CN105641508A - Throat-clearing tea beverage and preparation method thereof - Google Patents

Throat-clearing tea beverage and preparation method thereof Download PDF

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CN105641508A
CN105641508A CN201610021896.0A CN201610021896A CN105641508A CN 105641508 A CN105641508 A CN 105641508A CN 201610021896 A CN201610021896 A CN 201610021896A CN 105641508 A CN105641508 A CN 105641508A
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parts
herba
folium
radix
throat
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苏鸣
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Ningbo Baokoufu Food Co Ltd
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Ningbo Baokoufu Food Co Ltd
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    • A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00—Tea; Tea substitutes; Preparations thereof
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Abstract

The invention relates to a throat-clearing tea beverage and a preparation method thereof. The throat-clearing tea beverage is prepared from the medicinal raw materials of willowleaf hygrophila herb, bengal dayflower herb, white chinaure herb, Indian pentanema herb, Indian maesa herb, thinleaf crazyweed root, omei mountain bamboo shaving, ramie peel, unpleasant swallowwort herb, diversifolious buckthorn root or leaf, morus australis leaf, bitter bamboo leaf, Pacific raspberry herb, Himalayan prinsepia leaf, sowthistle-leaf ixeris seedling, fernleaf dichocarpum root, sharpfruit calanthodes herb, cairo morningglory root or leaf, common nandina leaf, strobilanthes cusia, chequer-shaped indocalamus leaf, rhizoma panasis japonici, common ammannia herb, ludisia discolor and maltitol. The throat-clearing tea beverage disclosed by the invention has the efficacies of clearing away heat and toxic material, removing heat from the blood, relieving exterior syndrome, promoting the subsidence of swelling, alleviating pain, nourishing yin and moisturizing the lung.

Description

A kind of throat-clearing tea beverage and preparation method thereof
Technical field
The present invention relates to a kind of throat-clearing tea beverage and preparation method thereof, belong to field of health-care beverage.
Background technology
Chronic pharyngitis is one of department of otorhinolaryngology commonly encountered diseases, frequently-occurring disease, multiple is born in adult, accounts for the 1%��4% of otolaryngologic disease, because the course of disease is long, and the easy recurrent exerbation of symptom, the impression not easily cured often is left to people. Pathological manifestations is pharyngeal mucosa chronic congestion, connective tissue and lymphadenosis under mucosa. The reason causing chronic pharyngitis is a lot, as: acute pharyngitis recurrent exerbation; Upper respiratory tract infection chronic stimulation; Tobacco and wine are excessive, harmful
Gas and eating irritable food; Occupational factor and systemic factor etc. The medicines such as western medical treatment chronic pharyngitis many employings vitamin, use Operand (on a small quantity), use the external treatment such as radio frequency, laser if desired, uncertain therapeutic efficacy is cut, although and by inustion, foreign body in pharynx sense is made moderate progress, but because destroying the reasons such as glandular secretion and the cicatricial contraction of mucosa, often make pharyngalgia, dry pharynx increase the weight of. Chinese medicine chronic pharyngitis has its unique curative effect than doctor trained in Western medicine.
The exploitation of throat-clearing tea beverage meets the trend of domestic beverage development, keeping on traditional basis, it is the guidance with Basic Theories of Chinese Medicine that throat-clearing tea beverage is cured the disease, carry out prescription compatibility, the modern times are utilized to extract the prepared beverage of processing technique, some are also shown up prominently with the functional food puted prevention first, and have wide market. Chronic pharyngitis can be played treatment and prevention purpose by the throat-clearing tea beverage that the present invention prepares, and has the advantage that side effect is little.
Summary of the invention
The present invention provides a kind of throat-clearing tea beverage and preparation method thereof, this throat-clearing tea beverage has heat-clearing and toxic substances removing, removing heat from blood induces sweat, effect of reducing swelling and alleviating pain, nourishing YIN and moistening the lung, chronic pharyngitis disease is had good treatment and prevention effect, and clinical efficacy is notable, have no adverse reaction and advantage that relapse rate is low.
Chronic pharyngitis is adenoid diffusivity inflammation under pharyngeal mucosa, mucosa. Chinese medicine thinks that chronic pharyngitis is many because of lung-dryness syndrome due to deficiency of YIN, raw in deficiency-heat, and pathogen is controlled for a long time and caused that QI-blood circulation is not smooth, and it is unfavorable to lift, and mental disorder pent-up is fallen ill in throat. In side, Herba Hygrophilae Salicifoliae, horse Auricled Hedyotis Herb, Herba Boenninghauseniae Albiflorae, Herba Pentanematis Indici, Herba Maesae Indicae, all medicines of Radix oxytropis leptophyllae match, can heat-clearing and toxic substances removing, dissipate pent up, sore-throat relieving, be equipped with again Caulis bambusae omeiensis, bark of Boehmeria mvea (L.)Gaud, Radix Tylophorae arenicolae, Radix Rhamni Heterophyllae, chicken Folium Mori, Folium Pleioblasti, Herba Ixeritis Sonchifoliae, Herba Calathodis Oxycarpae, temperature Folium Isatidis can clearing away heat and cooling blood, induce sweat lung qi dispersing; The merit of clearing away lung-heat can be strengthened;Add the effect in Herba Rubi Paicfici, Folium Prinsepiae Utilis, Radix Dichocarpi Dalzielii, Herba Ipomoeae Cairicae, Folium Nandinae domesticae, Folium indocalami tessellati, the Rhizoma Tupistrae ensifoliae side made from reducing swelling and alleviating pain; Last compatibility strangles pipe grass, blood aspidistra can YIN nourishing and the production of body fluid promoting. All side's medicines share, giving consideration to both the incidental and fundamental, play heat-clearing and toxic substances removing altogether, removing heat from blood induces sweat, the merit of reducing swelling and alleviating pain, nourishing YIN and moistening the lung.
The crude drug source of throat-clearing tea beverage of the present invention and effect are as follows:
Herba Hygrophilae Salicifoliae, for root or the herb of the short leaf cyperus malaccensis CyperusmalaccensisLam.var.brevifoliusBocklr of dried tuber kind of plant. Nature and flavor, lightly seasoned, cold in nature. Effect: clearing away heat and cooling blood, diuresis.
Horse Auricled Hedyotis Herb, for the herb of Commelianaceae plant CommelinahengalensisL rice packet grass. Nature and flavor, bitter, cold. Effect: heat-clearing and toxic substances removing, inducing diuresis to remove edema.
Herba Boenninghauseniae Albiflorae, for the herb of Folium Symplocoris Caudatae kind of plant Boenninghausenia albiflora. Nature and flavor, pungent light, cold. Effect: clearing away heat and cooling blood, relaxing muscles and tendons to promote blood circulation, antiinflammatory.
Herba Pentanematis Indici, carries on the back the herb of reed millet straw in vain for feverfew Pentanemaindicum. Nature and flavor, lightly seasoned, cool in nature. Effect: heat-clearing and toxic substances removing; Relieving stranguria by diuresis.
Herba Maesae Indicae, for Myrsinacea Herba Maesae Indicae Maesaindica (Roxb.) A.DC., is used as medicine with Herb. Nature and flavor, micro-hardship, cool. Effect: heat-clearing and toxic substances removing.
Radix oxytropis leptophyllae, for leguminous plant Oxytroisleptophylla(Pall.) root of DC. O.leptophylla. Nature and flavor, bitter, property, cool. Effect: heat-clearing and toxic substances removing.
Caulis bambusae omeiensis, for the intermediate layer scraped after the stem stalk removing crust of grass Neosinocalamusaffinis (Rendli) Kengf. cizu. Nature and flavor, sweet in the mouth, cold nature is nontoxic. Effect: clearing away heat and cooling blood, relieves restlessness and prevents vomiting.
Bark of Boehmeria mvea (L.)Gaud, for the peel of stem of contrayerva Boehmerianivea Boehmeria. Nature and flavor, cold in nature. Effect: clearing away heat and cooling blood, dissipating blood stasis stops blooding, diuresis of detoxifying, antiabortive galactopoiesis.
Radix Tylophorae arenicolae, the root and rhizome of peento in avenging for trailing plants section plant Cynanchuminamoenum (Maxim.) Loes.. Nature and flavor, pungent, flat. Effect: the kidney invigorating, spleen invigorating, removing toxic substances.
Radix Rhamni Heterophyllae, for root or the branch and leaf of Rhamnaceae plant precipice jujube tree Rhamnusheterophyllaoliv. Nature and flavor, cool in nature, the micro-hardship of puckery, nontoxic. Effect: heat clearing away, removing heat from blood, hemostasis.
Chicken Folium Mori, for the leaf of moraceae plants MorusaustralisPoir. chicken Mulberry. Nature and flavor, sweet, pungent, cold in nature. Effect: clearing away heat and expelling pathogen in the exterior, lung qi dispersing cough-relieving.
Folium Pleioblasti, for the tender leaf of grass bitter bamboo Pleioblastusamarus (Keng) Kengf. Nature and flavor, sweet, light, cold. Effect: clearing heat and relieving fidgetness, quenches one's thirst, diuresis.
Herba Rubi Paicfici, for the herb of dicotyledon Yao Wei section plant Herba Rubi Paicfici RubuspacificusHance. Nature and flavor, acrid in the mouth, hardship, acid, property is put down. Effect: heat clearing away, invigorates blood circulation.
Folium Prinsepiae Utilis, for Rosaceae Prinsepia Royle plant Folium Prinsepiae Utilis PrinsepiautilisRoyle, is used as medicine with root, leaf. Nature and flavor, bitter, pungent, cool. Effect: root, leaf: heat-clearing and toxic substances removing, promoting blood circulation and detumescence.
Herba Ixeritis Sonchifoliae, for Compositae open country gutweed platymiscium Herba Ixeritis Sonchifoliae Ixerissonchifolia(Bunge) Hance, with all herbal medicine. Nature and flavor, bitter, pungent, flat. Effect: heat-clearing and toxic substances removing, removing heat from blood, invigorate blood circulation, evacuation of pus.
Radix Dichocarpi Dalzielii, for the root of ranunculaceae plant Dichocarpumdalzielii (Drumm.etHutch.) fern leaf herringbone fruit. Nature and flavor, cold in nature, the micro-hardship of acrid in the mouth. Effect: detumescence, dissipates poison.
Herba Calathodis Oxycarpae, for Ranunculaceae Trollius Yunnan globeflower Trolliusyunnanensis(Franch.) herb of Ulbr..Nature and flavor, sweet, acrid, warm. Effect: induce sweat, cold expelling, disappear knot.
Herba Ipomoeae Cairicae, for root or the branch of moraceae plants FicushirtaVah ficus simplicissima. Nature and flavor, sweet; Micro-hardship; Property is put down. Effect: expelling wind and removing dampness, removing blood stasis to reduce swelling.
Folium Nandinae domesticae, for the leaf of Berberidaceae plant Fructus Nandinae Domesticae NandinadomesticaThunb.. Nature and flavor, bitter, cold in nature. Effect: clearing away heat-damp and promoting diuresis, pathogenic fire purging, removing toxic substances.
Temperature Folium Isatidis, for aerial parts or the root of acanthaceous plant Goldfussiapentstemonoides circle bud gold foot grass. Nature and flavor, bitter in the mouth; Pungent; Cold nature. Effect: heat-clearing and toxic substances removing; Blood cooling and ecchymoses removing.
Folium indocalami tessellati, for the leaf of grass FoliumIndocalamiTessellati Indocalanmus tessellatus. Nature and flavor, sweet, cold. Effect: clearing away heat to stop bleeding; Removing toxic substances and promoting subsidence of swelling.
Rhizoma Tupistrae ensifoliae, for the rhizome of Araliaceae Reinecheacarnea Rhizoma Panacis Japonici. Nature and flavor, sweet in the mouth, micro-hardship, slightly warm in nature. Effect: Xu-tonic; Eliminating phlegm and stopping cough; Dissipating blood stasis stops blooding; Reducing swelling and alleviating pain.
Le pipe grass, for the herb of contrayerva Lecanthuspeduncularis (Wall.exRoyle) Wedd. Herba Lecanthi peduncularis. Nature and flavor, sweet, property, cold. Effect: nourishing the lung to arrest cough.
Blood aspidistra, for orchid: Ludisiadiscolor(Ker-Gawl.) herb of A.Rich blood aspidistra. Nature and flavor, sweet in the mouth; Cool in nature. Effect: nourishing YIN and moistening the lung; Spleen invigorating; Calm the nerves.
The consumption of the throat-clearing tea beverage of the present invention also is groped to sum up from substantial amounts of clinical practice and is drawn, and each amounts of components all has good curative effect in following weight parts scope:
Throat-clearing tea beverage of the present invention is prepared by the crude drug composition of weight portion: Herba Hygrophilae Salicifoliae 50��70 parts, horse Auricled Hedyotis Herb 50��70 parts, Herba Boenninghauseniae Albiflorae 30��50 parts, Herba Pentanematis Indici 30��50 parts, Herba Maesae Indicae 20��40 parts, Radix oxytropis leptophyllae 20��40 parts, Caulis bambusae omeiensis 10��30 parts, bark of Boehmeria mvea (L.)Gaud 10��30 parts, Radix Tylophorae arenicolae 20��40 parts, Radix Rhamni Heterophyllae 30��50 parts, 10��30 parts of chicken Folium Mori, Folium Pleioblasti 20��40 parts, Herba Rubi Paicfici 10��30 parts, Folium Prinsepiae Utilis 30��50 parts, Herba Ixeritis Sonchifoliae 5��15 parts, Radix Dichocarpi Dalzielii 10��30 parts, Herba Calathodis Oxycarpae 10��30 parts, Herba Ipomoeae Cairicae 5��15 parts, Folium Nandinae domesticae 10��30 parts, temperature Folium Isatidis 20��40 parts, Folium indocalami tessellati 10��30 parts, Rhizoma Tupistrae ensifoliae 30��50 parts, strangle pipe grass 20��40 parts, blood aspidistra 5��15 parts, maltose alcohol 5��15 parts.
Preferably, throat-clearing tea beverage of the present invention is made up of the crude drug of following weight portion: Herba Hygrophilae Salicifoliae 60 parts, horse Auricled Hedyotis Herb 60 parts, Herba Boenninghauseniae Albiflorae 40 parts, Herba Pentanematis Indici 40 parts, Herba Maesae Indicae 30 parts, Radix oxytropis leptophyllae 30 parts, Caulis bambusae omeiensis 20 parts, bark of Boehmeria mvea (L.)Gaud 20 parts, Radix Tylophorae arenicolae 30 parts, Radix Rhamni Heterophyllae 40 parts, 20 parts of chicken Folium Mori, Folium Pleioblasti 30 parts, Herba Rubi Paicfici 20 parts, Folium Prinsepiae Utilis 40 parts, Herba Ixeritis Sonchifoliae 10 parts, Radix Dichocarpi Dalzielii 20 parts, Herba Calathodis Oxycarpae 20 parts, Herba Ipomoeae Cairicae 10 parts, Folium Nandinae domesticae 20 parts, temperature Folium Isatidis 30 parts, Folium indocalami tessellati 20 parts, Rhizoma Tupistrae ensifoliae 40 parts, strangle pipe grass 30 parts, blood aspidistra 10 parts, maltose alcohol 10 parts.
Preferably, throat-clearing tea beverage of the present invention is made up of the crude drug of following weight portion: Herba Hygrophilae Salicifoliae 50 parts, horse Auricled Hedyotis Herb 70 parts, Herba Boenninghauseniae Albiflorae 30 parts, Herba Pentanematis Indici 50 parts, Herba Maesae Indicae 40 parts, Radix oxytropis leptophyllae 20 parts, Caulis bambusae omeiensis 10 parts, bark of Boehmeria mvea (L.)Gaud 30 parts, Radix Tylophorae arenicolae 40 parts, Radix Rhamni Heterophyllae 50 parts, 30 parts of chicken Folium Mori, Folium Pleioblasti 40 parts, Herba Rubi Paicfici 10 parts, Folium Prinsepiae Utilis 50 parts, Herba Ixeritis Sonchifoliae 15 parts, Radix Dichocarpi Dalzielii 30 parts, Herba Calathodis Oxycarpae 10 parts, Herba Ipomoeae Cairicae 5 parts, Folium Nandinae domesticae 10 parts, temperature Folium Isatidis 40 parts, Folium indocalami tessellati 10 parts, Rhizoma Tupistrae ensifoliae 50 parts, strangle pipe grass 20 parts, blood aspidistra 15 parts, maltose alcohol 5 parts.
Preferably, throat-clearing tea beverage of the present invention is made up of the crude drug of following weight portion: Herba Hygrophilae Salicifoliae 70 parts, horse Auricled Hedyotis Herb 50 parts, Herba Boenninghauseniae Albiflorae 50 parts, Herba Pentanematis Indici 30 parts, Herba Maesae Indicae 20 parts, Radix oxytropis leptophyllae 40 parts, Caulis bambusae omeiensis 30 parts, bark of Boehmeria mvea (L.)Gaud 10 parts, Radix Tylophorae arenicolae 20 parts, Radix Rhamni Heterophyllae 30 parts, 10 parts of chicken Folium Mori, Folium Pleioblasti 20 parts, Herba Rubi Paicfici 30 parts, Folium Prinsepiae Utilis 30 parts, Herba Ixeritis Sonchifoliae 5 parts, Radix Dichocarpi Dalzielii 10 parts, Herba Calathodis Oxycarpae 30 parts, Herba Ipomoeae Cairicae 15 parts, Folium Nandinae domesticae 30 parts, temperature Folium Isatidis 20 parts, Folium indocalami tessellati 30 parts, Rhizoma Tupistrae ensifoliae 30 parts, strangle pipe grass 40 parts, blood aspidistra 5 parts, maltose alcohol 15 parts.
The preparation method of throat-clearing tea beverage of the present invention, is prepared by step composition:
(1) take the Herba Hygrophilae Salicifoliae of prescribed dose proportioning, horse Auricled Hedyotis Herb, Herba Boenninghauseniae Albiflorae, Herba Pentanematis Indici, Herba Maesae Indicae, Radix oxytropis leptophyllae, Caulis bambusae omeiensis, bark of Boehmeria mvea (L.)Gaud, Radix Tylophorae arenicolae, Radix Rhamni Heterophyllae, chicken Folium Mori, Folium Pleioblasti, Herba Rubi Paicfici, Folium Prinsepiae Utilis, Herba Ixeritis Sonchifoliae, Radix Dichocarpi Dalzielii, Herba Calathodis Oxycarpae, Herba Ipomoeae Cairicae, Folium Nandinae domesticae, temperature Folium Isatidis, Folium indocalami tessellati, Rhizoma Tupistrae ensifoliae, Le pipe grass, blood aspidistra medical material, add the soak by water 1��3 time that medical material weight ratio is 8��12 times amount, each 0.5��2h, filter, merge to obtain middle drug filtrate
(2) adding the chitosan of step (1) Chinese medicine filtrate quality mark 0.04��0.06%, stir evenly 10��20min 60��70 DEG C of heating, cold preservation stands 12��24h, prepares purification of tcm liquid;
Take step againPurification of tcm liquid, addition maltose alcohol, stir, and homogenizing under 20��40MPa pressure obtains homogenizing medicinal liquid;
Again by step homogenizing medicinal liquid (3), carry out sterilization in open kettle, in temperature 85��95 DEG C, time 30��50min, cooling.
Preferably, the preparation method of throat-clearing tea beverage of the present invention, it is prepared by step composition:
(1) take the Herba Hygrophilae Salicifoliae of prescribed dose proportioning, horse Auricled Hedyotis Herb, Herba Boenninghauseniae Albiflorae, Herba Pentanematis Indici, Herba Maesae Indicae, Radix oxytropis leptophyllae, Caulis bambusae omeiensis, bark of Boehmeria mvea (L.)Gaud, Radix Tylophorae arenicolae, Radix Rhamni Heterophyllae, chicken Folium Mori, Folium Pleioblasti, Herba Rubi Paicfici, Folium Prinsepiae Utilis, Herba Ixeritis Sonchifoliae, Radix Dichocarpi Dalzielii, Herba Calathodis Oxycarpae, Herba Ipomoeae Cairicae, Folium Nandinae domesticae, temperature Folium Isatidis, Folium indocalami tessellati, Rhizoma Tupistrae ensifoliae, Le pipe grass, blood aspidistra medical material, add the soak by water 2 times that medical material weight ratio is 10 times amount, each 1h, filter, merge to obtain middle drug filtrate
(2) the 65 DEG C of heating of chitosan adding step (1) Chinese medicine filtrate quality mark 0.05% stir evenly 15min, and cold preservation stands 18h, prepare purification of tcm liquid;
Take step againPurification of tcm liquid, addition maltose alcohol, stir, and homogenizing under 30MPa pressure obtains homogenizing medicinal liquid;
Again by step homogenizing medicinal liquid (3), carry out sterilization in open kettle, in temperature 90 DEG C, time 40min, cooling.
The method of inspection of throat-clearing tea drinks principal ingredient of the present invention
Total polysaccharides: adopt Anthrone-sulfuricacid method, be measured; Total flavones: adopt with sodium nitrite-aluminum nitrate-sodium-hydroxide method ultraviolet determination; Colorimetry; Protein: Kjeldahl's method; Ash: burning weight method.
Table 1 throat-clearing tea drinks principal ingredient measurement result of the present invention
The beneficial effect of throat-clearing tea beverage of the present invention:
The prescription of throat-clearing tea beverage of the present invention is under theory of Chinese medical science and clinical experience instruct, choose each crude drug and prescribed dose proportioning thereof, utilize the compatibility theory of Chinese medicine monarch so that the generation synergism that each medicine is mutual, improve the clinical efficacy of full side. Throat-clearing tea beverage of the present invention contains plurality of active ingredients and includes total polysaccharides, total flavones, protein etc. so that have resistance against diseases antibacterial, antiviral, antiinflammatory, relief of symptoms, enhancing body, promotes the effect of the reparation of tissue injury.Clinical trial have received good therapeutic effect. Side adds maltose alcohol, it is possible to regulate the taste of throat-clearing tea of the present invention so that delicate fragrance is pure.
According to clinical verification, the overall clinical efficacy rate of throat-clearing tea beverage of the present invention is 94.7%, effective in cure notable, the treated effect height of this throat-clearing tea beverage vessel, the advantage that side effect is little. For diseases such as chronic pharyngitis, pharyngeal dryness, hoarseness.
Detailed description of the invention
The following is the specific embodiment of present invention, for setting forth the technical scheme solving technical problem in present specification, contribute to skilled artisan understands that present invention, but the realization of technical solution of the present invention is not limited to these embodiments.
Embodiment 1
(1) take Herba Hygrophilae Salicifoliae 60g, horse Auricled Hedyotis Herb 60g, Herba Boenninghauseniae Albiflorae 40g, Herba Pentanematis Indici 40g, Herba Maesae Indicae 30g, Radix oxytropis leptophyllae 30g, Caulis bambusae omeiensis 20g, bark of Boehmeria mvea (L.)Gaud 20g, Radix Tylophorae arenicolae 30g, Radix Rhamni Heterophyllae 40g, chicken Folium Mori 20g, Folium Pleioblasti 30g, Herba Rubi Paicfici 20g, Folium Prinsepiae Utilis 40g, Herba Ixeritis Sonchifoliae 10g, Radix Dichocarpi Dalzielii 20g, Herba Calathodis Oxycarpae 20g, Herba Ipomoeae Cairicae 10g, Folium Nandinae domesticae 20g, temperature Folium Isatidis 30g, Folium indocalami tessellati 20g, Rhizoma Tupistrae ensifoliae 40g, strangle pipe grass 30g, blood aspidistra 10g, add the soak by water 2 times that medical material weight ratio is 10 times amount, each 1h, filter, merge to obtain middle drug filtrate;
(2) adding the chitosan of step (1) Chinese medicine filtrate quality mark 0.05%, stir evenly 15min 65 DEG C of heating, cold preservation stands 18h, prepares purification of tcm liquid;
Take step againPurification of tcm liquid, addition maltose alcohol, stir, and homogenizing under 30MPa pressure obtains homogenizing medicinal liquid;
Again by step homogenizing medicinal liquid (3), carry out sterilization in open kettle, in temperature 90 DEG C, time 40min, cooling.
Embodiment 2
(1) take Herba Hygrophilae Salicifoliae 50g, horse Auricled Hedyotis Herb 70g, Herba Boenninghauseniae Albiflorae 30g, Herba Pentanematis Indici 50g, Herba Maesae Indicae 40g, Radix oxytropis leptophyllae 20g, Caulis bambusae omeiensis 10g, bark of Boehmeria mvea (L.)Gaud 30g, Radix Tylophorae arenicolae 40g, Radix Rhamni Heterophyllae 50g, chicken Folium Mori 30g, Folium Pleioblasti 40g, Herba Rubi Paicfici 10g, Folium Prinsepiae Utilis 50g, Herba Ixeritis Sonchifoliae 15g, Radix Dichocarpi Dalzielii 30g, Herba Calathodis Oxycarpae 10g, Herba Ipomoeae Cairicae 5g, Folium Nandinae domesticae 10g, temperature Folium Isatidis 40g, Folium indocalami tessellati 10g, Rhizoma Tupistrae ensifoliae 50g, strangle pipe grass 20g, blood aspidistra 15g, add the soak by water 1 time that medical material weight ratio is 12 times amount, each 2h, filter, merge to obtain middle drug filtrate;
(2) adding the chitosan of step (1) Chinese medicine filtrate quality mark 0.04%, stir evenly 10min 70 DEG C of heating, cold preservation stands 12h, prepares purification of tcm liquid;
Take step againPurification of tcm liquid, addition maltose alcohol, stir, and homogenizing under 20MPa pressure obtains homogenizing medicinal liquid;
Again by step homogenizing medicinal liquid (3), carry out sterilization in open kettle, in temperature 95 DEG C, time 30min, cooling.
Embodiment 3
(1) take Herba Hygrophilae Salicifoliae 70g, horse Auricled Hedyotis Herb 50g, Herba Boenninghauseniae Albiflorae 50g, Herba Pentanematis Indici 30g, Herba Maesae Indicae 20g, Radix oxytropis leptophyllae 40g, Caulis bambusae omeiensis 30g, bark of Boehmeria mvea (L.)Gaud 10g, Radix Tylophorae arenicolae 20g, Radix Rhamni Heterophyllae 30g, chicken Folium Mori 10g, Folium Pleioblasti 20g, Herba Rubi Paicfici 30g, Folium Prinsepiae Utilis 30g, Herba Ixeritis Sonchifoliae 5g, Radix Dichocarpi Dalzielii 10g, Herba Calathodis Oxycarpae 30g, Herba Ipomoeae Cairicae 15g, Folium Nandinae domesticae 30g, temperature Folium Isatidis 20g, Folium indocalami tessellati 30g, Rhizoma Tupistrae ensifoliae 30g, strangle pipe grass 40g, blood aspidistra 5g, add the soak by water 3 times that medical material weight ratio is 8 times amount, each 0.5h, filter, merge to obtain middle drug filtrate;
(2) adding the chitosan of step (1) Chinese medicine filtrate quality mark 0.06%, stir evenly 20min 60 DEG C of heating, cold preservation stands 24h, prepares purification of tcm liquid;
Take step againPurification of tcm liquid, addition maltose alcohol, stir, and homogenizing under 40MPa pressure obtains homogenizing medicinal liquid;
Again by step homogenizing medicinal liquid (3), carry out sterilization in open kettle, in temperature 85 DEG C, time 50min, cooling.
In order to verify the curative effect of throat-clearing tea beverage of the present invention further, carry out corresponding clinical trial according to the throat-clearing tea beverage of preparation in embodiment 1, now result is reported as follows.
The clinical observation of throat-clearing tea beverage of the present invention and curative effect
1 clinical data
1.1 physical data
Choose in October, 2014��2015 year and accept 154 example patients with chronic pharyngitis for medical treatment August, be randomly divided into treatment group and matched group. Wherein treatment group 76 example, male 35 examples, female 41 example; 21��63 years old age, average 38.3 years old; The course of disease 3 months to 2.1 years, average 11.5 months. Matched group 68 example, male 31 examples, female 37 example; 23��64 years old age, average 40.4 years old; The course of disease 4 months to 2.6 years, average 12.3 months. Physical data, through statistical procedures, there was no significant difference (P > 0.05), has comparability.
1.2 diagnostic criterias
Have with reference to patients symptomatic's main manifestations in " traditional Chinese medical science hals,Nasen und Ohrenheilkunde disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine issues for 1994: bottleneck throat has foreign body sensation, gargalesthesia, burning sensation, dry sensation or hypodynia, the few expectorant of thirsty or dry cough, pharyngeal congestion, retropharyneal folliculosis are shown in bottleneck throat inspection. And get rid of the patient suffering from cardiovascular and cerebrovascular vessel, malignant tumor, obnubilation and disease of immune system.
1.3 Therapeutic Method
1.3.1 treatment group
The patient for the treatment of group gives the throat-clearing tea beverage of the embodiment of the present invention 1 group, and oral, 50ml/ time, every day 3 times, 7 days is a course for the treatment of, serve on 2 courses for the treatment of.
1.3.2 matched group
Matched group patient takes throat-benefiting granule (Gui Long pharmaceutcal corporation, Ltd), and boiled water is taken after mixing it with water. One time 1 bag, 3 times on the one, 7 days be a course for the treatment of. Avoid eating anything raw or cold during treatment, pungent scorching product, note oral hygiene.
Two groups of patients avoided eating anything raw or cold maror in period of taking medicine, and did not use other drug, treated 2 courses for the treatment of, and follow up a case by regular visits to 2 months, and itemized record patient is in the various untoward reaction of medication period and follow-up period.
1.4 observation of curative effect
1.4.1 criterion of therapeutical effect
To two groups of patient clinical therapeutic effect, the clinical symptoms of the symptoms such as laryngopharynx swelling and pain, foreign body in pharynx sense and cough expectorant are thick takes a turn for the better the time, and treatment and follow up a case by regular visits to middle untoward reaction a situation arises and compare analysis. With reference to " traditional Chinese medical science hals,Nasen und Ohrenheilkunde disease Standardization of diagnosis and curative effect ": 1. cure: the symptoms such as pharyngeal sense of discomfort and sticky secretions substantially disappear, lymph follicle and local pharyngeal congestion substantially disappear; 2. effective: the symptoms such as pharyngeal sense of discomfort and sticky secretions substantially alleviate, lymph foilicie hyperplasia, and locally pharyngeal congestion is clearly better; 3. effective: the symptoms such as pharyngeal sense of discomfort and sticky secretions are alleviated to some extent, lymph foilicie hyperplasia and local pharyngeal congestion alleviate to some extent; 4. invalid: all clinical symptoms are all unchanged, even worsen. Total effective rate is cure rate, obvious effective rate and effective percentage sum.
1.4.2 statistical analysis
Adopting statistic software SPSS 13.0 to process data, adopt inspection, P < 0.05 is statistically significant.
1.5 therapeutic outcomes
2.1 result of the tests are in Table 2.
2 liang of table group patient clinical symptom take a turn for the better the time comparison (my god)
Group n Laryngopharynx swelling and pain Foreign body in pharynx sense Cough expectorant is thick
Treatment group 76 3.09��1.01* 3.12��0.98* 4.06��1.34*
Matched group 68 4.68��1.25 4.56��1.16 5.43��1.56
Note: compared with matched group, * P < 0.05.
Result shows, compared with matched group, the improvement time of the clinical symptoms such as the laryngopharynx swelling and pain for the treatment of group patient, foreign body in pharynx sense and cough expectorant are thick substantially shortens, and has statistical significance (P < 0.05), and this also illustrates that throat-clearing tea beverage of the present invention has significant curative effect to improving patients symptomatic.
3 liang of table group patient clinical symptom take a turn for the better the time comparison (my god)
Group n Cure Effective Effectively Invalid Total effective rate
Treatment group 76 42 19 11 4 94.7%*
Matched group 68 27 16 10 15 77.9%
Note: compared with matched group, * P < 0.05.
It is shown that after the treatment of 2 courses for the treatment of, the symptom such as the pharyngeal sense of discomfort of the patient for the treatment of group and sticky secretions substantially disappears, and lymph follicle and local pharyngeal congestion substantially disappear. Comparing with matched group, cure rate and the total effective rate for the treatment of group patient significantly improve, and difference has statistical significance (P < 0.05).
2.2 recurrences
Through following up a case by regular visits to 6 months, in 42 examples for the treatment of group recovery from illness, 1 case relapsed, relapse rate 2.4%; Matched group (throat-benefiting granule) is cured in 27 examples, recurs 4 examples, relapse rate 14.8%. Treatment group compares significant difference (P < 0.05) with matched group Patients on Recurrence rate. Two groups of patients in treatment and follow up a case by regular visits in process, and all patients all occur without adverse effect.
In sum, chronic pharyngitis disease is had significant therapeutic effect and the low advantage of relapse rate by throat-clearing tea beverage of the present invention. This step illustrates, throat-clearing tea beverage of the present invention has good market application foreground.

Claims (7)

1. a throat-clearing tea beverage, it is characterized in that, mainly it is made up of the crude drug of following weight portion: Herba Hygrophilae Salicifoliae 50��70 parts, horse Auricled Hedyotis Herb 50��70 parts, Herba Boenninghauseniae Albiflorae 30��50 parts, Herba Pentanematis Indici 30��50 parts, Herba Maesae Indicae 20��40 parts, Radix oxytropis leptophyllae 20��40 parts, Caulis bambusae omeiensis 10��30 parts, bark of Boehmeria mvea (L.)Gaud 10��30 parts, Radix Tylophorae arenicolae 20��40 parts, Radix Rhamni Heterophyllae 30��50 parts, 10��30 parts of chicken Folium Mori, Folium Pleioblasti 20��40 parts, Herba Rubi Paicfici 10��30 parts, Folium Prinsepiae Utilis 30��50 parts, Herba Ixeritis Sonchifoliae 5��15 parts, Radix Dichocarpi Dalzielii 10��30 parts, Herba Calathodis Oxycarpae 10��30 parts, Herba Ipomoeae Cairicae 5��15 parts, Folium Nandinae domesticae 10��30 parts, temperature Folium Isatidis 20��40 parts, Folium indocalami tessellati 10��30 parts, Rhizoma Tupistrae ensifoliae 30��50 parts, strangle pipe grass 20��40 parts, blood aspidistra 5��15 parts, maltose alcohol 5��15 parts.
2. throat-clearing tea beverage as claimed in claim 1, it is characterized in that, mainly it is made up of the crude drug of following weight portion: Herba Hygrophilae Salicifoliae 60 parts, horse Auricled Hedyotis Herb 60 parts, Herba Boenninghauseniae Albiflorae 40 parts, Herba Pentanematis Indici 40 parts, Herba Maesae Indicae 30 parts, Radix oxytropis leptophyllae 30 parts, Caulis bambusae omeiensis 20 parts, bark of Boehmeria mvea (L.)Gaud 20 parts, Radix Tylophorae arenicolae 30 parts, Radix Rhamni Heterophyllae 40 parts, 20 parts of chicken Folium Mori, Folium Pleioblasti 30 parts, Herba Rubi Paicfici 20 parts, Folium Prinsepiae Utilis 40 parts, Herba Ixeritis Sonchifoliae 10 parts, Radix Dichocarpi Dalzielii 20 parts, Herba Calathodis Oxycarpae 20 parts, Herba Ipomoeae Cairicae 10 parts, Folium Nandinae domesticae 20 parts, temperature Folium Isatidis 30 parts, Folium indocalami tessellati 20 parts, Rhizoma Tupistrae ensifoliae 40 parts, strangle pipe grass 30 parts, blood aspidistra 10 parts, maltose alcohol 10 parts.
3. throat-clearing tea beverage as claimed in claim 1, it is characterized in that, mainly it is made up of the crude drug of following weight portion: Herba Hygrophilae Salicifoliae 50 parts, horse Auricled Hedyotis Herb 70 parts, Herba Boenninghauseniae Albiflorae 30 parts, Herba Pentanematis Indici 50 parts, Herba Maesae Indicae 40 parts, Radix oxytropis leptophyllae 20 parts, Caulis bambusae omeiensis 10 parts, bark of Boehmeria mvea (L.)Gaud 30 parts, Radix Tylophorae arenicolae 40 parts, Radix Rhamni Heterophyllae 50 parts, 30 parts of chicken Folium Mori, Folium Pleioblasti 40 parts, Herba Rubi Paicfici 10 parts, Folium Prinsepiae Utilis 50 parts, Herba Ixeritis Sonchifoliae 15 parts, Radix Dichocarpi Dalzielii 30 parts, Herba Calathodis Oxycarpae 10 parts, Herba Ipomoeae Cairicae 5 parts, Folium Nandinae domesticae 10 parts, temperature Folium Isatidis 40 parts, Folium indocalami tessellati 10 parts, Rhizoma Tupistrae ensifoliae 50 parts, strangle pipe grass 20 parts, blood aspidistra 15 parts, maltose alcohol 5 parts.
4. throat-clearing tea beverage as claimed in claim 1, it is characterized in that, mainly it is made up of the crude drug of following weight portion: Herba Hygrophilae Salicifoliae 70 parts, horse Auricled Hedyotis Herb 50 parts, Herba Boenninghauseniae Albiflorae 50 parts, Herba Pentanematis Indici 30 parts, Herba Maesae Indicae 20 parts, Radix oxytropis leptophyllae 40 parts, Caulis bambusae omeiensis 30 parts, bark of Boehmeria mvea (L.)Gaud 10 parts, Radix Tylophorae arenicolae 20 parts, Radix Rhamni Heterophyllae 30 parts, 10 parts of chicken Folium Mori, Folium Pleioblasti 20 parts, Herba Rubi Paicfici 30 parts, Folium Prinsepiae Utilis 30 parts, Herba Ixeritis Sonchifoliae 5 parts, Radix Dichocarpi Dalzielii 10 parts, Herba Calathodis Oxycarpae 30 parts, Herba Ipomoeae Cairicae 15 parts, Folium Nandinae domesticae 30 parts, temperature Folium Isatidis 20 parts, Folium indocalami tessellati 30 parts, Rhizoma Tupistrae ensifoliae 30 parts, strangle pipe grass 40 parts, blood aspidistra 5 parts, maltose alcohol 15 parts.
5. the preparation method of the throat-clearing tea beverage as described in arbitrary in claim 1-4, it is characterised in that described preparation method is prepared by step composition:
(1) take the Herba Hygrophilae Salicifoliae of prescribed dose proportioning, horse Auricled Hedyotis Herb, Herba Boenninghauseniae Albiflorae, Herba Pentanematis Indici, Herba Maesae Indicae, Radix oxytropis leptophyllae, Caulis bambusae omeiensis, bark of Boehmeria mvea (L.)Gaud, Radix Tylophorae arenicolae, Radix Rhamni Heterophyllae, chicken Folium Mori, Folium Pleioblasti, Herba Rubi Paicfici, Folium Prinsepiae Utilis, Herba Ixeritis Sonchifoliae, Radix Dichocarpi Dalzielii, Herba Calathodis Oxycarpae, Herba Ipomoeae Cairicae, Folium Nandinae domesticae, temperature Folium Isatidis, Folium indocalami tessellati, Rhizoma Tupistrae ensifoliae, Le pipe grass, blood aspidistra medical material, add the soak by water 1��3 time that medical material weight ratio is 8��12 times amount, each 0.5��2h, filter, merge to obtain middle drug filtrate;
(2) adding the chitosan of step (1) Chinese medicine filtrate quality mark 0.04��0.06%, stir evenly 10��20min 60��70 DEG C of heating, cold preservation stands 12��24h, prepares purification of tcm liquid;
Take step againPurification of tcm liquid, addition maltose alcohol, stir, and homogenizing under 20��40MPa pressure obtains homogenizing medicinal liquid;
Again by step homogenizing medicinal liquid (3), carry out sterilization in open kettle, in temperature 85��95 DEG C, time 30��50min, cooling.
6. the preparation method of throat-clearing tea beverage as claimed in claim 5, is prepared by step composition:
(1) take the Herba Hygrophilae Salicifoliae of prescribed dose proportioning, horse Auricled Hedyotis Herb, Herba Boenninghauseniae Albiflorae, Herba Pentanematis Indici, Herba Maesae Indicae, Radix oxytropis leptophyllae, Caulis bambusae omeiensis, bark of Boehmeria mvea (L.)Gaud, Radix Tylophorae arenicolae, Radix Rhamni Heterophyllae, chicken Folium Mori, Folium Pleioblasti, Herba Rubi Paicfici, Folium Prinsepiae Utilis, Herba Ixeritis Sonchifoliae, Radix Dichocarpi Dalzielii, Herba Calathodis Oxycarpae, Herba Ipomoeae Cairicae, Folium Nandinae domesticae, temperature Folium Isatidis, Folium indocalami tessellati, Rhizoma Tupistrae ensifoliae, Le pipe grass, blood aspidistra medical material, add the soak by water 2 times that medical material weight ratio is 10 times amount, each 1h, filter, merge to obtain middle drug filtrate;
(2) the 65 DEG C of heating of chitosan adding step (1) Chinese medicine filtrate quality mark 0.05% stir evenly 15min, and cold preservation stands 18h, prepare purification of tcm liquid;
Take step againPurification of tcm liquid, addition maltose alcohol, stir, and homogenizing under 30MPa pressure obtains homogenizing medicinal liquid;
Again by step homogenizing medicinal liquid (3), carry out sterilization in open kettle, in temperature 90 DEG C, time 40min, cooling.
7. the application in preparation treatment chronic pharyngitis medicine of the throat-clearing tea beverage as described in arbitrary in claim 1-4.
CN201610021896.0A 2016-01-14 2016-01-14 Throat-clearing tea beverage and preparation method thereof Pending CN105641508A (en)

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CN102960505A (en) * 2012-12-03 2013-03-13 罗生芳 Tea for clearing throat and preparation method thereof
CN103893565A (en) * 2013-12-27 2014-07-02 兴义市东泰天然果蔬开发有限公司 Throat-clearing and cough-relieving tea and making method thereof
CN105146003A (en) * 2015-10-12 2015-12-16 宁波好口味食品有限公司 Health tea drink and preparation method thereof

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CN101574470A (en) * 2008-05-09 2009-11-11 北京因科瑞斯医药科技有限公司 Composition with function of clearing throat and preparation method thereof
CN102726585A (en) * 2012-05-29 2012-10-17 桂龙药业(安徽)有限公司 Throat-clearing health food and preparation method thereof
CN102960505A (en) * 2012-12-03 2013-03-13 罗生芳 Tea for clearing throat and preparation method thereof
CN103893565A (en) * 2013-12-27 2014-07-02 兴义市东泰天然果蔬开发有限公司 Throat-clearing and cough-relieving tea and making method thereof
CN105146003A (en) * 2015-10-12 2015-12-16 宁波好口味食品有限公司 Health tea drink and preparation method thereof

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Application publication date: 20160608