CN105561273A - Traditional Chinese medicine composition for treating intestinal tract stress syndromes and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating intestinal tract stress syndromes and preparation method thereof Download PDFInfo
- Publication number
- CN105561273A CN105561273A CN201610056107.7A CN201610056107A CN105561273A CN 105561273 A CN105561273 A CN 105561273A CN 201610056107 A CN201610056107 A CN 201610056107A CN 105561273 A CN105561273 A CN 105561273A
- Authority
- CN
- China
- Prior art keywords
- radix
- weight portion
- parts
- chinese medicine
- medicine composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 58
- 208000011580 syndromic disease Diseases 0.000 title claims abstract description 28
- 239000000203 mixture Substances 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 210000001035 gastrointestinal tract Anatomy 0.000 title abstract description 6
- 239000009636 Huang Qi Substances 0.000 claims abstract description 16
- 241000218176 Corydalis Species 0.000 claims abstract description 14
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 14
- 235000006886 Zingiber officinale Nutrition 0.000 claims abstract description 5
- 235000008397 ginger Nutrition 0.000 claims abstract description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 32
- 230000000968 intestinal effect Effects 0.000 claims description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- 239000000706 filtrate Substances 0.000 claims description 16
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 12
- 238000005325 percolation Methods 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 8
- 238000003756 stirring Methods 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 7
- 239000012530 fluid Substances 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 5
- 241000234314 Zingiber Species 0.000 claims description 4
- 238000003556 assay Methods 0.000 claims description 4
- 230000006837 decompression Effects 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- -1 filtration Substances 0.000 claims description 4
- 239000012467 final product Substances 0.000 claims description 4
- 239000003921 oil Substances 0.000 claims description 4
- 238000011084 recovery Methods 0.000 claims description 4
- 238000004064 recycling Methods 0.000 claims description 4
- 239000002904 solvent Substances 0.000 claims description 4
- 230000001954 sterilising effect Effects 0.000 claims description 4
- 239000000341 volatile oil Substances 0.000 claims description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 31
- 201000010099 disease Diseases 0.000 abstract description 29
- 230000000694 effects Effects 0.000 abstract description 25
- 238000011282 treatment Methods 0.000 abstract description 24
- 229940079593 drug Drugs 0.000 abstract description 17
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 238000003672 processing method Methods 0.000 abstract description 2
- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 244000273928 Zingiber officinale Species 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 210000000952 spleen Anatomy 0.000 description 51
- 230000036407 pain Effects 0.000 description 34
- 208000002193 Pain Diseases 0.000 description 33
- 210000002784 stomach Anatomy 0.000 description 32
- 210000004072 lung Anatomy 0.000 description 28
- 239000008280 blood Substances 0.000 description 25
- 210000004369 blood Anatomy 0.000 description 24
- 230000007812 deficiency Effects 0.000 description 23
- 206010012735 Diarrhoea Diseases 0.000 description 21
- 210000004185 liver Anatomy 0.000 description 19
- 230000001737 promoting effect Effects 0.000 description 18
- 230000001717 pathogenic effect Effects 0.000 description 15
- 208000004880 Polyuria Diseases 0.000 description 11
- 210000000038 chest Anatomy 0.000 description 11
- 230000035619 diuresis Effects 0.000 description 11
- 210000000936 intestine Anatomy 0.000 description 11
- 206010011224 Cough Diseases 0.000 description 10
- 230000004087 circulation Effects 0.000 description 10
- 235000013305 food Nutrition 0.000 description 10
- 238000005728 strengthening Methods 0.000 description 10
- 210000001124 body fluid Anatomy 0.000 description 9
- 239000010839 body fluid Substances 0.000 description 9
- 235000009508 confectionery Nutrition 0.000 description 9
- 201000006549 dyspepsia Diseases 0.000 description 9
- 206010000087 Abdominal pain upper Diseases 0.000 description 8
- 206010030113 Oedema Diseases 0.000 description 8
- 210000001015 abdomen Anatomy 0.000 description 8
- 210000002216 heart Anatomy 0.000 description 8
- 230000001105 regulatory effect Effects 0.000 description 8
- 206010062717 Increased upper airway secretion Diseases 0.000 description 7
- 210000003414 extremity Anatomy 0.000 description 7
- 210000003734 kidney Anatomy 0.000 description 7
- 208000026435 phlegm Diseases 0.000 description 7
- 208000004998 Abdominal Pain Diseases 0.000 description 6
- 208000006820 Arthralgia Diseases 0.000 description 6
- 206010047700 Vomiting Diseases 0.000 description 6
- 230000036528 appetite Effects 0.000 description 6
- 235000019789 appetite Nutrition 0.000 description 6
- 230000017531 blood circulation Effects 0.000 description 6
- 210000000481 breast Anatomy 0.000 description 6
- 230000014759 maintenance of location Effects 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 244000052769 pathogen Species 0.000 description 6
- 208000037920 primary disease Diseases 0.000 description 6
- 230000002269 spontaneous effect Effects 0.000 description 6
- 230000008673 vomiting Effects 0.000 description 6
- 208000001431 Psychomotor Agitation Diseases 0.000 description 5
- 206010038743 Restlessness Diseases 0.000 description 5
- 208000033809 Suppuration Diseases 0.000 description 5
- 239000002775 capsule Substances 0.000 description 5
- 208000001848 dysentery Diseases 0.000 description 5
- 239000003172 expectorant agent Substances 0.000 description 5
- 230000003419 expectorant effect Effects 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 230000009545 invasion Effects 0.000 description 5
- 239000006187 pill Substances 0.000 description 5
- 210000000582 semen Anatomy 0.000 description 5
- 239000009765 shen ling bai zhu Substances 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 238000010792 warming Methods 0.000 description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 4
- 206010010774 Constipation Diseases 0.000 description 4
- 206010010904 Convulsion Diseases 0.000 description 4
- 206010067715 Gastrointestinal sounds abnormal Diseases 0.000 description 4
- 206010019233 Headaches Diseases 0.000 description 4
- 206010033557 Palpitations Diseases 0.000 description 4
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 208000019790 abdominal distention Diseases 0.000 description 4
- 230000009471 action Effects 0.000 description 4
- 208000019902 chronic diarrheal disease Diseases 0.000 description 4
- 230000001684 chronic effect Effects 0.000 description 4
- 230000036461 convulsion Effects 0.000 description 4
- 206010061428 decreased appetite Diseases 0.000 description 4
- 231100000869 headache Toxicity 0.000 description 4
- 206010022437 insomnia Diseases 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 210000003205 muscle Anatomy 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 230000035807 sensation Effects 0.000 description 4
- 235000019615 sensations Nutrition 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 230000035922 thirst Effects 0.000 description 4
- 210000001835 viscera Anatomy 0.000 description 4
- 239000009571 yupingfeng Substances 0.000 description 4
- 206010002383 Angina Pectoris Diseases 0.000 description 3
- 208000002881 Colic Diseases 0.000 description 3
- 241000721047 Danaus plexippus Species 0.000 description 3
- 208000008454 Hyperhidrosis Diseases 0.000 description 3
- 208000019255 Menstrual disease Diseases 0.000 description 3
- 206010037660 Pyrexia Diseases 0.000 description 3
- AEQDJSLRWYMAQI-UHFFFAOYSA-N Tetrahydropalmatine Natural products C1CN2CC(C(=C(OC)C=C3)OC)=C3CC2C2=C1C=C(OC)C(OC)=C2 AEQDJSLRWYMAQI-UHFFFAOYSA-N 0.000 description 3
- 230000002159 abnormal effect Effects 0.000 description 3
- 238000009825 accumulation Methods 0.000 description 3
- 230000002411 adverse Effects 0.000 description 3
- DCSUBABJRXZOMT-IRLDBZIGSA-N cisapride Chemical compound C([C@@H]([C@@H](CC1)NC(=O)C=2C(=CC(N)=C(Cl)C=2)OC)OC)N1CCCOC1=CC=C(F)C=C1 DCSUBABJRXZOMT-IRLDBZIGSA-N 0.000 description 3
- 229960005132 cisapride Drugs 0.000 description 3
- DCSUBABJRXZOMT-UHFFFAOYSA-N cisapride Natural products C1CC(NC(=O)C=2C(=CC(N)=C(Cl)C=2)OC)C(OC)CN1CCCOC1=CC=C(F)C=C1 DCSUBABJRXZOMT-UHFFFAOYSA-N 0.000 description 3
- 210000000232 gallbladder Anatomy 0.000 description 3
- 230000002496 gastric effect Effects 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 210000002429 large intestine Anatomy 0.000 description 3
- 230000033001 locomotion Effects 0.000 description 3
- 230000000144 pharmacologic effect Effects 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 230000004936 stimulating effect Effects 0.000 description 3
- 210000002435 tendon Anatomy 0.000 description 3
- AEQDJSLRWYMAQI-KRWDZBQOSA-N tetrahydropalmatine Chemical compound C1CN2CC(C(=C(OC)C=C3)OC)=C3C[C@H]2C2=C1C=C(OC)C(OC)=C2 AEQDJSLRWYMAQI-KRWDZBQOSA-N 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 206010000060 Abdominal distension Diseases 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 2
- 201000000736 Amenorrhea Diseases 0.000 description 2
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 206010008631 Cholera Diseases 0.000 description 2
- RFKQJTRWODZPHF-UHFFFAOYSA-N Dehydrocorydaline Chemical compound COC1=C(OC)C=C2CC[N+]3=CC4=C(OC)C(OC)=CC=C4C(C)=C3C2=C1 RFKQJTRWODZPHF-UHFFFAOYSA-N 0.000 description 2
- 208000005171 Dysmenorrhea Diseases 0.000 description 2
- 206010013935 Dysmenorrhoea Diseases 0.000 description 2
- 206010013954 Dysphoria Diseases 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- 206010019468 Hemiplegia Diseases 0.000 description 2
- 206010022998 Irritability Diseases 0.000 description 2
- 206010027514 Metrorrhagia Diseases 0.000 description 2
- 206010028372 Muscular weakness Diseases 0.000 description 2
- 206010068319 Oropharyngeal pain Diseases 0.000 description 2
- 201000007100 Pharyngitis Diseases 0.000 description 2
- 206010040007 Sense of oppression Diseases 0.000 description 2
- 208000012886 Vertigo Diseases 0.000 description 2
- 208000005946 Xerostomia Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 201000009840 acute diarrhea Diseases 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 231100000540 amenorrhea Toxicity 0.000 description 2
- 208000007502 anemia Diseases 0.000 description 2
- 208000022531 anorexia Diseases 0.000 description 2
- 230000001142 anti-diarrhea Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- VRSRXLJTYQVOHC-YEJXKQKISA-N corydaline Chemical compound C=1([C@H]2[C@H]3C)C=C(OC)C(OC)=CC=1CCN2CC1=C3C=CC(OC)=C1OC VRSRXLJTYQVOHC-YEJXKQKISA-N 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 208000017574 dry cough Diseases 0.000 description 2
- 206010013781 dry mouth Diseases 0.000 description 2
- 230000004064 dysfunction Effects 0.000 description 2
- 206010016256 fatigue Diseases 0.000 description 2
- 210000004211 gastric acid Anatomy 0.000 description 2
- 230000027119 gastric acid secretion Effects 0.000 description 2
- 208000021302 gastroesophageal reflux disease Diseases 0.000 description 2
- 230000007160 gastrointestinal dysfunction Effects 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 208000035861 hematochezia Diseases 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- 230000002218 hypoglycaemic effect Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 239000002398 materia medica Substances 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000003340 mental effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000036473 myasthenia Effects 0.000 description 2
- 206010029410 night sweats Diseases 0.000 description 2
- 230000036565 night sweats Effects 0.000 description 2
- 231100000862 numbness Toxicity 0.000 description 2
- 239000002304 perfume Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 230000003014 reinforcing effect Effects 0.000 description 2
- 235000013599 spices Nutrition 0.000 description 2
- 235000021259 spicy food Nutrition 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 210000001113 umbilicus Anatomy 0.000 description 2
- 231100000889 vertigo Toxicity 0.000 description 2
- 208000016254 weariness Diseases 0.000 description 2
- 210000000707 wrist Anatomy 0.000 description 2
- KZJWDPNRJALLNS-VPUBHVLGSA-N (-)-beta-Sitosterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@@H](C(C)C)CC)C)CC4)CC3)CC=2)CC1 KZJWDPNRJALLNS-VPUBHVLGSA-N 0.000 description 1
- CSVWWLUMXNHWSU-UHFFFAOYSA-N (22E)-(24xi)-24-ethyl-5alpha-cholest-22-en-3beta-ol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(CC)C(C)C)C1(C)CC2 CSVWWLUMXNHWSU-UHFFFAOYSA-N 0.000 description 1
- DNXIKVLOVZVMQF-UHFFFAOYSA-N (3beta,16beta,17alpha,18beta,20alpha)-17-hydroxy-11-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(C(=O)OC)C(O)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 DNXIKVLOVZVMQF-UHFFFAOYSA-N 0.000 description 1
- FUFLCEKSBBHCMO-UHFFFAOYSA-N 11-dehydrocorticosterone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 FUFLCEKSBBHCMO-UHFFFAOYSA-N 0.000 description 1
- KLEXDBGYSOIREE-UHFFFAOYSA-N 24xi-n-propylcholesterol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CCC)C(C)C)C1(C)CC2 KLEXDBGYSOIREE-UHFFFAOYSA-N 0.000 description 1
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 208000007848 Alcoholism Diseases 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 241000244186 Ascaris Species 0.000 description 1
- 206010003591 Ataxia Diseases 0.000 description 1
- 206010063659 Aversion Diseases 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 208000003569 Central serous chorioretinopathy Diseases 0.000 description 1
- LPZCCMIISIBREI-MTFRKTCUSA-N Citrostadienol Natural products CC=C(CC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4[C@H](C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C LPZCCMIISIBREI-MTFRKTCUSA-N 0.000 description 1
- 241000756943 Codonopsis Species 0.000 description 1
- 206010010144 Completed suicide Diseases 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 206010010947 Coordination abnormal Diseases 0.000 description 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 description 1
- MFYSYFVPBJMHGN-UHFFFAOYSA-N Cortisone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)(O)C(=O)CO)C4C3CCC2=C1 MFYSYFVPBJMHGN-UHFFFAOYSA-N 0.000 description 1
- VRSRXLJTYQVOHC-UHFFFAOYSA-N Corydaline Natural products CC1C2C=3C=C(OC)C(OC)=CC=3CCN2CC2=C1C=CC(OC)=C2OC VRSRXLJTYQVOHC-UHFFFAOYSA-N 0.000 description 1
- 208000019505 Deglutition disease Diseases 0.000 description 1
- ARVGMISWLZPBCH-UHFFFAOYSA-N Dehydro-beta-sitosterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)CCC(CC)C(C)C)CCC33)C)C3=CC=C21 ARVGMISWLZPBCH-UHFFFAOYSA-N 0.000 description 1
- 206010012335 Dependence Diseases 0.000 description 1
- 208000036649 Dysbacteriosis Diseases 0.000 description 1
- 208000027244 Dysbiosis Diseases 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 206010016807 Fluid retention Diseases 0.000 description 1
- 102100021022 Gastrin Human genes 0.000 description 1
- 108010052343 Gastrins Proteins 0.000 description 1
- 208000007882 Gastritis Diseases 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 241000202807 Glycyrrhiza Species 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 208000032139 Halitosis Diseases 0.000 description 1
- 240000008669 Hedera helix Species 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 206010049077 Hernia pain Diseases 0.000 description 1
- 208000015817 Infant Nutrition disease Diseases 0.000 description 1
- 206010024642 Listless Diseases 0.000 description 1
- 206010028140 Mucous stools Diseases 0.000 description 1
- 206010062575 Muscle contracture Diseases 0.000 description 1
- 206010030302 Oliguria Diseases 0.000 description 1
- 240000002948 Ophiopogon intermedius Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 102000057297 Pepsin A Human genes 0.000 description 1
- 108090000284 Pepsin A Proteins 0.000 description 1
- 206010034568 Peripheral coldness Diseases 0.000 description 1
- 208000012287 Prolapse Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- LCQMZZCPPSWADO-UHFFFAOYSA-N Reserpilin Natural products COC(=O)C1COCC2CN3CCc4c([nH]c5cc(OC)c(OC)cc45)C3CC12 LCQMZZCPPSWADO-UHFFFAOYSA-N 0.000 description 1
- QEVHRUUCFGRFIF-SFWBKIHZSA-N Reserpine Natural products O=C(OC)[C@@H]1[C@H](OC)[C@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)C[C@H]2[C@@H]1C[C@H]1N(C2)CCc2c3c([nH]c12)cc(OC)cc3 QEVHRUUCFGRFIF-SFWBKIHZSA-N 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 241000195474 Sargassum Species 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 208000001203 Smallpox Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- 206010043376 Tetanus Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 206010046814 Uterine prolapse Diseases 0.000 description 1
- 241000870995 Variola Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000009257 Visceral Prolapse Diseases 0.000 description 1
- 206010063840 Visceroptosis Diseases 0.000 description 1
- 208000000260 Warts Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 201000004484 acute conjunctivitis Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 210000004100 adrenal gland Anatomy 0.000 description 1
- 201000007930 alcohol dependence Diseases 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 229940024606 amino acid Drugs 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000001166 anti-perspirative effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000000767 anti-ulcer Effects 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 201000009361 ascariasis Diseases 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- MJVXAPPOFPTTCA-UHFFFAOYSA-N beta-Sistosterol Natural products CCC(CCC(C)C1CCC2C3CC=C4C(C)C(O)CCC4(C)C3CCC12C)C(C)C MJVXAPPOFPTTCA-UHFFFAOYSA-N 0.000 description 1
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 description 1
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 description 1
- 210000003445 biliary tract Anatomy 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000002051 biphasic effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 210000003710 cerebral cortex Anatomy 0.000 description 1
- AOXOCDRNSPFDPE-UKEONUMOSA-N chembl413654 Chemical compound C([C@H](C(=O)NCC(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@@H](N)CCC(O)=O)C1=CC=C(O)C=C1 AOXOCDRNSPFDPE-UKEONUMOSA-N 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 208000023652 chronic gastritis Diseases 0.000 description 1
- 208000024035 chronic otitis media Diseases 0.000 description 1
- 235000021270 cold food Nutrition 0.000 description 1
- 206010009887 colitis Diseases 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 208000006111 contracture Diseases 0.000 description 1
- 229960004544 cortisone Drugs 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 208000013219 diaphoresis Diseases 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000007140 dysbiosis Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000002964 excitative effect Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 201000005917 gastric ulcer Diseases 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- 230000005176 gastrointestinal motility Effects 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229960001031 glucose Drugs 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 230000002607 hemopoietic effect Effects 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 230000000147 hypnotic effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 208000016290 incoordination Diseases 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 208000002551 irritable bowel syndrome Diseases 0.000 description 1
- 210000004153 islets of langerhan Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 210000000337 motor cortex Anatomy 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 description 1
- 229960003147 reserpine Drugs 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 230000002000 scavenging effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
- 229950005143 sitosterol Drugs 0.000 description 1
- NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 description 1
- 235000015500 sitosterol Nutrition 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 201000010153 skin papilloma Diseases 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 230000035943 smell Effects 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 229930002600 steroidal saponin Natural products 0.000 description 1
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 description 1
- 235000021286 stilbenes Nutrition 0.000 description 1
- 230000004206 stomach function Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition for treating intestinal tract stress syndromes. The traditional Chinese medicine composition is prepared from, by weight, 3-5 parts of radix astragali, 8-10 parts of rhizoma atractylodis macrocephalae, 3-5 parts of radix saposhnikoviae, 8-10 parts of rhizoma atractylodis macrocephalae, 3-5 parts of radix bupleuri, 3-5 parts of fructus aurantii, 3-5 parts of rhizoma corydalis, 1-2 parts of fructus mume, 3-5 parts of radix ophiopogonis, 3-5 parts of red-rooted salvia roots, 1-2 parts of fructus amomi rotundus, 1-2 parts of green tangerine peel, 1-2 parts of poria, 1-2 parts of dried ginger and 1-2 parts of radix glycyrrhizae. The traditional Chinese medicine composition preparation process is researched according to different features of drugs, different processing methods are adopted, reasonable combination is conducted, the comprehensive treatment effects of all constituents of medicinal raw materials are maintained sufficiently, the medicine is made to directly act on the local disease position, the treatment effect is achieved rapidly, no toxic or side effect exists, and the traditional Chinese medicine composition is good in mouthfeel and can be accepted by patients easily.
Description
Technical field
The invention belongs to technical field of Chinese medicines, being specifically related to a kind of intestinal for the treatment of stress the Chinese medicine composition of syndrome and preparation method.
Background technology
Intestinal stress syndrome be that one changes relevant with gastrointestinal function, abnormal for cardinal symptom and the syndrome lacking gastrointestinal tract structure or biochemical exception with chronic or RAP, diarrhoea, bowl evacuation habit and stool, normal and other functional diseases of gastrointestinal tract such as gastro oesophageal reflux disease (GORD) and functional dyspepsia exist simultaneously.Needing can cause the organic disease of these symptoms through checking to get rid of. primary disease belongs to gastrointestinal dysfunction disease, comprise stomachache, abdominal distention, bowl evacuation habit and stool exception, Mucous Stool, sustainable existence or interval outbreak, and lack the syndrome that morphology and biochemical abnormal change can provide explanation.It is characterized in that the Yi Jixing of function of intestinal canal.
Intestinal stress syndrome at present at the sickness rate of China at about 10%-20%, patient based on 20-40 year young and middle-aged, women's common (more having some patients to occur left lower quadrant dull pain); Have the tendency of recurrent exerbation, normal delay is difficult.At drug treatment, doctor trained in Western medicine is temporarily without desirable medicine, and this disease of Chinese traditional treatment has a clear superiority in.Intestinal stress the definite mechanism of causing a disease of syndrome now still indefinite, but psychologic factors is the key factor causing falling ill, and has a strong impact on patients ' life quality.
Chinese medicine is thought: the primary disease cause of disease belongs to the category such as " sympotoms caused by cold factors ", " stomachache ", " strongly fragrant disease ", and primary disease is mainly air-cooled with diseases caused by exogenous pathogenic factor cold-evil, invasion and attack with in, or cold stagnant resistance knot gastral cavilty, or addiction to uncooked and cold food is too, and middle-jiao yang, function of the spleen and stomach is cut down, cause ascending or descending movement of vital Qi not normal, YIN-cold Inner contains and forms primary disease.Cold many by innate deficiency of YANG in the body from interior life, spleen sun is not transported, and alvus is empty and have cold; Or because of deficiency of YANG of middle-JIAO hungry, cold-damp is stagnated, or because of insufficiency of vital energy and blood, alvus loses its replenishing vital QI with drugs of warm nature and causes a disease.Congestion resistance network irritability stasis, or prolonged illness delay, disease enters network for a long time; Or cold-evil stagnates, QI-blood circulation is smooth and cause congestion resistance network and become primary disease.
Treatment intestinal stress be mainly contained to the treatments by Chinese herbs such as Shenlingbaizhu pills or applies Western medicine live triple capsule and gastrointestinal tract dynamia related drugs cisapride by syndrome.But, these treatment by Chinese herbs poor effect, and the western medicine time is long, expense is expensive, and the abdominal cramps of instantaneity, borborygmus or diarrhoea easily occur, and easily causes Liver and kidney organ injury.
Irritable bowel syndrome is treated varied clinically, and the cause of disease is complicated, and symptom is more and easily repeatedly, can not rely on merely specific Drug therapy.Now conventional clinically Chinese patent medicine is mainly based on Shenlingbaizhu pills.We's card is caused by insufficiency of the spleen leading to overabundance of dampness.Weakness of the spleen and stomach, fortune of receiving is weak, therefore indigestion; Indigestion, clear QI being mixed up with turbid QI, therefore see increased borborygmus and diarrhea; Burnt in humidity hysteresis, mechanism of qi is hindered, and sees that breast gastral cavity painful abdominal mass is vexed; Dysfunction of the spleen in transportation, then insufficiency of generating and transforming QI and blood; Limbs skin loses in moistening foster, therefore myasthenia of limbs, emaciated physique, shallow complexion; Light red tongue, tongue is greasy in vain, and deficient pulse is slow is all resembling of insufficiency of the spleen leading to overabundance of dampness.Control and should strengthen the spleen and stomach, hold concurrently with eliminating dampness by diuresis antidiarrheal.In side, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the eliminating dampness by diuresis of Poria replenishing QI to invigorate the spleen are monarch.Compatibility Rhizoma Dioscoreae, Semen Nelumbinis principal drug assistance are with invigorating the spleen and benefiting QI, and holding concurrently can antidiarrheal; And help the Rhizoma Atractylodis Macrocephalae, Poria with spleen invigorating eliminating dampness by diuresis with Semen Lablab Album, Semen Coicis, be ministerial drug.More to be amusing stomach function regulating with Fructus Amomi, promoting qi circulation, resolving food retention is adjuvant drug.Radix Platycodonis lung qi dispersing promoting the circulation of QI, regulating fluid apssage, again can medicine carrying up, building up the spleen to supplement the lung; Radix Glycyrrhizae (parched) spleen invigorating and in, coordinating the actions of various ingredients in a prescription, altogether for assistant makes.Take a broad view of full side, invigorating middle warmer gas, eliminating dampness by diuresis is turbid, and circulation of qi promoting is stagnant, and make the strong fortune of temper, damp must be gone, then all diseases are from removing.Be used for treating the inappetence caused by weakness of the spleen and stomach, diarrhea, lean body mass, distension and fullness in the abdomen, mental weariness, the diseases such as myasthenia of limbs in clinical.In addition, through clinical discovery, SHENLING BAISHU SAN can also in treatment chronic diarrhea, chronic gastritis, gastrointestinal dysfunction, chronic colitis, chronic nephritis, infantile malnutrition, chemicotherapy causes gastrointestinal tract toxicity, central serous chorioretinopathy, the diseases such as chronic otitis media.Shenlingbaizhu pills treatment still treats the inappetence caused with weakness of the spleen and stomach, diarrhea, lean body mass, distension and fullness in the abdomen, and mental weariness is main, separately because treatment intestinal stress syndrome effect not be also too obvious.
Western medicine and medical practitioners coordinates live triple capsule for treating with cisapride, mainly treats the acute and chronic diarrhea because alteration of intestinal flora causes, constipation, also can be used for treating medium-sized acute diarrhea, and chronic diarrhea and dyspepsia, abdominal distention are main; Western medicine is mainly with regulating intestinal canal dysbacteriosis.And long-time use easily causes abdominal cramps, borborygmus or diarrhoea that instantaneity easily occurs, easily causes Liver and kidney organ injury.
Summary of the invention
The object of the invention is to overcome above-mentioned technical problem and provide a kind of
For achieving the above object, the present invention adopts following technical scheme:
Treating intestinal stress the Chinese medicine composition of syndrome, comprises following component by weight: Radix Astragali 3-5 weight portion, Rhizoma Atractylodis Macrocephalae 8-10 weight portion, Radix Saposhnikoviae 3-5 weight portion, Radix Paeoniae Alba 8-10 weight portion, Radix Bupleuri 3-5 weight portion, Fructus Aurantii 3-5 weight portion, Rhizoma Corydalis 3-5 weight portion, Fructus Mume 1-2 weight portion, Radix Ophiopogonis 3-5 weight portion, Radix Salviae Miltiorrhizae 3-5 weight portion, Fructus Amomi Rotundus 1-2 weight portion, Pericarpium Citri Reticulatae Viride 1-2 weight portion, Poria 1-2 weight portion, Rhizoma Zingiberis 1-2 weight portion, Radix Glycyrrhizae 1-2 weight portion.
Above-mentioned treatment intestinal stress the preparation method of Chinese medicine composition of syndrome, comprises the following steps:
(1) take each medicine by prescription, get Fructus Mume, Fructus Amomi Rotundus, ginger powder be broken into coarse powder, add the water of 5-6 times of weight portion, soak 2-3 hour, distillating extracting oil, makes clathrate, and medicinal residues are for subsequent use;
(2) get Radix Salviae Miltiorrhizae, Radix Ophiopogonis according to the percolation under fluid extract and extractum item, use 75% ethanol as solvent, flood after 4 hours, slowly percolation, collection is filtered liquid, recovery ethanol, filtration, filtrate and medicinal residues for subsequent use;
(3) by step 1, step 2 medicinal residues and the Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Bupleuri, Fructus Aurantii, Rhizoma Corydalis, Pericarpium Citri Reticulatae Viride, Poria, Radix Glycyrrhizae, add 6-8 times of deal water, decoct twice, first time 2 hours, second time 1 hour; Merge decoction liquor, filter, filtrate and step 2 filtrate merge, and are concentrated into appropriate, add 2-3 times of ethanol, stir evenly, leave standstill 36 hours, filter, decompression filtrate recycling ethanol adds water in right amount, leaves standstill, and filters, adds the volatile oil in step 1 and clathrate, adjustment total amount, to 1000ml, stirs evenly, and leaves standstill, and filters, fill, sterilizing, after the assay was approved, subpackage, 100ml/ bottle, to obtain final product.
This preparation for treating intestinal stress syndrome curative effect high, short treating period, cure rate are high, the general patient course for the treatment of (10 days) Be very effective is obvious, and most of patients 2-3 the course for the treatment of can fully recover.
This preparation process thereof is studied, and makes a thorough investigation of medicine different qualities, adopts different processing methods, reasonable combination, the comprehensive therapeutic effect of the various compositions of the former medicine of abundant maintenance, makes medicine directly act on pathological changes local, fast onset therapeutical effect, any toxic and side effects, mouthfeel is good, and patient easily accepts.
Etiology and pathogenesis: this disease is that diseases caused by exogenous pathogenic factor ailment said due to cold or exposure is air-cooled, invasion and attack with in, or cold stagnant resistance knot gastral cavilty, causes stagnation of liver-QI with deficiency of the spleen, the liver failing to maintain the normal flow of QI, functional activity of QI being not smooth, disorder of emotion, incoordination between the spleen and stomach, with the passing of time can involve kidney yang; Clinical treatment primary disease is to nurse one's health strengthening vital QI to eliminate pathogenic factors, effect except cold syndrome of the stomach gas, invigorating the spleen and benefiting QI, dispersing the stagnated live-QI to relieve the stagnation of QI.
Medicine pharmacology:
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promotes the production of body fluid and nourishes blood, the stagnant arthralgia aggravated by cold of row, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, interior-heat is quenched one's thirst, blood deficiency dull yellowish colored skin, hemiplegia, and arthralgia pain is numb, and carbuncle difficulty is burst, and bursts for a long time and does not hold back; " Bencao Jingshu ": " the real table of function, person does not use pathogenic factor in the exterior; Can help gas, QI excess person does not use; Can interiorly fill in, tonifying for the deficiency, chest and diaphragm is gas-tight asks, the intestines and stomach has stagnant person not use; Energy YANG invigorating, overabundance of YANG leading to deficiency of YIN person avoids it; Part of the body cavity above the diaphragm housing the heart and lungs intenseness of heat, part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels deficiency and coldness person avoids it; The many anger of patient, disharmony in liver-QI person do not take; Variola blood system heat is notably forbidden.”
Rhizoma Atractylodis Macrocephalae (parched): bitter, sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement." medicineization justice ": all pent-up stagnation of QIs, feeling of distension and oppression gathers, and shouts to breathe heavily to be jammed, and has a stomachache by fire, the many pus of carbuncle, and black and thin popularity implementation is swollen, and all compatibility and incompatibility of drugs is used.
Radix Saposhnikoviae: acrid, sweet, warm.Return bladder, liver, spleen channel.Inducing diaphoresis to dispel wind, removing dampness to relieve pain, only stem.For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus." Bencao Jingshu ": all sick blood deficiency convulsions are anxious, headache is not because of in wind and cold, and diarrhea with loose stool not affection of cold is wet, and two constipation are puckery, and infantile spleen deficiency is sent out and jerked, the intermittent infantile convulsion chronic infantile convulsion due to dysfunction of the spleen, and gas lift is felt sick, and fire rises coughs, and night sweat due to yin deficiency, the diseases such as spontaneous perspiration due to yang insufficiency, method is avoided together.
The Radix Paeoniae Alba: bitter in the mouth, acid, be slightly cold.Return liver, spleen channel.Nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, suppressing liver-YANG.For blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, has a headache dizzy; [attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using." Bencao Jingshu ": " all invasion by pathogenic cold stomachache, invasion by pathogenic cold is let out, cold type of pain in abdomen, feels that the cold card that waits avoids it in the intestines and stomach." " property of medicine opinion ": " control pathogen of the lung gas, Fu Zhong Xu pain, vim and vigour are gathered, and logical a surname's internal organs gather around gas, control evil pain deteriorated blood, and disease bone heat time main, strong the five internal organs, the kidney invigorating gas, controls trusted subordinate's heavily fortified point swollen, and married woman's blood closes obstructed, and repercussive blood can lose pus.”
Radix Bupleuri: bitter, is slightly cold.Return liver, gallbladder, lung meridian.Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia; Uterine prolapse, proctoptosis; " herbal classic ": " stagnation of QI in main trusted subordinate's the intestines and stomach, diet gathers, and cold and heat pathogen, pushes away Chen Zhixin." " not Lu ": ", all expectorant accumulation of heats be real, evil inverse in the heart except dysphoria with smothery sensation under the typhoid fever heart, five hide between faint breath, large intestine stops amassing, watery distension, and arthralgia chiefly caused by damp pathogen contracture.Also can do to bathe soup."
Fructus Aurantii: bitter, pungent, sour, temperature.Return spleen, stomach warp.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Visceroptosis." Japan hanako materia medica ": spleen benefiting and stimulating the appetite, adjust the five internal organs, the therapeutic method to keep the adverse QI flowing downwards, preventing or arresting vomiting is inverse, expectorant.Control regurgitation, cholera dysentery, helps digestion, and broken crux mass beside the umbilicus, five types of dysphagia, except wind improving eyesight and lung qi edema, sharp intestine and small intestine, skin is itched.Swollen can the processing of hemorrhoid is pressed." Kaibao Bencao ": main air is itched paralysis, easing joint movement, consumptive disease is coughed, and back of the body arm is bored and listless, loosely stays knot, chest and diaphragm expectorant stagnant, and relieve oedema or abdominal distension through diuresis or purgation, full, the large hemorrhoidal hamorrhage of relieving distension, peace stomach, only wind bitterly.
Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, obstruction of qi in the chest and cardialgia, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling " Kaibao Bencao ", warm in nature, acrid in the mouth is bitter, enters the heart, spleen, liver, lung, is the quality goods of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, is especially world-famous for effect of pain relieving.Li Shizhen (1518-1593 A.D.) concludes Rhizoma Corydalis in Compendium of Material Medica " invigorate blood circulation, regulate the flow of vital energy, pain relieving, diuresis " four large effects, and praises highly Rhizoma Corydalis " can the stagnation of QI in promoting the circulation of blood, stasis in gas, therefore specially control upper and lower all pains all over the body ".。Modern pharmacological research proves through zoopery, and corydaline, Tetrahydropalmatine have analgesic activity, and Tetrahydropalmatine analgesia index is higher.Tetrahydropalmatine can suppress cerebral cortex and infracortical electrical activity, especially comparatively responsive with motor cortex.The Experimental Gastric Ucler that 13-Methylpalmatine can protect rat to produce because of hungry or injection cortisone and reserpine etc., reduces gastric secretion, reduces gastric acid and pepsic amount.
Fructus Mume: sour, puckery is flat.Return liver, spleen, lung, large intestine channel.Astringe the lung, astringing intestine to stop diarrhea, promotes the production of body fluid, relieving colic caused by ascaris.For chronic cough of deficiency lung, chronic dysentery laxation, deficiency-heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache." Bencao Jingshu ": Fructus Mume, namely the Fructus Mume of the present is also, the sourest." warp " is said: heat impairing vital QI, and evil visitor is in the heart, then gas superinverse and stuffy sensation with restlessness, the heart is uneasy for it.Fructus Mume sour in the mouth, can hold back superficial heat, air-breathing can return unit, therefore the main therapeutic method to keep the adverse QI flowing downwards, heat extraction stuffy sensation with restlessness and feeling at ease also.Dysentery person, large intestine collapse is also; Good saliva xerostomia person, hyperactivity of deficient fire, deficiency of body fluid is also; Acid can hold back asthenic fire, change body fluid, solid intestinal take off, so lead also.Its main limb pain, hemiplegia meciless person, covers because dampness is dipped in meridians, then muscle arteries and veins relaxes vertical, or pain is meciless; Liver governing tendons, sour in taste acting on the liver and nourishing muscle and tendon, liver obtain support, then solid skeleton and pliable tendons, machine-operated tonneau and front card removes.
Radix Ophiopogonis: sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, and Radix Ophiopogonis is classified as the top grade of nourishing YIN and moistening the lung by dryness of the intestine constipation Shennong's Herbal, says its " clothes are made light of one's life by commiting suicide for a long time, old not hungry "." herbal lease making " claims Radix Ophiopogonis, and " sweet, micro-hardship, is slightly cold.Lung moistening clears away heart-fire, purge heat and promote the production of body fluid, the preventing or arresting vomiting that reduces phlegm, control row water of coughing "." Records of Tradition Chinese and Western Medicine in Combination " says it: " can enter stomach with nourishing the stomach liquid, stimulating appetite, spleen is loose is skillful in lung, Dingchuan relieve coughing to help more to enter spleen." traditional Chinese medical science thinks; Radix Ophiopogonis sweet in the mouth, micro-hardship, cold nature, returns stomach, lung, heart channel; have nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the effect of the relieving restlessness that clears away heart-fire, for dryness of the lung dry cough, the disease such as deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, Tianjin wound are thirsty, interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.Modern pharmacological research also shows, Radix Ophiopogonis mainly containing dwarf lilyturf glycosides, steroidal saponin, alkaloid, sitosterol, glucose, aminoacid, vitamin etc., has resisting fatigue, scavenging free radicals, raising cellular immune function and hypoglycemic effect.In addition, there are calmness, hypnosis Radix Ophiopogonis, resist myocardial ischemia, the effect such as arrhythmia, antitumor, especially to enhancement senior health and fitness, there is many-sided effect.
In addition, also having Radix Ophiopogonis and promote that islet cell function recovers, increases hepatic glycogen, falls hypoglycemic effect, is the staple in sugared friendly prescription.Radix Ophiopogonis can for tea-drinking.Get appropriate Radix Ophiopogonis, boiled water soak, every day many clothes several times, effectively can alleviate the thirsty symptom of xerostomia.Part of diabetes mellitus patient deficiency of both QI and YIN, when therefore drinking water Radix Ophiopogonis, some Radix Codonopsis of can arranging in pairs or groups, more can play the effect of QI invigorating.
Radix Salviae Miltiorrhizae: bitter, is slightly cold.GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, clear away heart-fire relieving restlessness, removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, wrist abdomen hypochondriac pain ， lumps in the chest and abdomen, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, skin infection swells and ache; " herbal classic ": trusted subordinate's pathogen, borborygmus are faint, and as leaked water, cold and heat gather, and broken disease, except abdominal mass, stops stuffy sensation with restlessness, QI invigorating." not Lu ": nourish blood, remove trusted subordinate's obstinate disease stagnation of QI, stiffness along the spinal column foot numbness, exorcising stays heat.The sharp people of clothes of a specified duration." Japan hanako materia medica ": sedate of reposing, tonneau GUAN-pulse.Control cold and hot labor, arthralgia, extremity are unsuccessful; Evacuation of pus pain relieving, granulation promoting is put on flesh; Broken stagnated blood, mends new hemopoietic; Peaceful tire, fall stillborn fetus; Under hemostasis metrorrhagia and leukorrhagia, adjust married woman's passages through which vital energy circulates irregular, blood evil thought is tired of; Malignant boil scabies, wart is gone to live in the household of one's in-laws on getting married toxic swelling, erysipelas; Headache, acute conjunctivitis, hot temperature is mad vexed.
Fructus Amomi Rotundus: pungent, temperature.Return lung, spleen, stomach warp.Removing dampness circulation of qi promoting, warming middle-JIAO to arrest vomiting, appetite-stimulating indigestion-relieving.For turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia from the beginning of, uncomfortable in chest not hungry, cold-damp vomiting, chest and abdomen swelling and pain, food stagnation does not disappear." Bencao Jingshu ": Fructus Amomi Rotundus, pungently can break stagnant, and perfume (or spice) can enter spleen, warm can dispelling cold and eliminating dampness, therefore in main warming middle-JIAO and cold visitor, Jiao, cardiac and abdominal pain, invasion by pathogenic cold are vomitted also.The mouth is the body opening or window of the spleen, and spleen man has stagnant, then the stasis of blood and be heat, therefore send out halitosis, intestinal stasis relieving of being amusing, then implication is not smelly.Pungent loose temperature row, therefore the therapeutic method to keep the adverse QI flowing downwards.Burnt in cold visitor, diet does not disappear, and gas is because closing stagnant then cholera.Again all cold air loose, disappear alcoholism person, also dampness breaks the merit of stagnant, circulation of qi promoting spleen benefiting and stimulating the appetite also.Produce Jianning person in Fujian, gas virtue is strong, class Fructus Amomi Rotundus, and kind cold scattering gas, treats gastric abscess, regulating the function of middle-JIAO.Produce Yunnan, expensive, Nan Yuezhe, gas is violent and turbid, and custom exhales Fructus Tsaoko, and person is also, kind broken communicable subtropical diseases, and rapid digestion of food is eaten, and feeling of distension and oppression and pain are made in the stagnation of all dyspepsia." book on Chinese herbal medicine is looked for the truth ": Semen Alpiniae Katsumadai, hot perfume (or spice) falls apart, and merit is similar to Semen Myristicae, but this hot dampness is except cold, and property has concurrently puckery, not in the majority like Semen Myristicae adstringency, can stop the prolapse of the rectum endlessly also.Merit is identical with Fructus Tsaoko again, but this stops by wind and cold visitor on appetite, and disease sees careful pain, hot floating loose like Fructus Tsaoko, specially controls communicable subtropical diseases algid malaria also.Therefore all damp-stagnancy becomes sick, and see that gastral cavilty is done to ache, clothes the most effective.If make hot and suffocating interior one-tenth, and the dry person of deficiency of YIN blood, clothes for avoid ear greatly.
Pericarpium Citri Reticulatae Viride: bitter, pungent, temperature.Return liver, gallbladder, stomach warp.Soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For distending pain in the chest and hypochondrium, hernia pain, nodules of the breast, acute mastitis, abdominal pain due to retention of food, wrist abdominal distention and pain." Bencao Tujing ": the main stagnation of QI, lower food, removing mass knot and diaphragm gas.Compendium of Material Medica: control chest and diaphragm QI rising in reverse order, hypochondriac pain, lower abdomen hernia, disappear swelling of the breast, soothing the liver gallbladder, eliminating the pathogens from the lung gas.
Poria: sweet, light is flat.GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia." book on Chinese herbal medicine is just ": can dry by sharp key, sharp key is happy Fructus Alpiniae Oxyphyllae then, leads turbid promoting the production of body fluid; Dry, dry spleen of relieving oedema or abdominal distension through diuresis or purgation, invigorating middle warmer stomach invigorating; Eradicates infantile convulsion, thick intestines and internal organs of the body, control expectorant originally, help falling of medicine.Have with its taste micro-sweet, therefore say YANG invigorating.But mend few benefit.Compendium of Material Medica: Poria abnormal smells from the patient is light and ooze, and its property is up, born fluid, loosing the interspaces of skin and muscles, grows water source and declines, diuresis, therefore Zhang Jiegu calls its genus sun, floats and rises, saying its property also; Dong Yuan calls it for the YIN aspect of YANG, fall and under, Yan Qigong is also.
Rhizoma Zingiberis: pungent, heat.Return spleen, stomach, kidney, the heart, lung meridian.Warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, cold fluid-retention is breathed with cough.Compendium of Material Medica: Rhizoma Zingiberis, can draw that blood medicine enters blood system, gas medicine enters edema caused by disorder of QI.Can go again to dislike and support newly, have the meaning of Yin grows while yang is generating, therefore blood deficiency person use it.Ordinary person's haematemesis, epistaxis, hematochezia, YIN without YANG person, also should with it, and be treating hot natured symptoms(pseudomorph)with hot natured medicine, the method for contrary treatment also." herbal classic ": main fullness in the chest cough with dyspnea, warming middle-JIAO, hemostasis, perspire, by rheumatism numbness, the out-of-the-way dysentery of intestinal, survivor is especially good.
Radix Glycyrrhizae: sweet, flat.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong; Should not with Sargassum, Radix Euphorbiae Pekinensis, Radix Knoxiae, Radix Kansui, Flos Genkwa with using.
Detailed description of the invention
Below, in conjunction with example, substantive distinguishing features of the present invention and advantage are further described, but the present invention is not limited to listed embodiment.
Embodiment 1
A kind of intestinal for the treatment of stress the Chinese medicine composition of syndrome, it is characterized in that, comprise following component by weight: the Radix Astragali 3 weight portion, the Rhizoma Atractylodis Macrocephalae 8 weight portion, Radix Saposhnikoviae 3 weight portion, the Radix Paeoniae Alba 8 weight portion, Radix Bupleuri 3 weight portion, Fructus Aurantii 3 weight portion, Rhizoma Corydalis 3 weight portion, Fructus Mume 1 weight portion, Radix Ophiopogonis 3 weight portion, Radix Salviae Miltiorrhizae 3 weight portion, Fructus Amomi Rotundus 1 weight portion, Pericarpium Citri Reticulatae Viride 1 weight portion, Poria 1 weight portion, Rhizoma Zingiberis 1 weight portion, Radix Glycyrrhizae 1 weight portion.
Above-mentioned treatment intestinal stress the preparation method of Chinese medicine composition of syndrome, comprises the following steps:
(1) take each medicine by prescription, get Fructus Mume, Fructus Amomi Rotundus, ginger powder be broken into coarse powder, add the water of 5 times of weight portions, soak 2 hours, distillating extracting oil, makes clathrate, and medicinal residues are for subsequent use;
(2) get Radix Salviae Miltiorrhizae, Radix Ophiopogonis according to the percolation under fluid extract and extractum item, use 75% ethanol as solvent, flood after 4 hours, slowly percolation, collection is filtered liquid, recovery ethanol, filtration, filtrate and medicinal residues for subsequent use;
(3) by step 1, step 2 medicinal residues and the Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Bupleuri, Fructus Aurantii, Rhizoma Corydalis, Pericarpium Citri Reticulatae Viride, Poria, Radix Glycyrrhizae, add 6 times of deal water, decoct twice, first time 2 hours, second time 1 hour; Merge decoction liquor, filter, filtrate and step 2 filtrate merge, and are concentrated into appropriate, add 2 times of ethanol, stir evenly, leave standstill 36 hours, filter, decompression filtrate recycling ethanol adds water in right amount, leaves standstill, and filters, adds the volatile oil in step 1 and clathrate, adjustment total amount, to 1000ml, stirs evenly, and leaves standstill, and filters, fill, sterilizing, after the assay was approved, subpackage, 100ml/ bottle, to obtain final product.
Usage and dosage: oral, one time one bottle, one day 2-3 time;
Attention: anemia of pregnant woman is forbidden, period in a medicine forbidding spicy food.
Embodiment 2
A kind of intestinal for the treatment of stress the Chinese medicine composition of syndrome, it is characterized in that, comprise following component by weight: the Radix Astragali 5 weight portion, the Rhizoma Atractylodis Macrocephalae 10 weight portion, Radix Saposhnikoviae 5 weight portion, the Radix Paeoniae Alba 10 weight portion, Radix Bupleuri 5 weight portion, Fructus Aurantii 5 weight portion, Rhizoma Corydalis 5 weight portion, Fructus Mume 2 weight portion, Radix Ophiopogonis 5 weight portion, Radix Salviae Miltiorrhizae 5 weight portion, Fructus Amomi Rotundus 2 weight portion, Pericarpium Citri Reticulatae Viride 2 weight portion, Poria 2 weight portion, Rhizoma Zingiberis 2 weight portion, Radix Glycyrrhizae 2 weight portion.
Above-mentioned treatment intestinal stress the preparation method of Chinese medicine composition of syndrome, comprises the following steps:
(1) take each medicine by prescription, get Fructus Mume, Fructus Amomi Rotundus, ginger powder be broken into coarse powder, add the water of 6 times of weight portions, soak 3 hours, distillating extracting oil, makes clathrate, and medicinal residues are for subsequent use;
(2) get Radix Salviae Miltiorrhizae, Radix Ophiopogonis according to the percolation under fluid extract and extractum item, use 75% ethanol as solvent, flood after 4 hours, slowly percolation, collection is filtered liquid, recovery ethanol, filtration, filtrate and medicinal residues for subsequent use;
(3) by step 1, step 2 medicinal residues and the Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Bupleuri, Fructus Aurantii, Rhizoma Corydalis, Pericarpium Citri Reticulatae Viride, Poria, Radix Glycyrrhizae, add 8 times of deal water, decoct twice, first time 2 hours, second time 1 hour; Merge decoction liquor, filter, filtrate and step 2 filtrate merge, and are concentrated into appropriate, add 3 times of ethanol, stir evenly, leave standstill 36 hours, filter, decompression filtrate recycling ethanol adds water in right amount, leaves standstill, and filters, adds the volatile oil in step 1 and clathrate, adjustment total amount, to 1000ml, stirs evenly, and leaves standstill, and filters, fill, sterilizing, after the assay was approved, subpackage, 100ml/ bottle, to obtain final product.
Usage and dosage: oral, one time one bottle, one day 2-3 time;
Attention: anemia of pregnant woman is forbidden, period in a medicine forbidding spicy food.
My seminar of institute, according to theory of Chinese medical science, in conjunction with pharmacological research in modern age.The basis being used in YUPINGFENG SAN creates this preparation, with medicine composition prescriptions such as the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Radix Saposhnikoviae, Radix Bupleuri, Fructus Aurantii, Rhizoma Corydalis, Fructus Mume, Radix Ophiopogonis, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Radix Glycyrrhizaes.There is strengthening vital QI to eliminate pathogenic factors significantly, effect except cold syndrome of the stomach gas, invigorating the spleen and benefiting QI, dispersing the stagnated live-QI to relieve the stagnation of QI.
We derive from YUPINGFENG SAN and add Radix Paeoniae Alba plus-minus and form, we's card for deficiency of defensive qi weak, can not caused by consolidating superficial resistance.Exterior deficiency interspaces of skin and muscles being loose, then easily by ailment said due to cold or exposure is attacked, defend empty lose solid, battalion's the moon can not in keep, body fluid leaks, then spontaneous perspiration aversion to wind.Control suitable QI invigorating righting, strengthening superficial resistance to stop perspiration.The sweet temperature of the Radix Astragali in side, interior can the gas of spleen reinforcing lung greatly, outward can strengthening superficial resistance to stop perspiration, be monarch drug.Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, helping the Radix Astragali to strengthen the power of benefiting QI for strengthening the superficies, is ministerial drug.Two medicines share, and make the prosperous table of gas real, then antiperspirant does not leak, heresy also not easily in invade.Help and walk to show and dispelling wind evil with Radix Saposhnikoviae, conjunction stilbene, art then righting are main, hold concurrently with eliminating evil.Wherein the Radix Astragali obtains Radix Saposhnikoviae, then consolidating superficial resistance and do not stay heresy; Radix Saposhnikoviae obtains the Radix Astragali, then eliminating evil and just do not hinder, both mutual restraint between two drugs and the mutual-assistance.For exterior deficiency spontaneous perspiration, or body void is easy to flu person, has the merit of benefiting QI for strengthening the superficies, strengthening vital QI to eliminate pathogenic factors with it.Effect of strengthening vital QI to eliminate pathogenic factors, " dispeling cold " is played at this preparation.The effects such as Radix Paeoniae Alba blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating, we reuse the effect of dysentery stomachache.The effect of the dispersing the stagnated live-QI to relieve the stagnation of QI of Radix Bupleuri, Fructus Aurantii regulating the flow of QI to ease the stomach, the stagnant relieving distension of row; Pericarpium Citri Reticulatae Viride is soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant; Both share the breast side of body stagnation of QI, and distension pain, accumulation of food in the stomach and intes tine due to indigestion, the effect of stopping in phlegm retention, Rhizoma Corydalis promoting the circulation of QI to relieve pain, Fructus Mume is astringed the lung, astringing intestine to stop diarrhea, the effect of promoting the production of body fluid.Rhizoma Zingiberis, Fructus Amomi Rotundus are used for relieving dyspepsia removing food stagnancy, and warming spleen and stomach for dispelling cold, acts on the merit of cold syndrome of the stomach.Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, Poria spleen invigorating eliminating dampness by diuresis, Radix Glycyrrhizae and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.
The YUPINGFENG SAN present pharmaceutical research monarch drug Radix Astragali has by weakening attack factor the effect reducing gastric acid secretion, suppress pepsin activity, reduce serum gastrin, thus has antiulcer action; Ministerial drug Rhizoma Atractylodis Macrocephalae water extract and acetone extract have significant protective effect to gastric ulcer, particularly acetone extract energy gastric acid secretion inhibiting, reduce gastric acid and pepsic discharge capacity, have protective effect to gastric mucosa; The Rhizoma Atractylodis Macrocephalae has Biphasic Regulation to intestinal tube function, when intestinal tube by Ach affect be in excitatory state time, the Rhizoma Atractylodis Macrocephalae is inhibitory action; When intestinal tube is in inhibitory state by adrenal gland's effect, the Rhizoma Atractylodis Macrocephalae then excitement, thus make gastrointestinal motility recover normally; Adjuvant drug Radix Saposhnikoviae has spasmolysis to intestinal smooth.This preparation is at YUPINGFENG SAN basis plus-minus, and producing a kind of special for treating intestinal stress the medicine of syndrome, stress syndrome Be very effective for intestinal, obtains the accreditation of extensive patients.
My institute applies this preparation clinically, on syndrome, stress obtain promising result at treatment intestinal.Choose now 100 routine clinical patients and carry out statistical analysis:
1. clinical data
The analysis of cases of this group is all intestinal stress syndrome patients.Treat 300 routine patients, three groups are divided into according to patient profiles's difference, treatment group 100g oral preparation (oral 4-6 grain, 2-3 time on the one), matched group one group of oral Shenlingbaizhu pills (an oral 6g, 2 times on the one), contrast two groups of oral cisaprides and live triple capsule (oral, live triple capsule 2-4 grain, 2 times on the one; Oral, cisapride 5 ~ 10mg/ time, 3 times/day.); Wherein in 300 routine patients, female 186 example, man 114 example, max age 42 years old, minimal ages 19 years old, 31.2 years old mean age; The course of disease is the longest 2 years, the shortest 15 days.
Treatment intestinal stress compare with Shenlingbaizhu pills, live triple capsule by this preparation of syndrome:
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (2)
1. one kind treat intestinal stress the Chinese medicine composition of syndrome, it is characterized in that, comprise following component by weight: Radix Astragali 3-5 weight portion, Rhizoma Atractylodis Macrocephalae 8-10 weight portion, Radix Saposhnikoviae 3-5 weight portion, Radix Paeoniae Alba 8-10 weight portion, Radix Bupleuri 3-5 weight portion, Fructus Aurantii 3-5 weight portion, Rhizoma Corydalis 3-5 weight portion, Fructus Mume 1-2 weight portion, Radix Ophiopogonis 3-5 weight portion, Radix Salviae Miltiorrhizae 3-5 weight portion, Fructus Amomi Rotundus 1-2 weight portion, Pericarpium Citri Reticulatae Viride 1-2 weight portion, Poria 1-2 weight portion, Rhizoma Zingiberis 1-2 weight portion, Radix Glycyrrhizae 1-2 weight portion.
2. treating intestinal described in claim 1 stress the preparation method of Chinese medicine composition of syndrome, it is characterized in that, comprises the following steps:
(1) take each medicine by prescription, get Fructus Mume, Fructus Amomi Rotundus, ginger powder be broken into coarse powder, add the water of 5-6 times of weight portion, soak 2-3 hour, distillating extracting oil, makes clathrate, and medicinal residues are for subsequent use;
(2) get Radix Salviae Miltiorrhizae, Radix Ophiopogonis according to the percolation under fluid extract and extractum item, use 75% ethanol as solvent, flood after 4 hours, slowly percolation, collection is filtered liquid, recovery ethanol, filtration, filtrate and medicinal residues for subsequent use;
(3) by step 1, step 2 medicinal residues and the Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Bupleuri, Fructus Aurantii, Rhizoma Corydalis, Pericarpium Citri Reticulatae Viride, Poria, Radix Glycyrrhizae, add 6-8 times of deal water, decoct twice, first time 2 hours, second time 1 hour; Merge decoction liquor, filter, filtrate and step 2 filtrate merge, and are concentrated into appropriate, add 2-3 times of ethanol, stir evenly, leave standstill 36 hours, filter, decompression filtrate recycling ethanol adds water in right amount, leaves standstill, and filters, adds the volatile oil in step 1 and clathrate, adjustment total amount, to 1000ml, stirs evenly, and leaves standstill, and filters, fill, sterilizing, after the assay was approved, subpackage, 100ml/ bottle, to obtain final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610056107.7A CN105561273A (en) | 2016-01-28 | 2016-01-28 | Traditional Chinese medicine composition for treating intestinal tract stress syndromes and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610056107.7A CN105561273A (en) | 2016-01-28 | 2016-01-28 | Traditional Chinese medicine composition for treating intestinal tract stress syndromes and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105561273A true CN105561273A (en) | 2016-05-11 |
Family
ID=55872274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610056107.7A Pending CN105561273A (en) | 2016-01-28 | 2016-01-28 | Traditional Chinese medicine composition for treating intestinal tract stress syndromes and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105561273A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728202A (en) * | 2016-12-27 | 2017-05-31 | 广东轻工职业技术学院 | One kind treats person in middle and old age's chronic diarrhea traditional Chinese compound medicine and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463417A (en) * | 2013-09-30 | 2013-12-25 | 丰建君 | Traditional Chinese medicine used for treating irritable bowel syndrome |
| CN104069459A (en) * | 2014-07-03 | 2014-10-01 | 张新红 | Traditional Chinese medicine composition for treating irritable bowel syndrome and preparation method thereof |
-
2016
- 2016-01-28 CN CN201610056107.7A patent/CN105561273A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463417A (en) * | 2013-09-30 | 2013-12-25 | 丰建君 | Traditional Chinese medicine used for treating irritable bowel syndrome |
| CN104069459A (en) * | 2014-07-03 | 2014-10-01 | 张新红 | Traditional Chinese medicine composition for treating irritable bowel syndrome and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 张容德: "中医辨证治疗肠道易激综合征38例", 《吉林中医药》 * |
| 施捷: "中药治疗肠易激综合征28例疗效分析", 《天津中医》 * |
| 闫领全等: "抑激调肠汤治疗肠易激综合征40例", 《四川中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728202A (en) * | 2016-12-27 | 2017-05-31 | 广东轻工职业技术学院 | One kind treats person in middle and old age's chronic diarrhea traditional Chinese compound medicine and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103623388B (en) | A kind of Chinese medicine preparation for the treatment of chronic gastritis and preparation method thereof | |
| CN103432475B (en) | Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof | |
| CN104225441A (en) | Traditional Chinese medicine composition for treating stomach trouble and preparation method of granules and capsules of traditional Chinese medicine composition | |
| CN104383132B (en) | Traditional Chinese medicine preparation used for treating gastric ulcer and preparation method | |
| CN101537156A (en) | Chinese herbal medicine composite capable of curing stomach illness and duodenal ulcer disease | |
| CN104189783A (en) | Traditional Chinese medicine for treating oral ulcer | |
| CN104001045A (en) | Drug for treating dog pneumonia and preparation method thereof | |
| CN111588828A (en) | Chinese medicinal preparation for treating new coronavirus and viral diseases, and its preparation method | |
| CN104547313B (en) | It is a kind of to treat lung cancer, breast cancer, the medicine of lymph cancer and preparation method | |
| CN104826012A (en) | Traditional Chinese medicine preparation for pituitary tumor surgery postoperative nursing and preparation method thereof | |
| CN104027786A (en) | Traditional Chinese medicine decoction for treating pulmonary edema | |
| CN105561273A (en) | Traditional Chinese medicine composition for treating intestinal tract stress syndromes and preparation method thereof | |
| CN103816366B (en) | A kind of medicine treating oral ulcer | |
| CN106177392A (en) | A kind of decoction medicine treating exogenous high fever and preparation method thereof | |
| CN104998074A (en) | Traditional Chinese medicine for treating gastropathy and preparation method thereof | |
| CN104888178A (en) | Infantile diarrhea treatment traditional Chinese medicine | |
| CN104353043A (en) | Traditional Chinese medicine composition for treating dawn diarrhea and preparation method thereof | |
| CN104324314A (en) | Pharmaceutical composition for treating gastropathy | |
| CN104147573A (en) | Heat clearing and toxin removing preparation for treating wind-induced headache | |
| CN104013761A (en) | Traditional Chinese medicine irrigating solution for treating ascaris intestinal obstruction | |
| CN105709005A (en) | Breast rehabilitation promoting pill | |
| CN106109895A (en) | A kind of Chinese medicine composition treating phlegm stagnation fire type chronic pharyngitis and method | |
| CN104721786A (en) | Traditional Chinese medicine preparation for treating intrahepatic cholestasis of pregnancy and preparation method of traditional Chinese medicine preparation | |
| CN105056064A (en) | Traditional Chinese medicine for treating allergic rhinitis | |
| CN104623471A (en) | Traditional Chinese medicine emulsion for treating stomach and duodenal ulcer and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160511 |
|
| RJ01 | Rejection of invention patent application after publication |