CN105661392A - Qinghai cherokee rose fruit-fructus hippophae-Nitraria sibirica Pall fruit powder compound as well as tablet and application thereof - Google Patents
Qinghai cherokee rose fruit-fructus hippophae-Nitraria sibirica Pall fruit powder compound as well as tablet and application thereof Download PDFInfo
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- 150000001875 compounds Chemical class 0.000 title claims abstract description 22
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention provides a Qinghai cherokee rose fruit-fructus hippophae-Nitraria sibirica Pall fruit powder compound as well as tablets and an application thereof. The Qinghai cherokee rose fruit-fructus hippophae-Nitraria sibirica Pall fruit powder compound is prepared from the following raw materials in parts by weight: 1-5 parts of cherokee rose fruit powder, 1-2 parts of fructus hippophae powder and 1-10 parts of Nitraria sibirica Pall fruit powder. Experiments of the invention have proved that powder compounds of highland berries of a great number of proportions are similar in anti-oxidation effects; however, the proportion of '4 parts of cherokee rose fruit powder, 1 part of fructus hippophae powder and 5 parts of Nitraria sibirica Pall fruit powder' has an anti-oxidation activity which is obviously better than the anti-oxidation activities of the other proportions; and the proportion is especially outstanding in anti-superoxide anion radical effects. Therefore, the proportion of '4 parts of cherokee rose fruit powder, 1 part of fructus hippophae powder and 5 parts of Nitraria sibirica Pall fruit powder' is the preferable proportion of the invention; and the anti-superoxide anion radical effect of the proportion is the preferable application of the invention.
Description
Technical field
The invention belongs to field of health care products, be specifically related to a kind of yellow thorn, Fructus Hippophae, Nitraria tangutorum fruit compound powder and tablet thereof and purposes.
Technical background
Quickening along with modern life rhythm, the aggravation of social competition, the muscle power of people, the tired long term accumulation such as mental, psychological, the factors such as diet is unhealthy in addition, environmental radiation increases, cause that people's interior free yl is too much, make increasing people be in " subhealth state " state. Free radical is a kind of asymmetric, unstable atom because losing an electronics or molecule, has very big energy. Free radical always attempts to capture an electronics to reach new balance, and for materials such as the lipid in this its meeting attack cells tissue, protein, saccharide and DNA, this has resulted in the oxidative damage etc. of the inactivation of anaenzyme of the peroxidating of lipid, protein, DNA. Additionally, when people's fatigue, internal meeting creates substantial amounts of metabolite, such as lactic acid, carbon dioxide, serum urea nitrogen etc., this kind of material gathers in vivo, stimulates human tissue cell and nervous system. Health is chronically at fatigue state, can cause the adverse consequencess such as hormone in vivo Metabolic disorder, nervous system regulatory function exception, hypoimmunity.
Cortex Acanthopanacis Radicis (Nitraria) is zygophyllaceae (Zygophyllceae) plant, be grown in height above sea level more than 3000 meters Gobi Desert Terrain area mainly build one of mass-planting thing. Its strong stress resistance, drought-resistant saline and alkaline, it is excellent shrub of checking winds and fixing drifting sand. Cortex Acanthopanacis Radicis ripe berry is aubergine, nontoxic edible, and its fruit Middle nutrition composition and medicines and health protection active component kind are many, rich content. Seed oil is mainly composed of the unsaturated fatty acids such as linoleic acid, linolenic acid, arachidonic acid, and wherein linoleic content is up to 70%, really belongs to exception in plant kingdom. And the existing bibliographical information of effect of its resisting fatigue, it has and reduces after motion the function of lactic acid and blood urea nitrogen in Mice Body.
Fructus Hippophae is Elaeangnaceae hippophae plant (Hippophaerhamnoides), and it has another name called acid thorn, vinegar willow, black thorn. Fructus Hippophae all has widely distributed in the northern and southwestern multiple provinces and regions of China, and its growth height above sea level is between 1000-4500 rice, and its plant also has significantly high Ecological Information and is worth. Its fruit is sour-sweet, nutritious, and pharmaceutical applications is worth greatly, has developed application to multiple products.The elite of its fruit is in that its seed oil. Existing many parts of reports are verified, and its seed oil also has vitamins, Polyphenols, fatty acid, waits various bioactivators, and more than its contained vitamin kind, the abundant any fruit and vegerable of content can not be compared, and therefore, is described as " vitamin treasure-house ". Meanwhile, scholar's research is also had to show, and other area plantation Fructus Hippophae ratios, the Vitamin C content in the sea buckthorn fruit of Qinghai-Tibet Platean is higher than other low altitude areas 2 times more than.
Yellow thorn, the straight fringe Radix Berberidis Amurensis BerberisdasystachyaMaxim. of Berberidaceae plant, it is for ethnic groups such as illiteracy, Tibetan, Uygur medicinal with edible traditional wild acinus the same as Cortex Acanthopanacis Radicis, Fructus Hippophae (black thorn), is referred to as " Qinghai three is stung ". Containing the neutraceutical active ingredients that abundant vitamin, aminoacid, polysaccharide etc. are abundant during yellow bur is real. Straight fringe Radix Berberidis Amurensis fruit medicine function has been done brief description in " hiding book on Chinese herbal medicine " by " hiding mark ", and it has the functions such as treatment stomachache, dyspepsia, abdominal distention, dysentery. Yellow thorn seed accounts for the 41-46% of yellow thorn mature fruit gross mass, and it is grease-contained is mainly composed of unsaturated fatty acid, and the content such as linoleic acid plus linolenic acid just account for nearly 60%, has high nutrition and medical value.
Summary of the invention
It is an object of the invention to provide a kind of based on Huang thorn, Fructus Hippophae, Nitraria tangutorum fruit compound powder and tablet. Another object of the present invention is to provide the purposes of said composition or tablet.
Specifically, the invention provides a kind of Qinghai three bur compound powder, it is prepared by the raw material composition of weight proportion:
Yellow 1～5 part of bur powder, seabuckthorn fruit powder 1～2 part, 1～10 part of Fructus Nitraria schoberi powder.
Preferably, it is prepared by the raw material composition of weight proportion:
Yellow 4 parts of bur powder, seabuckthorn fruit powder 1 part, 5 parts of Fructus Nitraria schoberi powder.
Wherein, described yellow bur powder, seabuckthorn fruit powder, Fructus Nitraria schoberi powder are prepared by one of method and prepare:
Method one: take yellow thorn, Fructus Hippophae or Nitraria tangutorum fruit, after drying, be crushed to 600～800 orders, obtain yellow bur powder, seabuckthorn fruit powder or Fructus Nitraria schoberi powder;
Method two: take yellow thorn, Fructus Hippophae or Nitraria tangutorum fruit, squeeze the juice, filter, after fruit juice spray drying, obtain yellow bur powder, seabuckthorn fruit powder or Fructus Nitraria schoberi powder;
Method three: take yellow thorn, Fructus Hippophae or Nitraria tangutorum fruit, extract for solvent with water, after extracting solution spray drying, obtain yellow bur powder, seabuckthorn fruit powder or Fructus Nitraria schoberi powder.
Present invention also offers a kind of Qinghai three bur powder tablet, it is with above-mentioned Qinghai three bur compound powder for active component, also comprises adjuvant conventional on tablet.
Further, described Qinghai three bur compound powder accounts for the 10～45% of tablet gross mass.
Further, the supplementary material weight proportion of described tablet is as follows:
Described Qinghai three bur compound powder 10～45 parts, starch 10～40 parts, microcrystalline Cellulose 10～25 parts, sucrose 10～18 parts, 0.4～1 part of sodium chloride, PEG60002～4 part;
Preferably, state Qinghai three bur compound powder to be made up of the raw material of following weight proportion: yellow 4 parts of bur powder, seabuckthorn fruit powder 1 part, 5 parts of Fructus Nitraria schoberi powder.
Tablet of the present invention, it is possible to be chewable tablet.
Present invention also offers the purposes that above-mentioned composition or above-mentioned tablet possess in the food of anti-oxidation efficacy, health product or medicine in preparation.
Further, described food, health product or medicine are to remove ABTS free radical, ultra-oxygen anion free radical or the food of hydroxy radical, health product or medicine.
Preferably, described food, health product or medicine are to remove the food of ultra-oxygen anion free radical, health product or medicine.
The present invention studies discovery, and berry mixing fruit powder in plateau has good anti-oxidation function, can notable anti-hydroxy radical/ultra-oxygen anion free radical, and ABTS free radical.
The present invention also finds in an experiment, plateau berry fruit compound powder is under most proportionings, its antioxidation is similar, but, under " yellow 4 parts of bur powder, seabuckthorn fruit powder 1 part, 5 parts of Fructus Nitraria schoberi powder " this proportioning, the antioxidant activity of compositions is substantially better than other each group, particularly the performance on superoxide anion resisitance free radical is especially prominent, therefore, said ratio is as the optimum ratio of the present invention, and the effect of its antagonism ultra-oxygen anion free radical can as the preferable use of the present invention; Meanwhile, the antioxidant activity of above-mentioned optimum proportioning is also significantly better than each single fruit powder. Above-mentioned experiment conclusion suffices to show that, 3 kinds of fruit powder under specific consumption proportion, have been played synergistic function by the present invention.
It addition, fruit powder specific surface area is excessive, it is easy to moisture absorption, should not store, and be not easy to plug and play. In view of the foregoing, Huang thorn, Fructus Hippophae, Nitraria tangutorum fruit powder are prepared into tablet by the present invention, are namely easy to the storage of product, transport and packaging, also allow for various people simultaneously and use.
Detailed description of the invention
The preparation of embodiment 1 present composition
Take yellow thorn, Fructus Hippophae or Nitraria tangutorum fruit respectively, after drying, be crushed to 600～800 orders, obtain Chinese wolfberry fruit powder, yellow bur powder, seabuckthorn fruit powder or Fructus Nitraria schoberi powder.
Each fruit powder is carried out proportioning mixing with yellow 4 parts of bur powder, seabuckthorn fruit powder 1 part, 5 parts of Fructus Nitraria schoberi powder, obtains the present composition.
The preparation of embodiment 2 Tablets
Table 1
| Plateau berry composition | Group 1 | Group 2 | Group 3 |
| Yellow bur powder | 16% | 12% | 8% |
| Seabuckthorn fruit powder | 4% | 3% | 2% |
| Fructus Nitraria schoberi powder | 20% | 15% | 10% |
| Microcrystalline Cellulose 10%～25% | 20% | 25% | 27% |
| Starch 10～40% | 25% | 25% | 30% |
| Sucrose 10～18% | 10% | 15% | 18% |
| Sodium chloride 0.4～1% | 1% | 1% | 1% |
| PEG60002～4% | 4% | 4% | 4% |
Antioxidation activity in vitro is tested
(1) material: berry fruit powder is stung in Qinghai three: for micronizing gained fruit powder, prepares with reference to the embodiment of the present invention 1, and respectively really powder combination matching is referring to table 2.
(2) experimental apparatus and reagent: TGL-16G-A type tube centrifuge, Anting Scientific Instrument Factory, Shanghai; UV-722N visible ultraviolet spectrophotometer, Shanghai Ni Ke company limited; HD type thermostat water bath, Constant Temp. Instrument Factory, Liaoyang. DPPH, ABTS are purchased from Shanghai Jing Chun biochemical technology limited company (Aladdin); The reagent such as potassium peroxydisulfate, sodium dihydrogen phosphate, disodium hydrogen phosphate, sodium chloride, trichloroacetic acid are all purchased from Shandong YuWang Industry Co., Ltd; Superoxide anion test kit, hydroxy radical test kit are all purchased from Nanjing and build up bio tech ltd.
(3) ABTS Scavenging activity: ABTS dissolving (+H2O) to final concentration of 7mmol/L, potassium peroxydisulfate is configured to 2.45mmol/L, is mixed by the two solution, is positioned over dark, stirs 16h under room temperature condition; It is 0.70 ± 0.02 that ABTS mixed solution PBS solution (PH=7.0) is then diluted to its light absorption value (surveying in 734nm place); The mixing suspension being made into final concentration of 16mg/mL by required weight ratio after berry fruit powder weighs up with distilled water is stung in Qinghai three;Finally joining in ABTS mixed solution by the sample of above-mentioned concentration, its sample and ABTS mixed solution ratio are 1: 20, in incubated at room temperature 6min after mixing, measure light absorption value in 734nm place.
Computing formula: ABTS clearance rate (%)=(1-Asample/Acontrol) × 100%
Wherein AcontrolLight absorption value for ABTS mixed solution; AsampleFor the light absorption value measured after adding sample in ABTS mixed solution.
(4) ultra-oxygen anion free radical Scavenging activity and hydroxy radical all adopt Nanjing to build up test kit detection. Wherein, the mixing suspension being made into final concentration of 16mg/mL by required weight ratio after berry fruit powder weighs up with distilled water is stung in Qinghai three.
Table 2
The present invention finds in previous experiments, according to fruit compound powder prepared by the front 4 kinds of proportionings in table 2, is respectively provided with good antioxidant activity, and each group activity is comparatively similar, wherein better with the 1st group of proportioning; But inventors discovered unexpectedly that, when fruit compound powder proportioning is " yellow 4 parts of bur powder, seabuckthorn fruit powder 1 part, 5 parts of Fructus Nitraria schoberi powder ", the antioxidant activity of compositions is significantly improved, and particularly the ability of superoxide anion resisitance free radical improves especially pronounced, therefore the present invention preferably this proportioning; Meanwhile, the antioxidant activity of above-mentioned optimum proportioning is also significantly better than each single fruit powder. Above-mentioned experiment conclusion suffices to show that, 3 kinds of fruit powder under specific consumption proportion, have been played synergistic function by the present invention.
Claims (10)
1. a Qinghai three bur compound powder, it is characterised in that: it is prepared by the raw material composition of weight proportion:
Yellow 1～5 part of bur powder, seabuckthorn fruit powder 1～2 part, 1～10 part of Fructus Nitraria schoberi powder.
2. Qinghai three according to claim 1 bur compound powder, it is characterised in that: it is prepared by the raw material composition of weight proportion:
Yellow 4 parts of bur powder, seabuckthorn fruit powder 1 part, 5 parts of Fructus Nitraria schoberi powder.
3. Qinghai three according to claim 1 and 2 bur compound powder, it is characterised in that: described yellow bur powder, seabuckthorn fruit powder, Fructus Nitraria schoberi powder are prepared by one of method and prepare:
Method one: take yellow thorn, Fructus Hippophae or Nitraria tangutorum fruit, after drying, be crushed to 600～800 orders, obtain yellow bur powder, seabuckthorn fruit powder or Fructus Nitraria schoberi powder;
Method two: take yellow thorn, Fructus Hippophae or Nitraria tangutorum fruit, squeeze the juice, filter, after fruit juice spray drying, obtain yellow bur powder, seabuckthorn fruit powder or Fructus Nitraria schoberi powder;
Method three: take yellow thorn, Fructus Hippophae or Nitraria tangutorum fruit, extract for solvent with water, after extracting solution spray drying, obtain yellow bur powder, seabuckthorn fruit powder or Fructus Nitraria schoberi powder.
4. a Qinghai three bur powder tablet, it is characterised in that: it is with Qinghai described in claims 1 to 3 three bur compound powder for active component, also comprises adjuvant conventional on tablet.
5. Qinghai three according to claim 4 bur powder tablet, it is characterised in that: described in described claims 1 to 3, Qinghai three bur compound powder accounts for the 10～45% of tablet gross mass.
6. Qinghai three according to claim 5 bur powder tablet, it is characterised in that: the supplementary material weight proportion of described tablet is as follows:
Described Qinghai three bur compound powder 10～45 parts, starch 10～40 parts, microcrystalline Cellulose 10～25 parts, sucrose 10～18 parts, 0.4～1 part of sodium chloride, PEG60002～4 part.
7. plateau according to claim 6 berry tablet, it is characterised in that: described Qinghai three bur compound powder is made up of the raw material of following weight proportion: yellow 4 parts of bur powder, seabuckthorn fruit powder 1 part, 5 parts of Fructus Nitraria schoberi powder.
8. compositions described in claims 1 to 3 or tablet described in claim 4～7 possess the purposes in the food of anti-oxidation efficacy, health product or medicine in preparation.
9. purposes according to claim 8, it is characterised in that: described food, health product or medicine are to remove ABTS free radical, ultra-oxygen anion free radical or the food of hydroxy radical, health product or medicine.
10. purposes according to claim 9, it is characterised in that: described food, health product or medicine are to remove the food of ultra-oxygen anion free radical, health product or medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511010143.1A CN105661392A (en) | 2015-12-18 | 2015-12-18 | Qinghai cherokee rose fruit-fructus hippophae-Nitraria sibirica Pall fruit powder compound as well as tablet and application thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511010143.1A CN105661392A (en) | 2015-12-18 | 2015-12-18 | Qinghai cherokee rose fruit-fructus hippophae-Nitraria sibirica Pall fruit powder compound as well as tablet and application thereof |
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| CN105661392A true CN105661392A (en) | 2016-06-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201511010143.1A Pending CN105661392A (en) | 2015-12-18 | 2015-12-18 | Qinghai cherokee rose fruit-fructus hippophae-Nitraria sibirica Pall fruit powder compound as well as tablet and application thereof |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1260147A (en) * | 1999-09-20 | 2000-07-19 | 青海省青藏高原生物制品有限公司 | Wolfberry fruit juice beverage |
-
2015
- 2015-12-18 CN CN201511010143.1A patent/CN105661392A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1260147A (en) * | 1999-09-20 | 2000-07-19 | 青海省青藏高原生物制品有限公司 | Wolfberry fruit juice beverage |
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