CN208984645U - Liquid channel system for liquid working station - Google Patents
Liquid channel system for liquid working station Download PDFInfo
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- CN208984645U CN208984645U CN201821426597.6U CN201821426597U CN208984645U CN 208984645 U CN208984645 U CN 208984645U CN 201821426597 U CN201821426597 U CN 201821426597U CN 208984645 U CN208984645 U CN 208984645U
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- liquid
- reagent needle
- fluid path
- perfusion tube
- path unit
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Abstract
The utility model discloses the liquid channel systems for liquid working station, comprising: cleaning solution fluid path unit, reagent needle fluid path unit and waste liquid fluid path unit；The cleaning solution fluid path unit includes cleaning solution liquid storage device and is pumped with the cleaning solution liquid storage device by the cleaning membrane of piping connection；The reagent needle fluid path unit includes the reagent needle perfusion tube being connected to the outlet end of cleaning membrane pump, the solenoid valve and plunger pump that are connected to the reagent needle of the reagent needle perfusion tube other end and are set on the reagent needle perfusion tube.The liquid channel system of the utility model is used for automation pre-treatment of the liquid working station to biological sample and medicine sample, is able to achieve the reagent addition of automation, abandons the functions such as supernatant, cleaning reagent needle.The utility model is of simple structure and low cost, operates conveniently, and liquid relief precision is high, work efficiency is high for system, has good popularization and application foreground.
Description
Technical field
The utility model relates to biology, chemical detection devices field, in particular to a kind of fluid path for liquid working station
System.
Background technique
With the rapid development of science and technology, the research work of biology, chemical laboratory is no longer around several equipment, behaviour
If making the small scale experiments of dry-eye disease, but it is a variety of in face of increasingly complex research object and growing number of sample size, use
Experimental technique carries out multipath, diversified large scale experiment.Such as the library screening, gene order-checking and genetic chip of genetics
Research, searching, identification, the screening of protein crystal, the analysis of higher structure of differential protein in terms of proteomics, there are also new
The quantity of sample handling work that the laboratories such as the extensive screening compound of medicine discovery aspect and identification are born daily increasingly increases.
And in many laboratories and R&D institution, extraction and the sample-adding of many samples are manually to operate entirely, and hand-held pipettor is general
There are four elemental motions --- and suction nozzle is set up, liquid is taken, liquid feeding, throws away suction nozzle, these are entirely by manually completing.Manual operation is deposited
In problems: a large amount of sample treatment work not only needs a large amount of manpower and material resources and time, but also due to manual operation
Many human errors are brought, so that the liquid relief accuracy of sample treatment is low, error probability is high, the stability of sample treatment and can weigh
Renaturation is poor.Manual mode of operation is no longer satisfied high efficiency, accuracy and peace required in high-throughput sample handling processes
Quan Xing.Part in experimental implementation process or overall process are realized that automatic operating has become inevitable trend.At present
Some liquid working stations system is used for reagent, sample delivery.For example, the automatic processing of biological sample and medicine sample
Before, generally require the operations such as the reagent automated using liquid working station system addition, abandoning supernatant.And existing liquid
The generally existing the degree of automation of work station is low, inconvenient for operation, structure is complicated, the cleaning of reagent needle is inconvenient, liquid relief precision is low, work
Low efficiency, it is at high cost the defects of.
Utility model content
The technical problem to be solved by the utility model is in view of the deficiency of the prior art, provide one kind to be used for
The liquid channel system at liquid working station.
In order to solve the above technical problems, the technical solution adopted in the utility model is: a kind of liquid for liquid working station
Road system, comprising: cleaning solution fluid path unit, reagent needle fluid path unit and waste liquid fluid path unit；
The cleaning solution fluid path unit includes cleaning solution liquid storage device and passes through piping connection with the cleaning solution liquid storage device
Cleaning membrane pump；
The reagent needle fluid path unit includes the reagent needle perfusion tube being connected to the outlet end of cleaning membrane pump, connect
Reagent needle in the reagent needle perfusion tube other end and the solenoid valve and plunger pump that are set on the reagent needle perfusion tube.
Preferably, the reagent needle fluid path unit include with the cleaning membrane pump outlet end be connected to it is mutual simultaneously
At least two groups of connection.
Preferably, the reagent needle fluid path unit includes the first reagent needle fluid path unit and the second reagent needle fluid path list
Member.
Preferably, the first reagent needle fluid path unit includes the internal diameter being connected to the outlet end of cleaning membrane pump
For the first reagent needle perfusion tube of 1mm, the first reagent needle that internal diameter is 1mm, the first plunger pump that range is 250uL and the first electricity
Magnet valve.
Preferably, the second reagent needle fluid path unit includes the internal diameter being connected to the outlet end of cleaning membrane pump
For the second reagent needle perfusion tube of 2mm, the second reagent needle that internal diameter is 2mm, the second plunger pump and second that range is 2500uL
Solenoid valve.
Preferably, the cleaning solution fluid path unit further includes the cleaning solution being connected to the outlet end of cleaning membrane pump
Perfusion tube, the service sink for being connected to the cleaning solution perfusion tube other end and the third being set on cleaning solution perfusion tube electricity
Magnet valve.
Preferably, the waste liquid fluid path unit includes the waste liquid perfusion tube connecting with the drain side of the service sink, connects
Be connected to the waste liquid bottle of the waste liquid perfusion tube other end and the 4th solenoid valve being set on the waste liquid perfusion tube and waste liquid every
Membrane pump.
It preferably, further include carrying the mobile mechanical arm of the reagent needle.
Preferably, the mechanical arm is two-dimentional machinery arm.
Preferably, reagent needle liquid level detector is additionally provided on the reagent needle.
The beneficial effects of the utility model are: the liquid channel system of the utility model for liquid working station to biological sample and
The automation pre-treatment of medicine sample is able to achieve the reagent addition of automation, abandons the functions such as supernatant, cleaning reagent needle.This reality
With new structure it is simple, it is low in cost, operate conveniently, liquid relief precision is high, work efficiency is high for system, has and promotes and applies well
Prospect.
Detailed description of the invention
Fig. 1 is the theory structure schematic diagram of the liquid channel system for liquid working station of the utility model.
Description of symbols:
1-cleaning solution liquid storage device；2-cleaning membranes pump；3-cleaning solution perfusion tubes；4-third solenoid valves；5-cleanings
Pond；6-waste liquid perfusion tubes；7-the four solenoid valve；8-waste liquid diaphragm pumps；9-waste liquid bottles；10-the first reagent needle perfusion tube；
11-the first solenoid valve；12-the first plunger pump；13-the first reagent needle；14-the second reagent needle perfusion tube；15-the second electricity
Magnet valve；16-the second plunger pump；17-the second reagent needle；18-reagent needle liquid level detectors.
Specific embodiment
The utility model is described in further detail below with reference to embodiment, to enable those skilled in the art's reference say
Bright book text can be implemented accordingly.
It should be appreciated that such as " having ", "comprising" and " comprising " term used herein are not precluded one or more
The presence or addition of a other elements or combinations thereof.
As shown in Figure 1, a kind of liquid channel system for liquid working station of the present embodiment, including interconnected cleaning solution
Fluid path unit, reagent needle fluid path unit and waste liquid fluid path unit；
Cleaning solution fluid path unit include cleaning solution liquid storage device 1 and with cleaning solution liquid storage device 1 by the cleaning of piping connection every
Membrane pump 2；
Reagent needle fluid path unit includes the reagent needle perfusion tube being connected to the outlet end of cleaning membrane pump 2, is connected to reagent
The reagent needle of the needle perfusion tube other end and the first solenoid valve 11 and plunger pump being set on reagent needle perfusion tube.On reagent needle also
It is provided with reagent needle liquid level detector 18.
Reagent needle fluid path unit includes at least two groups parallel with one another being connected to the outlet end of cleaning membrane pump 2.
Cleaning solution fluid path unit further includes the cleaning solution perfusion tube 3 being connected to the outlet end of cleaning membrane pump 2, is connected to clearly
The service sink 5 of 3 other end of washing lotion perfusion tube and the second solenoid valve 15 being set on cleaning solution perfusion tube 3.
Waste liquid fluid path unit includes the waste liquid perfusion tube 6 connecting with the drain side of service sink 5, is connected to waste liquid perfusion tube 6
The waste liquid bottle 9 of the other end and the third solenoid valve 4 and waste liquid diaphragm pump 8 being set on waste liquid perfusion tube 6.
The liquid channel system further includes carrying the mobile mechanical arm (being not drawn into figure) of reagent needle, can be two-dimentional machinery arm or three
Tie up mechanical arm.In an advantageous embodiment, mechanical arm is two-dimentional machinery arm.
In one embodiment, need to by the system be applied to tubercle bacillus bacterium solution carry out pre-treatment, need to sample into
The operating procedures such as supernatant, addition reagent, temperature control incubation are abandoned in row centrifugation.Functional requirement to the liquid channel system is: addition reagent
And abandon supernatant.Reagent to be added is needed to come to 4 kinds, from 20uL to 1000uL etc..In order to guarantee the precision of liquid relief amount,
Design has chosen the sampling probe, plunger pump and pipeline of 2 kinds of specifications.It is specifically shown in the following table 1:
Table 1
In this embodiment, in the liquid channel system of the utility model, reagent needle fluid path unit includes 13 liquid of the first reagent needle
17 fluid path unit of road unit and the second reagent needle.First reagent needle, 13 fluid path unit includes connecting with the outlet end of cleaning membrane pump 2
13 perfusion tube 10 of the first reagent needle, the first reagent needle 13 that internal diameter is 1mm and the range that logical internal diameter is 1mm are the of 250uL
One plunger pump 12.Second reagent needle, 17 fluid path unit includes that the internal diameter being connected to the outlet end of cleaning membrane pump 2 is the second of 2mm
The second plunger pump 16 that 17 perfusion tube 14 of reagent needle, the second reagent needle 17 that internal diameter is 2mm and range are 2500uL.
For in the embodiment to the pipetting processes of reagent 1, referring to Fig.1, to the work of the liquid channel system of the utility model
Done as step illustrated below, in order to the understanding to the utility model, detailed process is:
1, it initializes, all solenoid valves, plunger pump and diaphragm pump are closed；
2, the first reagent needle 13 is moved in reagent bottle, the first plunger pump 12 work, by reagent aspiration to the first reagent needle
13 and pipeline in (the first plunger pump 12 must not be entered)；
3, the first reagent needle 13 is moved to sample tube position, and reagent is discharged in test tube by the work of the first plunger pump 12；
4, cleaning in needle: the first reagent needle 13 is moved to cleaning station, cleaning membrane pump 2 is opened, and the first solenoid valve 11 is opened,
To being rinsed inside the first reagent needle 13；Flushing terminates, and the first solenoid valve 11 is closed, and cleaning membrane pump 2 is closed；Waste liquid diaphragm
Pump 8 is opened, and the 4th solenoid valve 7 is opened, removal waste fluid；4th solenoid valve 7 is closed, and waste liquid diaphragm pump 8 is closed.
5, clean outside needle: cleaning membrane pump 2 is opened, and third solenoid valve 4 is opened, to rushing inside the first reagent needle 13
It washes；Flushing terminates, and third solenoid valve 4 is closed, and cleaning membrane pump 2 is closed；Waste liquid diaphragm pump 8 is opened, and the three or four solenoid valve is opened,
Removal waste fluid；4th solenoid valve 7 is closed, and waste liquid diaphragm pump 8 is closed.
It is not only in the description and the implementation although the embodiments of the present invention have been disclosed as above
Listed utilization, it can be applied to various fields suitable for the present invention completely, for those skilled in the art,
Other modifications may be easily implemented, therefore without departing from the general concept defined in the claims and the equivalent scope, this reality
It is not limited to specific details with novel.
Claims (10)
1. a kind of liquid channel system for liquid working station characterized by comprising cleaning solution fluid path unit, reagent needle fluid path
Unit and waste liquid fluid path unit；
The cleaning solution fluid path unit includes cleaning solution liquid storage device and the cleaning that passes through piping connection with the cleaning solution liquid storage device
Diaphragm pump；
The reagent needle fluid path unit includes the reagent needle perfusion tube being connected to the outlet end of cleaning membrane pump, is connected to institute
The solenoid valve and plunger pump stating the reagent needle of the reagent needle perfusion tube other end and being set on the reagent needle perfusion tube.
2. the liquid channel system according to claim 1 for liquid working station, which is characterized in that the reagent needle fluid path list
Member includes at least two groups parallel with one another being connected to the outlet end of cleaning membrane pump.
3. the liquid channel system according to claim 2 for liquid working station, which is characterized in that the reagent needle fluid path list
Member includes the first reagent needle fluid path unit and the second reagent needle fluid path unit.
4. the liquid channel system according to claim 3 for liquid working station, which is characterized in that the first reagent needle liquid
Road unit includes the first reagent needle perfusion tube, the internal diameter 1mm that the internal diameter being connected to the outlet end of cleaning membrane pump is 1mm
The first reagent needle, range be 250uL the first plunger pump and the first solenoid valve.
5. the liquid channel system according to claim 4 for liquid working station, which is characterized in that the second reagent needle liquid
Road unit includes the second reagent needle perfusion tube, the internal diameter 2mm that the internal diameter being connected to the outlet end of cleaning membrane pump is 2mm
The second reagent needle, range be 2500uL the second plunger pump and second solenoid valve.
6. the liquid channel system according to claim 1 for liquid working station, which is characterized in that the cleaning solution fluid path list
Member further includes the cleaning solution perfusion tube being connected to the outlet end of cleaning membrane pump, to be connected to the cleaning solution perfusion tube another
The service sink at end and the third solenoid valve being set on the cleaning solution perfusion tube.
7. the liquid channel system according to claim 6 for liquid working station, which is characterized in that the waste liquid fluid path unit
Including connect with the drain side of the service sink waste liquid perfusion tube, be connected to the waste liquid perfusion tube other end waste liquid bottle and
The 4th solenoid valve and waste liquid diaphragm pump being set on the waste liquid perfusion tube.
8. the liquid channel system according to claim 1 for liquid working station, which is characterized in that further include carrying the examination
The mobile mechanical arm of agent needle.
9. the liquid channel system according to claim 8 for liquid working station, which is characterized in that the mechanical arm is two dimension
Mechanical arm.
10. the liquid channel system according to claim 8 for liquid working station, which is characterized in that on the reagent needle also
It is provided with reagent needle liquid level detector.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821426597.6U CN208984645U (en) | 2018-08-31 | 2018-08-31 | Liquid channel system for liquid working station |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821426597.6U CN208984645U (en) | 2018-08-31 | 2018-08-31 | Liquid channel system for liquid working station |
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| CN208984645U true CN208984645U (en) | 2019-06-14 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110551604A (en) * | 2019-08-22 | 2019-12-10 | 中国科学院苏州生物医学工程技术研究所 | automatic detection platform for clinical detection of mycobacterium tuberculosis based on ARP |
| CN112945641A (en) * | 2021-02-03 | 2021-06-11 | 中国科学院苏州生物医学工程技术研究所 | Rotary sampling device |
| CN114368722A (en) * | 2022-01-18 | 2022-04-19 | 广州科方生物技术股份有限公司 | Pipeline rapid emptying system and filling method |
-
2018
- 2018-08-31 CN CN201821426597.6U patent/CN208984645U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110551604A (en) * | 2019-08-22 | 2019-12-10 | 中国科学院苏州生物医学工程技术研究所 | automatic detection platform for clinical detection of mycobacterium tuberculosis based on ARP |
| CN112945641A (en) * | 2021-02-03 | 2021-06-11 | 中国科学院苏州生物医学工程技术研究所 | Rotary sampling device |
| CN114368722A (en) * | 2022-01-18 | 2022-04-19 | 广州科方生物技术股份有限公司 | Pipeline rapid emptying system and filling method |
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