CN106310136A - Preparation method of pill with efficacy of calming liver, eliminating phlegm and sterilizing paranoid - Google Patents
Preparation method of pill with efficacy of calming liver, eliminating phlegm and sterilizing paranoid Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/808—Scrophularia (figwort)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
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Abstract
The invention discloses a preparation method of a pill with the efficacy of calming liver, eliminating phlegm and sterilizing paranoid, belongs to the technical field of medicines and aims to solve the problem of treatment of schizophrenia. The preparation method is characterized in that the pill is prepared from the following traditional Chinese medicinal raw materials and preparation method: firstly, the traditional Chinese medicinal raw materials comprise the following raw materials in parts by mass: 12 parts of radix salviae miltiorrhizae, 30 parts of black soybean with the mass of 10g, 12 parts of dried radix rehmanniae, 10 parts of radix scrophulariae, 10 parts of radix achyranthis bidentatae, 10 parts of rhizoma acori graminei, 10 parts of radix curcumae, 15 parts of radix astragali seu hedysari, 9 parts of gypsum, 13 parts of radix polygalae, 10 parts of rhizoma chuanxiong, 10 parts of arisaema cum bile and 8 parts of liquorice root; secondly, all the traditional Chinese medicines are crushed into mixed medicinal powder; thirdly, the mixed medicinal powder and a proper amount of starch are uniformly matched, then are spread, and are subjected to die pressing, thus obtaining a medicinal pill.
Description
Technical field
The present invention relates to antipsychotic medicine, particularly to the medicine combined with plurality of Chinese, belong to medicine
Learn a skill field.
Background technology
Schizophrenia (schizophrenia) is a kind of common psychosis, estimates according to World Health Organization (WHO), whole world essence
The lifetime prevalence of god's Split disease is about 3.8 ‰-8.4 ‰, and the research of the U.S., lifetime prevalence is up to 13 ‰;China 1994
Year survey data, urban area prevalence 7.11 ‰, rural area 4.26 ‰.The schizophrenia cause of disease is complicated, and still end illustrates completely.Many
Onset, in person between twenty and fifty, shows as many-sided obstacle such as perception, thinking, emotion, volitional behavior, ergasia and surrounding and interior
The heart is experienced inharmonious, is divorced from reality.General unconscious obstacle and obvious disturbance of intelligence, can have attention, working memory, abstract think of
The aspect Cognitive function damagies such as peacekeeping information integration.The many delays of the course of disease, recurrent exerbation, some patients generation ergasia decline and
Social function defect in various degree.
Neural Biochemical Research shows, patient there are various neurotransmitters dysfunction, relates generally to dopamine, 5-hydroxyl color
Amine, glutamic acid.Central dopamine level increases, hyperfunctioning, and traditional antipsychotics is central nervous system's dopamine and is subject to
The blocker of body.Maincenter 5-hydroxy tryptamine horizontal abnormality, New antipsychotics is in addition to having antagonism to dopamine receptor, also
5-hydroxytryptamine receptor there is antagonism.Maincenter glutamate levels is low, and function is not enough.2. neuro anatomy and neuroimaging grind
Studying carefully display, there is shrinking of brain tissues in patient's temporal lobe, frontal lobe and limbic system, and the ventricles of the brain expand and ditch increases back up width.3. female pregnancy period virus
Infect, perinatal complication, the distress of childhood and physical disease, relevant with nervous system development defect, in schizophrenia
Disease morbidity has certain impact.The investigation display of large sample crowd's genetic epidemiology, the prevalence in patients' relatives is higher than general
Crowd's several times, blood relationship is the nearest, and prevalence is the highest.Molecule genetics research has pointed out the easy sensillary base relevant with schizophrenia
Because of position.At present it is believed that schizophrenia is probably polygenic inheritance, morbidity is caused by the superposition by some genes.
The schizoid cause of disease still end illustrates completely, more confirmable influence factors, the brightest to disease
True cause effect relation.The viewpoint the most relatively generally acknowledged is, susceptible quality and outside undesirable element are common by inherent biological factor
Act on and cause the generation of disease.Most patients belongs to chronic onset, and the enthusiasm of work and ability to work decline, Students ' Learning
Teaching, cold to people, become estranged with people, things is lost interest in external world, does not knows to care for household, life sluggishness, quick
Feel suspicious, personality change etc..Some patients can have sense of discomfort and the neurosis diseases such as insomnia, headache, dizziness, unable, emotional lability
Shape.Some cases can drastically onset, clinically show as unexpected excitement, impulsion, gibberish, conduct disorder, segment hallucination more
And vain hope.
Schizophrenia mainly shows as vain hope.Vain hope is a kind of pathologic distortion conviction, this conviction and objective thing
Reality, institute's education level, culture background etc. are inconsistent, the most absurd odd, but patient really believes firmly, it is impossible to persuaded,
Can not personal experience be corrected.Vain hope is one of modal symptom of schizophrenia, may occur in which various vain hope, part
Patient's vain hope is the most prominent.At the disease initial stage, patient may be half believing, half doubting, along with the state of an illness to some obvious irrational idea
Development, combines together with the conviction of morbid state, and oneself can not identify.
Some psychoactive drug substance (such as analeptic, ethanol etc.) and the use of medicine (such as hormone etc.), may result in psychosis
Shape occurs.Differential point: have the medication history determined, the time of occurrence medication of mental symptom is closely related.
Therapeutic Principle: 1. early find, early treatment;2. Drug therapy can alleviate overwhelming majority symptom, antipsychotic drug
Treatment should be used as the remedy measures of first-selection, and Drug therapy should be used as ingredient important in treatment;3. enough, foot is needed during treatment
The course for the treatment of, and actively carry out full course of disease treatment;4. treatment of schizophrenia is long-term treatment, medicament selection consider symptom, side reaction,
Individual tolerance, considers ability to shoulder economically and availability simultaneously;5. the dosage of medicine answers individuation, and with different treatments
Stage is adjusted;6. patient can face psychology and social problem, is a part for disease performance, is also psychological stress after being ill
Reaction, generally to carry out psychosocial intervention;7. family plays very important effect, family members to treatment, the rehabilitation of patient
It should be understood that disease knowledge, support patient treatment, help to select correct therapy approach;8. treatment of schizophrenia is to control for a long time
Treating, patient and family members must grasp self management's technical ability of disease, prevent recurrent exerbation, maintain the steady in a long-term of the state of an illness;⑨
Patient, family members, medical personnel set up good treatment alliance, jointly tackle disease.
Summary of the invention
With Chinese medicine analyze schizophrenia, with " expectorant ", " fiery ", " empty ", make etiology and pathogenesis, the most prosperous with liver-fire, the stagnation of QI
Disturb in fire-transformation, fluid transformed into phlegm by fire, expectorant heat, cover close thinking, " empty " in Chinese medicine i.e. because of the ferritic deficiency of YIN, seven emotions are excessive, immunity is low
Under, the invasion of bacterium heresy, humidity hysteresis become expectorant, phlegm stagnating in meridian;" empty " is because nephrons is not solid, deficiency of both QI and blood hypoimmunity.Chinese traditional treatment spirit
Split disease, with suppressing the hyperactive liver pathogenic fire purging, eliminating phlegm relieving palpitation, clearing away heat and eliminating phlegm, the Chinese medicine composition treatment having one's ideas straightened out of calming the nerves, and should be fabricated to pill, just
In taking treatment.
The manufacture method of the fixed mad ball of a kind of suppressing the hyperactive liver eliminating phlegm solves problem and adopts the technical scheme that by following each raw material of Chinese medicine
And manufacture method: raw material of Chinese medicine mass parts ratio one, used: Radix Salviae Miltiorrhizae 12 parts, 30 parts 10 parts of Semen sojae atricolor, 12 parts of the Radix Rehmanniae, Radix Scrophulariae 10 parts,
Radix Achyranthis Bidentatae 10 parts, Rhizoma Acori Graminei 10 parts, Radix Curcumae 10 parts, the Radix Astragali 15 parts, 9 parts of Gypsum Fibrosum, Radix Polygalae 13 parts, Rhizoma Chuanxiong 10 parts, Arisaema Cum Bile 10 parts, sweet
Grass 8 parts;Two, upper each Chinese medicine powder is broken into mixed powder;Three, mold pressing is shared after being coordinated with appropriate amount of starch by hybrid medicine powder uniformly
Become pill.
Analyze the property of medicine drug effect of each Chinese medicine in the manufacture method of the fixed mad ball of a kind of suppressing the hyperactive liver eliminating phlegm the most one by one.Salviamiltiorrhizabung energy
Blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, evacuation of pus, pain relieving;Control angina pectoris, menoxenia, dysmenorrhea, amenorrhea, metrorrhagia leukorrhagia, abdominal mass, accumulation, the stasis of blood
Hemoperitoneum pain, arthralgia, sleeplessness of palpitating with fear, malignant boil toxic swelling.Semen sojae atricolor has that heat clearing away of inducing sweat, the suppressing the hyperactive liver that nourishes blood, Bu Shen Zhuang be cloudy, qi-restoratives hair color it
Effect;Ancient times, Li Shizhen (1518-1593 A.D.) was said: " it is many that Semen sojae atricolor enters kidney merit, thus can harness the river, relieving distension, the therapeutic method to keep the adverse QI flowing downwards, control wind heat and promoting blood circulation and detoxication.", Semen sojae atricolor pair
People's nerve has physiotherapy function and fall electrostatic interaction.The Radix Rehmanniae has YIN nourishing and the production of body fluid promoting effect, and, interior-heat thirsty for Tianjin wound is quenched one's thirst.Profound
Effect of ginseng and effect: be used for warming join the army blood, thirsty crimson tongue, agitation, uneasy sleeping at night, unconsciousness or body of febrile disease and send out macule etc.
Disease.Rhizoma Acori Graminei is aroid, enters medicinal rhizome portion;Acrid in the mouth, warm in nature.Causing resuscitation with aromatic drugs, eliminates the phlegm by turbid, has stomach invigorating, profit
Urine, calm, analgesic activity;Often with treatment: dyspepsia, abdominal distention distending pain, intestinal toot the stagnation of QI, damp-warm diseases.The Radix Astragali has enhancing body
Immunologic function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and wide antibacterial action, to table excess pathogen Sheng, retention of dampness due to stagnation of QI,
Food stagnation is stagnated, carbuncle from the beginning of or after bursting the excess syndrome such as pyretic toxicity Shang Sheng and hyperactivity of YANG due to deficiency of YIN person have the Liao Dynasty's effect.Gypsum Fibrosum controls calentura high fever not
Moving back, vexed coma, delirium is gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire headache, toothache, hyperactivity of toxic heat.Radix Polygalae has
There are Fructus Alpiniae Oxyphyllae of calming the nerves, the function eliminated the phlegm, subside a swelling, the insomnia and dreamful sleep caused for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells, expectoration
Not well, sore swollen toxin.Radix Achyranthis Bidentatae Bu Shen Zhuang waist, dissipating blood stasis knot, subduing inflammation.Rhizoma Chuanxiong acrid in the mouth, warm in nature, return liver, gallbladder, heart channel, gas perfume (or spice) liter
Dissipate, there is effect of blood-activating and qi-promoting, wind-expelling pain-stopping.Arisaema Cum Bile function cures mainly: removing heat-phlegm, dispelling wind and relieving convulsion, for phlegm-heat cough,
Cough up phlegm yellow thick, middle wind-phlegm fan, demented infantile convulsion.Radix Glycyrrhizae QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, the mediation property of medicine.
The manufacture method beneficial effect of the invention of the fixed mad ball of a kind of suppressing the hyperactive liver eliminating phlegm is: the making of the fixed mad ball of a kind of suppressing the hyperactive liver eliminating phlegm
Method analyzes schizophrenia with Chinese medicine, with " expectorant ", " fiery ", " empty ", make etiology and pathogenesis, the most prosperous with liver-fire, stagnated QI transforming into fire,
Disturbing in fluid transformed into phlegm by fire, expectorant heat, illiteracy is closed thinking and is made pathology, further points out " empty " in Chinese medicine i.e. because of the ferritic deficiency of YIN, seven emotions mistake
Degree, hypoimmunity, the invasion of bacterium heresy, humidity hysteresis become expectorant, phlegm stagnating in meridian;" empty " is because nephrons is not solid, deficiency of both QI and blood hypoimmunity;
Take with suppressing the hyperactive liver pathogenic fire purging, eliminating phlegm relieving palpitation, clearing away heat and eliminating phlegm, the Chinese medicine composition treatment having one's ideas straightened out of calming the nerves, and be fabricated to pill, it is simple to take
Treatment, have received obvious therapeutic effect.
Detailed description of the invention
The manufacture method of mad ball fixed to a kind of suppressing the hyperactive liver eliminating phlegm further implements explanation below.
The manufacture method of the fixed mad ball of a kind of suppressing the hyperactive liver eliminating phlegm is produced and is suitable for ten powder charges of a box that a patient takes
Amount is to be made by following method step: raw material of Chinese medicine mass parts ratio one, used: Radix Salviae Miltiorrhizae 12 grams, 30 parts 10 grams of Semen sojae atricolor, life
12 grams of ground, Radix Scrophulariae 10 grams, Radix Achyranthis Bidentatae 10 grams, Rhizoma Acori Graminei 10 grams, Radix Curcumae 10 grams, the Radix Astragali 15 grams, 9 grams of Gypsum Fibrosum, Radix Polygalae 13 grams, Rhizoma Chuanxiong 10
Gram, Arisaema Cum Bile 10 grams, 8 grams of Radix Glycyrrhizae;Two, upper each Chinese medicine powder is broken into mixed powder;Three, hybrid medicine powder is joined with appropriate amount of starch
Share after closing uniformly and be molded into pill.
The fixed mad ball using method of a kind of suppressing the hyperactive liver eliminating phlegm: serious symptom schizophrenic takes a box dose day, serve on a star
The after date state of an illness alleviates can decrement be taken.
Claims (1)
1. a manufacture method for the fixed mad ball of suppressing the hyperactive liver eliminating phlegm, is characterized in that by following each raw material of Chinese medicine and manufacture method: one, used
Raw material of Chinese medicine mass parts ratio: Radix Salviae Miltiorrhizae 12 parts, 30 parts 10 parts of Semen sojae atricolor, 12 parts of the Radix Rehmanniae, Radix Scrophulariae 10 parts, Radix Achyranthis Bidentatae 10 parts, Rhizoma Acori Graminei 10
Part, Radix Curcumae 10 parts, the Radix Astragali 15 parts, 9 parts of Gypsum Fibrosum, Radix Polygalae 13 parts, Rhizoma Chuanxiong 10 parts, Arisaema Cum Bile 10 parts, 8 parts of Radix Glycyrrhizae;Two, by upper each in
Medicated powder is broken into mixed powder;Three, share after hybrid medicine powder being coordinated with appropriate amount of starch uniformly and be molded into pill.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103120787A (en) * | 2013-01-10 | 2013-05-29 | 张立杰 | Traditional Chinese medicine composition for treating decubation of schizophrenia and preparation method thereof |
CN105535845A (en) * | 2016-01-19 | 2016-05-04 | 庞群 | Composition medicine for treating schizophrenia |
CN105688097A (en) * | 2016-04-19 | 2016-06-22 | 劳炳凤 | Medicine for treating depression |
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2016
- 2016-09-30 CN CN201610869022.0A patent/CN106310136A/en not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103120787A (en) * | 2013-01-10 | 2013-05-29 | 张立杰 | Traditional Chinese medicine composition for treating decubation of schizophrenia and preparation method thereof |
CN105535845A (en) * | 2016-01-19 | 2016-05-04 | 庞群 | Composition medicine for treating schizophrenia |
CN105688097A (en) * | 2016-04-19 | 2016-06-22 | 劳炳凤 | Medicine for treating depression |
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Application publication date: 20170111 |