CN105536036A - New medical material - Google Patents
New medical material Download PDFInfo
- Publication number
- CN105536036A CN105536036A CN201511015297.XA CN201511015297A CN105536036A CN 105536036 A CN105536036 A CN 105536036A CN 201511015297 A CN201511015297 A CN 201511015297A CN 105536036 A CN105536036 A CN 105536036A
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- CN
- China
- Prior art keywords
- parts
- powder
- aloe
- chitosan
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/0005—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0015—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a new medical material. The new material is prepared from the following raw materials in parts by mass: 80-150 parts of butyl cyanoacrylate, 0.01-0.1 part of hydroquinone, 5-24 parts of aloe nano micro-powder, 20-55 parts of soybean protein powder, 10-44 parts of chitosan, 1-5 parts of acetic acid and 8-18 parts of polyvinyl alcohol. According to the new medical material disclosed by the invention, the impact resistance is enhanced by the aloe nano micro-powder, and the product degradability is improved by the natural plant extraction essence and ingredients; the bacterium inhibiting activity of the product is enhanced by the chitosan component; and the product has the advantages of moderate curing speed, high bonding strength, low heat release in bonding, good toughness of a bonding film and little skin irritation, and realizes a high-strength quick bonding effect on various wounds and operative incisions while avoiding scars after curing.
Description
Technical field
The present invention relates to a kind of medical new material, belong to medical assistant product technical field.
Background technology
Medical glue is the emerging curable product replacing suture needle, and the main component of medical glue is a-cyano group acrylic acid ester, and it is the fastest at the polymerization speed of bio-tissue.Under the effect of medical glue anion in wound surface blood and tissue fluid; energy rapid polymerization film-forming is also inlayed closely with wound surface; the apposition of wound can be kept securely; and glued membrane can stop blood cell, platelet is passed through; under thrombin and fibrinogenic combined effect; the thin vessels of wound closure fracture can effectively stop blooding, and glued membrane will be organized and antibacterial isolation simultaneously, also have the effect of infection and protection wound surface.Ether chain in polymer also has analgesic effect, therefore medical adhesive glassware for drinking water have sticky and, hemostasis, pain relieving, antiinflammatory, protect the comprehensively effect such as wound, Promotive union.
Compared with traditional sewing, medical adhesive water has the following advantages: 1, quick-acting haemostatic powder, and sticky and process does not have misery, does not need anesthesia.2, wound linearly heals, and without foreign bodies such as suture needle sutures to the stimulation of skin, reduce the generation of inflammation, the cicatrix of formation is very little, has good cosmetic result.3, need not take out stitches, greatly shorten Waiting time, save expense of seeking medical advice.4, in inguinal hernia Liechtenstein Hernioplasty, applied chemistry medical adhesive binds the respond well of fixing sticking patch and wound surface hemostasis, do not increase Postoperative recurrent rate, operating time can be saved and alleviate postoperative pain, also can reduce the generation of postoperative chronic pain and local hematoma.
Existing medical glue exists: impact resistance is poor, degradation speed is slow, the shortcoming of cohesion insufficient strength.
Summary of the invention
The object of this invention is to provide a kind of medical new material.
Technical scheme of the present invention is as follows: a kind of medical new material, is prepared by the raw material of following mass parts: Tisuacryl 80 ~ 150 parts, hydroquinone 0.01 ~ 0.1 part, Aloe nano powder 5 ~ 24 parts, soybean protein powder 20 ~ 55 parts, chitosan 10 ~ 44 parts, acetic acid 1 ~ 5 part, polyvinyl alcohol 8 ~ 18 parts.
The preparation method of described Aloe nano powder is: get fresh aloe, is dried to moisture 10 ~ 20%, is crushed to particle diameter 300 ~ 500nm.
The preparation method that the present invention states medical new material is: the chitosan solution of deionized water configuration concentration 20 ~ 40%, add the deionized water of chitosan solution volume 2 ~ 4 times again, be heated to 40 ~ 60 DEG C, add Tisuacryl, polyvinyl alcohol, hydroquinone, soybean protein powder, Aloe nano powder successively, mixing and stirring, adjustment is solid to be contained to production requirement.
Medical new material of the present invention, by adding Aloe nano powder, improves its impact resistance, and natural plant extract elite and composition make product more easily degrade; Chitosan component adds the Antibacterial activity of product, and products solidifying speed of the present invention is moderate, and bonding strength is high, time bonding, heat release is low, adhering film good toughness, little to skin irritation, to various wound, operative incision, there is the effect of high strength quick-binding, without cicatrix after solidification.
Detailed description of the invention
Be described in further details the present invention below by embodiment, these embodiments are only used for the present invention is described, do not limit the scope of the invention.
Embodiment 1 one kinds of medical new materials, are prepared by the raw material of following mass parts: Tisuacryl 150 parts, hydroquinone 0.1 part, Aloe nano powder 8 parts, soybean protein powder 55 parts, chitosan 44 parts, acetic acid 5 parts, polyvinyl alcohol 16 parts; Preparation method is:
(1) get fresh aloe, be dried to moisture 15%, be crushed to particle diameter 300 ~ 500nm;
(2) each raw material is got by proportioning, the chitosan solution of deionized water configuration concentration 30%, add the deionized water of chitosan solution volume 4 times again, be heated to 50 DEG C, add Tisuacryl, polyvinyl alcohol, hydroquinone, soybean protein powder, Aloe nano powder mixing and stirring successively, adjustment is solid to be contained to 25%.
Embodiment 2 one kinds of medical new materials, are prepared by the raw material of following mass parts: Tisuacryl 100 parts, hydroquinone 0.051 part, Aloe nano powder 24 parts, soybean protein powder 20 parts, chitosan 10 parts, acetic acid 1 part, polyvinyl alcohol 8 parts; Preparation method is:
(1) get fresh aloe, be dried to moisture 20%, be crushed to particle diameter 300 ~ 500nm;
(2) each raw material is got by proportioning, the chitosan solution of deionized water configuration concentration 40%, add the deionized water of chitosan solution volume 3 times again, be heated to 60 DEG C, add Tisuacryl, polyvinyl alcohol, hydroquinone, soybean protein powder, Aloe nano powder mixing and stirring successively, adjustment is solid to be contained to 30%.
Embodiment 3 one kinds of medical new materials, are prepared by the raw material of following mass parts: Tisuacryl 80 parts, hydroquinone 0.01 part, Aloe nano powder 22 parts, soybean protein powder 35 parts, chitosan 30 parts, acetic acid 3 parts, polyvinyl alcohol 18 parts; Preparation method is:
(1) get fresh aloe, be dried to moisture 10%, be crushed to particle diameter 300 ~ 500nm;
(2) each raw material is got by proportioning, the chitosan solution of deionized water configuration concentration 20%, add the deionized water of chitosan solution volume 2 times again, be heated to 40 DEG C, add Tisuacryl, polyvinyl alcohol, hydroquinone, soybean protein powder, Aloe nano powder mixing and stirring successively, adjustment is solid to be contained to 20%.
Claims (3)
1. a medical new material, is characterized in that: prepared by the raw material of following mass parts: Tisuacryl 80 ~ 150 parts, hydroquinone 0.01 ~ 0.1 part, Aloe nano powder 5 ~ 24 parts, soybean protein powder 20 ~ 55 parts, chitosan 10 ~ 44 parts, acetic acid 1 ~ 5 part, polyvinyl alcohol 8 ~ 18 parts.
2. medical new material according to claim 1, is characterized in that: the preparation method of described Aloe nano powder is: get fresh aloe, is dried to moisture 10 ~ 20%, is crushed to particle diameter 300 ~ 500nm.
3. medical new material according to claim 1, it is characterized in that: its preparation method is: the chitosan solution of deionized water configuration concentration 20 ~ 40%, add the deionized water of chitosan solution volume 2 ~ 4 times again, be heated to 40 ~ 60 DEG C, add Tisuacryl, polyvinyl alcohol, hydroquinone, soybean protein powder, Aloe nano powder mixing and stirring successively, adjustment is solid to be contained to production requirement.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511015297.XA CN105536036A (en) | 2015-12-31 | 2015-12-31 | New medical material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511015297.XA CN105536036A (en) | 2015-12-31 | 2015-12-31 | New medical material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105536036A true CN105536036A (en) | 2016-05-04 |
Family
ID=55815907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201511015297.XA Pending CN105536036A (en) | 2015-12-31 | 2015-12-31 | New medical material |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105536036A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177354A (en) * | 2016-08-04 | 2016-12-07 | 陈广圣 | A kind of draft antibacterial |
| CN106267327A (en) * | 2016-08-30 | 2017-01-04 | 裴寿益 | A kind of glue for sewing up a wound and preparation method thereof |
| CN106381077A (en) * | 2016-08-30 | 2017-02-08 | 裴寿益 | High-molecular eco-friendly silica gel adhesive and preparation method thereof |
| CN107802882A (en) * | 2017-11-07 | 2018-03-16 | 黄建文 | A kind of medical new material |
| CN109266227A (en) * | 2018-09-28 | 2019-01-25 | 桐城市双港森科塑料厂 | A kind of medical new material |
-
2015
- 2015-12-31 CN CN201511015297.XA patent/CN105536036A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177354A (en) * | 2016-08-04 | 2016-12-07 | 陈广圣 | A kind of draft antibacterial |
| CN106267327A (en) * | 2016-08-30 | 2017-01-04 | 裴寿益 | A kind of glue for sewing up a wound and preparation method thereof |
| CN106381077A (en) * | 2016-08-30 | 2017-02-08 | 裴寿益 | High-molecular eco-friendly silica gel adhesive and preparation method thereof |
| CN107802882A (en) * | 2017-11-07 | 2018-03-16 | 黄建文 | A kind of medical new material |
| CN109266227A (en) * | 2018-09-28 | 2019-01-25 | 桐城市双港森科塑料厂 | A kind of medical new material |
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Legal Events
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| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160504 |