CN105640533A - In-vitro hemodynamic characteristic test device - Google Patents
In-vitro hemodynamic characteristic test device Download PDFInfo
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- CN105640533A CN105640533A CN201510973644.3A CN201510973644A CN105640533A CN 105640533 A CN105640533 A CN 105640533A CN 201510973644 A CN201510973644 A CN 201510973644A CN 105640533 A CN105640533 A CN 105640533A
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- 238000012360 testing method Methods 0.000 title claims abstract description 129
- 230000000004 hemodynamic effect Effects 0.000 title abstract description 7
- 238000000338 in vitro Methods 0.000 title abstract 3
- 230000017531 blood circulation Effects 0.000 claims abstract description 46
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 41
- 239000000741 silica gel Substances 0.000 claims abstract description 41
- 229910002027 silica gel Inorganic materials 0.000 claims abstract description 41
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 28
- 239000002245 particle Substances 0.000 claims abstract description 24
- 239000008280 blood Substances 0.000 claims abstract description 23
- 210000004369 blood Anatomy 0.000 claims abstract description 23
- 210000004204 blood vessel Anatomy 0.000 claims description 19
- 239000000523 sample Substances 0.000 claims description 3
- 230000005540 biological transmission Effects 0.000 claims description 2
- 230000003628 erosive effect Effects 0.000 claims description 2
- 230000035945 sensitivity Effects 0.000 claims description 2
- 239000012890 simulated body fluid Substances 0.000 claims description 2
- 230000000007 visual effect Effects 0.000 claims description 2
- 238000004088 simulation Methods 0.000 abstract description 6
- 230000004087 circulation Effects 0.000 abstract 1
- 230000010349 pulsation Effects 0.000 abstract 1
- 239000000700 radioactive tracer Substances 0.000 abstract 1
- 238000010586 diagram Methods 0.000 description 6
- 238000004891 communication Methods 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 239000012530 fluid Substances 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 229920001296 polysiloxane Polymers 0.000 description 4
- 238000010008 shearing Methods 0.000 description 3
- 230000000747 cardiac effect Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000004304 visual acuity Effects 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000000541 pulsatile effect Effects 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000012858 resilient material Substances 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
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- Medical Informatics (AREA)
- Physics & Mathematics (AREA)
- Cardiology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physiology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Abstract
The invention relates to an in-vitro hemodynamic characteristic test device. The in-vitro hemodynamic characteristic test device mainly comprises a constant-temperature control box, a peristaltic pump, a pressure sensor, a non-contact microscope velocity-measuring system and the like. The constant-temperature control box is connected through a pipeline and forms a closed circulation loop, simulation blood containing tracer particles is placed in the constant-temperature control box, and an outlet of the constant-temperature control box penetrates through the peristaltic pump through a silica gel hose and is connected with an inlet of the constant-temperature control box through a testing region transparent elastic hose; valves are installed at the connecting positions of the silica gel hose and the testing region transparent elastic hose respectively on the front and rear portion of a testing region, and the testing region transparent elastic hose is connected with the silica gel hose through silica gel connectors; the pressure sensor and the non-contact microscope velocity-measuring system are installed at the test section position of the testing region transparent elastic hose. The test device can provide continuous simulation pulsation blood flow, is provided with a hemodynamic characteristic parameter testing system and is capable of testing hemodynamic characteristic parameters such as blood flow velocity, wall pressure and wall shear stress in different vessels.
Description
Technical field
The invention belongs to biomedicine and observation and control technology field, it relates to a kind of extracorporeal blood flow dynamic property test device.
Background technology
Shape of blood vessel and the diameter at each position of human body are not quite similar, same individuality also may change at different ages stage blood vessel diameter, if blood vessel generation focus is such as cardiovascular disorder etc., blood vessel also may be caused to change, the blood flow state of blood vessel also will change thereupon, Hydrodynamic character parameter can characterize blood circumstance, and in human blood circulatory system, main hemodynamic parameter has: blood flow rate, boundary shear stress, wall pressure etc. Wherein, blood flow rate, boundary shear stress and wall pressure characterize volume of blood flow, resistance of blood flow and sign blood pressure respectively.
Directly vascular flow dynamics parameter being tested in human body, experimental situation and condition are harsh, it is difficult to realize. Compared with body build-in test, vitro test system strong operability, controllability height, be applied to modern biomedical research field and clinical medicine inspection. Extracorporeal blood flow dynamic property test device utilizes fluid similarity principle, simulation blood of human body mobility status, and by observation and control technology means, obtains the dynamics parameter of simulation blood flow.
Blood flow has its feature, realize extracorporeal blood flow test, set up a set of extracorporeal blood flow dynamic characterization measurement system, need to possess simulated blood vessel and constant pulsed analog blood flow, peristaltic pump can provide the simulation of heartbeat, utilize resilient material can prepare simulated blood vessel by Modern Manufacturing Technology, by technology such as data gathering and particle test the speed, obtain the Hydrodynamic character parameter of simulate blood.
Summary of the invention
It is an object of the invention to provide a kind of extracorporeal blood flow dynamic property test device, it can provide constant simulation pulsatile blood flow, possesses Hydrodynamic character parameter test system, the Hydrodynamic character parameter in different blood vessel can be tested, such as blood flow rate, wall pressure, wall face shearing stress etc.
The present invention is achieved through the following technical solutions.
A kind of extracorporeal blood flow kinetics dynamic property test device of the present invention, comprises thermostatically controlled tank (1), peristaltic pump (2), silica gel hose (4), the micro-velocity-measuring system of noncontact formula (7), pressure transmitter (11), test zone transparent elastic flexible pipe (8) etc. Thermostatically controlled tank (1) is connected by pipeline, and form closed loop, thermostatically controlled tank (1) is built with the simulate blood (2) containing trace particle, the outlet of thermostatically controlled tank (1) is through silica gel hose (4) through peristaltic pump (3), then district's transparent elastic flexible pipe (8) is connected with the entrance of thermostatically controlled tank (1) after tested; The front and back of test zone, silica gel hose (4) and transparent elastic flexible pipe (8) junction, test zone are separately installed with valve one (5) and valve two (10), and test zone transparent elastic flexible pipe (8) is connected with silica gel hose (4) by test zone entrance silica gel joint (6) and outlet silica gel joint (9). The test position of test zone transparent elastic flexible pipe (8) is provided with pressure transmitter (11), for measuring the wall pressure of test zone transparent elastic flexible pipe (8), realizes data gathering by high-speed data acquisition card (13) and computer (16); The test section of test zone transparent elastic flexible pipe (8) is also provided with the micro-velocity-measuring system of noncontact formula (7), is used for the particle picture caught in transparent elastic flexible pipe (8) test section of test zone. The micro-velocity-measuring system (7) of wherein noncontact formula is made up of industry high speed camera (21), industrial microscope head (22), annular LED light source (23). It is accurate thread between industry high speed camera (21), industrial microscope head (22), annular LED light source (23) to connect. When surveying wall pressure, test zone transparent elastic flexible pipe (8) of micropore is installed, when surveying blood flow rate, then test zone transparent elastic flexible pipe (8) of pore-free is installed.
Described thermostatically controlled tank (1) temperature, by artificial setting, makes simulate blood temperature remain in the actual normal temperature range of blood, the digital display meter displays temperature of thermostatically controlled tank (1). The speed adjustment of described peristaltic pump (3) can also regulate by outer control interface mode by Non-follow control automatically, speed adjustable range is 60 ~ 100r/min, the pump line bed of silica gel hose (4) between the pump head rotor and frame of peristaltic pump (3) passes, and the diameter of silica gel hose (4) can experimentally need to ask and selects.
Described test zone transparent elastic flexible pipe (8) is as simulated blood vessel, it is fixed in white liner plate (18), liner plate should have certain intensity, it is enough to bear the weight of put instrument, test zone transparent elastic flexible pipe (8) can mount and dismount according to demand, test zone transparent elastic flexible pipe (8) possesses good elasticity and erosion resistance, and light transmission is good, does not affect flow field and observes. When surveying wall pressure, installing the transparent elastic flexible pipe with micropore, micropore mates mutually with pressure transmitter probe, and micropore can be arranged on the optional position of transparent elastic flexible pipe test zone, when surveying blood flow rate, installs the transparent elastic flexible pipe of pore-free.
Described test zone entrance silica gel joint (6) and outlet silica gel joint (9) can be installed as requested and replace, but they need to mate mutually with silica gel hose (4) and test zone transparent elastic flexible pipe (8) according to test condition.
Described simulate blood is PSB simulated body fluid, is transparent operation medium, has the ionic environment similar to blood of human body and close kinematic viscosity.
Described pressure transmitter (11) its sensor sensitivity is very high, has certain intensity, and diameter is micron dimension, mates mutually with the micropore of transparent elastic flexible pipe test zone, no leakage.The survey sensor of other parameters is also can be replaced according to test demand.
Trace particle diameter in described simulate blood can be low to moderate several microns, has visual preferably and flowing followability.
The described micro-velocity-measuring system of noncontact formula (7) can catch particle picture clearly, and it is made up of industry high speed camera (21), industrial microscope head (22), annular LED light source (23) and fixing support (24). Described industry high speed camera (21) is high frame per second camera, and industrial microscope head (22) is powerful microscope, and annular LED light source (23) light intensity is stable, anti-interference, no-reflection, and brightness is adjustable. Fixing support (24) is adjustable and handiness good.
The useful effect of the present invention.
1) test set of the present invention simulates beating of heart by the wriggling function of peristaltic pump, and control peristaltic pump, to the extruding of silica gel hose, produces constant pulsating fluid, can simulated blood vessel inner blood flow state effectively; The selection of test zone transparent elastic flexible pipe has certain handiness, can be made into the simulated blood vessel of desired shape, diameter according to test request.
2) test set of the present invention can obtain Hydrodynamic character parameter in simulated blood vessel, adopts pressure transmitter can measure the wall pressure of simulated blood vessel; Adopt the micro-velocity-measuring system of noncontact formula to obtain particle picture in simulated blood vessel, carry out analyzing and processing by the poster processing soft stream field data, obtain the information such as Ink vessel transfusing blood flow rate, wall face shearing stress and wall pressure.
3) test set of the present invention also can test other hemodynamic parameter, just can survey volume of blood flow etc. as pressure transmitter is replaced by flow sensor.
Accompanying drawing explanation
Fig. 1 is the extracorporeal blood flow dynamic property test device schematic diagram of the present invention.
Fig. 2 is the peristaltic pump in the extracorporeal blood flow dynamic property test device of the present invention and pump header structure schematic diagram.
Fig. 3 is the test zone transparent elastic flexible pipe schematic diagram in the extracorporeal blood flow dynamic property test device of the present invention.
Fig. 4 is the micro-velocity-measuring system schematic diagram of the noncontact formula in the extracorporeal blood flow dynamic property test device of the present invention.
In Fig. 1 ~ 4: 1 is thermostatically controlled tank, 2 is the simulate blood containing trace particle, 3 is peristaltic pump, 4 is silica gel hose, 5 is valve one, 6 is test zone entrance silica gel joint, 7 is the micro-velocity-measuring system of noncontact formula, 8 is test zone transparent elastic flexible pipe, 9 is test zone outlet silica gel joint, 10 is valve two, 11 is pressure transmitter, 12 is pressure sensor data communication line, 13 is high-speed data acquisition card, 14 is communication line, 15 is computer, 16 is industry high speed camera communication line, 17 is communication line, 18 is white liner plate, 19 is Wriggling Pump Head frame, 20 is Wriggling Pump Head rotor, 21 is industrial camera, 22 is industrial microscope head, 23 is annular LED light source, 24 is fixing support.
Embodiment
Below in conjunction with accompanying drawing, the specific embodiment of the invention is described in detail.
See Fig. 1, the extracorporeal blood flow dynamic property test device of the present invention comprises thermostatically controlled tank 1, peristaltic pump 3, silica gel hose 4, the micro-velocity-measuring system 7 of noncontact formula, test zone transparent elastic flexible pipe 8, pressure transmitter 11. The pipeline of whole device is the mode connected like this: silica gel hose 4 is connected with thermostatically controlled tank 1, its one end is passed the pump head of peristaltic pump 3, is connected with one end of test zone transparent elastic flexible pipe 8 by test zone entrance silica gel joint 6, the other end of test zone transparent elastic flexible pipe 8 exports silica gel joint 9 with test zone and is connected, test zone outlet silica gel joint 9 again the other end with silica gel hose 4 be connected, valve 1, valve 2 10 are installed on the junction of test zone transparent elastic flexible pipe 8 with silicone tube 4 two ends respectively, and last silica gel hose 4 accesses the entrance of thermostatically controlled tank 1.Owing to test zone transparent elastic flexible pipe 8 tube wall is water white transparency curved surface, but not the micro-velocity-measuring system 7 of contact needs to gather stable image clearly, for avoiding pipeline to offset because vibrations produce image, therefore test zone transparent elastic flexible pipe 8 is fixed on white liner plate 18, liner plate 18 is pure white, smooth surface, flow velocity containing the simulate blood 2 of trace particle is characterized by the speed of trace particle, and these speciality of test zone transparent elastic flexible pipe 8 and white liner plate 18 can strengthen the resolving power of the particle picture caught. Installing the test sets such as pressure transmitter, it is ensured that the simulate blood 2 containing trace particle is added thermostatically controlled tank 1 by line seal non-loosening again, first design temperature, automatically enters temperature constant state when being heated to design temperature. Start peristaltic pump 3, formed after pulsating flow until the simulate blood in pipeline, just can carry out the test of correlation parameter.
See Fig. 2, the peristaltic pump 3 used in the present invention can manual regulation rotating speed and turning to, it is possible to by computer by communication line traffic control, digital display meter shows current rotating speed. The Wriggling Pump Head of peristaltic pump 3 is made up of two portions, i.e. Wriggling Pump Head rotor 20 and Wriggling Pump Head frame 19. Pump line bed is then fixed between Wriggling Pump Head rotor 20 and Wriggling Pump Head frame 19, silica gel hose 4 is arranged in pump line bed by test process, compressing with gland, arrange peristaltic pump 2 desired parameters and start, Wriggling Pump Head rotor 19 and silica gel hose 4 interact and produce pulsating fluid. The present invention studies the rule of blood flow in different blood vessel, tests its Hydrodynamic character, by peristaltic pump 3 for whole test set provides constant pulsed analog blood flow, with the heart rate of the tachometer gage traveller on a long journey of peristaltic pump 3. The speed range of the peristaltic pump 3 that the present invention uses is 0 ~ 300r/min, and the normal cardiac rate scope of people is about 60 ~ 100 beats/min, and for making reliable experiment result, in test process, the rotating speed of peristaltic pump 3 is set to fixed value, and this fixed value is normal cardiac rate scope.
See Fig. 3, the extracorporeal blood flow dynamic property test device of the present invention can make different transparent elastic flexible pipes as simulated blood vessel according to test request, such as the test zone transparent elastic flexible pipe schematic diagram that Fig. 3 is different, but the schematic diagram that the test zone transparent elastic flexible pipe in apparatus of the present invention is never only limitted in Fig. 3. In this test set, can preparing the test zone transparent elastic flexible pipe of different shapes and diameter according to test request, mapping software can be used to draw out the simulated blood vessel of required test, recycling precision instrument is made. In test process, when measuring wall pressure by data collecting system, first the test zone transparent elastic flexible pipe having micropore is connected with silicone tube, then pressure transmitter probe is had access to the test zone transparent elastic flexible pipe of micropore, the position measuring wall pressure is not fixed, and micropore can be arranged on any test zone of test zone transparent elastic flexible pipe according to test request; The sensor of access is not limited to pressure transmitter, can be changed to flow sensor etc., with other blood flow parameters such as measuring flows; During the speed of measure analog blood flow, first the transparent elastic flexible pipe of pore-free is connected with silicone tube, then velocity-measuring system is directed at tested region. When changing test zone transparent elastic flexible pipe, should first stopping the running of peristaltic pump, close the valve on silicone tube, anti-fluid flow goes out, and then changes the gangway silica gel joint mated with test zone transparent elastic flexible pipe, last connecting test district transparent elastic flexible pipe.
See Fig. 4, the micro-velocity-measuring system 7 of the noncontact formula in the present invention, comprises industry high speed camera 21, industrial microscope head 22, annular LED light source 23, fixing support 24. the micro-velocity-measuring system 7 of noncontact formula is for testing the mobility status of the simulate blood 2 containing trace particle. test process starts peristaltic pump 3, after simulate blood in pipeline forms pulsating flow, first industry high speed camera 21 is fixed on fixing support 24, it is loaded on industrial microscope head 22, then annular LED light source 23 is fixed on microlens, the region of testing the speed of alignment test zone transparent elastic flexible pipe 8, regulate industrial microscope head 22, annular LED light source 23 brightness and industry high speed camera 21 parameter, until the trace particle in the tested region of transparent elastic flexible pipe is high-visible, again by video capture software trapped particle image, finally by the image control software processes of computer, just velocity of particle is obtained, wall face shearing stress. in addition, also particle picture can be processed, obtain particle flux line chart, in addition, also can observe the distribution situation etc. of particle in simulated blood vessel.
Part silica gel hose in the present invention, pressure transmitter, test zone transparent elastic flexible pipe and the micro-velocity-measuring system of noncontact formula are all placed on white liner plate, to avoid peristaltic pump vibrations and the measurement of other external factor affecting parameters and the resolving power of trapped particle image, asynchronously carry out the measurement of wall pressure and blood flow rate, because the measurement of blood flow rate may be caused interference when wall pressure is tested.
Claims (8)
1. an extracorporeal blood flow dynamic property test device, is characterized in that comprising thermostatically controlled tank (1), peristaltic pump (2), silica gel hose (4), the micro-velocity-measuring system of noncontact formula (7), pressure transmitter (11), test zone transparent elastic flexible pipe (8); Thermostatically controlled tank (1) is connected by pipeline, and form closed loop, thermostatically controlled tank (1) is built with the simulate blood (2) containing trace particle, the outlet of thermostatically controlled tank (1) is through silica gel hose (4) through peristaltic pump (3), then district's transparent elastic flexible pipe (8) is connected with the entrance of thermostatically controlled tank (1) after tested; The front and back of test zone, silica gel hose (4) and transparent elastic flexible pipe (8) junction, test zone are separately installed with valve one (5) and valve two (10), and test zone transparent elastic flexible pipe (8) is connected with silica gel hose (4) by test zone entrance silica gel joint (6) and outlet silica gel joint (9); The test position of test zone transparent elastic flexible pipe (8) is provided with pressure transmitter (11), for measuring the wall pressure of test zone transparent elastic flexible pipe (8), realizes data gathering by high-speed data acquisition card (13) and computer (16); The test section of test zone transparent elastic flexible pipe (8) is also provided with the micro-velocity-measuring system of noncontact formula (7), is used for the particle picture caught in transparent elastic flexible pipe (8) test section of test zone; The micro-velocity-measuring system (7) of wherein noncontact formula is made up of industry high speed camera (21), industrial microscope head (22), annular LED light source (23); It is accurate thread between industry high speed camera (21), industrial microscope head (22), annular LED light source (23) to connect; When surveying wall pressure, test zone transparent elastic flexible pipe (8) of micropore is installed, when surveying blood flow rate, then test zone transparent elastic flexible pipe (8) of pore-free is installed.
2. extracorporeal blood flow dynamic property test device according to claim 1, it is characterized in that described thermostatically controlled tank (1) temperature is by artificial setting, simulate blood temperature is made to remain in the actual normal temperature range of blood, the digital display meter displays temperature of thermostatically controlled tank (1);The speed adjustment of described peristaltic pump (3) can also regulate by outer control interface mode by Non-follow control automatically, speed adjustable range is 60 ~ 100r/min, the pump line bed of silica gel hose (4) between the pump head rotor and frame of peristaltic pump (3) passes, and the diameter of silica gel hose (4) can experimentally need to ask and selects.
3. extracorporeal blood flow dynamic property test device according to claim 1, it is characterized in that described test zone transparent elastic flexible pipe (8) is as simulated blood vessel, it is fixed in white liner plate (18), liner plate should have certain intensity, the weight being enough to bear put instrument, test zone transparent elastic flexible pipe (8) can mount and dismount according to demand, and test zone transparent elastic flexible pipe (8) possesses good elasticity and erosion resistance, and light transmission is good, does not affect flow field and observe; When surveying wall pressure, installing the transparent elastic flexible pipe with micropore, micropore mates mutually with pressure transmitter probe, and micropore can be arranged on the optional position of transparent elastic flexible pipe test zone, when surveying blood flow rate, installs the transparent elastic flexible pipe of pore-free.
4. extracorporeal blood flow dynamic property test device according to claim 1, it is characterized in that described test zone entrance silica gel joint (6) and outlet silica gel joint (9) can be installed as requested and replace, but they need to mate mutually with silica gel hose (4) and test zone transparent elastic flexible pipe (8) according to test condition.
5. extracorporeal blood flow dynamic property test device according to claim 1, is characterized in that described simulate blood is PSB simulated body fluid, is transparent operation medium, have the ionic environment similar to blood of human body and close kinematic viscosity.
6. extracorporeal blood flow dynamic property test device according to claim 1, it is characterized in that described pressure transmitter (11) its sensor sensitivity is very high, have certain intensity, diameter is micron dimension, mate mutually with the micropore of transparent elastic flexible pipe test zone, no leakage; The survey sensor of other parameters is also can be replaced according to test demand.
7. extracorporeal blood flow dynamic property test device according to claim 1, the trace particle diameter that it is characterized in that in described simulate blood can be low to moderate several microns, has visual preferably and flowing followability.
8. extracorporeal blood flow dynamic property test device according to claim 1, it is characterized in that the described micro-velocity-measuring system of noncontact formula (7) can catch particle picture clearly, it is made up of industry high speed camera (21), industrial microscope head (22), annular LED light source (23) and fixing support (24); Described industry high speed camera (21) is high frame per second camera, and industrial microscope head (22) is powerful microscope, and annular LED light source (23) light intensity is stable, anti-interference, no-reflection, and brightness is adjustable; Fixing support (24) is adjustable and handiness good.
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| CN107764701A (en) * | 2017-10-19 | 2018-03-06 | 中南大学 | It is a kind of to analyze experimental provision and experimental method of the shear stress flow field particle with fluidity |
| CN107764701B (en) * | 2017-10-19 | 2019-08-13 | 中南大学 | It is a kind of analysis shear stress flow field particle with fluidity experimental provision and experimental method |
| CN108062882A (en) * | 2018-02-06 | 2018-05-22 | 西安迈格纳特医疗科技有限公司 | A kind of vascular suture quality testing test operation platform |
| CN108062882B (en) * | 2018-02-06 | 2024-02-27 | 西安迈格纳特医疗科技有限公司 | Vascular suturing quality detection test operation table |
| CN110192865A (en) * | 2018-02-27 | 2019-09-03 | 西诺嘉医药有限公司 | For testing the artificial tissue device of Noninvasive biological parameter measurement device |
| CN109036062A (en) * | 2018-09-07 | 2018-12-18 | 合肥安尔瑞科学仪器制造有限公司 | A kind of vasopressors simulation system |
| CN109984732A (en) * | 2019-04-23 | 2019-07-09 | 广东省人民医院(广东省医学科学院) | A set of half interior animal experiment blood compatibility detection system and its application |
| CN112255170A (en) * | 2020-09-24 | 2021-01-22 | 东南大学 | Dynamic measurement system for peripheral strain field of in vitro vascular tissue |
| CN112274128A (en) * | 2020-12-23 | 2021-01-29 | 广州富玛医药科技股份有限公司 | Blood flow measuring device |
| CN112274128B (en) * | 2020-12-23 | 2021-04-02 | 广州富玛医药科技股份有限公司 | Blood flow measuring device |
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