CN1057072A - 单克隆抗IgM抗体,它们的生产和用途,以及产生同样物质的杂交瘤 - Google Patents

单克隆抗IgM抗体,它们的生产和用途,以及产生同样物质的杂交瘤 Download PDF

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Publication number
CN1057072A
CN1057072A CN91102913A CN91102913A CN1057072A CN 1057072 A CN1057072 A CN 1057072A CN 91102913 A CN91102913 A CN 91102913A CN 91102913 A CN91102913 A CN 91102913A CN 1057072 A CN1057072 A CN 1057072A
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CN
China
Prior art keywords
antibody
igm
hybridoma
cell
monoclonal antibody
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN91102913A
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English (en)
Chinese (zh)
Inventor
米切尔·G·罗森布勒姆
尼克拉斯·J·多纳托
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RESEARCH DEVELOPMENT FOUDATION
Research Development Foundation
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RESEARCH DEVELOPMENT FOUDATION
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Filing date
Publication date
Application filed by RESEARCH DEVELOPMENT FOUDATION filed Critical RESEARCH DEVELOPMENT FOUDATION
Publication of CN1057072A publication Critical patent/CN1057072A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6873Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting an immunoglobulin; the antibody being an anti-idiotypic antibody
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN91102913A 1990-04-27 1991-04-27 单克隆抗IgM抗体,它们的生产和用途,以及产生同样物质的杂交瘤 Pending CN1057072A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51597490A 1990-04-27 1990-04-27
US515,974 1990-04-27

Publications (1)

Publication Number Publication Date
CN1057072A true CN1057072A (zh) 1991-12-18

Family

ID=24053580

Family Applications (1)

Application Number Title Priority Date Filing Date
CN91102913A Pending CN1057072A (zh) 1990-04-27 1991-04-27 单克隆抗IgM抗体,它们的生产和用途,以及产生同样物质的杂交瘤

Country Status (12)

Country Link
EP (1) EP0538267A4 (pt)
JP (1) JPH06504424A (pt)
CN (1) CN1057072A (pt)
CA (1) CA2079901A1 (pt)
IE (1) IE911172A1 (pt)
IL (1) IL97827A0 (pt)
NZ (1) NZ237784A (pt)
PT (1) PT97482B (pt)
RU (1) RU2105062C1 (pt)
TW (1) TW349995B (pt)
WO (1) WO1991017257A1 (pt)
ZA (1) ZA912695B (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108384761B (zh) * 2018-03-30 2020-08-11 四川迈克生物新材料技术有限公司 抗人IgM单克隆抗体、其杂交瘤细胞株及应用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2734704C (en) 2008-09-05 2017-06-20 Sekisui Medical Co., Ltd. Anti-human igm monoclonal antibody and immunoassay using the same
CN116143931B (zh) * 2021-11-20 2023-10-31 东莞市朋志生物科技有限公司 一种抗人IgM抗体及其制备方法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792447A (en) * 1981-07-23 1988-12-20 Board Of Regents, The University Of Texas System Anti-immunoglobulin toxin conjugates useful in the treatment of B cell tumors
AU9016591A (en) * 1990-10-25 1992-05-26 Tanox Biosystems, Inc. Glycoproteins associated with membrane-bound immunoglobulins as antibody targets on B cells

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108384761B (zh) * 2018-03-30 2020-08-11 四川迈克生物新材料技术有限公司 抗人IgM单克隆抗体、其杂交瘤细胞株及应用

Also Published As

Publication number Publication date
RU2105062C1 (ru) 1998-02-20
ZA912695B (en) 1993-02-24
CA2079901A1 (en) 1991-10-28
EP0538267A4 (en) 1994-06-01
JPH06504424A (ja) 1994-05-26
PT97482B (pt) 1998-08-31
IE911172A1 (en) 1991-11-06
EP0538267A1 (en) 1993-04-28
NZ237784A (en) 1992-09-25
IL97827A0 (en) 1992-06-21
WO1991017257A1 (en) 1991-11-14
AU650659B2 (en) 1994-06-30
AU7866491A (en) 1991-11-27
PT97482A (pt) 1992-01-31
TW349995B (en) 1999-01-11

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