CN105660887A - Corn oil blending oil containing folate liposomes and preparation method thereof - Google Patents
Corn oil blending oil containing folate liposomes and preparation method thereof Download PDFInfo
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- CN105660887A CN105660887A CN201610030399.7A CN201610030399A CN105660887A CN 105660887 A CN105660887 A CN 105660887A CN 201610030399 A CN201610030399 A CN 201610030399A CN 105660887 A CN105660887 A CN 105660887A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/02—Other edible oils or fats, e.g. shortenings, cooking oils characterised by the production or working-up
- A23D9/04—Working-up
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Abstract
The invention discloses a corn oil blending oil containing folate liposomes and a preparation method thereof. The corn oil blending oil comprises corn oil, sunflower oil, walnut oil, folate liposomes, tert-butylhydroquinone, and a compound synergist; the weight percentages of corn oil, sunflower oil and walnut oil are as follows: 45-55%, 15-23%, and 28-35%; addition of folate liposomes is 0.02-0.04% of the sum of weights of the corn oil, the sunflower oil and the walnut oil; addition of tert-butylhydroquinone is 0.019% of the sum of weights of the corn oil, the sunflower oil and the walnut oil; and addition of the compound synergist is 0.021% of the sum of weights of the corn oil, the sunflower oil and the walnut oil. The method concretely comprises the following steps: a first step: preparation of folate liposomes; and a second step: preparation of the blending oil. The blending oil has the beneficial effects that the folate liposomes are fully dissolved in the blending edible oil which is prepared by the corn oil, the walnut oil and the sunflower oil, and foodstuff meets folate demands of female who is prepared for pregnancy and is in the period of pregnancy.
Description
Technical field
The present invention relates to a kind of Semen Maydis oil mixed oil and preparation method, particularly to a kind of Semen Maydis oil mixed oil containing folic acid liposome and preparation method.
Background technology
Folic acid is the water-soluble B vitamin of needed by human, and health is played an important role. The shortage of folic acid can cause that human erythrocyte and hematopoietic stem cell are abnormal, causes megaloblastic anemia. The intake of period of gestation folic acid is not enough, and fetus is it is possible that neurocele developmental defect and teratogenesis, and the formation of Placenta Hominis and growth can be influenced by impact thus causing fetal intrauterine growth retardation and premature labor. Therefore preparing women and the women of period of gestation of pregnancy, every day, folic acid dose must reach 400 μ g, supplements as early as possible and can effectively reduce following baby and the probability of deformity occur. It is the unique channel that human body obtains folic acid from external world's absorption. Although containing folic acid in many foods, but its character is unstable and easy in inactivation, really be able to be absorbed by the body the amount utilized being insufficient to. Folic acid liposome makes folic acid be dissolved in edible oil on the basis of the maintenance original nutritive value of folic acid, it is possible to supplement sufficient folic acid from diet; Meanwhile, the functional mixed oil of large-scale production is possible not only to meet the market demand, expand enterprise market, especially one of guarantee of anemia of pregnant woman and foetus health, progressively makes up the shortcoming of YESUAN PIAN on market. Better incorporate mixed oil balanced in nutrition after folic acid hydrated lipidic body, it is ensured that while folic acid envelop rate, also ensure that its nutritive value is unaffected, promote the absorption of human body. Therefore, homofolic acid mixed oil has huge advantage compared with the common edible oil in market, meets the future market demand to functionalization.
Summary of the invention
The invention aims to solve women in a kind of Semen Maydis oil mixed oil containing folic acid liposome preparing that the demand of folic acid provides by conceived and period of gestation and preparation method.
Semen Maydis oil mixed oil containing folic acid liposome provided by the invention includes Semen Maydis oil, Oleum Helianthi, walnut oil, folic acid liposome, butylhydroquinone and composite synergist, wherein Semen Maydis oil, percentage by weight shared by Oleum Helianthi and walnut oil is 45-55%, 15-23% and 28-35%, the addition of folic acid liposome is Semen Maydis oil, the 0.02-0.04% of Oleum Helianthi and walnut oil weight sum, the addition of butylhydroquinone is Semen Maydis oil, the 0.019% of Oleum Helianthi and walnut oil weight sum, the addition of composite synergist is Semen Maydis oil, the 0.021% of Oleum Helianthi and walnut oil weight sum.
Composite synergist is made up of citric acid and vitamin C, is 3:2 by weight citric acid and ascorbic mixed proportion.
The preparation method of the Semen Maydis oil mixed oil containing folic acid liposome provided by the invention, its concrete grammar is as described below:
The first step, folic acid liposome preparation:
1), measure hydrogenated soya phosphatide by weight 2.15-2.65:1 to mix with cholesterol, being subsequently adding trainingization PHOSPHATIDYL ETHANOLAMINE to carry out being sufficiently mixed uniformly, the weight ratio of trainingization PHOSPHATIDYL ETHANOLAMINE and hydrogenated soya phosphatide and cholesterol sum is 1:3.20-3.85;
2), take chloroform by 1) in mixture fully vibrate dissolving, ultrasonic 20-30s makes solution mix homogeneously;
3), use Rotary Evaporators to remove 2) in the organic solvent of mixed liquor, rotate at 40 DEG C and be evaporated up on wall to form faint yellow or transparent liposome membrane; At 62 DEG C, logical pure nitrogen gas continues dry 12h removing residual organic solvent;
4) the 0.3moL/L folic acid solution hydration 3 that, enchashment is joined) in dried liposome, the mixed proportion of folic acid solution and liposome is 300 μ L:1.758-2.139mg, the pH value of mixed liquor is 6.45-7, after the folic acid solution adding liposome is vibrated, it is positioned in the incubator of 50-55 DEG C 25-30min, makes it fully dissolve mixed liquor vibration every 5min; Then by the mixed liquor Ultrasonic Pulverization 3-5min of folic acid hydrated lipidic body; Mixed liquor after ultrasonic is loaded in 1mL syringe, releases 3-5 time from the polycarbonate membrane of 100nm, it is thus achieved that folic acid liposome, be saved in 4 DEG C of refrigerators;
Second step, mixed oil preparation:
1), by weight percentage 45-55%, 15-23% and 28-35% take Semen Maydis oil, Oleum Helianthi and walnut oil respectively and be sufficiently mixed, at 20 DEG C, stir 30min;
2), in 1) in the ratio of percentage by weight 0.02-0.04% of mixed oil take the folic acid liposome prepared in the first step and add in mixed oil after stirring 5min, by ultrasonic for mixed oil 15min, it is stirred 1min at interval of 5min, enables folic acid liposome to be uniformly distributed in mixed oil;
3), by 1) in the percentage by weight 0.019%, 0.021% of mixed oil respectively to 2) in the mixed oil for preparing adds butylhydroquinone and composite synergist continuously stirred 30min again, the mixed oil of mix homogeneously is loaded in aseptic tank, preserve under 20 DEG C of shady and cool conditions.
Hyperacoustic power of the ultrasonic use in above-mentioned steps is 380W, ultrasonic 3-5min when supersonic frequency is ultrasonic 30s interval 10s.
Beneficial effects of the present invention:
Mixed oil provided by the invention is the blending edible oil using Semen Maydis oil, walnut oil and Oleum Helianthi preparation, make the ratio optimization of all kinds of fatty acids in edible oil, the human body demand percentage to fatty acid can be more conformed to, and folic acid liposome is substantially soluble in aforesaid mixed oil, releases and meet women at preparation pregnancy and the period of gestation functional food to folic acid demand.
The present invention adopts membrane-sonic method to prepare folic acid liposome, hydrogenated soya phosphatide, cholesterol and training PHOSPHATIDYL ETHANOLAMINE is used to carry out folic acid liposomal preparation, the combination of three is effectively increased the envelop rate of folic acid liposome, make structure more tight, strengthen the stability of folic acid liposome.
Citric acid and vitamin C are acknowledged as the antioxidant of excellent. The present invention will in combination with being configured to composite synergist, and both are collaborative can better play antioxidation, increases the stability of edible oil, extends the shelf life, and ensures the balance of each fatty acid proportion in oil.
By ultrasonic applications in prepared by folic acid liposomal preparation and folic acid mixed oil, promote emulsifying, make solution more uniform, stable. The present invention introduces ultrasound wave and promotes the ability of folic acid hydrated lipidic body, improves envelop rate, also makes that folic acid liposome is evenly stable to be present in Semen Maydis mixed oil.
Detailed description of the invention
Embodiment one:
Semen Maydis oil mixed oil containing folic acid liposome provided by the invention includes Semen Maydis oil, Oleum Helianthi, walnut oil, folic acid liposome, butylhydroquinone and composite synergist, wherein Semen Maydis oil, percentage by weight shared by Oleum Helianthi and walnut oil is 45%, 23% and 32%, the addition of folic acid liposome is Semen Maydis oil, the 0.02% of Oleum Helianthi and walnut oil weight sum, the addition of butylhydroquinone is Semen Maydis oil, the 0.019% of Oleum Helianthi and walnut oil weight sum, the addition of composite synergist is Semen Maydis oil, the 0.021% of Oleum Helianthi and walnut oil weight sum.
Composite synergist is made up of citric acid and vitamin C, is 3:2 by weight citric acid and ascorbic mixed proportion.
The preparation method of the Semen Maydis oil mixed oil containing folic acid liposome provided by the invention, its concrete grammar is as described below:
The first step, folic acid liposome preparation:
1), measuring hydrogenated soya phosphatide mix with cholesterol by weight 2.15:1, be subsequently adding trainingization PHOSPHATIDYL ETHANOLAMINE and carry out being sufficiently mixed uniform, the weight ratio of trainingization PHOSPHATIDYL ETHANOLAMINE and hydrogenated soya phosphatide and cholesterol sum is 1:3.20;
2), take chloroform by 1) in mixture fully vibrate dissolving, ultrasonic 20-30s makes solution mix homogeneously;
3), use Rotary Evaporators to remove 2) in the organic solvent of mixed liquor, rotate at 40 DEG C and be evaporated up on wall to form faint yellow or transparent liposome membrane; At 62 DEG C, logical pure nitrogen gas continues dry 12h removing residual organic solvent;
4) the 0.3moL/L folic acid solution hydration 3 that, enchashment is joined) in dried liposome, the mixed proportion of folic acid solution and liposome is 300 μ L:1.758mg, the pH value of mixed liquor is 6.5, after the folic acid solution adding liposome is vibrated, it is positioned in the incubator of 50-55 DEG C 25-30min, makes it fully dissolve mixed liquor vibration every 5min; Then by the mixed liquor Ultrasonic Pulverization 3-5min of folic acid hydrated lipidic body; Mixed liquor after ultrasonic is loaded in 1mL syringe, releases 3-5 time from the polycarbonate membrane of 100nm, it is thus achieved that folic acid liposome, be saved in 4 DEG C of refrigerators;
Second step, mixed oil preparation:
1), 45%, 23% and 32% take Semen Maydis oil, Oleum Helianthi and walnut oil respectively and be sufficiently mixed by weight percentage, at 20 DEG C, stir 30min;
2), in 1) in the ratio of percentage by weight 0.02% of mixed oil take the folic acid liposome prepared in the first step and add in mixed oil after stirring 5min, by ultrasonic for mixed oil 15min, it is stirred 1min at interval of 5min, enables folic acid liposome to be uniformly distributed in mixed oil;
3), by 1) in the percentage by weight 0.019%, 0.021% of mixed oil respectively to 2) in the mixed oil for preparing adds butylhydroquinone and composite synergist continuously stirred 30min again, the mixed oil of mix homogeneously is loaded in aseptic tank, preserve under 20 DEG C of shady and cool conditions.
Hyperacoustic power of the ultrasonic use in above-mentioned steps is 380W, ultrasonic 3-5min when supersonic frequency is ultrasonic 30s interval 10s.
Embodiment two:
Semen Maydis oil mixed oil containing folic acid liposome provided by the invention includes Semen Maydis oil, Oleum Helianthi, walnut oil, folic acid liposome, butylhydroquinone and composite synergist, wherein Semen Maydis oil, percentage by weight shared by Oleum Helianthi and walnut oil is 55%, 15% and 30%, the addition of folic acid liposome is Semen Maydis oil, the 0.04% of Oleum Helianthi and walnut oil weight sum, the addition of butylhydroquinone is Semen Maydis oil, the 0.019% of Oleum Helianthi and walnut oil weight sum, the addition of composite synergist is Semen Maydis oil, the 0.021% of Oleum Helianthi and walnut oil weight sum.
Composite synergist is made up of citric acid and vitamin C, is 3:2 by weight citric acid and ascorbic mixed proportion.
The preparation method of the Semen Maydis oil mixed oil containing folic acid liposome provided by the invention, its concrete grammar is as described below:
The first step, folic acid liposome preparation:
1), measuring hydrogenated soya phosphatide mix with cholesterol by weight 2.65:1, be subsequently adding trainingization PHOSPHATIDYL ETHANOLAMINE and carry out being sufficiently mixed uniform, the weight ratio of trainingization PHOSPHATIDYL ETHANOLAMINE and hydrogenated soya phosphatide and cholesterol sum is 1:3.85;
2), take chloroform by 1) in mixture fully vibrate dissolving, ultrasonic 20-30s makes solution mix homogeneously;
3), use Rotary Evaporators to remove 2) in the organic solvent of mixed liquor, rotate at 40 DEG C and be evaporated up on wall to form faint yellow or transparent liposome membrane; At 62 DEG C, logical pure nitrogen gas continues dry 12h removing residual organic solvent;
4) the 0.3moL/L folic acid solution hydration 3 that, enchashment is joined) in dried liposome, the mixed proportion of folic acid solution and liposome is 300 μ L:2.139mg, the pH value of mixed liquor is 7, after the folic acid solution adding liposome is vibrated, it is positioned in the incubator of 50-55 DEG C 25-30min, makes it fully dissolve mixed liquor vibration every 5min; Then by the mixed liquor Ultrasonic Pulverization 3-5min of folic acid hydrated lipidic body; Mixed liquor after ultrasonic is loaded in 1mL syringe, releases 3-5 time from the polycarbonate membrane of 100nm, it is thus achieved that folic acid liposome, be saved in 4 DEG C of refrigerators;
Second step, mixed oil preparation:
1), 55%, 15% and 30% take Semen Maydis oil, Oleum Helianthi and walnut oil respectively and be sufficiently mixed by weight percentage, at 20 DEG C, stir 30min;
2), in 1) in the ratio of percentage by weight 0.04% of mixed oil take the folic acid liposome prepared in the first step and add in mixed oil after stirring 5min, by ultrasonic for mixed oil 15min, it is stirred 1min at interval of 5min, enables folic acid liposome to be uniformly distributed in mixed oil;
3), by 1) in the percentage by weight 0.019%, 0.021% of mixed oil respectively to 2) in the mixed oil for preparing adds butylhydroquinone and composite synergist continuously stirred 30min again, the mixed oil of mix homogeneously is loaded in aseptic tank, preserve under 20 DEG C of shady and cool conditions.
Hyperacoustic power of the ultrasonic use in above-mentioned steps is 380W, ultrasonic 3-5min when supersonic frequency is ultrasonic 30s interval 10s.
Embodiment three:
Semen Maydis oil mixed oil containing folic acid liposome provided by the invention includes Semen Maydis oil, Oleum Helianthi, walnut oil, folic acid liposome, butylhydroquinone and composite synergist, wherein Semen Maydis oil, percentage by weight shared by Oleum Helianthi and walnut oil is 50%, 15% and 35%, the addition of folic acid liposome is Semen Maydis oil, the 0.03% of Oleum Helianthi and walnut oil weight sum, the addition of butylhydroquinone is Semen Maydis oil, the 0.019% of Oleum Helianthi and walnut oil weight sum, the addition of composite synergist is Semen Maydis oil, the 0.021% of Oleum Helianthi and walnut oil weight sum.
Composite synergist is made up of citric acid and vitamin C, is 3:2 by weight citric acid and ascorbic mixed proportion.
The preparation method of the Semen Maydis oil mixed oil containing folic acid liposome provided by the invention, its concrete grammar is as described below:
The first step, folic acid liposome preparation:
1), measuring hydrogenated soya phosphatide mix with cholesterol by weight 2.4:1, be subsequently adding trainingization PHOSPHATIDYL ETHANOLAMINE and carry out being sufficiently mixed uniform, the weight ratio of trainingization PHOSPHATIDYL ETHANOLAMINE and hydrogenated soya phosphatide and cholesterol sum is 1:3.5;
2), take chloroform by 1) in mixture fully vibrate dissolving, ultrasonic 20-30s makes solution mix homogeneously;
3), use Rotary Evaporators to remove 2) in the organic solvent of mixed liquor, rotate at 40 DEG C and be evaporated up on wall to form faint yellow or transparent liposome membrane; At 62 DEG C, logical pure nitrogen gas continues dry 12h removing residual organic solvent;
4) the 0.3moL/L folic acid solution hydration 3 that, enchashment is joined) in dried liposome, the mixed proportion of folic acid solution and liposome is 300 μ L:1.9mg, the pH value of mixed liquor is 6.8, after the folic acid solution adding liposome is vibrated, it is positioned in the incubator of 50-55 DEG C 25-30min, makes it fully dissolve mixed liquor vibration every 5min; Then by the mixed liquor Ultrasonic Pulverization 3-5min of folic acid hydrated lipidic body; Mixed liquor after ultrasonic is loaded in 1mL syringe, releases 3-5 time from the polycarbonate membrane of 100nm, it is thus achieved that folic acid liposome, be saved in 4 DEG C of refrigerators;
Second step, mixed oil preparation:
1), 50%, 15% and 35% take Semen Maydis oil, Oleum Helianthi and walnut oil respectively and be sufficiently mixed by weight percentage, at 20 DEG C, stir 30min;
2), in 1) in the ratio of percentage by weight 0.03% of mixed oil take the folic acid liposome prepared in the first step and add in mixed oil after stirring 5min, by ultrasonic for mixed oil 15min, it is stirred 1min at interval of 5min, enables folic acid liposome to be uniformly distributed in mixed oil;
3), by 1) in the percentage by weight 0.019%, 0.021% of mixed oil respectively to 2) in the mixed oil for preparing adds butylhydroquinone and composite synergist continuously stirred 30min again, the mixed oil of mix homogeneously is loaded in aseptic tank, preserve under 20 DEG C of shady and cool conditions.
Hyperacoustic power of the ultrasonic use in above-mentioned steps is 380W, ultrasonic 3-5min when supersonic frequency is ultrasonic 30s interval 10s.
Claims (4)
1. the Semen Maydis oil mixed oil containing folic acid liposome, it is characterized in that: include Semen Maydis oil, Oleum Helianthi, walnut oil, folic acid liposome, butylhydroquinone and composite synergist, wherein Semen Maydis oil, percentage by weight shared by Oleum Helianthi and walnut oil is 45-55%, 15-23% and 28-35%, the addition of folic acid liposome is Semen Maydis oil, the 0.02-0.04% of Oleum Helianthi and walnut oil weight sum, the addition of butylhydroquinone is Semen Maydis oil, the 0.019% of Oleum Helianthi and walnut oil weight sum, the addition of composite synergist is Semen Maydis oil, the 0.021% of Oleum Helianthi and walnut oil weight sum.
2. a kind of Semen Maydis oil mixed oil containing folic acid liposome according to claim 1, it is characterised in that: described composite synergist is made up of citric acid and vitamin C, is 3:2 by weight citric acid and ascorbic mixed proportion.
3. the preparation method of the Semen Maydis oil mixed oil containing folic acid liposome, it is characterised in that: its concrete grammar is as described below:
The first step, folic acid liposome preparation:
1), measure hydrogenated soya phosphatide by weight 2.15-2.65:1 to mix with cholesterol, being subsequently adding trainingization PHOSPHATIDYL ETHANOLAMINE to carry out being sufficiently mixed uniformly, the weight ratio of trainingization PHOSPHATIDYL ETHANOLAMINE and hydrogenated soya phosphatide and cholesterol sum is 1:3.20-3.85;
2), take chloroform by 1) in mixture fully vibrate dissolving, ultrasonic 20-30s makes solution mix homogeneously;
3), use Rotary Evaporators to remove 2) in the organic solvent of mixed liquor, rotate at 40 DEG C and be evaporated up on wall to form faint yellow or transparent liposome membrane; At 62 DEG C, logical pure nitrogen gas continues dry 12h removing residual organic solvent;
4) the 0.3moL/L folic acid solution hydration 3 that, enchashment is joined) in dried liposome, the mixed proportion of folic acid solution and liposome is 300 μ L:1.758-2.139mg, the pH value of mixed liquor is 6.45-7, after the folic acid solution adding liposome is vibrated, it is positioned in the incubator of 50-55 DEG C 25-30min, makes it fully dissolve mixed liquor vibration every 5min; Then by the mixed liquor Ultrasonic Pulverization 3-5min of folic acid hydrated lipidic body; Mixed liquor after ultrasonic is loaded in 1mL syringe, releases 3-5 time from the polycarbonate membrane of 100nm, it is thus achieved that folic acid liposome, be saved in 4 DEG C of refrigerators;
Second step, mixed oil preparation:
1), by weight percentage 45-55%, 15-23% and 28-35% take Semen Maydis oil, Oleum Helianthi and walnut oil respectively and be sufficiently mixed, at 20 DEG C, stir 30min;
2), in 1) in the ratio of percentage by weight 0.02-0.04% of mixed oil take the folic acid liposome prepared in the first step and add in mixed oil after stirring 5min, by ultrasonic for mixed oil 15min, it is stirred 1min at interval of 5min, enables folic acid liposome to be uniformly distributed in mixed oil;
3), by 1) in the percentage by weight 0.019%, 0.021% of mixed oil respectively to 2) in the mixed oil for preparing adds butylhydroquinone and composite synergist continuously stirred 30min again, the mixed oil of mix homogeneously is loaded in aseptic tank, preserve under 20 DEG C of shady and cool conditions.
4. the preparation method of a kind of Semen Maydis oil mixed oil containing folic acid liposome according to claim 3, it is characterised in that: hyperacoustic power of described ultrasonic use is 380W, ultrasonic 3-5min when supersonic frequency is ultrasonic 30s interval 10s.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107156734A (en) * | 2017-05-19 | 2017-09-15 | 舒城圣桂食品有限公司 | A kind of eight treasures (choice ingredients of certain special dishes) wild vegetable |
| CN107969706A (en) * | 2017-12-20 | 2018-05-01 | 吉林大学 | A kind of nanoscale enteral nutrition preparation and preparation method thereof |
| CN112335745A (en) * | 2020-09-21 | 2021-02-09 | 武汉轻工大学 | Camellia seed oil blend oil rich in folic acid and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101755926A (en) * | 2009-07-27 | 2010-06-30 | 中粮北海粮油工业（天津）有限公司 | Nutritious and healthy unit edible vegetable oil |
| CN104351361A (en) * | 2014-11-24 | 2015-02-18 | 吉林大学 | Blending process and formula of high-folic-acid edible oil for pregnant women |
| CN104739766A (en) * | 2013-12-26 | 2015-07-01 | 华东理工大学 | Nanometer folic acid liposome and supercritical carbon dioxide preparation method thereof |
-
2016
- 2016-01-18 CN CN201610030399.7A patent/CN105660887A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101755926A (en) * | 2009-07-27 | 2010-06-30 | 中粮北海粮油工业（天津）有限公司 | Nutritious and healthy unit edible vegetable oil |
| CN104739766A (en) * | 2013-12-26 | 2015-07-01 | 华东理工大学 | Nanometer folic acid liposome and supercritical carbon dioxide preparation method thereof |
| CN104351361A (en) * | 2014-11-24 | 2015-02-18 | 吉林大学 | Blending process and formula of high-folic-acid edible oil for pregnant women |
Non-Patent Citations (1)
| Title |
|---|
| 童桂鸿等: "叶酸脂质体制备工艺优化及其稳定性研究", 《食品科学》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107156734A (en) * | 2017-05-19 | 2017-09-15 | 舒城圣桂食品有限公司 | A kind of eight treasures (choice ingredients of certain special dishes) wild vegetable |
| CN107969706A (en) * | 2017-12-20 | 2018-05-01 | 吉林大学 | A kind of nanoscale enteral nutrition preparation and preparation method thereof |
| CN107969706B (en) * | 2017-12-20 | 2021-07-13 | 吉林大学 | Nano-scale enteral nutrition preparation and preparation method thereof |
| CN112335745A (en) * | 2020-09-21 | 2021-02-09 | 武汉轻工大学 | Camellia seed oil blend oil rich in folic acid and preparation method thereof |
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| C06 | Publication | ||
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Application publication date: 20160615 |