CN209148584U - A kind of electrochemical sensor electrodes test piece of multi-parameter detection - Google Patents

A kind of electrochemical sensor electrodes test piece of multi-parameter detection Download PDF

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Publication number
CN209148584U
CN209148584U CN201821421743.6U CN201821421743U CN209148584U CN 209148584 U CN209148584 U CN 209148584U CN 201821421743 U CN201821421743 U CN 201821421743U CN 209148584 U CN209148584 U CN 209148584U
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electrode
test piece
substrate
sensor electrodes
electrochemical sensor
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CN201821421743.6U
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梁波
叶学松
赵欢萍
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Shandong Industrial Technology Research Institute of ZJU
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Shandong Industrial Technology Research Institute of ZJU
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Abstract

The utility model discloses a kind of electrochemical sensor electrodes test piece of multi-parameter detection, including substrate and electrode group, electrode group includes at least working electrode and auxiliary electrode, is respectively provided with an electrode group in the opposite both ends of the surface of substrate.The utility model, which provides one kind, can be carried out multi-parameter detection, improve the electrochemical sensor electrodes test piece of the utilization rate of electrode test piece.

Description

A kind of electrochemical sensor electrodes test piece of multi-parameter detection
Technical field
The utility model relates to electrochemical fields, more specifically, it is related to a kind of electrochemical sensing of multi-parameter detection Device electrode test piece.
Background technique
It is widely used using electrochemica biological sensor as the electrochemical test bar of principle in detection field (POCT) immediately.It is raw It manages liquid such as blood, urine, sweat, contain the interested detection parameters of many clinical labororatories in saliva, such as in blood Glucose, cholesterol, glycosylated hemoglobin, blood ketone, the uric acid in urine, the lactic acid etc. in sweat.And these detection parameters have There is the demand often detected.Currently, only one most reaction chamber of common commercialization electrochemical test bar, and measure every time only One-component can be detected.One bleed or one drop sample to be tested liquid can only detect a kind of parameter.
Summary of the invention
The purpose of this utility model is to provide one kind can be carried out multi-parameter detection, improves the electricity of the utilization rate of electrode test piece Chemical sensor electrode test piece.
The technical scheme adopted by the utility model to solve the technical problem is as follows: a kind of electrochemical sensing of multi-parameter detection Device electrode test piece, including substrate and electrode group, electrode group include at least working electrode and auxiliary electrode, the opposite both ends of the surface of substrate On be respectively provided with an electrode group.
As a preferred option, substrate two sides are respectively provided with an electrode group.
As a preferred option, in the opposite both ends of the surface of substrate and two sides are respectively provided with a recognition terminal, identify end Son is between working electrode and auxiliary electrode.
As a preferred option, each electrode group also has reference electrode.Working electrode and auxiliary electrode formation detect back Road generates electric current and captures the concentration that electric signal is converted into sample to be tested again.Working electrode and reference electrode constitute one it is obstructed or Substantially the system being powered less measures the electrode potential of working electrode using the stability of reference electrode current potential.Preferably, electric grade Group further includes detecting electrode.Detecting electrode has short-circuit self-checking function or is loaded insufficient detection function, if detecting electrode has When short-circuit self-checking function, i.e., when test strips are inserted into detector, it is short for judging if the test paper is used or short-circuit Road can not continue to use.If detecting electrode has sample-adding deficiency detection function, when the sample to be tested that test strips are added is insufficient When, instrument can then show that sample-adding amount deficiency need to mend additional sample to be tested amount at the appointed time and can accurately test.The electrification Learning sensor electrode test piece can be in response to the different number of electrode of electrochemical action demand difference collocation.
As a preferred option, electrode group has electrode terminal, conducting part and a reacting part, electrode terminal, conducting part and anti- Portion is answered to be sequentially connected.
As a preferred option, the reacting part of working electrode and auxiliary electrode is bent in opposite directions.
As a preferred option, substrate two sides are respectively provided with detection slot, and reactive site is in detection slot and exposing to detection Slot.
As a preferred option, the both ends of the surface of the substrate and two sides are equipped with siphon cover board.
Utility model has the advantages that
1, by the way that electrode group is arranged in the front and back sides of substrate, the working electrode in electrode group can modify different bioids Reagent is learned to detect different samples to be tested, or multi-parameter detection can be carried out simultaneously and increased without repeated acquisition sample The diversity of test.
2, electrode group is set in the two sides of substrate, the two sides of substrate can detecte different samples to be tested, increase The diversity of test.
3, four end faces of substrate can detecte sample to be tested, can detect four kinds of different samples to be tested simultaneously, or Person carries out the detection of four kinds of parameters to a kind of sample to be tested.
4, for same sample, front and back sides, the two sides of electrode test piece can quickly be detected to obtain testing result, just In comparative analysis detection data, the complexity of detection is effectively reduced, improves the accuracy of detection.
5, electrochemical electrode test piece is made to the multi-parameter detecting electrode test piece of polyhedral structure, improves the benefit of electrode test piece With rate, the cost of manufacture of electrode test piece is reduced.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model.
Fig. 2 is the front view of electrode test piece.
Fig. 3 is the sectional view along A-A in Fig. 2.
It is identified in figure: substrate 1, detection slot 11, working electrode 21, auxiliary electrode 22, electrode terminal 212, conducting part 213, Reacting part 211, reference electrode 23, recognition terminal 24, siphon cover board 25.
Specific embodiment
The present invention will be further described below with reference to the accompanying drawings and specific embodiments.
Embodiment 1
As depicted in figs. 1 and 2, a kind of electrochemical sensor electrodes test piece of multi-parameter detection, including substrate 1 and electrode Group, electrode group include at least working electrode 21 and auxiliary electrode 22, and electrode group is located on two opposite end faces of substrate 1.Work Electrode 21 and auxiliary electrode 22 form measure loop, generate electric current and capture the concentration that electric signal is converted into sample to be tested again.Relatively Two end faces refer to the obverse and reverse of substrate 1.Different biochemistries can be modified for front and back sides working electrode test piece Reagent tests different samples, increases the diversity of test.Without repeated acquisition sample, realize that a kind of sample is two-parameter Detection.
As shown in Figure 1, opposite two end faces of substrate 1 refer to that the obverse and reverse of substrate 1, obverse and reverse are respectively provided with one A electrode group.Working electrode 21 and auxiliary electrode 22 form measure loop, generate electric current capture electric signal and are converted into again to test sample This concentration.
As shown in Figure 1, electrode group further includes reference electrode 23.Working electrode 21 and reference electrode 23 constitute one it is obstructed or Substantially the system being powered less measures the electrode potential of working electrode using the stability of 23 current potential of reference electrode.Preferably, electric Pole group further includes detecting electrode.Detecting electrode has short-circuit self-checking function or is loaded insufficient detection function, if detecting electrode has When having short-circuit self-checking function, i.e., when test strips be inserted into detector when, judged if the test paper is used or short-circuit for Short circuit can not continue to use.If detecting electrode has sample-adding deficiency detection function, when the sample to be tested that test strips are added is insufficient When, instrument can then show that sample-adding amount deficiency need to mend additional sample size at the appointed time and can accurately test.The electrochemistry passes Sensor electrode test piece can be in response to the different number of electrode of electrochemical action demand difference collocation.
As one embodiment, the working electrode 21 in the both ends of the surface of substrate 1 is drawn by respective conducting wire, auxiliary electrode 22 Parallel connection, 22 parallel connection of auxiliary electrode refer to that the auxiliary electrode in 1 both ends of the surface of substrate can share a conducting wire, auxiliary electrode 22 with appoint What working electrode 21 may be constructed measure loop.
As a specific embodiment, two end faces of substrate 1 are equipped with recognition terminal 24, and recognition terminal 24 is located at work Make between electrode 21 and auxiliary electrode 22, as shown in Figure 2.One and only one recognition terminal 24 of each end face and it is neighbouring it One electrode terminal has electrical connection, to achieve the effect that identification.For example, recognition terminal 24 is only electrical with adjacent working electrode 21 Connection.
As a specific embodiment, as shown in Fig. 2, two end faces of the substrate 1 are equipped with siphon cover board 25.Institute It states siphon cover board 25 and pastes two end faces for being covered in the substrate 1 respectively.The siphon cover board 25 is pasted by insulating materials It is covered in hydrophilic film and is made, gap is equipped among insulating materials, forming straight channels is capillary diversion channel.
As one embodiment, as shown in Fig. 2, electrode group further includes reference electrode 23, working electrode 21, auxiliary electrode 22 It is arranged successively with reference electrode 23.Electrode group all has electrode terminal 212, conducting part 213 and reacting part 211, electrode terminal 212, conducting part 213 and reacting part 211 are sequentially connected, i.e., working electrode 21, auxiliary electrode 22 and reference electrode 23 all have electricity Extreme son 212, conducting part 213 and reacting part 211.As a preferred option, the reacting part of working electrode 21 and auxiliary electrode 22 211 opposite bendings, opposite bending facilitate detection.
As a specific embodiment, the positive working electrode 21 of substrate 1, auxiliary electrode 22, recognition terminal 24, reference The working electrode 21 of electrode 23 and reverse side, auxiliary electrode 22, recognition terminal 23, reference electrode 23 put in order on the contrary, to reach The effect that can be worked normally to positive-negative connected.
The working electrode 21 being capable of modified biological chemical reagent.The biological chemical reagent can aoxidize for glucose It is enzyme, mutarotase, glucose dehydrogenase, lactate oxidase, urate oxidase, cholesterol oxidase, phosphatidase, aminoacidase, peppery Any one or more of enzymes such as root peroxidase, beta-hydroxybutyric dehydrogenase.The modified biological chemistry on multi-panel working electrode Reagent, ingredient reacts in the biological chemical reagent and sample to be tested of modification, is analyzed after generating electric current, can obtain to The ingredient of test sample sheet is more convenient accurate;When the biological chemical reagent of modification is glucose oxidase, Portugal in sample can detect The concentration of grape sugar;The concentration that can detect lactic acid in sample when the biological chemical reagent of modification is lactate oxidase, when modification When biological chemical reagent is urate oxidase, the concentration of uric acid in sample can detect.
When modified biological chemical reagent composition is identical on two working electrode of front and back sides, biological chemical reagent ingredient is grape When carbohydrate oxidase, working principle are as follows:
(1) the detection drop detection sample of sample one is taken to pass through the biological chemical reagent modified on the sucking of capillary diversion channel and electrode Ingredient reacts.
It (2) is I by the front-side current that electrochemical workstation detects1
It (3) is I by the reverse side electric current that electrochemical workstation detects2
(4) electric current is made the difference enable I=| I1-I2|, wherein current difference I represents the correctness of testing result, is worth smaller, inspection It is higher to survey result accuracy.The concentration for calculating glucose in detection sample can be corresponded to.
When modified biological chemical reagent composition is not identical on two working electrode of front and back sides, biological chemical reagent ingredient difference When for glucose oxidase with urate oxidase, working principle are as follows:
(1) the detection drop detection sample of sample one is taken to pass through the biological chemical reagent modified on the sucking of capillary diversion channel and electrode Ingredient reacts.
It (2) is I by the front-side current that electrochemical workstation detects1
It (3) is I by the reverse side electric current that electrochemical workstation detects2
Pass through I1With I2Value can directly calculate separately out detection sample in the concentration of glucose and the concentration of uric acid.
Embodiment 2
The present embodiment the difference from embodiment 1 is that: be respectively provided with an electrode group in two opposite sides of substrate 1.? The two sides of substrate 1 are respectively provided with an electrode group, and the detection of multiple samples or same sample multiple parameters may be implemented.Substrate 1 two opposite sides refer to the left side and right side of substrate 1.
As a specific embodiment, the electrode group of two opposite sides of substrate 1 is located in detection slot 11 and has The exposed face contacted with substance to be detected.Detection slot 11 is set in two sides, the detection slot 11 of groove structure can prevent to be measured Sample outflow, referring to Fig. 3.Specifically, 11 one end of detection slot is equipped with the adding mouth for adding sample to be tested.
As a specific embodiment, two sides of substrate 1 are equipped with recognition terminal 24, and recognition terminal 24 is located at work Make between electrode 21 and auxiliary electrode 22.One and only one recognition terminal 24 of the two sides has with one of neighbouring electrode terminal Electrical connection, to achieve the effect that identification.For example, recognition terminal 24 is only electrically connected with adjacent working electrode 21.
As a specific embodiment, the working electrode 21 of 1 two sides of substrate, auxiliary electrode 22, recognition terminal 24, ginseng It is more suitable with the working electrode 21 of reverse side, auxiliary electrode 22, recognition terminal 23, the arrangement of reference electrode 23 than putting in order for electrode 23 Sequence is on the contrary, to have the function that left and right connects and can work normally.
As a specific embodiment, two sides of the substrate 1 are equipped with siphon cover board 25.
As one embodiment, the both ends of the surface of substrate 1 and the working electrode 21 on two sides are drawn by respective conducting wire, Auxiliary electrode 22 is in parallel, and 22 parallel connection of auxiliary electrode refers to that the auxiliary electrode 22 on 1 both ends of the surface of substrate and two sides can share One conducting wire, auxiliary electrode 22 may be constructed measure loop with any one working electrode 21.
As a specific embodiment, substrate 1 uses plastic material, such as PBT plastic, and substrate 1 has certain thickness Degree, substrate 1 wrap electrode group, meet the placement width of two sides electrode group.
When front and back sides, left and right side working electrode on modified biological chemical reagent composition it is not identical, can correspond to and detect Four kinds of different parameters of sample to be tested of the same race, or the parameter of different samples to be tested.
Content described in this specification embodiment is only an enumeration of the implementation forms of the utility model concept, this is practical new The protection scope of type should not be construed as being limited to the specific forms stated in the embodiments, the protection scope of the utility model also and In those skilled in the art according to the utility model design it is conceivable that equivalent technologies mean.

Claims (8)

1. a kind of electrochemical sensor electrodes test piece of multi-parameter detection, which is characterized in that including substrate and electrode group, electrode group Including at least working electrode and auxiliary electrode, an electrode group is respectively provided in the opposite both ends of the surface of substrate.
2. a kind of electrochemical sensor electrodes test piece of multi-parameter detection as described in claim 1, which is characterized in that substrate two Side is respectively provided with an electrode group.
3. a kind of electrochemical sensor electrodes test piece of multi-parameter detection as claimed in claim 2, which is characterized in that work electricity Recognition terminal is equipped between pole and auxiliary electrode.
4. a kind of electrochemical sensor electrodes test piece of multi-parameter detection as claimed in claim 3, which is characterized in that Mei Ge electricity Pole group also has reference electrode.
5. a kind of electrochemical sensor electrodes test piece of multi-parameter detection as claimed in claim 4, which is characterized in that substrate two Working electrode, auxiliary electrode, recognition terminal and the reference electrode of end face put in order on the contrary;The work electricity of substrate two sides Pole, auxiliary electrode, recognition terminal and reference electricity put in order on the contrary.
6. a kind of electrochemical sensor electrodes test piece of multi-parameter detection as described in claim 1, which is characterized in that electrode group With electrode terminal, conducting part and reacting part, electrode terminal, conducting part and reacting part are sequentially connected.
7. a kind of electrochemical sensor electrodes test piece of multi-parameter detection as claimed in claim 6, which is characterized in that substrate two Side is respectively provided with detection slot, and reactive site is in detection slot and exposing to detection slot.
8. a kind of electrochemical sensor electrodes test piece of multi-parameter detection as claimed in claim 2, which is characterized in that substrate Both ends of the surface and two sides are equipped with siphon cover board.
CN201821421743.6U 2018-08-31 2018-08-31 A kind of electrochemical sensor electrodes test piece of multi-parameter detection Active CN209148584U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109358101A (en) * 2018-08-31 2019-02-19 浙江大学山东工业技术研究院 A kind of electrochemical sensor electrodes test piece of multi-parameter detection
GB2591743A (en) * 2020-01-28 2021-08-11 Univ Of The West Of England Bristol Analyte detection system

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109358101A (en) * 2018-08-31 2019-02-19 浙江大学山东工业技术研究院 A kind of electrochemical sensor electrodes test piece of multi-parameter detection
GB2591743A (en) * 2020-01-28 2021-08-11 Univ Of The West Of England Bristol Analyte detection system

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