CN105579052A - 药物组合物 - Google Patents

药物组合物 Download PDF

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Publication number
CN105579052A
CN105579052A CN201480053586.6A CN201480053586A CN105579052A CN 105579052 A CN105579052 A CN 105579052A CN 201480053586 A CN201480053586 A CN 201480053586A CN 105579052 A CN105579052 A CN 105579052A
Authority
CN
China
Prior art keywords
insulin
derivatives
isoelectric point
pharmaceutical composition
metabolites
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201480053586.6A
Other languages
English (en)
Chinese (zh)
Inventor
马哈拉杰·K·萨赫比
吉滕德拉·喀什纳什·亚姆布格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wockhardt Ltd
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Ltd filed Critical Wockhardt Ltd
Publication of CN105579052A publication Critical patent/CN105579052A/zh
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
CN201480053586.6A 2013-09-30 2014-09-29 药物组合物 Withdrawn CN105579052A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN3124/MUM/2013 2013-09-30
IN3124MU2013 IN2013MU03124A (enExample) 2013-09-30 2014-09-29
PCT/IB2014/064922 WO2015044922A1 (en) 2013-09-30 2014-09-29 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
CN105579052A true CN105579052A (zh) 2016-05-11

Family

ID=51903957

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480053586.6A Withdrawn CN105579052A (zh) 2013-09-30 2014-09-29 药物组合物

Country Status (10)

Country Link
US (1) US20160271226A1 (enExample)
EP (1) EP3052114A1 (enExample)
JP (1) JP2016531847A (enExample)
CN (1) CN105579052A (enExample)
AU (1) AU2014326181A1 (enExample)
BR (1) BR112016006963A2 (enExample)
IN (1) IN2013MU03124A (enExample)
RU (1) RU2016107610A (enExample)
SG (1) SG11201601477VA (enExample)
WO (1) WO2015044922A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729639A (zh) * 2017-01-10 2017-05-31 鲁南制药集团股份有限公司 一种甘精胰岛素注射液及其制备方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017145104A1 (en) 2016-02-25 2017-08-31 Wockhardt Limited Pharmaceutical composition of insulin glargine and amino acids
AU2018308692A1 (en) * 2017-07-27 2020-03-05 Adocia Compositions in the form of an injectable aqueous solution comprising at least human insulin A21G and a prandial action glucagon suppressor
AU2020324961A1 (en) * 2019-08-02 2022-03-24 Case Western Reserve University Premixed ultra-stable single-chain insulin analogue formulations
EP3915571A1 (en) * 2020-05-29 2021-12-01 Adocia Pharmaceutical composition in the form of an injectable aqueous solution including at least a rapid acting insulin analog and a glucagon suppressor with prandial action
EP3915572A1 (en) * 2020-05-29 2021-12-01 Adocia Pharmaceutical composition in the form of an injectable aqueous solution including at least a rapid acting insulin analog and a glucagon suppressor with prandial action

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101237854A (zh) * 2005-05-23 2008-08-06 Sdg公司 将胰岛素输送到哺乳动物的脂构建体
CN101454019A (zh) * 2006-04-12 2009-06-10 百达尔公司 速效和长效胰岛素联合制剂
CN101778862A (zh) * 2007-08-13 2010-07-14 诺沃-诺迪斯克有限公司 快速作用的胰岛素类似物
CN103249427A (zh) * 2010-12-14 2013-08-14 诺沃—诺迪斯克有限公司 速效胰岛素联合长效胰岛素

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3316363A1 (de) 1983-05-05 1984-11-08 Deutsche Babcock Anlagen Ag, 4200 Oberhausen Walzenrost fuer muellverbrennungsanlagen
PH25772A (en) 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DK257988D0 (da) 1988-05-11 1988-05-11 Novo Industri As Nye peptider
FI913037A7 (fi) 1988-12-23 1991-06-20 Novo Nordisk As Ihmisen insuliinianalogit
IL93282A (en) 1989-02-09 1995-08-31 Lilly Co Eli Insulin analogues
DK155690D0 (da) 1990-06-28 1990-06-28 Novo Nordisk As Nye peptider
WO2003094951A1 (en) * 2002-05-07 2003-11-20 Novo Nordisk A/S Soluble formulations comprising insulin aspart and insulin detemir
CA2609402C (en) * 2005-05-23 2014-10-21 Sdg, Inc. Lipid construct for delivery of insulin to a mammal
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
WO2007041481A1 (en) 2005-09-29 2007-04-12 Biodel, Inc. Rapid acting and prolonged acting insulin preparations
US7713929B2 (en) * 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
EP2012817A2 (en) 2006-04-12 2009-01-14 Biodel, Inc. Rapid acting and long acting insulin combination formulations
CN101796071A (zh) 2007-08-13 2010-08-04 诺沃-诺迪斯克有限公司 快速作用的胰岛素类似物
WO2011094632A1 (en) 2010-01-29 2011-08-04 The Uab Research Foundation Method for administration of insulin and pharmaceutical composition thereof
CN103889442B (zh) 2011-08-10 2016-12-28 阿道恰公司 至少一种基础胰岛素的可注射溶液

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101237854A (zh) * 2005-05-23 2008-08-06 Sdg公司 将胰岛素输送到哺乳动物的脂构建体
CN101454019A (zh) * 2006-04-12 2009-06-10 百达尔公司 速效和长效胰岛素联合制剂
CN101778862A (zh) * 2007-08-13 2010-07-14 诺沃-诺迪斯克有限公司 快速作用的胰岛素类似物
CN103249427A (zh) * 2010-12-14 2013-08-14 诺沃—诺迪斯克有限公司 速效胰岛素联合长效胰岛素

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ALAN J. GARBER等: "Premixed Insulin Analogues for the Treatment of Diabetes Mellitus", 《DRUGS》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729639A (zh) * 2017-01-10 2017-05-31 鲁南制药集团股份有限公司 一种甘精胰岛素注射液及其制备方法
CN106729639B (zh) * 2017-01-10 2018-02-27 鲁南制药集团股份有限公司 一种甘精胰岛素注射液及其制备方法

Also Published As

Publication number Publication date
BR112016006963A2 (pt) 2017-08-01
IN2013MU03124A (enExample) 2015-07-31
RU2016107610A (ru) 2017-11-03
SG11201601477VA (en) 2016-04-28
WO2015044922A1 (en) 2015-04-02
AU2014326181A1 (en) 2016-03-17
EP3052114A1 (en) 2016-08-10
JP2016531847A (ja) 2016-10-13
US20160271226A1 (en) 2016-09-22

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication

Application publication date: 20160511

WW01 Invention patent application withdrawn after publication