CN105582468A - 治疗面肌痉挛的中药组合物 - Google Patents
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Abstract
本发明涉及中药配方领域,具体地说是一种治疗面肌痉挛的中药组合物,其特征在于由如下重量百分比的原料药制成,郁金6~9%、猫爪草4~7%、藁本6~9%、乌蔹莓4~7%、金樱子6~9%、千年键3~5%、芡实10~13%、白僵蚕0.1~0.2%、苦楝皮10~13%、楮实子3~6%、九龙盘3~5%、见血飞2~5%、锡生藤3~6%、落马衣3~6%、升麻4~6%、急性子2~5%、灯心草2~4%、楤木2~4%,将上述原料药用水浸泡,煎熬后去渣得滤液。
Description
技术领域
本发明涉及一种中成药制剂,具体地说是一种治疗面肌痉挛的中药组合物。
背景技术
众所周知,面肌痉挛是一种以一侧面部肌肉阵发性不自主抽动为特点,无神经系统其他阳性体征的周围神经病。临床上多表现为一侧面部阵发性、不规则性、不自主的抽动,常始于眼睑附近,渐往下向面部其它肌肉发展,严重者整个面部的肌肉均剧烈抽动,属临床常见病及难治病,故应早期诊断,及时治疗。现代医学认为,引起面肌痉挛的原因主要与血管被压迫有关,形成血管襻或异位压迫面神经,导致面神经的异位兴奋或伪突触传导引起的面部肌肉抽动。目前,西医学尚无特殊、有效的治疗方法,多是用安定、利眠宁或苯妥英钠、卡马西平以及大剂量的维生素治疗,对重症患者进行酒精或者药物封闭、面神经减压术等。但往往西药治疗疗效差,副作用大,治疗效果不满意。
发明内容
本发明目的就是为了克服上述现有的技术不足,提供一种治疗过敏性鼻炎的药物,成本低,疗效高,无毒副作用。
本发明解决上述技术问题采用的技术方案是:一种治疗面肌痉挛的中药组合物,其特征在于由如下重量百分比的原料药制成,郁金6~9%、猫爪草4~7%、藁本6~9%、乌蔹莓4~7%、金樱子6~9%、千年键3~5%、芡实10~13%、白僵蚕0.1~0.2%、苦楝皮10~13%、楮实子3~6%、九龙盘3~5%、见血飞2~5%、锡生藤3~6%、落马衣3~6%、升麻4~6%、急性子2~5%、灯心草2~4%、楤木2~4%,将上述原料药用水浸泡,煎熬后去渣得滤液。
本发明的有益效果是,成本低,疗效高,无毒副作用。
具体实施方式
下面结合实施例对本发明作进一步的描述:
实施例1:采用郁金、猫爪草、藁本、乌蔹莓、金樱子、千年键、芡实、白僵蚕、苦楝皮、楮实子、九龙盘、见血飞、锡生藤、落马衣、升麻、急性子、灯心草、楤木为原料药制备而成。其组分(重量%)每副为郁金8.3、猫爪草6.2、藁本8.1、乌蔹莓6.1、金樱子8.1、千年键4.6、芡实10.8、白僵蚕0.2、苦楝皮11.3、楮实子4.4、九龙盘4.6、见血飞3.9、锡生藤4.4、落马衣4.9、升麻4.3、急性子3.9、灯心草3.1、楤木2.8。取上述18味中草药原料,总重量为200克,加水1100~1300ml,浸泡2~3小时,然后用武火煮沸,文火煎熬60~70分钟,去渣得滤液200ml左右,药渣再加水300~400ml,煎熬30分钟左右,去渣得滤液100ml左右,共得300ml左右药汁,装入无菌玻璃瓶内,密封瓶盖备用。每日1剂分2次口服,每次空腹服150ml左右。
本发明郁金活血止痛,行气解郁,清心凉血,利胆退黄;猫爪草化痰散结,解毒消肿;藁本祛风,散寒,除湿,止痛;乌蔹莓清热利湿,解毒消肿;金樱子具有固精缩尿,固崩止带,涩肠止泻之功效;千年键祛风湿,健筋骨。用于风寒湿痹,腰膝冷痛,下肢拘挛麻木;芡实具有益肾固精,补脾止泻,除湿止带之功效;白僵蚕治中风失音,惊痫,头风,喉风;苦楝皮治游风热毒,风疹疮疥癞;楮实子补肾清肝、明目、利尿。用于腰膝酸软、虚劳骨蒸、砂晕目昏、目生翳膜、水肿胀满;九龙盘中,散寒,祛风,活血。治脘腹冷痛,风湿筋骨疼痛;见血飞祛风散寒,活血舒筋,镇痛,治风寒咳嗽,风湿麻木,跌打损伤;锡生藤肿止痛,止血,生肌。用于外伤肿痛,创伤出血;落马衣治风湿骨痛、感冒发热、呕吐腹痛、胃气痛、皮肤湿疹;升麻发表透疹,清热解毒,升阳举陷;急性子破血消积,软坚散结。用于经闭,积块,噎膈,外疡坚肿;灯心草用于心烦失眠,尿少涩痛,口舌生疮;楤木祛风除湿利水和中活血解毒。
本发明各原料还可按下表所列比例(重量百分比)混合的实施例来实现,其煎熬程序、口服方法与实施例1相同,其含量如下表所示。
实施例 | 郁金 | 猫爪草 | 藁本 | 乌蔹莓 | 金樱子 | 千年键 | 芡实 | 白僵蚕 | 苦楝皮 | 楮实子 | 九龙盘 | 见血飞 | 锡生藤 | 落马衣 | 升麻 | 急性子 | 灯心草 | 楤木 |
二 | 6 | 7 | 9 | 7 | 7.8 | 5 | 10 | 0.2 | 10 | 6 | 3 | 5 | 3 | 6 | 4 | 5 | 2 | 4 |
三 | 9 | 6.9 | 9 | 4 | 9 | 3 | 13 | 0.1 | 13 | 3 | 5 | 2 | 6 | 3 | 6 | 2 | 4 | 2 |
四 | 9 | 4 | 6 | 7 | 6 | 5 | 12 | 0.2 | 11 | 5 | 4 | 5 | 5 | 5 | 6 | 4 | 2.8 | 3 |
五 | 8 | 6 | 8 | 6 | 8 | 4 | 13 | 0.2 | 12 | 4 | 4 | 3 | 5.8 | 4 | 5 | 4 | 3 | 2 |
临床资料
下面通过临床资料来说明本发明中药的药效:
1、一般资料
60例患者中,年龄28-49岁,病程多在1个月到1年。
2、诊断标准
参照《现代中医临床诊断学》中的诊断依据进行临床诊断:
2.1早期多为眼轮匝肌间歇性抽搐,渐至同侧其他面肌;
2.2抽搐程度不等,可因劳累、精神紧张及谈话等因素加剧,入睡则抽搐停止;
2.3神经系统检查无阳性体征,头颅CT等检查无病变。
排除功能性眼睑痉挛、Meige综合征、习惯性抽动症、抗精神药物引起面肌运动障碍。
3、治疗方法
服用实施例一药剂,每日1剂分2次口服,每次空腹服150ml左右,服用两个月。
4、治疗结果
4.1治疗评定标准,根据国家中医药管理局制定的《中医病证诊断疗效标准》判定:
治愈:面肌抽搐症状消失,随访6~12个月无复发;
显效:面肌抽搐发作次数和频率明显降低,症状显著减轻,发作次数降低2/3以上;
好转:面肌抽搐症状减轻,每天发作次数约为治疗前2/3者;
无效:主要症状无变化者。
4.2结果:60例患者中,痊愈26例,显效19例,好转13例,无效2例,总有效率为97%。
典型病例
常某某,女,46岁。一年前出现右眼皮跳动,未予重视。此后逐渐加重并扩张至左面部口角肌肉抽搐,不能自控。情绪紧张、疲劳、睡眠不好时诱发加重。曾于针灸科行针灸理疗,治疗期间症状可见缓解,治疗停止则症状加重。就诊时左面部肌肉抽搐,略感腰部酸胀,面色红润,纳可,二便调,夜寐安。舌红苔白,脉弦。服用本发明中药一个月后,症状缓解,继续服用一个月,右侧面部肌肉抽搐基本消失,随访1年,痊愈。
2、马某,男,31岁,左侧面部肌肉不自主抽动3个多月。就诊时患者左侧面部肌肉跳动,偶有白痰,纳可,寐安,二便调,舌淡红苔黄腻,脉濡弱。服用本发明中药一个月后,各种症状较前好转。继续服用一个月,左侧面部肌肉抽搐基本消失,随访6个月,痊愈。
Claims (1)
1.一种治疗面肌痉挛的中药组合物,其特征在于:由如下重量百分比的原料药制成,郁金6~9%、猫爪草4~7%、藁本6~9%、乌蔹莓4~7%、金樱子6~9%、千年键3~5%、芡实10~13%、白僵蚕0.1~0.2%、苦楝皮10~13%、楮实子3~6%、九龙盘3~5%、见血飞2~5%、锡生藤3~6%、落马衣3~6%、升麻4~6%、急性子2~5%、灯心草2~4%、楤木2~4%,将上述原料药用水浸泡,煎熬后去渣得滤液。
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