CN104966452A - Multifunctional modularization blood flow dynamics analog device - Google Patents

Multifunctional modularization blood flow dynamics analog device Download PDF

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Publication number
CN104966452A
CN104966452A CN201510415775.XA CN201510415775A CN104966452A CN 104966452 A CN104966452 A CN 104966452A CN 201510415775 A CN201510415775 A CN 201510415775A CN 104966452 A CN104966452 A CN 104966452A
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module
haemodynamics
analogue means
valve
multifunctional modular
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李守彦
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SUZHOU XINBAN TESTING TECHNOLOGY Co Ltd
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SUZHOU XINBAN TESTING TECHNOLOGY Co Ltd
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    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • G09B23/30Anatomical models
    • G09B23/303Anatomical models specially adapted to simulate circulation of bodily fluids

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Abstract

The invention discloses a multifunctional modularization blood flow dynamics analog device. The device comprises a plurality of detachable and assembled modules with different functions. Each module possesses at least one channel. The plurality of modules can be connected with each other through the at least one channel so as to form a fluid of fluency circulation. One module of the plurality of modules is a pump module which is arranged on the fluid and possesses a linear motor. The pump module simulates contraction and diastole of a ventricle through a mode of driving the fluid based on waveform driving. The plurality of modules can be split into many free and independent modules, or be rearranged via different simple sequences or can realize different functions through accessing one or more additional modules. Through at least one channel, mutual connection is achieved and a new fluid is formed. The additional modules possess at least one channel. Each module provides a specific function and the above functions can be integrated into one multifunctional module.

Description

A kind of multifunctional modular haemodynamics analogue means
Technical field
The present invention relates to a kind of medicine equipment to detect, use training, environment simulator, particularly relate to a kind of multifunctional modular haemodynamics analogue means, be mainly used in scientific research, training, displaying consumer products.
Background technology
The research of blood flow flow field problem is significant and using value, medically many experiments and clinical practice, the design of Biomedical Instruments, goods and development, can obtain help from the research of angioaccess flowing, Pulsating Flow simulation system was described as evaluating the instrument of artificial valvular hydrodynamic characteristic in the eighties in 20th century.Also people is had to circulate for various simulate blood afterwards.But existing system only can realize a specific single analog functuion.Such as, pulse simulation apparatus design is used for the test/simulation of the test of surgery valve instead of all-round other types.It is used for the trial of any other application, such as, simulates support transmission, will inevitably need irreversible design alteration and experiment, and often cause the redesign completely of original pulse analogue means.Amendment needs time, expense and professional knowledge, but for most of user, buys or design independent analogue means make cost too expensive so that infeasible for each analog functuion.
At present, a kind of continuable general pulse simulation system need be designed, to perform various types of emulation and test; Simultaneously those skilled in the art can be allowed to be easy to, this analogue means of reversible adjustment, avoid irreversibly destroying its original analog function and various application-specific can being adapted to.
Summary of the invention
For overcoming the deficiencies in the prior art, the object of the present invention is to provide a kind of multifunctional modular haemodynamics analogue means, be intended to use modular construction, realize to carry out the easy free adjustment performance of configurational stabilisation for demand voluntarily, to adapt to detection and the displaying of different product/function.
For achieving the above object, the present invention is achieved through the following technical solutions:
A kind of multifunctional modular haemodynamics analogue means, comprise: the module of the difference in functionality of multiple detachable, assembling, each module has at least one passage, and described multiple module forms mutually the fluid of smooth circulation by least one described expanding channels; Wherein, one in multiple module is the pump module with linear motor disposed thereon, its according to drive waveforms with the contraction and the diastole that drive the mode of described fluid to simulate ventricle; Described multiple module can be split as multiple freedom independently module each other, or again arrange through simple different sequence order, or realize difference in functionality by accessing one or more add-on module, all be interconnected by least one passage described, form a new fluid, wherein, described multiple be two and more than, described add-on module also has at least one passage.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, one of them in described multiple module is can the compliance adjustment module of simulated blood vessel compliance.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, one in described multiple module is the installation module of valve, and it is for installing artificial valve in systems in which to determine flow direction, can need to install according to valve test.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, a damping module that can regulate voluntarily for user in described multiple module, described damping module can be in aggregates with described compliance module group, or independently become a module, and it is for simulating resistance of blood flow.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, one in described multiple module is the liquid molar block for simulating Atria function.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, also comprise multiple general connector, it comprises pipe fitting, pipeline, coupling mechanism, each general connector has a passage, and described general connector is used for connecting two modules in described multiple modules glibly.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, at least one module in wherein said multiple module has second channel, it forms four terminal exhaust openings by intersection two passages, and can close each the terminal exhaust opening in four terminal exhaust openings selectively.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, one in wherein said multiple module is a periphery module, and it divides for imitating or simulate dissection body or dissect subsystem.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, wherein said periphery module is lifting/lowering sustainer module, and it is for simulating the conveying environment through conduit valve delivery or aortic stents.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, wherein said periphery module is an implanted coronary artery model, and it is for simulating the conveying environment of coronary artery bracket.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, described analogue means is also furnished with all or part of water drain valve be made up of transparent material, temperature sensor, pressure transducer, heating rod, flowmeter and microprocessor.
Preferably, described multifunctional modular haemodynamics analogue means, wherein, described analogue means also comprises: simulated lung vascular compliance damping module, simulation vena cave environment under low pressure module, application specific drive waveforms simulation right ventricle Rythmic contractions characteristic power plant module and tricuspid valve, pulmonary valve module.
The using method of described multifunctional modular haemodynamics analogue means, by this analog module, can human organ, subsystem be studied, learn, practise and be demonstrated, the method comprises, the modular pulse analogue means be made up of multiple module is provided, by coupled to each other glibly removably for multiple module be fluid, wherein each module has at least one passage; Each described module is become the smooth fluid circulated by passage and other at least two module assembleds of each module; There is provided and be arranged on a linear motor in described module to drive described fluid, drive described fluid; Described multiple module is split as multiple freedom independently module each other, or again arrange through simple different sequence order, or realize difference in functionality by accessing one or more add-on module, be interconnected by least one passage of described each module, form a new fluid, different to put in order, value volume and range of product reconnects the circulation can simulating other kinds.
Preferably, the using method of described multifunctional modular haemodynamics analogue means, wherein, one of described module comprises a valve seat, described valve seat makes valve within described passage, and described method also comprises employing valve seat to be arranged on valve in described fluid, and wherein said valve is in fluid described in heart valve prosthesis.
Preferably, the using method of described multifunctional modular haemodynamics analogue means, wherein, Connection Step comprises: via general connector, wherein said general connector has a passage, and can be smooth by two model calling in described multiple module together.
Preferably, the using method of described multifunctional modular haemodynamics analogue means, wherein, also comprises: periphery module inserted and smooth be connected to described fluid, wherein said periphery module is used for imitating or simulation dissection tract.
Preferably, the using method of described multifunctional modular haemodynamics analogue means, wherein, described dissection tract is a lifting/lowering sustainer module.
Preferably, the using method of described multifunctional modular haemodynamics analogue means, wherein, described dissection tract is an implanted coronary artery model.
The present invention is a kind of multifunctional modular haemodynamics analogue means, has following beneficial effect:
(1) module of the difference in functionality of multiple detachable assembling is comprised, user can carry out required by simulation test environment by self assemble, general application is through certain arrangement by these modules, make it that there is substantially similar to mankind blood circulation structure, major part module has four or more interface, only have individually two. do not need the interface used can seal with baffle plate, in such equipment, the flow direction of liquid just can be advanced according to the direction contemplated by user.When analogue means comprises simulated lung vascular compliance damping module, simulation vena cave environment under low pressure module, when application specific drive waveforms simulation right ventricle Rythmic contractions characteristic power plant module and tricuspid valve, pulmonary valve module, can be used for the haemodynamics simulating right heart circulation.
(2) core of the present invention is that the different usages of particular module have difference in functionality, and has certain professional knowledge to require to user: the module of one of them specialty can simulate the contraction of ventricle and the pump module of diastole according to drive waveforms; Second professional module be one can the compliance adjustment module of simulated blood vessel compliance; 3rd professional module is the damping module that user can regulate voluntarily; Damping also can independently become a module with compliance module group is in aggregates, and major function is simulation resistance of blood flow; 4th professional module is the installation module of valve, and this module is used for artificial valve (such as bicuspid valve, pulmonary valve, aorta petal etc.) to install in systems in which to determine flow direction, or needs to install according to valve test; The module of last specialty is the liquid molar block of main analog Atria function; Above-mentioned various module provide only a kind of specific function, by change structure, also above-mentioned functions can be integrated among a multifunction module.
(3) for realizing greater functionality, another advantage of this technology to access the add-on module of other types, and user simulates demand according to haemodynamics, designs some modules access whole system in addition; By accessing one or more add-on module, user has the ability to amplify specific human organ, and local or subsystem are convenient to simulation, observes and study; Such as, if user is by coronary sinus model connecting system, just can observe, study and training are carried out implant to coronary sinus and are discharged.
(4) can be connected to each other between all modules, concrete application only may can use a part wherein.Major part module has four or more interface, and only have individually two, do not need the interface used can seal with baffle plate, in such equipment, the flow direction of liquid just can be advanced according to the direction contemplated by user.On the other hand, system is furnished with water drain valve, temperature sensor, pressure transducer, heating rod, flowmeter and microprocessor, and these modules are all or part of to be made up of transparent material, conveniently directly observes.
Accompanying drawing explanation
Fig. 1 is the structural representation of the multifunctional modular haemodynamics analogue means of simulation right heart circulation;
Fig. 2 is Pulsating Flow simulation system vertical view, and the module connecting method in figure connects according to wherein a kind of application process, and wherein modules constitutes a specific flow circuit;
Fig. 3 is the skeleton view of Pulsating Flow simulation system, in figure, the arrangement method of module is different from Fig. 2, the method of attachment that it should be noted that shown by Fig. 2 does not also form a complete circulation, and the end cap at least removing C1 with C2 place just can be connected add-on module to form complete cycle;
Fig. 4 is the skeleton view of pump module;
Fig. 5 is the skeleton view of valve installation module, comprises a demountable valve cylinder, has two mutually perpendicular passages in module, and module shown in figure has four outlets, is non-closed state, adds upper end cover as required during use;
Fig. 6 is the skeleton view of valve installation module, and valve cylinder takes out, and valve cylinder has the installation site of artificial valve;
Fig. 7 is the skeleton view of compliance/damping module;
Fig. 8 is the skeleton view of liquid molar block, is provided with heating rod and temperature sensor above;
Fig. 9 is equipment a kind of block diagram when applying, and two valve installation modules coordinate other module composition loops to simulate cardiovascular hemodynamic function;
Figure 10 is further illustrating periphery module, and this periphery module is an implanted coronary artery model;
In Figure 11 be by the implanted coronary artery model connecting system in Figure 10 after schematic diagram.
Embodiment
Below in conjunction with accompanying drawing, the present invention is described in further detail, can implement according to this with reference to instructions word to make those skilled in the art.
A kind of multifunctional modular haemodynamics analogue means, comprise: the module of the difference in functionality of multiple detachable, assembling, each module has at least one passage, and described multiple module forms mutually the fluid of smooth circulation by least one described expanding channels; Wherein, one in multiple module is the pump module with linear motor disposed thereon, its according to drive waveforms with the contraction and the diastole that drive the mode of described fluid to simulate ventricle; Described multiple module can be split as multiple freedom independently module each other, or again arrange through simple different sequence order, or realize difference in functionality by accessing one or more add-on module, all be interconnected by least one passage described, form a new fluid, wherein, described multiple be two and more than, described add-on module also has at least one passage.
Further, one of them in described multiple module is can the compliance adjustment module of simulated blood vessel compliance.
Further, one in described multiple module is the installation module of valve, and it is for installing artificial valve in systems in which to determine flow direction, can need to install according to valve test.
Further, a damping module that can regulate voluntarily for user in described multiple module, described damping module can be in aggregates with described compliance module group, or independently become a module, and it is for simulating resistance of blood flow.
Further, one in described multiple module is the liquid molar block for simulating Atria function.
Further, also comprise multiple general connector, it comprises pipe fitting, pipeline, coupling mechanism, and each general connector has a passage, and described general connector is used for connecting two modules in described multiple modules glibly.
Further, at least one module in wherein said multiple module has second channel, and it forms four terminal exhaust openings by intersection two passages, and can close each the terminal exhaust opening in four terminal exhaust openings selectively.
Further, one in wherein said multiple module is a periphery module, and it divides for imitating or simulate dissection body or dissect subsystem.
Further, wherein said periphery module is lifting/lowering sustainer module, and it is for simulating the conveying environment through conduit valve delivery or aortic stents.
Further, wherein said periphery module is an implanted coronary artery model, and it is for simulating the conveying environment of coronary artery bracket.
Further, described analogue means is also furnished with all or part of water drain valve be made up of transparent material, temperature sensor, pressure transducer, heating rod, flowmeter and microprocessor, conveniently directly observes.
Further, described analogue means also comprises: simulated lung vascular compliance damping module, simulation vena cave environment under low pressure module, application specific drive waveforms simulation right ventricle Rythmic contractions characteristic power plant module and tricuspid valve, pulmonary valve module.Accompanying drawings 1, can simulate the multifunctional modular haemodynamics of right heart circulation by these modules.
The using method of described multifunctional modular haemodynamics analogue means, by this analog module, can human organ, subsystem be studied, learn, practise and be demonstrated, the method comprises, the modular pulse analogue means be made up of multiple module is provided, by coupled to each other glibly removably for multiple module be fluid, wherein each module has at least one passage; Each described module is become the smooth fluid circulated by passage and other at least two module assembleds of each module; There is provided and be arranged on a linear motor in described module to drive described fluid, drive described fluid; Described multiple module is split as multiple freedom independently module each other, or again arrange through simple different sequence order, or realize difference in functionality by accessing one or more add-on module, be interconnected by least one passage of described each module, form a new fluid, different to put in order, value volume and range of product reconnects the circulation can simulating other kinds.
Further, one of described module comprises a valve seat, and described valve seat makes valve within described passage, and described method also comprise adopt valve seat valve is arranged in described fluid, wherein said valve is in fluid described in heart valve prosthesis.
Further, Connection Step comprises: via general connector, and wherein said general connector has a passage, and can be smooth by two model calling in described multiple module together.
Further, also comprise: periphery module inserted and smooth be connected to described fluid, wherein said periphery module is used for imitating or simulation dissection tract.
Further, described dissection tract is a lifting/lowering sustainer module.
Further, described dissection tract is an implanted coronary artery model, if user is by coronary sinus model connecting system, just can observe, and study and training are carried out implant to coronary sinus and discharged.
" professional module " mentioned in this technology refers to this module is not only work in systems in which as passage.But this does not mean that this module only has a kind of function yet.A kind of professional module can in conjunction with several functions, and such as pump module also can be used as valve installation module simultaneously.
" outlet " in the module mentioned in this technology refers to when not installing end cap, and fluid can from flowing out here.Be referred to as direction that " outlet " is not the circulation of definition fluid but show can as " entrance " or " outlet " when fluid flows through module.
Present technology provides a new method, user simply can be revised or design simulation system by the connection of each module or re-assembly.
Multiduty modularization cardiovascular hemodynamic simulation system 100 is described in Fig. 2.System 100 has multiple module, has a runner in each module at least.These modules are connected to each other and form circulation, make fluid flow through each module.Whole system is put as Fig. 2, and it is simulated aorta lobe that pump module 110 is connected to valve installation module 120(herein, does not show the valve of installation in figure), module 120 is connected to compliance/damping module 130.Module 130 is connected to external module 150, by 150, circulation is divided into three tunnels and enters three compliances/damping module 130P.Three road fluids finally converge into a road and enter liquid molar block 140, and then enter another valve installation module 120(is simulation bicuspid valve herein), then get back to pump module 110.
External module 150 in Fig. 2 represents it is because module 150 can be arbitrary shape and size with picture frame.Module 150 installation site is in the entire system a very crucial aspect.Module 150 is modules of simulation human organ or institutional framework, and by the module of this emulation, user can to human organ, and subsystem carries out studying, learn, practise and demonstrating.
Modules in system 100 is connected by universal joint, and each joint has a through hole, can connect two modules.
These modules shown in Fig. 2 can be dismantled to come and become independently module.Different to put in order, value volume and range of product reconnects the circulation can simulating other kinds.
Be another circulation shown in Fig. 3, wherein some does not connect.Here, pump module is connected to valve installation module 120.Then compliance/damping module 130 is connected to.Be connected to next compliance/damping module 130.Second 130 module covers one of them outlet by end cap C1.Complete overall connection end cap C1 to be taken off, new module can be connected like this.Here can connect external module 150, other any kind module or be only connected into joint and pipeline.Final purpose is that fluid is imported the outlet covered by end cap C2.Here the C2 seen covers an outlet of liquid molar block.Liquid molar block is connected with another valve installation module 120 and is connected to pump module 110.
In discrimination system, the key of flow direction is the direction of valve in valve installation module.Whenever we need to determine that the installation direction of valve is right.
It is the details drawing of pump module 110 shown in Fig. 4.Pump module has linear electric motors 112, and be arranged on the motor cabinet of transparent air-permeable, there is motor cover outside.Motor cabinet is arranged on block 111.Module introduced afterwards has a block substantially, is substantially all rectangle or square.Such profile seems simple after allowing whole system connect, and totally, has rule.
In preferential scheme, block 111 is transparent solid material, such as an organic glass.In alternative scheme, the block of other modules of block 111(is also) shell of a hollow can be comprised, there is pipeline the inside, and miscellaneous part is enclosed in the inside.
In preferred scheme, in the block of transparent material, there is at least one passage.In the diagram, 119, two, a passage is only had to export 112A and 112B.Have threaded hole to be used for fixing end cap or joint on outlet side, the joint F4 such as seen in Fig. 2 and Figure 11, elbow F2, F3 also have pipeline F1.
Joint and each coupling arrangement are designed to general, are to be that user assembles more freely and convenient.Here the general of indication is not identical, can be applicable equally when size changes yet.Can see in Fig. 2 that external module 150 is connected to 3 compliance/damping modules intuitively.These modules are formed by connecting by the pipeline larger than flow diameter.
The compliance shown in Fig. 2/damping module 130P has two outlets joint F4 has been installed, the 4th outlet install be damping adjustment member 137.User can be bored in 138(Fig. 6 by damping adjusting) position regulate runner inner fluid resistance.Short circuit head F4 can connect the pipeline F1 of different lengths.User can with multiple elbow F2 change runner direction, converge fluid or separation of the fluid.Square elbow F2 and three-dimensional elbow F3 is employed in Fig. 2.The joint of various shape and size can be applied in this.Joint shown in Fig. 2 is not meet overall dimension, but the kind of joint enough user carry out various types of connection.
The pipeline F1 seen in Fig. 2 and 11 is straight, bending or diameter is different equally can be applied in this.
These pipelines make whole system become can to bend.System shown in figure is arranged in same plane, if necessary, modules can be put into vertically, tilts, or distance is amplified.Carry out the position relationship of function in human body more realized close to modules.
The threaded hole S drawn in figure is that other fixed forms also can be considered using fixing for screw thread as a kind of fixed form.Such as fastener is fixed or is installed fixing.
The linear electric motors drawn in figure are to-and-fro movements, drive the liquid among runner 119.Piston below motor by diaphragm seal, such piston just can free movement and do not worry liquid can seepage enter piston.Except this method, other encapsulating method also can as alternative mean.
Linear electric motors need a microprocessor or computer to control, not display in figure here.User can carry out the drive waveforms of regulating and controlling motor by microprocessor or computer.Computer system also can gather some features of cardiovascular hemodynamic, such as pressure, temperature, flow velocity etc.These can by pressure transducer, temperature sensor and the flowmeter installed on the system 100.The installation site user of these sensing devices can oneself select according to demand.
Be valve installation module 120 shown in Fig. 5 and 6, wherein have runner 129A and 129B of block 121 and two right-angled intersections.Runner 129A there are two export 122A, 122B; Runner 129B there are two export 122C, 122D.The 129A of runner shown in Fig. 5 is also equipped with valve cylinder 123, can takes out from outlet 122B.In Fig. 6,123A is support, and 123D is artificial valve installation site.123B is the hole relative with the threaded hole of 122B surrounding, is fixed on block 121 by valve cylinder.User can observe valve state operationally by the window 123C on valve cylinder.After valve cylinder installs, outlet 122B is just sealed.
The fixed form of artificial valve has a variety of, it should be noted that regardless of any mode, fluid all will be made to flow through from valve instead of flow through from valve surrounding.
Need to illustrate that valve cylinder is optional, valve can be replaced to reach the effect determining to flow to by the device of other one-way flows.When use instrument carries out artificial valve test, valve cylinder is only a very important part.Because user needs the device of an easy disassembly valve.
Just as said user can select which outlet closed as required before.Time on the position that valve installation module 120 is placed on the upper right corner in as Fig. 2, outlet 122D place needs to cover end cap C.
Compliance function and damping function are combined togather by the module shown in Fig. 7, are referred to as compliance/damping module.Compliance/damping module 130, wherein has runner 139A and 139B of block 131 and two right-angled intersections.Runner 139A there are two export 132A, 132B; Runner 139B there are two export 132C, 132D.Be connected with compliance tank above block 131 to communicate with runner 139B.The use of compliance tank and damping adjustment member is well-known in existing pulsatile flow test field.Here the knob 137 that damping adjustment member has user adjustable can move damping cone 138 to provide suitable resistance by warp-wise.Compliance tank 133 has a lid 134, has installed suitable lid 135 above, and user can regulate the number of air capacity in compliance tank as required.Compliance tank is used for the compliance of simulated blood vessel.
Compliance/damping module 130 in Fig. 7, equally can as the 130P in Fig. 2 and 11, and both functions are the same.Generally speaking, in order to practical function, multiple independently parts in system, may be used.
Compliance tank spoken of above is optional parts, and experimentally compliance tank can remove by object difference.
Be liquid molar block 140 shown in Fig. 8, wherein have block 141 and runner 149.Runner 149 there are two export 142A, 142B and fluid reservoir 143.Bleeder vent 144 is arranged at the top of fluid reservoir.Among runner 149 and fluid reservoir, there is a columniform liquid to hold 145.Temperature sensor 147B and heating rod 147A is installed inside 145.Temperature sensor is connected with microprocessor or computer respectively by cable 147C with 147D with heating rod.Liquid holds by liquid the water drain valve 146B installed on 145 and bleeds off.User can operate cock of water drain 146A and discharge water, and liquid holds bottom and has dewatering orifice 146C.Drip tray 146D is placed with below block.Liquid molar block is connected among whole system by runner 149, is used for simulating the function in atrium.
Fig. 9 shows a kind of assembling mode.It is a kind of cardiovascular hemodynamic analogue means testing artificial valve in Fig. 9.During test, valve is placed in valve installation module 120.
Said that the important part of this technology the subsystem of human body or histoorgan can be amplified for study and training before.Reaching such object just needs access external unit 150 to realize.This external module with special design, also can use existing model.
Figure 10 is further illustrating external module 150.Shown in figure is an existing silica gel model that can have bought.This model is a kind of implanted coronary artery model.Accurate pulmonary vein 151A, aorta ascendens 151D, descending aorta 151E in structure is had, common iliac artery 151B, 151C and atrium 151F in model.Whole model accesses whole system by joint.Just can use other models on this basis.Such as according to the connection in Figure 10 by the model connecting system 100 in Fig. 9.Coronary artery bracket just can be delivered directly in the middle of silica gel model with special instrument by experimenter.Certain help is had for surgical field.
In Figure 11 be by coronary artery model 151 connecting system after schematic diagram.In figure, fluid circular flow is through atrium 151F, enters aorta ascendens 151D, and then descending aorta 151E enters common iliac artery 151B and 151C.Article two, common iliac artery is all connected to compliance/damping module 130P.Finally be back to liquid molar block 140.Like this, user can be just the conveying of valve or coronary artery bracket in the intervention of controlled cardiovascular hemodynamic condition Imitating.
Further discussion external module, this part includes various existing model configuration, such as artery model, vascular pattern, left atrium ventricular model, pulmonary artery model, superior and inferior vena cava model, brachial artery model and radial artery model etc.
A kind of external module is also had to be implanted coronary artery model, for simulating the environment of the conveying of coronary artery bracket.
Just experimental liquid can be added from liquid molar block after whole system has connected.After experiment terminates, detaching equipment again after operating personnel need liquid to discharge.
Mention, the modules in system 100 according to the difference of experiment demand, optionally can use suitable system architecture of arranging out before.But in the kind that can meet or limited.The arrangement of whole system be with the experience of operating personnel and object closely-related.What kind of effect is what kind of specification can play.
The present invention comprises the module of the difference in functionality of multiple detachable assembling, and user can carry out required by simulation test environment by self assemble, general application be by these modules through certain arrangement, make it that there is substantially similar to mankind blood circulation structure.Core of the present invention is that the different usages of particular module have difference in functionality, and has certain professional knowledge to require to user: the module of one of them specialty can simulate the contraction of ventricle and the pump module of diastole according to drive waveforms; Second professional module be one can the compliance adjustment module of simulated blood vessel compliance; 3rd professional module is the damping module that user can regulate voluntarily; Damping also can independently become a module with compliance module group is in aggregates, and major function is simulation resistance of blood flow; 4th professional module is the installation module of valve, and this module is used for artificial valve (such as bicuspid valve, pulmonary valve, aorta petal etc.) to install in systems in which to determine flow direction, or needs to install according to valve test; The module of last specialty is the liquid molar block of main analog Atria function; Above-mentioned various module provide only a kind of specific function, by change structure, also above-mentioned functions can be integrated among a multifunction module.For realizing greater functionality, another advantage of this technology to access the add-on module of other types, and user simulates demand according to haemodynamics, designs some modules access whole system in addition; By accessing one or more add-on module, user has the ability to amplify specific human organ, and local or subsystem are convenient to simulation, observes and study; Such as, if user is by coronary sinus model connecting system, just can observe, study and training are carried out implant to coronary sinus and are discharged.Can be connected to each other between all modules, concrete application only may can use a part wherein.Major part module has four or more structure, and only have individually two, do not need the interface used can seal with baffle plate, in such equipment, the flow direction of liquid just can be advanced according to the direction contemplated by user.On the other hand, system is furnished with water drain valve, temperature sensor, pressure transducer, heating rod, flowmeter and microprocessor, and these modules are all or part of to be made up of transparent material, conveniently directly observes.
Although embodiment of the present invention are open as above, but it is not restricted to listed in instructions and embodiment utilization, it can be applied to various applicable the field of the invention completely, for those skilled in the art, can easily realize other amendment, therefore do not deviating under the universal that claim and equivalency range limit, the present invention is not limited to specific details and illustrates here and the legend described.

Claims (18)

1. a multifunctional modular haemodynamics analogue means, it is characterized in that, comprise: the module of the difference in functionality of multiple detachable, assembling, each module has at least one passage, and described multiple module forms mutually the fluid of smooth circulation by least one described expanding channels; Wherein, one in multiple module is the pump module with linear motor disposed thereon, its according to drive waveforms with the contraction and the diastole that drive the mode of described fluid to simulate ventricle; Described multiple module can be split as multiple freedom independently module each other, or again arrange through simple different sequence order, or realize difference in functionality by accessing one or more add-on module, all be interconnected by least one passage described, form a new fluid, wherein, described multiple be two and more than, described add-on module also has at least one passage.
2. multifunctional modular haemodynamics analogue means as claimed in claim 1, is characterized in that, one of them in described multiple module is can the compliance adjustment module of simulated blood vessel compliance.
3. multifunctional modular haemodynamics analogue means as claimed in claim 1, it is characterized in that, one in described multiple module is the installation module of valve, and it is for installing artificial valve in systems in which to determine flow direction, can need to install according to valve test.
4. multifunctional modular haemodynamics analogue means as claimed in claim 1, it is characterized in that, a damping module that can regulate voluntarily for user in described multiple module, described damping module can be in aggregates with described compliance module group, or independently becoming a module, it is for simulating resistance of blood flow.
5. multifunctional modular haemodynamics analogue means as claimed in claim 1, it is characterized in that, one in described multiple module is the liquid molar block for simulating Atria function.
6. multifunctional modular haemodynamics analogue means as claimed in claim 1, it is characterized in that, also comprise multiple general connector, it comprises pipe fitting, pipeline, coupling mechanism, each general connector has a passage, and described general connector is used for connecting two modules in described multiple modules glibly.
7. multifunctional modular haemodynamics analogue means as claimed in claim 1, it is characterized in that, at least one module in described multiple module has second channel, it forms four terminal exhaust openings by intersection two passages, and can close each the terminal exhaust opening in four terminal exhaust openings selectively.
8. multifunctional modular haemodynamics analogue means as claimed in claim 1, it is characterized in that, one in described multiple module is a periphery module, and it divides for imitating or simulate dissection body or dissect subsystem.
9. multifunctional modular haemodynamics analogue means as claimed in claim 1, it is characterized in that, described periphery module is lifting/lowering sustainer module, and it is for simulating the conveying environment through conduit valve delivery or aortic stents.
10. multifunctional modular haemodynamics analogue means as claimed in claim 1, it is characterized in that, described periphery module is an implanted coronary artery model, and it is for simulating the conveying environment of coronary artery bracket.
11. multifunctional modular haemodynamics analogue means as claimed in claim 1, it is characterized in that, described analogue means is also furnished with all or part of water drain valve be made up of transparent material, temperature sensor, pressure transducer, heating rod, flowmeter and microprocessor.
12. multifunctional modular haemodynamics analogue means as claimed in claim 1, it is characterized in that, described analogue means also comprises: simulated lung vascular compliance damping module, simulation vena cave environment under low pressure module, application specific drive waveforms simulation right ventricle Rythmic contractions characteristic power plant module and tricuspid valve, pulmonary valve module.
The using method of multifunctional modular haemodynamics analogue means described in 13., by this analog module, can the haemodynamics of human organ, subsystem be studied, learns, practises and be demonstrated, the method comprises, the modularization pulsed analog device be made up of multiple module is provided, by coupled to each other glibly removably for multiple module be fluid, wherein each module has at least one passage; Each described module is become the smooth fluid circulated by passage and other at least two module assembleds of each module; There is provided and be arranged on a linear motor in described module to drive described fluid; Described multiple module is split as multiple freedom independently module each other, or again arrange through simple different sequence order, or realize difference in functionality by accessing one or more add-on module, be interconnected by least one passage of described each module, form a new fluid, different to put in order, value volume and range of product reconnects the circulation can simulating other kinds.
The using method of 14. multifunctional modular haemodynamics analogue means as claimed in claim 13, it is characterized in that, one of wherein said module comprises a valve seat, described valve seat makes valve within described passage, and described method also comprises employing valve seat to be arranged on valve in described fluid, and wherein said valve is heart valve prosthesis.
The using method of 15. multifunctional modular haemodynamics analogue means as claimed in claim 13, it is characterized in that, wherein Connection Step comprises: via general connector, wherein said general connector has a passage, and can be smooth by two model calling in described multiple module together.
The using method of 16. multifunctional modular haemodynamics analogue means as claimed in claim 13, it is characterized in that, also comprise: periphery module inserted and smooth be connected to described fluid, wherein said periphery module is used for imitating or simulation dissection tract.
The using method of 17. multifunctional modular haemodynamics analogue means as claimed in claim 16, is characterized in that, described dissection tract is a lifting/lowering sustainer module.
The using method of 18. multifunctional modular haemodynamics analogue means as claimed in claim 17, is characterized in that, described dissection tract is an implanted coronary artery model.
CN201510415775.XA 2015-07-16 2015-07-16 Multifunctional modularization blood flow dynamics analog device Pending CN104966452A (en)

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CN111429787A (en) * 2020-04-07 2020-07-17 中南大学 Artificial blood pump in-vitro simulation circulating system
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Application publication date: 20151007