CN105687840A - Traditional Chinese medicine preparation for treating scarlet fever and preparation - Google Patents

Traditional Chinese medicine preparation for treating scarlet fever and preparation Download PDF

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Publication number
CN105687840A
CN105687840A CN201610117781.1A CN201610117781A CN105687840A CN 105687840 A CN105687840 A CN 105687840A CN 201610117781 A CN201610117781 A CN 201610117781A CN 105687840 A CN105687840 A CN 105687840A
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preparation
chinese medicine
cortex phellodendri
medicine preparation
flos campsis
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李芳�
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488—Pueraria (kudzu)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538—Schizonepeta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a traditional Chinese medicine preparation for treating scarlet fever and preparation. The traditional Chinese medicine preparation is characterized by being prepared from, by weight, 6-8 g of amur cork-trees, 6-8 g of herba schizonepetae, 8-10 g of flos campsis, 3-4 g of duckweed, 4-6 g of Radix Salviae Miltiorrhizae, 4-6 g of Lobed Kudzuvine and 4-6 g of corn stigma. The preparation has the advantages that the medicine is prepared, essence is extracted, and the aims of dispelling wind, activating blood, promoting eruption, relieving itching and removing toxic materials are achieved.

Description

One treats scarlatinous Chinese medicine preparation and preparation
Technical field
The present invention relates to one and treat scarlatinous Chinese medicine preparation and preparation。
Background technology
It is known that scarlet fever: the Acute respiratory infectious disease caused for A group's hemolytic streptococcal infection。The product such as pathogen and toxin thereof causes inflammation and suppurative change at infestation position and surrounding tissue thereof, and enters blood circulation, causes septicemia, pyrogenicity toxin to cause heating and erythema。Main pathological change is dermal layer of the skin capillary injection, edema, and epidermis has inflammatory exudation, perifollicolar hydroderma, epithelial hyperplasia and inflammatory cell infiltration, shows as pimple sample Corium Gallus domesticus rash, and convalescent period keratinization of epidermis, necrosis, sheet comes off。The visible toxic myocarditis of minority, liver, spleen, lymph node hyperemia etc. change。Its Clinical symptoms is that heating, angina, whole body diffusivity cerise erythra and rash step back obvious desquamation。The infringement in the heart, kidney, joint occurs due to allergy after small number of patients is ill。Primary disease has generation throughout the year, especially to fall ill for many in the season of Winter-Spring。See children's, especially with 5-15 year in the majority。The traditional Chinese medical science is thought: the heresy of acute diseases such as cholera and sunstroke poison epidemic disease is invaded lung and defended, and lung stomach is by heresy, and its gas is become estranged, and heresy enters nutrient blood can increase the weight of the state of an illness further。
Summary of the invention
Chinese medicine of the present invention provides the benefit that: by by processing of medical material, skim the cream off milk reach dispel the wind, invigorate blood circulation, the purpose of rash, antipruritic, toxin expelling, clinical often according to different disease type determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs。
The technical problem to be solved is to overcome technical deficiency, it is provided that a kind of good effect, short treating period, cure rate are high, and the one having no side effect treats scarlatinous Chinese medicine preparation and preparation。
For realizing object above, one treats scarlatinous Chinese medicine preparation and preparation, it is characterized in that being made up of the crude drug of following weight: Cortex Phellodendri 6～8g, Herba Schizonepetae 6～8g, Flos Campsis 8～10g, Herba Spirodelae 3～4g, Radix Salviae Miltiorrhizae 4～6g, Pachyrhizua angulatus 4～6g, Stigma Maydis 4～6g。
Manufacture method: first by Cortex Phellodendri levigation salt adding in 10: 0.5 ratios, add water in 1: 2 ratio, soak 24 hours, take filtrate and be evaporated into stir-baked CORTEX PHELLODENDRI with salt solution powder；Herba Schizonepetae, Flos Campsis, Stigma Maydis are added 10 times of water, adds hot water and fly 2 times, each 30 minutes, take filtrate standby；Again by Herba Spirodelae, Rhizoma Phragmitis, Pachyrhizua angulatus adds 6 times of 65% alcoholic solution, is heated to reflux 30 minutes, then by residue boiling 2 times, each 1 hour, takes filtrate and filter, reclaim ethanol；To filter and stir-baked CORTEX PHELLODENDRI with salt solution powder, Herba Schizonepetae, Flos Campsis, the mixing of Stigma Maydis filtrate, adding dextrin mixes in 1: 1 ratio, is concentrated into the extractum that relative density is 1.15-1.25 (80 DEG C), to obtain final product again。
Stir-baked CORTEX PHELLODENDRI with salt solution effect in Chinese medicine of the present invention: stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire。For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency。Herba Schizonepetae effect: induce sweat scattered wind, rash, and disappear skin ulcer。For catching a cold, headache, measles, rubella, skin infection from the beginning of。Flos Campsis is sweet, sour, cold。Return liver, pericardium channel。Effect: promoting blood circulation to restore menstrual flow, cooling blood, expelling wind。For menoxenia, amenorrhea, abdominal mass, puerperal swelling of the breast, rubella is rubescent, skin pruritus, acne。Flos Campsis Herba Spirodelae effect: dispelling wind-heat, rash, diuresis。For measles without adequate eruption, rubella pruritus, edema oliguria。Pachyrhizua angulatus effect: expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, rash, yang invigorating antidiarrheal, dredge the meridian passage, alcoholic intoxication。Have a headache for fever caused by exogenous pathogens, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption ...。Radix Salviae Miltiorrhizae is dry root and the rhizome of labiate Radix Salviae Miltiorrhizae SalviamiltiorrhizaBge.。Having blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle。Stigma Maydis effect: inducing diuresis to remove edema, dampness removing jaundice eliminating。For edema oliguria, jaundice due to damp-heat, dizzy blurred vision。Above medicine is arranged in pairs or groups, and the treatment to this disease brings out the best in each other。
The present invention follows the prescriptions principle of the traditional Chinese medical science, verifies through clinical application for many years, and effective percentage is 100%, cure rate more than 90%。
Detailed description of the invention
Below in conjunction with implementing case, the invention will be further described:
Embodiment 1: one treats scarlatinous Chinese medicine preparation and preparation, it is characterized in that being made up of the crude drug of following weight: Cortex Phellodendri 6～8g, Herba Schizonepetae 6～8g, Flos Campsis 8～10g, Herba Spirodelae 3～4g, Radix Salviae Miltiorrhizae 4～6g, Pachyrhizua angulatus 4～6g, Stigma Maydis 4～6g。Preparation method is with above-mentioned。
Embodiment 2: one treats scarlatinous Chinese medicine preparation and preparation, is characterized in that being made up of the crude drug of following weight: Cortex Phellodendri 8g, Herba Schizonepetae 8g, Flos Campsis 8g, Herba Spirodelae 4g, Radix Salviae Miltiorrhizae 6g, Pachyrhizua angulatus 6g, Stigma Maydis 4g。Preparation method, with embodiment 1, obtains unguentum 100g, is distributed into 20 bags, often comprises 5g。
Clinical efficacy is summed up
One, physical data: the Chinese medicine of the present invention, applies for many years clinically, treats patient's example up to a hundred, and effect frequency is good。
Two, diagnostic criteria: 1. contact history has and scarlet fever or angina patient contact history person, contributes to diagnosis。2. clinical manifestation: rapid heating, angina, typical erythra, circumoral pallor, strawberry-like tongue, pastia line, convalescent period decortication etc., for scarlatinous feature。3. lab testing: leukocyte count increases, neutrophil cell accounts for more than 80%。Erythrogenic toxin test early stage is positive。Pharynx swab, pus are cultivated and can be obtained A group B streptococcus。
Three, method of administration: take unguentum, early, takes orally for late twice, within 10～12 years old, often each 1 wraps；Within 5～10 years old, each 1/2 bag is for oral administration；It within 1 week, it was 1 course for the treatment of。
Four, curative effect judging standard:
Cure: rash backheat is moved back, transference cure, hemogram recover normal。
Take a turn for the better: rash backheat is moved back, and clinical symptoms is taken a turn for the better。
Invalid: the state of an illness fails to control or develop complications。
Five, therapeutic effect: clinical application for many years, through statistics effective percentage 100%, cure rate more than 90%。
Six, model case:
1, high X, female, 12 years old。Student。In June, 2012 goes to a doctor, and patient and mother describe, and occurs that pharyngalgia, last night start heating, whole body diffusivity cerise erythra before 1 week, and through improving inconspicuous by antibiotic medicine symptom, erythra is stepped up。Lab testing: leukocyte increases。The head of a family requires for oral administration Chinese medicine 1 of the present invention course for the treatment of, and deflorescence, hemogram recovers normal, follows up a case by regular visits to half a year and does not recur again。
2, in XX, man, 9 years old, student。In July, 2013 goes to a doctor, and the head of a family, generates heat over 2 days for main suit, erythra, angina, circumoral pallor, strawberry-like tongue, pastia line。Take medicine 5 days with Roxithromycin。Poor effect。Laboratory: leukocyte and neutrophil cell increase；Throat swab is cultivated as A group beta hemolytic streptococcus。The head of a family requires for oral administration Chinese medicine 2 of the present invention course for the treatment of, and deflorescence, hemogram recovers normal, follows up a case by regular visits to half a year and does not recur again。
3, Dong X, female, 6 years old。In May, 2015 goes to a doctor, the head of a family uncomfortable 2 days for main suit entire patient, and heating, whole body diffusivity cerise erythra were gone to a doctor in April, 2010, and doctor prescribed cephamycin is injected, and the head of a family is reluctant to accept。The head of a family requires for oral administration Chinese medicine 1 of the present invention course for the treatment of, and clinical symptoms is wholly absent, and follows up a case by regular visits to half a year and does not recur again。

Claims (2)

1. treat scarlatinous Chinese medicine preparation and a preparation, it is characterized in that being made up of the crude drug of following weight: Cortex Phellodendri 6～8g, Herba Schizonepetae 6～8g, Flos Campsis 8～10g, Herba Spirodelae 3～4g, Radix Salviae Miltiorrhizae 4～6g, Pachyrhizua angulatus 4～6g, Stigma Maydis 4～6g。
2. according to claim 1 one kind treat scarlatinous Chinese medicine preparation and preparation manufacture method: it is characterized in that first by Cortex Phellodendri levigation salt adding in 10: 0.5 ratios, add water in 1: 2 ratio, soak 24 hours, take filtrate and be evaporated into stir-baked CORTEX PHELLODENDRI with salt solution powder；Herba Schizonepetae, Flos Campsis, Stigma Maydis are added 10 times of water, adds hot water and fly 2 times, each 30 minutes, take filtrate standby；Again by Herba Spirodelae, Rhizoma Phragmitis, Pachyrhizua angulatus adds 60% ethanol, is heated to reflux 30 minutes, residue boiling 2 times, each 1 hour, takes filtrate and filters, reclaims ethanol；To filter and stir-baked CORTEX PHELLODENDRI with salt solution powder, Herba Schizonepetae, Flos Campsis, the mixing of Stigma Maydis filtrate, adding dextrin mixes in 1: 1 ratio, is concentrated into the extractum that relative density is 1.15-1.25 (80 DEG C), to obtain final product again。
CN201610117781.1A 2016-02-26 2016-02-26 Traditional Chinese medicine preparation for treating scarlet fever and preparation Pending CN105687840A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107823417A (en) * 2017-12-28 2018-03-23 马建国 A kind of scarlet fever fash for the treatment of steps back medicine oil for causing the desquamation of skin and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107823417A (en) * 2017-12-28 2018-03-23 马建国 A kind of scarlet fever fash for the treatment of steps back medicine oil for causing the desquamation of skin and preparation method thereof

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Application publication date: 20160622