CN105560165A - Calamina gel and preparation method thereof - Google Patents
Calamina gel and preparation method thereof Download PDFInfo
- Publication number
- CN105560165A CN105560165A CN201510835578.3A CN201510835578A CN105560165A CN 105560165 A CN105560165 A CN 105560165A CN 201510835578 A CN201510835578 A CN 201510835578A CN 105560165 A CN105560165 A CN 105560165A
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- Prior art keywords
- calamina
- gel
- preparation
- zinc oxide
- carbomer
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Abstract
The invention relates to the technical field of pharmaceutical preparation, in particular to a Calamina gel and a preparation method thereof. The Calamina gel comprises the components: 15-20 g of Calamina, 5-7 g of zinc oxide, 40-50 mL of glycerol, 0.5-1 g of Gummi Tragacanthae, 1.2-1.5 g of carbomer, 5-7 g of triethanolamine, and 100 mL of purified water. The Calamina gel prepared by changing the form and modifying a formulation ratio can disperse evenly and has good release effect; when stored at normal temperature, the Calamina gel remains in its original shape and is free of drying, layering and caking; when spread, the Calamina gel is free of sand sensation and convenient to use.
Description
Technical field
The present invention relates to technical field of medicine preparation, be specifically related to a kind of Calamina gel and preparation method thereof.
Background technology
Calamina is carbonate mineral, and main component is basic zinc carbonate, after high-temperature process, be converted into zinc oxide.Zinc oxide is astringency, to skin have antibacterial, convergence is moistened, the effect of protection, the treatment disease such as eczema, skin pruritus, determined curative effect.Common dosage forms is lotion, owing to being suspensoid, placing and there will be precipitation, need before use to shake up.In use cause and use inconvenience.
Summary of the invention
The present invention is intended to for the problems referred to above, proposes a kind of Calamina gel and preparation method thereof.
Technical program of the present invention lies in:
A kind of Calamina gel, its composition is:
Calamina 15-20g,
Zinc oxide 5-7g,
Glycerol 40-50mL,
Tragakanta 0.5-1g,
Carbomer 1.2-1.5g,
Triethanolamine 5-7g,
Purified water 100mL.
The preparation method of Calamina gel, comprises following steps:
(1) get carbomer 1.2g, add 100ml purified water, place 24h, make it abundant evenly swelling, be translucent shape;
(2) get tragakanta 1g, use glycerol moistening, get Calamina 15g, zinc oxide 5g and mix, then add glycerol, mix homogeneously;
(3) Calamina of above-mentioned mix homogeneously, zinc oxide and glycerite are added in carbomer gel substrate, are ground to evenly, add triethanolamine adjust ph to 9-11, place and make gel, with homogenizer rapid stirring evenly.
Calamina in described step (2) was the Calamina of 120 mesh sieves.
Technique effect of the present invention is:
The present invention is by changing dosage form, and improve the Calamina gel that prescription proportioning is prepared into, dispersion of medicine, release is effective; Maintain the original state during normal temperature storage, not dry, not stratified, do not lump; Without grittiness during painting exhibition, easy to use.
Detailed description of the invention
A kind of Calamina gel, its composition is:
Calamina 15-20g,
Zinc oxide 5-7g,
Glycerol 40-50mL,
Tragakanta 0.5-1g,
Carbomer 1.2-1.5g,
Triethanolamine 5-7g,
Purified water 100mL.
The preparation method of Calamina gel, comprises following steps:
(1) get carbomer 1.2g, add 100ml purified water, place 24h, make it abundant evenly swelling, be translucent shape;
(2) get tragakanta 1g, use glycerol moistening, got the Calamina 15g of 120 mesh sieves, zinc oxide 5g and mix, then add glycerol, mix homogeneously;
(3) Calamina of above-mentioned mix homogeneously, zinc oxide and glycerite are added in carbomer gel substrate, are ground to evenly, add triethanolamine adjust ph to 9-11, place and make gel, with homogenizer rapid stirring evenly.
Claims (3)
1. a Calamina gel, is characterized in that: its composition is:
Calamina 15-20g,
Zinc oxide 5-7g,
Glycerol 40-50mL,
Tragakanta 0.5-1g,
Carbomer 1.2-1.5g,
Triethanolamine 5-7g,
Purified water 100mL.
2. a preparation method for Calamina gel as claimed in claim 1, is characterized in that: comprise following steps:
(1) get carbomer 1.2g, add 100ml purified water, place 24h, make it abundant evenly swelling, be translucent shape;
(2) get tragakanta 1g, use glycerol moistening, get Calamina 15g, zinc oxide 5g and mix, then add glycerol, mix homogeneously;
(3) Calamina of above-mentioned mix homogeneously, zinc oxide and glycerite are added in carbomer gel substrate, are ground to evenly, add triethanolamine adjust ph to 9-11, place and make gel, with homogenizer rapid stirring evenly.
3. the preparation method of Calamina gel according to claim 2, is characterized in that: the Calamina in described step (2) was the Calamina of 120 mesh sieves.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510835578.3A CN105560165A (en) | 2015-11-26 | 2015-11-26 | Calamina gel and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510835578.3A CN105560165A (en) | 2015-11-26 | 2015-11-26 | Calamina gel and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105560165A true CN105560165A (en) | 2016-05-11 |
Family
ID=55871193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510835578.3A Pending CN105560165A (en) | 2015-11-26 | 2015-11-26 | Calamina gel and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105560165A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111135115A (en) * | 2018-11-06 | 2020-05-12 | 上海家化联合股份有限公司 | Composition containing calamine |
-
2015
- 2015-11-26 CN CN201510835578.3A patent/CN105560165A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111135115A (en) * | 2018-11-06 | 2020-05-12 | 上海家化联合股份有限公司 | Composition containing calamine |
| CN111135115B (en) * | 2018-11-06 | 2023-10-17 | 上海家化联合股份有限公司 | Calamine-containing composition |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160511 |
|
| WD01 | Invention patent application deemed withdrawn after publication |