CN105535398A - Compound ointment for treating facial acne and preparation method of compound ointment - Google Patents

Compound ointment for treating facial acne and preparation method of compound ointment Download PDF

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CN105535398A
CN105535398A CN201610029017.9A CN201610029017A CN105535398A CN 105535398 A CN105535398 A CN 105535398A CN 201610029017 A CN201610029017 A CN 201610029017A CN 105535398 A CN105535398 A CN 105535398A
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grams
gram
concentrated solution
ethanol
fructus
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李恒飞
冯大伟
金峰
杨帆
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Zhang Wupeng
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Abstract

The invention discloses a compound ointment for treating facial acne. The compound ointment comprises a composition A, a composition B, a composition C, a composition D and a composition E, wherein the composition A is prepared from the following raw materials: 15 g of selfheal, 1 g of jujube, 20 g of haw and 20 g of fructus corni; the composition B is prepared from the following raw materials: 16 g of scutellaria baicalensis, 5 g of viola tricolor, 5 g of cortex phellodendri, 2 g of potato, 0.8 g of cedarwood essential oil, 10 g of honeysuckle flower, 8 g of clove and 7 g of piper betle L.; the composition C is prepared from the following raw materials: 1 g of cochinchnese asparagus root, 6 g of honey, 4 g of rosemary essential oil, 1 g of damnacanthus indicus, 1 g of serissa japonica, 3 g of caltrop and 4 g of centella; the composition D is prepared from the following raw materials: 0.9 g of thyme, 6 g of tea tree, 1 g of lemon, 8 g of kadsura longipedunculata, 8 g of almond oil and 6 g of aloe; the composition E is prepared from the following raw materials: 5 g of dandelion, 3 g of rhizoma typhonii and 10 g of cape jasmine. The invention further discloses a preparation method of the compound ointment for treating facial acne.

Description

Composite medical ointment for the treatment of face comedo and preparation method thereof
Technical field
The invention belongs to field of Chinese herbal medicine technology, more specifically, the present invention relates to and a kind ofly treat composite medical ointment of face's comedo and preparation method thereof.
Background technology
Comedo is that a kind of chronic inflammatory skin of pilosebaceous unit is sick.The factors such as main and hypersteatosis, pilosebaceous duct block, bacteriological infection and inflammatory reaction are closely related.After adolescing, in human body, the level of androgen particularly testosterone raises rapidly, promotes that sebaceous gland is grown and produces a large amount of sebum.The dyskeratosis of pilosebaceous duct causes catheter blockage, dyssebacia simultaneously, forms horn plug and micropowder thorn.Multiple-microorganism especially propionibacterium acnes amount reproduction in hair follicle, the lipase decomposition sebum that propionibacterium acnes produces generates free fatty, chemotactic inflammatory cell and medium simultaneously, final induction also exacerbate inflammation reaction.
Present stage has the method for a lot of method removing acnes to have a lot, except some basic cleansing milk, elite breast, also has ointment, Chinese medicine etc.But these methods, have certain effect during use, but once stop using, just can recur again.Meanwhile, the product for resolving poxes of life-time service can produce certain Drug resistance, and outside life-time service, effect is very little, and after treatment, skin can exist the shortcoming such as cicatrix, corse sweat pore.
Summary of the invention
In order to solve the problem, one aspect of the present invention provides a kind of composite medical ointment for the treatment of face's comedo, comprises prescription A, prescription B, prescription C, prescription D and prescription E, wherein:
The raw materials of described prescription A is: Spica Prunellae 15 grams, Fructus Jujubae 1 gram, Fructus Crataegi 20 grams and Fructus Corni 20 grams;
The raw materials of described prescription B is: Radix Scutellariae 16 grams, Herba Violae Hortensis 5 grams, Chinese corktree 5 grams, 2 grams, Rhizoma Solani tuber osi, Cedrus deoclar (Roxb.) G. Don quintessence oil 0.8 gram, Flos Lonicerae 10 grams, Flos Caryophylli 8 grams and 7 grams, medicine beans leaf;
The raw materials of described prescription C is: Radix Asparagi 1 gram, Mel 6 grams, rosemary ethereal oil 4 grams, Herba Damnacanthi 1 gram, Serissa foetida 1 gram, Fructus Tribuli 3 grams and Herba Centellae 4 grams;
The raw materials of described prescription D is: Herba thymi vulgaris 0.9 gram, Camellia sinensis 6 grams, 1 gram, Fructus Citri Limoniae, Radix Kadsurae longipedunculatae 8 grams, almond oil 8 grams, Aloe 6 grams;
The raw materials of described prescription E is: Herba crotalariae albidae 5 grams, Rhizoma Typhonii 3 grams and Fructus Gardeniae 10 grams.
Another aspect of the present invention provides the preparation method of the composite medical ointment for the treatment of face comedo, comprises the following steps:
(1) Spica Prunellae 15 grams, Fructus Jujubae 1 gram, Fructus Crataegi 20 grams and Fructus Corni 20 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 12 hours, distilling under reduced pressure remove ethanol and concentrated solution F;
(2) by Radix Scutellariae 16 grams, Herba Violae Hortensis 5 grams, Chinese corktree 5 grams, 2 grams, Rhizoma Solani tuber osi, Cedrus deoclar (Roxb.) G. Don quintessence oil 0.8 gram, Flos Lonicerae 10 grams, Flos Caryophylli 8 grams and 7 grams, medicine beans leaf clean, chopping and with filter paper parcel after, in ethanol, surname extraction is after 24 hours, and distilling under reduced pressure is removed ethanol and obtained concentrated solution G;
(3) by Radix Asparagi 1 gram, Mel 6 grams, rosemary ethereal oil 4 grams, Herba Damnacanthi 1 gram, Serissa foetida 1 gram, Fructus Tribuli 3 grams and Herba Centellae 4 grams clean, chopping and with filter paper parcel after, in ethanol, surname extraction is after 10 hours, and distilling under reduced pressure is removed ethanol and obtained concentrated solution H;
(4) Herba thymi vulgaris 0.9 gram, Camellia sinensis 6 grams, 1 gram, Fructus Citri Limoniae, Radix Kadsurae longipedunculatae 8 grams, almond oil 8 grams, Aloe 6 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 48 hours, distilling under reduced pressure remove ethanol and concentrated solution I;
(5) Herba crotalariae albidae 5 grams, Rhizoma Typhonii 3 grams and Fructus Gardeniae 10 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 30 hours, distilling under reduced pressure remove ethanol and concentrated solution J;
(6) after concentrated solution F, concentrated solution G, concentrated solution H and concentrated solution I fully being mixed, add 0.1 gram of beta-schardinger dextrin-, 10ml ethanol and 100 grams of distilled water, mechanical agitation is after 20 minutes, add concentrated solution J again, and be heated to 40 DEG C, keep after 1 hour, be cooled to room temperature and obtain medical treatment the composite medical ointment of face's comedo.
Be easier to understand the above-mentioned of the application and other features, aspect and advantage with reference to following detailed description.
Detailed description of the invention
Below by embodiment, the present invention is specifically described.What be necessary to herein means out is; following examples are only for the invention will be further described; limiting the scope of the invention can not be interpreted as; some nonessential improvement and adjustment that the professional and technical personnel in this field makes according to the content of the invention described above, still belong to protection scope of the present invention.
One aspect of the present invention provides a kind of composite medical ointment for the treatment of face's comedo, comprises prescription A, prescription B, prescription C, prescription D and prescription E, wherein:
The raw materials of described prescription A is: Spica Prunellae 15 grams, Fructus Jujubae 1 gram, Fructus Crataegi 20 grams and Fructus Corni 20 grams;
The raw materials of described prescription B is: Radix Scutellariae 16 grams, Herba Violae Hortensis 5 grams, Chinese corktree 5 grams, 2 grams, Rhizoma Solani tuber osi, Cedrus deoclar (Roxb.) G. Don quintessence oil 0.8 gram, Flos Lonicerae 10 grams, Flos Caryophylli 8 grams and 7 grams, medicine beans leaf;
The raw materials of described prescription C is: Radix Asparagi 1 gram, Mel 6 grams, rosemary ethereal oil 4 grams, Herba Damnacanthi 1 gram, Serissa foetida 1 gram, Fructus Tribuli 3 grams and Herba Centellae 4 grams;
The raw materials of described prescription D is: Herba thymi vulgaris 0.9 gram, Camellia sinensis 6 grams, 1 gram, Fructus Citri Limoniae, Radix Kadsurae longipedunculatae 8 grams, almond oil 8 grams, Aloe 6 grams;
The raw materials of described prescription E is: Herba crotalariae albidae 5 grams, Rhizoma Typhonii 3 grams and Fructus Gardeniae 10 grams.
In above-mentioned medicament, the drug effect of various composition describes as follows:
Spica Prunellae has the effect of invigorating blood circulation; Fructus Jujubae sweet in the mouth is warm in nature, return taste warp, has the function of invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, the mitigation property of medicine; Fructus Crataegi is warm in nature, sweet in the mouth, acid, returns spleen, stomach, Liver Channel, has promoting digestion and invigorating the stomach, and circulation of qi promoting dissipating blood stasis changes effect of turbid blood fat reducing; Fructus Corni sour in the mouth, puckery, slightly warm in nature, returns liver, kidney channel, liver and kidney tonifying, and convergence is solid de-; Radix Scutellariae washout wound, has antisepsis; Herba Violae Hortensis can sterilize, comedo, acne, allergic problem on treatment skin; Chinese corktree bitter in the mouth, cold in nature.Return kidney, urinary bladder channel; The antimicrobial component that Rhizoma Solani tuber osi contains helps preventing gastric ulcer, and it not only has antibacterial effect effect, can not cause Drug resistance simultaneously; Cedrus deoclar (Roxb.) G. Don quintessence oil has significant antiinflammatory, antibacterial, convergence, diuresis, softness, reduce phlegm, the effect of antifungal, benefit body, convergence, antibacterial characteristic are conducive to oiliness skin quality most, also can improve pimples and acne-prone skin; Flos Lonicerae has antibacterial, antiinflammation; Flos Caryophylli has inhibitory action for pathogenic fungus and staphylococcus, dysentery and escherichia coli etc., also can do external; Medicine beans leaf dispeiling pathogenic wind and removing dampness, killing parasites for relieving itching; Radix Asparagi is controlled asthenia and is hindered absolutely, decline old age damage win thin, hemiplegia not with, rheumatism is meciless, cold numbness, and trusted subordinate gathers, malignant boil, and carbuncle swells leprosy, also controls impotence, deafness, order are dark; Mel heat clearing away, invigorating middle warmer, moisturizes analgesic antidotal beauty treatment; Rosemary ethereal oil has potent convergence, and consolidation is lost weight, wrinkle resistant, regulates the effect of cortex, nurses one's health greasy unclean skin, blood circulation promoting; Herba Damnacanthi inducing diuresis to remove edema, promoting blood circulation to remove blood stasis; Serissa foetida is light, micro-pungent, cool; Fructus Tribuli suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus; Herba Centellae clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating; Herba thymi vulgaris acrid in the mouth, warm in nature; Camellia sinensis is bitter, flat; Fructus Citri Limoniae is containing compositions such as vitamin B1, B2, C, Yan acid, saccharide, calcium, phosphorus, ferrum; Radix Kadsurae longipedunculatae circulation of qi promoting, invigorates blood circulation, pain relieving; Almond oil effectively can alleviate the skin people and to itch phenomenon, eliminates red and swollen, dry and inflammation, can stimulate the sagging gland of the brain of hormonal system, thymus and adrenal gland, promote cell turnover; Aloe has eliminating fire and detoxication, effect of blood stasis dispelling parasite killing; Herba crotalariae albidae heat-clearing and toxic substances removing; Rhizoma Typhonii dispels the wind expectorant, and arresting convulsion is jerked, detoxicating and resolving stagnation of pathogens, pain relieving; Fructus Gardeniae has sterilization, aging-resistant effect.
Another aspect of the present invention provides the preparation method of the composite medical ointment for the treatment of face comedo, comprises the following steps:
(1) Spica Prunellae 15 grams, Fructus Jujubae 1 gram, Fructus Crataegi 20 grams and Fructus Corni 20 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 12 hours, distilling under reduced pressure remove ethanol and concentrated solution F;
(2) by Radix Scutellariae 16 grams, Herba Violae Hortensis 5 grams, Chinese corktree 5 grams, 2 grams, Rhizoma Solani tuber osi, Cedrus deoclar (Roxb.) G. Don quintessence oil 0.8 gram, Flos Lonicerae 10 grams, Flos Caryophylli 8 grams and 7 grams, medicine beans leaf clean, chopping and with filter paper parcel after, in ethanol, surname extraction is after 24 hours, and distilling under reduced pressure is removed ethanol and obtained concentrated solution G;
(3) by Radix Asparagi 1 gram, Mel 6 grams, rosemary ethereal oil 4 grams, Herba Damnacanthi 1 gram, Serissa foetida 1 gram, Fructus Tribuli 3 grams and Herba Centellae 4 grams clean, chopping and with filter paper parcel after, in ethanol, surname extraction is after 10 hours, and distilling under reduced pressure is removed ethanol and obtained concentrated solution H;
(4) Herba thymi vulgaris 0.9 gram, Camellia sinensis 6 grams, 1 gram, Fructus Citri Limoniae, Radix Kadsurae longipedunculatae 8 grams, almond oil 8 grams, Aloe 6 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 48 hours, distilling under reduced pressure remove ethanol and concentrated solution I;
(5) Herba crotalariae albidae 5 grams, Rhizoma Typhonii 3 grams and Fructus Gardeniae 10 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 30 hours, distilling under reduced pressure remove ethanol and concentrated solution J;
(6) after concentrated solution F, concentrated solution G, concentrated solution H and concentrated solution I fully being mixed, add 0.1 gram of beta-schardinger dextrin-, 10ml ethanol and 100 grams of distilled water, mechanical agitation is after 20 minutes, add concentrated solution J again, and be heated to 40 DEG C, keep after 1 hour, be cooled to room temperature and obtain medical treatment the composite medical ointment of face's comedo.
The good essence of the compatibility can be obtained by the extraction of ethanol, and by the method extracted respectively and add beta-schardinger dextrin-and can play drug effect better, obtain better synergy, thus provide Advantageous Effects of the present invention.
Detailed description of the invention comprises:
Embodiment 1
(1) Spica Prunellae 15 grams, Fructus Jujubae 1 gram, Fructus Crataegi 20 grams and Fructus Corni 20 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 12 hours, distilling under reduced pressure remove ethanol and concentrated solution F;
(2) by Radix Scutellariae 16 grams, Herba Violae Hortensis 5 grams, Chinese corktree 5 grams, 2 grams, Rhizoma Solani tuber osi, Cedrus deoclar (Roxb.) G. Don quintessence oil 0.8 gram, Flos Lonicerae 10 grams, Flos Caryophylli 8 grams and 7 grams, medicine beans leaf clean, chopping and with filter paper parcel after, in ethanol, surname extraction is after 24 hours, and distilling under reduced pressure is removed ethanol and obtained concentrated solution G;
(3) by Radix Asparagi 1 gram, Mel 6 grams, rosemary ethereal oil 4 grams, Herba Damnacanthi 1 gram, Serissa foetida 1 gram, Fructus Tribuli 3 grams and Herba Centellae 4 grams clean, chopping and with filter paper parcel after, in ethanol, surname extraction is after 10 hours, and distilling under reduced pressure is removed ethanol and obtained concentrated solution H;
(4) Herba thymi vulgaris 0.9 gram, Camellia sinensis 6 grams, 1 gram, Fructus Citri Limoniae, Radix Kadsurae longipedunculatae 8 grams, almond oil 8 grams, Aloe 6 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 48 hours, distilling under reduced pressure remove ethanol and concentrated solution I;
(5) Herba crotalariae albidae 5 grams, Rhizoma Typhonii 3 grams and Fructus Gardeniae 10 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 30 hours, distilling under reduced pressure remove ethanol and concentrated solution J;
(6) after concentrated solution F, concentrated solution G, concentrated solution H and concentrated solution I fully being mixed, add 0.1 gram of beta-schardinger dextrin-, 10ml ethanol and 100 grams of distilled water, mechanical agitation is after 20 minutes, add concentrated solution J again, and be heated to 40 DEG C, keep after 1 hour, be cooled to room temperature and obtain medical treatment the composite medical ointment of face's comedo.
Comparative example 1
Similar with the embodiment of embodiment 1, difference is that step (1) material used is:
Spica Prunellae 10 grams, Fructus Jujubae 2 grams, Fructus Crataegi 10 grams and Fructus Corni 10 grams.
Comparative example 2
Similar with the embodiment of embodiment 1, difference is that step (2) material used is:
Radix Scutellariae 13 grams, Herba Violae Hortensis 10 grams, Chinese corktree 8 grams, 1 gram, Rhizoma Solani tuber osi, Cedrus deoclar (Roxb.) G. Don quintessence oil 1 gram, Flos Lonicerae 10 grams, Flos Caryophylli 8 grams and 7 grams, medicine beans leaf.
Comparative example 3
Similar with the embodiment of embodiment 1, difference is that step (3) material used is:
Radix Asparagi 2 grams, Mel 5 grams, rosemary ethereal oil 3 grams, Herba Damnacanthi 2 grams, Serissa foetida 2 grams, Fructus Tribuli 2 grams and Herba Centellae 1 gram.
Comparative example 4
Similar with the embodiment of embodiment 1, difference is that step (4) material used is:
Herba thymi vulgaris 1 gram, Camellia sinensis 5 grams, 2 grams, Fructus Citri Limoniae, Radix Kadsurae longipedunculatae 8 grams, almond oil 8 grams, Aloe 6 grams.
Comparative example 5
Similar with the embodiment of embodiment 1, difference is that step (5) material used is:
Herba crotalariae albidae 8 grams, Rhizoma Typhonii 1 gram and Fructus Gardeniae 5 grams.
Comparative example 6
Similar with the embodiment of embodiment 1, difference is not containing implementation step (5) and does not contain concentrated solution J.
Comparative example 7
Similar with the embodiment of embodiment 1, difference is concentrated solution J and concentrated solution F, concentrated solution G, concentrated solution H and concentrated solution I to be mixed together in step (6), does not prepare in two steps.
evaluation methodology:
Select 400 volunteers of age between 18-30 year, each group Stochastic choice 50 patients carry out clinical trial.Morning, noon and afternoon every day respectively use once, continuously uninterrupted use 60 days.
Opinion rating is divided into A, and comedo disappears completely; B, comedo alleviates about 70%; C, comedo alleviates about 50%; D, comedo does not change.
Curative effect is in table 1:
Table 1
As can be seen from Table 1, achieve better synergism with specific ratio conbined usage by specific preparation method by different Chinese medicinal components, effectively can treat comedo, reach unexpected technique effect.
Aforesaid example is only illustrative, for explaining some features of feature of the present disclosure.Appended claim is intended to the scope wide as far as possible that requirement it is contemplated that, and the embodiment presented herein is only the explanation of the embodiment of the selection of combination according to all possible embodiment.Therefore, the purpose of applicant is the selectional restriction that appended claim is not illustrated the example of feature of the present invention.And progress in science and technology is not replaced to be formed due to the inaccurate reason of language performance by the possible equivalent considered at present or son, and these changes also should be interpreted as being covered by appended claim in the conceived case.

Claims (2)

1. treat the composite medical ointment of face's comedo, comprise prescription A, prescription B, prescription C, prescription D and prescription E, wherein:
The raw materials of described prescription A is: Spica Prunellae 15 grams, Fructus Jujubae 1 gram, Fructus Crataegi 20 grams and Fructus Corni 20 grams;
The raw materials of described prescription B is: Radix Scutellariae 16 grams, Herba Violae Hortensis 5 grams, Chinese corktree 5 grams, 2 grams, Rhizoma Solani tuber osi, Cedrus deoclar (Roxb.) G. Don quintessence oil 0.8 gram, Flos Lonicerae 10 grams, Flos Caryophylli 8 grams and 7 grams, medicine beans leaf;
The raw materials of described prescription C is: Radix Asparagi 1 gram, Mel 6 grams, rosemary ethereal oil 4 grams, Herba Damnacanthi 1 gram, Serissa foetida 1 gram, Fructus Tribuli 3 grams and Herba Centellae 4 grams;
The raw materials of described prescription D is: Herba thymi vulgaris 0.9 gram, Camellia sinensis 6 grams, 1 gram, Fructus Citri Limoniae, Radix Kadsurae longipedunculatae 8 grams, almond oil 8 grams, Aloe 6 grams;
The raw materials of described prescription E is: Herba crotalariae albidae 5 grams, Rhizoma Typhonii 3 grams and Fructus Gardeniae 10 grams.
2. treat the preparation method of the composite medical ointment of face's comedo, comprise the following steps:
(1) Spica Prunellae 15 grams, Fructus Jujubae 1 gram, Fructus Crataegi 20 grams and Fructus Corni 20 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 12 hours, distilling under reduced pressure remove ethanol and concentrated solution F;
(2) by Radix Scutellariae 16 grams, Herba Violae Hortensis 5 grams, Chinese corktree 5 grams, 2 grams, Rhizoma Solani tuber osi, Cedrus deoclar (Roxb.) G. Don quintessence oil 0.8 gram, Flos Lonicerae 10 grams, Flos Caryophylli 8 grams and 7 grams, medicine beans leaf clean, chopping and with filter paper parcel after, in ethanol, surname extraction is after 24 hours, and distilling under reduced pressure is removed ethanol and obtained concentrated solution G;
(3) by Radix Asparagi 1 gram, Mel 6 grams, rosemary ethereal oil 4 grams, Herba Damnacanthi 1 gram, Serissa foetida 1 gram, Fructus Tribuli 3 grams and Herba Centellae 4 grams clean, chopping and with filter paper parcel after, in ethanol, surname extraction is after 10 hours, and distilling under reduced pressure is removed ethanol and obtained concentrated solution H;
(4) Herba thymi vulgaris 0.9 gram, Camellia sinensis 6 grams, 1 gram, Fructus Citri Limoniae, Radix Kadsurae longipedunculatae 8 grams, almond oil 8 grams, Aloe 6 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 48 hours, distilling under reduced pressure remove ethanol and concentrated solution I;
(5) Herba crotalariae albidae 5 grams, Rhizoma Typhonii 3 grams and Fructus Gardeniae 10 grams are cleaned, chopping with after filter paper parcel, in ethanol, surname extraction is after 30 hours, distilling under reduced pressure remove ethanol and concentrated solution J;
(6) after concentrated solution F, concentrated solution G, concentrated solution H and concentrated solution I fully being mixed, add 0.1 gram of beta-schardinger dextrin-, 10ml ethanol and 100 grams of distilled water, mechanical agitation is after 20 minutes, add concentrated solution J again, and be heated to 40 DEG C, keep after 1 hour, be cooled to room temperature and obtain medical treatment the composite medical ointment of face's comedo.
CN201610029017.9A 2016-01-15 2016-01-15 Compound ointment for treating facial acne and preparation method of compound ointment Pending CN105535398A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103041243A (en) * 2013-01-29 2013-04-17 宋小冰 Traditional Chinese medicine capsule for clearing heat, expelling noxious substances and removing acnes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103041243A (en) * 2013-01-29 2013-04-17 宋小冰 Traditional Chinese medicine capsule for clearing heat, expelling noxious substances and removing acnes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘学义等: "滋阴消痤汤治疗痤疮189例", 《新中医》 *
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