CN105687555A - 一种用于治疗糖尿病的药物制剂 - Google Patents

一种用于治疗糖尿病的药物制剂 Download PDF

Info

Publication number
CN105687555A
CN105687555A CN201610121143.7A CN201610121143A CN105687555A CN 105687555 A CN105687555 A CN 105687555A CN 201610121143 A CN201610121143 A CN 201610121143A CN 105687555 A CN105687555 A CN 105687555A
Authority
CN
China
Prior art keywords
parts
pharmaceutical preparation
diabetes
treating
add
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610121143.7A
Other languages
English (en)
Inventor
冯字
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610121143.7A priority Critical patent/CN105687555A/zh
Publication of CN105687555A publication Critical patent/CN105687555A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/884—Alismataceae (Water-plantain family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)

Abstract

本发明属于中药制剂领域，具体提供了一种治疗糖尿病的药物制剂，它由如下原料制备得到：唢呐花25份、楔叶葎20份、芭蕉头18份、过江龙20份、鸡爪风20份、泽泻18份、五味子20份、覆盆子25份、鱼腥草25份、丹参20份、茯苓20份、甘草5份，本发明能治疗糖尿病。

Description

一种用于治疗糖尿病的药物制剂
技术领域
本发明涉及中药制剂技术领域，具体涉及一种用于治疗糖尿病的药物制剂及其制备方法和应用。
背景技术
糖尿病是由遗传因素、免疫功能紊乱、微生物感染及其毒素、自由基毒素、精神因素等等各种致病因子作用于机体导致胰岛功能减退、胰岛素抵抗等而引发的糖、蛋白质、脂肪、水和电解质等一系列代谢紊乱综合征，临床上以高血糖为主要特点，典型病例可出现多尿、多饮、多食、消瘦等表现，即“三多一少”症状，糖尿病(血糖)一旦控制不好会引发并发症，导致肾、眼、足等部位的衰竭病变，且无法治愈。为此，急要开发出更多安全有效的治疗糖尿病的药物满足临床治疗的需要。
发明内容
为了解决上述问题，本发明的目的在于提供一种可治疗糖尿病疾病的中药制剂。为了达到这个目的，采用如下技术方案：
技术方案：一种用于治疗糖尿病的药物制剂，它所含的活性成分由下列重量份原料药提取制备而成：唢呐花25份、楔叶葎20份、芭蕉头18份、过江龙20份、鸡爪风20份、泽泻18份、五味子20份、覆盆子25份、鱼腥草25份、丹参20份、茯苓20份、甘草5份。
所述用于治疗糖尿病的药物制剂，剂型是药学上可接受的颗粒剂、片剂、胶囊剂。
所述用于治疗糖尿病的药物制剂，制备步骤为：取上述中药，加药材10倍重量的水，浸泡0.5h，煎煮1小时，过滤，药渣再加入药材8倍重量的水，煎煮1小时，药液滤出，合并两次煎煮液，减压浓缩至60℃相对密度为1.05，加乙醇使含醇量的体积百分比达75％，搅拌，静置，过滤，滤液减压浓缩至65℃时相对密度为1.25，并回收乙醇，得浓缩液，将浓缩液喷雾干燥，喷雾干燥条件为：进风温度为100℃，出风温度为90℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为10ml/s，添加辅料制成胶囊剂、片剂、颗粒剂。
所述用于治疗糖尿病的药物制剂在制备治疗糖尿病药物中的应用。
唢呐花为角蒿属植物毛子草Incarvilleaarguta(Royle)Royle，以根状茎或全草入药。秋季采收，洗净切片，晒干。祛风除湿，消炎止痛，活血散瘀。用于风湿骨痛，月经不调；外用治疮疖，痈肿，骨折。本发明采用全草入药。
楔叶葎，拉丁名为GaliumasperifoliumWall.exRoxb.，多年生、蔓生或攀缘草本，高约20-70厘米，分枝多，扩展。产广西，云南，西藏。全草：清热解毒，除风祛湿，消肿散瘀，利尿通淋，止血。用于痰火热症，风热眼雾，风湿痛，淋浊，尿血，中耳炎，跌打肿痛，虚痨，筋骨痛，痛经，外伤瘀肿，肠痈，疖肿。根：舒筋活络。用于目赤肿痛，月经不调，跌打损伤。本发明以全草入药。
芭蕉头为芭蕉科芭蕉属植物芭蕉MusabasjooSiebetZucc.，以根、茎和花入药。根及茎四季可采，洗净鲜用或晒干；夏秋采花蕾，多鲜用。清热解毒，利尿消肿，凉血，止痛。用于感冒咳嗽，头痛，高血压病，胃痛，腹痛，肝炎，痢疾，崩漏，胎动不安，尿路感染，水肿；外用治中耳炎，创伤出血，痈疖肿毒。本发明以根入药。
过江龙为石松科植物扁枝石枝的全草或孢子，拉丁植物名：Diphasiastrumcomplanatum(L.)Holub.[LycopodiumcomplanatumL.，治疗暑热痢疾，伤暑发热，小便不利，风火牙痛，小儿麻疹；外治皮肤疮疡热毒，丹毒，飞疡疮，飞蛇卵。本发明以全草入药。
鸡爪风为番荔枝科假鹰爪属植物假鹰爪DesmoscochinchinensisLour.，以根及全株入药。全年可采，洗净切碎晒干。祛风利湿，健脾理气，祛瘀止痛。用于风湿关节痛，产后风痛，产后腹痛、流血不止，痛经，胃痛，胃痛，腹胀，消化不良，腹泻，肾炎水肿，跌打损伤。本发明以根入药。其余中药为药典品种。
有益效果：糖尿病为饮食不节、情志失调、劳欲过度、素体虚弱等因素均可导致，本发明唢呐花、楔叶葎、芭蕉头、过江龙、鸡爪风、泽泻清热解毒、滋阴降火为君药，五味子、覆盆子、鱼腥草、丹参、茯苓健脾化湿、活血祛瘀、补益气血为臣药，甘草为佐使药，全方相互配伍，治疗糖尿病效果明显。
具体实施方式
以下通过实施例形式，对本发明的上述内容再作进一步的详细说明，但不应将此理解为本发明上述主题的范围仅限于以下的实例，凡基于本发明上述内容所实现的技术均属于本发明的范围。
1、颗粒剂实施例的制备：取唢呐花25g、楔叶葎20g、芭蕉头18g、过江龙20g、鸡爪风20g、泽泻18g、五味子20g、覆盆子25g、鱼腥草25g、丹参20g、茯苓20g、甘草5g，加药材10倍重量的水，浸泡0.5h，煎煮1小时，过滤，药渣再加入药材8倍重量的水，煎煮1小时，药液滤出，合并两次煎煮液，减压浓缩至60℃相对密度为1.05，加乙醇使含醇量的体积百分比达75％，搅拌，静置，过滤，滤液减压浓缩至65℃时相对密度为1.25，并回收乙醇，得浓缩液，将浓缩液喷雾干燥，喷雾干燥条件为：进风温度为100℃，出风温度为90℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为10ml/s，添加淀粉50g，制粒，制成颗粒剂。
2、片剂实施例的制备：取唢呐花25g、楔叶葎20g、芭蕉头18g、过江龙20g、鸡爪风20g、泽泻18g、五味子20g、覆盆子25g、鱼腥草25g、丹参20g、茯苓20g、甘草5g，加药材10倍重量的水，浸泡0.5h，煎煮1小时，过滤，药渣再加入药材8倍重量的水，煎煮1小时，药液滤出，合并两次煎煮液，减压浓缩至60℃相对密度为1.05，加乙醇使含醇量的体积百分比达75％，搅拌，静置，过滤，滤液减压浓缩至65℃时相对密度为1.25，并回收乙醇，得浓缩液，将浓缩液喷雾干燥，喷雾干燥条件为：进风温度为100℃，出风温度为90℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为10ml/s，添加糊精50g，制粒，压片，制成片剂。
3、胶囊剂实施例的制备：取唢呐花25g、楔叶葎20g、芭蕉头18g、过江龙20g、鸡爪风20g、泽泻18g、五味子20g、覆盆子25g、鱼腥草25g、丹参20g、茯苓20g、甘草5g，加药材10倍重量的水，浸泡0.5h，煎煮1小时，过滤，药渣再加入药材8倍重量的水，煎煮1小时，药液滤出，合并两次煎煮液，减压浓缩至60℃相对密度为1.05，加乙醇使含醇量的体积百分比达75％，搅拌，静置，过滤，滤液减压浓缩至65℃时相对密度为1.25，并回收乙醇，得浓缩液，将浓缩液喷雾干燥，喷雾干燥条件为：进风温度为100℃，出风温度为90℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为10ml/s，添加淀粉50g，制粒，灌装，制成胶囊剂。
4、本发明药物制剂治疗糖尿病临床研究
4.1一般性资料：本药物制剂应用于临床观察糖尿病病例50例，年龄39～64岁。病程最短者3个月，最长者达5年。
4.2诊断标准：(1)口渴多饮，多食易饥，尿频量多，形体消瘦；(2)初起可“三多”症状不著。病久常并发眩晕、肺痨、胸痹、中风、雀目、疮疖等。严重者可见烦渴、头痛、呕吐、腹痛、呼吸短促，甚或昏迷厥脱危象；(3)查空腹、餐后2小时尿糖和血糖、尿比重、葡萄糖耐量试验。必要时查尿酮体、血尿素氮、肌酐、二氧化碳结合力及血钾、钠、钙、氯化物等。
4.3试验方法：按上述颗粒剂制备方法制备临床样品，规格为每袋10克，五天为一疗程，一天三袋，分早、中、晚三次饭前半小时服用。服药期间忌食生冷、辛辣、刺激及腐烂之物。空白组口服安慰剂颗粒剂，一个月为一疗程，一天三袋，分早、中、晚三次饭前半小时服用。
4.4疗效标准：痊愈：症状消失，实验室检查多次正常；有效：主要症状及有关实验室检查有改善；无效：症状及实验室检查无变化。
4.5治疗效果：见表1。
表1两组疗效比较
组别 n 痊愈 有效 无效 总有效率(％)
治疗组 25 2 19 4 84
空白组 25 1 1 23 8
可见，本发明制得的药物能够安全有效治疗糖尿病，且无毒副作用。

Claims (4)

1.一种用于治疗糖尿病的药物制剂，其特征在于，它所含的活性成分由下列重量份原料药提取制备而成：唢呐花25份、楔叶葎20份、芭蕉头18份、过江龙20份、鸡爪风20份、泽泻18份、五味子20份、覆盆子25份、鱼腥草25份、丹参20份、茯苓20份、甘草5份。
2.如权利要求1所述用于治疗糖尿病的药物制剂，其特征在于，剂型是药学上可接受的颗粒剂、片剂、胶囊剂。
3.如权利要求1所述用于治疗糖尿病的药物制剂，其特征在于，制备步骤为：取上述中药，加药材10倍重量的水，浸泡0.5h，煎煮1小时，过滤，药渣再加入药材8倍重量的水，煎煮1小时，药液滤出，合并两次煎煮液，减压浓缩至60℃相对密度为1.05，加乙醇使含醇量的体积百分比达75％，搅拌，静置，过滤，滤液减压浓缩至65℃时相对密度为1.25，并回收乙醇，得浓缩液，将浓缩液喷雾干燥，喷雾干燥条件为：进风温度为100℃，出风温度为90℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为10ml/s，添加辅料制成胶囊剂、片剂、颗粒剂。
4.根据权利要求1所述用于治疗糖尿病的药物制剂在治疗糖尿病药物中的应用。
CN201610121143.7A 2016-03-03 2016-03-03 一种用于治疗糖尿病的药物制剂 Pending CN105687555A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610121143.7A CN105687555A (zh) 2016-03-03 2016-03-03 一种用于治疗糖尿病的药物制剂

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610121143.7A CN105687555A (zh) 2016-03-03 2016-03-03 一种用于治疗糖尿病的药物制剂

Publications (1)

Publication Number Publication Date
CN105687555A true CN105687555A (zh) 2016-06-22

Family

ID=56223861

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610121143.7A Pending CN105687555A (zh) 2016-03-03 2016-03-03 一种用于治疗糖尿病的药物制剂

Country Status (1)

Country Link
CN (1) CN105687555A (zh)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105106627A (zh) * 2015-10-08 2015-12-02 南京市栖霞区回春堂电子商务咨询中心 一种用于治疗糖尿病的药物制剂
CN105148074A (zh) * 2015-09-29 2015-12-16 南京晶云化工有限公司 一种用于治疗糖尿病的药物制剂

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105148074A (zh) * 2015-09-29 2015-12-16 南京晶云化工有限公司 一种用于治疗糖尿病的药物制剂
CN105106627A (zh) * 2015-10-08 2015-12-02 南京市栖霞区回春堂电子商务咨询中心 一种用于治疗糖尿病的药物制剂

Similar Documents

Publication Publication Date Title
CN102225138B (zh) 一种用于治疗骨折的中药组合物及其制备方法和应用
CN103083433B (zh) 一种治疗风湿和风湿性坐骨神经痛的药物
CN104435567A (zh) 一种含绞股蓝的治疗痛风的中药组合物
CN104337989A (zh) 一种含鹅不食草和乳香的治疗痛风的中药组合物
CN105031497A (zh) 一种用于治疗慢性胃炎的药物制剂
CN105267711A (zh) 一种用于治疗眩晕症的药物制剂
CN105031439A (zh) 一种用于治疗慢性牙周炎的药物制剂
CN105055924A (zh) 一种用于治疗偏头痛的药物制剂
CN105687555A (zh) 一种用于治疗糖尿病的药物制剂
CN103690771B (zh) 用于治疗羔羊大肠杆菌病的药物及其制备方法
CN103599419B (zh) 一种治疗痛风的中药组合物
CN105288285A (zh) 一种用于治疗慢性支气管炎的药物制剂
CN105148074A (zh) 一种用于治疗糖尿病的药物制剂
CN105169064A (zh) 一种用于美白皮肤的药物制剂
CN105031481A (zh) 一种用于治疗神经衰弱的药物制剂
CN105106764A (zh) 一种用于治疗妊娠呕吐的药物制剂
CN104873879A (zh) 一种用于治疗失眠的药物制剂
CN106266971A (zh) 一种用于治疗乳腺增生的药物制剂
CN105106684A (zh) 一种用于治疗肝阳上亢型高血压的药物制剂
CN105055845A (zh) 一种用于治疗心脏供血不足的药物制剂
CN105148078A (zh) 一种用于治疗口腔溃疡的药物制剂
CN105079717A (zh) 一种用于治疗抑郁症的药物制剂
CN105106817A (zh) 治疗糖尿病的瑶药复方追骨风片剂及其制备方法
CN104042924A (zh) 一种治疗气血亏虚型骨性关节炎的中药制剂及其制备方法
CN105232827A (zh) 一种用于治疗肾结石的药物制剂

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20160622