CN105535845A - Composition medicine for treating schizophrenia - Google Patents

Composition medicine for treating schizophrenia Download PDF

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CN105535845A
CN105535845A CN201610032004.7A CN201610032004A CN105535845A CN 105535845 A CN105535845 A CN 105535845A CN 201610032004 A CN201610032004 A CN 201610032004A CN 105535845 A CN105535845 A CN 105535845A
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radix
medicine
phlegm
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庞群
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/808—Scrophularia (figwort)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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Abstract

The invention relates to a composition medicine for treating schizophrenia, belongs to the technical field of medicines, and aims to solve the problem of medicines for treating schizophrenia. 'Wind', 'phlegm', 'deficiency' and 'fire' are taken as the etiology and pathogenesis, the medicine combination which comprises the following components and has the effects of tonifying qi and activating blood, opening apertures and dredging collaterals, clearing heat and dissolving phlegm, expelling wind and removing toxin as well as removing stasis and dredging collaterals is taken as a treatment medicine: 20 parts of turtle shells, 12 parts of salvia miltiorrhiza, 10 parts of unprepared ochre, 12 parts of unprepared rehmannia glutinosa, 10 parts of radix scrophulariae, 10 parts of scutellaria baicalensis, 10 parts of radix curcumae, 15 parts of astragalus membranaceus, 9 parts of leach, 13 parts of polygala tenuifolia, 10 parts of ligusticum wallichii, 10 parts of earth worms, 10 parts of bile arisaema, 12 parts of poria cocos, 10 parts of frankincense, 10 parts of rhizoma acori graminei and 8 parts of liquorice. The composition medicine is based on correct medical theories and is remarkable in practical treatment effect.

Description

One treats schizoid combination medicine
Technical field
The present invention relates to the schizoid medicine for the treatment of, belong to medicine technology field.
Background technology
Schizophrenia is the not bright major psychosis of one group of cause of disease, many person between twenty and fifty slow or subacute onset, often show as the different syndrome of symptom clinically, relate to the inharmonious of many-sided obstacles such as sensory perception, thinking, emotion and behavior and ergasia.The general Clear consciousness of patient, intelligence is normal, but some patients there will be the infringement of cognitive function in lysis.The course of disease is generally delayed, and in recurrent exerbation, increases the weight of or worsens, and decline and mental handicap finally appear in some patients, but some patients can keep recovery from illness or the state that is almost recovered after treatment.
The clinical syndrome that schizophrenia is made up of one group of syndrome, it is multifactorial disease.Although at present still not bery clear and definite to the understanding of its cause of disease, the effect that the susceptible quality of individual mind and the undesirable element of outside social environment develop the generation of disease know together by everybody.Be susceptible quality or outside undesirable element all can cause disease generation by inherent biological factor combined effect, factor of its morbidity of different patient may with outbalance in a certain respect.1 neurobiology factor; 2 genetics factors; Large sample crowd genetic epidemiology investigation display, the prevalence in patients' relatives is higher than population several times, and blood relationship is nearer, and prevalence is higher.Molecule genetics research has pointed out the tumor susceptibility gene position relevant with schizophrenia.Generally believe at present, schizophrenia may be polygenic inheritance, and morbidity is caused by the superposition of some genes.3 social psychology factors; The social psychology factors such as bad life events, economic situation, premorbid personality, may serve and bring out and facilitation in schizophrenic onset.The schizoid cause of disease still end is illustrated completely, and more confirmable influence factors, do not have clear and definite cause effect relation to disease at present.The viewpoint of comparatively generally acknowledging at present is that susceptible quality and outside undesirable element cause the generation of disease by inherent biological factor combined effect.
Schizophrenia clinical manifestation.Schizoid clinical symptoms complexity is various, and can relate to the aspects such as sensory perception, thinking, emotion, volitional behavior and cognitive function, between individuality, symptom is widely different, even if same patient also may show different symptoms in different phase or stadium.(1) can there is multiple sensory perception obstacle in sensory perception obstacle schizophrenia, and the most outstanding sensory perception obstacle is hallucination, comprise auditory hallucination, photis, olfactory hallucination, gustatory hallucination and tactile hallucination etc., and auditory hallucination is the most common.(2) thought disturbance thought disturbance is schizoid core symptom, mainly comprises form of thinking obstacle and content of thought obstacle.(3) the apathy and emotional responses of affective disorder is inharmonious is the modal affective symptom of schizophrenic, and in addition, the affective symptom such as incoordination excitement, irritability, depression and anxiety are also more common.(4) hypobulia of will and behavior disorder most of patients even lacks, show as movable minimizing, peel off and stay alone, behavior is passive, lack due enthusiasm and initiative, working and learning interest is gone down, is indifferent to future, to clearly not intending in the future, some patient may have some plans and intend, but seldom performs.(5) cognitive dysfunction incidence rate of cognitive defect in schizophrenic is high, and cognitive dysfunction appears in about 85% patient, as information processing and selective attention, working memory, short term memory and the cognitive defect such as study, n-back test.
Summary of the invention
Analyze schizophrenia with Chinese medicine, make etiology and pathogenesis with " wind ", " expectorant ", " void ", " fire "." wind " in Chinese medicine namely because of the ferritic deficiency of YIN, seven emotions excessively, hypoimmunity, the invasion of bacterium heresy; " expectorant " namely ecchymosis, humidity hysteresis become expectorant, phlegm stagnating in meridian humorously; " void " is because nephrons is not solid, deficiency of both QI and blood hypoimmunity.Chinese traditional treatment schizophrenia, should take treatment with the Chinese medicine composition of inrigorating qi and promoting blood circulation, dredging collateral of having one's ideas straightened out, clearing away heat and eliminating phlegm, the toxin expelling that dispels the wind, disperse blood stasis and dredge collateral.
It is combine by each Chinese medicine quality part ratio below that one treats schizoid combination medicine: Carapax Trionycis 20 parts, Radix Salviae Miltiorrhizae 12 parts, Haematitum 10 parts, 12 parts, the Radix Rehmanniae, Radix Scrophulariae 10 parts, Radix Scutellariae 10 parts, Radix Curcumae 10 parts, the Radix Astragali 15 parts, Hirudo 9 parts, Radix Polygalae 13 parts, Rhizoma Chuanxiong 10 parts, Pheretima 10 parts, Arisaema Cum Bile 10 parts, 12 parts, Poria, Olibanum 10 parts, Rhizoma Acori Graminei 10 parts, 8 parts, Radix Glycyrrhizae.
Analyze a kind of property of medicine drug effect for the treatment of each Chinese medicine in schizoid combination medicine below one by one. effect of Carapax Trionycis and effect, nourishing YIN for suppressing the hyperactive YANG, tonification adjust in, reinforcing the kidney to strengthen the bone, cure mainly deficiency of kidney yin, hectic fever night sweat, hyperactivity of YANG due to deficiency of YIN, fires dizziness, consumption of YIN caused by febrile disease, stirring of wind due to deficiency of YIN, malaria with splenomegaly, mass in the abdomen, the breast side of body is had a pain, purplish or white patches on the skin abdominal mass is gathered, and menstruation is obstructed.Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, evacuation of pus, pain relieving.Control angina pectoris, menoxenia, dysmenorrhea, amenorrhea, metrorrhagia leukorrhagia ， mass in the abdomen, gathers, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.The Radix Rehmanniae has YIN nourishing and the production of body fluid promoting effect, and, interior-heat thirsty for Tianjin wound is quenched one's thirst.Effect of Radix Scrophulariae and effect: send out the diseases such as macule for join the army blood, thirsty crimson tongue, agitation, uneasy sleeping at night, unconsciousness or body of warm febrile disease.Radix Scutellariae is used as medicine with root, has that heat clearing and damp drying, removing heat from blood are antiabortive, detoxicating functions.Radix Curcumae promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood, promoting the function of the gallbladder to alleviate jaundice.The Radix Astragali has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely, his-and-hers watches excess pathogen Sheng, retention of dampness due to stagnation of QI, food stagnation are stagnated, carbuncle from the beginning of or after bursting the excess syndrome such as pyretic toxicity Shang Sheng and hyperactivity of YANG due to deficiency of YIN person have the Liao Dynasty's effect.Hirudo, popular name Hirudo, growth and breeding in the freshwater of inland, it is the medicinal aquatic animal of special type of Chinese tradition, the brewed rear traditional Chinese medical science of its dry products is used as medicine, have the effect such as treatment apoplexy, hypertension, the clear stasis of blood, amenorrhea, traumatic injury, new discovery Hirudo has specially good effect at control cardiovascular and cerebrovascular disease and anticancer aspect in recent years.The function that Radix Polygalae has Fructus Alpiniae Oxyphyllae of calming the nerves, eliminates the phlegm, subsides a swelling, the insomnia and dreamful sleep caused for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin.Rhizoma Chuanxiong acrid in the mouth, warm in nature, return liver, gallbladder, heart channel, gas perfume rises loose, has effect of blood-activating and qi-promoting, wind-expelling pain-stopping.Pheretima has heat clearing away arresting convulsion, dredging collateral, relievings asthma, effect of diuresis.Arisaema Cum Bile effect: removing heat-phlegm, dispelling wind and relieving convulsion, for phlegm-heat cough, cough up phlegm yellow thick, middle wind-phlegm fan, demented infantile convulsion.The primary efficacy of Poria is spleen invigorating mind calming, promoting diuresis to eliminate damp pathogen, and the traditional Chinese medical science is usually used in insufficiency of the spleen caused various diseases.The pain relieving of Olibanum blood-activating and qi-promoting, detumescence and promoting granulation.Rhizoma Acori Graminei, acrid in the mouth, hardship, slightly warm in nature; GUIXIN, liver, spleen channel, can waking up the patient from unconsciousness by dissipating phlegm, removing dampness circulation of qi promoting, dispel the wind sharp numbness, reducing swelling and alleviating pain, main calentura coma, syncope due to accumulation of phlegm, forgetful, tinnitus, deafness, abdominal distention, fasting dysentery, rheumatic arthralgia, traumatic injury, carbuncle scabies, refreshment of having one's ideas straightened out, cover clear key for expectorant, mind is murky.The invigorating middle warmer of Radix Glycyrrhizae QI invigorating, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, the mediation property of medicine.
The beneficial effect for the treatment of schizoid composition of medicine is: inventor analyzes a schizophrenia with Chinese medicine, makes etiology and pathogenesis with " wind ", " expectorant ", " void ", " fire "; By " wind " in Chinese medicine namely because of the ferritic deficiency of YIN, seven emotions excessively, hypoimmunity, the invasion of bacterium heresy; " expectorant " namely ecchymosis, humidity hysteresis become expectorant, phlegm stagnating in meridian humorously; " void ", because nephrons is not solid, deficiency of both QI and blood hypoimmunity, is taked to take treatment with the Chinese medicine composition of inrigorating qi and promoting blood circulation, dredging collateral of having one's ideas straightened out, clearing away heat and eliminating phlegm, the toxin expelling that dispels the wind, disperse blood stasis and dredge collateral, be have received obvious therapeutic effect.
Detailed description of the invention
Schizoid composition of medicine is treated to one below and make further implementation.
A kind of to treat medicine that schizoid composition of medicine is suitable for the dosage that a patient takes be combine by each Chinese medicine quality ratio below: Carapax Trionycis 20 grams, Radix Salviae Miltiorrhizae 12 grams, Haematitum 10 grams, 12 grams, the Radix Rehmanniae, Radix Scrophulariae 10 grams, Radix Scutellariae 10 grams, Radix Curcumae 10 grams, the Radix Astragali 15 grams, Hirudo 9 grams, Radix Polygalae 13 grams, Rhizoma Chuanxiong 10 grams, Pheretima 10 grams, Arisaema Cum Bile 10 grams, 12 grams, Poria, Olibanum 10 grams, Rhizoma Acori Graminei 10 grams, 8 grams, Radix Glycyrrhizae.
One treats schizoid composition of medicine using method: above-mentioned each Chinese medicine dosage proper amount of clear water is dipped into moistening rear decoction taking liquid half an hour and takes, within two days, take dose, a dosage can take effect, and serve on three dosage and receives more obvious therapeutic effect.

Claims (2)

1. treat a schizoid combination medicine, it is characterized in that combining by each Chinese medicine quality part ratio below: Carapax Trionycis 20 parts, Radix Salviae Miltiorrhizae 12 parts, Haematitum 10 parts, 12 parts, the Radix Rehmanniae, Radix Scrophulariae 10 parts, Radix Scutellariae 10 parts, Radix Curcumae 10 parts, the Radix Astragali 15 parts, Hirudo 9 parts, Radix Polygalae 13 parts, Rhizoma Chuanxiong 10 parts, Pheretima 10 parts, Arisaema Cum Bile 10 parts, 12 parts, Poria, Olibanum 10 parts, Rhizoma Acori Graminei 10 parts, 8 parts, Radix Glycyrrhizae.
2. one according to claim 1 treats schizoid combination medicine, and the medicine that it is characterized in that being suitable for the dosage that a patient takes combines by each Chinese medicine quality ratio below: Carapax Trionycis 20 grams, Radix Salviae Miltiorrhizae 12 grams, Haematitum 10 grams, 12 grams, the Radix Rehmanniae, Radix Scrophulariae 10 grams, Radix Scutellariae 10 grams, Radix Curcumae 10 grams, the Radix Astragali 15 grams, Hirudo 9 grams, Radix Polygalae 13 grams, Rhizoma Chuanxiong 10 grams, Pheretima 10 grams, Arisaema Cum Bile 10 grams, 12 grams, Poria, Olibanum 10 grams, Rhizoma Acori Graminei 10 grams, 8 grams, Radix Glycyrrhizae.
CN201610032004.7A 2016-01-19 2016-01-19 Composition medicine for treating schizophrenia Withdrawn CN105535845A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106310136A (en) * 2016-09-30 2017-01-11 李先强 Preparation method of pill with efficacy of calming liver, eliminating phlegm and sterilizing paranoid

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101934057A (en) * 2010-10-12 2011-01-05 姚春雨 Traditional Chinese medicine for treating schizophrenia

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101934057A (en) * 2010-10-12 2011-01-05 姚春雨 Traditional Chinese medicine for treating schizophrenia

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106310136A (en) * 2016-09-30 2017-01-11 李先强 Preparation method of pill with efficacy of calming liver, eliminating phlegm and sterilizing paranoid

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