CN105581041A - High calcium emulsion for promoting pet joint repair and preparation method thereof - Google Patents
High calcium emulsion for promoting pet joint repair and preparation method thereof Download PDFInfo
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- CN105581041A CN105581041A CN201510913346.5A CN201510913346A CN105581041A CN 105581041 A CN105581041 A CN 105581041A CN 201510913346 A CN201510913346 A CN 201510913346A CN 105581041 A CN105581041 A CN 105581041A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
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Abstract
The present invention discloses a high calcium emulsion for promoting pet joint repair and a preparation method thereof. The high calcium emulsion consists of the following components in parts by weight: 8-10 parts of D-glucosamine hydrochloride, 2-5 parts of calcium phosphate, 3-5 parts of chondroitin sulfate, 0.01-0.1 part of vitamin A, 0.1-0.2 part of vitamin D3, 50-55 parts of glucose syrup, 35-40 parts of purified water, 0.05-0.1 part of sodium carboxymethylcellulose, 0.05-0.1 part of xanthan gum, 0.05-0.1 part of guar gum, 0.05-0.1 part of single and double glycerol fatty acid ester, 0.05-0.1 part of sodium tripolyphosphate, 0.01-0.05 part of sodium citrate, 0.01-0.05 part of sodium hexametaphosphate, 0.01-0.05 part of sodium pyrophosphate, 0.01-0.05 part of carrageenan, 0.1-0.2 part of agar, 0.01-0.05 part of sucrose fatty acid ester, 0.01-0.05 part of maltodextrin, 0.05-0.1 part of potassium sorbate and 0.2-0.4 part of beef flavor. The high calcium emulsion is prepared according to the medical theoretical formulation and a certain weight ratio, and by using a scientific production technology. The high calcium emulsion can efficiently supplement calcium for pets, at the same time can also promote the deposition of calcium in the bones, protects the health of cartilage and bone matrix, and more effectively repair pet joints and increase bone density.
Description
Technical field
The present invention relates to animal medicine technical field, refer more particularly to a kind of high calcium emulsion that promotes pet joint reparation and preparation method thereof.
Background technology
Pet, is mankind close friend, companion, and the health of pet also affects owner's the heart constantly. When the calcium insufficiency of intakes of the pets such as dog cat, tend to occur following symptom:
1, after the cub of large-scale pet ablactation, build fast growth, especially eat self-control food more need replenish the calcium in time.
2, eat for a long time animal's liver and carnivorous, the calcium content of this group food is low and vitamin A content is high, and the vitamin A of high concentration can suppress the absorption of body to calcium.
3, be the important period that interverbebral disc forms when pet 2--3 month childhood, if calcium deficiency can cause interverbebral disc depauperation. Especially Shih Tzu, pug, Beijing dog etc.
4, childhood pet dental transitional period. Now permanent tooth starts growth, if calcium deficiency can cause permanent tooth poor growth, uneven, adamantine layer is thin, insecure, easily suffers from the mouth diseases such as gingivitis, halitosis after growing up.
5, grow up kind of a male dog, tom, period of pregnancy bitch, female cat. The seminal fluid of the male pet of kind now, the embryo of conceived dog and lactation milk loss can take away a large amount of calcium, can make calcium storehouse calcium deficiency cause osteoporosis if supplement deficiency.
6, the female pet of postpartum breastfeeding phase. Now calcium deficiency majority is acute calcium deficiency, and tic of limbs, whole body are stiff, hyperthermia, even stupor, death.
7, old pet. With advancing age, the degeneration gradually of each portion function, endocrinopathy, calcium intake attenuating can cause osteoporosis.
Summary of the invention
The object of this invention is to provide a kind of high calcium emulsion that promotes pet joint reparation and preparation method thereof.
To achieve these goals, the invention provides a kind of high calcium emulsion that promotes that pet joint is repaired, formed by the component of following weight parts: D-Glucosamine Hydrochloride 8-10 part, calcium phosphate 2-5 part, chondroitin sulfate 3-5 part, vitamin A 0.01-0.1 part, vitamin D30.1-0.2 part, glucose syrup 50-55 part, purified water 35-40 part, sodium carboxymethylcellulose 0.05-0.1 part, xanthans 0.05-0.1 part, guar gum 0.05-0.1 part, list, diglycerine fatty acid ester 0.05-0.1 part, sodium phosphate trimer 0.05-0.1 part, natrium citricum 0.01-0.05 part, calgon 0.01-0.05 part, sodium pyrophosphate 0.01-0.05 part, carragheen 0.01-0.05 part, agar 0.1-0.2 part, sucrose fatty ester 0.01-0.05 part, maltodextrin 0.01-0.05 part, potassium sorbate 0.05-0.1 part, essence 0.2-0.4 part.
As the preferred technical solution of the present invention, described raw material comprises the component of following weight portion: by sodium carboxymethylcellulose 0.05-0.1 part, xanthans 0.05-0.1 part, guar gum 0.05-0.1 part, single, diglycerine fatty acid ester 0.05-0.1 part, sodium phosphate trimer 0.05-0.1 part, natrium citricum 0.01-0.05 part, calgon 0.01-0.05 part, sodium pyrophosphate 0.01-0.05 part, carragheen 0.01-0.05 part, agar 0.1-0.2 part, sucrose fatty ester 0.01-0.05 part, maltodextrin 0.01-0.05 part is through weighing, after mixing, in the purified water purified water 35-40 part joining, then carrying out 50 DEG C of heating water baths makes it fully be swelled into stable emulsifing thickener, efficient stable, guaranteed quality.
Further, the high calcium emulsion that above-mentioned promotion pet joint is repaired, add by D-Glucosamine Hydrochloride 8-10 part, calcium phosphate 2-5 part, the premix of chondroitin sulfate 3-5 part through weighing, pulverizing, cross 30 mesh sieves, be mixed into, thereby can repair efficiently, fast pet joint, the simultaneously efficient calcium that supplements fast, allows the object of pet health, vigor to reach.
Further, the high calcium emulsion that above-mentioned promotion pet joint is repaired, is characterized in that, described essence is beef flavor, good palatability, and pet is liked to eat, just can better absorb.
A preparation method who promotes the high calcium emulsion of pet joint reparation, comprises the steps:
1) lead material proportioning according to above-mentioned weight ratio;
2) in purified water, add sodium carboxymethylcellulose 0.05-0.1 part, xanthans 0.05-0.1 part, guar gum 0.05-0.1 part, list, diglycerine fatty acid ester 0.05-0.1 part, sodium phosphate trimer 0.05-0.1 part, natrium citricum 0.01-0.05 part, calgon 0.01-0.05 part, sodium pyrophosphate 0.01-0.05 part, carragheen 0.01-0.05 part, agar 0.1-0.2 part, sucrose fatty ester 0.01-0.05 part, maltodextrin 0.01-0.05 part, then carry out 50 DEG C of heating water baths, make it fully swelling, obtain mixture 1.;
3) add successively D-Glucosamine Hydrochloride 8-10 part, calcium phosphate 2-5 part, chondroitin sulfate 3-5 part, vitamin A 0.01-0.1 part, vitamin D to mixture in 1. again30.1-0.2 part, glucose syrup 50-55 part, and carry out 40 with vacuum stirring mulser and turn and stir, mixture obtained 2.;
4) 2. the most backward mixture adds potassium sorbate 0.05-0.1 part, beef flavor 0.2-0.4 part, then vacuumizes the rear emulsifying of stirring and gets final product to obtain emulsion;
5) use Intelligent liquid filling machine filling, every bottle of 200ml;
6) carry out successively inner packing, external packing; Censorship; Warehouse-in.
The present invention can also promote its deposition in bone in giving pet high efficiency calcium-enriching; protect the health of cartilage and bone matrix; more can effectively repair pet joint health, increase bone density; according to theory of medicine formula; according to constant weight proportioning, use the production technology of science to be prepared from.
Compared with prior art, technical scheme provided by the invention has the following advantages:
1. this product, taking calcium phosphate as calcium constituent, have high dispersive, high-effect, high absorption, and optimal calcium phosphorus ration is easier to pet health;
2. high calcium emulsion provided by the invention can be repaired joint, bone density more in replenishing the calcium, and makes pet bone more healthy.
3. the beef flavor that this product adds, shows through great many of experiments, inferior product palatability is high, and resistance to mouthful of property is lasting, no matter is to mix in dog grain, or directly feeding is all very convenient.
Detailed description of the invention
Below in conjunction with detailed description of the invention, describe technical scheme of the present invention in detail:
Embodiment 1
Promote the high calcium emulsion that pet joint is repaired, formed by the component of following weight parts: 8 parts of D-Glucosamine Hydrochlorides, 2 parts, calcium phosphate, 3 parts of chondroitin sulfates, 0.01 part of vitamin A, vitamin D30.1 part, 50 parts of glucose syrups, 35 parts of purified water, 0.05 part of sodium carboxymethylcellulose, 0.05 part of xanthans, 0.05 part of guar gum, single, 0.05 part of diglycerine fatty acid ester, 0.05 part of sodium phosphate trimer, 0.01 part of natrium citricum, 0.01 part of calgon, 0.01 part of sodium pyrophosphate, 0.01 part of carragheen, 0.1 part, agar, 0.01 part of sucrose fatty ester, 0.01 part of maltodextrin, 0.05 part of potassium sorbate, 0.2 part of beef flavor.
The preparation method of the high calcium emulsion that described promotion pet joint is repaired is as follows:
First lead material proportioning according to above-mentioned weight ratio; In purified water, add 0.05 part of sodium carboxymethylcellulose, 0.05 part of xanthans, 0.05 part of guar gum, single, 0.05 part of diglycerine fatty acid ester, 0.05 part of sodium phosphate trimer, 0.01 part of natrium citricum, 0.01 part of calgon, 0.01 part of sodium pyrophosphate, 0.01 part of carragheen, 0.1 part, agar, 0.01 part of sucrose fatty ester, 0.01 part of maltodextrin, then carry out 50 DEG C of heating water baths, make it fully swelling, obtain mixture 1.; 1. add successively 8 parts of D-Glucosamine Hydrochlorides, 2 parts, calcium phosphate, 3 parts of chondroitin sulfates, 0.01 part of vitamin A, vitamin D to mixture in again350 parts of 0.1 parts, glucose syrup, and carry out 40 with vacuum stirring mulser and turn and stir, mixture obtained 2.;
2. the most backward mixture adds 0.05 part of potassium sorbate, 0.2 part of beef flavor, then vacuumizes the rear emulsifying of stirring and gets final product to obtain emulsion; Finally use Intelligent liquid filling machine filling, every bottle of 200ml; Carry out inner packing, external packing; Censorship, warehouse-in.
Embodiment 2
Promote the high calcium emulsion that pet joint is repaired, formed by the component of following weight parts: 9 parts of D-Glucosamine Hydrochlorides, 3 parts, calcium phosphate, 4 parts of chondroitin sulfates, 0.05 part of vitamin A, vitamin D30.15 part, 53 parts of glucose syrups, 37 parts of purified water, 0.75 part of sodium carboxymethylcellulose, 0.75 part of xanthans, 0.75 part of guar gum, single, 0.75 part of diglycerine fatty acid ester, 0.75 part of sodium phosphate trimer, 0.03 part of natrium citricum, 0.03 part of calgon, 0.03 part of sodium pyrophosphate, 0.03 part of carragheen, 0.15 part, agar, 0.03 part of sucrose fatty ester, 0.03 part of maltodextrin, 0.03 part of potassium sorbate, 0.3 part of beef flavor.
Preparation technology is with embodiment 1.
Embodiment 3
Promote the high calcium emulsion that pet joint is repaired, formed by the component of following weight parts: 10 parts of D-Glucosamine Hydrochlorides, 5 parts, calcium phosphate, 5 parts of chondroitin sulfates, 0.1 part of vitamin A, vitamin D30.2 part, 55 parts of glucose syrups, 40 parts of purified water, 0.1 part of sodium carboxymethylcellulose, 0.1 part of xanthans, 0.1 part of guar gum, single, 0.1 part of diglycerine fatty acid ester, 0.1 part of sodium phosphate trimer, 0.05 part of natrium citricum, 0.05 part of calgon, 0.05 part of sodium pyrophosphate, 0.05 part of carragheen, 0.2 part, agar, 0.05 part of sucrose fatty ester, 0.05 part of maltodextrin, 0.1 part of potassium sorbate, 0.4 part of beef flavor.
Preparation technology is with embodiment 1.
In the time of concrete use: directly feeding pet or make an addition in grain, drinking-water.
Provide advantage of the present invention place use case of the present invention below and be explained in order better to illustrate.
Case 1
Suffer from dog: Japanese autumn fields dog, male, 3 first quarter moons
Symptom: rear myasthenia of limbs, the half sole bending palm of lying prone, slightly turns row
Analyze the cause of disease: after the cub ablactation of large-scale pet, dog dog calcium deficiency
Therapeutic scheme: the high calcium emulsion of promotion pet joint provided by the invention reparation is extruded in dog grain and mixes together food, every day 2 times, each 3 milliliters, be used in conjunction 7 days, after be kept to once a day, each 3 milliliters. Dog dog is liked to eat very much. After one week, strength is felt out, no longer turns row. Be used in conjunction 3 months, hind leg is strong, the palm of no longer lying prone. Continue according to 2 milliliters of health care amount every days, to 7 months.
Case 2
Suffer from dog: Shih Tzu, female, 3 months
Symptom: interverbebral disc depauperation, rear myasthenia of limbs, does not like activity
Analyze the cause of disease: dog dog calcium deficiency, interverbebral disc depauperation
Therapeutic scheme: the direct feeding of high calcium emulsion that promotion pet joint provided by the invention is repaired, every day 2 times, each 4 milliliters, be used in conjunction 3 days, after be kept to once a day, each 3 milliliters. Dog dog is liked to eat very much. After 7 days, Shih Tzu can run, chase. Be used in conjunction after first quarter moon, hind leg is strong, the palm of no longer lying prone, and it is normal that action recovers.
Case 3
Suffer from dog: Persian cat, female, 1 years old 8 months
Symptom: myasthenia of limbs after postpartum, to walk unstable, lassitude, does not like motion
Analyze the cause of disease: osteoporosis, cat calcium deficiency
Therapeutic scheme: the high calcium emulsion of promotion pet joint provided by the invention reparation and cat grain are mixed to food, every day 1 time, each 6 milliliters, be used in conjunction 3 weeks, after be kept to once a day, each 3 milliliters. After 5 days, can walk steadily. Be used in conjunction after first quarter moon, hind leg is strong, and it is normal that action recovers.
Case 4
Suffer from dog: Bali cat, male, 8 years old
Symptom: geriatric cat, arthroncus, distortion, cannot walk
Analyze the cause of disease: calcium deficiency, bone density weaken the dysarthrasis causing
Therapeutic scheme: the high calcium emulsion of promotion pet joint provided by the invention reparation is mixed to food together with cat grain, every day 1 time, each 7 milliliters, be used in conjunction two weeks, after be kept to once a day, each 5 milliliters. Be used in conjunction after two weeks, can walk, after one month, swelling slowly disappears. Bone density strengthens, and gets well.
Claims (4)
1. promote the high calcium emulsion that pet joint is repaired, it is characterized in that, each component according to quality proportioning is: D-Glucosamine Hydrochloride 8-10 part, calcium phosphate 2-5 part, chondroitin sulfate 3-5 part, vitamin A 0.01-0.1 part, vitamin D30.1-0.2 part, glucose syrup 50-55 part, purified water 35-40 part, sodium carboxymethylcellulose 0.05-0.1 part, xanthans 0.05-0.1 part, guar gum 0.05-0.1 part, list, diglycerine fatty acid ester 0.05-0.1 part, sodium phosphate trimer 0.05-0.1 part, natrium citricum 0.01-0.05 part, calgon 0.01-0.05 part, sodium pyrophosphate 0.01-0.05 part, carragheen 0.01-0.05 part, agar 0.1-0.2 part, sucrose fatty ester 0.01-0.05 part, maltodextrin 0.01-0.05 part, potassium sorbate 0.05-0.1 part, essence 0.2-0.4 part.
2. a kind of high calcium emulsion that promotes that pet joint is repaired according to claim 1, is characterized in that, is weighed, pulverizes, crosses 30 mesh sieves, is mixed into premix by D-Glucosamine Hydrochloride 8-10 part, calcium phosphate 2-5 part, chondroitin sulfate 3-5 part process.
3. a kind of high calcium emulsion that promotes that pet joint is repaired according to claim 1, is characterized in that, described essence is beef flavor.
4. a preparation method who promotes the high calcium emulsion of pet joint reparation, is characterized in that, comprises the steps:
1) expect, take each component according to the weight proportion neck described in claims 1;
2) in the purified water taking to step 1), add sodium carboxymethylcellulose 0.05-0.1 part, xanthans 0.05-0.1 part, guar gum 0.05-0.1 part, list, diglycerine fatty acid ester 0.05-0.1 part, sodium phosphate trimer 0.05-0.1 part, natrium citricum 0.01-0.05 part, calgon 0.01-0.05 part, sodium pyrophosphate 0.01-0.05 part, carragheen 0.01-0.05 part, agar 0.1-0.2 part, sucrose fatty ester 0.01-0.05 part, maltodextrin 0.01-0.05 part, then carry out 50 DEG C of heating water baths, make it fully swelling, obtain mixture 1.;
3) add successively D-Glucosamine Hydrochloride 8-10 part, calcium phosphate 2-5 part, chondroitin sulfate 3-5 part, vitamin A 0.01-0.1 part, vitamin D to mixture in 1. again30.1-0.2 part, glucose syrup 50-55 part, and carry out 40 with vacuum stirring mulser and turn and stir, mixture obtained 2.;
4) 2. the most backward mixture adds potassium sorbate 0.05-0.1 part, beef flavor 0.2-0.4 part, then vacuumizes the rear emulsifying of stirring and gets final product to obtain emulsion;
5) use Intelligent liquid filling machine filling, every bottle of 200ml;
6) carry out successively inner packing, external packing; Censorship, warehouse-in.
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| CN201510913346.5A CN105581041A (en) | 2015-12-12 | 2015-12-12 | High calcium emulsion for promoting pet joint repair and preparation method thereof |
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| CN201510913346.5A CN105581041A (en) | 2015-12-12 | 2015-12-12 | High calcium emulsion for promoting pet joint repair and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106581061A (en) * | 2016-12-18 | 2017-04-26 | 杨箭 | High-calcium emulsion for pet joint repair and preparation method thereof |
| CN106615875A (en) * | 2016-12-16 | 2017-05-10 | 杨箭 | High-calcium emulsion for pets and preparation method of high-calcium emulsion |
| CN107952066A (en) * | 2017-11-20 | 2018-04-24 | 江苏雅博动物健康科技有限责任公司 | A kind of pet liquid calcium and preparation method thereof |
| CN108853020A (en) * | 2018-09-04 | 2018-11-23 | 山东亚华生物科技有限公司 | A kind of pet emulsion and its preparation process of replenishing the calcium |
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| CN101322551A (en) * | 2007-08-31 | 2008-12-17 | 辽源雷霓森药业有限公司 | Combination for increasing bone density and repairing articular cartilage |
| CN103191414A (en) * | 2013-03-29 | 2013-07-10 | 武汉中博绿亚生物科技有限公司 | Fast-absorbed liquid calcium for pet and preparation method thereof |
| CN103301149A (en) * | 2012-03-12 | 2013-09-18 | 深圳市麦金利实业有限公司 | Medicinal preparation capable of increasing bone mineral density and improving osteoporosis |
| CN104188999A (en) * | 2014-08-13 | 2014-12-10 | 哈药集团制药六厂 | Composition capable of increasing bone density and improving functions of skeletons and joints and preparation method thereof |
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2015
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101322551A (en) * | 2007-08-31 | 2008-12-17 | 辽源雷霓森药业有限公司 | Combination for increasing bone density and repairing articular cartilage |
| CN103301149A (en) * | 2012-03-12 | 2013-09-18 | 深圳市麦金利实业有限公司 | Medicinal preparation capable of increasing bone mineral density and improving osteoporosis |
| CN103191414A (en) * | 2013-03-29 | 2013-07-10 | 武汉中博绿亚生物科技有限公司 | Fast-absorbed liquid calcium for pet and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106615875A (en) * | 2016-12-16 | 2017-05-10 | 杨箭 | High-calcium emulsion for pets and preparation method of high-calcium emulsion |
| CN106581061A (en) * | 2016-12-18 | 2017-04-26 | 杨箭 | High-calcium emulsion for pet joint repair and preparation method thereof |
| CN107952066A (en) * | 2017-11-20 | 2018-04-24 | 江苏雅博动物健康科技有限责任公司 | A kind of pet liquid calcium and preparation method thereof |
| CN108853020A (en) * | 2018-09-04 | 2018-11-23 | 山东亚华生物科技有限公司 | A kind of pet emulsion and its preparation process of replenishing the calcium |
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Address after: No. 18, Jingjiang City, Jiangsu, Taizhou, Jiangsu Applicant after: Albert Jiangsu animal health technology limited liability company Address before: 214500, 61 Jiangshan Road, Taizhou, Jiangsu, Jingjiang Applicant before: ABRAM (JIANGSU) ANIMAL HEALTH CO., LTD. |
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