CN105685426A - Special feed for laboratory mice and preparation method thereof - Google Patents
Special feed for laboratory mice and preparation method thereof Download PDFInfo
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- CN105685426A CN105685426A CN201410696733.3A CN201410696733A CN105685426A CN 105685426 A CN105685426 A CN 105685426A CN 201410696733 A CN201410696733 A CN 201410696733A CN 105685426 A CN105685426 A CN 105685426A
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Abstract
The present invention discloses a special feed for laboratory mice and a preparation method thereof, and relates to the technical field of laboratory animal feed. The special feed for experiment mice is composed of the following raw materials by weight: 30-40 parts of corn, 20-40 parts of flour, 20-40 parts of rice, 20-40 parts of soybean, 10-20 parts of fish meal, 5-8 parts of elderberry powder, 3-5 parts of eggshell powder, 1-3 parts of lotus powder, 3-5 parts of sucrose, 1-3 parts of fructose, 1-3 parts of vegetable oil, 1-3 parts of lard, 0.1-0.3 parts of a mineral salt premix, 0.1-0.3 part of an amino acid premix, 0.1-0.2 part of a vitamin premix, and 0.1-0.2 part of a trace element premix. The feed employs high quality ingredients in reasonable ratio, not only meets the nutritional needs of growth and development of laboratory mice but also is free of heavy metals and pesticide residues, so as to ensure the health of the mice, and avoid affects on experimental results.
Description
Technical field
The present invention relates to laboratory animal field of feed, particularly relate to a kind of experiment mice special feed and preparation method thereof。
Background technology
Laboratory animal refers to through artificial feeding, and its microorganism carried, parasite are carried out and controlled, and genetic background clearly or is originated clearly, for the animal of scientific research, teaching, production, calibrating and other scientific experimentss。Laboratory animal is a kind of lived experimental subject, is described as " reagent lived ", " instrument lived ", embodies laboratory animal significance in quality management。The factor affecting Quality of Experimental Animals is many-sided, such as heredity, environment, drinking-water, feedstuff etc.。Laboratory animal feeding quality is essential condition closely-related with Quality of Experimental Animals, is also to ensure that zoopery is smoothed out basic accurately and reliably with experimental result。Laboratory animal feed hygiene safety and harm are attached great importance to by developed country, and it, along with the enforcement of GLP, is also increasingly paid close attention to and pay attention to by China。
The factor affecting Quality of Experimental Animals includes chemical factor, microbiological factor and trophic factor etc.。Chemical factor includes the mineral in feedstuff, trace element and content of beary metal, residual pesticide；Trophic factor includes the content of the nutrient substance such as protein, vitamin in feedstuff。In laboratory animal feedstuff, the equilibrium of each nutritional labeling is the premise that laboratory animal is grown up healthy and sound, and is to ensure that the basic condition of Quality of Experimental Animals。Laboratory animal is as " instrument lived ", and only eutrophy, body is well-balanced, is just suitable for medical research and the Quality Identification of medicine, biological product。
But at present, owing to the research of the special feed to experiment mice is also extremely limited, it is impossible to meeting the g and D demand of big mice, influencer mice grows normally to some extent。In consideration of it, be necessary to continue research on this basis, develop applicable mouse growth, experimental result is not produced the special feed of impact。
Summary of the invention
The goal of the invention of the present invention is in that: for above-mentioned Problems existing, there is provided a kind of experiment mice special feed, and preparation method thereof, the preferred feedstuff of feedstuff of the present invention, carry out rational proportion, the nutritional need of the growth promoter of experiment mice can not only be met, also without heavy metal, pesticide residues, can guarantee that the health of experiment mice, do not affect and it is carried out the experimental result of every experiment。
The technical solution used in the present invention is as follows:
A kind of experiment mice special feed, is made up of the raw material of following weight portion: Semen Maydis 30-40 part, flour 20-40 part, rice 20-40 part, bean cake 20-40 part, fish flour 10-20 part, Gallus jabouillei tea powder 5-8 part, egg-shell meal 3-5 part, Folium Nelumbinis powder 1-3 part, sucrose 3-5 part, fructose 1-3 part, vegetable oil 1-3 part, Adeps Sus domestica 1-3 part, mineral salt premix material 0.1-0.3 part, aminoacid premix material 0.1-0.3 divides, vitamin premix 0.1-0.2 part, microelement pre-mix material 0.1-0.2 part。
Further, above-mentioned experiment mice special feed, it is made up of the raw material of following weight portion: Semen Maydis 35-38 part, flour 25-35 part, rice 25-35 part, bean cake 25-35 part, fish flour 15-18 part, Gallus jabouillei tea powder 6-8 part, egg-shell meal 3-4 part, Folium Nelumbinis powder 1-2 part, sucrose 3-4 part, fructose 1-2 part, vegetable oil 1-3 part, Adeps Sus domestica 1-3 part, mineral salt premix material 0.1-0.3 part, aminoacid premix material 0.1-0.3 divides, vitamin premix 0.1-0.2 part, microelement pre-mix material 0.1-0.2 part。
Further, described fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder, sucrose, fructose were the fine powder of 200-300 mesh sieve。
The preparation method that the present invention also provides for a kind of experiment mice special feed, comprises the following steps:
(1) Semen Maydis, rice, bean cake are put into respectively pulverizer and pulverizes the fine powder obtaining 200-300 mesh sieve；
(2) all raw material powders are got out according to the proportioning of each raw material, the powder raw material that will weigh, put into mixing 10-20min in mixer including Semen Maydis powder, rice meal, bean cake powder, flour, fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder raw material；
(3) after fully being mixed by various raw materials, add vegetable oil, Adeps Sus domestica, mineral salt premix material, aminoacid premix material, vitamin premix, microelement pre-mix material, mix 10-15min；
(4) by mixed material pelletize in comminutor, diameter 3-5mm, length 8-15mm pellet is obtained。
In sum, owing to have employed technique scheme, the invention has the beneficial effects as follows: the selected feedstuff of feedstuff of the present invention, carry out rational proportion, its nutrition is very comprehensive, can not only meet the nutritional need of the growth promoter of experiment mice, possibly together with composition Gallus jabouillei tea and the Folium Nelumbinis of the disease propagation can prevented between experiment mice, can guarantee that the health of experiment mice, do not affect and it is carried out the experimental result of every experiment。
Detailed description of the invention
Below by way of detailed description of the invention, the invention will be further described。
Embodiment 1
A kind of experiment mice special feed, is made up of the raw material of following weight portion: Semen Maydis 30 parts, 20 parts of flour, 20 parts of rice, bean cake 20 parts, fish flour 10 parts, Gallus jabouillei tea powder 5 parts, egg-shell meal 3 parts, 1 part of Folium Nelumbinis powder, sucrose 3 parts, 1 part of fructose, vegetable oil 1 part, Adeps Sus domestica 1 part, mineral salt premix material 0.1 part, aminoacid premix material 0.1 point, vitamin premix 0.1 part, microelement pre-mix material 0.1 part。
Wherein, above-mentioned fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder, sucrose, fructose were the fine powder of 200 mesh sieves。
The method preparing above-mentioned a kind of experiment mice special feed, comprises the following steps:
(1) Semen Maydis, rice, bean cake are put into respectively pulverizer and pulverizes the fine powder obtaining 200 mesh sieves；
(2) all raw material powders are got out according to the proportioning of each raw material, the powder raw material that will weigh, put into mixing 10min in mixer including Semen Maydis powder, rice meal, bean cake powder, flour, fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder raw material；
(3) after fully being mixed by various raw materials, add vegetable oil, Adeps Sus domestica, mineral salt premix material, aminoacid premix material, vitamin premix, microelement pre-mix material, mix 10min；
(4) by mixed material pelletize in comminutor, diameter 3mm, length 8mm pellet is obtained。
Embodiment 2
A kind of experiment mice special feed, is made up of the raw material of following weight portion: Semen Maydis 35 parts, 25 parts of flour, 25 parts of rice, bean cake 25 parts, fish flour 15 parts, Gallus jabouillei tea powder 6 parts, egg-shell meal 3 parts, 1 part of Folium Nelumbinis powder, sucrose 3 parts, 1 part of fructose, vegetable oil 1 part, Adeps Sus domestica 1 part, mineral salt premix material 0.1 part, aminoacid premix material 0.1 part, vitamin premix 0.1 part, microelement pre-mix material 0.1 part。
Wherein, above-mentioned fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder, sucrose, fructose were the fine powder of 300 mesh sieves。
The method preparing above-mentioned a kind of experiment mice special feed, comprises the following steps:
(1) Semen Maydis, rice, bean cake are put into respectively pulverizer and pulverizes the fine powder obtaining 300 mesh sieves；
(2) all raw material powders are got out according to the proportioning of each raw material, the powder raw material that will weigh, put into mixing 20min in mixer including Semen Maydis powder, rice meal, bean cake powder, flour, fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder raw material；
(3) after fully being mixed by various raw materials, add vegetable oil, Adeps Sus domestica, mineral salt premix material, aminoacid premix material, vitamin premix, microelement pre-mix material, mix 15min；
(4) by mixed material pelletize in comminutor, diameter 5mm, length 8-15mm pellet is obtained。
Embodiment 3
A kind of experiment mice special feed, is made up of the raw material of following weight portion: Semen Maydis 40 parts, 40 parts of flour, 40 parts of rice, bean cake 40 parts, fish flour 20 parts, Gallus jabouillei tea powder 8 parts, egg-shell meal 5 parts, 3 parts of Folium Nelumbinis powder, sucrose 5 parts, 3 parts of fructose, vegetable oil 3 parts, Adeps Sus domestica 3 parts, mineral salt premix material 0.3 part, aminoacid premix material 0.3 point, vitamin premix 0.2 part, microelement pre-mix material 0.2 part。
Wherein, above-mentioned fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder, sucrose, fructose were the fine powder of 200 mesh sieves。
The method preparing above-mentioned a kind of experiment mice special feed, comprises the following steps:
(1) Semen Maydis, rice, bean cake are put into respectively pulverizer and pulverizes the fine powder obtaining 200 mesh sieves；
(2) all raw material powders are got out according to the proportioning of each raw material, the powder raw material that will weigh, put into mixing 10min in mixer including Semen Maydis powder, rice meal, bean cake powder, flour, fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder raw material；
(3) after fully being mixed by various raw materials, add vegetable oil, Adeps Sus domestica, mineral salt premix material, aminoacid premix material, vitamin premix, microelement pre-mix material, mix 10min；
(4) by mixed material pelletize in comminutor, diameter 3mm, length 8-15mm pellet is obtained。
Embodiment 4
A kind of experiment mice special feed, is made up of the raw material of following weight portion: Semen Maydis 38 parts, 35 parts of flour, 35 parts of rice, bean cake 35 parts, fish flour 18 parts, Gallus jabouillei tea powder 8 parts, egg-shell meal 4 parts, 2 parts of Folium Nelumbinis powder, sucrose 4 parts, 2 parts of fructose, vegetable oil 3 parts, Adeps Sus domestica 3 parts, mineral salt premix material 0.3 part, aminoacid premix material 0.3 point, vitamin premix 0.2 part, microelement pre-mix material 0.2 part。
Wherein, above-mentioned fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder, sucrose, fructose were the fine powder of 200 mesh sieves。
The method preparing above-mentioned a kind of experiment mice special feed, comprises the following steps:
(1) Semen Maydis, rice, bean cake are put into respectively pulverizer and pulverizes the fine powder obtaining 200 mesh sieves；
(2) all raw material powders are got out according to the proportioning of each raw material, the powder raw material that will weigh, put into mixing 10min in mixer including Semen Maydis powder, rice meal, bean cake powder, flour, fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder raw material；
(3) after fully being mixed by various raw materials, add vegetable oil, Adeps Sus domestica, mineral salt premix material, aminoacid premix material, vitamin premix, microelement pre-mix material, mix 10min；
(4) by mixed material pelletize in comminutor, diameter 4mm, length 10mm pellet is obtained。
Claims (4)
1. an experiment mice special feed, it is characterised in that be made up of the raw material of following weight portion: Semen Maydis 30-40 part, flour 20-40 part, rice 20-40 part, bean cake 20-40 part, fish flour 10-20 part, Gallus jabouillei tea powder 5-8 part, egg-shell meal 3-5 part, Folium Nelumbinis powder 1-3 part, sucrose 3-5 part, fructose 1-3 part, vegetable oil 1-3 part, Adeps Sus domestica 1-3 part, mineral salt premix material 0.1-0.3 part, aminoacid premix material 0.1-0.3 divides, vitamin premix 0.1-0.2 part, microelement pre-mix material 0.1-0.2 part。
2. a kind of experiment mice special feed according to claim 1, it is characterized in that being made up of the raw material of following weight portion: Semen Maydis 35-38 part, flour 25-35 part, rice 25-35 part, bean cake 25-35 part, fish flour 15-18 part, Gallus jabouillei tea powder 6-8 part, egg-shell meal 3-4 part, Folium Nelumbinis powder 1-2 part, sucrose 3-4 part, fructose 1-2 part, vegetable oil 1-3 part, Adeps Sus domestica 1-3 part, mineral salt premix material 0.1-0.3 part, aminoacid premix material 0.1-0.3 divides, vitamin premix 0.1-0.2 part, microelement pre-mix material 0.1-0.2 part。
3. a kind of experiment mice special feed according to claim 1, it is characterised in that: described fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder, sucrose, fructose were the fine powder of 200-300 mesh sieve。
4. the preparation method of a kind of experiment mice special feed according to claim 1,2 or 3, it is characterised in that comprise the following steps:
(1) Semen Maydis, rice, bean cake are put into respectively pulverizer and pulverizes the fine powder obtaining 200-300 mesh sieve；
(2) all raw material powders are got out according to the proportioning of each raw material, the powder raw material that will weigh, put into mixing 10-20min in mixer including Semen Maydis powder, rice meal, bean cake powder, flour, fish flour, Gallus jabouillei tea powder, egg-shell meal, Folium Nelumbinis powder raw material；
(3) after fully being mixed by various raw materials, add vegetable oil, Adeps Sus domestica, mineral salt premix material, aminoacid premix material, vitamin premix, microelement pre-mix material, mix 10-15min；
(4) by mixed material pelletize in comminutor, diameter 3-5mm, length 8-15mm pellet is obtained。
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107259171A (en) * | 2017-07-11 | 2017-10-20 | 芜湖永昌生物科技有限公司 | A kind of biological small white mouse breeding feed |
| CN107439826A (en) * | 2017-08-31 | 2017-12-08 | 北京华阜康生物科技股份有限公司 | A kind of big mouse feed and its preparation technology for meeting GLP specifications |
| CN108850625A (en) * | 2017-06-15 | 2018-11-23 | 四川省医学科学院.四川省人民医院实验动物研究所 | Calcium deficiency type disease mouse models feed and preparation method thereof |
| CN109156608A (en) * | 2018-09-18 | 2019-01-08 | 青岛今墨堂生物技术有限公司 | A kind of experimental animal special feed and preparation method thereof |
| CN109170306A (en) * | 2018-10-26 | 2019-01-11 | 南京协同生物科学研究院有限公司 | A kind of experimental animal feed compound additive and the preparation method and application thereof |
| CN110037190A (en) * | 2019-04-18 | 2019-07-23 | 睿迪生物科技（深圳）有限公司 | A kind of big/small mouse for experiment feed and preparation method |
| CN112602852A (en) * | 2020-12-04 | 2021-04-06 | 苏州双狮实验动物饲料科技有限公司 | Irradiation mouse feed and preparation method thereof |
| CN113796468A (en) * | 2021-09-13 | 2021-12-17 | 四川省医学科学院.四川省人民医院实验动物研究所 | Rodent animal feed and preparation method thereof |
| CN114376098A (en) * | 2021-12-28 | 2022-04-22 | 苏州双狮实验动物饲料科技有限公司 | Preparation method of feed for rats and mice |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108850625A (en) * | 2017-06-15 | 2018-11-23 | 四川省医学科学院.四川省人民医院实验动物研究所 | Calcium deficiency type disease mouse models feed and preparation method thereof |
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| CN107259171A (en) * | 2017-07-11 | 2017-10-20 | 芜湖永昌生物科技有限公司 | A kind of biological small white mouse breeding feed |
| CN107439826A (en) * | 2017-08-31 | 2017-12-08 | 北京华阜康生物科技股份有限公司 | A kind of big mouse feed and its preparation technology for meeting GLP specifications |
| CN109156608A (en) * | 2018-09-18 | 2019-01-08 | 青岛今墨堂生物技术有限公司 | A kind of experimental animal special feed and preparation method thereof |
| CN109170306A (en) * | 2018-10-26 | 2019-01-11 | 南京协同生物科学研究院有限公司 | A kind of experimental animal feed compound additive and the preparation method and application thereof |
| CN110037190A (en) * | 2019-04-18 | 2019-07-23 | 睿迪生物科技（深圳）有限公司 | A kind of big/small mouse for experiment feed and preparation method |
| CN112602852A (en) * | 2020-12-04 | 2021-04-06 | 苏州双狮实验动物饲料科技有限公司 | Irradiation mouse feed and preparation method thereof |
| CN113796468A (en) * | 2021-09-13 | 2021-12-17 | 四川省医学科学院.四川省人民医院实验动物研究所 | Rodent animal feed and preparation method thereof |
| CN113796468B (en) * | 2021-09-13 | 2023-11-28 | 四川省医学科学院.四川省人民医院实验动物研究所 | Rodent feed and preparation method thereof |
| CN114376098A (en) * | 2021-12-28 | 2022-04-22 | 苏州双狮实验动物饲料科技有限公司 | Preparation method of feed for rats and mice |
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Application publication date: 20160622 |