CN105636453B - 物质混合物 - Google Patents

物质混合物 Download PDF

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Publication number
CN105636453B
CN105636453B CN201480057236.7A CN201480057236A CN105636453B CN 105636453 B CN105636453 B CN 105636453B CN 201480057236 A CN201480057236 A CN 201480057236A CN 105636453 B CN105636453 B CN 105636453B
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CN
China
Prior art keywords
weight
products
mixture
formulation
rebaudioside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201480057236.7A
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English (en)
Chinese (zh)
Other versions
CN105636453A (zh
Inventor
乌维·舍费尔
格哈德·克拉默
杰拉尔德·格劳比茨
托马斯·里斯
雅各布·雷
苏珊娜·佩茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symrise AG
Original Assignee
Symrise AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of CN105636453A publication Critical patent/CN105636453A/zh
Application granted granted Critical
Publication of CN105636453B publication Critical patent/CN105636453B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/06Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/10Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/13Fermented milk preparations; Treatment using microorganisms or enzymes using additives
    • A23C9/1307Milk products or derivatives; Fruit or vegetable juices; Sugars, sugar alcohols, sweeteners; Oligosaccharides; Organic acids or salts thereof or acidifying agents; Flavours, dyes or pigments; Inert or aerosol gases; Carbonation methods
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/152Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/154Milk preparations; Milk powder or milk powder preparations containing additives containing thickening substances, eggs or cereal preparations; Milk gels
    • A23C9/1544Non-acidified gels, e.g. custards, creams, desserts, puddings, shakes or foams, containing eggs or thickening or gelling agents other than sugar; Milk products containing natural or microbial polysaccharides, e.g. cellulose or cellulose derivatives; Milk products containing nutrient fibres
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/42Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/06Chewing gum characterised by the composition containing organic or inorganic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52Adding ingredients
    • A23L2/60Sweeteners
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20Synthetic spices, flavouring agents or condiments
    • A23L27/204Aromatic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/33Artificial sweetening agents containing sugars or derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/33Artificial sweetening agents containing sugars or derivatives
    • A23L27/35Starch hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/33Artificial sweetening agents containing sugars or derivatives
    • A23L27/36Terpene glycosides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/88Taste or flavour enhancing agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L9/00Puddings; Cream substitutes; Preparation or treatment thereof
    • A23L9/10Puddings; Dry powder puddings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Inorganic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Microbiology (AREA)
  • Cosmetics (AREA)
  • Seasonings (AREA)
  • Fats And Perfumes (AREA)
CN201480057236.7A 2013-10-31 2014-10-26 物质混合物 Active CN105636453B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13191008.5 2013-10-31
EP13191008.5A EP2868209B1 (de) 2013-10-31 2013-10-31 Stoffgemische
PCT/EP2014/072928 WO2015062998A1 (en) 2013-10-31 2014-10-26 Mixtures of matter

Publications (2)

Publication Number Publication Date
CN105636453A CN105636453A (zh) 2016-06-01
CN105636453B true CN105636453B (zh) 2019-12-24

Family

ID=49510032

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480057236.7A Active CN105636453B (zh) 2013-10-31 2014-10-26 物质混合物

Country Status (6)

Country Link
US (1) US10251409B2 (enExample)
EP (1) EP2868209B1 (enExample)
JP (1) JP6494611B2 (enExample)
CN (1) CN105636453B (enExample)
ES (1) ES2738355T3 (enExample)
WO (1) WO2015062998A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2966205A1 (en) * 2014-11-17 2016-05-26 Kraft Foods Group Brands Llc Beverage product with potassium sodium tartrate
WO2017071784A1 (de) 2015-10-29 2017-05-04 Symrise Ag Nahrungsmittel (iii)
EP3383200B1 (de) 2015-12-01 2019-11-06 Symrise AG Stoffgemische
ES2818589T3 (es) * 2016-01-19 2021-04-13 Firmenich & Cie Floretina
JP6261834B1 (ja) * 2016-03-18 2018-01-17 サントリーホールディングス株式会社 飲料、飲料の製造方法、及び飲料の香味を改善する方法
WO2017172766A1 (en) * 2016-03-28 2017-10-05 The Coca-Cola Company Sweetness and taste improvement of steviol glycoside or mogroside sweeteners with flavonids
US20190297932A1 (en) * 2016-06-06 2019-10-03 Tate & Lyle Ingredients Americas Llc Glycosylated steviol glycoside compositions and methods of preparing glycosylated steviol glycoside compositions
US11076619B2 (en) * 2016-12-30 2021-08-03 Red Bull Gmbh Sweetening compositions
WO2019096363A1 (de) * 2017-11-14 2019-05-23 Symrise Ag Antimikrobiell wirksame mischungen
WO2020255051A1 (en) * 2019-06-20 2020-12-24 Almendra Pte. Ltd. Fragrance-enhancing compositions
CN114340403A (zh) * 2019-08-23 2022-04-12 三得利控股株式会社 含有瑞鲍迪苷d的水性组合物的制造方法、含有瑞鲍迪苷d的甜味组合物及含有甜味组合物的饮料
WO2021039944A1 (ja) * 2019-08-28 2021-03-04 サントリーホールディングス株式会社 ステビオール配糖体組成物およびステビア植物の乾燥葉からステビオール配糖体組成物を製造する方法
JP2023532520A (ja) * 2020-07-01 2023-07-28 ザ コカ・コーラ カンパニー 味が改善されたアルコール炭酸飲料
KR20230119183A (ko) * 2020-12-17 2023-08-16 지보당 에스아 맛 조절을 위한 조성물 및 방법
JP7735088B2 (ja) * 2021-06-10 2025-09-08 サントリーホールディングス株式会社 甘味料組成物
KR102853724B1 (ko) * 2025-03-06 2025-09-01 고재철 뇌파 조절 효과가 우수한 향료 조성물

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2340719A1 (en) * 2009-12-30 2011-07-06 Symrise AG Aroma composition comprising o-coumaric acid to reduce or suppress undesirable taste impressions of sweeteners

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL149701C (nl) 1965-12-08 1981-05-15 Procter & Gamble Werkwijze voor het bereiden van een tegen tandsteen werkzaam tandverzorgingsmiddel, dat als werkzaam bestanddeel een fosfonzuurderivaat bevat, alsmede gevormd tandverzorgingsmiddel.
DE2224430C3 (de) 1972-05-19 1980-10-09 Henkel Kgaa, 4000 Duesseldorf Zahnsteinbildung verhindernde Mund- und Zahnpflegemittel
DE2343196C3 (de) 1973-08-27 1980-01-10 Henkel Kgaa, 4000 Duesseldorf Aiacycloalkan-2^-diphosphonsäuren oder deren wasserlösliche Salze
US5286500A (en) 1992-03-03 1994-02-15 Wm. Wrigley Jr. Company Wax-free chewing gum base
WO2007014879A1 (en) 2005-07-27 2007-02-08 Symrise Gmbh & Co. Kg Use of hesperetin for enhancing the sweet taste
EP2368442B1 (en) 2005-07-27 2014-12-17 Symrise AG Use of hesperetin for enhancing the sweet taste
US8318459B2 (en) 2011-02-17 2012-11-27 Purecircle Usa Glucosyl stevia composition
US8323716B2 (en) * 2005-10-11 2012-12-04 Purecircle Sdn Bhd Sweetner and use
US8962058B2 (en) * 2005-11-23 2015-02-24 The Coca-Cola Company High-potency sweetener composition with antioxidant and compositions sweetened therewith
US8778987B2 (en) * 2007-03-13 2014-07-15 Symrise Ag Use of 4-hydroxychalcone derivatives for masking an unpleasant taste
JP4892710B2 (ja) 2007-04-27 2012-03-07 東洋精糖株式会社 高甘味度甘味料
JP5258783B2 (ja) * 2007-11-12 2013-08-07 三栄源エフ・エフ・アイ株式会社 ステビア抽出物の甘味質改善
EP2220945B1 (en) * 2008-12-11 2013-03-27 Symrise AG Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners
EP2253226B1 (de) 2009-05-15 2015-07-15 Leibniz-Institut für Pflanzenbiochemie (IPB) Verwendung von Hydroxyflavan-Derivaten zur Geschmacksmodifizierung
US10624372B2 (en) * 2009-08-28 2020-04-21 Symrise Ag Reduced-sweetener products, flavoring mixtures for said reduced-sweetener products and process for the production of products of this type
US8574656B2 (en) * 2009-10-15 2013-11-05 Purecircle Sdn Bhd High-purity Rebaudioside D and low-calorie fruit juice containing the same
EP2340729A1 (en) 2009-12-30 2011-07-06 Philip Morris Products S.A. An improved heater for an electrically heated aerosol generating system
EP2359702B1 (en) * 2010-01-22 2014-06-04 Symrise AG Solubilization agent for solubilizing polyphenols, flavonoids and/or diterpenoid glucosides
EP2353403B1 (de) 2010-02-01 2012-07-11 Symrise AG Verwendung von 1-(2,4-Dihydroxy-phenyl)-3-(3-hydroxy-4-methoxy-phenyl)-propan-1-on
CN106107406B (zh) * 2010-08-12 2020-06-09 弗门尼舍公司 提高甜味增强剂的稳定性的方法和包含稳定的甜味增强剂的组合物
US20140010917A1 (en) 2011-03-22 2014-01-09 Purecircle Usa Inc. Glucosylated steviol glycosides composition as a taste and flavor enhancer
EP2529633B1 (de) * 2011-06-01 2014-08-06 Symrise AG Oral konsumierbare Zubereitungen umfassend bestimmte süß schmeckende Triterpene und Triterpenglycoside
EP2570036B1 (de) 2011-09-15 2014-06-18 Symrise AG Verwendung bestimmter Neoflavonoide zur Verstärkung und/oder Erzeugung eines süßen sensorischen Eindruckes
EP3735841A1 (en) 2011-12-19 2020-11-11 PureCircle SDN BHD Methods for purifying steviol glycosides and uses of the same
EP2628398B1 (de) * 2012-02-19 2016-09-07 Symrise AG Stoffgemische

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2340719A1 (en) * 2009-12-30 2011-07-06 Symrise AG Aroma composition comprising o-coumaric acid to reduce or suppress undesirable taste impressions of sweeteners

Also Published As

Publication number Publication date
JP6494611B2 (ja) 2019-04-03
US10251409B2 (en) 2019-04-09
ES2738355T3 (es) 2020-01-22
EP2868209A1 (de) 2015-05-06
CN105636453A (zh) 2016-06-01
JP2016537317A (ja) 2016-12-01
EP2868209B1 (de) 2019-04-03
US20160295892A1 (en) 2016-10-13
WO2015062998A1 (en) 2015-05-07

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