CN105722524B - 用于重组人分泌球蛋白的改进方法 - Google Patents
用于重组人分泌球蛋白的改进方法 Download PDFInfo
- Publication number
- CN105722524B CN105722524B CN201480015596.0A CN201480015596A CN105722524B CN 105722524 B CN105722524 B CN 105722524B CN 201480015596 A CN201480015596 A CN 201480015596A CN 105722524 B CN105722524 B CN 105722524B
- Authority
- CN
- China
- Prior art keywords
- respiratory
- rhscgb3a2
- scgb3a2
- further object
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Marine Sciences & Fisheries (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/843,289 | 2013-03-15 | ||
| US13/843,289 US20140274915A1 (en) | 2013-03-15 | 2013-03-15 | Methods of Use for Recombinant Human Secretoglobins |
| PCT/US2014/030101 WO2014145357A2 (en) | 2013-03-15 | 2014-03-16 | Improved methods of use for recombinant human secretoglobins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105722524A CN105722524A (zh) | 2016-06-29 |
| CN105722524B true CN105722524B (zh) | 2020-02-21 |
Family
ID=51529893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480015596.0A Expired - Fee Related CN105722524B (zh) | 2013-03-15 | 2014-03-16 | 用于重组人分泌球蛋白的改进方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US20140274915A1 (enExample) |
| EP (1) | EP2968464B1 (enExample) |
| JP (1) | JP6513632B2 (enExample) |
| KR (1) | KR20160011621A (enExample) |
| CN (1) | CN105722524B (enExample) |
| AU (1) | AU2014233116A1 (enExample) |
| BR (1) | BR112015021265A2 (enExample) |
| CA (1) | CA2907395A1 (enExample) |
| ES (1) | ES2883933T3 (enExample) |
| IL (1) | IL241418A0 (enExample) |
| MX (1) | MX2015013091A (enExample) |
| RU (1) | RU2662665C2 (enExample) |
| SG (1) | SG11201507276UA (enExample) |
| UA (1) | UA118756C2 (enExample) |
| WO (1) | WO2014145357A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140274915A1 (en) * | 2013-03-15 | 2014-09-18 | Clarassance, Inc. | Methods of Use for Recombinant Human Secretoglobins |
| WO2016205430A1 (en) * | 2015-06-15 | 2016-12-22 | Therabron Therapeutics, Inc. | Recombinant human cc10 protein facilitates repair and protects against damage to the respiratory epithelium due to exposure to both cigarette and other smoke |
| WO2018178051A1 (en) * | 2017-03-28 | 2018-10-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Scgb1a1 polymorphism for the prediction and therapy or prevention of primary graft dysfunction |
| WO2019143934A1 (en) | 2018-01-19 | 2019-07-25 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-cancer activity of scbg3a2 and lps |
| AU2019387570A1 (en) * | 2018-11-30 | 2021-07-15 | Apc Research Assets Llc | Compositions and methods of use for secretoglobins to protect the glycocalyx via interactions with heparan sulfate proteoglycan proteins |
| KR20200138684A (ko) * | 2020-11-17 | 2020-12-10 | 김유신 | 토양 파쇄기를 장착한 친환경 고온스팀 토양소독기 |
| WO2023212398A1 (en) * | 2022-04-29 | 2023-11-02 | Apc Research Assets Llc | Secretoglobins for suppression of antibody responses |
| CN119631983B (zh) * | 2024-12-30 | 2025-07-22 | 西南医科大学 | 一种心脏原发性肿瘤小鼠模型的构建方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040047857A1 (en) | 1997-05-28 | 2004-03-11 | Pilon Aprile L. | Methods and compositions for the treatment of fibrotic conditions & impaired lung function & to enhance lymphocyte production |
| US20030008816A1 (en) | 1997-05-28 | 2003-01-09 | Pilon Aprile L. | Methods and compositions for the treatment of fibrotic conditions & impaired lung function & to enhance lymphocyte production |
| US20060281681A1 (en) * | 1997-05-28 | 2006-12-14 | Pilon Aprile L | Methods and compositions for the reduction of neutrophil influx and for the treatment of bronchpulmonary dysplasia, respiratory distress syndrome, chronic lung disease, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease |
| AU5551299A (en) | 1998-08-13 | 2000-03-06 | Trustees Of The University Of Pennsylvania, The | Method of identifying proteins |
| US6953666B1 (en) | 1998-11-06 | 2005-10-11 | Emory University | Biomarkers for oxidative stress |
| WO2004101824A1 (ja) * | 2003-05-14 | 2004-11-25 | Shionogi & Co., Ltd. | 慢性閉塞性肺疾患の検出方法 |
| US7655413B2 (en) * | 2003-06-26 | 2010-02-02 | Lifesensors, Inc. | Methods and compositions for enhanced protein expression and purification |
| KR20060111508A (ko) | 2003-11-14 | 2006-10-27 | 알자 코포레이션 | 조사된 부형제 약물 제형에서 약물 산화 최소화 |
| US20060275794A1 (en) * | 2005-03-07 | 2006-12-07 | Invitrogen Corporation | Collections of matched biological reagents and methods for identifying matched reagents |
| JP2007059191A (ja) | 2005-08-24 | 2007-03-08 | Kazuo Kono | 照明器具駆動回路 |
| WO2008039941A2 (en) * | 2006-09-27 | 2008-04-03 | The Government Of The Usa As Represented By The Secretary Of The Dpt. Of Health And Human Services | Scgb3a2 as a growth factor and anti-apoptotic agent |
| US20090004684A1 (en) | 2007-05-23 | 2009-01-01 | Claudia Susanne Maier | Compositions and Methods for Detection and Quantification of Protein Oxidation |
| DK2488205T3 (en) | 2009-10-15 | 2017-01-16 | Therabron Therapeutics Inc | Recombinant human CC10 protein for the treatment of influenza |
| RU2439569C1 (ru) * | 2010-11-12 | 2012-01-10 | Федеральное государственное учреждение "Ивановский научно-исследовательский институт материнства и детства имени В.Н. Городкова" Министерства здравоохранения и социального развития Российской Федерации | Способ прогнозирования бронхолегочной дисплазии у детей с врожденной пневмонией |
| US20140274915A1 (en) | 2013-03-15 | 2014-09-18 | Clarassance, Inc. | Methods of Use for Recombinant Human Secretoglobins |
-
2013
- 2013-03-15 US US13/843,289 patent/US20140274915A1/en not_active Abandoned
-
2014
- 2014-03-16 CN CN201480015596.0A patent/CN105722524B/zh not_active Expired - Fee Related
- 2014-03-16 RU RU2015144359A patent/RU2662665C2/ru active
- 2014-03-16 JP JP2016503332A patent/JP6513632B2/ja active Active
- 2014-03-16 MX MX2015013091A patent/MX2015013091A/es active IP Right Grant
- 2014-03-16 UA UAA201509797A patent/UA118756C2/uk unknown
- 2014-03-16 BR BR112015021265A patent/BR112015021265A2/pt not_active IP Right Cessation
- 2014-03-16 KR KR1020157029167A patent/KR20160011621A/ko not_active Ceased
- 2014-03-16 WO PCT/US2014/030101 patent/WO2014145357A2/en not_active Ceased
- 2014-03-16 SG SG11201507276UA patent/SG11201507276UA/en unknown
- 2014-03-16 EP EP14763146.9A patent/EP2968464B1/en active Active
- 2014-03-16 AU AU2014233116A patent/AU2014233116A1/en not_active Abandoned
- 2014-03-16 ES ES14763146T patent/ES2883933T3/es active Active
- 2014-03-16 CA CA2907395A patent/CA2907395A1/en not_active Abandoned
-
2015
- 2015-09-09 IL IL241418A patent/IL241418A0/en unknown
- 2015-10-12 US US14/880,908 patent/US9765127B2/en active Active
-
2017
- 2017-09-18 US US15/707,934 patent/US10556938B2/en active Active
-
2020
- 2020-02-07 US US16/785,221 patent/US11512121B2/en active Active
-
2022
- 2022-11-28 US US18/070,407 patent/US20240376162A1/en not_active Abandoned
Non-Patent Citations (5)
| Title |
|---|
| An update on pharmacologic approaches to bronchopulmonary dysplasia;Sailaja等;《SciVerse ScienceDirect》;20130401;第37卷;第115-123页 * |
| CC10 蛋白功能及在疾病中的作用研究进展;魏颖等;《中国医药生物技术》;20111031;第6卷(第5期);第359-363页 * |
| Intratracheal Clara cell secretory protein (CCSP) administration in preterm infants with or at risk of respiratory distress syndrome (Protocol);Mohamed等;《John Wiley & Sons, Ltd》;20110511(第1期);第1-9页 * |
| Preclinical evaluation of human secretoglobin 3A2 in mouse models of lung development and fibrosis;Cai等;《AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY》;20140131;第306卷(第1期);第L10-L22页 * |
| Safety, pharmacokinetics, and anti-inflammatory effects of intratracheal recombinant human Clara cell protein in premature infants with respiratory distress syndrome;Levine等;《PEDIATRIC RESEARCH》;20050731;第58卷(第1期);第15-21页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2014233116A1 (en) | 2015-09-24 |
| US9765127B2 (en) | 2017-09-19 |
| UA118756C2 (uk) | 2019-03-11 |
| US20180244735A1 (en) | 2018-08-30 |
| MX2015013091A (es) | 2016-10-07 |
| US20200262878A1 (en) | 2020-08-20 |
| US20240376162A1 (en) | 2024-11-14 |
| US11512121B2 (en) | 2022-11-29 |
| EP2968464A2 (en) | 2016-01-20 |
| CA2907395A1 (en) | 2014-09-18 |
| KR20160011621A (ko) | 2016-02-01 |
| RU2662665C2 (ru) | 2018-07-26 |
| CN105722524A (zh) | 2016-06-29 |
| JP6513632B2 (ja) | 2019-05-15 |
| US10556938B2 (en) | 2020-02-11 |
| EP2968464A4 (en) | 2016-11-09 |
| ES2883933T3 (es) | 2021-12-09 |
| RU2015144359A (ru) | 2017-04-25 |
| US20160159870A1 (en) | 2016-06-09 |
| IL241418A0 (en) | 2015-11-30 |
| BR112015021265A2 (pt) | 2017-10-10 |
| WO2014145357A2 (en) | 2014-09-18 |
| EP2968464B1 (en) | 2021-05-05 |
| US20140274915A1 (en) | 2014-09-18 |
| JP2016520531A (ja) | 2016-07-14 |
| SG11201507276UA (en) | 2015-10-29 |
| WO2014145357A3 (en) | 2014-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105722524B (zh) | 用于重组人分泌球蛋白的改进方法 | |
| US9611307B2 (en) | Method for increasing granulocyte number in a patient by administering superactive IL-33 fragments | |
| WO2007109118A9 (en) | RECOMBINANT HUMAN CC 10 (rhCC10) FOR TREATMENT OF RESPIRATORY DISORDERS | |
| EP3459556A1 (en) | Synthetic analogs of lung surfactant protein sp-c and their use | |
| CA3087835A1 (en) | Modified protein | |
| WO2021198395A1 (en) | Surfactant protein d for use in treating coronavirus infections | |
| CN110831957B (zh) | Apoc-ii模拟肽 | |
| CN106046171A (zh) | 用于防治阿尔茨海默病的融合蛋白及其制备方法和应用 | |
| CN110548135B (zh) | 磷酸化多肽抗原疫苗及其制备方法和应用 | |
| CN102134279B (zh) | 融合蛋白及其编码基因与应用 | |
| CN114853911B (zh) | 三叶因子2/干扰素α2融合蛋白及其防治病毒感染性疾病的应用 | |
| EP4530300A1 (en) | Trefoil factor 2/interferon alpha2 fusion protein and application thereof in prevention and treatment of viral infectious diseases | |
| WO2021241240A1 (ja) | 抗緑膿菌ワクチンに有用なタンパク質分子 | |
| CN106540242B (zh) | IL-1F7a的作用 | |
| WO2024235270A1 (zh) | 补体抑制剂及其制备方法和用途 | |
| HK40084128A (en) | Coronavirus antibody and use thereof | |
| WO2025114429A1 (en) | Transcytosing composition | |
| WO2023154841A2 (en) | Sars-cov-2 neutralizing synthetic proteins | |
| CN121100127A (zh) | 新型治疗性多肽 | |
| HK40064258B (zh) | 新重组二胺氧化酶及其治疗以过量组胺为特徵的疾病的用途 | |
| JP2022520862A (ja) | 新規組換えジアミンオキシダーゼおよび過剰ヒスタミンによって特徴づけられる疾患の治療のためのその使用 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200221 |