Summary of the invention
Technical problem to be solved by this invention is, the Chinese medicine composition of the amnesia that a kind of neurasthenia of treatment causes is provided, and through nourishing YIN to lower pathogenic fire, tranquilizing mind is fundamentally treated amnesia, to overcome the defective of existing such disease medicine of treatment.
It is following that the present invention solves the problems of the technologies described above the technical scheme that is adopted:
The Chinese medicine composition of the amnesia that a kind of neurasthenia of treatment causes is characterized in that its set of dispense ratio is: Radix Rehmanniae 10-20 part, Radix Scrophulariae 20-30 part, Os Draconis 10-20 part; Magnetitum 10-20 part, Fructus Aurantii (parched) 10-20 part, Radix Glycyrrhizae 10-20 part, unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure 8-12 part; Radix Polygalae 10-20 part, Carapax et Plastrum Testudinis 10-20 part, Rhizoma Anemones Altaicae 10-20 part, Cinnabaris 10-20 part; Radix Angelicae Sinensis 10-20 part, silkworm excrement 10-20 part, Folium Isatidis 8-12 part, described part refers to mass parts;
And be prepared from according to following method:
(1) with the Radix Rehmanniae of ratio, Radix Scrophulariae, Os Draconis, Magnetitum, Fructus Aurantii (parched), Radix Glycyrrhizae, unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, Radix Polygalae, Carapax et Plastrum Testudinis, Rhizoma Anemones Altaicae, Cinnabaris, Radix Angelicae Sinensis, silkworm excrement and Folium Isatidis mix homogeneously are ground into 80 purpose granules;
(2) above-mentioned granule is made as ball with water, becomes the Semen phaseoli radiati size;
(3) with pill in 103-110 ℃ the baking 5-10 minute, be cooled to room temperature;
(4) comprise (3) made pill with rice paper, put into the porcelain altar and imbed undergroundly that ground temperature is 18-26 ℃ of 2 weeks of natural fermentation;
(5) open altar and take out pill, half does for oral use for A seals up for safekeeping, and second half adds the active carbon of 1/2nd weight, and mix homogeneously is B, is distributed into bag, every bag 30 gram; The every clothes of oral A 1.5-2.5 gram, every day 2 times; Get 3 bags of B, hang the front for one bag, put into pillow core sleep usefulness for 2 bags in addition.
The preferred ingredients proportioning is: 15 parts in the Radix Rehmanniae, 25 parts of Radix Scrophulariaes, 15 parts of Os Draconis, 15 parts of Magnetitums, 15 parts of Fructus Aurantii (parched), 15 parts in Radix Glycyrrhizae, 10 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 15 parts of Radix Polygalaes, 15 parts of Carapax et Plastrum Testudiniss, 15 parts of Rhizoma Anemones Altaicaes, 15 parts in Cinnabaris, 15 parts of Radix Angelicae Sinensis, 15 parts of silkworm excrements, 10 parts of Folium Isatidiss.
The main Chinese herbal medicine of prescription of the present invention is according to traditional medicine and modern medicine analysis, and the property of medicine and pharmacological action are following:
The Radix Rehmanniae: meridian distribution of property and flavor: cold; Sweet, bitter; GUIXIN, liver, kidney channel.Function cures mainly: be used for calentura crimson tongue excessive thirst, and interior-heat caused by deficiency of YIN, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis is sent out the speckle dermexanthesis.
Radix Scrophulariae: meridian distribution of property and flavor: be slightly cold; Sweet, bitter, salty; Return lung, stomach, kidney channel.Function cures mainly: removing heat from blood YIN nourishing, eliminating fire and detoxication.Be used for consumption of YIN caused by febrile disease, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Os Draconis: meridian distribution of property and flavor: flat; Sweet, puckery; GUIXIN, liver, kidney channel.Function cures mainly: tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver and subsiding YANG is restrained astringent or styptic treatment for spontaneous sweating.Be used for malaise, palpitation and insomnia, infantile convulsion is demented, dizziness due to hyperactivity of liver-YANG, all cards of slippage.
Magnetitum: meridian distribution of property and flavor: cold; Salty; GUIXIN, liver, kidney channel; Mild toxicity.Function cures mainly: suppressing the hyperactive liver and subsiding YANG, hearing-improing and eyesight improving, tranquillizing the mind by relieving convulsion, helping inspiration to relieve asthma.Be used to have a dizzy spell blurring of vision, Hiccough and deaf, palpitation with fear insomnia, the asthma of suffering from a deficiency of the kidney.
Fructus Aurantii (parched): meridian distribution of property and flavor: temperature; Bitter, hot, sour; Return spleen, stomach warp.Function cures mainly: regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.Be used for the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion stops in the phlegm retention; Gastroptosis, proctoptosis, uterine prolapse.
Radix Glycyrrhizae: meridian distribution of property and flavor: flat; Sweet; GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure: meridian distribution of property and flavor: cold; Sweet, hot, light; GUIXIN, stomach, small intestine meridian.Function cures mainly: clearing heat and relieving fidgetness, the diuresis of promoting the production of body fluid.Be used for the calentura excessive thirst, aphtha dark coloured urine, epidemic febrile disease pathogens intruding into the pericardium, the disease of unconsciousness and delirium.
Radix Polygalae: meridian distribution of property and flavor: temperature; Bitter, hot; GUIXIN, kidney, lung meridian.Function cures mainly: the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm detumescence.Be used for insomnia and dreamful sleep, forgetful palpitation with fear that disarmony between the heart and kidney causes, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Carapax et Plastrum Testudinis: meridian distribution of property and flavor: cold; Sweet, salty; Return liver, kidney, heart channel.Function cures mainly: nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, the reinforcing the heart of nourishing blood.Be used for deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat is had a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, and the muscles and bones flaccidity is soft, and it is forgetful to have a guilty conscience.
Rhizoma Anemones Altaicae: meridian distribution of property and flavor: temperature; Hot, bitter; GUIXIN, stomach warp.Function cures mainly: removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.It is not hungry to be used for the wrist painful abdominal mass, mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.
Cinnabaris: meridian distribution of property and flavor: cold; Sweet; The GUIXIN warp; Poison.Function cures mainly: it is relieving convulsion to clear away heart-fire, the detoxifcation of calming the nerves.Be used for palpitation and being susceptible to fright, insomnia and dreamful sleep, epilepsy is gone mad, infantile convulsion, blurring of vision, aphtha, sore throat, sore swollen toxin.
Radix Angelicae Sinensis: meridian distribution of property and flavor: wet; Sweet, hot; Return liver, the heart, spleen channel.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.The Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.Be used for the amenorrhea dysmenorrhea, rheumatic arthralgia, traumatic injury.
Silkworm excrement: meridian distribution of property and flavor: temperature; Sweet, hot; Return liver, spleen, stomach warp.Function cures mainly: wind-damp dispelling and middleization are turbid.Be used for rheumatic arthralgia, limbs are unsuccessful, the stupid fiber crops of skin, rubella pruritus, the stomachache of the turbid damp internal resistance convulsion of vomiting and diarrhoea, amenorrhea, metrorrhagia etc.
Folium Isatidis: meridian distribution of property and flavor: cold; Bitter; GUIXIN, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Be used for pathogenic warmth and join the army, unconsciousness due to high fever is sent out the speckle dermexanthesis, yellow cellulitis, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.
Active carbon: the present invention is used to adsorb flavour of a drug, slow release pill effective ingredient.
Good effect of the present invention: the traditional Chinese medical science is thought: then the heart-yin loss of excessive thinking, and hyperactivity of fire caused by deficiency of YIN, disarmony between the heart and kidney is so see severe palpitation, dizzy insomnia, seminal emission night sweat, the forgetful grade of dreaminess disease.Carapax et Plastrum Testudinis, Os Draconis YIN nourishing restoring normal coordination between the heart and kidney in the side, tranquilizing mind and with the unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure pathogenic fire reducing; Cinnabaris and Bombyx mori L. refreshment eyesight improving are got rid of evils, and Radix Angelicae Sinensis is kept god, Radix Polygalae and Rhizoma Anemones Altaicae Fructus Alpiniae Oxyphyllae and the sharp key that can eliminate the phlegm; The pathogenic fire purging of quenching one's thirst of the Radix Rehmanniae, Radix Scrophulariae, the Fructus Aurantii (parched) regulating the flow of QI to ease the stomach, Folium Isatidis prevents the pathogenic warmth coma; All medicines are with Radix Glycyrrhizae and close, and the middle natural fermentation of burying.Soil is female among the five elements, absorbs all things on earth; For in, the central authorities of calming the nerves.Prescription of the present invention has Fructus Alpiniae Oxyphyllae, gets rid of evils, calms the nerves, the effect of refreshment, so we are that treatment is because the effective prescription of amnesia that the neurasthenia causes.Can fundamentally treat the amnesia that causes owing to the neurasthenia, and treatment cycle is short, cost is low, and toxic and side effects is little, and therapeutic effect is desirable.
Obtained tangible clinical effectiveness through clinical practice, cure rate reaches 91.5%, and total effective rate reaches 97.9%, no obvious toxic-side effects.
The specific embodiment
Further specify the present invention below in conjunction with concrete preparation instance.
Prescription instance one:
The set of dispense ratio is: 10 parts in the Radix Rehmanniae, 20 parts of Radix Scrophulariaes, 10 parts of Os Draconis, 10 parts of Magnetitums, 10 parts of Fructus Aurantii (parched), 10 parts in Radix Glycyrrhizae, 8 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 10 parts of Radix Polygalaes, 10 parts of Carapax et Plastrum Testudiniss, 10 parts of Rhizoma Anemones Altaicaes, 10 parts in Cinnabaris, 10 parts of Radix Angelicae Sinensis, 10 parts of silkworm excrements, 8 parts of Folium Isatidiss.
Method for preparing:
(1) gets 10 parts of Radix Rehmanniae, 20 portions of Radix Scrophulariaes, 10 parts of Os Draconis, 10 parts of Magnetitums, 10 parts of Fructus Aurantii (parched); 10 portions of Radix Glycyrrhizaes, 8 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 10 parts of Radix Polygalaes, 10 parts of Carapax et Plastrum Testudiniss, 10 portions of Rhizoma Anemones Altaicaes; 10 parts of Cinnabaris, 10 parts of Radix Angelicae Sinensis, 10 parts of silkworm excrements and 8 parts of Folium Isatidis mix homogeneously are ground into 80 purpose granules.
(2) above-mentioned granule is made as ball with water, becomes the Semen phaseoli radiati size.
(3) with pill in 103-110 ℃ the baking 5-10 minute, be cooled to room temperature.
(4) comprise (3) made pill with rice paper, put into the porcelain altar and imbed undergroundly that ground temperature is 18-26 ℃ of 2 weeks of natural fermentation.
(5) open altar and take out pill, half does for oral use for A seals up for safekeeping, and second half adds the active carbon of 1/2nd weight, and mix homogeneously is B, is distributed into bag, and every bag 30 gram gets final product.
Instructions about how to take medicine and usage: the every clothes of oral A 1.5-2.5 gram, every day 2 times.Get 3 bags of B, hang the front for one bag, put into pillow core sleep usefulness for 2 bags in addition.
Prescription instance two:
The set of dispense ratio is: 15 parts in the Radix Rehmanniae, 25 parts of Radix Scrophulariaes, 15 parts of Os Draconis, 15 parts of Magnetitums, 15 parts of Fructus Aurantii (parched), 15 parts in Radix Glycyrrhizae, 10 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 15 parts of Radix Polygalaes, 15 parts of Carapax et Plastrum Testudiniss, 15 parts of Rhizoma Anemones Altaicaes, 15 parts in Cinnabaris, 15 parts of Radix Angelicae Sinensis, 15 parts of silkworm excrements, 10 parts of Folium Isatidiss.
Method for preparing: 15 parts of Radix Rehmanniae are got in (1), 25 portions of Radix Scrophulariaes, 15 parts of Os Draconis, 15 parts of Magnetitums, 15 parts of Fructus Aurantii (parched); 15 portions of Radix Glycyrrhizaes, 10 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 15 parts of Radix Polygalaes, 15 parts of Carapax et Plastrum Testudiniss, 15 portions of Rhizoma Anemones Altaicaes; 15 parts of Cinnabaris, 15 parts of Radix Angelicae Sinensis, 15 parts of silkworm excrements and 10 parts of Folium Isatidis mix homogeneously are ground into 80 purpose granules.
(2) above-mentioned granule is made as ball with water, becomes the Semen phaseoli radiati size.
(3) with pill in 103-110 ℃ the baking 5-10 minute, be cooled to room temperature.
(4) comprise (3) made pill with rice paper, put into the porcelain altar and imbed undergroundly that ground temperature is 18-26 ℃ of 2 weeks of natural fermentation.
(5) open altar and take out pill, half does for oral use for A seals up for safekeeping, and second half adds the active carbon of 1/2nd weight, and mix homogeneously is B, is distributed into bag, and every bag 30 gram gets final product.
Instructions about how to take medicine and usage are with embodiment one.
Prescription instance three:
The set of dispense ratio is: 20 parts in the Radix Rehmanniae, 30 parts of Radix Scrophulariaes, 20 parts of Os Draconis, 20 parts of Magnetitums, 20 parts of Fructus Aurantii (parched), 20 parts in Radix Glycyrrhizae, 12 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 20 parts of Radix Polygalaes, 20 parts of Carapax et Plastrum Testudiniss, 20 parts of Rhizoma Anemones Altaicaes, 20 parts in Cinnabaris, 20 parts of Radix Angelicae Sinensis, 20 parts of silkworm excrements, 12 parts of Folium Isatidiss.
Method for preparing: method for preparing:
(1) gets 20 parts of Radix Rehmanniae, 30 portions of Radix Scrophulariaes, 20 parts of Os Draconis, 20 parts of Magnetitums, 20 parts of Fructus Aurantii (parched); 20 portions of Radix Glycyrrhizaes, 12 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 20 parts of Radix Polygalaes, 20 parts of Carapax et Plastrum Testudiniss, 20 portions of Rhizoma Anemones Altaicaes; 20 parts of Cinnabaris, 20 parts of Radix Angelicae Sinensis, 20 parts of silkworm excrements and 12 parts of Folium Isatidis mix homogeneously are ground into 80 purpose granules.
(2) above-mentioned granule is made as ball with water, becomes the Semen phaseoli radiati size.
(3) with pill in 103-110 ℃ the baking 5-10 minute, be cooled to room temperature.
(4) comprise (3) made pill with rice paper, put into the porcelain altar and imbed undergroundly that ground temperature is 18-26 ℃ of 2 weeks of natural fermentation.
(5) open altar and take out pill, half does for oral use for A seals up for safekeeping, and second half adds the active carbon of 1/2nd weight, and mix homogeneously is B, is distributed into bag, and every bag 30 gram gets final product.
Instructions about how to take medicine and usage are with embodiment one.
It below is clinical report
From year July in July, 2008 to 2010; The application the present invention of Fushan District the People's Hospital writes out a prescription instance two treatments because amnesia 75 examples that the neurasthenia causes to the inventor in Yantai; And with use oral vitamin B1+ adenosine B12+ Piracetam Tablet the same period and treat 30 examples and carry out controlled observation; Receive better effects, existing report as follows.
1, clinical data
Physical data is observed case totally 105 examples, is divided into 2 groups at random.75 examples are organized in treatment, male 30 examples, women 45 examples; Year at age (39.5 ± 15.27); The course of disease (3 ± 1) moon; Matched group 30 examples, male 10 examples, women 20 examples; Year at age (39.5 ± 15.27); The course of disease (3 ± 1) moon.2 groups of physical data are through statistical procedures, and there are no significant that meaning (P>0.05) has comparability for difference.
2, Therapeutic Method
2.1 matched group adopts oral vitamin B1+ adenosine B12+ Piracetam Tablet every day 2 times.1 week of the course of treatment.
2.2 the treatment group adopts the every clothes of oral medicine of the present invention 1.5-2.5 gram, every day, 2 times+medicated pillow+front hung bag, 1 week of the course of treatment.
2.3 dizzy heavy before and after the observation item treatment, sleep situation, memory performance, the morning, noon and afternoon brain situation of regaining consciousness.
2.4 statistical method adopts the SPSS statistical software to analyze.
3, criterion of therapeutical effect and therapeutic outcome
Criterion of therapeutical effect is with reference to relevant criterion of therapeutical effect in " disease of tcm judgement criterion of therapeutical effect ".Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal.Take a turn for the better: clinical symptom relief, lab testing improve or are normal.Invalid: clinical symptoms does not have being clearly better or increases the weight of.
Therapeutic outcome
2 groups of clinical efficacies are relatively seen table 1.Total effective rate treatment group is 87.9%, and matched group is 76.6%, 2 group and compares that difference has significance meaning (P<0.05).
Table 1 liang group clinical efficacy relatively
Group n improvement recovery from illness invalid total effective rate (%)
Treatment organizes 75 13 (17.3%) 53 (70.6%) 9 (12%) 87.9%
Matched group 30 2 (6.6%) 21 (70%) 7 (23.3%) 76.6%
With preceding relatively ※ P<0.01 of treatment; With comparison after the treatment of control group, Δ P<0.01
This shows that medicine of the present invention is superior to other medicines for treatment heatstroke effect, cures the effective percentage height.