CN105535581A - 一种治疗夏季皮炎的药物 - Google Patents

一种治疗夏季皮炎的药物 Download PDF

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CN105535581A
CN105535581A CN201510969219.7A CN201510969219A CN105535581A CN 105535581 A CN105535581 A CN 105535581A CN 201510969219 A CN201510969219 A CN 201510969219A CN 105535581 A CN105535581 A CN 105535581A
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毕新颖
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Abstract

本发明公开了一种治疗夏季皮炎的药物。它由内服汤剂和外洗汤剂组成，内服汤剂由下述原料药制成：人参、黄精、刺五加、酸枣仁、淡竹叶、牡丹皮、红花、川芎、鸡血藤、生地黄、陈皮、白术、浮小麦、荷叶、栀子和甘草；外洗汤剂由下述原料药制成：藿香、白茅根、苦参、白鲜皮、蛇床子、地肤子和生石膏。该药物能快速缓解症状，并防治该病的复发。

Description

一种治疗夏季皮炎的药物
技术领域
本发明涉及一种治疗夏季皮炎的药物，属于中药技术领域。
背景技术
夏季皮炎是由于气候炎热引起的一种季节性的炎症性皮肤病，常在6～8月份发病。夏季皮炎好发于中年偏胖的女性。皮损对称发生于躯干、四肢，尤以小腿伸侧为甚。表现为大片鲜红色斑，在红斑基础上有针头至粟粒大小的丘疹、丘疱疹。伴有剧痒，搔抓后可出现抓痕、血痂，久之皮肤粗糙增厚。夏季皮炎的成因为：出汗是人体在夏天散热的主要方式，而汗液中含有大量人体组织的代谢废物，这些代谢产物多为酸性，长时间滞留在皮肤上就会对皮肤产生较强的刺激，使皮肤产生炎症反应，导致发红、瘙痒等一系列症状。不少患者每到夏季就容易发病，气温下降或至秋凉后炎症又会减轻或消退。
针对夏季皮炎的治疗，有些患者使用抗菌药，但是抗生素及抗真菌药对单纯夏季皮炎的改善起不了多少作用。因为即使皮肤表面存在少量的细菌或真菌，也不是引发夏季皮炎的主要原因。相反，皮肤反复接触不需要的药物，不仅无助于疾病的恢复，反而可能会诱发皮肤过敏。目前比较有效的方式是：外用1％酚炉甘石洗剂、1％薄荷炉甘石洗剂，1％薄荷酒精或糖皮质激素等外用制剂，这些方式也仅仅是缓解夏季皮炎的症状，起不到有效治疗的效果。
发明内容
本发明的目的是克服上述问题，提供一种治疗夏季皮炎的药物。该药物能快速缓解症状，并防治该病的复发。
本发明的技术方案是：一种治疗夏季皮炎的药物，其特征是，由内服汤剂和外洗汤剂组成，
其中内服汤剂由下述重量份的原料药制成：人参10-15、黄精20-25、刺五加10-15、酸枣仁15-20、淡竹叶10-15、牡丹皮15-20、红花8-12、川芎8-12、鸡血藤10-15、生地黄10-15、陈皮8-12、白术5-10、浮小麦8-12、荷叶8-12、栀子5-10和甘草3-8；水煎煮制备；
其中外洗汤剂由下述重量份的原料药制成：藿香10-15、白茅根8-12、苦参8-12、白鲜皮8-12、蛇床子5-10、地肤子5-10和生石膏15-25；水煎煮制备。
优选的，所述内服汤剂由下述重量份的原料药制成：人参12、黄精22、刺五加12、酸枣仁18、淡竹叶12、牡丹皮18、红花10、川芎10、鸡血藤12、生地黄12、陈皮10、白术8、浮小麦10、荷叶10、栀子8和甘草5。
优选的，所述外洗汤剂由下述重量份的原料药制成：藿香12、白茅根10、苦参10、白鲜皮10、蛇床子8、地肤子8和生石膏20。
配制及服用方法：内服汤剂分两次早晚服用；外洗汤剂凉至30-38℃后采用纱布蘸取药液擦拭患处(患处预先用温水洗净擦干)，每日3-5次。3天为一个疗程。
各中药药理作用：
人参：甘、微苦，微温。归脾、肺、心、肾经。功能与主治：大补元气，复脉固脱，补脾益肺，生津养血，安神益智。用于体虚欲脱，肢冷脉微，脾虚食少，肺虚喘咳，津伤口渴，内热消渴，气血亏虚，久病虚赢，惊悸失眠，阳痿宫冷。
黄精：甘，平。归脾、肺、肾经。功能与主治：补气养阴，健脾，润肺，益肾。用于脾胃气虚，体倦乏力，胃阴不足，口干食少，肺虚燥咳，劳嗽咳血，精血不足，腰膝酸软，须发早白，内热消渴。
刺五加：辛、微苦，温。归脾、肾、心经。功能与主治：益气健脾，补肾安神。用于脾肺气虚，体虚乏力，食欲不振，肺肾两虚，久咳虚喘，肾虚腰膝酸痛，心脾不足，失眠多梦。
酸枣仁：甘、酸，平。归肝、胆、心经。功能与主治：养心补肝，宁心安神，敛汗，生津。用于虚烦不眠，惊悸多梦，体虚多汗，津伤口渴。
淡竹叶：甘、淡，寒。归心、胃、小肠经。功能与主治：清热泻火，除烦止渴，利尿通淋。用于热病烦渴，小便短赤涩痛，口舌生疮。
牡丹皮：苦、辛，微寒。归心、肝、肾经。功能与主治：清热凉血，活血化瘀。用于热入营血，温毒发斑，吐血衄血，夜热早凉，无汗骨蒸，经闭痛经，跌扑伤痛，痈肿疮毒。
红花：辛，温。入心、肝经。活血通经，去瘀止痛。治经闭，癥瘕，难产，死胎，产后恶露不行、瘀血作痛，痈肿，跌扑损伤。
川芎：味辛，性温。归肝、胆、心包经。功效：活血祛瘀；行气开郁；祛风止痛。
鸡血藤：苦、甘，温。归肝、肾经。功能与主治：活血补血，调经止痛，舒筋活络。用于月经不调，痛经，经闭，风湿痹痛，麻木瘫痪，血虚萎黄。
生地黄：生地黄清热凉血，养阴生津。用于热入营血，温毒发斑，吐血衄血，热病伤阴，舌绛烦渴，津伤便秘，阴虚发热，骨蒸劳热，内热消渴。
陈皮：苦、辛，温。归肺、脾经。功能与主治：理气健脾，燥湿化痰。用于脘腹胀满，食少吐泻，咳嗽痰多。
白术：苦、甘，温。归脾、胃经。功能与主治：健脾益气，燥湿利水，止汗，安胎。用于脾虚食少，腹胀泄泻，痰饮眩悸，水肿，自汗，胎动不安。
浮小麦：味甘；性凉。除虚热；止汗。主治：阴虚发热；盗汗；自汗。用于体虚多汗，脏躁症。
荷叶：苦，平。归肝、脾、胃经。功能与主治：清暑化湿，升发清阳，凉血止血。用于暑热烦渴，暑湿泄泻，脾虚泄泻，血热吐衄，便血崩漏。
栀子：苦，寒。归心、肺、三焦经。功能与主治：泻火除烦，清热利湿，凉血解毒；外用消肿止痛。用于热病心烦，湿热黄疸，淋证涩痛，血热吐衄，目赤肿痛，火毒疮疡，外治扭挫伤痛。
甘草：甘，平。归心、肺、脾、胃经。功能与主治：补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
广藿香：辛，微温。归脾、胃、肺经。功能与主治：芳香化浊，和中止呕，发表解暑。用于湿浊中阻，脘痞呕吐，暑湿表证，湿温初起，发热倦怠，胸闷不舒，寒湿闭暑，腹痛吐泻，鼻渊头痛。
白茅根：甘，寒。归肺、胃、膀胱经。功能主治：凉血止血，清热利尿。用于血热吐血，衄血，尿血，热病烦渴，黄疸，水肿，热淋涩痛；急性肾炎水肿。
苦参：苦，寒。归心、肝、胃、大肠、膀胱经。功能与主治：清热燥湿，杀虫，利尿。用于热痢，便血，黄疸尿闭，赤白带下，阴肿阴痒，湿疹，湿疮，皮肤瘙痒，疥癣麻风，外治滴虫性阴道炎。
白鲜皮：苦，寒。归脾、胃、膀胱经。功能与主治：清热燥湿，祛风解毒。用于湿热疮毒，黄水淋漓，湿疹，风疹，疥癣疮癞，风湿热痹，黄疸尿赤。
蛇床子：辛、苦，温；有小毒。归肾经。功能主治：温肾壮阳，燥湿，祛风，杀虫。用于阳痿，宫冷，寒湿带下，湿痹腰痛；外治外阴湿疹，妇人阴痒；滴虫性阴道炎。
地肤子：辛、苦，寒。归肾、膀胱经。功能与主治：清热利湿，祛风止痒。用于小便涩痛，阴痒带下，风疹，湿疹，皮肤瘙痒。
生石膏：生石膏性凉而能散，解肌清热，除烦止渴，清中有宣透的作用，有解热清胃火之效，为退热之圣药。
中医认为：夏季皮炎是由于内蕴湿热，外受暑热相感而生。本发明以上述原料组方，内服药益气健脾养阴、凉血通脉、镇静安神、清暑热、敛汗。本发明内服药益气健脾养阴、凉血通脉以解决患者体虚易出汗的根本问题。镇静安神以解决患者因烦躁、紧张等情绪导致夏季皮炎产生及加大治愈难度的问题。清暑热、敛汗从而减少汗液的排出。本发明的外用洗药，清热燥湿、凉血解毒、止痒，以消除夏季皮炎的外在症状。
本发明的有益效果是：本发明采用内服加外洗的方式治疗夏季皮炎，疗效好，临床总有效率为100％。
以下结合临床资料及典型病例对本发明的有益效果进一步说明。
一、临床观察
1、临床资料：选自2014年6月1日至2014年8月31日，具有完整资料的门诊夏季皮炎患者135例进行临床观察，其中男31例，女104例。年龄在18-65岁之间。所选病例均无其他系统性疾病。
2、诊断标准：根据本病有明显的季节性，皮疹为大片红斑基础上的丘疹、丘疱疹，有剧痒，天气转凉后可自然减轻或消退的特点进行诊断。
3、治疗方法：采用本发明的内服加外洗的方式进行治疗，3天为1个疗程。
4、治疗结果：痊愈95例(皮疹全部消退，瘙痒消失)；好转33例(皮疹消退50％～70％，瘙痒基本消失)；有效7例(皮疹消退30％～50％，瘙痒好转)；无效0例(皮疹未退，瘙痒仍明显)。总有效率100％。所有痊愈的95例患者中，在天气炎热时再次复发的仅有2例，复发率低。
二、典型病例
病例1：梁某某，女，45岁。患者多年来反复发作夏季皮炎，夏季天气闷热出汗较多时，患者的胳膊、后背和颈部就会出现大片鲜红色斑，并具有针头至粟粒大小的丘疹。伴有剧痒，晚上痒的睡不着觉。曾使用1％酚炉甘石洗剂擦洗，效果不佳。经采用本发明的内服加外洗方式治疗后2个疗程后，患者的症状明显减轻，继续服用2个疗程治愈，随访1年未复发。
病例2：齐某，男，58岁。患者一到夏季，颈部、胳膊的前肘、小腿和后背就起鲜红色疙瘩，并具有针头至粟粒大小的丘疱疹，同时瘙痒难耐，经常痒的整夜睡不着觉，而且容易挠破出血。经采用本发明的内服加外洗方式治疗后3个疗程后，患者的症状明显减轻，继续服用2个疗程治愈，随访1年未复发。
具体实施方式
实施例1
内服汤剂(单位：克)：人参12、黄精22、刺五加12、酸枣仁18、淡竹叶12、牡丹皮18、红花10、川芎10、鸡血藤12、生地黄12、陈皮10、白术8、浮小麦10、荷叶10、栀子8和甘草5；
外洗汤剂(单位：克)：藿香12、白茅根10、苦参10、白鲜皮10、蛇床子8、地肤子8和生石膏20。
配制及服用方法：内服汤剂水煎煮，分两次早晚服用；外洗汤剂水煎煮，凉至30-38℃后采用纱布蘸取药液擦拭患处(患处预先用温水洗净擦干)，每日3-5次。3天为一个疗程。
实施例2
内服汤剂(单位：克)：人参15、黄精25、刺五加15、酸枣仁20、淡竹叶15、牡丹皮20、红花12、川芎12、鸡血藤15、生地黄15、陈皮12、白术10、浮小麦12、荷叶12、栀子10和甘草5；
外洗汤剂(单位：克)：藿香15、白茅根12、苦参12、白鲜皮12、蛇床子10、地肤子10和生石膏25。
配制及服用方法：同实施例1。
实施例3
内服汤剂(单位：克)：人参10、黄精20、刺五加10、酸枣仁15、淡竹叶10、牡丹皮15、红花8、川芎8、鸡血藤10、生地黄10、陈皮8、白术5、浮小麦8、荷叶8、栀子5和甘草5；
外洗汤剂(单位：克)：藿香10、白茅根8、苦参8、白鲜皮8、蛇床子5、地肤子5和生石膏15。
配制及服用方法：同实施例1。
实施例4
内服汤剂(单位：克)：人参15、黄精25、刺五加10、酸枣仁18、淡竹叶10、牡丹皮15、红花8、川芎8、鸡血藤12、生地黄12、陈皮10、白术6、浮小麦10、荷叶12、栀子8和甘草5；
外洗汤剂(单位：克)：藿香12、白茅根12、苦参8、白鲜皮10、蛇床子7、地肤子8和生石膏20。
配制及服用方法：同实施例1。

Claims (3)

1.一种治疗夏季皮炎的药物，其特征是，由内服汤剂和外洗汤剂组成，
所述内服汤剂由下述重量份的原料药制成：人参10-15、黄精20-25、刺五加10-15、酸枣仁15-20、淡竹叶10-15、牡丹皮15-20、红花8-12、川芎8-12、鸡血藤10-15、生地黄10-15、陈皮8-12、白术5-10、浮小麦8-12、荷叶8-12、栀子5-10和甘草3-8；水煎煮制备；
所述外洗汤剂由下述重量份的原料药制成：藿香10-15、白茅根8-12、苦参8-12、白鲜皮8-12、蛇床子5-10、地肤子5-10和生石膏15-25；水煎煮制备。
2.如权利要求1所述的一种治疗夏季皮炎的药物，其特征是，所述内服汤剂由下述重量份的原料药制成：人参12、黄精22、刺五加12、酸枣仁18、淡竹叶12、牡丹皮18、红花10、川芎10、鸡血藤12、生地黄12、陈皮10、白术8、浮小麦10、荷叶10、栀子8和甘草5。
3.如权利要求1或2所述的一种治疗夏季皮炎的药物，其特征是，所述外洗汤剂由下述重量份的原料药制成：藿香12、白茅根10、苦参10、白鲜皮10、蛇床子8、地肤子8和生石膏20。
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