CN105663176A - Method for preparing traditional Chinese medicine granules from puffed traditional Chinese medicine decoction pieces - Google Patents
Method for preparing traditional Chinese medicine granules from puffed traditional Chinese medicine decoction pieces Download PDFInfo
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- CN105663176A CN105663176A CN201610139169.4A CN201610139169A CN105663176A CN 105663176 A CN105663176 A CN 105663176A CN 201610139169 A CN201610139169 A CN 201610139169A CN 105663176 A CN105663176 A CN 105663176A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention provides a method for preparing traditional Chinese medicine granules from puffed traditional Chinese medicine decoction pieces.The preparation method of the puffed traditional Chinese medicine granules comprises the steps that smashing is conducted on the traditional Chinese medicine decoction pieces, and the smashing temperature is controlled according to differences of effective ingredients of the traditional Chinese medicine decoction pieces and differences of use methods; the decoction pieces with more volatile ingredients are subjected to distillation to extract essential oil, the essential oil is added to smashed granules, and the effective ingredients are subjected to replenishment; puffing treatment is conducted on the smashed decoction pieces through puffing equipment at last.Therefore, the effective ingredients of the traditional Chinese medicine granules are not lost, the solubility, disintegration, absorptivity and adhesive rate of the effective ingredients are increased, absorption of human bodies is convenient, the appearance of the decoction pieces is changed, an industrial production mode is achieved for transportation, storage and selling of the decoction pieces, and the traditional Chinese medicine storage problems such as mildew and moth and insect bites are eliminated; in addition, the clean and convenient user experience is achieved.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, in particular to a kind of method that Chinese medicinal granule prepared by expanded prepared slices of Chinese crude drugs.
Background technology
Concoct, the big gun moxibustion of ancient title, refer to the process being processed into medicine with Chinese herbal medicine raw material, have fire-making method, water method for making and water and fire a total system; Its main purpose is, by process of preparing Chinese medicine means, Chinese herbal medicine crude drug is passed through processing, strengthens medicine effect, improves clinical efficacy, eliminates toxic and side effects guarantee drug safety. Hospital's " 52 Bingfang " the earliest of China describe big gun, moxibustion, burn, forge, fritter, endure, the Chinese medicine processing method such as wine stain. Describing nearly hundred kinds of Chinese medicine processing methods in treatise on Febrile Diseases " Medical Treasures of the Golden Chamber ", during to Ming Dynasty's Chen Jia plan " book on Chinese herbal medicine covers bamboo fish trap " elaboration concocting method comprehensively, the conventional concocting method of Chinese herbal medicine is determined substantially. Forging method is to be directly placed into by medicine in smokeless stove fire or a kind of method of calcining in suitable refractory container, has and bright forges, forges and quench, vexed forge three kinds; Before application forging method carries out forging, there is a need to some medicines are carried out corresponding early stage process, as utilized steaming method to process Radix Polygoni Multiflori, Radix Scutellariae, utilize cooking method to process Radix Aconiti Radix Aconiti Kusnezoffii, utilize refining method to process Semen Persicae, Semen Armeniacae Amarum, utilize vinegar CARAPAX ET PIASTRUM TESTUDINIS PREPARATA, Carapax Trionycis etc. And during tradition forging method concocts, the effective ingredient dissolution rate of decoction pieces often higher than crude drug, this with medical material the factor such as the cell damage in concocting process, surface area increase relevant.
For improving the effective ingredient and ease of use concocting decoction pieces, along with the development of modern industrial civilization, occurred in that bulking equipment in recent years. Expanded is that machine cavity temperature raises by mechanical presses and frictional heat, and pressure increases, moisture in medicine is superheat state, when being down to low pressure by certain high pressure, and medicine internal steam instantaneous expansion, make cell wall crush, form open-textured hollow network structure. Again through controlling to pulverize temperature, granular size, humidizer soak, boil the method taken and extract, and make the dissolution rate of effective ingredient can be much better than tradition forging method. The Chinese medicines such as Ganoderma, Bulbus Fritillariae Cirrhosae, Semen Coicis, the Radix Paeoniae Alba, Rhizoma Dioscoreae, Rhizoma Drynariae, Radix Ginseng are carried out Expanded process at present, achieve good effect.The expanded promotion to nutritional labeling, is embodied in following aspect: the 1. expanded gelatinization degree improving starch, accelerates the fracture of intermolecular chain link, makes starch become simply, being more easy to the saccharide digested and assimilated. 2. expanded make lipase complete deactivation, its shelf time can be extended. Although 4. vitamin chemistry configurations, residing physics and chemical environment is quite sensitive, but in expanding processing, it is sufficiently stable for having substantial portion of vitamin, and affected degree is also very little. Such as, after Ganoderma is carried out extruding puffing, its dietary fiber occurs modified, and water solublity increases, and enhances the function of its loosening bowel to relieve constipation, invigorating the spleen and regulating the stomach, and other health cares are substantially unaffected. Visible, Ganoderma is after Expanded process, and pharmacological action is almost without change, and some drug effect becomes strong on the contrary. As can be seen here, Chinese medicine puffing technique compensate for the deficiency of tradition processing technique, is filled with new vitality for it. But the practical application of Chinese medicine puffing technique is still at an early stage at present, the expanded decoction pieces of Chinese medicine is also rarely found in our life. Progress along with science and technology, it is believed that on the basis of research at present, carries out the improvement of bulking equipment, and the expansion method that exploitation is advanced, Chinese medicine puffing technique will have very vast potential for future development.
Summary of the invention
In view of this, the present invention provides a kind of method that Chinese medicinal granule prepared by expanded prepared slices of Chinese crude drugs, this preparation method the Chinese medicinal granule effective ingredient obtained does not lose.
The preparation method of a kind of expanded Chinese medicinal granule, comprises the following steps:
The prepared slices of Chinese crude drugs are pulverized;
By size-reduced prepared slices of Chinese crude drugs humidification;
Bulking equipment is adopted to carry out expanding treatment the pulverizing decoction pieces of described humidification.
Further, described pulverizing is dry pulverization process, low temperature smashing or wall breaking pulverization.
Further, described crushing is crushed to 10～100 μm.
Further, the temperature of described low-temperature grinding is-100～0 DEG C
Further, before described humidification, also include extracting after described pulverizing;
Further, it is extracted as solvent extraction described in or vapor distillation extracts.
Further, it is extracted as described in.
Further, the drop temperature of described expanding treatment is 60～180 DEG C.
Further, described expanded discharge pressure is normal pressure.
Further, the described prepared slices of Chinese crude drugs are the flowers and plants class prepared slices of Chinese crude drugs, Rhizomatic traditional Chinese medicine decoction pieces, the fruit class prepared slices of Chinese crude drugs, the mushroom prepared slices of Chinese crude drugs or the first sheet class prepared slices of Chinese crude drugs.
Further, also include after described expanding treatment pulverizing again.
First the prepared slices of Chinese crude drugs are pulverized by the preparation method that Chinese medicinal granule prepared by the expanded prepared slices of Chinese crude drugs of the present invention; Again the prepared slices of Chinese crude drugs after smashing are extracted, obtain extracting solution; Finally adopt bulking equipment to carry out expanding treatment described extracting solution, thus make the Chinese medicinal granule effective ingredient of acquisition not lose.
Detailed description of the invention
For the ease of understanding the present invention, close embodiment below and further illustrate technical scheme.
The method that Chinese medicinal granule prepared by the expanded prepared slices of Chinese crude drugs of the present invention, comprises the following steps:
The prepared slices of Chinese crude drugs are pulverized;
By size-reduced prepared slices of Chinese crude drugs humidification;
Bulking equipment is adopted to carry out expanding treatment the pulverizing decoction pieces of described humidification
The effect of above-mentioned pulverizing is so that the volume of the prepared slices of Chinese crude drugs to be processed reduces, in order to follow-up is expanded. Pulverizing can be dry pulverization process, low temperature smashing or wall breaking pulverization.
As the instantiation of a kind of pulverizing therein, pulverizing can be dry pulverization process. Dawn known to those skilled in the art, dry pulverization process herein, pulverize also referred to as routine, mean that medicine is pulverized after suitable dried again. The equipment that dry pulverization process adopts is known equipment, for instance grinds ship, ball mill, hammer machine, Universalpulverizer etc. with ferrum and pulverizes. This method advantage is simple to operate, once becomes powder.
As the instantiation of another pulverizing, pulverizing can be low-temperature grinding. Dawn known to those skilled in the art, low-temperature grinding refers to the process that the material being cooled to brittle point temperature is broken into the less granule of particle diameter or powder body under external force herein. Low-temperature grinding can improve the efficiency of pulverizing. When raw material to be processed is fresh goods medicine, low-temperature grinding is obtained in that more prominent effect.
Low-temperature grinding can adopt Lowtemperaturepulverizer. Can listing the Lowtemperaturepulverizer of a kind of prior art therein, it is by feed bin, mechanical crusher, air-introduced machine, cyclone, vibrosieve, and liquid nitrogen container etc. forms. This Lowtemperaturepulverizer system is with liquid nitrogen for low-temperature receiver, crushed material is by after cooling down the brittle easily pulverizing state of realization at low temperatures, enter in mechanical crusher cavity by impeller high speed rotating, material and blade, fluted disc, mutual repeated stock between material and material, collision, shear, under the comprehensive functions such as friction, reach crushing effect: the material after crushed has fish grading machine of gas flow screen carry out classification and collect: the material being not reaching to fineness requirement returns feed bin continuation pulverizing, and cold air major part returns feed bin and recycles.
The temperature of aforementioned low-temperature grinding does not have strict requirement, namely lower than brittle point temperature. It is preferable, however, that the low-temperature grinding temperature of the present invention can be-100～0 DEG C, for instance-100 DEG C ,-98 DEG C ,-95 DEG C ,-90 DEG C ,-80 DEG C ,-60 DEG C ,-50 DEG C ,-30 DEG C ,-10 DEG C ,-5 DEG C or 0 DEG C etc.
Above-mentioned wall breaking pulverization refers to the jet mill of a kind of comminution by gas stream Chinese medicine, directly makes mutually to clash between medicine with powerful air-flow, allows its cell wall thoroughly crush, allows effective ingredient fully be dissolved out. Wall breaking pulverization can adopt known wall-broken grinder, and the big I as its pulverizing is 10～100 μm, for instance 10 μm, 15 μm, 20 μm, 30 μm, 50 μm, 65 μm, 80 μm, 90 μm, 95 μm, 98 μm or 100 μm etc.
The decoction pieces more for volatile ingredient may also include extraction, namely smash after, humidification before. Here, extract refer to by solvent (such as ethanol) processs, distillation, dehydration, withstanding pressure or centrifugal action, or pass through other chemically or mechanically technical process from material, produce useful component (such as constituent or juice). As the mode of the extraction of the present invention, can list one of which extraction example is solvent extraction. Solvent extraction solvent extraction method is according to composition each in Chinese herbal medicine dissolution properties in a solvent, selects active ingredient solubility, to need not the little solvent of dissolved element dissolubility, and by effective ingredient from the method being dissolved out in medical material tissue. Because the dissolubility that medicinal herb components is in a solvent is directly relevant with solvent property, and the character of each kind solvent, equally also relevant with its molecular structure. So, we just can pass through medicinal herb components structural analysis, removes to estimate the solvent of their this type of character and selection, as long as this character of the hydrophilic of medicinal herb components and lipotropy and solvent is suitable, will there is bigger dissolubility wherein, namely so-called " similar mix " rule.This is one of foundation of composition required for selection appropriate solvent extracts in Chinese herbal medicine. Known can have, as the solvent of solvent extraction, the organic solvent that ethanol, petroleum ether, ether etc. are representative. The adoptable equipment of solvent extraction is apparatus,Soxhlet's.
Also can list vapor distillation to extract as the another kind of example extracted. Extraction by steam distillation, be otherwise known as water extraction, it is adaptable to the extraction of medicinal herb components that can be not destroyed with vapor distillation. The boiling point of specific examples of such components is many more than 100 DEG C, or only slightly soluble not miscible with water, and deposits certain vapour pressure when about 100 DEG C. When heating together with water, when the vapour pressure summation of its vapour pressure and water is an atmospheric pressure, liquid begins to boiling, and volatile material is taken out of by steam in the lump. Some volatile ingredient dissolubility in water is slightly larger, often by distillate re-distillation, in the part distilled out at first, separates volatilization oil reservoir, or at distillate water layer through salting out method and with low boiling point solvent by constituents extraction out.
Aforementioned add wet process, refer to the liquid that pulverized particles adds 5～10% in mixer, for instance 5%, 5.5%, 6%, 8%, 8.5%, 9% or 10%. These liquid can be above-mentioned solvent, distilled water or oil.
Aforementioned expanding treatment, the temperature of its discharging is preferred with 60～180 DEG C, for instance 60 DEG C, 62 DEG C, 65 DEG C, 70 DEG C, 80 DEG C, 100 DEG C, 120 DEG C, 150 DEG C, 170 DEG C, 175 DEG C or 180 DEG C etc. If expanded temperature exceedes this scope, then can damage the effective active composition of medicine; On the contrary, then expanded purpose cannot be played. Noting, drop temperature expanded herein discharges the temperature of liquid by the discharging opening of bulking equipment when referring to be discharged, and now discharging liquid is spray pattern, therefore drop temperature is also referred to as atomization temperature.
Expanded pressure and time can need to do conventional selection according to the volume size of actual product granule. Here, expanded pressure refers to the pressure (high pressure) in bulking equipment and the low pressure after discharge bulking equipment, and this high pressure such as reference ground pressure is 2～9atm, low pressure can be normal pressure, i.e. 1atm, is alternatively vacuum certainly, the vacuum of such as-20～-100KPa. The expanded time is referred to be 5～40min.
Expanded equipment can adopt equipment more of the prior art, and the effect of the present invention does not rely on bulking equipment. the equipment of a kind of prior art can be listed, such as CN102727533A, particularly as follows: the double-screw type extrusion pay-off included in head and the discharge barrel coordinated with this extrusion pay-off, the exit of discharge barrel arranges the extrusion die having discharge opening, in discharge barrel, between twin-screw extrusion pay-off and extrusion die, it is provided with by-passing parts, wherein, it is provided with between twin-screw extrusion pay-off and by-passing parts with by-passing parts mutually by the tactile poly-charging tray with centre bore, the supplied materials side of by-passing parts is evenly equipped with splitter box, and splitter box converges at the blow tank of by-passing parts exit side, and blow tank is corresponding with the discharge opening of extrusion die. described splitter box is sector diffuence groove, for shunting ridge between adjacent two sector diffuence grooves, the exit side of described by-passing parts be provided centrally with central boss, the surrounding of exit side is provided with a bracer, central boss contacts with the center of extrusion die and surrounding respectively with a bracer, blow tank is centrally located between boss and a bracer, the screw rod of described double-screw type extrusion pay-off is provided with cooling structure, described cooling structure includes the blind hole concentric with screw axis offered on screw rod and the inner cool tube being provided with cooling entrance, inner cool tube stretches in described blind hole through the cooling lid closing this blind hole and its built-in length is less than blind hole depth, cooling lid has the cooling cover cavity being provided with coolant outlet, the cooling duct formed between inner cool tube with blind pore wall connects with cooling cover cavity.
The prepared slices of Chinese crude drugs that the preparation method of the present invention is targeted are relatively suitably the flowers and plants class prepared slices of Chinese crude drugs, Rhizomatic traditional Chinese medicine decoction pieces, the fruit class prepared slices of Chinese crude drugs, the mushroom prepared slices of Chinese crude drugs or the first sheet class prepared slices of Chinese crude drugs. It is easily understood that, the flowers and plants class prepared slices of Chinese crude drugs refer to flowers and plants for active constituents of medicine herein, Rhizomatic traditional Chinese medicine decoction pieces refers to rhizome for active constituents of medicine, the fruit class prepared slices of Chinese crude drugs refer to fruit or animal shell for active constituents of medicine, the mushroom prepared slices of Chinese crude drugs refer to Mycophyta Chinese medicine, first sheet class refers to that some examples that above-mentioned classification comprises are familiar with by field of Chinese medicines technical staff, do not repeat them here with fruit for active constituents of medicine.
Aforementioned expanded after also include pulverizing again. The effect pulverized again be so that expanded after the granularity of granule more conform to predetermined size. The specific implementation pulverized again can be analogous to aforementioned pulverizing before expanding treatment.
For the ease of, the preparation pulverized again can be dried. Dry mode can adopt air-dry, and air-dry temperature can be 40～50 DEG C.
Embodiment 1
First known Solvents Solvent is adopted to carry out extraction method the raw material of the flowers and fruits class prepared slices of Chinese crude drugs to be processed so that the effective ingredient in decoction pieces is precipitated out, and obtains extracting solution. Meanwhile, low-temperature grinding at the raw material of other fresh flowers fruit prepared slices of Chinese crude drugs being carried out-100 DEG C. Then, ground product is added the said extracted liquid of 5-10%, insert after mix homogeneously and bulking machine carries out expanding treatment, controlling expanded high pressure is 2～9atm, the pressure of discharging is normal pressure, the temperature controlling expanded discharging is 60 DEG C, and the expanded time is 5～40min, obtains swelling granular by screw extruding. Finally, swelling granular smashed again and be packaged to be finished particle agent.
Embodiment 2
The dry pulverization process that the raw material of Rhizomatic traditional Chinese medicine decoction pieces to be processed first utilizes " grind, shear and clash into " mode becomes powder. Then, inserting and carry out expanding treatment in bulking machine after adding pure water mix homogeneously in the ratio of 5-10%, controlling expanded high pressure is 2～9atm, the pressure of discharging is normal pressure, the temperature controlling expanded discharging is 120 DEG C, and the expanded time is 5～40min, obtains swelling granular by screw extruding. Finally, swelling granular smashed again and be packaged to be finished particle agent.
Embodiment 3
First the raw material of the fruit class prepared slices of Chinese crude drugs to be processed is carried out the forging methods such as salt stir-fry, to remove comparatively hard shell, re-use pulverizing and broken two kinds of methods are pulverized. Then, inserting and carry out expanding treatment in bulking machine after adding pure water mix homogeneously in the ratio of 5-10%, controlling expanded high pressure is 2～9atm, the pressure of discharging is normal pressure, the temperature controlling expanded discharging is 90 DEG C, and the expanded time is 5～40min, obtains swelling granular by screw extruding. Finally, swelling granular smashed again and be packaged to be finished particle agent.
Embodiment 4
First the raw material of the mushroom prepared slices of Chinese crude drugs to be processed is carried out carrying out at 0 DEG C low-temperature grinding, make mushroom decoction pieces cell wall breaking cellular wall fully in wall-broken grinder. Then, inserting and carry out expanding treatment in bulking machine after adding pure water mix homogeneously in the ratio of 5-10%, controlling expanded high pressure is 2～9atm, the pressure of discharging is normal pressure, the temperature controlling expanded discharging is 120 DEG C, and the expanded time is 5～40min, obtains swelling granular by screw extruding. Finally, swelling granular smashed again and be packaged to be finished particle agent.
Embodiment 5
First the raw material of the mushroom prepared slices of Chinese crude drugs to be processed is carried out the pretreatment of vinegar system, salt stir-fry, to reduce its toughness, then adopts the dry grinding method that " cut, grind and smash " combines to pulverize.Then, inserting and carry out expanding treatment in bulking machine after adding pure water mix homogeneously in the ratio of 5-10%, controlling expanded high pressure is 2～9atm, the pressure of discharging is normal pressure, the temperature controlling expanded discharging is 180 DEG C, and the expanded time is 5～40min, obtains swelling granular by screw extruding. Finally, swelling granular smashed again and be packaged to be finished particle agent.
We " control the part of the body cavity above the diaphragm housing the heart and lungs such as plumage according to the traditional Chinese medical science, non-gently do not lift; Control middle Jiao such as weighing apparatus, non-flat uneasiness; Control the inferior burnt such as power, non-heavy do not sink " theory, according to the characteristic that the prepared slices of Chinese crude drugs of upper, middle and lower three Jiao that divides and rules have, the expanded machine used is adjusted, to be more suitable for the expanding processing of decoction pieces. According to different clinical demands, according to different medicine attributes, it is adopted the method that different pulverizing, humidification, covering be likely to the effective ingredient lost, passing through control swelling temperature and screw extruding speed thus obtaining swelling granular, then carry out granule again pulverizing and single product packaging, obtain single product prepared slices of Chinese crude drugs of stable content.
Although puffing technique is applied relatively broad in food processing, and nearly 87 kinds of the prepared slices of Chinese crude drugs that can be used for integration of edible and medicinal herbs specified by country's " pharmacopeia " at present, and can not only make the effective ingredient of medicine not lose by the Chinese medicinal granule of the integration of edible and medicinal herbs that this method obtains, and obtain Consumer's Experience clean, convenient and good edible impression.
Chinese medicine is expanded to go to toward quality fine and close, hard, and expanded rear quality becomes loose, good looking appearance, mouthfeel be better than expanded before. The expanded rear volume increasing of Chinese medicine is twice, parenchyma cell sporoderm-broken rate, prothenchyma (of wood) partial crushing. After Chinese medicine is expanded, its decocting time shortens 70～80%, and water soluble ingredient increases by 1.9～18.4 times, and liposoluble constituent increases by 1.9～3.7 times, and therefore puffing technique accelerates the preparation production cycle and saved the energy.
It is an object of the invention to the shortcoming and defect overcoming prior art to exist, it is provided that plant medicine decoction pieces expansion method. The present invention has following advantages and good effect:
1) the prepared slices of Chinese crude drugs more standardization of this method generation, industrialization.
2) health, clean, eliminates the problems such as mould moth, insect bite, reduces the pollution in use, it is simple to shipping storage.
3) problem solving the secondary pollution in Chinese medicine concocting process and poly-doped impurity.
4) dissolubility of decoction pieces effective ingredient, disintegration, absorbance and adhesive rate are added, it is simple to the absorption of human body.
5) changing the aesthetic appearance of decoction pieces, decrease packaging and the cost of transportation of Chinese medicine decoction pieces, enhance use and property easy to carry, the experience sense improving client is subject to, and mouthfeel is better.
6) the further development and utilization to integration of edible and medicinal herbs medicine is stimulated.
Applicant states, the present invention illustrates detailed process equipment and the technological process of the present invention by above-described embodiment, but the invention is not limited in above-mentioned detailed process equipment and technological process, namely do not mean that the present invention has to rely on above-mentioned detailed process equipment and technological process could be implemented. The equivalence of each raw material of product of the present invention, it will be clearly understood that any improvement in the present invention, is replaced and the interpolation of auxiliary element, concrete way choice etc. by person of ordinary skill in the field, all falls within protection scope of the present invention and open scope.
Claims (10)
1. the method that Chinese medicinal granule prepared by expanded prepared slices of Chinese crude drugs, it is characterised in that comprise the following steps:
The prepared slices of Chinese crude drugs are pulverized;
By size-reduced prepared slices of Chinese crude drugs humidification;
Bulking equipment is adopted to carry out expanding treatment the prepared slices of Chinese crude drugs of described humidification.
2. preparation method according to claim 1, it is characterised in that the humidity of described humidification is 5～10%.
3. preparation method according to claim 1, it is characterised in that described pulverizing is dry pulverization process, low temperature smashing or wall breaking pulverization.
4. preparation method according to claim 3, it is characterised in that described crushing is crushed to 10～100 μm.
5. preparation method according to claim 1, it is characterised in that the temperature of described low-temperature grinding is-100～0 DEG C.
6. preparation method according to claim 1, it is characterised in that also include extracting before described humidification, after described pulverizing.
7. preparation method according to claim 1, it is characterised in that described in be extracted as solvent extraction or vapor distillation and extract.
8. preparation method according to claim 1, it is characterised in that the drop temperature of described expanding treatment is 60～180 DEG C.
9. preparation method according to claim 1, it is characterised in that the described prepared slices of Chinese crude drugs are the flowers and plants class prepared slices of Chinese crude drugs, Rhizomatic traditional Chinese medicine decoction pieces, the fruit class prepared slices of Chinese crude drugs, the mushroom prepared slices of Chinese crude drugs or the first sheet class prepared slices of Chinese crude drugs.
10. preparation method according to claim 1, it is characterised in that also include after described expanding treatment pulverizing again.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111035657A (en) * | 2020-01-22 | 2020-04-21 | 芜湖张恒春药业有限公司 | Processing method of tortoise |
| CN113875888A (en) * | 2021-10-20 | 2022-01-04 | 河南神农膨化饲料科技有限公司 | Preparation method of puffed traditional Chinese medicine feed additive and additive thereof |
| CN115211492A (en) * | 2022-06-07 | 2022-10-21 | 圣道生物技术(山东)有限公司 | Stress relieving medicine for resisting stress and promoting growth of livestock and poultry and preparation method and application thereof |
| CN115381105A (en) * | 2022-08-02 | 2022-11-25 | 浙江莫干湖健康科技有限公司 | Low-sugar functional food with peptide as raw material and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1111997A (en) * | 1994-05-19 | 1995-11-22 | 王滨鸿 | Method for bulking Chinese medicinal herbs |
| CN1557186A (en) * | 2004-01-13 | 2004-12-29 | 金英珠 | Black edible fungus, sesame dilated food and its making method |
-
2016
- 2016-03-11 CN CN201610139169.4A patent/CN105663176A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1111997A (en) * | 1994-05-19 | 1995-11-22 | 王滨鸿 | Method for bulking Chinese medicinal herbs |
| CN1557186A (en) * | 2004-01-13 | 2004-12-29 | 金英珠 | Black edible fungus, sesame dilated food and its making method |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111035657A (en) * | 2020-01-22 | 2020-04-21 | 芜湖张恒春药业有限公司 | Processing method of tortoise |
| CN113875888A (en) * | 2021-10-20 | 2022-01-04 | 河南神农膨化饲料科技有限公司 | Preparation method of puffed traditional Chinese medicine feed additive and additive thereof |
| CN115211492A (en) * | 2022-06-07 | 2022-10-21 | 圣道生物技术(山东)有限公司 | Stress relieving medicine for resisting stress and promoting growth of livestock and poultry and preparation method and application thereof |
| CN115211492B (en) * | 2022-06-07 | 2024-04-19 | 圣道生物技术(山东)有限公司 | Stress-resistant growth-promoting stress-relieving medicine for livestock and poultry, and preparation method and application thereof |
| CN115381105A (en) * | 2022-08-02 | 2022-11-25 | 浙江莫干湖健康科技有限公司 | Low-sugar functional food with peptide as raw material and preparation method thereof |
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