CN105535413A - Health food composition with anti-alcohol hangover effect and auxiliary protection effect on chemical liver injury - Google Patents
Health food composition with anti-alcohol hangover effect and auxiliary protection effect on chemical liver injury Download PDFInfo
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- 239000000203 mixture Substances 0.000 title claims abstract description 34
- 231100000753 hepatic injury Toxicity 0.000 title claims abstract description 19
- 239000000126 substance Substances 0.000 title claims abstract description 15
- 206010067125 Liver injury Diseases 0.000 title claims abstract description 14
- 230000000694 effects Effects 0.000 title claims abstract description 9
- 235000013402 health food Nutrition 0.000 title claims abstract description 8
- 206010019133 Hangover Diseases 0.000 title abstract 2
- 230000002075 anti-alcohol Effects 0.000 title abstract 2
- 239000003814 drug Substances 0.000 claims abstract description 32
- 238000002360 preparation method Methods 0.000 claims abstract description 24
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 9
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 46
- 239000013543 active substance Substances 0.000 claims description 14
- 239000000706 filtrate Substances 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 11
- 239000012567 medical material Substances 0.000 claims description 9
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 8
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 8
- 239000012141 concentrate Substances 0.000 claims description 7
- 238000009472 formulation Methods 0.000 claims description 7
- 238000004321 preservation Methods 0.000 claims description 7
- 239000006187 pill Substances 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 5
- 239000008187 granular material Substances 0.000 claims description 5
- 239000002994 raw material Substances 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 3
- 239000003826 tablet Substances 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000000463 material Substances 0.000 abstract description 3
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 241000234435 Lilium Species 0.000 abstract 1
- 244000236658 Paeonia lactiflora Species 0.000 abstract 1
- 235000008598 Paeonia lactiflora Nutrition 0.000 abstract 1
- 244000197580 Poria cocos Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 241001121987 Scrophularia ningpoensis Species 0.000 abstract 1
- 240000001398 Typha domingensis Species 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 description 9
- 229940079593 drug Drugs 0.000 description 6
- 235000013305 food Nutrition 0.000 description 5
- 241000700159 Rattus Species 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 3
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
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- 239000003795 chemical substances by application Substances 0.000 description 1
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- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000014510 cooky Nutrition 0.000 description 1
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- 235000013399 edible fruits Nutrition 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 230000009246 food effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 210000002767 hepatic artery Anatomy 0.000 description 1
- 231100000234 hepatic damage Toxicity 0.000 description 1
- 230000007866 hepatic necrosis Effects 0.000 description 1
- 206010019692 hepatic necrosis Diseases 0.000 description 1
- 210000002989 hepatic vein Anatomy 0.000 description 1
- 231100000334 hepatotoxic Toxicity 0.000 description 1
- 230000001553 hepatotropic effect Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 230000008818 liver damage Effects 0.000 description 1
- 235000011475 lollipops Nutrition 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
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- 231100000915 pathological change Toxicity 0.000 description 1
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- 239000000546 pharmaceutical excipient Substances 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/808—Scrophularia (figwort)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to an application of a traditional Chinese medicine composition in preparation of health food with an anti-alcohol hangover effect and an auxiliary protection effect on a chemical liver injury. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 30-80 parts of lily, 30-80 parts of poria cocos, 40-90 parts of scrophularia ningpoensis, 30-80 parts of ligusticum wallichii, 20-60 parts of rhizoma alismatis, 5-30 parts of panax notoginseng, 10-50 parts of rhizoma atractylodis macrocephalae, 20-60 parts of angelica sinensis, 20-60 parts of cattail pollen and 120-180 parts of white peony roots.
Description
Invention field
The present invention relates to a kind of preparation method of Chinese medicine and health food compositions, particularly there is the pharmaceutical preparation of relieving the effect of alcohol, chemical liver injury being had to the preparation method of the health-care food composition of auxiliary protection function and preparing by the method.
Background technology
The hepatic injury caused by chemical Hepatoxic substance.These chemical substances comprise chemical toxicant in ethanol, environment and some drugs.As the liver of the important removing toxic substances organ of human body, there is Hepatic artery and hepatic vein double blood supply.Chemical substance enters liver by gastrointestinal tract portal vein or body circulation and transforms, and therefore liver is easily subject to the toxicant infringement in chemicals.All there are some to the virose material of liver in the Nature and human industry's production process, be called " hepatotropic poison ", these poisonous substances are general susceptible in crowd, incubation period is short; the process of pathological changes is directly related with the dosage of infection, can cause liver hepatic necrosis in various degree, fat distortion, liver cirrhosis and hepatocarcinoma.
Hepatic injury is the disease of clinical common harm humans health.Hepatic injury is exactly the invasion that liver is subject to extraneous factor, thus the liver caused is by suitable.Hepatic injury is divided into pathologic hepatic injury and chemical liver injury.Chinese medicine, through the developmental research of several thousand, has certain short regeneration and repair to hepatic injury, therefore uses Chinese medicine Comprehensive Treatment to have unique advantage, can take single medicinal material or compound recipe.
The present inventor finds in clinical and production practices; prior art formula amount is large; medical material waste is serious; oral difficulty; and do not report that above-mentioned preparation had the effect of the health food relieving the effect of alcohol, chemical liver injury is had to auxiliary protection function; the present invention improves formula on the basis of existing technology, deletes the expensive medical material of part, the research work adopt the Chinese crude drug of medicine-food two-purpose in formula, having carried out in health food.The present invention, through experimentation, finds unexpectedly, and formula of the present invention has the health food effect of relieving the effect of alcohol, chemical liver injury being had to auxiliary protection function, thus completes the present invention.
Summary of the invention:
The invention provides a kind of Chinese medicine composition preparation have relieve the effect of alcohol, the application had chemical liver injury in the health food of auxiliary protection function,
Described Chinese medicine composition is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
Bulbus Lilii 30-80 weight portion, Poria 30-80 weight portion, Radix Scrophulariae 40-90 weight portion, Rhizoma Chuanxiong 30-80 weight portion, Rhizoma Alismatis 20-60 weight portion, Radix Notoginseng 5-30 weight portion, Rhizoma Atractylodis Macrocephalae 10-50 weight portion, Radix Angelicae Sinensis 20-60 weight portion, Pollen Typhae 20-60 weight portion, Radix Paeoniae Alba 120-180 weight portion
Preferably, described Chinese medicine composition is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
Bulbus Lilii 60 weight portion, Poria 60 weight portion, Radix Scrophulariae 75 weight portion, Rhizoma Chuanxiong 45 weight portion, Rhizoma Alismatis 45 weight portion, Radix Notoginseng 15 weight portion, the Rhizoma Atractylodis Macrocephalae 30 weight portion, Radix Angelicae Sinensis 45 weight portion, Pollen Typhae 45 weight portion, the Radix Paeoniae Alba 150 weight portion
More than in composition, weight calculates with crude drug, more than composition is by weight as proportioning, can increase according to corresponding proportion when producing or reduce, as large-scale production can by kilogram in units of, or in units of ton, small-scale production also can by gram or milligram in units of, weight can increase or reduce, but the constant rate of raw medicinal herbs weight proportion between each composition.
Compositions of the present invention, preferred preparation method, step is as follows:
Medical material decocts with water 1-3 time, each 1.5-3 hour, collecting decoction, and filter, filtrate is concentrated in right amount, add ethanol, make alcohol content reach 60-80%, leave standstill, filter, reclaim ethanol, filtrate concentrates, and add water cold preservation, filters, obtains active substance, be then prepared into Halth-care composition.
Most preferred, described Chinese medicine composition preparation method step is as follows:
Medical material decocts with water 2 times, each 2 hours, collecting decoction, and filter, filtrate is concentrated in right amount, adds ethanol, make alcohol content reach 7%, leave standstill, filter, reclaim ethanol, filtrate concentrates, add water cold preservation, filters, obtain active substance, through formulation method, be then prepared into Halth-care composition.
The preparation of said products can adopt conventional manufacturing techniques, as using active substance of the present invention as active component, adds adjuvant if desired, as sweeting agent, correctives, the galenic pharmacy routine techniques such as excipient is prepared into tablet, capsule etc., or be prepared into food with food routine techniques.Compositions of the present invention can be that any one is applicable to oral dosage form, as tablet, and capsule, granule, oral liquid, powder, pills etc., also can be prepared into applicable edible food form, as caked sugar, cookies, milk product, ice lolly, bread, fruit jam etc.
Fang Zhong, Bulbus Lilii, Radix Scrophulariae yin nourishing stomach reinforcing are monarch drug, and Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Chuanxiong, Pollen Typhae, Radix Notoginseng blood nourishing acupuncture-stimulating are accessory drugs, and the Rhizoma Atractylodis Macrocephalae, Poria, Rhizoma Alismatis invigorating spleen to remove dampness are adjuvant drug, QI and blood is prosperous, taste and, naturally pain only disease remove.Experiment proved kind conventional amount used use safety, in side, composition cooperatively interacts and has synergistic function.
Compared to the prior art, difference is method of the present invention, provides a kind of new purposes, below by way of experimental data, beneficial effect of the present invention is described:
To the protective effect of alcohol-induced liver injury in rats
One, medicine and grouping:
Model group,
Blank group, normal saline,
The pharmaceutically active substance of the embodiment of the present invention 1, being divided into large, medium and small three dosage component Wei 100mg/kg, 50mg/kg, 10mg/kg
Two, experimental technique
Alcohol-induced liver injury in rats model is set up by Chinese liquor gavage, treatment group gives medicine respectively, matched group gives 0.9% normal saline, continuous 8 weeks, measure the content of serum glutamic oxalacetic transaminase (AST), glutamate pyruvate transaminase (ALT) and triacylglycerol (TG), and the histopathology of observing liver changes.
Three: experimental result:
See the following form:
Table 1, protective effect to alcohol-induced liver injury in rats
Result: each group all significantly can be reduced rat blood serum AST, ALT and TG content, and comparing with liver injury model group has significant difference, liver histopathology changes comparatively liver damage model group and significantly alleviates.
Detailed description of the invention:
Further illustrate the present invention by the following examples, but not as limitation of the present invention.
Embodiment 1
Embodiment 1
Bulbus Lilii 60 weight portion, Poria 60 weight portion, Radix Scrophulariae 75 weight portion, Rhizoma Chuanxiong 45 weight portion, Endothelium Corneum Gigeriae Galli 15 weight portion, Rhizoma Alismatis 45 weight portion, Radix Notoginseng 15 weight portion, the Rhizoma Atractylodis Macrocephalae 30 weight portion, Radix Angelicae Sinensis 45 weight portion, Radix Sanguisorbae 75 weight portion, Pollen Typhae 45 weight portion, the Radix Paeoniae Alba 150 weight portion, Herba Dendrobii 75 weight portion.
Its preparation method is as follows:
Medical material decocts with water 2 times, each 2 hours, collecting decoction, and filter, filtrate is concentrated in right amount, add ethanol, make alcohol content reach 70%, leave standstill, filter, reclaim ethanol, filtrate concentrates, and add water cold preservation, filters, obtains active substance, be prepared into pill further according to galenic pharmacy routine techniques.
Embodiment 2
Bulbus Lilii 30 weight portion, Poria 30 weight portion, Radix Scrophulariae 40 weight portion, Rhizoma Chuanxiong 30 weight portion, Rhizoma Alismatis 20 weight portion, Radix Notoginseng 5 weight portion, the Rhizoma Atractylodis Macrocephalae 10 weight portion, Radix Angelicae Sinensis 20 weight portion, Pollen Typhae 20 weight portion, the Radix Paeoniae Alba 120 weight portion
Its preparation method is as follows:
Medical material decocts with water 1 time, each 1.5 hours, collecting decoction, and filter, filtrate is concentrated in right amount, add ethanol, make alcohol content reach 60%, leave standstill, filter, reclaim ethanol, filtrate concentrates, and add water cold preservation, filters, obtains active substance, be prepared into tablet further according to galenic pharmacy routine techniques.
Embodiment 3
Bulbus Lilii 80 weight portion, Poria 80 weight portion, Radix Scrophulariae 90 weight portion, Rhizoma Chuanxiong 80 weight portion, Rhizoma Alismatis 60 weight portion, Radix Notoginseng 30 weight portion, the Rhizoma Atractylodis Macrocephalae 50 weight portion, Radix Angelicae Sinensis 60 weight portion, Pollen Typhae 60 weight portion, the Radix Paeoniae Alba 180 weight portion
Its preparation method is as follows:
Medical material decocts with water 3 times, each 3 hours, collecting decoction, and filter, filtrate is concentrated in right amount, add ethanol, make alcohol content reach 80%, leave standstill, filter, reclaim ethanol, filtrate concentrates, and add water cold preservation, filters, obtains active substance, be prepared into granule further according to galenic pharmacy routine techniques.
Embodiment 4
The preparation of capsule
The pharmaceutically active substance that Example 1 obtains, through the formulation preparation method of routine, is prepared into capsule
Embodiment 5
The preparation of tablet
The pharmaceutically active substance that Example 1 obtains, through the formulation preparation method of routine, is prepared into tablet
Embodiment 6
The preparation of pill
The pharmaceutically active substance that Example 1 obtains, through the formulation preparation method of routine, is prepared into pill
Embodiment 7
The preparation of granule
The pharmaceutically active substance that Example 1 obtains, through the formulation preparation method of routine, is prepared into granule
Embodiment 8
The preparation of oral liquid
The pharmaceutically active substance that Example 1 obtains, through the formulation preparation method of routine, is prepared into oral solutions.
Claims (6)
1. Chinese medicine composition preparation have relieve the effect of alcohol, the application had chemical liver injury in the health food of auxiliary protection function, described Chinese medicine composition is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
Bulbus Lilii 30-80 weight portion, Poria 30-80 weight portion, Radix Scrophulariae 40-90 weight portion, Rhizoma Chuanxiong 30-80 weight portion, Rhizoma Alismatis 20-60 weight portion, Radix Notoginseng 5-30 weight portion, Rhizoma Atractylodis Macrocephalae 10-50 weight portion, Radix Angelicae Sinensis 20-60 weight portion, Pollen Typhae 20-60 weight portion, Radix Paeoniae Alba 120-180 weight portion.
2. application according to claim 1, is characterized in that, described Chinese medicine composition is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
Bulbus Lilii 60 weight portion, Poria 60 weight portion, Radix Scrophulariae 75 weight portion, Rhizoma Chuanxiong 45 weight portion, Rhizoma Alismatis 45 weight portion, Radix Notoginseng 15 weight portion, the Rhizoma Atractylodis Macrocephalae 30 weight portion, Radix Angelicae Sinensis 45 weight portion, Pollen Typhae 45 weight portion, the Radix Paeoniae Alba 150 weight portion.
3. application according to claim 1, is characterized in that, wherein said Chinese medicine composition preparation method step is as follows:
Medical material decocts with water 1-3 time, each 1.5-3 hour, collecting decoction, and filter, filtrate is concentrated in right amount, add ethanol, make alcohol content reach 60-80%, leave standstill, filter, reclaim ethanol, filtrate concentrates, and add water cold preservation, filters, obtains active substance, be then prepared into Halth-care composition.
4. application according to claim 3, is characterized in that, wherein said Chinese medicine composition preparation method step is as follows:
Medical material decocts with water 2 times, each 2 hours, collecting decoction, and filter, filtrate is concentrated in right amount, adds ethanol, make alcohol content reach 7%, leave standstill, filter, reclaim ethanol, filtrate concentrates, add water cold preservation, filters, obtain active substance, through formulation method, be then prepared into Halth-care composition.
5. application according to claim 1, is characterized in that, described Chinese medicine composition is the pharmaceutical dosage form that any one can be taken.
6. application according to claim 1, is characterized in that, described Chinese medicine composition is capsule, tablet, pill, granule, oral liquid, drop pill, unguentum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511019943.XA CN105535413A (en) | 2015-12-30 | 2015-12-30 | Health food composition with anti-alcohol hangover effect and auxiliary protection effect on chemical liver injury |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20110112925A (en) * | 2010-04-08 | 2011-10-14 | 추교인 | The hangover solution composition and it's manufacturing method |
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| KR20110112925A (en) * | 2010-04-08 | 2011-10-14 | 추교인 | The hangover solution composition and it's manufacturing method |
Non-Patent Citations (2)
| Title |
|---|
| 苏振武: "《医院常用药物手册》", 30 June 2011, 军事医学科学出版社 * |
| 郭爱玲: "曲美布汀与摩罗丹联用治疗功能性消化不良疗效观察", 《世界最新医学信息文摘》 * |
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Application publication date: 20160504 |