CN105535400A - Traditional Chinese medicine composition for treating constipation - Google Patents
Traditional Chinese medicine composition for treating constipation Download PDFInfo
- Publication number
- CN105535400A CN105535400A CN201610098154.8A CN201610098154A CN105535400A CN 105535400 A CN105535400 A CN 105535400A CN 201610098154 A CN201610098154 A CN 201610098154A CN 105535400 A CN105535400 A CN 105535400A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine composition
- radix
- constipation
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine composition for treating constipation. The composition is mainly prepared from radix paeoniae alba, asparagus cochinchinensis, Mangnolia officinalis, semen trichosanthis, immature bitter orange, radix glycyrrhizae, bluestone, raw rhubarb, rhizoma alismatis and elecampane. The traditional Chinese medicine composition has the good treatment effect on chronic functional constipation.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of constipation, belong to technical field of Chinese medicines.
Background technology
Functional constipation be one group change with defecation quality, difficult defecation or defecation is felt not to the utmost, the dry and hard disease for main manifestations of feces, and through various inspections eliminating organic disease.Constipation is a kind of commonly encountered diseases, caused by many reasons.In recent years, along with the raising of people's living standard, the change of dietary structure, the impact of spirit, psychology and society factor, the incidence rate of stasis type constipation increases increasingly, seriously affects quality of life of modern and healthy.In Europe and Oceania, constipation sickness rate is up to 19.8%, and the constipation incidence rate of southern US crowd is between 12-19%, and main cause is gastrointestinal function caused by abnormal.In addition, prolonged constipation can secondary hemorrhoid, bring out cardiovascular and cerebrovascular disease, cause the temperament and interest such as anxiety, depression abnormal, have a strong impact on the quality of life of patient.
For the treatment of constipation, main point Drug therapy and non-drug therapy two kinds at present.Drug therapy mainly comprises various cathartic, short gastrointestinal motivity medicine, cellulose preparation etc., and traditional Western medicine easily tolerates.Chinese medicine constipation has history of more than one thousand years, and it seems to have potential advantages compared to traditional Western medicine.But it is larger about the clinical report result difference of Chinese medicine effect at present.
Summary of the invention
For prior art Problems existing, the object of this invention is to provide a kind of Chinese medicine composition effectively treating constipation.
The technical solution adopted in the present invention is as follows:
A kind of Chinese medicine composition for the treatment of rhinitis, it is characterized in that, this Chinese medicine composition is made up of according to weight proportion following raw materials according medicine: Radix Paeoniae Alba 10-15 part, Radix Asparagi 10-15 part, Cortex Magnoliae Officinalis 10-15 part, Semen Trichosanthis 10-15 part, Fructus Aurantii Immaturus 8-12 part, Radix Glycyrrhizae 5-9 part, Chalcanthitum 5-8 part, Radix Et Rhizoma Rhei 15-25 part, Rhizoma Alismatis 1-5 part, Radix Aucklandiae 6-15 part.
As further preferred technical scheme, described Chinese medicine composition is made up of according to weight proportion following raw materials according medicine: the Radix Paeoniae Alba 10 parts, Radix Asparagi 10 parts, Cortex Magnoliae Officinalis 10 parts, Semen Trichosanthis 10 parts, Fructus Aurantii Immaturus 8 parts, 5 parts, Radix Glycyrrhizae, 5 parts, Chalcanthitum, Radix Et Rhizoma Rhei 15 parts, Rhizoma Alismatis 1 part, the Radix Aucklandiae 6 parts.
This Chinese medicine composition is prepared from by following method: take each composition Chinese crude drug by proportioning, add water and decoct extraction together, merges and decoct extracting solution, filters, concentrated, centrifugal, dry, obtained dry extract.
Described Chinese medicine composition can be used for preparing any conventional oral dosage form, comprises tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, sucks agent, granule, electuary, pill, powder etc.
Colon shows by experiment, and the use of above-mentioned Chinese medicine composition significantly improves the Colonic transit activity of patient, has a significant effect to the treatment of functional constipation.
Detailed description of the invention
Each medical material described in following embodiment is through processed such as clean system, cutting, the process of preparing Chinese medicine, pulverizing, and before feeding intake, through qualification, each herbal medicine material object conforms to title, and quality meets state-promulgated pharmacopoeia standard (concrete Med Mat Appreciation method performs with reference to standards of pharmacopoeia)
Embodiment 1
Take Radix Paeoniae Alba 100g, Radix Asparagi 100g, Cortex Magnoliae Officinalis 100g, Semen Trichosanthis 100g, Fructus Aurantii Immaturus 80g, Radix Glycyrrhizae 50g, Chalcanthitum 50g, Radix Et Rhizoma Rhei 150g, Rhizoma Alismatis 10g, Radix Aucklandiae 60g, add water and decoct extraction together: add water 10L, decoct 2 hours; By decoction extracting liquid filtering, be concentrated into 20
orelative density during C is 1.059; Under 3000rpm rotating speed centrifugal 5 minutes; 80
oc spraying dry, obtains dry extract.
Embodiment 2
Take Radix Paeoniae Alba 150g, Radix Asparagi 150g, Cortex Magnoliae Officinalis 150g, Semen Trichosanthis 150g, Fructus Aurantii Immaturus 120g, Radix Glycyrrhizae 90g, Chalcanthitum 80g, Radix Et Rhizoma Rhei 250g, Rhizoma Alismatis 50g, Radix Aucklandiae 150g, add water and decoct extraction together: add water 10L, decoct 2 hours; By decoction extracting liquid filtering, be concentrated into 20
orelative density during C is 1.059; Under 3000rpm rotating speed centrifugal 5 minutes; 80
oc spraying dry, obtains dry extract.
Embodiment 3
Take Radix Paeoniae Alba 120g, Radix Asparagi 120g, Cortex Magnoliae Officinalis 120g, Semen Trichosanthis 120g, Fructus Aurantii Immaturus 100g, Radix Glycyrrhizae 70g, Chalcanthitum 60g, Radix Et Rhizoma Rhei 200g, Rhizoma Alismatis 30g, Radix Aucklandiae 100g, add water and decoct extraction together: add water 10L, decoct 2 hours; By decoction extracting liquid filtering, be concentrated into 20
orelative density during C is 1.059; Under 3000rpm rotating speed centrifugal 5 minutes; 80
oc spraying dry, obtains dry extract.Said preparation is used for ensuing colon by experiment.
Embodiment 4 colon by experiment
Healthy and each 20 examples of Patients with Functional Constipation complete control experiment, and wherein respectively organize M-F identical, the age is without the significance difference opposite sex.The diagnostic criteria of Patients with Functional Constipation is Rome II standard: the defecation of following 2 or multinomial: more than (1) 1/4 time that had at least 12 weeks 12 middle of the month (can be discontinuous) is in the past required great effort; More than (2) 1/4 time feces are in block or scleroma; More than (3) 1/4 time defecations have anal orifice and rectal intestine to block sense when not feeling to the greatest extent more than (4) 1/4 time defecation; More than (5) 1/4 time defecations must help by maneuver (as point stingy, prop up pelvic floor); More than (6) 1/4 times weekly defecation be less than 3 times, there is not loose stool, the standard of inadequate IBS; Except intestinal or whole body organic diseases because of and medicine factor.
Colon absorption detects: in check first 1 week inactive all may affect the medicine of digestive tract function, keep normal diet, live and work to be accustomed to.Check the first 1 day morning (after the meal early) oral 20 the barium bars of 8:00, then take the photograph plain abdominal radiograph 1 to the 3rd day every 24h, just stop taking the photograph sheet if more than 80% mark has disappeared from plain abdominal radiograph, otherwise every 24h took the photograph sheet 1 until the 7th day.The distribution of abdominal part mark is judged according to intestinal tube gas profile, lack clear profile person and then adopt the read tablet method of Arhan etc.: make line A (abdomen median line) from the 12nd spinous process of thoracic vertebra to the 5th spinous process of lumbar vertebra, again from fifth lumbar vertebra spinous process lower edge to the right inferior pelvic aperture make line B, and from fifth lumbar vertebra spinous process lower edge left anterior superior iliac spine make line C, total colectomy and anal orifice and rectal intestine are divided into right hemicolon district (RC), left hemicolon district (LC) and sigmoid colorectum district (SR) three regions, the mark quantity and distribution thereof that remain in intestinal are recorded in each film making, calculate the delay situation of each distinctive emblem thing.Calculate total colectomy by the time by Hinton method, each segmentation Colon absorption adopts Arhan method, and calculate with following formula CTT=1.2 ∑ ni, wherein i represents the natural law taking mark, and ni represents i-th day in the mark quantity of specifying section internal memory to stay.
Constipation group starts oral described Chinese medicine in the 2nd day after completing the 1st detection, each 1 bag, and every day 2 times, morning and evening 30min decoction being taken warmly after the meal, take 7 days continuously, period does not take any other medicine.The Colon absorption of each group of sample is as shown in the table:
The comparison of sample Colon absorption (h) respectively organized by table 1
| Group | Number of cases | Colon absorption |
| Healthy group | 20 | 33.5±14.8 |
| Before constipation group administration | 20 | 88.6±15.5 |
| After constipation group administration | 20 | 67.2±13.6 |
As can be seen from Table 1, the Colon absorption after the administration of constipation patient group has had obvious shortening before administration, shows that this Chinese medicine composition is significantly improved effect to functional constipation tool.
Claims (2)
1. be used for the treatment of a Chinese medicine composition for constipation, it is characterized in that, this Chinese medicine composition adopts following raw materials according medicine to combine: Cortex Magnoliae Officinalis, Semen Trichosanthis, Radix Glycyrrhizae and other material medicines.
2. Chinese medicine composition according to claim 1, it is characterized in that, this Chinese medicine composition is made up of according to weight proportion following raw materials according medicine: Radix Paeoniae Alba 10-15 part, Radix Asparagi 10-15 part, Cortex Magnoliae Officinalis 10-15 part, Semen Trichosanthis 10-15 part, Fructus Aurantii Immaturus 8-12 part, Radix Glycyrrhizae 5-9 part, Chalcanthitum 5-8 part, Radix Et Rhizoma Rhei 15-25 part, Rhizoma Alismatis 1-5 part, Radix Aucklandiae 6-15 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610098154.8A CN105535400A (en) | 2016-02-23 | 2016-02-23 | Traditional Chinese medicine composition for treating constipation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610098154.8A CN105535400A (en) | 2016-02-23 | 2016-02-23 | Traditional Chinese medicine composition for treating constipation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105535400A true CN105535400A (en) | 2016-05-04 |
Family
ID=55815310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610098154.8A Pending CN105535400A (en) | 2016-02-23 | 2016-02-23 | Traditional Chinese medicine composition for treating constipation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105535400A (en) |
-
2016
- 2016-02-23 CN CN201610098154.8A patent/CN105535400A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 狄玉敏等: "论"随其所得而攻之"", 《中国医药学报》 * |
| 陈南扬: "承气芍药甘草汤治疗肠梗阻98例", 《实用中医药杂志》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104338062A (en) | Chinese medicinal preparation for treating stomachache and diarrhea | |
| CN101797301B (en) | Medicine for preventing and curing middle and old aged constipation | |
| CN102357198B (en) | Chinese medicinal composition for treating constipation | |
| CN103405742B (en) | Drug composition for treating infantile diarrhea and preparation method thereof | |
| CN102357197B (en) | Traditional Chinese medicine composition for treating constipation | |
| CN102988591A (en) | Pure Chinese medicine preparation for treating astriction | |
| CN105832991A (en) | Traditional Chinese medicine composition for treating gastritis | |
| CN105456818A (en) | Traditional Chinese medicine composition containing folium artemisiae argyi and being capable of treating insomnia and preparation method of traditional Chinese medicine composition | |
| CN104721256A (en) | Anwei Yang extract as well as preparation method and medical application thereof | |
| CN103127480A (en) | Drug for curing constipation | |
| CN107260851B (en) | Traditional Chinese medicine composition for treating deficiency constipation | |
| CN105535400A (en) | Traditional Chinese medicine composition for treating constipation | |
| CN105456576A (en) | Traditional Chinese medicine composition for treating constipation | |
| CN104784650A (en) | Pharmaceutical preparation for clinical nursing of gastric ulcer | |
| CN104127787A (en) | Traditional Chinese medicinal plaster for treating constipations | |
| CN104013708A (en) | Traditional Chinese medicine composition for oral administration to treat irritable bowel syndrome | |
| CN103405574A (en) | Medicinal composition for treating hypertension | |
| CN103432502B (en) | A kind of Chinese patent medicine for the treatment of peptic ulcer disease | |
| CN103083459B (en) | Traditional Chinese medicinal compound preparation for treating constipation, and preparation method and application thereof | |
| CN100563685C (en) | A kind of Chinese patent medicine-Herba Cistanches relieving constipation preparation for the treatment of chronic constipation | |
| CN106728189B (en) | Traditional Chinese medicine for treating functional constipation of children and preparation method thereof | |
| CN102961680B (en) | Traditional Chinese medicine preparation for treating gallstone and cholecystitis and preparation method thereof | |
| CN104474512A (en) | Traditional Chinese medicine for treating hernia | |
| CN104510965A (en) | Traditional Chinese medicinal composition for treating child chronic gastritis | |
| CN104606427A (en) | Schefflera arboricola-contained traditional Chinese medicinal composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160504 |