA-N 0.000 abstract description 20
- 239000005756 Cymoxanil Substances 0.000 abstract description 20
- 239000005754 Cyazofamid Substances 0.000 abstract description 19
- YXKMMRDKEKCERS-UHFFFAOYSA-N cyazofamid Chemical compound CN(C)S(=O)(=O)N1C(C#N)=NC(Cl)=C1C1=CC=C(C)C=C1 YXKMMRDKEKCERS-UHFFFAOYSA-N 0.000 abstract description 19
- 150000001875 compounds Chemical class 0.000 abstract description 12
- 230000000855 fungicidal effect Effects 0.000 abstract description 4
- 238000001228 spectrum Methods 0.000 abstract description 3
- 238000005406 washing Methods 0.000 abstract 1
- 238000013329 compounding Methods 0.000 description 30
- 239000003814 drug Substances 0.000 description 29
- 238000012360 testing method Methods 0.000 description 28
- 230000003449 preventive effect Effects 0.000 description 21
- 230000002265 prevention Effects 0.000 description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 17
- 241000209094 Oryza Species 0.000 description 15
- 239000000575 pesticide Substances 0.000 description 15
- 239000012071 phase Substances 0.000 description 15
- 239000002518 antifoaming agent Substances 0.000 description 14
- 239000002270 dispersing agent Substances 0.000 description 14
- 230000010165 autogamy Effects 0.000 description 12
- 239000003995 emulsifying agent Substances 0.000 description 10
- 239000008367 deionised water Substances 0.000 description 9
- 229910021641 deionized water Inorganic materials 0.000 description 9
- 238000002474 experimental method Methods 0.000 description 9
- 239000002904 solvent Substances 0.000 description 9
- 239000002562 thickening agent Substances 0.000 description 9
- 231100000820 toxicity test Toxicity 0.000 description 9
- 239000000080 wetting agent Substances 0.000 description 9
- 241000894006 Bacteria Species 0.000 description 8
- 241000233629 Phytophthora parasitica Species 0.000 description 8
- 230000002528 anti-freeze Effects 0.000 description 8
- 240000008067 Cucumis sativus Species 0.000 description 7
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 7
- 206010067482 No adverse event Diseases 0.000 description 6
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 description 6
- 150000001412 amines Chemical group 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 230000005764 inhibitory process Effects 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 241000233614 Phytophthora Species 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 5
- 238000013401 experimental design Methods 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 240000007124 Brassica oleracea Species 0.000 description 4
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 4
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 4
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 4
- 206010011732 Cyst Diseases 0.000 description 4
- 244000183278 Nephelium litchi Species 0.000 description 4
- 241000233622 Phytophthora infestans Species 0.000 description 4
- 208000031513 cyst Diseases 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 229920002521 macromolecule Polymers 0.000 description 4
- 239000003002 pH adjusting agent Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 241000198596 Alternaria tomatophila Species 0.000 description 3
- 241000207199 Citrus Species 0.000 description 3
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 3
- 241000233654 Oomycetes Species 0.000 description 3
- WHDHEVMINMZADQ-UHFFFAOYSA-N [F].N1C=CC=C1 Chemical compound [F].N1C=CC=C1 WHDHEVMINMZADQ-UHFFFAOYSA-N 0.000 description 3
- 230000008485 antagonism Effects 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 235000020971 citrus fruits Nutrition 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 229910052731 fluorine Inorganic materials 0.000 description 3
- 239000011737 fluorine Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 230000001018 virulence Effects 0.000 description 3
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- JHXVRRJXCDAINK-UHFFFAOYSA-N NC(=O)N.N#CC#N Chemical compound NC(=O)N.N#CC#N JHXVRRJXCDAINK-UHFFFAOYSA-N 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 238000000498 ball milling Methods 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 239000003610 charcoal Substances 0.000 description 2
- 230000006806 disease prevention Effects 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 230000002538 fungal effect Effects 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 241000219112 Cucumis Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 102100025287 Cytochrome b Human genes 0.000 description 1
- 108010075028 Cytochromes b Proteins 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000921313 Phyllopodium Species 0.000 description 1
- 241001503460 Plasmodiophorida Species 0.000 description 1
- 241000233639 Pythium Species 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 150000001408 amides Chemical group 0.000 description 1
- 239000007798 antifreeze agent Substances 0.000 description 1
- 150000003851 azoles Chemical class 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000002508 compound effect Effects 0.000 description 1
- 238000002242 deionisation method Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 230000002438 mitochondrial effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- RXJKFRMDXUJTEX-UHFFFAOYSA-N triethylphosphine Chemical group CCP(CC)CC RXJKFRMDXUJTEX-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
- A01N47/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing >N—S—C≡(Hal)3 groups
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of containing fluopicolide bactericidal composition, the bactericidal composition containing active components A Yu active constituent B, active components A is selected from fluopicolide, and active constituent B is selected from any one following compound：Cyazofamid, phosethyl-Al, cymoxanil, iprovalicarb, captan, and active components A and the weight ratio of active constituent B are 1: 80~60: 1.The present composition has the multiple diseases in various crop greater activity, and with apparent synergistic effect, expands fungicidal spectrum.And with the characteristics of dosage is small, resistance of rainwater washing against, and synergy is apparent.
Description
The application is divisional application, and original application is a kind of patent application " fluorine-containing pyrrole bacterium of Shaanxi Meibang Pesticide Co., Ltd.
The bactericidal composition of amine ", the application Wei ︰ 201210189064.1 of original application, original application day 2012.06.09.
Technical field
The invention belongs to technical field of pesticide, are related to a kind of bactericidal composition of containing fluopicolide answering in crop disease
With.
Technical background
Fluopicolide (fluopicolide) chemical name：Bis- chloro- N- of 2,6-【(the chloro- 5- trifluoromethyls -2- pyridyl groups of 3-)
Methyl】Benzamide, molecular formula：C14H8Cl3F3N2O.Fluopicolide is amides wide-spectrum bactericide, to Oomycete fungal germ
There is very high bioactivity, there is protection and therapeutic effect.Fluopicolide has stronger permeability.It can be from blade upper table downwards
Face is permeated, and is conducted from phyllopodium to blade tip direction.To that blade can be protected not infected by germ after young shoot processing.It can also be from root edge
Plant xylem is distributed to whole strain crop, but cannot be conducted along bast.
Cyazofamid (cyazofamid) molecular formula：C13H13ClN4O2S.The mechanism of action of cyazofamid is to block Oomycete germ
The electron transmission of internal mitochondrial cytochrome b c1 complexs carrys out the supply of interfering energy, and binding site is the Q1 centers of enzyme,
With other fungicide without cross tolerance.Its high selection activity to pathogen may be the sensitivity due to target enzymes to medicament
Caused by difference.To the rape knee of Oomycete fungal such as downy mildew, Pseudo peronospara, phytophthora, pythium spp and Plasmodiophoromycetes
Bacterium has very high bioactivity.
In the real process of agricultural production, controlling disease is easiest to generate the problem that the generation of disease drug resistance.No
It is compounded with kind ingredient, is to prevent the very common method of resistance disease.Heterogeneity is compounded, and is imitated according to practical application
Fruit, to judge that certain compounding is synergy, adduction or antagonism.In most cases, the compounding effect of pesticide is all to add
And effect, the compounding for really having synergistic effect is seldom, especially synergistic effect clearly, the very high compounding of synergy ratio just more
It is few.It studies, is found fluopicolide and cyazofamid, phosethyl-Al, cymoxanil, iprovalicarb, captan phase by inventor
Mutually compounding, there is a good synergistic effect in a certain range, and in relation to fluopicolide and cyazofamid, phosethyl-Al, cymoxanil,
Iprovalicarb, captan correlation compounding, at present at home and abroad there is not yet relevant report.
Invention content
There is synergistic function, the containing fluopicolide that use cost is low, preventive effect is good the purpose of the present invention is to propose to a kind of
Bactericidal composition.
The present invention is to be achieved through the following technical solutions：
A kind of bactericidal composition of containing fluopicolide, containing active components A and active constituent B, active components A and activity into
It is 1: 80~60: 1 to divide B weight ratios, and the active components A is selected from fluopicolide, and active constituent B is selected from cyazofamid, triethylphosphine
One kind in sour aluminium, cymoxanil, iprovalicarb, captan.The preferred weight ratio of active components A and active constituent B are 1 ︰, 60~40 ︰
1；More preferably the weight ratio of fluopicolide and cyazofamid is 1: 20~20: 1, the most preferably weight of fluopicolide and cyazofamid
Match is 1: 10~10: 1；More preferably the weight ratio of fluopicolide and phosethyl-Al is 1: 40~5: 1, most preferably fluorine pyrrole
The weight proportion of bacterium amine and phosethyl-Al is 1: 20~2: 1；More preferably the weight ratio of fluopicolide and cymoxanil is 1: 15
~5: 1；More preferably the weight ratio of fluopicolide and iprovalicarb is 1: 20~10: 1；More preferably fluopicolide and captan
Weight ratio is 1 ︰, 30~5 ︰ 1, and most preferably the weight proportion of fluopicolide and captan is 1: 20~3: 1.
The bactericidal composition of the containing fluopicolide can be made into wettable powder, water dispersible granules, suspending agent, water and milk
Agent, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent, microemulsion.
The bactericidal composition of the containing fluopicolide is used to prevent the disease of crop, and the crop makees including grain
Object, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit crop, hobby crop, tubers
Crop, oil crops, flower crop, medicinal crop, crop, green manure pasture crop.
The disease includes downy mildew, peronospora tabacina, epidemic disease, gray mold, powdery mildew, rice blast, banded sclerotial blight, black shin
Disease, leaf mold, resin disease, anthracnose, scab, ring spot, damping-off, rust.
The amount of application when content of active constituent depends on being used alone in the bactericidal composition of the present invention, also depends on one
Kind compound and another mixed ratio of compound and synergistic effect degree, at the same it is also related with target disease.Usual group
The weight percentage for closing active constituent in object is the 1%~90% of total weight, preferably 5%~80%.According to different
Preparation type, active component content range are different.In general, liquid preparation contains by weight 1%~60% active matter
Matter, preferably 5%~50%；Solid pharmaceutical preparation contains by weight 5%~80% active material, preferably 10%~
80%.
At least containing a kind of surfactant in the bactericidal composition of the present invention, so that active component is in water during application
Dispersion.Surface-active contents are the 2%~30% of total formulation weight, and surplus is solid or liquid diluent.
Surfactant selected by the bactericidal composition of the present invention is known in those skilled in the art：It can be selected from
One or more of dispersant, wetting agent, thickener or antifoaming agent.According to different dosage forms, this field can also be contained in preparation
Stabilizer, antifreeze well known to technical staff etc..
The bactericidal composition of invention can be used through dilution or directly before use by user.Its preparation can be by this field
Prepared by the processing method well known to technical staff, i.e., after active constituent is mixed with liquid flux or solid carrier, add table
Face activating agent such as one or more of dispersant, stabilizer, wetting agent, binding agent, antifoaming agent etc..
Comprising following component and content when wettable powder is made in composition：Active components A 0.5%~60%, activity into
Divide B 0.5%~80%, dispersant 1%~12%, wetting agent 1%~8%, filler surplus.
Composition includes following component and content when water dispersible granules are made：Active components A 0.5%~60%, activity into
Point B 0.5%~80%, dispersant 1%~12%, wetting agent 1%~8%, disintegrant 1%~10%, binding agent 0~8%,
Filler surplus.
Composition includes following component and content when suspending agent is made：Active components A 0.5%~50%, active constituent B
0.5%~50%, dispersant 1%~10%, wetting agent 1%~10%, antifoaming agent 0.01%~2%, thickener 0~2%, anti-
Freeze agent 0~8%, deionized water adds to 100%.
Composition includes following component and content when aqueous emulsion is made：Active components A 0.5%~50%, active constituent B
0.5%~50%, solvent 1%~20%, emulsifier 1%~12%, antifreeze 0~8%, antifoaming agent 0.01%~2%, thickening
Agent 0~2%, deionized water add to 100%.
Composition includes following component and content when suspension emulsion is made：Active components A 0.5%~50%, active constituent B
0.5%~50%, emulsifier 1%~10%, dispersant 1%~10%, solvent 1%~20%, antifoaming agent 0.01%~2%,
Thickener 0~2%, antifreeze 0~8%, deionized water add to 100%.
Composition includes following component and content when microcapsule suspending agent is made：Active components A 0.5%~50%, activity into
Divide B 0.5%~50%, macromolecule cyst material 1%~10%, dispersant 2%~10%, solvent 1%~10%, emulsifier
1%~7%, pH adjusting agent 0.01%~5%, antifoaming agent 0.01%~2%, deionized water add to 100%.
Composition includes following component and content when microcapsule suspension-suspendinagent agent is made：Active components A 0.5%~50% is lived
It is property ingredient B 0.5%~50%, macromolecule cyst material 1%~12%, dispersant 1%~12%, wetting agent 1%~8%, molten
Agent 1%~15%, emulsifier 1%~8%, antifoaming agent 0.01%~2%, thickener 0~2%, pH adjusting agent 0.01%~
5%th, deionized water adds to 100%.
Composition includes following component and content when microemulsion is made：Active components A 0.5%~50%, active constituent B
0.5%~50%, emulsifier 3%~25%, solvent 1%~10%, antifreeze 0~8%, antifoaming agent 0.01%~2%, go from
Sub- water adds to 100%.
The wettable powder the key technical indexes of the present invention：
The water dispersible granules the key technical indexes of the present invention：
The suspending agent the key technical indexes of the present invention：
The aqueous emulsion the key technical indexes of the present invention：
The suspension emulsion the key technical indexes of the present invention：
The microcapsule suspending agent the key technical indexes of the present invention：
The microcapsule suspension-suspendinagent agent the key technical indexes of the present invention：
The microemulsion the key technical indexes of the present invention：
The advantage of the invention is that：
(1) present composition has good synergy and lasting effect in a certain range, and preventive effect is higher than single dose；(2) agriculture
Medicinal dose is reduced, and is reduced residual quantity of the pesticide on crop, is mitigated environmental pollution；(3) fungicidal spectrum is expanded, to multiple diseases
Such as late blight, downy mildew, peronospora tabacina, epidemic disease, gray mold, powdery mildew, rice blast, banded sclerotial blight, balck shank, leaf mold, resin
Disease, anthracnose, scab, ring spot, damping-off, rust have greater activity.
Specific embodiment
With reference to embodiment to further instruction of the present invention, the percentage in embodiment is weight percentage, but
The present invention is not limited thereto.
Application Example one
1~12 wettable powder of example
Fluopicolide, active constituent B, dispersant, wetting agent, filler are mixed, are uniformly mixed in mixed cylinder, through air-flow
Pulverizer remixes uniformly after crushing, you can wettable powder product of the present invention is made.Specifically it is shown in Table 1,2.
1 example of table, 1~6 component and content
2 example of table, 7~12 each component and content
13~24 water dispersible granules of example
Fluopicolide, active constituent B, dispersant, wetting agent, disintegrant, filler etc. are needed together through air-flow crushing
The grain size wanted adds other auxiliary agents such as binding agent (can add can be not added with), obtains granulation materials.Item is quantified into feeding fluid bed
In granulating drier after granulation and drying, you can water dispersible granules product of the present invention is made, is specifically shown in Table 3,4.
3 example of table, 13~18 each component and content
4 example of table, 19~24 each component and content
25~36 suspending agent of example
By dispersant, wetting agent, antifoaming agent, thickener (can add can be not added with), antifreeze (can add can be not added with), by a high speed
Shear-mixed is uniform, adds in fluopicolide, active constituent B, ball milling 2~3 hours, make diameter of particle all in 5 μ in the ball mill
M is hereinafter, surplus is supplied with deionized water, you can suspending agent product of the present invention is made, is specifically shown in Table 5,6.
5 example of table, 25~30 each component and content
6 example of table, 31~36 each component and content
37~42 aqueous emulsion of example
Fluopicolide, active constituent B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase；By deionized water,
Antifreeze (can add can be not added with), thickener (can add can be not added with), antifoaming agent mix, into uniform water phase.In high-speed stirred
Under, water phase is added in into oil phase, aqueous emulsion product of the present invention is made.Specifically it is shown in Table 7.
7 example of table, 37~42 each component and content
43~47 suspension emulsion of example
Dispersant, antifoaming agent, thickener (can add can be not added with), antifreeze (can add can be not added with) warp will be added in fluopicolide
It is uniform to cross high speed shear-mixed, in the ball mill ball milling 2~3 hours, make diameter of particle all at 5 μm hereinafter, fluorine pyrrole bacterium is made
Then amine suspending agent directly emulsifies active constituent B, emulsifier, solvent and various auxiliary agents in suspending agent with high speed agitator,
Suspension emulsion product of the present invention is made.Specifically it is shown in Table 8.
8 example of table, 43~47 each component and content
Cyazofamid, phosethyl-Al, cymoxanil, iprovalicarb, captan in table 1~8 are exchanged, novel formulation can be made.
48~50 microcapsule suspending agent of example
Fluopicolide, active constituent B, macromolecule cyst material, solvent are mixed, makes to be dissolved into homogeneous oil phase, shear
Under the conditions of, by oil phase be added to containing emulsifier, pH adjusting agent, dispersant, antifoaming agent aqueous phase solution in, surplus deionization
Water is supplied, and two kinds of materials react in oil-water interfaces, forms high score ascus wall, and well dispersed micro- of the present composition is made
Capsule suspending agent product.Specifically it is shown in Table 9.
9 48~50 each components of table and content
51~55 microcapsule suspension-suspendinagent agent of example
Active constituent B, macromolecule cyst material, solvent are mixed, make to be dissolved into homogeneous oil phase, by oil phase in shearing condition
Under be added to containing emulsifier, pH adjusting agent aqueous phase solution in, well dispersed microcapsule suspending agent is made.By dispersant, wet
Profit agent, antifoaming agent, thickener (can add can be not added with) are uniformly mixed by high speed shear, add in fluopicolide, in the ball mill ball
Mill 2~3 hours makes diameter of particle all at 5 μm hereinafter, suspending agent is made, suspending agent then is added to micro-capsule suspension
Aqueous phase solution in, deionized water supplies surplus, and the well dispersed microcapsule suspension-suspendinagent agent product of the present composition is made.
Specifically it is shown in Table 10.
10 example of table, 51~55 each component and content
Cyazofamid, cymoxanil, iprovalicarb, captan in table are exchanged, novel formulation can be made.
56~61 microemulsion of example
Fluopicolide, active constituent B are dissolved in the homogenizer equipped with solvent, by emulsifier, antifreeze, (can add can not
Add), antifoaming agent, be added in the homogenizer equipped with above-mentioned solution, surplus give after being supplied with deionized water strongly mixing and it is even
Change, finally obtain the transparent microemulsion product of the present invention of clear appearance.Specifically it is shown in Table 11.
11 example of table, 56~61 each component and content
Cyazofamid, phosethyl-Al, cymoxanil, iprovalicarb, captan in table are exchanged, novel formulation can be made.
The embodiment of the present invention is the method being combined using Toxicity Determination and field trial.First pass through indoor virulence survey
It is fixed, clear and definite two kinds of medicaments compound by a certain percentage after synergy ratio (SR), SR ＜ 0.5 are antagonism, 0.5≤SR≤1.5
For summation action, SR ＞ 1.5 are synergistic effect, on this basis, then carry out field trial.
Test method：After prerun determines the effective inhibition concentration range of each medicament, medicament sets 5 respectively by active constituent content
A dosage processing, if clear water compares.Reference《Farm-chemical indoor determination test rule fungicide》It carries out, speed is grown using mycelia
Rate method measures virulence of the medicament to crop germ.Colony diameter is measured with crossing method after 72h, calculates the net growth of each processing
Amount, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter -5
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) is converted into logarithm (x), with minimum
Square law acquires virulence regression equation (y=a+bx), and thus calculates the EC of each medicament50Value.Simultaneously according to Wadley methods
Two medicament different ratio synergy ratios (SR) are calculated, SR ＜ 0.5 are antagonism, and 0.5≤SR≤1.5 are summation action,
SR ＞ 1.5 are synergistic effect.Calculation formula is as follows：
Wherein：A, b is respectively active components A and active constituent B ratio shared in combination；
A is fluopicolide；
B is selected from one of cyazofamid, phosethyl-Al, cymoxanil, iprovalicarb, captan kind.
Application Example two：
For trying disease：Cucumber downy mildew
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：Determine that the effectively inhibition of both fluopicolide and cyazofamid different ratio mixture is dense by pilot study
Spend range.
Toxicity test result
12 fluopicolide of table compounds the toxicity test analysis of results table to cucumber downy mildew with cyazofamid
As shown in Table 12, fluopicolide increases with the proportioning of cyazofamid compounding prevention cucumber downy mildew in 1 80~60 ︰ 1 of ︰
Effect ratio SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~60 ︰ 1 shows synergistic effect, fluopicolide and cyanogen
The proportioning of white azoles is 1: 20~20: 1, and synergistic effect is more prominent, and synergy ratio is more than 2.2；Fluopicolide and cyazofamid
Weight ratio is 1：Synergy ratio is maximum when 1, and synergistic effect is the most apparent.It is tested through applicant and finds fluopicolide and cyazofamid
Match for 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,
It is withered to downy mildew, peronospora tabacina, epidemic disease, gray mold, powdery mildew, rice blast, line when 1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20
The prevention of disease, balck shank, leaf mold, resin disease, anthracnose, scab, ring spot, damping-off, rust has apparent synergy
Effect, synergy ratio is more than 1.5.
Application Example three：
For trying disease：Rice blast
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：Fluopicolide and technical-grade fosetyl-aluminum and the two different ratio mixture are determined by pilot study
Effective inhibition concentration range
Toxicity test result
13 fluopicolide of table compounds the toxicity test analysis of results table to rice blast with phosethyl-Al
As shown in Table 13, fluopicolide prevents the proportioning of rice blast in 1 ︰, 80~60 ︰ 1 with phosethyl-Al compounding
When, synergy ratio SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~60 ︰ 1 shows synergistic effect, fluorine pyrrole bacterium
The proportioning of amine and phosethyl-Al is in 1 ︰ 40~5: 1, and synergistic effect is more prominent, and synergy ratio is more than 2.15；Fluorine pyrrole bacterium
Amine is 1 with phosethyl-Al weight ratio：Synergy ratio is maximum when 10, and synergistic effect is the most apparent.It is tested through applicant and finds fluorine
The proportioning of pyrrole bacterium amine and phosethyl-Al is 5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰
9th, 1 ︰ 10,1 ︰ 11,1 ︰ 12,1 ︰ 13,1 ︰ 14,1 ︰ 15,1 ︰ 16,1 ︰ 17,1 ︰ 18,1 ︰ 19,1 ︰ 20,1 ︰ 25,1 ︰ 30,1 ︰ 35,1 ︰ 40
When to downy mildew, peronospora tabacina, epidemic disease, gray mold, powdery mildew, rice blast, banded sclerotial blight, balck shank, leaf mold, resin disease, charcoal
The prevention of subcutaneous ulcer disease, scab, ring spot, damping-off, rust has apparent synergistic effect, and synergy ratio is more than 1.50.
Application Example four：
For trying disease：Early blight of tomato
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：The effective of fluopicolide and cymoxanil active compound and the two different ratio mixture is determined by pilot study
Inhibition concentration range.
Toxicity test result
14 fluopicolide of table compounds the toxicity test analysis of results table to early blight of tomato with cymoxanil
As shown in Table 14, fluopicolide increases with the proportioning of cymoxanil compounding prevention early blight of tomato in 1 80~60 ︰ 1 of ︰
Effect ratio SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~60 ︰ 1 shows synergistic effect, fluopicolide and frost
The proportioning of urea cyanogen is 1: 15~5: 1, and synergistic effect is more prominent, and synergy ratio is more than 2.15；Fluopicolide and cymoxanil
Weight ratio is 1：Synergy ratio is maximum when 3, and synergistic effect is the most apparent.It is tested through applicant and finds fluopicolide and cymoxanil
It matches as 5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 11,1 ︰ 12,1 ︰
13rd, to downy mildew, peronospora tabacina, epidemic disease, gray mold, powdery mildew, rice blast, banded sclerotial blight, balck shank, leaf mold when 1 ︰ 14,1 ︰ 15
The prevention of disease, resin disease, anthracnose, scab, ring spot, damping-off, rust has apparent synergistic effect, and synergy ratio is equal
More than 1.50.
Application Example five：
For trying disease：Downy mildew of garpe
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：The effective of fluopicolide and iprovalicarb active compound and the two different ratio mixture is determined by pilot study
Inhibition concentration range.
Toxicity test result
15 fluopicolide of table compounds the toxicity test analysis of results table to downy mildew of garpe with iprovalicarb
As shown in Table 15, fluopicolide increases with the proportioning of iprovalicarb compounding prevention downy mildew of garpe in 1 80~60 ︰ 1 of ︰
Effect ratio SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~60 ︰ 1 shows synergistic effect, fluopicolide and figured silk fabrics
The proportioning of mould prestige is 1: 20~10: 1, and synergistic effect is more prominent, and synergy ratio is more than 2.10；Fluopicolide and iprovalicarb
Weight ratio is 1：Synergy ratio is maximum when 2, and synergistic effect is the most apparent.It is tested through applicant and finds fluopicolide and iprovalicarb
It matches as 10 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20
When to downy mildew, peronospora tabacina, epidemic disease, gray mold, powdery mildew, rice blast, banded sclerotial blight, balck shank, leaf mold, resin disease, charcoal
The prevention of subcutaneous ulcer disease, scab, ring spot, damping-off, rust has apparent synergistic effect, and synergy ratio is more than 1.50.
Application Example six：
For trying disease：Citrus anthracnose
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：The effective of fluopicolide and captan active compound and the two different ratio mixture is determined by pilot study
Inhibition concentration range.
16 fluopicolide of table compounds the toxicity test analysis of results table to citrus anthracnose with captan
As shown in Table 16, fluopicolide increases with the proportioning of captan compounding prevention citrus anthracnose in 1 80~60 ︰ 1 of ︰
Effect ratio SR is all higher than 1.5, both illustrates that in the range of 1 ︰, 80~60 ︰ 1 mixture shows synergistic effect, fluopicolide with gram
The proportioning of bacterium pellet is 1: 30~5: 1, and synergistic effect is more prominent, and synergy ratio is more than 2.10；Fluopicolide and captan
Weight ratio is 1：Synergy ratio is maximum when 6, and synergistic effect is the most apparent.It is tested through applicant and finds fluopicolide and captan
It matches as 5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20,1 ︰
25th, to downy mildew, peronospora tabacina, epidemic disease, gray mold, powdery mildew, rice blast, banded sclerotial blight, balck shank, leaf mold, tree during 1 ︰ 30
The prevention of fat disease, anthracnose, scab, ring spot, damping-off, rust has apparent synergistic effect, and synergy ratio exists
More than 1.50.
Seven fluopicolide of Application Example and active constituent B and its compounding prevention cucumber downy mildew test of pesticide effectiveness
This experiment is arranged in Shaanxi Province Jingyang County, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, control
10% fluopicolide suspending agent (autogamy), 100g/L cyazofamids suspending agent (purchased in market), 40% phosethyl-Al wettable powder (city
Purchase), 20% cymoxanil suspending agent (purchased in market), 10% iprovalicarb suspending agent (autogamy), 50% captan wettable powder (purchased in market).
The cucumber downy mildew state of an illness is investigated before medicine, in state of an illness first time at initial stage dispenser, every dispenser in 7 days is primary, altogether dispenser 2 times.
3 days after second of dispenser, disease index is investigated respectively and calculates preventive effect within 7 days, 15 days.Experimental result is as follows：
17 fluopicolide of table and active constituent B and its compounding prevention cucumber downy mildew test of pesticide effectiveness
As can be seen from Table 17, cucumber downy mildew can be effectively prevented after fluopicolide and active constituent B and its compounding, prevented
Effect is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
Eight fluopicolide of Application Example and active constituent B and its compounding prevention late blight of potato test of pesticide effectiveness
This test arrangement in Shaanxi Province's Weinan City, by Shaanxi Meibang Pesticide Co., Ltd. researched and developed, provided by test medicine, control
10% fluopicolide suspending agent (autogamy), 100g/L cyazofamids suspending agent (purchased in market), 40% phosethyl-Al wettable powder (city
Purchase), 20% cymoxanil suspending agent (purchased in market), 10% iprovalicarb suspending agent (autogamy), 50% captan wettable powder (purchased in market).
The late blight of potato state of an illness is investigated before medicine, in state of an illness first time at initial stage dispenser, every dispenser in 7 days is primary, dispenser 2 altogether
It is secondary.7 days after second of dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.Experimental result is as follows：
18 fluopicolide of table and active constituent B and its compounding prevention late blight of potato test of pesticide effectiveness
As can be seen from Table 18, the late blight of potato can be effectively prevented after fluopicolide and active constituent B and its compounding, prevented
The preventive effect that effect is superior to single dose is controlled, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
Nine fluopicolide of Application Example and active constituent B and its compounding prevention cabbage downy mildew test of pesticide effectiveness
This test arrangement in Xian District, Shanxi Province suburban area, by Shaanxi Meibang Pesticide Co., Ltd. researched and developed, provided by test medicine,
Compare 10% fluopicolide suspending agent (autogamy), 100g/L cyazofamids suspending agent (purchased in market), 40% phosethyl-Al wettable powder
Agent (purchased in market), 20% cymoxanil suspending agent (purchased in market), 10% iprovalicarb suspending agent (autogamy), 50% captan wettable powder
(purchased in market).
The cabbage downy mildew state of an illness is investigated before medicine, in state of an illness first time at initial stage dispenser, every dispenser in 7 days is primary, altogether dispenser 2 times.
7 days after second of dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.Experimental result is as follows：
19 fluopicolide of table and active constituent B and its compounding prevention cabbage downy mildew test of pesticide effectiveness
As can be seen from Table 19, cabbage downy mildew can be effectively prevented after fluopicolide and active constituent B and its compounding, prevented
Effect is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
Ten fluopicolide of Application Example and active constituent B and its compounding prevention peronophythora litchi test of pesticide effectiveness
This test arrangement in Dongguan City, Guangdong Province, by Shaanxi Meibang Pesticide Co., Ltd. researched and developed, provided by test medicine, control
10% fluopicolide suspending agent (autogamy), 100g/L cyazofamids suspending agent (purchased in market), 40% phosethyl-Al wettable powder (city
Purchase), 20% cymoxanil suspending agent (purchased in market), 10% iprovalicarb suspending agent (autogamy), 50% captan wettable powder (purchased in market).
The peronophythora litchi state of an illness is investigated, in state of an illness first time at initial stage dispenser, every dispenser in 7 days is primary, altogether dispenser 2 times.The
7 days after secondary dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.Experimental result is as follows：
20 fluopicolide of table and active constituent B and its compounding prevention peronophythora litchi test of pesticide effectiveness
As can be seen from Table 20, peronophythora litchi can be effectively prevented after fluopicolide and active constituent B and its compounding, prevented
The preventive effect that effect is superior to single dose is controlled, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
11 fluopicolide of Application Example and active constituent B and its compounding prevention apple anthracnose test of pesticide effectiveness
This experiment is arranged in Shaanxi Province's Weinan City, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, control
10% fluopicolide suspending agent (autogamy), 100g/L cyazofamids suspending agent (purchased in market), 40% phosethyl-Al wettable powder (city
Purchase), 20% cymoxanil suspending agent (purchased in market), 10% iprovalicarb suspending agent (autogamy), 50% captan wettable powder (purchased in market).
The apple anthracnose state of an illness is investigated before medicine, in state of an illness first time at initial stage dispenser, every dispenser in 7 days is primary, altogether dispenser 2 times.
7 days after second of dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.Experimental result is as follows：
21 fluopicolide of table and active constituent B and its compounding prevention apple anthracnose test of pesticide effectiveness
As can be seen from Table 21, apple anthracnose can be effectively prevented after fluopicolide and active constituent B and its compounding, prevented
Effect is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
12 fluopicolide of Application Example and active constituent B and its compounding prevention rice blast test of pesticide effectiveness
This test arrangement in Shaanxi Province's Hanzhong City, by Shaanxi Meibang Pesticide Co., Ltd. researched and developed, provided by test medicine, control
10% fluopicolide suspending agent (autogamy), 100g/L cyazofamids suspending agent (purchased in market), 40% phosethyl-Al wettable powder (city
Purchase), 20% cymoxanil suspending agent (purchased in market), 10% iprovalicarb suspending agent (autogamy), 50% captan wettable powder (purchased in market).
The rice blast state of an illness is investigated before medicine, in state of an illness first time at initial stage dispenser, every dispenser in 7 days is primary, altogether dispenser 2 times.
7 days after second of dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.Experimental result is as follows：
22 fluopicolide of table and active constituent B and its compounding prevention rice blast test of pesticide effectiveness
As can be seen from Table 22, rice blast can be effectively prevented after fluopicolide and active constituent B and its compounding, prevented
Effect is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
The experiment by different places throughout the country obtains afterwards, fluopicolide and cyazofamid, phosethyl-Al, white urea
Cyanogen, iprovalicarb, captan compounding after in various crop downy mildew, peronospora tabacina, epidemic disease, gray mold, powdery mildew, rice blast
The Common Diseases such as disease, banded sclerotial blight, balck shank, leaf mold, resin disease, anthracnose, scab, ring spot, damping-off, rust are prevented
Effect is 95% on excellent, in single dose preventive effect, synergistic effect is apparent.
Claims (6)
1. a kind of bactericidal composition of containing fluopicolide, it is characterised in that：Effective active composition is active components A and active constituent
B, active components A and active constituent B weight ratios are 1: 80~60: 1, and the active components A is fluopicolide, active constituent B
For captan.
2. the bactericidal composition of containing fluopicolide according to claim 1, it is characterised in that：Active components A with activity into
The weight ratio for dividing B is 1: 60~40: 1.
3. the bactericidal composition of containing fluopicolide according to claim 2, it is characterised in that：
The weight ratio of fluopicolide and captan is 1 ︰, 30~5 ︰ 1.
4. the bactericidal composition of the containing fluopicolide according to any one in claims 1 to 3, it is characterised in that：Combination
Object be made wettable powder, water dispersible granules, suspending agent, aqueous emulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent,
Microemulsion.
5. the bactericidal composition of containing fluopicolide according to claim 4 is used to prevent the purposes of crop disease.
6. purposes according to claim 5, it is characterised in that：The disease include downy mildew, peronospora tabacina, epidemic disease,
Gray mold, powdery mildew, rice blast, banded sclerotial blight, balck shank, leaf mold, resin disease, anthracnose, scab, ring spot, damping-off,
Rust.
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| WO2010118946A2 (en) * | 2009-04-15 | 2010-10-21 | Syngenta Participations Ag | Fungicidal mixtures |
| EP2664238A1 (en) * | 2011-01-14 | 2013-11-20 | SDS Biotech K. K. | 4-(3-butynyl)aminopyrimidine derivative-containing pest control composition for agricultural or horticultural use |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1132816C (en) * | 1998-02-19 | 2003-12-31 | 阿方蒂农科英国有限公司 | 2-pyridylmethylamine derivatives useful as fungicides |
| WO2010118946A2 (en) * | 2009-04-15 | 2010-10-21 | Syngenta Participations Ag | Fungicidal mixtures |
| EP2664238A1 (en) * | 2011-01-14 | 2013-11-20 | SDS Biotech K. K. | 4-(3-butynyl)aminopyrimidine derivative-containing pest control composition for agricultural or horticultural use |
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|---|---|
| CN105746546A (en) | 2016-07-13 |
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Address after: 715500 Pucheng high tech Industrial Development Zone, Weinan, Shaanxi Patentee after: SHAANXI MEIBANG PHARMACEUTICAL GROUP Co.,Ltd. Address before: 715500 Shaanxi Pucheng Weinan County agricultural base industrial park Patentee before: Shaanxi Meibang pesticide Co.,Ltd. |
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