CN105596249B - A kind of Chinese medical extract of anti-red blood silk and its application in skin care item - Google Patents
A kind of Chinese medical extract of anti-red blood silk and its application in skin care item Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/748—Oldenlandia or Hedyotis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
The invention discloses a kind of Chinese medical extract of anti-red blood silk and its applications in skin care item.The preparation process of the Chinese medical extract is：1) Rabdosia rubescens, oldenlandia diffusa, Radix Astragali are crushed to 60~100 mesh respectively, then the weight and are uniformly mixed, obtain Chinese medicine composition；2) it is that 30~70% ethyl alcohol extract to obtain extracting solution percent by volume to be added in above-mentioned Chinese medicine composition, and the bulking value ratio g/mL of the Chinese medicine composition and ethyl alcohol is 1: 10~1: 20；3) extracting solution for preparing step 2) stands 1~4 hour, and after the filtering of 100~200 mesh, for vacuum filtration to clarifying, to ethyl alcohol is free of, using 90~100 DEG C of sterilizings under normal pressure, Chinese medical extract is finally prepared in decompression rotary evaporation.Using Chinese herbal medicine extract as the additive of beauty and skin care cosmetics, has the characteristics that efficacy stability, lasting, small to skin action temperature and irritation, safe, significant in efficacy.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, specifically a kind of Chinese medicinal skin care combination with anti-red blood silk effect
The skincare product of object and the Chinese medicinal skin care formulation application that is prepared by the skin care compositions in cosmetic field.
Background technology
In recent years, the related dermal problem that skin sensitivity caused is increasingly becoming the heat of cosmetic industry and medical industries research
Point.Wherein, the red blood silk that facial telangiectasias causes not only seriously affects patient's beauty, is also resulted in very to the psychology of patient
Big burden.
Red blood trace on face, medically also known as facial telangiectasias, that is, the elasticity of capillary wall reduce, crisp
Property enhancing, the non-uniform expansion of continuous vessel even ruptures, and causes skin of face general red, the blood capillary of the visible expansion of naked eyes
Pipe is often accompanied by red or aubergine plaque-like, dotted, linear or starlike etc. phenomenon, referred to as telangiectasia.Form face
The reason of red blood silk, complexity was various, can substantially be divided into primary and secondary, primary telangiectasis is congenital capillary
Caused by angiokinesis defect；Common secondary telangiectasis is because being divided into 5 kinds：High altitude weather, hormonal dependent hair
Thin blood vessel dilatation, physical factor stimulation, chemical factor stimulation, locally or systemically disease complication.
Although it is several to mostly use liquid nitrogen cryotherapy, photon therapy, laser therapy, drug smearing treatment etc. currently on the market
Method treats red blood silk, but the drawbacks such as generally existing curative effect is not thorough, the surface of a wound is big, stimulation is larger.
With the continuous improvement of social development living standards of the people, quality and performance requirement for cosmetics are also increasingly
It is high.It is desirable to occur it is a series of not only had anti-red blood silk effect but also be harmful to human health, and with beauty and health care functions
Functional cosmetics.
Invention content
To solve the above problems, the purpose of the present invention is to provide a kind of, the Chinese medicinal skin care with anti-red blood silk effect combines
Object, using Chinese herbal medicine extract as the additive of beauty and skin care cosmetics, have efficacy stability, persistently, to skin action temperature
The features such as small, safe, significant in efficacy with irritation.
In order to achieve the object of the present invention, the specific technical solution of the present invention is as follows：
A kind of Chinese medical extract of anti-red blood silk, the bulk pharmaceutical chemicals matched by following weight parts are made：
40~60 parts of Rabdosia rubescens, 10~30 parts of oldenlandia diffusa, 10~30 parts of Radix Astragali.
The Chinese medical extract of the anti-red blood silk is prepared according to following processing step：
1) Rabdosia rubescens, oldenlandia diffusa, Radix Astragali are crushed to 60~100 mesh respectively, then matched according to the parts by weight
Than being uniformly mixed, Chinese medicine composition is obtained；
2) it is that 30~70% ethyl alcohol extract to obtain extracting solution percent by volume to be added in above-mentioned Chinese medicine composition, described
The bulking value ratio g/mL of Chinese medicine composition and ethyl alcohol is 1: 10~1: 20；
3) extracting solution for preparing step 2) stands 1~4 hour, and after the filtering of 100~200 mesh, vacuum filtration subtracts to clarifying
It presses rotary evaporation to ethyl alcohol is free of, using 90~100 DEG C of sterilizings under normal pressure, Chinese medical extract is finally prepared.
Application of the Chinese medical extract of above-mentioned anti-red blood silk in skin care item, the skin care item include：Chinese medical extract；And
90~99.9% skin care field customary adjuvant.
Application of the Chinese medical extract of the anti-red blood silk in skin care item, by weight percentage, the Chinese medicine carries
Object is taken to account for the 0.1%~10% of skin care item total amount.
Application of the Chinese medical extract of the anti-red blood silk in skin care item, by weight percentage, the Chinese medicine carries
Object is taken to account for the 0.5%~5% of skin care item total amount.
Application of the Chinese medical extract of the anti-red blood silk in skin care item, the customary adjuvant includes surface-active
Agent, thickener, conditioner, moisturizer, preservative, chelating agent, essence, deionized water etc..
Application of the Chinese medical extract of the anti-red blood silk in skin care item, the skin care item can be made into toner, soft
Skin water, firming lotion, nutrition toner, nourishing cream, massage cream, essence, eye cream, eye essence, cleansing cream, skin cleaning foam, clean skin
The various dosage forms such as water, facial mask, muffin, body dew, body frost, body oil, body lotion and body essence.
The present invention has the advantages that：
1, the present invention provides the extracted obtained Chinese medical extract of Chinese medicine composition and has promotion microcirculation well, eliminates
The effect of inflammatory factor, and preparation method is easy, the skin care formulation being prepared using it, products obtained therefrom is green safe, effect
Significantly, it easily absorbs.
2, after tested, Chinese medical extract of the present invention itself, which has, inhibits thrombin activity, improves blood microcirculation.
3, it is demonstrated experimentally that face cream preparation of the present invention is using after 28 days, tested region red blood silk declines, and to skin without
Stimulation.Therefore can be added in cosmetics as plant functional additive, especially for the red blood silk of secondary generation, making
For best results in the skin cares such as inflammation caused by skin microcirculation is unsmooth and chemical factor stimulation.
Description of the drawings
Fig. 1 is that the anti-red blood silk Chinese herbal medicine extract of embodiment 1 inhibits the design sketch of thrombin activity.
Fig. 2 is that the anti-red blood silk Chinese herbal medicine extract of embodiment 2 inhibits the design sketch of thrombin activity.
Fig. 3 is that the anti-red blood silk Chinese herbal medicine extract of embodiment 3 inhibits the design sketch of thrombin activity.
Specific implementation mode
The following example further illustrates the various embodiments in the scope of the invention.These embodiments are merely to say
Improving eyesight and provide, be not used to limit the present invention, can be with because without departing from the spirit and scope of the present invention
Many variations are carried out to the present invention.
Medicinal material used in the present embodiment is purchased from China Medicament Group Corp., meets 2005 editions marks of the People's Republic of China's pharmacopeia
It is accurate.
For the present invention based on China's Traditional Chinese Medicine theory, skin health is objective, the skin care compositions be from
Extract isolated in Rabdosia rubescens, oldenlandia diffusa, three taste Chinese medicine of Radix Astragali, the effect of three taste Chinese medicine is described as follows：
Rabdosia rubescens：It is bitter in taste, sweet, be slightly cold.Rabdosia rubescens has good heat-clearing poison, promoting blood circulation and stopping pain, antibacterial, antitumor action；
Oldenlandia diffusa：It is patent medicine bitter, light, it is cold in nature.Primary efficacy is clearing heat and detoxicating, medicinal powder for relieving pain knot, promoting urination and removing dampness.It is outstanding kind
Treat various types inflammation；
Radix Astragali：The dry root of legume astragalus mongolicus or Astragalus membranacus.Sweet in flavor, gas tepor, gas is thin and taste is dense, and can rise can
Drop, the yang aspect of yang are nontoxic.Special tonifying Qi, function is a lot of, and its only effect person, is enriching blood especially.Active ingredient has Astrageloside
With triterpene compound and polysaccharose substance, amino acids, the flavones such as Kaempferol, Quercetin and flavones, Radix Astragali can make
The haemocyte quantity of reduction restores normal, increases anti-anoxia ability, prevents lipid peroxidation, improves renal function, prevents glycogen
Original is reduced, the effect of anti-aging, is also enhanced body nospecific immunity and is enhanced the function of Abwehrkraft des Koepers.Huang in Radix Astragali
Stilbene saponins and isoflavone compound improve significantly to the deformability for hatching red blood cell.
Raw material of skin care articles of the present invention is known in the art raw material.
The preparation of the 1 anti-red blood silk Chinese medical extract of the present invention of embodiment
Rabdosia rubescens, oldenlandia diffusa, Radix Astragali are crushed to 60 mesh respectively to be uniformly mixed, Rabdosia rubescens 60g, oldenlandia diffusa
20g, Radix Astragali 20g, are added 50% ethanol water of percent by volume, and the bulking value ratio g/mL of Chinese medicine composition and ethyl alcohol is
1: 15, refluxing extraction 1.5 hours, temperature is 70 DEG C, extraction time 2 times；Stop heating, merges filtrate twice, it is small that room temperature stands 2
When, the filtering of 200 mesh；600 mesh filter paper filter under vacuum condition, vacuum degree 0.095MPa, after depressurizing rotary evaporation to no ethyl alcohol
As anti-red blood silk Chinese medical extract, it is 6.36 that its pH value is measured at 25 DEG C, and conductivity is 3963 μ s/cm, and solid content is
5.9%.
The preparation of the 2 anti-red blood silk Chinese medical extract of the present invention of embodiment
Rabdosia rubescens, oldenlandia diffusa, Radix Astragali are crushed to 80 mesh respectively to be uniformly mixed, wherein Rabdosia rubescens 40g, oldenlandia
Careless 30g, Radix Astragali 30g, addition percent by volume are 70% ethanol water, the bulking value ratio g/ of Chinese medicine composition and ethyl alcohol
ML is 1: 10, refluxing extraction 2 hours, and temperature is 70 DEG C, and extraction time is 3 times；Stop heating, room temperature stands 3 hours, 200 mesh
Filtering；600 mesh filter paper filter under vacuum condition, vacuum degree 0.095MPa, are anti-red after decompression rotary evaporation to no ethyl alcohol
Trace of blood Chinese medical extract, it is 6.34 that its pH value is measured at 25 DEG C, and conductivity is 3870 μ s/cm, solid content 6.0%.
The preparation of the 3 anti-red blood silk Chinese medical extract of the present invention of embodiment
Rabdosia rubescens, oldenlandia diffusa, Radix Astragali are crushed to 100 mesh respectively first to be uniformly mixed, wherein Rabdosia rubescens 50g, in vain
Flower HERBA HEDYOTIS DIFFUSAE 25g, Radix Astragali 25g, addition percent by volume are 60% ethanol water, the bulking value of Chinese medicine composition and ethyl alcohol
Ratio g/mL is 1: 20, refluxing extraction 2 hours, and temperature is 70 DEG C, and extraction time is 2 times；Stopping heating, room temperature stands 4 hours,
200 mesh filter；600 mesh filter paper filter under vacuum condition, vacuum degree 0.095MPa, are after depressurizing rotary evaporation to no ethyl alcohol
Livid ring around eye of dispelling Chinese medical extract, it is 6.46 that its pH value is measured at 25 DEG C, and conductivity is 4896 μ s/cm, and solid content is
6.3%.
The preparation of the 4 anti-red blood silk Chinese medical extract of the present invention of embodiment
Rabdosia rubescens, oldenlandia diffusa, Radix Astragali are crushed to 100 mesh respectively first to be uniformly mixed, wherein Rabdosia rubescens 50g, in vain
Flower HERBA HEDYOTIS DIFFUSAE 25g, Radix Astragali 25g, addition percent by volume are 30% ethanol water, the bulking value of Chinese medicine composition and ethyl alcohol
Ratio g/mL is 1: 20, refluxing extraction 2 hours, and temperature is 70 DEG C, and extraction time is 3 times；Stopping heating, room temperature stands 4 hours,
200 mesh filter；600 mesh filter paper filter under vacuum condition, vacuum degree 0.095MPa, are after depressurizing rotary evaporation to no ethyl alcohol
Livid ring around eye of dispelling Chinese medical extract, it is 6.39 that its pH value is measured at 25 DEG C, and conductivity is 4039 μ s/cm, and solid content is
5.8%.
Effete test embodiment 1
Efficacy assessments are carried out to 1 moderate resistance red blood silk Chinese medical extract of embodiment：
When secondary telangiectasis causes blood viscosity to increase, critical capilary radius increases, and micro- resistance of blood flow increases
Add, micro- stasis of blood stream, intravascular blood flow slows down, vascular injury, endovascular platelet activation, and thrombin activity increases induction blood
Platelet aggregation enhances, and fibrin ferment is also catalytically decomposed fibrinogen and becomes fibroblast cells and promote blood clotting so that micro-
Endovascular velocity of blood flow further slows down, is detained, and influences blood viscosity and critical capillary radius, hence it is evident that increase micro- blood flow
Resistance, or even the activity for causing capilary to block, therefore testing fibrin ferment can reflect whether determinand has anti-red blood silk
Effect.
Inhibit thrombin activity assay：
Using fibrinogen as substrate, it is fabricated to fibrinogen tablet with agarose and fibrinogen, with solidifying
The hemase standard items diffusion reaction on the tablet respectively makes corresponding standard curve and regression curve, and inhibits to sample
Thrombin activity quantitative determines.
1) configuration of 2% agarose：The agarose of 1.00g is weighed, 50ml distilled water, ebuillition of heated to dissolving is added；
2) configuration of 0.2% fibrinogen：The fibrinogen of 0.05g is weighed, 50ml 0.1mol/L are added
PH7.4 phosphate buffers, 30 DEG C of dissolvings；
3) fibrinogen flat panel production：2% agarose solution is cooled to 50-60 DEG C, with 0.1% fibrinogen with 1:
1 volume ratio mixing fills plate in plate, and thickness is about 2mm, fibrinogen tablet is made after cooling, by 1.6cm's
Spacing is punched, and aperture is about 4mm.
4) dilution 28,14,7,3.5, the thrombin standard product of 1.75U/mL are loaded in plate hole, 20 μ L are loaded per hole,
In 37 DEG C of constant temperature diffusion reaction 8-10h after sealing.Each reacting hole precipitation loop diameter (mm) size is measured, with each thrombin standard product
It is ordinate that reacting hole, which precipitates loop diameter, and thrombin activity is that abscissa draws standard curve, and carries out equation regression calculating.
5) by the sample solution of various concentration 1,3,5,7,9% and 0.05mol/L PBS solutions 1：After 1 mixing, with 7U/mL
Fibrin ferment takes 20 μ L samples holes after being mixed with 1: 1 volume ratio, the fibrin ferment of 20 μ L, 3.5U/mL is added in blank control wells, after sealing
In 37 DEG C of constant temperature diffusion reaction 8-10h, each reacting hole precipitation loop diameter (mm) is measured.
The effect of thrombin activity is inhibited to see attached drawing 1.
As shown in Figure 1, the anti-red blood silk composition of various concentration has apparent inhibition thrombin activity, especially 5% concentration
Inhibition is the most notable.The Chinese medical extract that inventor is prepared with embodiment 2,3 repeats to test according to the method described above, experiment knot
Fruit sees attached drawing 2,3 respectively, finds the Chinese medical extract experimental result prepared with embodiment 1, this will not be repeated here.
Following example 5-10 is the external-use skin care product containing anti-red blood silk Chinese medical extract
Embodiment 5 (containsThe face cream of anti-red blood silk Chinese medical extract)
The present inventionContainThe test sample raw material components and preparation process of the face cream of anti-red blood silk Chinese medical extract are as follows：
By the formula of table 1, in a suitable container, the ingredient of A phases is heated to 75 DEG C~85 DEG C under stiring.
In another container, the ingredient of B phases is heated to 75 DEG C~85 DEG C under stiring.Then, B is added in A phases under stiring,
Homogeneous 5~15 minutes, homogeneous speed are 2000~3000r/min, hereafter under stiring, mixture are cooled to 70 DEG C, C is added
Phase is cooled to 40 DEG C of addition D phases, is further continued for stirring and is cooled to 38 DEG C of dischargings.
Face cream and control sample (unit of the table 1 containing anti-red blood silk Chinese medical extract：Weight percent %)
Effete test embodiment 2
The clinical evaluation of the anti-red blood silk Chinese medical extract face cream of embodiment 5
1) test purpose：Whether 5 anti-red blood silk Chinese medical extract face cream of testing example has the active (phase of anti-red blood silk
For not adding the blank control example 0 of Chinese medical extract, placebo is called in the following text).
2) test method：Double-blind (addition Chinese medical extract and placebo).
3) number is tested：20, clinical manifestation, which is face, apparent secondary red blood silk.
4) test period：28 days.
5) applying amount：During entire test, smearing position is face, and different subject's left and right faces are grouped at random, per half of
Face is fixed respectively to smear embodiment 5 or placebo, and sooner or later primary daily, average applying amount is 2.8 ㎎/㎡.
6) standard
It cures：Clinical symptoms disappear；
Effectively：Clinical symptom relief, red blood silk are thin out；
In vain：Clinical symptoms do not improve.
7) result
Quick, 7 days efficient up to 80.6%, and has certain cure rate, and 28 days cure rates are 69.93%.It is right
Secondary red blood silk therapeutic effect is notable.There is no an example reaction phenomena such as allergy, skin is uncomfortable occur.
The face cream that inventor is prepared with embodiment 6,7,8,9 and 10 repeats to test according to the method described above, and experimental result is same
The experimental result of 5 face cream of embodiment, this will not be repeated here.
In conclusion the present invention offer extracted obtained Chinese medical extract of Chinese medicine composition has promotes micro- follow well
The effect of ring, factor that diminishes inflammation, anti-red blood silk is apparent, and preparation method is easy, the skin care formulation being prepared using it, institute
Product Green safety is obtained, obvious effect easily absorbs.
The above described is only a preferred embodiment of the present invention, be not intended to limit the present invention in any form, therefore
It is every without departing from technical solution of the present invention content, simply repaiied to any made by above example according to the technical essence of the invention
Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (7)
1. a kind of Chinese medical extract of anti-red blood silk, it is characterised in that：The bulk pharmaceutical chemicals matched by following weight parts are made：
40~60 parts of Rabdosia rubescens, 10~30 parts of oldenlandia diffusa, 10~30 parts of Radix Astragali；
The Chinese medical extract is prepared according to following processing step：
1) Rabdosia rubescens, oldenlandia diffusa, Radix Astragali are crushed to 60~100 mesh respectively, it is then mixed according to the weight
It closes uniformly, obtains Chinese medicine composition；
2) it is that 30~70% ethyl alcohol extract to obtain extracting solution, the Chinese medicine percent by volume to be added in above-mentioned Chinese medicine composition
The bulking value ratio g/mL of composition and ethyl alcohol is 1：10~1：20；
3) extracting solution for preparing step 2) stands 1~4 hour, and after the filtering of 100~200 mesh, vacuum filtration is extremely clarified, decompression rotation
Turn to be evaporated to, without ethyl alcohol, using 90~100 DEG C of sterilizings under normal pressure, Chinese medical extract to be finally prepared.
2. a kind of application of Chinese medical extract of anti-red blood silk in skin care item, it is characterised in that：The skin care item include：Right
It is required that 1 Chinese medical extract being prepared；And 90~99.9% skin care field customary adjuvant.
3. application of the Chinese medical extract of anti-red blood silk according to claim 2 in skin care item, it is characterised in that：By weight
Percentages are measured, the Chinese medical extract accounts for the 0.1%~10% of skin care item total amount.
4. application of the Chinese medical extract of anti-red blood silk according to claim 2 in skin care item, it is characterised in that：By weight
Percentages are measured, the Chinese medical extract accounts for the 0.5%~5% of skin care item total amount.
5. application of the Chinese medical extract of anti-red blood silk according to claim 2 in skin care item, it is characterised in that：It is described
Customary adjuvant includes surfactant, thickener, conditioner, moisturizer, preservative, chelating agent, essence, deionized water.
6. application of the Chinese medical extract of anti-red blood silk according to claim 2 in skin care item, it is characterised in that：It is described
Skin care item can be made into toner, smoothing toner, firming lotion, nutrition toner, nourishing cream, massage cream, essence, eye cream, cleansing cream, clean
Skin foam, clarifying lotion, facial mask, muffin, body dew, body frost, body oil and body lotion.
7. application of the Chinese medical extract of anti-red blood silk according to claim 6 in skin care item, it is characterised in that：It is described
Essence is selected from eye essence, body essence.
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| FR2997299B1 (en) * | 2012-10-30 | 2014-12-26 | Sederma Sa | ASSOCIATION OF PLANT EXTRACTS, COSMETIC ACTIVE INGREDIENT AND COMPOSITION CONTAINING THE SAME, AND COSMETIC TOPICAL USE |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| FR2997299B1 (en) * | 2012-10-30 | 2014-12-26 | Sederma Sa | ASSOCIATION OF PLANT EXTRACTS, COSMETIC ACTIVE INGREDIENT AND COMPOSITION CONTAINING THE SAME, AND COSMETIC TOPICAL USE |
| CN103908419A (en) * | 2012-12-31 | 2014-07-09 | 北京工商大学 | Aloe-containing traditional Chinese medicine composition with efficacy of promoting skin microcirculation, preparation and preparation method |
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| CN105596249A (en) | 2016-05-25 |
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Effective date of registration: 20221028 Address after: 515834 Liannan Industrial Zone, Chenghai District, Shantou City, Guangdong Province Patentee after: Guangdong Mingchen Daily Chemical Co.,Ltd. Address before: 515834 Liannan Industrial Zone, Lianxia Town, Chenghai District, Shantou City, Guangdong Province Patentee before: MINGCHEN HEALTH Co.,Ltd. |