CN105726803A - 一种治疗猩红热的药物组合物及制作方法 - Google Patents

一种治疗猩红热的药物组合物及制作方法 Download PDF

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CN105726803A
CN105726803A CN201610116718.6A CN201610116718A CN105726803A CN 105726803 A CN105726803 A CN 105726803A CN 201610116718 A CN201610116718 A CN 201610116718A CN 105726803 A CN105726803 A CN 105726803A
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于海波
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Abstract

本发明涉及一种治疗的中药组合物，其特征在于原料药的重量份数如下：儿茶2～4份、桑白皮4～6份、煅石膏6～9份、生地黄6～9份、苦参4～6份、墨旱莲6～9份、竹节参6～9份、灯心草6～9份、布渣叶6～9份、皂角刺4～6份、紫珠叶6～8份、茯苓6～9份。本发明中药的有益效果是：清热凉血、除湿止痒、宣肺祛斑、利水渗湿，健脾，宁心。对急慢性斑疹性疾病均有效。

Description

一种治疗猩红热的药物组合物及制作方法
技术领域
本发明涉及一种治疗猩红热的药物组合物及制作方法。
背景技术
众所周知，众所周知，猩红热：为A群溶血性链球菌感染引起的急性呼吸道传染病。其临床特征为发热、咽峡炎、全身弥漫性鲜红色皮疹和疹退后明显的脱屑。少数患者患病后由于变态反应而出现心、肾、关节的损害。本病一年四季都有发生，尤以冬春之季发病为多。见于小儿，尤以5-15岁居多。中医认为：痧毒疫疠之邪侵犯肺卫，肺胃受邪，其气失和，邪入营血可进一步加重病情。猩红热发病后西医方面往往采取对症治疗，不能达到标本兼治的效果。
发明内容
本发明所要解决的技术问题是为了克服技术上的不足，提供一种疗效好、疗程短、治愈率高，且无毒副作用的一种治疗猩红热的药物组合物。
本发明中药的有益效果是：清热凉血、除湿止痒、宣肺祛斑、利水渗湿，健脾，宁心。对急慢性斑疹性疾病均有效。
为实现以上目的，一种治疗猩红热的药物组合物，其特征在于原料药的重量份数如下：儿茶2～4份、桑白皮4～6份、煅石膏6～9份、生地黄6～9份、苦参4～6份、墨旱莲6～9份、竹节参6～9份、灯心草6～9份、布渣叶6～9份、皂角刺4～6份、紫珠叶6～8份、茯苓6～9份。
制作方法：将儿茶蒸馏提取蒸馏液备用；取净生石膏，照明煅法(附录IID)煅至酥松；将桑白皮、煅石膏、生地黄、墨旱莲、苦参、竹节参、灯心草、布渣叶、皂角刺、紫珠叶、茯苓加入70％乙醇的多功能提取罐中，加热回流30分钟，滤液滤过，回收乙醇至尽；再将上述残渣加水煎煮2次，每次1小时，合并2次滤液，再与上述蒸馏液、醇提液合并按1∶0.5加入糊精，浓缩至相对密度为1.15～1.28(50℃)的清膏，即得。
本发明中药中的儿茶味苦、涩，性微寒。归肺、心经。功效：活血止痛，止血生肌，收湿敛疮，清肺化痰。用于疮疡不敛，湿疹、湿疮，肺热咳嗽......。桑白皮本品为桑科植物桑MorusalbaL.的干燥根皮。性味与归经：甘，寒。归肺经。功能与主治：泻肺平喘，利水消肿。用于肺热喘咳，水肿胀满尿少，面目肌肤浮肿。具有抗炎作用桑白皮水提取物给大鼠口服或注射对角叉菜胶及葡聚糖所引起的脚肿胀有抑制作用。抗菌作用桑白皮煎剂对金黄色葡萄球菌有较强的抑制作用；对伤寒杆菌及福氏痢疾杆菌也有轻度的抑制作用。桑皮呋喃A对金黄色葡萄球菌、分歧杆菌均有较强的抑菌活性。环桑皮素也有抗真菌作用。煅石膏味甘、辛、涩，性寒。归肺、胃经。功效：收湿，生肌，敛疮，止血。用于温病高热，身发斑疹。生地黄味甘、苦，性寒。归心、肝、肾经。功效：清热生津，凉血，止血。用于热病伤阴，舌绛烦渴，温毒发斑，吐血衄血，咽喉肿痛。苦参味苦，性寒。归心、肝、胃、大肠、膀胱经。功效：清热燥湿，利尿，杀虫，宁心止悸。用于湿热泻痢，便血，黄疸尿赤，淋证涩痛，小便不利，赤白带下，阴肿阴痒，湿疹湿疮，皮肤瘙痒，疥癣麻风，心悸不宁。墨旱莲味甘、酸，性寒。归肾、肝经。功效：滋补肝肾，凉血止血。用于肝肾阴虚，牙齿松动，须发早白，眩晕耳鸣，腰膝酸软，阴虚血热吐血，衄血，尿血，血痢，崩漏下血，外伤出血。竹节参味甘、微苦，性温。归肝、脾、肺经。功效：滋补强壮，散瘀止痛，止血祛痰。用于病后虚弱，劳嗽咯血，咳嗽痰多，跌扑损伤。紫珠叶味苦、涩，性凉。归肝、肺、胃经。功效：凉血收敛止血，散瘀解毒消肿。用于衄血，咯血，吐血，便血，崩漏，外伤出血，热毒疮疡，水火烫伤。灯心草味甘、淡，性微寒。归心、肺、小肠经。功效：清心火，利小便。用于心烦失眠，尿少涩痛，口舌生疮。布渣叶味酸，性凉。归脾、胃经。功效：消食化滞，清热利湿。用于饮食积滞，感冒发热，湿热黄疸等。皂角刺味辛，性温。归肝、胃经。功效：消肿托毒，排脓，杀虫。茯苓味甘、淡，性平。归心、肺、脾、肾经。功效：利水渗湿，健脾，宁心。用于水肿尿少，痰饮眩悸，脾虚食少，便溏泄泻，心神不安，惊悸失眠。以上药物搭配，治疗该病，相得益彰。
本发明遵循中医的处方用药原则，经过多年临床应用验证，有效率为90％以上，治愈率85％以上。
具体实施方式
下面结合实施病例对本发明作进一步描述：
实施例1：一种治疗猩红热的药物组合物，其特征在于原料药的重量份数如下：儿茶2～4份、桑白皮4～6份、煅石膏6～9份、生地黄6～9份、苦参4～6份、墨旱莲6～9份、竹节参6～9份、灯心草6～9份、布渣叶6～9份、皂角刺4～6份、紫珠叶6～8份、茯苓6～9份。
制作方法同上述。
实施例2：一种治疗猩红热的药物组合物，其特征在于原料药的重量份数如下：儿茶4份、桑白皮4份、石膏9份、生地黄6份、苦参6份、墨旱莲6份、竹节参9份、灯心草6份、布渣叶6份、皂角刺4份、紫珠叶8份、茯苓9份。制作方法同实施例1，即得清膏，分装成每袋10g。
临床疗效总结
一、一般资料：本发明的中药，多年来临床上应用，治疗病人上百例效果频佳。
二、诊断标准：1.接触史：有与猩红热或咽峡炎患者接触史者，有助于诊断。2.临床表现：骤起发热、咽峡炎、典型的皮疹、口周苍白、杨梅舌、帕氏线、恢复期脱皮等，为猩红热的特点。3.实验室检查：白细胞数增高，嗜中性粒细胞占80％以上。红疹毒素试验早期为阳性。咽试子、脓液培养可获得A组链球菌。
三、服药方法：每日2次，成人每次10g；儿童7-12岁减半；3-7岁1/3份；幼儿1/4份早晚各服1次。10日为一疗程。
四、疗效判断标准：
治愈：临床症状完全消失。
好转：临床症状好转。
无效：病情未见好转或加重。
五、治疗效果：多年临床应用，经统计有效率100％，治愈率90％以上。
六、典型病例：
1、孙X，女，15岁。学生。2013年春天就诊，患者和母亲叙述，1周前出现咽痛，昨晚开始发热、全身弥漫性鲜红色皮疹，经用青霉素、退热片，症状改善不明显，皮疹逐步增加。实验室检查：白细胞增高。家长要求内服本发明中药1疗程，皮疹消退，血象恢复正常，至今未再复发。
2、姜XX，男，12岁，学生。2014年6月就诊。主诉发热、咽痛、扁桃体炎，服罗红霉素服药3天，不见好转并出现咽峡炎、典型的皮疹、口周苍白、杨梅舌。实验室：白细胞和中性细胞增高；咽拭子培养为A组乙型溶血性链球菌。家长要求内服本发明中药2疗程，皮疹消退，血象恢复正常，至今未再复发。
3、李X，女，6岁，幼儿班。2014年7月就诊，患者家属主诉精神不振2天，发热、全身弥漫性鲜红色皮疹2天。家长要求内服本发明中药1疗程，皮疹消退，血象恢复正常，至今未再复发。

Claims (2)

1.一种治疗猩红热的药物组合物，其特征在于原料药的重量份数如下：儿茶2～4份、桑白皮4～6份、煅石膏6～9份、生地黄6～9份、苦参4～6份、墨旱莲6～9份、竹节参6～9份、灯心草6～9份、布渣叶6～9份、皂角刺4～6份、紫珠叶6～8份、茯苓6～9份。
2.根据权利要求1一种治疗猩红热的药物组合物的制作方法：其特征是先将儿茶蒸馏提取蒸馏液备用；取净生石膏，照明煅法(附录IID)煅至酥松；将桑白皮、煅石膏、生地黄、墨旱莲、苦参、竹节参、灯心草、布渣叶、皂角刺、紫珠叶、茯苓加入70％乙醇的多功能提取罐中，加热回流30分钟，滤液滤过，回收乙醇至尽；再将上述残渣加水煎煮2次，每次1小时，合并2次滤液，再与上述蒸馏液、醇提液合并按1∶0.5加入糊精，浓缩至相对密度为1.15～1.28(50℃)的清膏，即得。
CN201610116718.6A 2016-02-21 2016-02-21 一种治疗猩红热的药物组合物及制作方法 Withdrawn CN105726803A (zh)

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