CN105560663A - Traditional Chinese medicinal composition for treating diseases caused by exogenous seasonal pathogenic factors and preparation method thereof - Google Patents
Traditional Chinese medicinal composition for treating diseases caused by exogenous seasonal pathogenic factors and preparation method thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/355—Lonicera (honeysuckle)
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention relates to a traditional Chinese medicinal composition for treating diseases caused by exogenous seasonal pathogenic factors and a preparation method thereof. The traditional Chinese medicinal composition is characterized by comprising the following bulk pharmaceutical chemicals by weight: 3-10 parts of patchouli, 2-12 parts of herba eupatorii, 5-12 parts of folium artemisiae argyi, 4-20 parts of honeysuckle, 4-20 parts of Acorus gramineus Soland., 3-30 parts of rhizoma nardostachyos, 2-12 parts of sandalwood, 5-20 parts of clove, 4-16 parts of mint, and 3-16 parts of schizonepeta ear. The invention also discloses a preparation method. The traditional Chinese medicinal composition has the effects of expelling pathogenic wind from the body surface, removing dampness to restore normal functioning of the stomach, promoting qi circulation to alleviate middle energizer, coursing the liver and regulating spleen.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method thereof and detection method, particularly a kind ofly treat Chinese medicine composition of diseases caused by exogenous pathogenic factor seasonal pathogen and preparation method thereof.
Background technology
Influenza is the acute febrile respiratory infectious disease caused by influenza virus, and through droplet transmission, clinical typical performance is projection fear of cold, high heat, headache, systemic pain, the weak and weary systemic toxicity profiles symptom such as weak, and respiratory symptom is lighter.Primary disease is often in self limiting, and the course of disease is generally 3 ~ 4 days.Infant, old people, have heart and lung diseases and other patients with chronic diseases or immunologic hypofunction person can Complicating Pneumonia In Patients, prognosis be poor.
The treatment of influenza uses antibiotic therapy usually, and effect is undesirable, and antibiotic usage is too much, can cause the dysbacteriosis of human body, and strengthens the drug resistance of antibacterial, larger to the side effect of people.
It is little that China's traditional medicine is of extensive knowledge and profound scholarship, Chinese medicine has side effect, and the feature that conditioning functions is outstanding, effectively can improve the problems such as influenza.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of diseases caused by exogenous pathogenic factor seasonal pathogen, another object of the present invention is to provide this Chinese medicine composition to obtain preparation method.
The present invention seeks to be achieved through the following technical solutions: the crude drug of this Chinese medicine composition and weight portion are: Herba Pogostemonis 3-10 part, Herba Eupatorii 2-12 part, Folium Artemisiae Argyi 5-12 part, Flos Lonicerae 4-20 part, Rhizoma Acori Graminei 4-20 part, Radix Et Rhizoma Nardostachyos 3-30 part, Lignum Santali Albi 2-12 part, Flos Caryophylli 5-20 part, Herba Menthae 4-16 part, Herba Schizonepetae 3-16 part.
The crude drug of this Chinese medicine composition and weight portion are preferably: Herba Pogostemonis 3-5 part, Herba Eupatorii 2-8 part, Folium Artemisiae Argyi 5-7 part, Flos Lonicerae 4-10 part, Rhizoma Acori Graminei 4-10 part, Radix Et Rhizoma Nardostachyos 3-5 part, Lignum Santali Albi 2-8 part, Flos Caryophylli 5-7 part, Herba Menthae 4-6 part, Herba Schizonepetae 3-7 part.
The crude drug of this Chinese medicine composition and weight portion can be: Herba Pogostemonis 3 parts, Herba Eupatorii 2 parts, Folium Artemisiae Argyi 5 parts, Flos Lonicerae 5 parts, Rhizoma Acori Graminei 5 parts, Radix Et Rhizoma Nardostachyos 3 parts, 2 parts, Lignum Santali Albi, Flos Caryophylli 5 parts, Herba Menthae 4 parts, Herba Schizonepetae 3 parts.
The crude drug of this Chinese medicine composition and weight portion can also be: Herba Pogostemonis 4 parts, Herba Eupatorii 6 parts, Folium Artemisiae Argyi 5 parts, Flos Lonicerae 8 parts, Rhizoma Acori Graminei 6 parts, Radix Et Rhizoma Nardostachyos 4 parts, 6 parts, Lignum Santali Albi, Flos Caryophylli 6 parts, Herba Menthae 5 parts, Herba Schizonepetae 4 parts.
The crude drug of this Chinese medicine composition and weight portion are preferably: Herba Pogostemonis 5 parts, Herba Eupatorii 7 parts, Folium Artemisiae Argyi 6 parts, Flos Lonicerae 10 parts, Rhizoma Acori Graminei 10 parts, Radix Et Rhizoma Nardostachyos 5 parts, 8 parts, Lignum Santali Albi, Flos Caryophylli 7 parts, Herba Menthae 6 parts, Herba Schizonepetae 6 parts.
Described Chinese medicine composition, adopt the known technology of this area to make various dosage form, its dosage form is the pharmaceutically acceptable exterior-applied formulations such as powder, granule, tablet, pill, powder.
The preparation method of described Chinese medicine composition is: Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos three taste pulverizing medicinal materials become granule; Whole medical material oven drying at low temperature is dry, and whole pulverizing medicinal materials, sieves, and mixing, subpackage, to obtain final product.
The preparation method of described Chinese medicine composition can also be: Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos three taste pulverizing medicinal materials become coarse granule; Whole medical material oven drying at low temperature is dry, and drying time is 2 hours, and Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos drying time are 3 hours; Whole pulverizing medicinal materials, sieves, and mixing, subpackage, to obtain final product.
The preparation method of described Chinese medicine composition is preferably: Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos three taste pulverizing medicinal materials become particle diameter to be the coarse granule of 0.3-0.5cm; Whole medical material 50 DEG C of bake dryings, drying time is 2 hours, and Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos drying time are 3 hours; Whole pulverizing medicinal materials, sieves, and carry out separating twice to the non-grinding medicinal materials sifted out, secondary sieves, and mixing, subpackage, to obtain final product.
The card that formula of the present invention cures mainly is caused by diseases caused by exogenous pathogenic factor seasonal pathogen, and Herba Pogostemonis induces sweat as monarch drug, Herba Eupatorii, Radix Et Rhizoma Nardostachyos removing dampness by means of aromatics, appetizing of being amusing, and delivering expelling summer-heat is ministerial drug, Rhizoma Acori Graminei waking up the patient from unconsciousness by dissipating phlegm; Herba Menthae has disperses wind heat, clearing throat; Herba Schizonepetae relieving the exterior syndrome by diaphoresis is adjuvant drug altogether, and Folium Artemisiae Argyi, Flos Lonicerae, Flos Caryophylli, Lignum Santali Albi energy the meridian dredging, for making medicine, play expelling pathogenic wind from the body surface, removing dampness to restore normal function of the stomach, promoting the circulation of QI to alleviate the stagnation in middle-JIAO, effect of smooth the liver and regulate the spleen altogether.
Chinese medicine composition of the present invention can expelling pathogenic wind from the body surface, removing dampness to restore normal function of the stomach, promoting the circulation of QI to alleviate the stagnation in middle-JIAO, smooth the liver and regulate the spleen, for diseases caused by exogenous pathogenic factor seasonal pathogen, turbid damp covers the caused headache of clear key, dizzy, nasal obstruction watery nasal discharge, fever with chills; Prevention influenza; Uncomfortable in chestly caused by stagnation of QI dampness not relax, epigastric distension and distress, nausea and vomiting, inappetence, turbid urine, the not well or laxativeness of stool viscous; Distending pain over the hypochondrium caused by depression of liver-QI, depressed or depressed, time for heaving a deep sigh; The diseases such as the caused insomnia such as qi depression to blood stasis.
The using method of Chinese medicine composition of the present invention is that Chinese medicine composition is put into utensil, as sachet etc., and body-worn.
Detailed description of the invention
Following examples for illustration of the present invention, but are not used for limiting the scope of the invention.
Embodiment 1
1, prescription:
Herba Pogostemonis 3 parts, Herba Eupatorii 2 parts, Folium Artemisiae Argyi 5 parts, Flos Lonicerae 5 parts, Rhizoma Acori Graminei 5 parts, Radix Et Rhizoma Nardostachyos 3 parts, 2 parts, Lignum Santali Albi, Flos Caryophylli 5 parts, Herba Menthae 4 parts, Herba Schizonepetae 3 parts.
2. method for making:
Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos three taste pulverizing medicinal materials become particle diameter to be the coarse granule of 0.3-0.5cm; Whole medical material 50 DEG C of bake dryings, drying time is 2 hours, and Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos drying time are 3 hours; Whole pulverizing medicinal materials, sieves, and carry out separating twice to the non-grinding medicinal materials sifted out, secondary sieves, and mixing, subpackage, to obtain final product.The medical material completed adopts gravimetric method carry out component and adopt double casing, and packaging nexine material selects cotton, guarantees fully distributing of medicinal ingredient, and outer employing packs.The support wearing made is on neck, is advisable in the position making the medicine in sachet be in TIANTU acupoint.Bedside can be placed in bed.
Embodiment 2
1, prescription:
Herba Pogostemonis 4 parts, Herba Eupatorii 6 parts, Folium Artemisiae Argyi 5 parts, Flos Lonicerae 8 parts, Rhizoma Acori Graminei 6 parts, Radix Et Rhizoma Nardostachyos 4 parts, 6 parts, Lignum Santali Albi, Flos Caryophylli 6 parts, Herba Menthae 5 parts, Herba Schizonepetae 4 parts.
2. method for making:
Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos three taste pulverizing medicinal materials become particle diameter to be the coarse granule of 0.3-0.5cm; Whole medical material 50 DEG C of bake dryings, drying time is 2 hours, and Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos drying time are 3 hours; Whole pulverizing medicinal materials, sieves, and carry out separating twice to the non-grinding medicinal materials sifted out, secondary sieves, and mixing, subpackage, to obtain final product.
Embodiment 3
1, prescription:
Herba Pogostemonis 5 parts, Herba Eupatorii 7 parts, Folium Artemisiae Argyi 6 parts, Flos Lonicerae 10 parts, Rhizoma Acori Graminei 10 parts, Radix Et Rhizoma Nardostachyos 5 parts, 8 parts, Lignum Santali Albi, Flos Caryophylli 7 parts, Herba Menthae 6 parts, Herba Schizonepetae 6 parts.
2. method for making:
Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos three taste pulverizing medicinal materials become particle diameter to be the coarse granule of 0.3-0.5cm; Whole medical material 50 DEG C of bake dryings, drying time is 2 hours, and Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos drying time are 3 hours; Whole pulverizing medicinal materials, sieves, and carry out separating twice to the non-grinding medicinal materials sifted out, secondary sieves, and mixing, subpackage, to obtain final product.The medical material completed adopts gravimetric method carry out component and adopt double casing, and packaging nexine material selects cotton, guarantees fully distributing of medicinal ingredient, and outer employing packs.The support wearing made is on neck, is advisable in the position making the medicine in sachet be in TIANTU acupoint.Bedside can be placed in bed.
Embodiment 4
1, prescription:
Herba Pogostemonis 3.5 parts, Herba Eupatorii 5 parts, Folium Artemisiae Argyi 5.5 parts, Flos Lonicerae 6 parts, Rhizoma Acori Graminei 4.5 parts, Radix Et Rhizoma Nardostachyos 5 parts, 2.5 parts, Lignum Santali Albi, Flos Caryophylli 5.5 parts, Herba Menthae 5 parts, Herba Schizonepetae 6 parts.
2. method for making:
Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos three taste pulverizing medicinal materials become particle diameter to be the coarse granule of 0.3-0.5cm; Whole medical material 50 DEG C of bake dryings, drying time is 2 hours, and Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos drying time are 3 hours; Whole pulverizing medicinal materials, sieves, and carry out separating twice to the non-grinding medicinal materials sifted out, secondary sieves, and mixing, subpackage, to obtain final product.
Embodiment 5 sachet is on the impact of influenza A virus A Lung Index of mice infected by Influenza virus
Get ICR mice 40, weight 13-16g, male and female half and half, be divided into 4 groups by body weight at random, often organize 10.1. Normal group; 2. model group; 3. sachet low dose group: 1 sachet (10g) is fixed on mouse cage top; 4. sachet high dose group: 2 sachets (20g) are fixed on mouse cage top.Each container 5 mices, after 5d, under ether light anaesthesia, to increase poison 3 influenza A virus allantoic fluid collunarium infecting mouses, every Mus 30 μ L, before experiment, water 12h is can't help in fasting, experiment mouse weights on the same day, de-cervical vertebra is put to death, and dissects, and observes pulmonary lesion, get lung and claim quality, calculate Lung Exponent value, lung index, more each group difference.In table 1
Table 1 sachet is on the impact (n=10) of influenza a virus infection mouse lung index
Note: compare with model group, * P < 0.05, * * P < 0.01
Experimental result shows: sachet high dose group and low dose group all can alleviate pneumonopathy caused by influenza A virus and become, and reduces Lung Exponent value, illustrates that sachet has influenza a virus infection and alleviate pneumonopathy change effect.
The protective effect of embodiment 6 sachet to the death of influenza A virus A/PR8/34 infecting mouse gets ICR mice 40, weight 13-16g, male and female half and half, is divided into 4 groups at random by body weight, often organizes 10.1. Normal group; 2. model group; 3. sachet low dose group: 1 sachet (10g) is fixed on mouse cage top; 4. sachet high dose group: 2 sachets (20g) are fixed on mouse cage top.Each container 5 mices.After 5d, administration same day under ether light anaesthesia, to increase the influenza A virus allantoic fluid of poison 3 times, record collunarium infected animal dead situation in 14d, calculated survival natural law, survival rate, compared group difference.The results are shown in Table 2.
Table 2 sachet is to the protective effect of influenza a virus infection dead mouse
Note: compare with model group, * P < 0.05, * * P < 0.01
Experimental result shows: it is caused dead that sachet high dose group and low dose group all can alleviate influenza A virus, and difference has statistical significance.
Claims (9)
1. treat the Chinese medicine composition of diseases caused by exogenous pathogenic factor seasonal pathogen for one kind, it is characterized in that crude drug and the weight portion of this Chinese medicine composition are: Herba Pogostemonis 3-10 part, Herba Eupatorii 2-12 part, Folium Artemisiae Argyi 5-12 part, Flos Lonicerae 4-20 part, Rhizoma Acori Graminei 4-20 part, Radix Et Rhizoma Nardostachyos 3-30 part, Lignum Santali Albi 2-12 part, Flos Caryophylli 5-20 part, Herba Menthae 4-16 part, Herba Schizonepetae 3-16 part.
2. Chinese medicine composition as claimed in claim 1, it is characterized in that crude drug and the weight portion of this Chinese medicine composition are: Herba Pogostemonis 3-5 part, Herba Eupatorii 2-8 part, Folium Artemisiae Argyi 5-7 part, Flos Lonicerae 4-10 part, Rhizoma Acori Graminei 4-10 part, Radix Et Rhizoma Nardostachyos 3-5 part, Lignum Santali Albi 2-8 part, Flos Caryophylli 5-7 part, Herba Menthae 4-6 part, Herba Schizonepetae 3-7 part.
3. Chinese medicine composition as claimed in claim 2, is characterized in that the crude drug of this Chinese medicine composition and weight portion are: Herba Pogostemonis 3 parts, Herba Eupatorii 2 parts, Folium Artemisiae Argyi 5 parts, Flos Lonicerae 5 parts, Rhizoma Acori Graminei 5 parts, Radix Et Rhizoma Nardostachyos 3 parts, 2 parts, Lignum Santali Albi, Flos Caryophylli 5 parts, Herba Menthae 4 parts, Herba Schizonepetae 3 parts.
4. Chinese medicine composition as claimed in claim 2, is characterized in that the crude drug of this Chinese medicine composition and weight portion are: Herba Pogostemonis 4 parts, Herba Eupatorii 6 parts, Folium Artemisiae Argyi 5 parts, Flos Lonicerae 8 parts, Rhizoma Acori Graminei 6 parts, Radix Et Rhizoma Nardostachyos 4 parts, 6 parts, Lignum Santali Albi, Flos Caryophylli 6 parts, Herba Menthae 5 parts, Herba Schizonepetae 4 parts.
5. Chinese medicine composition as claimed in claim 2, is characterized in that the crude drug of this Chinese medicine composition and weight portion are: Herba Pogostemonis 5 parts, Herba Eupatorii 7 parts, Folium Artemisiae Argyi 6 parts, Flos Lonicerae 10 parts, Rhizoma Acori Graminei 10 parts, Radix Et Rhizoma Nardostachyos 5 parts, 8 parts, Lignum Santali Albi, Flos Caryophylli 7 parts, Herba Menthae 6 parts, Herba Schizonepetae 6 parts.
6. the Chinese medicine composition as described in as arbitrary in claim 1 to 5, it is characterized in that, its dosage form is the external preparation such as powder, granule, tablet, pill, powder.
7. the preparation method of the Chinese medicine composition as described in as arbitrary in claim 1 to 5, is characterized in that the method is: Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos three taste pulverizing medicinal materials become granule; Whole medical material oven drying at low temperature is dry, and whole pulverizing medicinal materials, sieves, and mixing, subpackage, to obtain final product.
8. the preparation method of Chinese medicine composition as claimed in claim 7, is characterized in that the method is: Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos three taste pulverizing medicinal materials become coarse granule; Whole medical material oven drying at low temperature is dry, and drying time is 2 hours, and Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos drying time are 3 hours; Whole pulverizing medicinal materials, sieves, and mixing, subpackage, to obtain final product.
9. the preparation method of Chinese medicine composition as claimed in claim 7, is characterized in that the method is: Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos three taste pulverizing medicinal materials become particle diameter to be the coarse granule of 0.3-0.5cm; Whole medical material 50 DEG C of bake dryings, drying time is 2 hours, and Rhizoma Acori Graminei, Lignum Santali Albi, Radix Et Rhizoma Nardostachyos drying time are 3 hours; Whole pulverizing medicinal materials, sieves, and carry out separating twice to the non-grinding medicinal materials sifted out, secondary sieves, and mixing, subpackage, to obtain final product.
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| CN111481608A (en) * | 2020-03-20 | 2020-08-04 | 江苏上本健康科技有限公司 | Epidemic prevention sachet and medicinal powder thereof |
| CN112717115A (en) * | 2021-02-03 | 2021-04-30 | 杭州世子合德生物科技有限公司 | Chinese herbal medicine medicament and preparation method thereof |
| CN113491751A (en) * | 2020-04-02 | 2021-10-12 | 常州高新技术产业开发区三维工业技术研究所有限公司 | A medicated core for preventing influenza, Chinese medicinal composition, sachet, medicated bath bag, foot bath bag, and preparation method thereof |
| CN115607642A (en) * | 2022-06-13 | 2023-01-17 | 上海市第八人民医院 | Traditional Chinese medicine composition and sachet assisting in bacteriostasis or antivirus |
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Application publication date: 20160511 |