CN105527415A - Fast detection device and method for blood physical signs - Google Patents
Fast detection device and method for blood physical signs Download PDFInfo
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- CN105527415A CN105527415A CN201610026869.2A CN201610026869A CN105527415A CN 105527415 A CN105527415 A CN 105527415A CN 201610026869 A CN201610026869 A CN 201610026869A CN 105527415 A CN105527415 A CN 105527415A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
- G01N33/48771—Coding of information, e.g. calibration data, lot number
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
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- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Abstract
The invention relates to a fast detection device and method for blood physical signs. At present, a device for blood physical signs is mostly photoelectric, and has defects that a probe is easily polluted when exposed in air, a surrounding environment easily affects a test result and a service life is shorter. The device comprises a base layer, wherein multiple conductive strips are distributed at the top surface of the base layer and comprise a first electrode, a second electrode, a third electrode, a fourth electrode, a test paper identity recognition electrode, and a first separating rubber layer covering the conductive strips; a top plate layer is arranged at the top surface of the separating rubber layer; ends of the conductive strips can accept detection of an external matched instrument, reaction regions are arranged at the other ends of the conductive strips and comprise a reaction substance and four correlated electrodes. The aim of measuring different blood physical signs by one instrument is achieved, so that the function of the instrument is powerful, an operation manner is simpler and air pollution in a detection environment is avoided.
Description
Technical field
The present invention relates to a kind of blood test device, specifically a kind of rapid blood physical signs pick-up unit and detection method.
Background technology
Carry out the device of Blood Physiological Indexes analysis at present, mostly adopt photoelectric type, the shortcoming of this device is that detecting head is exposed in air and is easy to be polluted, and surrounding environment easily affects test result, and serviceable life is shorter; When carrying out Blood Physiological Indexes analysis at present, different physical signs needs to use different test test pieces and different instruments, and in addition, tester's operation technique is incorrect also can affect test effect, needs operator's sets itself and adjustment proving installation in operating process.
Summary of the invention
Technical assignment of the present invention is for above deficiency, a kind of quick multiple Blood Physiological Indexes pick-up unit and detection method are provided, solve same instrument to be difficult to measure different Blood Physiological Indexes, need debug voluntarily when carrying out Blood Physiological Indexes and detecting, and the problem of test less effective.
Technical assignment of the present invention realizes by following technical scheme,
Rapid blood physical signs pick-up unit, comprise basic unit, many buss are laid in substrate top surface, bus is the first electrode respectively, second electrode, 3rd electrode, 4th electrode and test paper identification electrode, and cover the first glue partiting layer of described bus, and the first glue partiting layer end face lays a top board layer, described bus one end can connect extraneous necessary instrument, the other end is provided with reaction zone, this reaction zone comprises reactive material and four associated electrodes, four associated electrodes are respectively the first associated electrodes, second associated electrodes, 3rd associated electrodes, 4th associated electrodes, this first glue partiting layer forms groove portion relative to the position of reaction zone, this groove portion forms the notch that the extraneous blood of supply infiltrates reaction zone in basic unit edge, this first glue partiting layer also has the air drain in connectivity slot portion, this air drain forms blow vent in another edge of basic unit, this air drain and air communication, and then by siphon mode by blood sucting reaction district.
Described reactive material is can reactant chemicals, solves the problem of the different Blood Physiological Indexes of same apparatus measures.
The detection method of described rapid blood physical signs pick-up unit is, when a sample corpse or other object for laboratory examination and chemical testing contacts the first electrode and the second electrode, transmits first signal to extraneous necessary instrument; Blood sample transmits raw second signal to extraneous necessary instrument when arriving the 4th electrode, extraneous necessary instrument can the flowing time of a computing sample corpse or other object for laboratory examination and chemical testing by interval time of measurement two signals, and then the analyte concentration of a sample corpse or other object for laboratory examination and chemical testing can be obtained, and can by flowing time correction analysis substrate concentration, thus make the physiological data of measurement more accurate.When blood is through the 3rd electrode, instrument starts to measure, and preventing to suck blood not enoughly affects measurement result; When blood flows through reaction zone, the reactive material of meeting and reaction zone produces reaction, produces a current signal special delivery to extraneous necessary instrument, and extraneous necessary instrument passes through the power of detection electric current and then calculates desired Blood Physiological Indexes; And corrected the concentration of the analyte of interest of blood by the flow velocity measuring blood, and then obtain physical signs more accurately.
Described extraneous necessary instrument is rapid blood physical signs tester, this device and rapid blood physical signs pick-up unit with the use of, the Blood Physiological Indexes corresponding according to the input of rapid blood physical signs pick-up unit transmission. at present, on market, existing rapid blood physical signs tester is as blood-sugar detecting instrument, the registration certificate produced by thick virtue bio tech ltd, manufacturer Qingdao is numbered 20152400303, production model and specification are AC-300, AC-301, the detecting instruments such as AC-302, blood sugar can be carried out respectively, blood ketone, uric acid, the detection of the different physical signs such as triglyceride.
Test paper identification electrode of the present invention is made up of multiple electrodes that four are connected by circuit, by cutting off the associated electronic circuitry of each electrode, and then be combined into different discriminators, necessary instrument is by identifying that different electrode combination classification identifies the identity of test pieces, and then make the reflection meeting this test pieces, thus reach can by the object of the different Blood Physiological Indexes of same apparatus measures and various trait test pieces, thus make the with better function of instrument, and mode of operation is simpler, the pollution being subject to air in testing environment can be avoided simultaneously.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the present invention is further described.
Accompanying drawing 1 is rapid blood physical signs pick-up unit glue partiting layer place structural representation;
Accompanying drawing 2 is the one-piece construction schematic diagram of rapid blood physical signs pick-up unit;
Accompanying drawing 3 is the structural representation of rapid blood physical signs pick-up unit electrode;
Accompanying drawing 4 is the side schematic view at rapid blood physical signs pick-up unit notch place;
Accompanying drawing 5 is the front schematic view at rapid blood physical signs pick-up unit air drain place;
In figure: 1: basic unit; 2: bus; 3: glue partiting layer; 4: top board layer; 5: reaction zone; 6: groove portion;
7: the first associated electrodes; 8 second associated electrodes: 9: the three associated electrodes; 10: the four associated electrodes;
11: test paper identification electrode; 12: the first electrodes; 13: the second electrodes; 14 the 3rd electrodes; 15: the four electrodes; 16: notch; 17: air drain.
Embodiment
With reference to Figure of description and specific embodiment, rapid blood physical signs pick-up unit of the present invention and detection method are described in detail below.
Rapid blood physical signs pick-up unit, comprise basic unit, lay many circuit in substrate top surface and connect multiple electrode, they are the first electrode respectively, second electrode, 3rd electrode, 4th electrode and test paper identification electrode, and cover the first glue partiting layer of described bus, and the first glue partiting layer end face lays a chemical reaction zone, described bus one end can accept extraneous instrument and detect, other end coupled reaction district, this reaction zone comprises biology enzyme and the first electrode, second electrode, 3rd electrode, 4th electrode, this first glue partiting layer forms groove portion relative to the position of reaction zone, this groove portion forms the notch in the extraneous blood sucting reaction district of supply in limit, basic unit one end, this first glue partiting layer also has the air drain in a connectivity slot portion, this air drain forms blow vent in basic unit's other end limit, this air drain is by described notch, air drain is communicated with air with blow vent, and be beneficial to blood by siphon mode sucting reaction district.
Rapid blood physical signs pick-up unit, its detection method is, when a sample corpse or other object for laboratory examination and chemical testing contacts the first electrode and the second electrode, transmits first signal to necessary instrument; A corpse or other object for laboratory examination and chemical testing transmits raw second signal to necessary instrument when arriving the 4th electrode, for the flowing time of a computing sample corpse or other object for laboratory examination and chemical testing, the analyte concentration of a sample corpse or other object for laboratory examination and chemical testing can be obtained, and can by flowing time correction analysis substrate concentration, and then the number making necessary instrument can produce material further by the concentration corrected in blood when being detected Blood Physiological Indexes by electrochemical process go to correct the physical signs recorded, and then make the physical signs that records more accurate.But also the characteristic of the test paper inserting necessary instrument can be identified by test paper identification electrode, thus make instrument automatically can make according to the test paper characteristic identified the reflection matched.
By embodiment above, described those skilled in the art can be easy to realize the present invention.But should be appreciated that the present invention is not limited to above-mentioned embodiment.On the basis of disclosed embodiment, described those skilled in the art can the different technical characteristic of combination in any, thus realizes different technical schemes.
Except the technical characteristic described in instructions, be the known technology of those skilled in the art.
Claims (4)
1. rapid blood physical signs pick-up unit, comprise basic unit, many buss are laid in substrate top surface, bus is the first electrode respectively, second electrode, 3rd electrode, 4th electrode and test paper identification electrode, and cover the first glue partiting layer of described bus, and the first glue partiting layer end face lays a top board layer, described bus one end can connect extraneous necessary instrument, the other end is provided with reaction zone, this reaction zone comprises reactive material and four associated electrodes, four associated electrodes are respectively the first associated electrodes, second associated electrodes, 3rd associated electrodes, 4th associated electrodes, this first glue partiting layer forms groove portion relative to the position of reaction zone, this groove portion forms the notch that the extraneous blood of supply infiltrates reaction zone in basic unit edge, this first glue partiting layer also has the air drain in connectivity slot portion, this air drain forms blow vent in another edge of basic unit, this air drain and air communication, and then by siphon mode by blood sucting reaction district.
2. rapid blood physical signs pick-up unit according to claim 1, is characterized in that, described reactive material is can reactant chemicals, solves the problem of the different Blood Physiological Indexes of same apparatus measures.
3. rapid blood physical signs pick-up unit according to claim 1, it is characterized in that, described extraneous necessary instrument is rapid blood physical signs tester, this device and rapid blood physical signs pick-up unit are with the use of, the Blood Physiological Indexes that the input transmitted according to rapid blood physical signs pick-up unit is corresponding.
4. described in, the detection method of rapid blood physical signs pick-up unit is, when a sample corpse or other object for laboratory examination and chemical testing contacts the first electrode and the second electrode, transmits first signal to extraneous necessary instrument; Blood sample transmits raw second signal to extraneous necessary instrument when arriving the 4th electrode, extraneous necessary instrument can the flowing time of a computing sample corpse or other object for laboratory examination and chemical testing by interval time of measurement two signals, and then the analyte concentration of a sample corpse or other object for laboratory examination and chemical testing can be obtained, and can by flowing time correction analysis substrate concentration, thus make the physiological data of measurement more accurate, when blood is through the 3rd electrode, instrument starts to measure, and preventing to suck blood not enoughly affects measurement result; When blood flows through reaction zone, the reactive material of meeting and reaction zone produces reaction, produces a current signal special delivery to extraneous necessary instrument, and extraneous necessary instrument passes through the power of detection electric current and then calculates desired Blood Physiological Indexes; And corrected the concentration of the analyte of interest of blood by the flow velocity measuring blood, and then obtain physical signs more accurately.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610026869.2A CN105527415A (en) | 2016-01-17 | 2016-01-17 | Fast detection device and method for blood physical signs |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610026869.2A CN105527415A (en) | 2016-01-17 | 2016-01-17 | Fast detection device and method for blood physical signs |
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| CN105527415A true CN105527415A (en) | 2016-04-27 |
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| CN201610026869.2A Pending CN105527415A (en) | 2016-01-17 | 2016-01-17 | Fast detection device and method for blood physical signs |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109142484A (en) * | 2018-07-23 | 2019-01-04 | 青岛厚美德生物科技有限公司 | A kind of parameter recognition component and exempt from bar code bio-sensing test paper |
| CN109541196A (en) * | 2018-12-20 | 2019-03-29 | 广州南雪医疗器械有限公司 | A kind of blood testing test paper |
| CN110927085A (en) * | 2019-12-13 | 2020-03-27 | 循证医疗科技(杭州)有限公司 | Blood sample detection system |
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| US6743635B2 (en) * | 2002-04-25 | 2004-06-01 | Home Diagnostics, Inc. | System and methods for blood glucose sensing |
| CN101430327A (en) * | 2007-11-08 | 2009-05-13 | 厚美德生物科技股份有限公司 | Detection test piece with recognition function and its detection apparatus |
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| WO2014207152A1 (en) * | 2013-06-27 | 2014-12-31 | Lifescan Scotland Limited | Fill error trap for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte |
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2016
- 2016-01-17 CN CN201610026869.2A patent/CN105527415A/en active Pending
Patent Citations (9)
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| US5650062A (en) * | 1995-03-17 | 1997-07-22 | Matsushita Electric Industrial Co., Ltd. | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same |
| US6743635B2 (en) * | 2002-04-25 | 2004-06-01 | Home Diagnostics, Inc. | System and methods for blood glucose sensing |
| CN101430327A (en) * | 2007-11-08 | 2009-05-13 | 厚美德生物科技股份有限公司 | Detection test piece with recognition function and its detection apparatus |
| CN102147390A (en) * | 2009-12-18 | 2011-08-10 | 五鼎生物技术股份有限公司 | Electrochemical test strip, electrochemical test system, and measurement method using the same |
| CN103732135A (en) * | 2011-08-19 | 2014-04-16 | 株式会社村田制作所 | Living organism sensor |
| CN202562878U (en) * | 2012-03-07 | 2012-11-28 | 陈沅堃 | Test sheet structure |
| CN102967637A (en) * | 2012-03-31 | 2013-03-13 | 艾康生物技术(杭州)有限公司 | Automatic coding device and biosensor with the same |
| WO2014207152A1 (en) * | 2013-06-27 | 2014-12-31 | Lifescan Scotland Limited | Fill error trap for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109142484A (en) * | 2018-07-23 | 2019-01-04 | 青岛厚美德生物科技有限公司 | A kind of parameter recognition component and exempt from bar code bio-sensing test paper |
| CN109541196A (en) * | 2018-12-20 | 2019-03-29 | 广州南雪医疗器械有限公司 | A kind of blood testing test paper |
| CN110927085A (en) * | 2019-12-13 | 2020-03-27 | 循证医疗科技(杭州)有限公司 | Blood sample detection system |
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Application publication date: 20160427 |
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