CN105571930A - Automatic sputum liquefying instrument and sputum liquefying method thereof - Google Patents
Automatic sputum liquefying instrument and sputum liquefying method thereof Download PDFInfo
- Publication number
- CN105571930A CN105571930A CN201610034008.9A CN201610034008A CN105571930A CN 105571930 A CN105571930 A CN 105571930A CN 201610034008 A CN201610034008 A CN 201610034008A CN 105571930 A CN105571930 A CN 105571930A
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- sputum
- test tube
- pipettor
- liquefaction
- instrument
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
Abstract
The invention discloses an automatic sputum liquefying instrument and a sputum liquefying method thereof. According to the automatic sputum liquefying instrument and the sputum liquefying method thereof, in the using process, a moving arm and a mechanical arm are arranged, the moving arm is used for moving a pipette, the mechanical arm moves up and down to pump liquid, discharge the liquid and blowing and mixing the liquid uniformly, automatic sputum liquefying, sputum-culture automatic sample adding and automatic sputum liquidation liquid sub-packaging are achieved, the automatic sputum liquefying instrument can treat sixteen sputum samples within 30 min, working efficiency is improved greatly, and the instrument has the advantages that automatic operation and flux treatment are achieved, operation is easy, use is convenient, and cross contamination between the samples is avoided; direct contact can be avoided, so that the probability of personnel infection and cross-contamination of the samples is reduced, and sputum is treated fast, economically and easily. The urgent basic requirement of a clinical testing mechanism is met. The instrument is applicable to the field of medical instruments.
Description
Technical field
The present invention relates to medical instruments field, particularly relate to a kind of sputum and automatically to liquefy instrument and sputum liquefaction method thereof.
Background technology
At present, along with deepening continuously of tubercle bacillus diagnosis and detection technology and theoretical research, sample preparation has become bottleneck place of its development of restriction.Because of the singularity of sputum, in sputum, the cultivation of Much's bacillus and detection of nucleic acids have to pass through liquefaction process, in the detection of traditional Much's bacillus, it is low to there is detection efficiency in manual operation, running time is long, sample cross contamination, the deficiency of the uneven first-class aspect of sample process, not only need to spend a large amount of manpowers, material resources, financial resources, and testing result is unstable, can not meet the patient's sample and detection demand that day by day increase, greatly reduce tuberculosis and make a definite diagnosis efficiency, and medical worker directly must contact sample, the infection personnel that cause may be caused to injure.Therefore, urgently one equipment safely and effectively.
Summary of the invention
For solving the problem, the invention provides a kind ofly improve detection efficiency, the sputum that ensures to analyze quality and protection medical worker safety liquefies instrument and sputum liquefaction method thereof automatically.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of sputum liquefies instrument automatically, comprising at least one group of sputum liquefaction test tube group, is provided with pipettor in sputum liquefaction test tube group, being provided with for the transfer arm of mobile pipettor and the mechanical arm for blowing and beating mixing above pipettor.
Be further used as the improvement of technical solution of the present invention, sputum liquefaction test tube group comprises at least one group of base set and at least one kit, each base set includes the sputum sample test tube, pipettor disposed tubes, nutrient culture media test tube, the centrifuge tube that set gradually, places pipettor in pipettor disposed tubes.
Be further used as the improvement of technical solution of the present invention, hold the NaOH solution that mass percent is 4% in kit, nutrient culture media in vitro holds Improvement type Russell medium.
Be further used as the improvement of technical solution of the present invention, sputum liquefaction test tube group is fixed in specimen holder, and specimen holder is arranged on specimen holder carrying sliding stand, and the spring that specimen holder carrying sliding stand both sides are provided with for fixed sample frame carrying sliding stand draws pin.
Be further used as the improvement of technical solution of the present invention, be provided with housing outside sputum liquefaction test tube group, transfer arm and mechanical arm, in housing, be provided with the chlorination equipment for sterilizing.
Be further used as the improvement of technical solution of the present invention, chlorination equipment is uviol lamp, and pipettor is disposable syringe.
Be further used as the improvement of technical solution of the present invention, housing is also provided with lid, is provided with support bar between housing and lid.
Be further used as the improvement of technical solution of the present invention, housing is also provided with touch screen, fly shuttle button, power interface, power switch, base button, device state indicator lamp for standby operation.
Automatically liquefied by sputum the sputum liquefaction method of instrument, comprises the following steps:
A. place to comprise in sputum liquefaction test tube group and collect sputum sample, nutrient culture media, reagent;
B. move pipettor by transfer arm to move liquid in sputum liquefaction test tube group and carry out sputum liquefaction;
C. by liquid in the sputum liquefaction test tube group moving up and down piping and druming mixing of mechanical arm.
Be further used as the improvement of technical solution of the present invention, in steps A, sputum liquefaction test tube group comprises at least one group of base set and at least one kit, the sputum sample test tube for placing sputum sample, pipettor, nutrient culture media test tube, centrifuge tube is placed successively in base set, during use, pipettor is moved by transfer arm, and by the reagent that mechanical arm extracts in kit, reagent is moved to sputum sample test tube, then the liquid in sputum sample test tube moved to nutrient culture media test tube and by mechanical arm piping and druming mixing, finally nutrient culture media test tube moved to centrifuge tube.
Beneficial effect of the present invention: this sputum liquefies instrument and sputum liquefaction method thereof automatically, the transfer arm be provided with and mechanical arm are in use, pipettor is moved by transfer arm, moved up and down by mechanical arm and carry out drawing liquid, fluid and piping and druming mixing, realize the robotization liquefaction of sputum, the automatic subpackaging of Sputum culturing robotization application of sample and sputum liquefaction liquid, 16 sputum samples can be processed in sputum robotization liquefaction instrument 30min, greatly increase work efficiency, and there is automation mechanized operation, flux process, simple to operate, easy to use, sample room is without advantages such as cross pollutions, directly contact can be avoided thus the probability of reduction personnel infection and sample cross contamination, realize fast, economical, easy sputum work for the treatment of.Meet the urgent primary demand of clinical detection mechanism.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the invention will be further described:
Fig. 1 is embodiment of the present invention one-piece construction schematic diagram;
Fig. 2 is sputum liquefaction test tube group arrangement schematic diagram described in the embodiment of the present invention.
Embodiment
Be clearly and completely described below with reference to embodiment and the accompanying drawing technique effect to design of the present invention, concrete structure and generation, to understand object of the present invention, characteristic sum effect fully.Obviously; described embodiment is a part of embodiment of the present invention, instead of whole embodiment, based on embodiments of the invention; other embodiments that those skilled in the art obtains under the prerequisite not paying creative work, all belong to the scope of protection of the invention.
With reference to Fig. 1, Fig. 2, the present invention is that a kind of sputum liquefies instrument automatically, comprising at least one group of sputum liquefaction test tube group, in sputum liquefaction test tube group, be provided with pipettor 15, being provided with above pipettor 15 for the transfer arm of mobile pipettor 15 and the mechanical arm for blowing and beating mixing.
This sputum liquefies instrument and sputum liquefaction method thereof automatically, the transfer arm be provided with and mechanical arm are in use, pipettor 15 is moved by transfer arm, moved up and down by mechanical arm and carry out drawing liquid, fluid and piping and druming mixing, realize the robotization liquefaction of sputum, the automatic subpackaging of Sputum culturing robotization application of sample and sputum liquefaction liquid, there is automation mechanized operation, flux process, simple to operate, easy to use, sample room is without advantages such as cross pollutions, directly contact can be avoided thus the probability of reduction personnel infection and sample cross contamination, realize fast, economical, easy sputum work for the treatment of.Meet the urgent primary demand of clinical detection mechanism.
As the preferred embodiment of the present invention, sputum liquefaction test tube group comprises at least one group of base set 1 and at least one kit 2, each base set 1 includes the sputum sample test tube 11, pipettor disposed tubes 12, nutrient culture media test tube 13, the centrifuge tube 14 that set gradually, places pipettor 15 in pipettor disposed tubes 12.
As the preferred embodiment of the present invention, hold the NaOH solution that mass percent is 4% in kit 2, in nutrient culture media test tube 13, hold Improvement type Russell medium.
As the preferred embodiment of the present invention, sputum liquefaction test tube group is fixed in specimen holder 58, and specimen holder 58 is arranged on specimen holder carrying sliding stand 4, and the spring that specimen holder carrying sliding stand 4 both sides are provided with for fixed sample frame carrying sliding stand 4 draws pin 3.
As the preferred embodiment of the present invention, outside sputum liquefaction test tube group, transfer arm and mechanical arm, being provided with housing 5, in housing 5, being provided with the chlorination equipment for sterilizing.
As the preferred embodiment of the present invention, chlorination equipment is uviol lamp 53, and pipettor 15 is disposable syringe.
As the preferred embodiment of the present invention, housing 5 is also provided with lid 59, is provided with support bar between housing 5 and lid 59.
As the preferred embodiment of the present invention, housing 5 is also provided with touch screen 51, flies shuttle button 52, power interface 54, power switch 55, base button 56, device state indicator lamp 57 for standby operation.
Automatically liquefied by sputum the sputum liquefaction method of instrument, comprises the following steps:
A. place to comprise in sputum liquefaction test tube group and collect sputum sample, nutrient culture media, reagent;
B. move pipettor 15 by transfer arm to move liquid in sputum liquefaction test tube group and carry out sputum liquefaction;
C. by liquid in the sputum liquefaction test tube group moving up and down piping and druming mixing of mechanical arm.
As the preferred embodiment of the present invention, in steps A, sputum liquefaction test tube group comprises at least one group of base set 1 and at least one kit 2, the sputum sample test tube 11 for placing sputum sample is placed successively in base set 1, pipettor 15, nutrient culture media test tube 13, centrifuge tube 14, during use, pipettor 15 is moved by transfer arm, and by the reagent that mechanical arm extracts in kit 2, reagent is moved to sputum sample test tube 11, then the liquid in sputum sample test tube 11 moved to nutrient culture media test tube 13 and mixed by mechanical arm piping and druming, finally nutrient culture media test tube 13 is moved to centrifuge tube 14.
This sputum liquefies instrument automatically in conjunction with electromechanical automatic and integrated technique, can realize sputum sample robotization liquefaction process and robotization inoculated and cultured; Adopt automatic control system, hi-Fix control, speeds control, adaptive control, self diagnosis correction can be realized, compensate.This sputum instrument that automatically liquefies can avoid directly contact thus reduction personnel infect and the probability of sample cross contamination, realizes fast, economic, easy sputum deals with the work.
This sputum committed steps such as instrument is sputum liquefaction, the cultivation of Much's bacillus that automatically liquefy provide automatic business processing scheme, and the Automation workstation developed has the following advantages:
Integration, multi-functional: sputum liquefaction disposal system comprises the inoculated and cultured of Much's bacillus in sputum robotization liquefaction and sputum automatically, not only that sputum liquefaction is integrated with inoculated and cultured, sputum liquefaction liquid can be used for other purposes such as nucleic acid extraction simultaneously.
Flux, high-level efficiency: can process 16 sputum samples in sputum robotization liquefaction instrument 30min, artificial treatment about 2 hours, greatly increases work efficiency; The automatic liquefaction process of 16 portions of sputums, Sputum culturing automatic sample, sputum liquefaction liquid automatic subpackaging can be realized simultaneously.
Robotization, takes precautions against and infects: replace manually-operatedly having safety precaution simultaneously and arrange, reduce medical staff infection risk; There is measure and the respective design of prevention and control pollution, can avoid because liquefaction action is too fierce, mechanical part moves, moves the sample cross contamination caused in the processes such as liquid; Realize the operation of monocyte sample closed system: the supporting consumptive materials such as sputum liquefaction bottle, sputum culture flask all should have the design of anti-cross-contamination.
Standardization, accuracy is high: automatic business processing not only reduces the error that manual operation brings, and improves homogeneity and the accuracy of testing result simultaneously.Automatic sputum liquefaction disposal system mainly contains the critical systems such as sample processing system, software operation control system, supporting consumptive material or module composition, sample processing system mainly refers to the various mechanical hook-ups realizing automation mechanized operation, software operation control system has comprised program needed for operations and operation interface, and supporting consumptive material comprises the supporting consumptive material such as special sputum bottle, Sputum culturing bottle realized needed for automatic sputum liquefaction disposal system.Processing procedure comprises automatic liquid-feeding, piping and druming mixing, automatically moves liquid, step such as sputum cultivation automatic sample, sputum liquefaction liquid automatic subpackaging etc., and above step can be selected as required voluntarily, especially Sputum culturing automatic sample, sputum liquefaction liquid automatic subpackaging can be selected as required voluntarily.
There is UV germicidal system, the ultraviolet opening time can be set, after the time arrives, uviol lamp can be closed voluntarily.Need there be independent outer cover equipment perform region, ensures the isolation of operating personnel and sample.Operation interface is touch screens (button adds touch-screen), and concrete interface in conjunction with the actual demand of clinical detection unit, need require interface hommization, simple operation, smoothnessization.
The preferred embodiment of the present invention, comprise specimen holder 58, sample rack volume size to fit, containing 8 sputum liquefaction liquid reagent storage ponds, 16 Sputum samples process receiving hole, 16 sputum culture flask receiving hole, 16 liquefiers divide tubulature receiving hole, each receiving hole is mated with standard configuration consumptive material (can be general with consumptive material common on market), and space layout is reasonable.
This sputum liquefaction instrument, its main display and operation-interface are touch screens, and general user, by clicking corresponding control on touch screen, operates this instrument.In order to machine cannot operate when preventing touch screen fault, fly shuttle button in addition in addition as standby operation mode.Achieve the automatic subpackaging of the robotization liquefaction of sputum, Sputum culturing robotization application of sample and sputum liquefaction liquid, there is automation mechanized operation, flux process (realizing the automatic business processing of 16 sputums in 30min), simple to operate, easy to use, sample room without advantages such as cross pollutions, not only meet the urgent primary demand of clinical detection mechanism, simultaneously cheap, be applicable to basic unit and promote.
Certainly, the invention is not limited to above-mentioned embodiment, those of ordinary skill in the art also can make equivalent variations or replacement under the prerequisite without prejudice to spirit of the present invention, and these equivalent distortion or replacement are all included in the application's claim limited range.
Claims (10)
1. a sputum liquefies instrument automatically, it is characterized in that: comprise at least one group of sputum liquefaction test tube group, be provided with pipettor (15) in described sputum liquefaction test tube group, described pipettor (15) top is provided with for the transfer arm of mobile pipettor (15) and the mechanical arm for blowing and beating mixing.
2. sputum according to claim 1 liquefies instrument automatically, it is characterized in that: described sputum liquefaction test tube group comprises at least one group of base set (1) and at least one kit (2), each described base set (1) includes the sputum sample test tube (11), pipettor disposed tubes (12), nutrient culture media test tube (13), the centrifuge tube (14) that set gradually, places pipettor (15) in described pipettor disposed tubes (12).
3. sputum according to claim 2 liquefies instrument automatically, it is characterized in that: hold the NaOH solution that mass percent is 4% in described kit (2), holds Improvement type Russell medium in described nutrient culture media test tube (13).
4. sputum as claimed in any of claims 1 to 3 liquefies instrument automatically, it is characterized in that: described sputum liquefaction test tube group is fixed in specimen holder (58), described specimen holder (58) is arranged on specimen holder carrying sliding stand (4), and the spring that described specimen holder carrying sliding stand (4) both sides are provided with for fixed sample frame carrying sliding stand (4) draws pin (3).
5. sputum as claimed in any of claims 1 to 3 liquefies instrument automatically, it is characterized in that: being provided with housing (5) outside described sputum liquefaction test tube group, transfer arm and mechanical arm, being provided with the chlorination equipment for sterilizing in described housing (5).
6. sputum according to claim 5 liquefies instrument automatically, it is characterized in that: described chlorination equipment is uviol lamp (53), and described pipettor (15) is disposable syringe.
7. sputum according to claim 5 liquefies instrument automatically, it is characterized in that: described housing (5) is also provided with lid (59), is provided with support bar between described housing (5) and lid (59).
8. sputum according to claim 5 liquefies instrument automatically, it is characterized in that: described housing (5) is also provided with touch screen (51), fly shuttle button (52), power interface (54), power switch (55), base button (56), device state indicator lamp (57) for standby operation.
9. liquefied by sputum according to claim 1 the sputum liquefaction method of instrument automatically, it is characterized in that, comprise the following steps:
A. place to comprise in sputum liquefaction test tube group and collect sputum sample, nutrient culture media, reagent;
B. move liquid in pipettor (15) mobile sputum liquefaction test tube group by transfer arm and carry out sputum liquefaction;
C. by liquid in the sputum liquefaction test tube group moving up and down piping and druming mixing of mechanical arm.
10. sputum liquefaction method according to claim 9, it is characterized in that: in described steps A, described sputum liquefaction test tube group comprises at least one group of base set (1) and at least one kit (2), the sputum sample test tube (11) for placing sputum sample is placed successively in described base set (1), pipettor (15), nutrient culture media test tube (13), centrifuge tube (14), during use, pipettor (15) is moved by transfer arm, and by the reagent that mechanical arm extracts in kit (2), reagent is moved to sputum sample test tube (11), then the liquid in sputum sample test tube (11) moved to nutrient culture media test tube (13) and mixed by mechanical arm piping and druming, finally nutrient culture media test tube (13) is moved to centrifuge tube (14).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610034008.9A CN105571930B (en) | 2016-01-19 | 2016-01-19 | A kind of sputum liquefies instrument and its sputum liquefaction method automatically |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610034008.9A CN105571930B (en) | 2016-01-19 | 2016-01-19 | A kind of sputum liquefies instrument and its sputum liquefaction method automatically |
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| CN105571930A true CN105571930A (en) | 2016-05-11 |
| CN105571930B CN105571930B (en) | 2019-05-07 |
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| Application Number | Title | Priority Date | Filing Date |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109900539A (en) * | 2019-03-15 | 2019-06-18 | 遵义医学院附属医院 | A kind of HPV test experience biomimetic type reagent batch addition and evenly mixing device |
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| CN102243243A (en) * | 2010-05-13 | 2011-11-16 | 南京神州英诺华医疗科技有限公司 | Novel instrument for automatically processing phlegm sample |
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| WO2014150290A1 (en) * | 2013-03-15 | 2014-09-25 | Theranos, Inc. | Devices, systems and methods for sample preparation |
| CN103558071A (en) * | 2013-11-08 | 2014-02-05 | 上海微银生物技术有限公司 | Full-automatic phlegm specimen smearing instrument, system and method |
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| CN105571930B (en) | 2019-05-07 |
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Denomination of invention: An automatic sputum liquefying instrument and its sputum liquefying method Effective date of registration: 20210318 Granted publication date: 20190507 Pledgee: China Co. truction Bank Corp Guangzhou Tianhe subbranch Pledgor: GUANGZHOU DEAOU BIOTECHNOLOGY Co.,Ltd. Registration number: Y2021440000083 |
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Date of cancellation: 20221031 Granted publication date: 20190507 Pledgee: China Co. truction Bank Corp Guangzhou Tianhe subbranch Pledgor: GUANGZHOU DEAOU BIOTECHNOLOGY Co.,Ltd. Registration number: Y2021440000083 |
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