CN108593950A - A kind of liquid automatic sample feeding device - Google Patents
A kind of liquid automatic sample feeding device Download PDFInfo
- Publication number
- CN108593950A CN108593950A CN201810254005.5A CN201810254005A CN108593950A CN 108593950 A CN108593950 A CN 108593950A CN 201810254005 A CN201810254005 A CN 201810254005A CN 108593950 A CN108593950 A CN 108593950A
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- Prior art keywords
- reagent
- module
- submodule
- needle
- feeding device
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0401—Sample carriers, cuvettes or reaction vessels
- G01N2035/0429—Sample carriers adapted for special purposes
- G01N2035/0434—Sample carriers adapted for special purposes in the form of a syringe or pipette tip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0401—Sample carriers, cuvettes or reaction vessels
- G01N2035/0437—Cleaning cuvettes or reaction vessels
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a kind of liquid automatic sample feeding devices, and there is lower layer's processing component and upper layer to be loaded component；Lower layer's processing component includes reagent modules, cleaning module, sample module and liquid circuit module, and upper layer sample-adding component includes X-axis displacement arm module, Z axis displacement arm module, reagent needle installation module；Wherein, reagent needle installation module includes abandoning supernatant submodule, the first reagent submodule, the second reagent submodule and mixing submodule, each submodule corresponds to installation, and reagent needle, each road test agent needle can be moved independently along Z-direction all the way, be sequentially completed the function of extracting supernatant, reagent adding and mixing；It interferes with each other smaller in the liquid automatic sample feeding device that this case is provided between each module, improves the efficiency and speed of sample pre-treatments, and cross contamination can be reduced.
Description
Technical field
The invention belongs to reagent analysis engineering device technique fields, and in particular to a kind of liquid automatic sample feeding device.
Background technology
Sample analysis overall process generally comprises sample collection and preparation, sample decomposition, sample purification, input mode and sample
Five links are measured, in the broadest sense, preceding four step belongs to sample pre-treatments, but for analysis worker, relates generally to
It is that sample decomposes and two links of purification, i.e. sample pre-treatments of narrow sense, the primary sample being analysed to is handled to can carry out
The state of Instrumental Analysis.Sample pre-treatments to analysis detection for it is extremely important, this is because sample pre-treatments not only expend it is whole
60% or more time of a analytic process, and main analytical error also comes from sample pre-treatments link.
It is well known that in life science, the pre-treatment of sample is very important a link, such as blood inspection
It surveys, many work are required for carrying out on preceding processing platform.In modern experimental analysis, need to analyze a large amount of samples daily, manually
Operate sample pre-treatments, while also needing to ensure analysis result high, essence, accurate, often in order to cope with heavy analysis work and
Increase human hand, finally results in and increase manpower and management cost.With substance separation, computer, Precision Machining, machine-building, from
The fast development of the technologies such as dynamicization, Sample Pretreatment Technique are also enriched constantly and are innovated, involved suction in the pre-treatment of sample
Liquid, liquid relief, liquid feeding, with liquid, drain, cleaning, sample changeover and etc. all gradually move towards automation mechanized operation, to overcome manual operations
Middle poor reproducibility and ineffective problem.
Invention content
For the shortcomings of the prior art, the purpose of the present invention is to provide a kind of liquid automatic sample dresses
It sets, realizes the automation mechanized operation for extracting supernatant, addition reagent and reagent mixing.
The present invention provides a kind of liquid automatic sample feeding devices, and there is lower layer's processing component and upper layer to be loaded component；
Lower layer's processing component includes reagent modules, cleaning module, sample module and liquid circuit module, and each module is arranged in
On rectangle chassis；Sample module and cleaning module are disposed adjacent the side long side on rectangle chassis, and reagent modules are arranged in rectangle
The side short side on rectangle chassis is arranged in the other side long side on chassis, liquid circuit module；
The upper layer sample-adding component includes X-axis displacement arm module, Z axis displacement arm module, reagent needle installation module；X-axis displacement arm mould
Block is fixed on along rectangle chassis long side above reagent modules by Z axis displacement arm module；Reagent needle installation module is equipped on X-axis displacement arm
Module and Z axis displacement arm module, and moved in X direction with Z-direction；
The reagent needle installation module includes abandoning supernatant submodule, the first reagent submodule, the second reagent submodule and mixing
Even submodule, each submodule corresponds to installation, and reagent needle, each road test agent needle can be moved independently along Z-direction, be sequentially completed all the way
Extract the function of supernatant, reagent adding and mixing.
Preferably, the reagent modules include reagent bottle and waste liquid bottle.
Preferably, the cleaning module includes cleaning needle and service sink, for carrying out cleaning operation to each road test agent needle.
Preferably, the sample module is disposed with one group of rack for test tube corresponding to each road test agent needle.
Preferably, the liquid circuit module includes isolating valve, diaphragm pump and peristaltic pump.
Preferably, the supernatant submodule of abandoning includes isolating valve, isolation film and test tube level sensor, for extracting one
In quantitative supernatant to waste liquid bottle.
Preferably, the first reagent submodule and the second reagent submodule include reagent bottle, peristaltic pump, are used for from examination
A certain amount of reagent is extracted in agent bottle to be added in test tube.
Preferably, the mixing submodule includes air pump, air filter, air accumulator, drier and pressure regulator valve, is used
In being blown into a certain amount of air to test tube liquid level.
The beneficial effects of the invention are as follows：Liquid automatic sample feeding device provided by the invention can realize the pumping of sample supernatant
It takes, the functions such as the addition of at least two different reagents and reagent mixing, which is to abandon supernatant by install reagent needle
Module, the first reagent submodule, the second reagent submodule and mixing submodule independently move up and down and realize in z-direction,
Each way module drives corresponding reagent needle self-movement, interferes with each other smaller between each function module, and it is automatic to improve liquid
The efficiency and speed of sample-adding, and cross contamination can be reduced.
Description of the drawings
Fig. 1 is the structural schematic diagram of liquid automatic sample feeding device；
Fig. 2 is the structural schematic diagram that upper layer is loaded component；
Wherein, the upper layers 1- sample-adding component, 2- lower layers processing component, 11-X axis displacement arm module, 12-Z axis displacement arm module, 13-
Reagent needle installs module, 14- reagents needle, 21- reagent modules, 22- cleaning modules, 23- samples module, 24- liquid circuit modules.
Specific implementation mode
Present invention will be described in further detail below with reference to the accompanying drawings, to enable those skilled in the art with reference to specification text
Word can be implemented according to this.
The liquid automatic sample feeding device that this case is related to includes upper layer sample-adding component 1 and lower layer's processing component 2, wherein upper layer
It includes that X-axis displacement arm module 11, Z axis displacement arm module 12 and reagent needle install module 13 to be loaded component 1, and X-axis displacement arm module 11 passes through Z
Axis displacement arm module 12 is fixed on along rectangle chassis long side above reagent modules 21, and reagent needle installation module 13 is equipped on X-axis displacement arm
Module 11 and Z axis displacement arm module 12, can realize the movement of X-direction and Z-direction；
Reagent needle installation module 13 includes abandoning supernatant submodule, the first reagent submodule, the second reagent submodule and mixing
Submodule, each submodule correspond to installation reagent needle 14 all the way, and each road test agent needle 14 can independently move up and down along Z-direction, according to
The secondary function of completing to extract supernatant, reagent adding and mixing；Wherein, it includes isolating valve, isolation film and examination to abandon supernatant submodule
Pipe level sensor, for extracting in a certain amount of supernatant to waste liquid bottle；First reagent submodule and the second reagent submodule packet
Reagent bottle, peristaltic pump are included, for being added in test tube from extracting a certain amount of reagent in reagent bottle；Mixing submodule include air pump,
Air filter, air accumulator, drier and pressure regulator valve make solvent in test tube for being blown into a certain amount of air to test tube liquid level
It is uniformly mixed；
Lower layer's processing component includes reagent modules 21, cleaning module 22, sample module 23 and liquid circuit module 24, each module row
Cloth is on rectangle chassis；Sample module 23 and cleaning module 22 are disposed adjacent the side long side on rectangle chassis, reagent modules 21
Other side long side on rectangle chassis is set, and the side short side on rectangle chassis is arranged in liquid circuit module 23；Wherein, reagent modules 21
Including reagent bottle and waste liquid bottle, cleaning module 22 includes cleaning needle and service sink, for carrying out cleaning behaviour to each road test agent needle 14
Make, sample module 23 is disposed with one group of rack for test tube corresponding to each road test agent needle 14, after centrifugation is mounted on rack for test tube
Sample tube (has been raised one's hat), and liquid circuit module 24 includes isolating valve, diaphragm pump and peristaltic pump.
Although the embodiments of the present invention have been disclosed as above, but its is not only in the description and the implementation listed
With it can be fully applied to various fields suitable for the present invention, for those skilled in the art, can be easily
Realize other modification, therefore without departing from the general concept defined in the claims and the equivalent scope, the present invention is simultaneously unlimited
In specific details and legend shown and described herein.
Claims (8)
1. a kind of liquid automatic sample feeding device, which is characterized in that have lower layer's processing component and upper layer to be loaded component；
Lower layer's processing component includes reagent modules, cleaning module, sample module and liquid circuit module, and each module is arranged in rectangle
On chassis；Sample module and cleaning module are disposed adjacent the side long side on rectangle chassis, and reagent modules are arranged on rectangle chassis
Other side long side, the side short side on rectangle chassis is arranged in liquid circuit module；
The upper layer sample-adding component includes X-axis displacement arm module, Z axis displacement arm module, reagent needle installation module；X-axis displacement arm module is logical
Z axis displacement arm module is crossed to be fixed on above reagent modules along rectangle chassis long side；Reagent needle installation module is equipped on X-axis displacement arm module
With Z axis displacement arm module, and in X direction with Z-direction move；
The reagent needle installation module includes abandoning supernatant submodule, the first reagent submodule, the second reagent submodule and mixing
Module, each submodule corresponds to installation, and reagent needle, each road test agent needle can be moved independently along Z-direction all the way, be sequentially completed extraction
The function of supernatant, reagent adding and mixing.
2. automatic sample feeding device according to claim 1, which is characterized in that the reagent modules include reagent bottle and waste liquid
Bottle.
3. according to claim 1 automatic sample feeding device, which is characterized in that the cleaning module includes cleaning needle and cleaning
Pond, for carrying out cleaning operation to each road test agent needle.
4. automatic sample feeding device according to claim 1, which is characterized in that the sample module corresponds to each road test agent
Needle is disposed with one group of rack for test tube.
5. automatic sample feeding device according to claim 1, which is characterized in that the liquid circuit module includes isolating valve, diaphragm
Pump and peristaltic pump.
6. automatic sample feeding device according to claim 1, which is characterized in that it is described abandon supernatant submodule include isolating valve,
Isolation film and test tube level sensor, for extracting in a certain amount of supernatant to waste liquid bottle.
7. automatic sample feeding device according to claim 1, which is characterized in that the first reagent submodule and the second reagent
Submodule includes reagent bottle, peristaltic pump, for being added in test tube from extracting a certain amount of reagent in reagent bottle.
8. automatic sample feeding device according to claim 1, which is characterized in that the mixing submodule includes air pump, sky
Air filter, air accumulator, drier and pressure regulator valve, for being blown into a certain amount of air to test tube liquid level.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810254005.5A CN108593950A (en) | 2018-03-26 | 2018-03-26 | A kind of liquid automatic sample feeding device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810254005.5A CN108593950A (en) | 2018-03-26 | 2018-03-26 | A kind of liquid automatic sample feeding device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108593950A true CN108593950A (en) | 2018-09-28 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810254005.5A Pending CN108593950A (en) | 2018-03-26 | 2018-03-26 | A kind of liquid automatic sample feeding device |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109254007A (en) * | 2018-11-08 | 2019-01-22 | 深圳市瑞图生物技术有限公司 | Gynecological secretion detection device |
| CN109470330A (en) * | 2018-12-04 | 2019-03-15 | 佛山科学技术学院 | A kind of condenser type biological reagent liquid level sensor and control method |
| CN110057969A (en) * | 2019-05-28 | 2019-07-26 | 菏泽学院 | A kind of BOD5Measure automatic medicine adding apparatus |
| CN110551604A (en) * | 2019-08-22 | 2019-12-10 | 中国科学院苏州生物医学工程技术研究所 | automatic detection platform for clinical detection of mycobacterium tuberculosis based on ARP |
| CN113252862A (en) * | 2021-07-14 | 2021-08-13 | 四川久环环境技术有限责任公司 | Water quality monitoring station |
| CN115430474A (en) * | 2022-11-08 | 2022-12-06 | 山东康华生物医疗科技股份有限公司 | Frame is stored with reagent to gold mark appearance |
| WO2024149074A1 (en) * | 2023-01-13 | 2024-07-18 | 深圳市真迈生物科技有限公司 | Reagent extraction apparatus and sequencing system |
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| WO2008043463A1 (en) * | 2006-10-10 | 2008-04-17 | Hte Ag The High Throughput Experimentation Company | Device and method for producing substance formulations - formulation station |
| CN201382946Y (en) * | 2009-04-17 | 2010-01-13 | 武汉医尔特科技有限公司 | Novel full-automatic blood analyzer |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109254007A (en) * | 2018-11-08 | 2019-01-22 | 深圳市瑞图生物技术有限公司 | Gynecological secretion detection device |
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| CN109470330A (en) * | 2018-12-04 | 2019-03-15 | 佛山科学技术学院 | A kind of condenser type biological reagent liquid level sensor and control method |
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| CN110057969A (en) * | 2019-05-28 | 2019-07-26 | 菏泽学院 | A kind of BOD5Measure automatic medicine adding apparatus |
| CN110057969B (en) * | 2019-05-28 | 2023-12-22 | 菏泽学院 | BOD (BOD) 5 Automatic dosing device for measurement |
| CN110551604A (en) * | 2019-08-22 | 2019-12-10 | 中国科学院苏州生物医学工程技术研究所 | automatic detection platform for clinical detection of mycobacterium tuberculosis based on ARP |
| CN113252862A (en) * | 2021-07-14 | 2021-08-13 | 四川久环环境技术有限责任公司 | Water quality monitoring station |
| CN113252862B (en) * | 2021-07-14 | 2021-09-17 | 四川久环环境技术有限责任公司 | Water quality monitoring station |
| CN115430474A (en) * | 2022-11-08 | 2022-12-06 | 山东康华生物医疗科技股份有限公司 | Frame is stored with reagent to gold mark appearance |
| WO2024149074A1 (en) * | 2023-01-13 | 2024-07-18 | 深圳市真迈生物科技有限公司 | Reagent extraction apparatus and sequencing system |
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Application publication date: 20180928 |
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